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Network neighborhood for query Sequence : GP157_HUMAN

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GP157_HUMAN
SwissProt Accessions	Q5UAW9, Q8WWB8, Q9HA73	Gene names	GPR157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GP157_HUMAN
θ value	3.16172e-154 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	93	Target Neighborhood Hits	93	Shared Neighborhood Hits	93
SwissProt Accessions	Q5UAW9, Q8WWB8, Q9HA73	Gene names	GPR157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GP157_MOUSE
θ value	1.99884e-124 (rank : 2)	NC score	0.973978 (rank : 2)
Query Neighborhood Hits	93	Target Neighborhood Hits	78	Shared Neighborhood Hits	69
SwissProt Accessions	Q8C206, Q8C224	Gene names	Gpr157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

CELR1_HUMAN
θ value	6.43352e-06 (rank : 3)	NC score	0.193552 (rank : 69)
Query Neighborhood Hits	93	Target Neighborhood Hits	613	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

GHRHR_MOUSE
θ value	1.43324e-05 (rank : 4)	NC score	0.336191 (rank : 7)
Query Neighborhood Hits	93	Target Neighborhood Hits	79	Shared Neighborhood Hits	47
SwissProt Accessions	P32082	Gene names	Ghrhr, Grfr
Domain Architecture	No domain graphic available
Description	Growth hormone-releasing hormone receptor precursor (GHRH receptor) (GRF receptor) (GRFR).

CELR1_MOUSE
θ value	3.19293e-05 (rank : 5)	NC score	0.190134 (rank : 70)
Query Neighborhood Hits	93	Target Neighborhood Hits	617	Shared Neighborhood Hits	64
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

GHRHR_HUMAN
θ value	3.19293e-05 (rank : 6)	NC score	0.340335 (rank : 6)
Query Neighborhood Hits	93	Target Neighborhood Hits	78	Shared Neighborhood Hits	48
SwissProt Accessions	Q02643, Q99863	Gene names	GHRHR
Domain Architecture
Description	Growth hormone-releasing hormone receptor precursor (GHRH receptor) (GRF receptor) (GRFR).

CELR2_HUMAN
θ value	0.000461057 (rank : 7)	NC score	0.175894 (rank : 86)
Query Neighborhood Hits	93	Target Neighborhood Hits	657	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR2_MOUSE
θ value	0.00134147 (rank : 8)	NC score	0.180386 (rank : 83)
Query Neighborhood Hits	93	Target Neighborhood Hits	584	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CALCR_MOUSE
θ value	0.00228821 (rank : 9)	NC score	0.330176 (rank : 9)
Query Neighborhood Hits	93	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	Q60755	Gene names	Calcr
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

GP112_HUMAN
θ value	0.00228821 (rank : 10)	NC score	0.270211 (rank : 30)
Query Neighborhood Hits	93	Target Neighborhood Hits	441	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

CRFR1_HUMAN
θ value	0.00298849 (rank : 11)	NC score	0.344580 (rank : 4)
Query Neighborhood Hits	93	Target Neighborhood Hits	82	Shared Neighborhood Hits	48
SwissProt Accessions	P34998, Q13008, Q9UK64	Gene names	CRHR1, CRFR, CRFR1, CRHR
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

CRFR1_MOUSE
θ value	0.00298849 (rank : 12)	NC score	0.343063 (rank : 5)
Query Neighborhood Hits	93	Target Neighborhood Hits	83	Shared Neighborhood Hits	48
SwissProt Accessions	P35347	Gene names	Crhr1, Crhr
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

GP144_HUMAN
θ value	0.00509761 (rank : 13)	NC score	0.330407 (rank : 8)
Query Neighborhood Hits	93	Target Neighborhood Hits	108	Shared Neighborhood Hits	54
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

PTHR1_MOUSE
θ value	0.00665767 (rank : 14)	NC score	0.304908 (rank : 17)
Query Neighborhood Hits	93	Target Neighborhood Hits	90	Shared Neighborhood Hits	48
SwissProt Accessions	P41593, Q62119	Gene names	Pthr1, Pthr
Domain Architecture
Description	Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor).

V1AR_MOUSE
θ value	0.00665767 (rank : 15)	NC score	0.051375 (rank : 129)
Query Neighborhood Hits	93	Target Neighborhood Hits	897	Shared Neighborhood Hits	19
SwissProt Accessions	Q62463, Q62464, Q9QYH2	Gene names	Avpr1a
Domain Architecture
Description	Vasopressin V1a receptor (V1aR) (Vascular/hepatic-type arginine vasopressin receptor) (Antidiuretic hormone receptor 1a) (AVPR V1a).

VIPR2_HUMAN
θ value	0.00665767 (rank : 16)	NC score	0.313038 (rank : 13)
Query Neighborhood Hits	93	Target Neighborhood Hits	97	Shared Neighborhood Hits	46
SwissProt Accessions	P41587, Q13053, Q15870	Gene names	VIPR2, VIP2R
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (Helodermin-preferring VIP receptor).

VIPR1_HUMAN
θ value	0.00869519 (rank : 17)	NC score	0.313604 (rank : 12)
Query Neighborhood Hits	93	Target Neighborhood Hits	84	Shared Neighborhood Hits	46
SwissProt Accessions	P32241, Q15871	Gene names	VIPR1
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 1 precursor (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2).

CD97_MOUSE
θ value	0.0113563 (rank : 18)	NC score	0.240221 (rank : 52)
Query Neighborhood Hits	93	Target Neighborhood Hits	295	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

BAI2_HUMAN
θ value	0.0148317 (rank : 19)	NC score	0.254170 (rank : 47)
Query Neighborhood Hits	93	Target Neighborhood Hits	332	Shared Neighborhood Hits	64
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_MOUSE
θ value	0.0148317 (rank : 20)	NC score	0.255192 (rank : 46)
Query Neighborhood Hits	93	Target Neighborhood Hits	323	Shared Neighborhood Hits	63
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

CELR3_MOUSE
θ value	0.0148317 (rank : 21)	NC score	0.173059 (rank : 87)
Query Neighborhood Hits	93	Target Neighborhood Hits	687	Shared Neighborhood Hits	63
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CALCR_HUMAN
θ value	0.0193708 (rank : 22)	NC score	0.322630 (rank : 11)
Query Neighborhood Hits	93	Target Neighborhood Hits	67	Shared Neighborhood Hits	43
SwissProt Accessions	P30988, O14585, Q13941, Q6DJU8, Q6T712	Gene names	CALCR
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

CD97_HUMAN
θ value	0.0330416 (rank : 23)	NC score	0.216974 (rank : 62)
Query Neighborhood Hits	93	Target Neighborhood Hits	353	Shared Neighborhood Hits	50
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CELR3_HUMAN
θ value	0.0330416 (rank : 24)	NC score	0.170616 (rank : 88)
Query Neighborhood Hits	93	Target Neighborhood Hits	680	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

GP133_HUMAN
θ value	0.0330416 (rank : 25)	NC score	0.348858 (rank : 3)
Query Neighborhood Hits	93	Target Neighborhood Hits	115	Shared Neighborhood Hits	64
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

MTR1L_HUMAN
θ value	0.0330416 (rank : 26)	NC score	0.039930 (rank : 132)
Query Neighborhood Hits	93	Target Neighborhood Hits	1180	Shared Neighborhood Hits	19
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

VIPR1_MOUSE
θ value	0.0330416 (rank : 27)	NC score	0.310351 (rank : 15)
Query Neighborhood Hits	93	Target Neighborhood Hits	89	Shared Neighborhood Hits	48
SwissProt Accessions	P97751, Q9JI40, Q9R1T8	Gene names	Vipr1
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 1 precursor (VIP-R-1) (VPAC1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2).

5HT1A_HUMAN
θ value	0.0431538 (rank : 28)	NC score	0.038884 (rank : 134)
Query Neighborhood Hits	93	Target Neighborhood Hits	887	Shared Neighborhood Hits	19
SwissProt Accessions	P08908, Q6LAE7	Gene names	HTR1A
Domain Architecture
Description	5-hydroxytryptamine 1A receptor (5-HT-1A) (Serotonin receptor 1A) (5- HT1A) (G-21).

BAI1_HUMAN
θ value	0.0431538 (rank : 29)	NC score	0.256774 (rank : 44)
Query Neighborhood Hits	93	Target Neighborhood Hits	375	Shared Neighborhood Hits	61
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
θ value	0.0431538 (rank : 30)	NC score	0.255827 (rank : 45)
Query Neighborhood Hits	93	Target Neighborhood Hits	340	Shared Neighborhood Hits	58
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

EDG1_MOUSE
θ value	0.0736092 (rank : 31)	NC score	0.039347 (rank : 133)
Query Neighborhood Hits	93	Target Neighborhood Hits	867	Shared Neighborhood Hits	18
SwissProt Accessions	O08530, Q9R235	Gene names	Edg1, Lpb1
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-1 (Sphingosine 1-phosphate receptor 1) (S1P1) (Lysophospholipid receptor B1).

FZD3_HUMAN
θ value	0.0736092 (rank : 32)	NC score	0.202875 (rank : 66)
Query Neighborhood Hits	93	Target Neighborhood Hits	74	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NPG1	Gene names	FZD3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (hFz3).

PTHR2_MOUSE
θ value	0.0736092 (rank : 33)	NC score	0.280177 (rank : 26)
Query Neighborhood Hits	93	Target Neighborhood Hits	84	Shared Neighborhood Hits	44
SwissProt Accessions	Q91V95	Gene names	Pthr2
Domain Architecture
Description	Parathyroid hormone receptor precursor (PTH2 receptor).

FZD3_MOUSE
θ value	0.0961366 (rank : 34)	NC score	0.201628 (rank : 67)
Query Neighborhood Hits	93	Target Neighborhood Hits	75	Shared Neighborhood Hits	34
SwissProt Accessions	Q61086	Gene names	Fzd3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (mFz3).

VIPR2_MOUSE
θ value	0.0961366 (rank : 35)	NC score	0.308642 (rank : 16)
Query Neighborhood Hits	93	Target Neighborhood Hits	98	Shared Neighborhood Hits	44
SwissProt Accessions	P41588, P97750	Gene names	Vipr2
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3).

PTHR1_HUMAN
θ value	0.125558 (rank : 36)	NC score	0.301464 (rank : 18)
Query Neighborhood Hits	93	Target Neighborhood Hits	85	Shared Neighborhood Hits	48
SwissProt Accessions	Q03431	Gene names	PTHR1, PTHR
Domain Architecture
Description	Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor).

FZD9_MOUSE
θ value	0.163984 (rank : 37)	NC score	0.185410 (rank : 75)
Query Neighborhood Hits	93	Target Neighborhood Hits	66	Shared Neighborhood Hits	35
SwissProt Accessions	Q9R216, O35494, Q9CX16, Q9R2B3	Gene names	Fzd9, Fzd3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (mFz9) (mFz3).

GP115_MOUSE
θ value	0.163984 (rank : 38)	NC score	0.271103 (rank : 29)
Query Neighborhood Hits	93	Target Neighborhood Hits	69	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

GPR97_MOUSE
θ value	0.163984 (rank : 39)	NC score	0.259255 (rank : 40)
Query Neighborhood Hits	93	Target Neighborhood Hits	89	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

LPHN3_HUMAN
θ value	0.163984 (rank : 40)	NC score	0.266623 (rank : 32)
Query Neighborhood Hits	93	Target Neighborhood Hits	139	Shared Neighborhood Hits	63
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

5HT1A_MOUSE
θ value	0.21417 (rank : 41)	NC score	0.036839 (rank : 136)
Query Neighborhood Hits	93	Target Neighborhood Hits	891	Shared Neighborhood Hits	19
SwissProt Accessions	Q64264, Q60956, Q61617	Gene names	Htr1a, Gpcr18
Domain Architecture
Description	5-hydroxytryptamine 1A receptor (5-HT-1A) (Serotonin receptor 1A) (5- HT1A).

5HT5A_MOUSE
θ value	0.21417 (rank : 42)	NC score	0.036064 (rank : 138)
Query Neighborhood Hits	93	Target Neighborhood Hits	615	Shared Neighborhood Hits	16
SwissProt Accessions	P30966	Gene names	Htr5a, 5ht5a
Domain Architecture
Description	5-hydroxytryptamine 5A receptor (5-HT-5A) (Serotonin receptor 5A) (5- HT-5).

FZD2_HUMAN
θ value	0.21417 (rank : 43)	NC score	0.183866 (rank : 78)
Query Neighborhood Hits	93	Target Neighborhood Hits	57	Shared Neighborhood Hits	32
SwissProt Accessions	Q14332	Gene names	FZD2
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (hFz2) (FzE2).

FZD2_MOUSE
θ value	0.21417 (rank : 44)	NC score	0.183903 (rank : 77)
Query Neighborhood Hits	93	Target Neighborhood Hits	60	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JIP6, Q810M0, Q9JIP5, Q9WUJ2	Gene names	Fzd2, Fzd10
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (mFz2) (mFz10).

FZD7_MOUSE
θ value	0.21417 (rank : 45)	NC score	0.183792 (rank : 79)
Query Neighborhood Hits	93	Target Neighborhood Hits	59	Shared Neighborhood Hits	32
SwissProt Accessions	Q61090	Gene names	Fzd7
Domain Architecture	No domain graphic available
Description	Frizzled-7 precursor (Fz-7) (mFz7).

FZD9_HUMAN
θ value	0.21417 (rank : 46)	NC score	0.183763 (rank : 80)
Query Neighborhood Hits	93	Target Neighborhood Hits	63	Shared Neighborhood Hits	34
SwissProt Accessions	O00144	Gene names	FZD9, FZD3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (hFz9) (FzE6).

GP115_HUMAN
θ value	0.21417 (rank : 47)	NC score	0.263888 (rank : 36)
Query Neighborhood Hits	93	Target Neighborhood Hits	87	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

CXCR4_HUMAN
θ value	0.279714 (rank : 48)	NC score	0.026984 (rank : 144)
Query Neighborhood Hits	93	Target Neighborhood Hits	707	Shared Neighborhood Hits	16
SwissProt Accessions	P61073, O60835, P30991, P56438, Q9UKN2	Gene names	CXCR4
Domain Architecture
Description	C-X-C chemokine receptor type 4 (CXC-R4) (CXCR-4) (Stromal cell- derived factor 1 receptor) (SDF-1 receptor) (Fusin) (Leukocyte-derived seven transmembrane domain receptor) (LESTR) (LCR1) (FB22) (NPYRL) (HM89) (CD184 antigen).

FZD1_HUMAN
θ value	0.279714 (rank : 49)	NC score	0.184910 (rank : 76)
Query Neighborhood Hits	93	Target Neighborhood Hits	62	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UP38, O94815, Q549T8	Gene names	FZD1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (hFz1) (FzE1).

FZD6_HUMAN
θ value	0.279714 (rank : 50)	NC score	0.197003 (rank : 68)
Query Neighborhood Hits	93	Target Neighborhood Hits	84	Shared Neighborhood Hits	36
SwissProt Accessions	O60353, Q6P9C3	Gene names	FZD6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (hFz6).

FZD7_HUMAN
θ value	0.279714 (rank : 51)	NC score	0.181946 (rank : 81)
Query Neighborhood Hits	93	Target Neighborhood Hits	56	Shared Neighborhood Hits	32
SwissProt Accessions	O75084, O94816, Q96B74	Gene names	FZD7
Domain Architecture
Description	Frizzled-7 precursor (Fz-7) (hFz7) (FzE3).

CALRL_HUMAN
θ value	0.365318 (rank : 52)	NC score	0.286412 (rank : 22)
Query Neighborhood Hits	93	Target Neighborhood Hits	71	Shared Neighborhood Hits	43
SwissProt Accessions	Q16602	Gene names	CALCRL, CGRPR
Domain Architecture
Description	Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1 receptor) (Calcitonin receptor-like receptor).

CCR6_HUMAN
θ value	0.365318 (rank : 53)	NC score	0.028463 (rank : 142)
Query Neighborhood Hits	93	Target Neighborhood Hits	650	Shared Neighborhood Hits	16
SwissProt Accessions	P51684, P78553, Q92846	Gene names	CCR6, CKRL3, CMKBR6, GPR29, STRL22
Domain Architecture
Description	C-C chemokine receptor type 6 (C-C CKR-6) (CC-CKR-6) (CCR-6) (LARC receptor) (GPR-CY4) (GPRCY4) (Chemokine receptor-like 3) (CKR-L3) (DRY6) (G-protein coupled receptor 29) (CD196 antigen).

FZD1_MOUSE
θ value	0.365318 (rank : 54)	NC score	0.185496 (rank : 74)
Query Neighborhood Hits	93	Target Neighborhood Hits	63	Shared Neighborhood Hits	35
SwissProt Accessions	O70421, O08974	Gene names	Fzd1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (mFz1).

FZD8_HUMAN
θ value	0.365318 (rank : 55)	NC score	0.178615 (rank : 84)
Query Neighborhood Hits	93	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H461	Gene names	FZD8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (hFz8).

FZD8_MOUSE
θ value	0.365318 (rank : 56)	NC score	0.178295 (rank : 85)
Query Neighborhood Hits	93	Target Neighborhood Hits	89	Shared Neighborhood Hits	31
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

CXCR4_MOUSE
θ value	0.62314 (rank : 57)	NC score	0.027315 (rank : 143)
Query Neighborhood Hits	93	Target Neighborhood Hits	702	Shared Neighborhood Hits	16
SwissProt Accessions	P70658, O09059, O09062, P70233, P70346, Q4KMW1	Gene names	Cxcr4, Cmkar4, Lestr, Sdf1r
Domain Architecture
Description	C-X-C chemokine receptor type 4 (CXC-R4) (CXCR-4) (Stromal cell- derived factor 1 receptor) (SDF-1 receptor) (Fusin) (Leukocyte-derived seven transmembrane domain receptor) (LESTR) (Pre-B-cell-derived chemokine receptor) (PB-CKR) (CD184 antigen).

EDG1_HUMAN
θ value	0.62314 (rank : 58)	NC score	0.036627 (rank : 137)
Query Neighborhood Hits	93	Target Neighborhood Hits	860	Shared Neighborhood Hits	18
SwissProt Accessions	P21453	Gene names	EDG1
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-1 (Sphingosine 1-phosphate receptor 1) (S1P1).

GPR64_HUMAN
θ value	0.62314 (rank : 59)	NC score	0.290927 (rank : 21)
Query Neighborhood Hits	93	Target Neighborhood Hits	207	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

CRFR2_HUMAN
θ value	1.06291 (rank : 60)	NC score	0.310491 (rank : 14)
Query Neighborhood Hits	93	Target Neighborhood Hits	76	Shared Neighborhood Hits	48
SwissProt Accessions	Q13324, O43461, Q99431	Gene names	CRHR2, CRF2R, CRH2R
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2).

CRFR2_MOUSE
θ value	1.06291 (rank : 61)	NC score	0.323535 (rank : 10)
Query Neighborhood Hits	93	Target Neighborhood Hits	76	Shared Neighborhood Hits	48
SwissProt Accessions	Q60748, Q60783, Q60808	Gene names	Crhr2, Crf2r
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2) (CRF-RB) (CRH- R2).

GP126_HUMAN
θ value	1.06291 (rank : 62)	NC score	0.230634 (rank : 56)
Query Neighborhood Hits	93	Target Neighborhood Hits	187	Shared Neighborhood Hits	60
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

V1AR_HUMAN
θ value	1.06291 (rank : 63)	NC score	0.038552 (rank : 135)
Query Neighborhood Hits	93	Target Neighborhood Hits	891	Shared Neighborhood Hits	18
SwissProt Accessions	P37288	Gene names	AVPR1A, AVPR1
Domain Architecture
Description	Vasopressin V1a receptor (V1aR) (Vascular/hepatic-type arginine vasopressin receptor) (Antidiuretic hormone receptor 1a) (AVPR V1a).

EMR4_MOUSE
θ value	1.38821 (rank : 64)	NC score	0.281373 (rank : 23)
Query Neighborhood Hits	93	Target Neighborhood Hits	191	Shared Neighborhood Hits	47
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

FZD6_MOUSE
θ value	1.38821 (rank : 65)	NC score	0.186037 (rank : 73)
Query Neighborhood Hits	93	Target Neighborhood Hits	135	Shared Neighborhood Hits	35
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

GP110_MOUSE
θ value	1.38821 (rank : 66)	NC score	0.246292 (rank : 49)
Query Neighborhood Hits	93	Target Neighborhood Hits	92	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

FZD10_HUMAN
θ value	1.81305 (rank : 67)	NC score	0.168159 (rank : 91)
Query Neighborhood Hits	93	Target Neighborhood Hits	51	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ULW2	Gene names	FZD10
Domain Architecture
Description	Frizzled-10 precursor (Fz-10) (hFz10) (FzE7).

FZD10_MOUSE
θ value	1.81305 (rank : 68)	NC score	0.168091 (rank : 92)
Query Neighborhood Hits	93	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BKG4	Gene names	Fzd10, Fz10
Domain Architecture	No domain graphic available
Description	Frizzled-10 precursor (Fz-10).

GP128_HUMAN
θ value	1.81305 (rank : 69)	NC score	0.280374 (rank : 25)
Query Neighborhood Hits	93	Target Neighborhood Hits	135	Shared Neighborhood Hits	46
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

PACR_MOUSE
θ value	1.81305 (rank : 70)	NC score	0.296266 (rank : 19)
Query Neighborhood Hits	93	Target Neighborhood Hits	83	Shared Neighborhood Hits	48
SwissProt Accessions	P70205	Gene names	Adcyap1r1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide type I receptor precursor (PACAP type I receptor) (PACAP-R-1).

RECQ4_HUMAN
θ value	1.81305 (rank : 71)	NC score	0.020874 (rank : 148)
Query Neighborhood Hits	93	Target Neighborhood Hits	177	Shared Neighborhood Hits	2
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

CABL2_MOUSE
θ value	2.36792 (rank : 72)	NC score	0.025253 (rank : 146)
Query Neighborhood Hits	93	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K3M5	Gene names	Cables2
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

GP110_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.238873 (rank : 53)
Query Neighborhood Hits	93	Target Neighborhood Hits	87	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

CXCR5_MOUSE
θ value	4.03905 (rank : 74)	NC score	0.025416 (rank : 145)
Query Neighborhood Hits	93	Target Neighborhood Hits	705	Shared Neighborhood Hits	16
SwissProt Accessions	Q04683	Gene names	Blr1, Cxcr5, Gpcr6
Domain Architecture
Description	C-X-C chemokine receptor type 5 (CXC-R5) (CXCR-5) (Burkitt lymphoma receptor 1 homolog) (CD185 antigen).

FZD4_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.161474 (rank : 96)
Query Neighborhood Hits	93	Target Neighborhood Hits	54	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ULV1, Q6S9E4	Gene names	FZD4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (hFz4) (FzE4).

FZD4_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.161681 (rank : 95)
Query Neighborhood Hits	93	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	Q61088	Gene names	Fzd4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (mFz4).

GPR3_MOUSE
θ value	4.03905 (rank : 77)	NC score	0.035542 (rank : 139)
Query Neighborhood Hits	93	Target Neighborhood Hits	584	Shared Neighborhood Hits	15
SwissProt Accessions	P35413	Gene names	Gpr3, Gpcr3
Domain Architecture
Description	Probable G-protein coupled receptor 3 (GPCR21).

GPR64_MOUSE
θ value	4.03905 (rank : 78)	NC score	0.280810 (rank : 24)
Query Neighborhood Hits	93	Target Neighborhood Hits	156	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

PTHR2_HUMAN
θ value	4.03905 (rank : 79)	NC score	0.278532 (rank : 27)
Query Neighborhood Hits	93	Target Neighborhood Hits	81	Shared Neighborhood Hits	44
SwissProt Accessions	P49190, Q8N429	Gene names	PTHR2
Domain Architecture
Description	Parathyroid hormone receptor precursor (PTH2 receptor).

SMO_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.168926 (rank : 90)
Query Neighborhood Hits	93	Target Neighborhood Hits	61	Shared Neighborhood Hits	27
SwissProt Accessions	Q99835	Gene names	SMO, SMOH
Domain Architecture
Description	Smoothened homolog precursor (SMO) (Gx protein).

SMO_MOUSE
θ value	4.03905 (rank : 81)	NC score	0.169545 (rank : 89)
Query Neighborhood Hits	93	Target Neighborhood Hits	61	Shared Neighborhood Hits	27
SwissProt Accessions	P56726	Gene names	Smo, Smoh
Domain Architecture	No domain graphic available
Description	Smoothened homolog precursor (SMO).

CHST5_MOUSE
θ value	5.27518 (rank : 82)	NC score	0.011690 (rank : 150)
Query Neighborhood Hits	93	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QUP4	Gene names	Chst5, Gst4
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 5 (EC 2.8.2.-) (N-acetylglucosamine 6-O- sulfotransferase 3) (GlcNAc6ST-3) (Intestinal GlcNAc-6- sulfotransferase) (Intestinal N-acetylglucosamine-6-O- sulfotransferase) (I-GlcNAc6ST) (mIGn6ST) (Galactose/N- acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4) (GST4).

GPR3_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.034654 (rank : 140)
Query Neighborhood Hits	93	Target Neighborhood Hits	578	Shared Neighborhood Hits	15
SwissProt Accessions	P46089	Gene names	GPR3, ACCA
Domain Architecture
Description	Probable G-protein coupled receptor 3 (ACCA orphan receptor).

PACR_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.292112 (rank : 20)
Query Neighborhood Hits	93	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	P41586	Gene names	ADCYAP1R1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide type I receptor precursor (PACAP type I receptor) (PACAP-R-1).

FZD5_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.166271 (rank : 93)
Query Neighborhood Hits	93	Target Neighborhood Hits	71	Shared Neighborhood Hits	31
SwissProt Accessions	Q13467, Q53R22	Gene names	FZD5, HFZ5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (hFz5) (FzE5).

OLF15_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.001018 (rank : 153)
Query Neighborhood Hits	93	Target Neighborhood Hits	752	Shared Neighborhood Hits	11
SwissProt Accessions	P23275	Gene names	Olfr15
Domain Architecture
Description	Olfactory receptor 15 (Odorant receptor OR3).

GLP1R_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.265356 (rank : 34)
Query Neighborhood Hits	93	Target Neighborhood Hits	84	Shared Neighborhood Hits	46
SwissProt Accessions	P43220, Q99669	Gene names	GLP1R
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

GP143_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.040104 (rank : 131)
Query Neighborhood Hits	93	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	P51810	Gene names	GPR143, OA1
Domain Architecture
Description	G-protein coupled receptor 143 (Ocular albinism type 1 protein).

GP143_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.030432 (rank : 141)
Query Neighborhood Hits	93	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P70259, O89031	Gene names	Gpr143, Oa1
Domain Architecture
Description	G-protein coupled receptor 143 (Ocular albinism type 1 protein homolog) (MOA1).

MALL_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.014059 (rank : 149)
Query Neighborhood Hits	93	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q13021, Q9BTU0	Gene names	MALL, BENE
Domain Architecture
Description	MAL-like protein (Protein BENE).

MLL2_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.005379 (rank : 151)
Query Neighborhood Hits	93	Target Neighborhood Hits	1788	Shared Neighborhood Hits	11
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

OPN3_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.024037 (rank : 147)
Query Neighborhood Hits	93	Target Neighborhood Hits	782	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WUK7, Q3V0X3	Gene names	Opn3, Ecpn
Domain Architecture
Description	Opsin-3 (Encephalopsin) (Panopsin).

OR6X1_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.002935 (rank : 152)
Query Neighborhood Hits	93	Target Neighborhood Hits	771	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NH79, Q6IFA0	Gene names	OR6X1
Domain Architecture
Description	Olfactory receptor 6X1 (Olfactory receptor OR11-270).

BAI3_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.225175 (rank : 58)
Query Neighborhood Hits	93	Target Neighborhood Hits	246	Shared Neighborhood Hits	56
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.224980 (rank : 59)
Query Neighborhood Hits	93	Target Neighborhood Hits	250	Shared Neighborhood Hits	56
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

CAD17_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.051598 (rank : 128)
Query Neighborhood Hits	93	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R100	Gene names	Cdh17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (BILL- cadherin) (P130).

CAD23_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.058549 (rank : 117)
Query Neighborhood Hits	93	Target Neighborhood Hits	197	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CAD23_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.058630 (rank : 116)
Query Neighborhood Hits	93	Target Neighborhood Hits	208	Shared Neighborhood Hits	7
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CALRL_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.274534 (rank : 28)
Query Neighborhood Hits	93	Target Neighborhood Hits	71	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R1W5, Q9QXH8, Q9WUP2	Gene names	Calcrl, Crlr
Domain Architecture
Description	Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1 receptor) (Calcitonin receptor-like receptor).

CBPZ_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.055461 (rank : 122)
Query Neighborhood Hits	93	Target Neighborhood Hits	69	Shared Neighborhood Hits	21
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CRUM1_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.052372 (rank : 127)
Query Neighborhood Hits	93	Target Neighborhood Hits	457	Shared Neighborhood Hits	10
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.053230 (rank : 124)
Query Neighborhood Hits	93	Target Neighborhood Hits	444	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

ELTD1_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.234383 (rank : 54)
Query Neighborhood Hits	93	Target Neighborhood Hits	269	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ELTD1_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.208043 (rank : 64)
Query Neighborhood Hits	93	Target Neighborhood Hits	288	Shared Neighborhood Hits	48
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR1_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.180961 (rank : 82)
Query Neighborhood Hits	93	Target Neighborhood Hits	382	Shared Neighborhood Hits	51
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

EMR1_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.190099 (rank : 71)
Query Neighborhood Hits	93	Target Neighborhood Hits	349	Shared Neighborhood Hits	50
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.188997 (rank : 72)
Query Neighborhood Hits	93	Target Neighborhood Hits	345	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

EMR3_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.260866 (rank : 39)
Query Neighborhood Hits	93	Target Neighborhood Hits	245	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

FAT2_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.053890 (rank : 123)
Query Neighborhood Hits	93	Target Neighborhood Hits	507	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

FATH_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.052799 (rank : 125)
Query Neighborhood Hits	93	Target Neighborhood Hits	570	Shared Neighborhood Hits	10
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

FZD5_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.162679 (rank : 94)
Query Neighborhood Hits	93	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	Q9EQD0, O08975, Q8BMR2, Q8CHK9	Gene names	Fzd5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (mFz5).

GIPR_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.258534 (rank : 41)
Query Neighborhood Hits	93	Target Neighborhood Hits	71	Shared Neighborhood Hits	42
SwissProt Accessions	P48546, Q14401, Q16400, Q9UPI1	Gene names	GIPR
Domain Architecture
Description	Gastric inhibitory polypeptide receptor precursor (GIP-R) (Glucose- dependent insulinotropic polypeptide receptor).

GLP1R_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.264775 (rank : 35)
Query Neighborhood Hits	93	Target Neighborhood Hits	80	Shared Neighborhood Hits	46
SwissProt Accessions	O35659	Gene names	Glp1r
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

GLP2R_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.250002 (rank : 48)
Query Neighborhood Hits	93	Target Neighborhood Hits	75	Shared Neighborhood Hits	42
SwissProt Accessions	O95838	Gene names	GLP2R
Domain Architecture
Description	Glucagon-like peptide 2 receptor precursor (GLP-2 receptor) (GLP-2-R) (GLP-2R).

GLR_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.263048 (rank : 37)
Query Neighborhood Hits	93	Target Neighborhood Hits	77	Shared Neighborhood Hits	44
SwissProt Accessions	P47871	Gene names	GCGR
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

GLR_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.257700 (rank : 43)
Query Neighborhood Hits	93	Target Neighborhood Hits	79	Shared Neighborhood Hits	44
SwissProt Accessions	Q61606, Q63960	Gene names	Gcgr
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

GP111_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.206204 (rank : 65)
Query Neighborhood Hits	93	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

GP113_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.265360 (rank : 33)
Query Neighborhood Hits	93	Target Neighborhood Hits	102	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

GP114_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.218545 (rank : 61)
Query Neighborhood Hits	93	Target Neighborhood Hits	75	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

GP116_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.224593 (rank : 60)
Query Neighborhood Hits	93	Target Neighborhood Hits	167	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GP123_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.140618 (rank : 99)
Query Neighborhood Hits	93	Target Neighborhood Hits	120	Shared Neighborhood Hits	25
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

GP124_HUMAN
θ value	θ > 10 (rank : 122)	NC score	0.089142 (rank : 112)
Query Neighborhood Hits	93	Target Neighborhood Hits	304	Shared Neighborhood Hits	26
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP124_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.095880 (rank : 110)
Query Neighborhood Hits	93	Target Neighborhood Hits	423	Shared Neighborhood Hits	31
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP125_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.094614 (rank : 111)
Query Neighborhood Hits	93	Target Neighborhood Hits	327	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP125_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.088299 (rank : 113)
Query Neighborhood Hits	93	Target Neighborhood Hits	329	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP128_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.257855 (rank : 42)
Query Neighborhood Hits	93	Target Neighborhood Hits	141	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GP155_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.052502 (rank : 126)
Query Neighborhood Hits	93	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

GPR56_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.231461 (rank : 55)
Query Neighborhood Hits	93	Target Neighborhood Hits	84	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

GPR56_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.213237 (rank : 63)
Query Neighborhood Hits	93	Target Neighborhood Hits	89	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

GPR97_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.228670 (rank : 57)
Query Neighborhood Hits	93	Target Neighborhood Hits	86	Shared Neighborhood Hits	44
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

GPR98_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.161343 (rank : 97)
Query Neighborhood Hits	93	Target Neighborhood Hits	202	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

GPR98_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.147643 (rank : 98)
Query Neighborhood Hits	93	Target Neighborhood Hits	206	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

LPHN1_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.244969 (rank : 50)
Query Neighborhood Hits	93	Target Neighborhood Hits	155	Shared Neighborhood Hits	47
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

LPHN2_HUMAN
θ value	θ > 10 (rank : 134)	NC score	0.240298 (rank : 51)
Query Neighborhood Hits	93	Target Neighborhood Hits	136	Shared Neighborhood Hits	50
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

MFRP_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.060782 (rank : 115)
Query Neighborhood Hits	93	Target Neighborhood Hits	165	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.061693 (rank : 114)
Query Neighborhood Hits	93	Target Neighborhood Hits	166	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

PCD15_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.058222 (rank : 119)
Query Neighborhood Hits	93	Target Neighborhood Hits	289	Shared Neighborhood Hits	6
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

PCD15_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.058298 (rank : 118)
Query Neighborhood Hits	93	Target Neighborhood Hits	262	Shared Neighborhood Hits	6
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

PCD16_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.056009 (rank : 121)
Query Neighborhood Hits	93	Target Neighborhood Hits	245	Shared Neighborhood Hits	6
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

PCDH1_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.050430 (rank : 130)
Query Neighborhood Hits	93	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	Q08174	Gene names	PCDH1
Domain Architecture
Description	Protocadherin-1 precursor (Protocadherin-42) (PC42) (Cadherin-like protein 1).

PCDLK_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.056445 (rank : 120)
Query Neighborhood Hits	93	Target Neighborhood Hits	172	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYE9, Q9NXP8	Gene names	PCLKC
Domain Architecture	No domain graphic available
Description	Protocadherin LKC precursor (PC-LKC).

SCTR_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.267369 (rank : 31)
Query Neighborhood Hits	93	Target Neighborhood Hits	70	Shared Neighborhood Hits	42
SwissProt Accessions	P47872, Q12961, Q13213	Gene names	SCTR
Domain Architecture
Description	Secretin receptor precursor (SCT-R).

SCTR_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.262875 (rank : 38)
Query Neighborhood Hits	93	Target Neighborhood Hits	69	Shared Neighborhood Hits	42
SwissProt Accessions	Q5FWI2, Q80T66	Gene names	Sctr
Domain Architecture	No domain graphic available
Description	Secretin receptor precursor (SCT-R).

SFRP1_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.105410 (rank : 108)
Query Neighborhood Hits	93	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N474, O00546, O14779	Gene names	SFRP1, FRP, FRP1, SARP2
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1) (Frizzled- related protein 1) (FRP-1) (Secreted apoptosis-related protein 2) (SARP-2).

SFRP1_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.105674 (rank : 106)
Query Neighborhood Hits	93	Target Neighborhood Hits	43	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C4U3, O08861, Q8R1J4	Gene names	Sfrp1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1).

SFRP2_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.105254 (rank : 109)
Query Neighborhood Hits	93	Target Neighborhood Hits	46	Shared Neighborhood Hits	19
SwissProt Accessions	Q96HF1, O14778, Q9HAP5	Gene names	SFRP2, FRP2, SARP1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (Frizzled-related protein 2) (FRP-2).

SFRP2_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.105477 (rank : 107)
Query Neighborhood Hits	93	Target Neighborhood Hits	47	Shared Neighborhood Hits	19
SwissProt Accessions	P97299, O08862, O35297	Gene names	Sfrp2, Sarp1, Sdf5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (SDF5 protein).

SFRP3_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.112793 (rank : 103)
Query Neighborhood Hits	93	Target Neighborhood Hits	43	Shared Neighborhood Hits	21
SwissProt Accessions	Q92765, O00181, Q99686	Gene names	FRZB, FIZ, FRE, FRP, FRZB1, SFRP3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP3_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.113007 (rank : 102)
Query Neighborhood Hits	93	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	P97401, O09075, O09093, Q91W58	Gene names	Frzb, Fiz, Fre, Frzb1, Sfrp3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP4_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.115655 (rank : 100)
Query Neighborhood Hits	93	Target Neighborhood Hits	43	Shared Neighborhood Hits	21
SwissProt Accessions	Q6FHJ7, O14877, Q4G124, Q6FHM0, Q6PD64	Gene names	SFRP4, FRPHE
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 4 precursor (sFRP-4) (Frizzled protein, human endometrium) (FrpHE).

SFRP4_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.115522 (rank : 101)
Query Neighborhood Hits	93	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z1N6, Q91ZX9	Gene names	Sfrp4
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related sequence protein 4 precursor (sFRP-4) (Frizzled-related protein 4) (FRP-4).

SFRP5_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.106064 (rank : 105)
Query Neighborhood Hits	93	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T4F7, O14780, Q86TH7	Gene names	SFRP5, FRP1B, SARP3
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5) (Secreted apoptosis-related protein 3) (SARP-3) (Frizzled-related protein 1b) (FRP-1b).

SFRP5_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.106147 (rank : 104)
Query Neighborhood Hits	93	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WU66, Q8K269	Gene names	Sfrp5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5).

Hits sorted by NC score

GP157_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.16172e-154 (rank : 1)
Query Neighborhood Hits	93	Target Neighborhood Hits	93	Shared Neighborhood Hits	93
SwissProt Accessions	Q5UAW9, Q8WWB8, Q9HA73	Gene names	GPR157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GP157_MOUSE
NC score	0.973978 (rank : 2)	θ value	1.99884e-124 (rank : 2)
Query Neighborhood Hits	93	Target Neighborhood Hits	78	Shared Neighborhood Hits	69
SwissProt Accessions	Q8C206, Q8C224	Gene names	Gpr157
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 157.

GP133_HUMAN
NC score	0.348858 (rank : 3)	θ value	0.0330416 (rank : 25)
Query Neighborhood Hits	93	Target Neighborhood Hits	115	Shared Neighborhood Hits	64
SwissProt Accessions	Q6QNK2, Q6ZMQ1, Q7Z7M2, Q86SM4	Gene names	GPR133, PGR25
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 133 precursor (G-protein coupled receptor PGR25).

CRFR1_HUMAN
NC score	0.344580 (rank : 4)	θ value	0.00298849 (rank : 11)
Query Neighborhood Hits	93	Target Neighborhood Hits	82	Shared Neighborhood Hits	48
SwissProt Accessions	P34998, Q13008, Q9UK64	Gene names	CRHR1, CRFR, CRFR1, CRHR
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

CRFR1_MOUSE
NC score	0.343063 (rank : 5)	θ value	0.00298849 (rank : 12)
Query Neighborhood Hits	93	Target Neighborhood Hits	83	Shared Neighborhood Hits	48
SwissProt Accessions	P35347	Gene names	Crhr1, Crhr
Domain Architecture
Description	Corticotropin-releasing factor receptor 1 precursor (CRF-R) (CRF1) (Corticotropin-releasing hormone receptor 1) (CRH-R 1).

GHRHR_HUMAN
NC score	0.340335 (rank : 6)	θ value	3.19293e-05 (rank : 6)
Query Neighborhood Hits	93	Target Neighborhood Hits	78	Shared Neighborhood Hits	48
SwissProt Accessions	Q02643, Q99863	Gene names	GHRHR
Domain Architecture
Description	Growth hormone-releasing hormone receptor precursor (GHRH receptor) (GRF receptor) (GRFR).

GHRHR_MOUSE
NC score	0.336191 (rank : 7)	θ value	1.43324e-05 (rank : 4)
Query Neighborhood Hits	93	Target Neighborhood Hits	79	Shared Neighborhood Hits	47
SwissProt Accessions	P32082	Gene names	Ghrhr, Grfr
Domain Architecture	No domain graphic available
Description	Growth hormone-releasing hormone receptor precursor (GHRH receptor) (GRF receptor) (GRFR).

GP144_HUMAN
NC score	0.330407 (rank : 8)	θ value	0.00509761 (rank : 13)
Query Neighborhood Hits	93	Target Neighborhood Hits	108	Shared Neighborhood Hits	54
SwissProt Accessions	Q7Z7M1, Q86SL4, Q8NH12	Gene names	GPR144, PGR24
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 144 (G-protein coupled receptor PGR24).

CALCR_MOUSE
NC score	0.330176 (rank : 9)	θ value	0.00228821 (rank : 9)
Query Neighborhood Hits	93	Target Neighborhood Hits	76	Shared Neighborhood Hits	47
SwissProt Accessions	Q60755	Gene names	Calcr
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

CRFR2_MOUSE
NC score	0.323535 (rank : 10)	θ value	1.06291 (rank : 61)
Query Neighborhood Hits	93	Target Neighborhood Hits	76	Shared Neighborhood Hits	48
SwissProt Accessions	Q60748, Q60783, Q60808	Gene names	Crhr2, Crf2r
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2) (CRF-RB) (CRH- R2).

CALCR_HUMAN
NC score	0.322630 (rank : 11)	θ value	0.0193708 (rank : 22)
Query Neighborhood Hits	93	Target Neighborhood Hits	67	Shared Neighborhood Hits	43
SwissProt Accessions	P30988, O14585, Q13941, Q6DJU8, Q6T712	Gene names	CALCR
Domain Architecture
Description	Calcitonin receptor precursor (CT-R).

VIPR1_HUMAN
NC score	0.313604 (rank : 12)	θ value	0.00869519 (rank : 17)
Query Neighborhood Hits	93	Target Neighborhood Hits	84	Shared Neighborhood Hits	46
SwissProt Accessions	P32241, Q15871	Gene names	VIPR1
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 1 precursor (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2).

VIPR2_HUMAN
NC score	0.313038 (rank : 13)	θ value	0.00665767 (rank : 16)
Query Neighborhood Hits	93	Target Neighborhood Hits	97	Shared Neighborhood Hits	46
SwissProt Accessions	P41587, Q13053, Q15870	Gene names	VIPR2, VIP2R
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (Helodermin-preferring VIP receptor).

CRFR2_HUMAN
NC score	0.310491 (rank : 14)	θ value	1.06291 (rank : 60)
Query Neighborhood Hits	93	Target Neighborhood Hits	76	Shared Neighborhood Hits	48
SwissProt Accessions	Q13324, O43461, Q99431	Gene names	CRHR2, CRF2R, CRH2R
Domain Architecture
Description	Corticotropin-releasing factor receptor 2 precursor (CRF-R 2) (CRF2) (Corticotropin-releasing hormone receptor 2) (CRH-R 2).

VIPR1_MOUSE
NC score	0.310351 (rank : 15)	θ value	0.0330416 (rank : 27)
Query Neighborhood Hits	93	Target Neighborhood Hits	89	Shared Neighborhood Hits	48
SwissProt Accessions	P97751, Q9JI40, Q9R1T8	Gene names	Vipr1
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 1 precursor (VIP-R-1) (VPAC1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2).

VIPR2_MOUSE
NC score	0.308642 (rank : 16)	θ value	0.0961366 (rank : 35)
Query Neighborhood Hits	93	Target Neighborhood Hits	98	Shared Neighborhood Hits	44
SwissProt Accessions	P41588, P97750	Gene names	Vipr2
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3).

PTHR1_MOUSE
NC score	0.304908 (rank : 17)	θ value	0.00665767 (rank : 14)
Query Neighborhood Hits	93	Target Neighborhood Hits	90	Shared Neighborhood Hits	48
SwissProt Accessions	P41593, Q62119	Gene names	Pthr1, Pthr
Domain Architecture
Description	Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor).

PTHR1_HUMAN
NC score	0.301464 (rank : 18)	θ value	0.125558 (rank : 36)
Query Neighborhood Hits	93	Target Neighborhood Hits	85	Shared Neighborhood Hits	48
SwissProt Accessions	Q03431	Gene names	PTHR1, PTHR
Domain Architecture
Description	Parathyroid hormone/parathyroid hormone-related peptide receptor precursor (PTH/PTHr receptor) (PTH/PTHrP type I receptor).

PACR_MOUSE
NC score	0.296266 (rank : 19)	θ value	1.81305 (rank : 70)
Query Neighborhood Hits	93	Target Neighborhood Hits	83	Shared Neighborhood Hits	48
SwissProt Accessions	P70205	Gene names	Adcyap1r1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide type I receptor precursor (PACAP type I receptor) (PACAP-R-1).

PACR_HUMAN
NC score	0.292112 (rank : 20)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	93	Target Neighborhood Hits	86	Shared Neighborhood Hits	48
SwissProt Accessions	P41586	Gene names	ADCYAP1R1
Domain Architecture
Description	Pituitary adenylate cyclase-activating polypeptide type I receptor precursor (PACAP type I receptor) (PACAP-R-1).

GPR64_HUMAN
NC score	0.290927 (rank : 21)	θ value	0.62314 (rank : 59)
Query Neighborhood Hits	93	Target Neighborhood Hits	207	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

CALRL_HUMAN
NC score	0.286412 (rank : 22)	θ value	0.365318 (rank : 52)
Query Neighborhood Hits	93	Target Neighborhood Hits	71	Shared Neighborhood Hits	43
SwissProt Accessions	Q16602	Gene names	CALCRL, CGRPR
Domain Architecture
Description	Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1 receptor) (Calcitonin receptor-like receptor).

EMR4_MOUSE
NC score	0.281373 (rank : 23)	θ value	1.38821 (rank : 64)
Query Neighborhood Hits	93	Target Neighborhood Hits	191	Shared Neighborhood Hits	47
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

GPR64_MOUSE
NC score	0.280810 (rank : 24)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	93	Target Neighborhood Hits	156	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CJ12, Q8BL10, Q8CJ08, Q8CJ09, Q8CJ10	Gene names	Gpr64, Me6
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (Me6 receptor).

GP128_HUMAN
NC score	0.280374 (rank : 25)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	93	Target Neighborhood Hits	135	Shared Neighborhood Hits	46
SwissProt Accessions	Q96K78, Q86SQ2	Gene names	GPR128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

PTHR2_MOUSE
NC score	0.280177 (rank : 26)	θ value	0.0736092 (rank : 33)
Query Neighborhood Hits	93	Target Neighborhood Hits	84	Shared Neighborhood Hits	44
SwissProt Accessions	Q91V95	Gene names	Pthr2
Domain Architecture
Description	Parathyroid hormone receptor precursor (PTH2 receptor).

PTHR2_HUMAN
NC score	0.278532 (rank : 27)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	93	Target Neighborhood Hits	81	Shared Neighborhood Hits	44
SwissProt Accessions	P49190, Q8N429	Gene names	PTHR2
Domain Architecture
Description	Parathyroid hormone receptor precursor (PTH2 receptor).

CALRL_MOUSE
NC score	0.274534 (rank : 28)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	93	Target Neighborhood Hits	71	Shared Neighborhood Hits	42
SwissProt Accessions	Q9R1W5, Q9QXH8, Q9WUP2	Gene names	Calcrl, Crlr
Domain Architecture
Description	Calcitonin gene-related peptide type 1 receptor precursor (CGRP type 1 receptor) (Calcitonin receptor-like receptor).

GP115_MOUSE
NC score	0.271103 (rank : 29)	θ value	0.163984 (rank : 38)
Query Neighborhood Hits	93	Target Neighborhood Hits	69	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D2L6	Gene names	Gpr115
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 precursor.

GP112_HUMAN
NC score	0.270211 (rank : 30)	θ value	0.00228821 (rank : 10)
Query Neighborhood Hits	93	Target Neighborhood Hits	441	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

SCTR_HUMAN
NC score	0.267369 (rank : 31)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	93	Target Neighborhood Hits	70	Shared Neighborhood Hits	42
SwissProt Accessions	P47872, Q12961, Q13213	Gene names	SCTR
Domain Architecture
Description	Secretin receptor precursor (SCT-R).

LPHN3_HUMAN
NC score	0.266623 (rank : 32)	θ value	0.163984 (rank : 40)
Query Neighborhood Hits	93	Target Neighborhood Hits	139	Shared Neighborhood Hits	63
SwissProt Accessions	Q9HAR2, O94867, Q9NWK5	Gene names	LPHN3, KIAA0768, LEC3
Domain Architecture
Description	Latrophilin-3 precursor (Calcium-independent alpha-latrotoxin receptor 3) (Lectomedin-3).

GP113_HUMAN
NC score	0.265360 (rank : 33)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	93	Target Neighborhood Hits	102	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IZF5, Q6UXT7, Q6UXX3, Q86SL7, Q8IXD8, Q8TDT3	Gene names	GPR113, PGR23
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 113 precursor (G-protein coupled receptor PGR23).

GLP1R_HUMAN
NC score	0.265356 (rank : 34)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	93	Target Neighborhood Hits	84	Shared Neighborhood Hits	46
SwissProt Accessions	P43220, Q99669	Gene names	GLP1R
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

GLP1R_MOUSE
NC score	0.264775 (rank : 35)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	93	Target Neighborhood Hits	80	Shared Neighborhood Hits	46
SwissProt Accessions	O35659	Gene names	Glp1r
Domain Architecture
Description	Glucagon-like peptide 1 receptor precursor (GLP-1 receptor) (GLP-1-R) (GLP-1R).

GP115_HUMAN
NC score	0.263888 (rank : 36)	θ value	0.21417 (rank : 47)
Query Neighborhood Hits	93	Target Neighborhood Hits	87	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IZF3, Q5T5B5, Q5T5B6, Q86SN9, Q8IXE6	Gene names	GPR115, PGR18
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 115 (G-protein coupled receptor PGR18).

GLR_HUMAN
NC score	0.263048 (rank : 37)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	93	Target Neighborhood Hits	77	Shared Neighborhood Hits	44
SwissProt Accessions	P47871	Gene names	GCGR
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

SCTR_MOUSE
NC score	0.262875 (rank : 38)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	93	Target Neighborhood Hits	69	Shared Neighborhood Hits	42
SwissProt Accessions	Q5FWI2, Q80T66	Gene names	Sctr
Domain Architecture	No domain graphic available
Description	Secretin receptor precursor (SCT-R).

EMR3_HUMAN
NC score	0.260866 (rank : 39)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	93	Target Neighborhood Hits	245	Shared Neighborhood Hits	46
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

GPR97_MOUSE
NC score	0.259255 (rank : 40)	θ value	0.163984 (rank : 39)
Query Neighborhood Hits	93	Target Neighborhood Hits	89	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R0T6	Gene names	Gpr97
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor.

GIPR_HUMAN
NC score	0.258534 (rank : 41)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	93	Target Neighborhood Hits	71	Shared Neighborhood Hits	42
SwissProt Accessions	P48546, Q14401, Q16400, Q9UPI1	Gene names	GIPR
Domain Architecture
Description	Gastric inhibitory polypeptide receptor precursor (GIP-R) (Glucose- dependent insulinotropic polypeptide receptor).

GP128_MOUSE
NC score	0.257855 (rank : 42)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	93	Target Neighborhood Hits	141	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BM96, Q80T42	Gene names	Gpr128
Domain Architecture
Description	Probable G-protein coupled receptor 128 precursor.

GLR_MOUSE
NC score	0.257700 (rank : 43)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	93	Target Neighborhood Hits	79	Shared Neighborhood Hits	44
SwissProt Accessions	Q61606, Q63960	Gene names	Gcgr
Domain Architecture
Description	Glucagon receptor precursor (GL-R).

BAI1_HUMAN
NC score	0.256774 (rank : 44)	θ value	0.0431538 (rank : 29)
Query Neighborhood Hits	93	Target Neighborhood Hits	375	Shared Neighborhood Hits	61
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI1_MOUSE
NC score	0.255827 (rank : 45)	θ value	0.0431538 (rank : 30)
Query Neighborhood Hits	93	Target Neighborhood Hits	340	Shared Neighborhood Hits	58
SwissProt Accessions	Q3UHD1, Q3UH36, Q8CGM0	Gene names	Bai1
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1 precursor.

BAI2_MOUSE
NC score	0.255192 (rank : 46)	θ value	0.0148317 (rank : 20)
Query Neighborhood Hits	93	Target Neighborhood Hits	323	Shared Neighborhood Hits	63
SwissProt Accessions	Q8CGM1, Q3TYC8, Q3UN11, Q3UNE2, Q6PGN0	Gene names	Bai2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 2 precursor.

BAI2_HUMAN
NC score	0.254170 (rank : 47)	θ value	0.0148317 (rank : 19)
Query Neighborhood Hits	93	Target Neighborhood Hits	332	Shared Neighborhood Hits	64
SwissProt Accessions	O60241, Q5T6K0, Q8NGW8	Gene names	BAI2
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 2 precursor.

GLP2R_HUMAN
NC score	0.250002 (rank : 48)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	93	Target Neighborhood Hits	75	Shared Neighborhood Hits	42
SwissProt Accessions	O95838	Gene names	GLP2R
Domain Architecture
Description	Glucagon-like peptide 2 receptor precursor (GLP-2 receptor) (GLP-2-R) (GLP-2R).

GP110_MOUSE
NC score	0.246292 (rank : 49)	θ value	1.38821 (rank : 66)
Query Neighborhood Hits	93	Target Neighborhood Hits	92	Shared Neighborhood Hits	40
SwissProt Accessions	Q8VEC3, Q8BMV8	Gene names	Gpr110
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 110 precursor.

LPHN1_HUMAN
NC score	0.244969 (rank : 50)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	93	Target Neighborhood Hits	155	Shared Neighborhood Hits	47
SwissProt Accessions	O94910, Q96IE7, Q9BU07, Q9HAR3	Gene names	LPHN1, KIAA0821, LEC2
Domain Architecture
Description	Latrophilin-1 precursor (Calcium-independent alpha-latrotoxin receptor 1) (Lectomedin-2).

LPHN2_HUMAN
NC score	0.240298 (rank : 51)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	93	Target Neighborhood Hits	136	Shared Neighborhood Hits	50
SwissProt Accessions	O95490, O94882, Q5VX76, Q9UKY5, Q9UKY6	Gene names	LPHN2, KIAA0786, LEC1, LPHH1
Domain Architecture
Description	Latrophilin-2 precursor (Calcium-independent alpha-latrotoxin receptor 2) (Latrophilin homolog 1) (Lectomedin-1).

CD97_MOUSE
NC score	0.240221 (rank : 52)	θ value	0.0113563 (rank : 18)
Query Neighborhood Hits	93	Target Neighborhood Hits	295	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

GP110_HUMAN
NC score	0.238873 (rank : 53)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	93	Target Neighborhood Hits	87	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T601, Q5KU15, Q5T5Z9, Q86SM1, Q8IXE3, Q8IZF8, Q96DQ1	Gene names	GPR110, PGR19
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 110 precursor (G-protein coupled receptor PGR19) (G-protein coupled receptor KPG_012).

ELTD1_HUMAN
NC score	0.234383 (rank : 54)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	93	Target Neighborhood Hits	269	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

GPR56_HUMAN
NC score	0.231461 (rank : 55)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	93	Target Neighborhood Hits	84	Shared Neighborhood Hits	46
SwissProt Accessions	Q9Y653, O95966, Q8NGB3, Q96HB4	Gene names	GPR56, TM7LN4, TM7XN1
Domain Architecture
Description	G-protein coupled receptor 56 precursor (TM7XN1 protein).

GP126_HUMAN
NC score	0.230634 (rank : 56)	θ value	1.06291 (rank : 62)
Query Neighborhood Hits	93	Target Neighborhood Hits	187	Shared Neighborhood Hits	60
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

GPR97_HUMAN
NC score	0.228670 (rank : 57)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	93	Target Neighborhood Hits	86	Shared Neighborhood Hits	44
SwissProt Accessions	Q86Y34, Q6ZMF4, Q86SL9, Q8IZF1	Gene names	GPR97, PGR26
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 97 precursor (G-protein coupled receptor PGR26).

BAI3_HUMAN
NC score	0.225175 (rank : 58)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	93	Target Neighborhood Hits	246	Shared Neighborhood Hits	56
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

BAI3_MOUSE
NC score	0.224980 (rank : 59)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	93	Target Neighborhood Hits	250	Shared Neighborhood Hits	56
SwissProt Accessions	Q80ZF8	Gene names	Bai3
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

GP116_HUMAN
NC score	0.224593 (rank : 60)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	93	Target Neighborhood Hits	167	Shared Neighborhood Hits	41
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GP114_HUMAN
NC score	0.218545 (rank : 61)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	93	Target Neighborhood Hits	75	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IZF4, Q6ZMH7, Q6ZML4, Q86SL8, Q8IZ14	Gene names	GPR114, PGR27
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 114 precursor (G-protein coupled receptor PGR27).

CD97_HUMAN
NC score	0.216974 (rank : 62)	θ value	0.0330416 (rank : 23)
Query Neighborhood Hits	93	Target Neighborhood Hits	353	Shared Neighborhood Hits	50
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

GPR56_MOUSE
NC score	0.213237 (rank : 63)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	93	Target Neighborhood Hits	89	Shared Neighborhood Hits	45
SwissProt Accessions	Q8K209, Q3UR17, Q9QZT2	Gene names	Gpr56, Cyt28
Domain Architecture
Description	G-protein coupled receptor 56 precursor (Serpentine receptor cyt28).

ELTD1_MOUSE
NC score	0.208043 (rank : 64)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	93	Target Neighborhood Hits	288	Shared Neighborhood Hits	48
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

GP111_HUMAN
NC score	0.206204 (rank : 65)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	93	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q8IZF7, Q86SL6, Q8NGU5, Q8TDT5	Gene names	GPR111, PGR20
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 111 (G-protein coupled receptor PGR20).

FZD3_HUMAN
NC score	0.202875 (rank : 66)	θ value	0.0736092 (rank : 32)
Query Neighborhood Hits	93	Target Neighborhood Hits	74	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NPG1	Gene names	FZD3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (hFz3).

FZD3_MOUSE
NC score	0.201628 (rank : 67)	θ value	0.0961366 (rank : 34)
Query Neighborhood Hits	93	Target Neighborhood Hits	75	Shared Neighborhood Hits	34
SwissProt Accessions	Q61086	Gene names	Fzd3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (mFz3).

FZD6_HUMAN
NC score	0.197003 (rank : 68)	θ value	0.279714 (rank : 50)
Query Neighborhood Hits	93	Target Neighborhood Hits	84	Shared Neighborhood Hits	36
SwissProt Accessions	O60353, Q6P9C3	Gene names	FZD6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (hFz6).

CELR1_HUMAN
NC score	0.193552 (rank : 69)	θ value	6.43352e-06 (rank : 3)
Query Neighborhood Hits	93	Target Neighborhood Hits	613	Shared Neighborhood Hits	59
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR1_MOUSE
NC score	0.190134 (rank : 70)	θ value	3.19293e-05 (rank : 5)
Query Neighborhood Hits	93	Target Neighborhood Hits	617	Shared Neighborhood Hits	64
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

EMR1_MOUSE
NC score	0.190099 (rank : 71)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	93	Target Neighborhood Hits	349	Shared Neighborhood Hits	50
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

EMR2_HUMAN
NC score	0.188997 (rank : 72)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	93	Target Neighborhood Hits	345	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

FZD6_MOUSE
NC score	0.186037 (rank : 73)	θ value	1.38821 (rank : 65)
Query Neighborhood Hits	93	Target Neighborhood Hits	135	Shared Neighborhood Hits	35
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

FZD1_MOUSE
NC score	0.185496 (rank : 74)	θ value	0.365318 (rank : 54)
Query Neighborhood Hits	93	Target Neighborhood Hits	63	Shared Neighborhood Hits	35
SwissProt Accessions	O70421, O08974	Gene names	Fzd1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (mFz1).

FZD9_MOUSE
NC score	0.185410 (rank : 75)	θ value	0.163984 (rank : 37)
Query Neighborhood Hits	93	Target Neighborhood Hits	66	Shared Neighborhood Hits	35
SwissProt Accessions	Q9R216, O35494, Q9CX16, Q9R2B3	Gene names	Fzd9, Fzd3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (mFz9) (mFz3).

FZD1_HUMAN
NC score	0.184910 (rank : 76)	θ value	0.279714 (rank : 49)
Query Neighborhood Hits	93	Target Neighborhood Hits	62	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UP38, O94815, Q549T8	Gene names	FZD1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (hFz1) (FzE1).

FZD2_MOUSE
NC score	0.183903 (rank : 77)	θ value	0.21417 (rank : 44)
Query Neighborhood Hits	93	Target Neighborhood Hits	60	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JIP6, Q810M0, Q9JIP5, Q9WUJ2	Gene names	Fzd2, Fzd10
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (mFz2) (mFz10).

FZD2_HUMAN
NC score	0.183866 (rank : 78)	θ value	0.21417 (rank : 43)
Query Neighborhood Hits	93	Target Neighborhood Hits	57	Shared Neighborhood Hits	32
SwissProt Accessions	Q14332	Gene names	FZD2
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (hFz2) (FzE2).

FZD7_MOUSE
NC score	0.183792 (rank : 79)	θ value	0.21417 (rank : 45)
Query Neighborhood Hits	93	Target Neighborhood Hits	59	Shared Neighborhood Hits	32
SwissProt Accessions	Q61090	Gene names	Fzd7
Domain Architecture	No domain graphic available
Description	Frizzled-7 precursor (Fz-7) (mFz7).

FZD9_HUMAN
NC score	0.183763 (rank : 80)	θ value	0.21417 (rank : 46)
Query Neighborhood Hits	93	Target Neighborhood Hits	63	Shared Neighborhood Hits	34
SwissProt Accessions	O00144	Gene names	FZD9, FZD3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (hFz9) (FzE6).

FZD7_HUMAN
NC score	0.181946 (rank : 81)	θ value	0.279714 (rank : 51)
Query Neighborhood Hits	93	Target Neighborhood Hits	56	Shared Neighborhood Hits	32
SwissProt Accessions	O75084, O94816, Q96B74	Gene names	FZD7
Domain Architecture
Description	Frizzled-7 precursor (Fz-7) (hFz7) (FzE3).

EMR1_HUMAN
NC score	0.180961 (rank : 82)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	93	Target Neighborhood Hits	382	Shared Neighborhood Hits	51
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

CELR2_MOUSE
NC score	0.180386 (rank : 83)	θ value	0.00134147 (rank : 8)
Query Neighborhood Hits	93	Target Neighborhood Hits	584	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

FZD8_HUMAN
NC score	0.178615 (rank : 84)	θ value	0.365318 (rank : 55)
Query Neighborhood Hits	93	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H461	Gene names	FZD8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (hFz8).

FZD8_MOUSE
NC score	0.178295 (rank : 85)	θ value	0.365318 (rank : 56)
Query Neighborhood Hits	93	Target Neighborhood Hits	89	Shared Neighborhood Hits	31
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

CELR2_HUMAN
NC score	0.175894 (rank : 86)	θ value	0.000461057 (rank : 7)
Query Neighborhood Hits	93	Target Neighborhood Hits	657	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR3_MOUSE
NC score	0.173059 (rank : 87)	θ value	0.0148317 (rank : 21)
Query Neighborhood Hits	93	Target Neighborhood Hits	687	Shared Neighborhood Hits	63
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

CELR3_HUMAN
NC score	0.170616 (rank : 88)	θ value	0.0330416 (rank : 24)
Query Neighborhood Hits	93	Target Neighborhood Hits	680	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

SMO_MOUSE
NC score	0.169545 (rank : 89)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	93	Target Neighborhood Hits	61	Shared Neighborhood Hits	27
SwissProt Accessions	P56726	Gene names	Smo, Smoh
Domain Architecture	No domain graphic available
Description	Smoothened homolog precursor (SMO).

SMO_HUMAN
NC score	0.168926 (rank : 90)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	93	Target Neighborhood Hits	61	Shared Neighborhood Hits	27
SwissProt Accessions	Q99835	Gene names	SMO, SMOH
Domain Architecture
Description	Smoothened homolog precursor (SMO) (Gx protein).

FZD10_HUMAN
NC score	0.168159 (rank : 91)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	93	Target Neighborhood Hits	51	Shared Neighborhood Hits	27
SwissProt Accessions	Q9ULW2	Gene names	FZD10
Domain Architecture
Description	Frizzled-10 precursor (Fz-10) (hFz10) (FzE7).

FZD10_MOUSE
NC score	0.168091 (rank : 92)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	93	Target Neighborhood Hits	56	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BKG4	Gene names	Fzd10, Fz10
Domain Architecture	No domain graphic available
Description	Frizzled-10 precursor (Fz-10).

FZD5_HUMAN
NC score	0.166271 (rank : 93)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	93	Target Neighborhood Hits	71	Shared Neighborhood Hits	31
SwissProt Accessions	Q13467, Q53R22	Gene names	FZD5, HFZ5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (hFz5) (FzE5).

FZD5_MOUSE
NC score	0.162679 (rank : 94)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	93	Target Neighborhood Hits	70	Shared Neighborhood Hits	31
SwissProt Accessions	Q9EQD0, O08975, Q8BMR2, Q8CHK9	Gene names	Fzd5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (mFz5).

FZD4_MOUSE
NC score	0.161681 (rank : 95)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	93	Target Neighborhood Hits	52	Shared Neighborhood Hits	28
SwissProt Accessions	Q61088	Gene names	Fzd4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (mFz4).

FZD4_HUMAN
NC score	0.161474 (rank : 96)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	93	Target Neighborhood Hits	54	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ULV1, Q6S9E4	Gene names	FZD4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (hFz4) (FzE4).

GPR98_HUMAN
NC score	0.161343 (rank : 97)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	93	Target Neighborhood Hits	202	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

GPR98_MOUSE
NC score	0.147643 (rank : 98)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	93	Target Neighborhood Hits	206	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

GP123_HUMAN
NC score	0.140618 (rank : 99)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	93	Target Neighborhood Hits	120	Shared Neighborhood Hits	25
SwissProt Accessions	Q86SQ6, Q86SN7, Q96JJ9	Gene names	GPR123, KIAA1828
Domain Architecture
Description	Probable G-protein coupled receptor 123.

SFRP4_HUMAN
NC score	0.115655 (rank : 100)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	93	Target Neighborhood Hits	43	Shared Neighborhood Hits	21
SwissProt Accessions	Q6FHJ7, O14877, Q4G124, Q6FHM0, Q6PD64	Gene names	SFRP4, FRPHE
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 4 precursor (sFRP-4) (Frizzled protein, human endometrium) (FrpHE).

SFRP4_MOUSE
NC score	0.115522 (rank : 101)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	93	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z1N6, Q91ZX9	Gene names	Sfrp4
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related sequence protein 4 precursor (sFRP-4) (Frizzled-related protein 4) (FRP-4).

SFRP3_MOUSE
NC score	0.113007 (rank : 102)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	93	Target Neighborhood Hits	44	Shared Neighborhood Hits	21
SwissProt Accessions	P97401, O09075, O09093, Q91W58	Gene names	Frzb, Fiz, Fre, Frzb1, Sfrp3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP3_HUMAN
NC score	0.112793 (rank : 103)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	93	Target Neighborhood Hits	43	Shared Neighborhood Hits	21
SwissProt Accessions	Q92765, O00181, Q99686	Gene names	FRZB, FIZ, FRE, FRP, FRZB1, SFRP3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP5_MOUSE
NC score	0.106147 (rank : 104)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	93	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WU66, Q8K269	Gene names	Sfrp5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5).

SFRP5_HUMAN
NC score	0.106064 (rank : 105)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	93	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q5T4F7, O14780, Q86TH7	Gene names	SFRP5, FRP1B, SARP3
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5) (Secreted apoptosis-related protein 3) (SARP-3) (Frizzled-related protein 1b) (FRP-1b).

SFRP1_MOUSE
NC score	0.105674 (rank : 106)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	93	Target Neighborhood Hits	43	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C4U3, O08861, Q8R1J4	Gene names	Sfrp1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1).

SFRP2_MOUSE
NC score	0.105477 (rank : 107)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	93	Target Neighborhood Hits	47	Shared Neighborhood Hits	19
SwissProt Accessions	P97299, O08862, O35297	Gene names	Sfrp2, Sarp1, Sdf5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (SDF5 protein).

SFRP1_HUMAN
NC score	0.105410 (rank : 108)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	93	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	Q8N474, O00546, O14779	Gene names	SFRP1, FRP, FRP1, SARP2
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1) (Frizzled- related protein 1) (FRP-1) (Secreted apoptosis-related protein 2) (SARP-2).

SFRP2_HUMAN
NC score	0.105254 (rank : 109)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	93	Target Neighborhood Hits	46	Shared Neighborhood Hits	19
SwissProt Accessions	Q96HF1, O14778, Q9HAP5	Gene names	SFRP2, FRP2, SARP1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (Frizzled-related protein 2) (FRP-2).

GP124_MOUSE
NC score	0.095880 (rank : 110)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	93	Target Neighborhood Hits	423	Shared Neighborhood Hits	31
SwissProt Accessions	Q91ZV8	Gene names	Gpr124, Tem5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP125_HUMAN
NC score	0.094614 (rank : 111)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	93	Target Neighborhood Hits	327	Shared Neighborhood Hits	25
SwissProt Accessions	Q8IWK6, Q6UXK9, Q86SQ5, Q8TC55	Gene names	GPR125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

GP124_HUMAN
NC score	0.089142 (rank : 112)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	93	Target Neighborhood Hits	304	Shared Neighborhood Hits	26
SwissProt Accessions	Q96PE1, Q8N3R1, Q8TEM3, Q96KB2, Q9P1Z7, Q9UFY4	Gene names	GPR124, KIAA1531, TEM5
Domain Architecture
Description	Probable G-protein coupled receptor 124 precursor (Tumor endothelial marker 5).

GP125_MOUSE
NC score	0.088299 (rank : 113)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	93	Target Neighborhood Hits	329	Shared Neighborhood Hits	24
SwissProt Accessions	Q7TT36, Q6PE67, Q8VE71	Gene names	Gpr125
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 125 precursor.

MFRP_MOUSE
NC score	0.061693 (rank : 114)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	93	Target Neighborhood Hits	166	Shared Neighborhood Hits	22
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_HUMAN
NC score	0.060782 (rank : 115)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	93	Target Neighborhood Hits	165	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CAD23_MOUSE
NC score	0.058630 (rank : 116)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	93	Target Neighborhood Hits	208	Shared Neighborhood Hits	7
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

CAD23_HUMAN
NC score	0.058549 (rank : 117)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	93	Target Neighborhood Hits	197	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H251, Q6UWW1, Q9H4K9	Gene names	CDH23, KIAA1774
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

PCD15_MOUSE
NC score	0.058298 (rank : 118)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	93	Target Neighborhood Hits	262	Shared Neighborhood Hits	6
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

PCD15_HUMAN
NC score	0.058222 (rank : 119)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	93	Target Neighborhood Hits	289	Shared Neighborhood Hits	6
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

PCDLK_HUMAN
NC score	0.056445 (rank : 120)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	93	Target Neighborhood Hits	172	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYE9, Q9NXP8	Gene names	PCLKC
Domain Architecture	No domain graphic available
Description	Protocadherin LKC precursor (PC-LKC).

PCD16_HUMAN
NC score	0.056009 (rank : 121)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	93	Target Neighborhood Hits	245	Shared Neighborhood Hits	6
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

CBPZ_HUMAN
NC score	0.055461 (rank : 122)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	93	Target Neighborhood Hits	69	Shared Neighborhood Hits	21
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

FAT2_HUMAN
NC score	0.053890 (rank : 123)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	93	Target Neighborhood Hits	507	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

CRUM1_MOUSE
NC score	0.053230 (rank : 124)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	93	Target Neighborhood Hits	444	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

FATH_HUMAN
NC score	0.052799 (rank : 125)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	93	Target Neighborhood Hits	570	Shared Neighborhood Hits	10
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

GP155_HUMAN
NC score	0.052502 (rank : 126)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	93	Target Neighborhood Hits	42	Shared Neighborhood Hits	21
SwissProt Accessions	Q7Z3F1, Q53SJ3, Q53TA8, Q69YG8, Q86SP9, Q8N261, Q8N639, Q8N8K3, Q96MV6	Gene names	GPR155, PGR22
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR155 (G-protein coupled receptor PGR22).

CRUM1_HUMAN
NC score	0.052372 (rank : 127)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	93	Target Neighborhood Hits	457	Shared Neighborhood Hits	10
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CAD17_MOUSE
NC score	0.051598 (rank : 128)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	93	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R100	Gene names	Cdh17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (BILL- cadherin) (P130).

V1AR_MOUSE
NC score	0.051375 (rank : 129)	θ value	0.00665767 (rank : 15)
Query Neighborhood Hits	93	Target Neighborhood Hits	897	Shared Neighborhood Hits	19
SwissProt Accessions	Q62463, Q62464, Q9QYH2	Gene names	Avpr1a
Domain Architecture
Description	Vasopressin V1a receptor (V1aR) (Vascular/hepatic-type arginine vasopressin receptor) (Antidiuretic hormone receptor 1a) (AVPR V1a).

PCDH1_HUMAN
NC score	0.050430 (rank : 130)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	93	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	Q08174	Gene names	PCDH1
Domain Architecture
Description	Protocadherin-1 precursor (Protocadherin-42) (PC42) (Cadherin-like protein 1).

GP143_HUMAN
NC score	0.040104 (rank : 131)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	93	Target Neighborhood Hits	17	Shared Neighborhood Hits	7
SwissProt Accessions	P51810	Gene names	GPR143, OA1
Domain Architecture
Description	G-protein coupled receptor 143 (Ocular albinism type 1 protein).

MTR1L_HUMAN
NC score	0.039930 (rank : 132)	θ value	0.0330416 (rank : 26)
Query Neighborhood Hits	93	Target Neighborhood Hits	1180	Shared Neighborhood Hits	19
SwissProt Accessions	Q13585	Gene names	GPR50
Domain Architecture
Description	Melatonin-related receptor (G protein-coupled receptor 50) (H9).

EDG1_MOUSE
NC score	0.039347 (rank : 133)	θ value	0.0736092 (rank : 31)
Query Neighborhood Hits	93	Target Neighborhood Hits	867	Shared Neighborhood Hits	18
SwissProt Accessions	O08530, Q9R235	Gene names	Edg1, Lpb1
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-1 (Sphingosine 1-phosphate receptor 1) (S1P1) (Lysophospholipid receptor B1).

5HT1A_HUMAN
NC score	0.038884 (rank : 134)	θ value	0.0431538 (rank : 28)
Query Neighborhood Hits	93	Target Neighborhood Hits	887	Shared Neighborhood Hits	19
SwissProt Accessions	P08908, Q6LAE7	Gene names	HTR1A
Domain Architecture
Description	5-hydroxytryptamine 1A receptor (5-HT-1A) (Serotonin receptor 1A) (5- HT1A) (G-21).

V1AR_HUMAN
NC score	0.038552 (rank : 135)	θ value	1.06291 (rank : 63)
Query Neighborhood Hits	93	Target Neighborhood Hits	891	Shared Neighborhood Hits	18
SwissProt Accessions	P37288	Gene names	AVPR1A, AVPR1
Domain Architecture
Description	Vasopressin V1a receptor (V1aR) (Vascular/hepatic-type arginine vasopressin receptor) (Antidiuretic hormone receptor 1a) (AVPR V1a).

5HT1A_MOUSE
NC score	0.036839 (rank : 136)	θ value	0.21417 (rank : 41)
Query Neighborhood Hits	93	Target Neighborhood Hits	891	Shared Neighborhood Hits	19
SwissProt Accessions	Q64264, Q60956, Q61617	Gene names	Htr1a, Gpcr18
Domain Architecture
Description	5-hydroxytryptamine 1A receptor (5-HT-1A) (Serotonin receptor 1A) (5- HT1A).

EDG1_HUMAN
NC score	0.036627 (rank : 137)	θ value	0.62314 (rank : 58)
Query Neighborhood Hits	93	Target Neighborhood Hits	860	Shared Neighborhood Hits	18
SwissProt Accessions	P21453	Gene names	EDG1
Domain Architecture
Description	Sphingosine 1-phosphate receptor Edg-1 (Sphingosine 1-phosphate receptor 1) (S1P1).

5HT5A_MOUSE
NC score	0.036064 (rank : 138)	θ value	0.21417 (rank : 42)
Query Neighborhood Hits	93	Target Neighborhood Hits	615	Shared Neighborhood Hits	16
SwissProt Accessions	P30966	Gene names	Htr5a, 5ht5a
Domain Architecture
Description	5-hydroxytryptamine 5A receptor (5-HT-5A) (Serotonin receptor 5A) (5- HT-5).

GPR3_MOUSE
NC score	0.035542 (rank : 139)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	93	Target Neighborhood Hits	584	Shared Neighborhood Hits	15
SwissProt Accessions	P35413	Gene names	Gpr3, Gpcr3
Domain Architecture
Description	Probable G-protein coupled receptor 3 (GPCR21).

GPR3_HUMAN
NC score	0.034654 (rank : 140)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	93	Target Neighborhood Hits	578	Shared Neighborhood Hits	15
SwissProt Accessions	P46089	Gene names	GPR3, ACCA
Domain Architecture
Description	Probable G-protein coupled receptor 3 (ACCA orphan receptor).

GP143_MOUSE
NC score	0.030432 (rank : 141)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	93	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P70259, O89031	Gene names	Gpr143, Oa1
Domain Architecture
Description	G-protein coupled receptor 143 (Ocular albinism type 1 protein homolog) (MOA1).

CCR6_HUMAN
NC score	0.028463 (rank : 142)	θ value	0.365318 (rank : 53)
Query Neighborhood Hits	93	Target Neighborhood Hits	650	Shared Neighborhood Hits	16
SwissProt Accessions	P51684, P78553, Q92846	Gene names	CCR6, CKRL3, CMKBR6, GPR29, STRL22
Domain Architecture
Description	C-C chemokine receptor type 6 (C-C CKR-6) (CC-CKR-6) (CCR-6) (LARC receptor) (GPR-CY4) (GPRCY4) (Chemokine receptor-like 3) (CKR-L3) (DRY6) (G-protein coupled receptor 29) (CD196 antigen).

CXCR4_MOUSE
NC score	0.027315 (rank : 143)	θ value	0.62314 (rank : 57)
Query Neighborhood Hits	93	Target Neighborhood Hits	702	Shared Neighborhood Hits	16
SwissProt Accessions	P70658, O09059, O09062, P70233, P70346, Q4KMW1	Gene names	Cxcr4, Cmkar4, Lestr, Sdf1r
Domain Architecture
Description	C-X-C chemokine receptor type 4 (CXC-R4) (CXCR-4) (Stromal cell- derived factor 1 receptor) (SDF-1 receptor) (Fusin) (Leukocyte-derived seven transmembrane domain receptor) (LESTR) (Pre-B-cell-derived chemokine receptor) (PB-CKR) (CD184 antigen).

CXCR4_HUMAN
NC score	0.026984 (rank : 144)	θ value	0.279714 (rank : 48)
Query Neighborhood Hits	93	Target Neighborhood Hits	707	Shared Neighborhood Hits	16
SwissProt Accessions	P61073, O60835, P30991, P56438, Q9UKN2	Gene names	CXCR4
Domain Architecture
Description	C-X-C chemokine receptor type 4 (CXC-R4) (CXCR-4) (Stromal cell- derived factor 1 receptor) (SDF-1 receptor) (Fusin) (Leukocyte-derived seven transmembrane domain receptor) (LESTR) (LCR1) (FB22) (NPYRL) (HM89) (CD184 antigen).

CXCR5_MOUSE
NC score	0.025416 (rank : 145)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	93	Target Neighborhood Hits	705	Shared Neighborhood Hits	16
SwissProt Accessions	Q04683	Gene names	Blr1, Cxcr5, Gpcr6
Domain Architecture
Description	C-X-C chemokine receptor type 5 (CXC-R5) (CXCR-5) (Burkitt lymphoma receptor 1 homolog) (CD185 antigen).

CABL2_MOUSE
NC score	0.025253 (rank : 146)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	93	Target Neighborhood Hits	79	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K3M5	Gene names	Cables2
Domain Architecture
Description	CDK5 and ABL1 enzyme substrate 2 (Interactor with CDK3 2) (Ik3-2).

OPN3_MOUSE
NC score	0.024037 (rank : 147)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	93	Target Neighborhood Hits	782	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WUK7, Q3V0X3	Gene names	Opn3, Ecpn
Domain Architecture
Description	Opsin-3 (Encephalopsin) (Panopsin).

RECQ4_HUMAN
NC score	0.020874 (rank : 148)	θ value	1.81305 (rank : 71)
Query Neighborhood Hits	93	Target Neighborhood Hits	177	Shared Neighborhood Hits	2
SwissProt Accessions	O94761, Q3Y424, Q96DW2, Q96F55	Gene names	RECQL4, RECQ4
Domain Architecture
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4) (RecQ4) (RTS).

MALL_HUMAN
NC score	0.014059 (rank : 149)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	93	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q13021, Q9BTU0	Gene names	MALL, BENE
Domain Architecture
Description	MAL-like protein (Protein BENE).

CHST5_MOUSE
NC score	0.011690 (rank : 150)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	93	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QUP4	Gene names	Chst5, Gst4
Domain Architecture	No domain graphic available
Description	Carbohydrate sulfotransferase 5 (EC 2.8.2.-) (N-acetylglucosamine 6-O- sulfotransferase 3) (GlcNAc6ST-3) (Intestinal GlcNAc-6- sulfotransferase) (Intestinal N-acetylglucosamine-6-O- sulfotransferase) (I-GlcNAc6ST) (mIGn6ST) (Galactose/N- acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4) (GST4).

MLL2_HUMAN
NC score	0.005379 (rank : 151)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	93	Target Neighborhood Hits	1788	Shared Neighborhood Hits	11
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

OR6X1_HUMAN
NC score	0.002935 (rank : 152)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	93	Target Neighborhood Hits	771	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NH79, Q6IFA0	Gene names	OR6X1
Domain Architecture
Description	Olfactory receptor 6X1 (Olfactory receptor OR11-270).

OLF15_MOUSE
NC score	0.001018 (rank : 153)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	93	Target Neighborhood Hits	752	Shared Neighborhood Hits	11
SwissProt Accessions	P23275	Gene names	Olfr15
Domain Architecture
Description	Olfactory receptor 15 (Odorant receptor OR3).