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Network neighborhood for query Sequence : ZMY15_HUMAN

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ZMY15_HUMAN
SwissProt Accessions	Q9H091	Gene names	ZMYND15
Domain Architecture	No domain graphic available
Description	Zinc finger MYND domain-containing protein 15.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ZMY15_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	53	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H091	Gene names	ZMYND15
Domain Architecture	No domain graphic available
Description	Zinc finger MYND domain-containing protein 15.

SMYD4_HUMAN
θ value	0.0252991 (rank : 2)	NC score	0.141107 (rank : 2)
Query Neighborhood Hits	53	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IYR2, Q8N1P2, Q8NAT0, Q96LV4, Q96PV2	Gene names	SMYD4, KIAA1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

CHD3_HUMAN
θ value	0.0736092 (rank : 3)	NC score	0.036918 (rank : 32)
Query Neighborhood Hits	53	Target Neighborhood Hits	397	Shared Neighborhood Hits	10
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

ERIC1_HUMAN
θ value	0.125558 (rank : 4)	NC score	0.097833 (rank : 4)
Query Neighborhood Hits	53	Target Neighborhood Hits	364	Shared Neighborhood Hits	12
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

RLF_HUMAN
θ value	0.125558 (rank : 5)	NC score	0.026985 (rank : 38)
Query Neighborhood Hits	53	Target Neighborhood Hits	775	Shared Neighborhood Hits	4
SwissProt Accessions	Q13129, Q9NU60	Gene names	RLF
Domain Architecture	No domain graphic available
Description	Zinc finger protein Rlf (Rearranged L-myc fusion gene protein) (Zn-15- related protein).

SMYD4_MOUSE
θ value	0.365318 (rank : 6)	NC score	0.124067 (rank : 3)
Query Neighborhood Hits	53	Target Neighborhood Hits	85	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BTK5, Q3U3Z8, Q501N5, Q5SWN4, Q69Z60, Q8BMP3	Gene names	Smyd4, Kiaa1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

TACC1_HUMAN
θ value	0.365318 (rank : 7)	NC score	0.038933 (rank : 30)
Query Neighborhood Hits	53	Target Neighborhood Hits	597	Shared Neighborhood Hits	3
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

LEO1_HUMAN
θ value	0.47712 (rank : 8)	NC score	0.062158 (rank : 11)
Query Neighborhood Hits	53	Target Neighborhood Hits	958	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LRRF1_MOUSE
θ value	0.47712 (rank : 9)	NC score	0.066039 (rank : 8)
Query Neighborhood Hits	53	Target Neighborhood Hits	440	Shared Neighborhood Hits	12
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

UBP8_MOUSE
θ value	0.47712 (rank : 10)	NC score	0.031204 (rank : 37)
Query Neighborhood Hits	53	Target Neighborhood Hits	362	Shared Neighborhood Hits	10
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

ASXL1_MOUSE
θ value	0.62314 (rank : 11)	NC score	0.059471 (rank : 13)
Query Neighborhood Hits	53	Target Neighborhood Hits	182	Shared Neighborhood Hits	5
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

NSBP1_MOUSE
θ value	0.62314 (rank : 12)	NC score	0.066200 (rank : 7)
Query Neighborhood Hits	53	Target Neighborhood Hits	681	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

ANKY1_HUMAN
θ value	0.813845 (rank : 13)	NC score	0.058554 (rank : 18)
Query Neighborhood Hits	53	Target Neighborhood Hits	248	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

PSIP1_MOUSE
θ value	0.813845 (rank : 14)	NC score	0.055623 (rank : 19)
Query Neighborhood Hits	53	Target Neighborhood Hits	313	Shared Neighborhood Hits	11
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

DEAF1_HUMAN
θ value	1.38821 (rank : 15)	NC score	0.064453 (rank : 9)
Query Neighborhood Hits	53	Target Neighborhood Hits	67	Shared Neighborhood Hits	10
SwissProt Accessions	O75398, O15152, O75399, O75510, O75511, O75512, O75513, Q9UET1	Gene names	DEAF1, SPN, ZMYND5
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5).

SEM6B_HUMAN
θ value	1.38821 (rank : 16)	NC score	0.018272 (rank : 47)
Query Neighborhood Hits	53	Target Neighborhood Hits	187	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

NIPBL_HUMAN
θ value	1.81305 (rank : 17)	NC score	0.044522 (rank : 28)
Query Neighborhood Hits	53	Target Neighborhood Hits	1311	Shared Neighborhood Hits	16
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

SMYD1_HUMAN
θ value	1.81305 (rank : 18)	NC score	0.074167 (rank : 6)
Query Neighborhood Hits	53	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NB12	Gene names	SMYD1
Domain Architecture
Description	SET and MYND domain-containing protein 1.

SMYD1_MOUSE
θ value	1.81305 (rank : 19)	NC score	0.074257 (rank : 5)
Query Neighborhood Hits	53	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	P97443, P97442, P97444	Gene names	Smyd1, Bop
Domain Architecture
Description	SET and MYND domain-containing protein 1 (Zinc-finger protein BOP) (m- BOP) (CD8b-opposite).

M3K10_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.005458 (rank : 57)
Query Neighborhood Hits	53	Target Neighborhood Hits	1071	Shared Neighborhood Hits	5
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

OXRP_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.026944 (rank : 39)
Query Neighborhood Hits	53	Target Neighborhood Hits	544	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

SYTL1_MOUSE
θ value	2.36792 (rank : 22)	NC score	0.024340 (rank : 41)
Query Neighborhood Hits	53	Target Neighborhood Hits	314	Shared Neighborhood Hits	8
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

TCP10_HUMAN
θ value	2.36792 (rank : 23)	NC score	0.046576 (rank : 27)
Query Neighborhood Hits	53	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

ANK2_HUMAN
θ value	3.0926 (rank : 24)	NC score	0.014794 (rank : 55)
Query Neighborhood Hits	53	Target Neighborhood Hits	1615	Shared Neighborhood Hits	18
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ASGR1_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.017155 (rank : 49)
Query Neighborhood Hits	53	Target Neighborhood Hits	137	Shared Neighborhood Hits	2
SwissProt Accessions	P07306	Gene names	ASGR1
Domain Architecture
Description	Asialoglycoprotein receptor 1 (ASGPR 1) (ASGP-R 1) (Hepatic lectin H1).

CASP1_MOUSE
θ value	3.0926 (rank : 26)	NC score	0.024925 (rank : 40)
Query Neighborhood Hits	53	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	P29452	Gene names	Casp1, Il1bc
Domain Architecture
Description	Caspase-1 precursor (EC 3.4.22.36) (CASP-1) (Interleukin-1 beta convertase) (IL-1BC) (IL-1 beta-converting enzyme) (ICE) (Interleukin- 1 beta-converting enzyme) (p45) [Contains: Caspase-1 p20 subunit; Caspase-1 p10 subunit].

RGS3_HUMAN
θ value	3.0926 (rank : 27)	NC score	0.016487 (rank : 50)
Query Neighborhood Hits	53	Target Neighborhood Hits	1375	Shared Neighborhood Hits	12
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

TCF7_MOUSE
θ value	3.0926 (rank : 28)	NC score	0.023697 (rank : 42)
Query Neighborhood Hits	53	Target Neighborhood Hits	277	Shared Neighborhood Hits	4
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

TXND2_MOUSE
θ value	3.0926 (rank : 29)	NC score	0.038001 (rank : 31)
Query Neighborhood Hits	53	Target Neighborhood Hits	828	Shared Neighborhood Hits	19
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

CMC1_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.020194 (rank : 46)
Query Neighborhood Hits	53	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BH59	Gene names	Slc25a12, Aralar1
Domain Architecture
Description	Calcium-binding mitochondrial carrier protein Aralar1 (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12).

GDF1_MOUSE
θ value	4.03905 (rank : 31)	NC score	0.016434 (rank : 51)
Query Neighborhood Hits	53	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	P20863	Gene names	Gdf1, Gdf-1
Domain Architecture
Description	Embryonic growth/differentiation factor 1 precursor (GDF-1).

GON4L_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.035490 (rank : 33)
Query Neighborhood Hits	53	Target Neighborhood Hits	555	Shared Neighborhood Hits	16
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

GPAA1_HUMAN
θ value	4.03905 (rank : 33)	NC score	0.035291 (rank : 34)
Query Neighborhood Hits	53	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	O43292, Q9NSS0, Q9UQ31	Gene names	GPAA1, GAA1
Domain Architecture
Description	Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (hGAA1).

LEO1_MOUSE
θ value	4.03905 (rank : 34)	NC score	0.051805 (rank : 23)
Query Neighborhood Hits	53	Target Neighborhood Hits	946	Shared Neighborhood Hits	18
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

ATPF2_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.034081 (rank : 35)
Query Neighborhood Hits	53	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N5M1, Q6XYC7	Gene names	ATPAF2, ATP12
Domain Architecture	No domain graphic available
Description	ATP synthase mitochondrial F1 complex assembly factor 2, mitochondrial precursor (ATP12 homolog).

CSTFT_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.013867 (rank : 56)
Query Neighborhood Hits	53	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0L4, O75174, Q53HK6, Q7LGE8, Q8N6T1	Gene names	CSTF2T, KIAA0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

IWS1_HUMAN
θ value	5.27518 (rank : 37)	NC score	0.031940 (rank : 36)
Query Neighborhood Hits	53	Target Neighborhood Hits	1241	Shared Neighborhood Hits	18
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MTG8R_HUMAN
θ value	5.27518 (rank : 38)	NC score	0.059382 (rank : 14)
Query Neighborhood Hits	53	Target Neighborhood Hits	125	Shared Neighborhood Hits	11
SwissProt Accessions	O43439, Q5TGE4, Q5TGE7, Q8IWF3, Q96B06, Q96L00, Q9H436, Q9UJP8, Q9UJP9, Q9UP24	Gene names	CBFA2T2, EHT, MTGR1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1) (Myeloid translocation-related protein 1) (ETO homologous on chromosome 20) (p85).

MTG8R_MOUSE
θ value	5.27518 (rank : 39)	NC score	0.059324 (rank : 15)
Query Neighborhood Hits	53	Target Neighborhood Hits	124	Shared Neighborhood Hits	11
SwissProt Accessions	O70374	Gene names	Cbfa2t2, Cbfa2t2h, Mtgr1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1).

MTG8_HUMAN
θ value	5.27518 (rank : 40)	NC score	0.059073 (rank : 17)
Query Neighborhood Hits	53	Target Neighborhood Hits	87	Shared Neighborhood Hits	11
SwissProt Accessions	Q06455, Q06456, Q14873, Q16239, Q16346, Q16347, Q92479, Q9BRZ0	Gene names	RUNX1T1, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8) (Protein ETO) (Eight twenty one protein) (Cyclin-D-related protein) (Zinc finger MYND domain- containing protein 2).

MTG8_MOUSE
θ value	5.27518 (rank : 41)	NC score	0.059305 (rank : 16)
Query Neighborhood Hits	53	Target Neighborhood Hits	83	Shared Neighborhood Hits	11
SwissProt Accessions	Q61909	Gene names	Runx1t1, Cbfa2t1, Cbfa2t1h, Mtg8
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8).

NPBL_MOUSE
θ value	5.27518 (rank : 42)	NC score	0.043875 (rank : 29)
Query Neighborhood Hits	53	Target Neighborhood Hits	1041	Shared Neighborhood Hits	17
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

SENP3_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.022802 (rank : 43)
Query Neighborhood Hits	53	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4L4, Q96PS4, Q9Y3W9	Gene names	SENP3, SSP3, SUSP3
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3).

SMYD2_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.063558 (rank : 10)
Query Neighborhood Hits	53	Target Neighborhood Hits	37	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NRG4, Q4V765, Q5VSH9	Gene names	SMYD2
Domain Architecture
Description	SET and MYND domain-containing protein 2 (HSKM-B).

APBA1_HUMAN
θ value	6.88961 (rank : 45)	NC score	0.015993 (rank : 52)
Query Neighborhood Hits	53	Target Neighborhood Hits	325	Shared Neighborhood Hits	5
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

CBLC_HUMAN
θ value	6.88961 (rank : 46)	NC score	0.015894 (rank : 53)
Query Neighborhood Hits	53	Target Neighborhood Hits	173	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

DSPP_MOUSE
θ value	6.88961 (rank : 47)	NC score	0.053079 (rank : 22)
Query Neighborhood Hits	53	Target Neighborhood Hits	491	Shared Neighborhood Hits	19
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

CMC1_HUMAN
θ value	8.99809 (rank : 48)	NC score	0.017215 (rank : 48)
Query Neighborhood Hits	53	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	O75746	Gene names	SLC25A12, ARALAR1
Domain Architecture
Description	Calcium-binding mitochondrial carrier protein Aralar1 (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12).

MELPH_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.021784 (rank : 44)
Query Neighborhood Hits	53	Target Neighborhood Hits	145	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

OSBL8_HUMAN
θ value	8.99809 (rank : 50)	NC score	0.015458 (rank : 54)
Query Neighborhood Hits	53	Target Neighborhood Hits	289	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

PCDGC_HUMAN
θ value	8.99809 (rank : 51)	NC score	0.002829 (rank : 58)
Query Neighborhood Hits	53	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	O60330, O15100, Q6UW70, Q9Y5D7	Gene names	PCDHGA12, CDH21, FIB3, KIAA0588
Domain Architecture
Description	Protocadherin gamma A12 precursor (PCDH-gamma-A12) (Cadherin-21) (Fibroblast cadherin 3).

SSF1_MOUSE
θ value	8.99809 (rank : 52)	NC score	0.020977 (rank : 45)
Query Neighborhood Hits	53	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q91YU8	Gene names	Ppan
Domain Architecture
Description	Suppressor of SWI4 1 homolog (Ssf-1) (Peter Pan homolog).

STK39_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.001627 (rank : 59)
Query Neighborhood Hits	53	Target Neighborhood Hits	882	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).

NSBP1_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.054373 (rank : 20)
Query Neighborhood Hits	53	Target Neighborhood Hits	251	Shared Neighborhood Hits	16
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

PTMA_HUMAN
θ value	θ > 10 (rank : 55)	NC score	0.053563 (rank : 21)
Query Neighborhood Hits	53	Target Neighborhood Hits	88	Shared Neighborhood Hits	11
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

PTMA_MOUSE
θ value	θ > 10 (rank : 56)	NC score	0.062003 (rank : 12)
Query Neighborhood Hits	53	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

SMYD2_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.050551 (rank : 25)
Query Neighborhood Hits	53	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R5A0	Gene names	Smyd2
Domain Architecture
Description	SET and MYND domain-containing protein 2.

SMYD3_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.050430 (rank : 26)
Query Neighborhood Hits	53	Target Neighborhood Hits	56	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

SMYD3_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.050848 (rank : 24)
Query Neighborhood Hits	53	Target Neighborhood Hits	51	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CWR2, Q6P7V6, Q8BG90	Gene names	Smyd3, Zmynd1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

Hits sorted by NC score

ZMY15_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	53	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H091	Gene names	ZMYND15
Domain Architecture	No domain graphic available
Description	Zinc finger MYND domain-containing protein 15.

SMYD4_HUMAN
NC score	0.141107 (rank : 2)	θ value	0.0252991 (rank : 2)
Query Neighborhood Hits	53	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IYR2, Q8N1P2, Q8NAT0, Q96LV4, Q96PV2	Gene names	SMYD4, KIAA1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

SMYD4_MOUSE
NC score	0.124067 (rank : 3)	θ value	0.365318 (rank : 6)
Query Neighborhood Hits	53	Target Neighborhood Hits	85	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BTK5, Q3U3Z8, Q501N5, Q5SWN4, Q69Z60, Q8BMP3	Gene names	Smyd4, Kiaa1936
Domain Architecture	No domain graphic available
Description	SET and MYND domain-containing protein 4.

ERIC1_HUMAN
NC score	0.097833 (rank : 4)	θ value	0.125558 (rank : 4)
Query Neighborhood Hits	53	Target Neighborhood Hits	364	Shared Neighborhood Hits	12
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

SMYD1_MOUSE
NC score	0.074257 (rank : 5)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	53	Target Neighborhood Hits	42	Shared Neighborhood Hits	11
SwissProt Accessions	P97443, P97442, P97444	Gene names	Smyd1, Bop
Domain Architecture
Description	SET and MYND domain-containing protein 1 (Zinc-finger protein BOP) (m- BOP) (CD8b-opposite).

SMYD1_HUMAN
NC score	0.074167 (rank : 6)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	53	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NB12	Gene names	SMYD1
Domain Architecture
Description	SET and MYND domain-containing protein 1.

NSBP1_MOUSE
NC score	0.066200 (rank : 7)	θ value	0.62314 (rank : 12)
Query Neighborhood Hits	53	Target Neighborhood Hits	681	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

LRRF1_MOUSE
NC score	0.066039 (rank : 8)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	53	Target Neighborhood Hits	440	Shared Neighborhood Hits	12
SwissProt Accessions	Q3UZ39, O70323, Q3TS94	Gene names	Lrrfip1, Flap
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 1 (LRR FLII- interacting protein 1) (FLI-LRR-associated protein 1) (Flap-1) (H186 FLAP).

DEAF1_HUMAN
NC score	0.064453 (rank : 9)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	53	Target Neighborhood Hits	67	Shared Neighborhood Hits	10
SwissProt Accessions	O75398, O15152, O75399, O75510, O75511, O75512, O75513, Q9UET1	Gene names	DEAF1, SPN, ZMYND5
Domain Architecture
Description	Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1- related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND domain-containing protein 5).

SMYD2_HUMAN
NC score	0.063558 (rank : 10)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	53	Target Neighborhood Hits	37	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NRG4, Q4V765, Q5VSH9	Gene names	SMYD2
Domain Architecture
Description	SET and MYND domain-containing protein 2 (HSKM-B).

LEO1_HUMAN
NC score	0.062158 (rank : 11)	θ value	0.47712 (rank : 8)
Query Neighborhood Hits	53	Target Neighborhood Hits	958	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

PTMA_MOUSE
NC score	0.062003 (rank : 12)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	53	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

ASXL1_MOUSE
NC score	0.059471 (rank : 13)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	53	Target Neighborhood Hits	182	Shared Neighborhood Hits	5
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

MTG8R_HUMAN
NC score	0.059382 (rank : 14)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	53	Target Neighborhood Hits	125	Shared Neighborhood Hits	11
SwissProt Accessions	O43439, Q5TGE4, Q5TGE7, Q8IWF3, Q96B06, Q96L00, Q9H436, Q9UJP8, Q9UJP9, Q9UP24	Gene names	CBFA2T2, EHT, MTGR1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1) (Myeloid translocation-related protein 1) (ETO homologous on chromosome 20) (p85).

MTG8R_MOUSE
NC score	0.059324 (rank : 15)	θ value	5.27518 (rank : 39)
Query Neighborhood Hits	53	Target Neighborhood Hits	124	Shared Neighborhood Hits	11
SwissProt Accessions	O70374	Gene names	Cbfa2t2, Cbfa2t2h, Mtgr1
Domain Architecture
Description	Protein CBFA2T2 (MTG8-like protein) (MTG8-related protein 1).

MTG8_MOUSE
NC score	0.059305 (rank : 16)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	53	Target Neighborhood Hits	83	Shared Neighborhood Hits	11
SwissProt Accessions	Q61909	Gene names	Runx1t1, Cbfa2t1, Cbfa2t1h, Mtg8
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8).

MTG8_HUMAN
NC score	0.059073 (rank : 17)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	53	Target Neighborhood Hits	87	Shared Neighborhood Hits	11
SwissProt Accessions	Q06455, Q06456, Q14873, Q16239, Q16346, Q16347, Q92479, Q9BRZ0	Gene names	RUNX1T1, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Domain Architecture
Description	Protein CBFA2T1 (Protein MTG8) (Protein ETO) (Eight twenty one protein) (Cyclin-D-related protein) (Zinc finger MYND domain- containing protein 2).

ANKY1_HUMAN
NC score	0.058554 (rank : 18)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	53	Target Neighborhood Hits	248	Shared Neighborhood Hits	6
SwissProt Accessions	Q9P2S6, Q8IYX5, Q8NDK5, Q9NX10	Gene names	ANKMY1, TSAL1, ZMYND13
Domain Architecture
Description	Ankyrin repeat and MYND domain-containing protein 1 (Testis-specific ankyrin-like protein 1) (Zinc-finger MYND domain-containing protein 13).

PSIP1_MOUSE
NC score	0.055623 (rank : 19)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	53	Target Neighborhood Hits	313	Shared Neighborhood Hits	11
SwissProt Accessions	Q99JF8, Q3TEJ7, Q3TTD7, Q3UTA1, Q80WQ7, Q99JF7, Q99LR4, Q9CT03	Gene names	Psip1, Ledgf
Domain Architecture	No domain graphic available
Description	PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF).

NSBP1_HUMAN
NC score	0.054373 (rank : 20)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	53	Target Neighborhood Hits	251	Shared Neighborhood Hits	16
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

PTMA_HUMAN
NC score	0.053563 (rank : 21)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	53	Target Neighborhood Hits	88	Shared Neighborhood Hits	11
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

DSPP_MOUSE
NC score	0.053079 (rank : 22)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	53	Target Neighborhood Hits	491	Shared Neighborhood Hits	19
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

LEO1_MOUSE
NC score	0.051805 (rank : 23)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	53	Target Neighborhood Hits	946	Shared Neighborhood Hits	18
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

SMYD3_MOUSE
NC score	0.050848 (rank : 24)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	53	Target Neighborhood Hits	51	Shared Neighborhood Hits	11
SwissProt Accessions	Q9CWR2, Q6P7V6, Q8BG90	Gene names	Smyd3, Zmynd1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

SMYD2_MOUSE
NC score	0.050551 (rank : 25)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	53	Target Neighborhood Hits	41	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R5A0	Gene names	Smyd2
Domain Architecture
Description	SET and MYND domain-containing protein 2.

SMYD3_HUMAN
NC score	0.050430 (rank : 26)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	53	Target Neighborhood Hits	56	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

TCP10_HUMAN
NC score	0.046576 (rank : 27)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	53	Target Neighborhood Hits	134	Shared Neighborhood Hits	4
SwissProt Accessions	Q12799	Gene names	TCP10, TCP10A
Domain Architecture
Description	T-complex protein 10A homolog.

NIPBL_HUMAN
NC score	0.044522 (rank : 28)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	53	Target Neighborhood Hits	1311	Shared Neighborhood Hits	16
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
NC score	0.043875 (rank : 29)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	53	Target Neighborhood Hits	1041	Shared Neighborhood Hits	17
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

TACC1_HUMAN
NC score	0.038933 (rank : 30)	θ value	0.365318 (rank : 7)
Query Neighborhood Hits	53	Target Neighborhood Hits	597	Shared Neighborhood Hits	3
SwissProt Accessions	O75410, Q6Y687, Q86YG7, Q8IUJ2, Q8IUJ3, Q8IUJ4, Q8IZG2, Q8NEY7, Q9UPP9	Gene names	TACC1, KIAA1103
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 1 (Taxin 1) (Gastric cancer antigen Ga55).

TXND2_MOUSE
NC score	0.038001 (rank : 31)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	53	Target Neighborhood Hits	828	Shared Neighborhood Hits	19
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

CHD3_HUMAN
NC score	0.036918 (rank : 32)	θ value	0.0736092 (rank : 3)
Query Neighborhood Hits	53	Target Neighborhood Hits	397	Shared Neighborhood Hits	10
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

GON4L_HUMAN
NC score	0.035490 (rank : 33)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	53	Target Neighborhood Hits	555	Shared Neighborhood Hits	16
SwissProt Accessions	Q3T8J9, Q3T8J8, Q5VYZ5, Q5W0D5, Q6AWA6, Q6P1Q6, Q7Z3L3, Q8IY79, Q9BQI1, Q9HCG6	Gene names	GON4L, GON4, KIAA1606
Domain Architecture	No domain graphic available
Description	GON-4-like protein (GON-4 homolog).

GPAA1_HUMAN
NC score	0.035291 (rank : 34)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	53	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	O43292, Q9NSS0, Q9UQ31	Gene names	GPAA1, GAA1
Domain Architecture
Description	Glycosylphosphatidylinositol anchor attachment 1 protein (GPI anchor attachment protein 1) (GAA1 protein homolog) (hGAA1).

ATPF2_HUMAN
NC score	0.034081 (rank : 35)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	53	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N5M1, Q6XYC7	Gene names	ATPAF2, ATP12
Domain Architecture	No domain graphic available
Description	ATP synthase mitochondrial F1 complex assembly factor 2, mitochondrial precursor (ATP12 homolog).

IWS1_HUMAN
NC score	0.031940 (rank : 36)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	53	Target Neighborhood Hits	1241	Shared Neighborhood Hits	18
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

UBP8_MOUSE
NC score	0.031204 (rank : 37)	θ value	0.47712 (rank : 10)
Query Neighborhood Hits	53	Target Neighborhood Hits	362	Shared Neighborhood Hits	10
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

RLF_HUMAN
NC score	0.026985 (rank : 38)	θ value	0.125558 (rank : 5)
Query Neighborhood Hits	53	Target Neighborhood Hits	775	Shared Neighborhood Hits	4
SwissProt Accessions	Q13129, Q9NU60	Gene names	RLF
Domain Architecture	No domain graphic available
Description	Zinc finger protein Rlf (Rearranged L-myc fusion gene protein) (Zn-15- related protein).

OXRP_HUMAN
NC score	0.026944 (rank : 39)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	53	Target Neighborhood Hits	544	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

CASP1_MOUSE
NC score	0.024925 (rank : 40)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	53	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	P29452	Gene names	Casp1, Il1bc
Domain Architecture
Description	Caspase-1 precursor (EC 3.4.22.36) (CASP-1) (Interleukin-1 beta convertase) (IL-1BC) (IL-1 beta-converting enzyme) (ICE) (Interleukin- 1 beta-converting enzyme) (p45) [Contains: Caspase-1 p20 subunit; Caspase-1 p10 subunit].

SYTL1_MOUSE
NC score	0.024340 (rank : 41)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	53	Target Neighborhood Hits	314	Shared Neighborhood Hits	8
SwissProt Accessions	Q99N80, Q99J26	Gene names	Sytl1, Slp1
Domain Architecture
Description	Synaptotagmin-like protein 1 (Exophilin-7).

TCF7_MOUSE
NC score	0.023697 (rank : 42)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	53	Target Neighborhood Hits	277	Shared Neighborhood Hits	4
SwissProt Accessions	Q00417	Gene names	Tcf7, Tcf-1, Tcf1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

SENP3_HUMAN
NC score	0.022802 (rank : 43)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	53	Target Neighborhood Hits	38	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H4L4, Q96PS4, Q9Y3W9	Gene names	SENP3, SSP3, SUSP3
Domain Architecture
Description	Sentrin-specific protease 3 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP3) (SUMO-1-specific protease 3).

MELPH_HUMAN
NC score	0.021784 (rank : 44)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	53	Target Neighborhood Hits	145	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BV36, Q9HA71	Gene names	MLPH, SLAC2A
Domain Architecture	No domain graphic available
Description	Melanophilin (Exophilin-3) (Synaptotagmin-like protein 2a) (Slp homolog lacking C2 domains a).

SSF1_MOUSE
NC score	0.020977 (rank : 45)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	53	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q91YU8	Gene names	Ppan
Domain Architecture
Description	Suppressor of SWI4 1 homolog (Ssf-1) (Peter Pan homolog).

CMC1_MOUSE
NC score	0.020194 (rank : 46)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	53	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BH59	Gene names	Slc25a12, Aralar1
Domain Architecture
Description	Calcium-binding mitochondrial carrier protein Aralar1 (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12).

SEM6B_HUMAN
NC score	0.018272 (rank : 47)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	53	Target Neighborhood Hits	187	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

CMC1_HUMAN
NC score	0.017215 (rank : 48)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	53	Target Neighborhood Hits	105	Shared Neighborhood Hits	3
SwissProt Accessions	O75746	Gene names	SLC25A12, ARALAR1
Domain Architecture
Description	Calcium-binding mitochondrial carrier protein Aralar1 (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12).

ASGR1_HUMAN
NC score	0.017155 (rank : 49)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	53	Target Neighborhood Hits	137	Shared Neighborhood Hits	2
SwissProt Accessions	P07306	Gene names	ASGR1
Domain Architecture
Description	Asialoglycoprotein receptor 1 (ASGPR 1) (ASGP-R 1) (Hepatic lectin H1).

RGS3_HUMAN
NC score	0.016487 (rank : 50)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	53	Target Neighborhood Hits	1375	Shared Neighborhood Hits	12
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

GDF1_MOUSE
NC score	0.016434 (rank : 51)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	53	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	P20863	Gene names	Gdf1, Gdf-1
Domain Architecture
Description	Embryonic growth/differentiation factor 1 precursor (GDF-1).

APBA1_HUMAN
NC score	0.015993 (rank : 52)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	53	Target Neighborhood Hits	325	Shared Neighborhood Hits	5
SwissProt Accessions	Q02410, O14914, O60570, Q5VYR8	Gene names	APBA1, MINT1, X11
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 1 (Neuron- specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint- 1) (Adapter protein X11alpha).

CBLC_HUMAN
NC score	0.015894 (rank : 53)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	53	Target Neighborhood Hits	173	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULV8, Q8N1E5, Q9Y5Z2, Q9Y5Z3	Gene names	CBLC, CBL3, RNF57
Domain Architecture
Description	Signal transduction protein CBL-C (SH3-binding protein CBL-C) (CBL-3) (RING finger protein 57).

OSBL8_HUMAN
NC score	0.015458 (rank : 54)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	53	Target Neighborhood Hits	289	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

ANK2_HUMAN
NC score	0.014794 (rank : 55)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	53	Target Neighborhood Hits	1615	Shared Neighborhood Hits	18
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

CSTFT_HUMAN
NC score	0.013867 (rank : 56)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	53	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H0L4, O75174, Q53HK6, Q7LGE8, Q8N6T1	Gene names	CSTF2T, KIAA0689
Domain Architecture	No domain graphic available
Description	Cleavage stimulation factor 64 kDa subunit, tau variant (CSTF 64 kDa subunit, tau variant) (CF-1 64 kDa subunit, tau variant) (TauCstF-64).

M3K10_HUMAN
NC score	0.005458 (rank : 57)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	53	Target Neighborhood Hits	1071	Shared Neighborhood Hits	5
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

PCDGC_HUMAN
NC score	0.002829 (rank : 58)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	53	Target Neighborhood Hits	155	Shared Neighborhood Hits	2
SwissProt Accessions	O60330, O15100, Q6UW70, Q9Y5D7	Gene names	PCDHGA12, CDH21, FIB3, KIAA0588
Domain Architecture
Description	Protocadherin gamma A12 precursor (PCDH-gamma-A12) (Cadherin-21) (Fibroblast cadherin 3).

STK39_HUMAN
NC score	0.001627 (rank : 59)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	53	Target Neighborhood Hits	882	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).