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Network neighborhood for query Sequence : HTRA2_MOUSE

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HTRA2_MOUSE
 
SwissProt Accessions Q9JIY5, Q9R108 Gene names Htra2, Omi, Prss25
Domain
Architecture
Description Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).
Rank Plots



Hits sorted by θ


HTRA2_MOUSE
 
θ value 0 (rank : 1) NC score 0.999962 (rank : 1)
Query Neighborhood Hits 29 Target Neighborhood Hits 29 Shared Neighborhood Hits 29
SwissProt Accessions Q9JIY5, Q9R108 Gene names Htra2, Omi, Prss25
Domain
Architecture
Description Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).
HTRA2_HUMAN
 
θ value 7.71569e-185 (rank : 2) NC score 0.997314 (rank : 2)
Query Neighborhood Hits 29 Target Neighborhood Hits 30 Shared Neighborhood Hits 22
SwissProt Accessions O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4 Gene names HTRA2, OMI, PRSS25
Domain
Architecture
Description Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).
HTRA3_HUMAN
 
θ value 4.06505e-93 (rank : 3) NC score 0.908186 (rank : 4)
Query Neighborhood Hits 29 Target Neighborhood Hits 152 Shared Neighborhood Hits 19
SwissProt Accessions P83110, Q7Z7A2 Gene names HTRA3, PRSP
Domain
Architecture
Description Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).
HTRA3_MOUSE
 
θ value 5.86991e-92 (rank : 4) NC score 0.904267 (rank : 5)
Query Neighborhood Hits 29 Target Neighborhood Hits 156 Shared Neighborhood Hits 20
SwissProt Accessions Q9D236, Q6WLC5, Q6YDR0 Gene names Htra3, Prsp, Tasp
Domain
Architecture
Description Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).
HTRA1_HUMAN
 
θ value 8.47616e-91 (rank : 5) NC score 0.869951 (rank : 7)
Query Neighborhood Hits 29 Target Neighborhood Hits 155 Shared Neighborhood Hits 16
SwissProt Accessions Q92743, Q9UNS5 Gene names HTRA1, HTRA, PRSS11
Domain
Architecture
Description Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).
HTRA1_MOUSE
 
θ value 1.03614e-88 (rank : 6) NC score 0.873310 (rank : 6)
Query Neighborhood Hits 29 Target Neighborhood Hits 140 Shared Neighborhood Hits 15
SwissProt Accessions Q9R118 Gene names Htra1, Htra, Prss11
Domain
Architecture
Description Serine protease HTRA1 precursor (EC 3.4.21.-).
HTRA4_HUMAN
 
θ value 6.73165e-80 (rank : 7) NC score 0.911642 (rank : 3)
Query Neighborhood Hits 29 Target Neighborhood Hits 119 Shared Neighborhood Hits 12
SwissProt Accessions P83105, Q542Z4, Q6PF13 Gene names HTRA4
Domain
Architecture

No domain graphic available

Description Probable serine protease HTRA4 precursor (EC 3.4.21.-).
PDZ11_HUMAN
 
θ value 0.00102713 (rank : 8) NC score 0.149503 (rank : 18)
Query Neighborhood Hits 29 Target Neighborhood Hits 160 Shared Neighborhood Hits 24
SwissProt Accessions Q5EBL8, Q6UWE1, Q9P0Q1 Gene names PDZD11, PDZK11
Domain
Architecture

No domain graphic available

Description PDZ domain-containing protein 11.
PDZ11_MOUSE
 
θ value 0.00102713 (rank : 9) NC score 0.147660 (rank : 19)
Query Neighborhood Hits 29 Target Neighborhood Hits 154 Shared Neighborhood Hits 23
SwissProt Accessions Q9CZG9 Gene names Pdzd11, Pdzk11
Domain
Architecture

No domain graphic available

Description PDZ domain-containing protein 11.
PDLI3_HUMAN
 
θ value 0.813845 (rank : 10) NC score 0.044068 (rank : 65)
Query Neighborhood Hits 29 Target Neighborhood Hits 199 Shared Neighborhood Hits 15
SwissProt Accessions Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4 Gene names PDLIM3, ALP
Domain
Architecture

No domain graphic available

Description PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).
PDZD1_HUMAN
 
θ value 1.38821 (rank : 11) NC score 0.097524 (rank : 27)
Query Neighborhood Hits 29 Target Neighborhood Hits 190 Shared Neighborhood Hits 23
SwissProt Accessions Q5T2W1, O60450, Q5T5P6, Q9BQ41 Gene names PDZK1, CAP70, NHERF3, PDZD1
Domain
Architecture

No domain graphic available

Description PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).
DLG5_HUMAN
 
θ value 1.81305 (rank : 12) NC score 0.028408 (rank : 74)
Query Neighborhood Hits 29 Target Neighborhood Hits 1088 Shared Neighborhood Hits 19
SwissProt Accessions Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3 Gene names DLG5, KIAA0583, PDLG
Domain
Architecture
Description Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).
LAP4_MOUSE
 
θ value 1.81305 (rank : 13) NC score 0.036730 (rank : 70)
Query Neighborhood Hits 29 Target Neighborhood Hits 590 Shared Neighborhood Hits 25
SwissProt Accessions Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3 Gene names Scrib, Kiaa0147, Lap4, Scrib1
Domain
Architecture

No domain graphic available

Description Protein LAP4 (Protein scribble homolog).
PARP6_HUMAN
 
θ value 1.81305 (rank : 14) NC score 0.028501 (rank : 72)
Query Neighborhood Hits 29 Target Neighborhood Hits 16 Shared Neighborhood Hits 3
SwissProt Accessions Q2NL67, Q9H7C5, Q9H9X6, Q9HAF3, Q9NPS6, Q9UFG4 Gene names PARP6
Domain
Architecture

No domain graphic available

Description Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).
PARP6_MOUSE
 
θ value 1.81305 (rank : 15) NC score 0.028496 (rank : 73)
Query Neighborhood Hits 29 Target Neighborhood Hits 17 Shared Neighborhood Hits 3
SwissProt Accessions Q6P6P7, Q8BVW1 Gene names Parp6
Domain
Architecture

No domain graphic available

Description Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).
PDZD1_MOUSE
 
θ value 1.81305 (rank : 16) NC score 0.096464 (rank : 28)
Query Neighborhood Hits 29 Target Neighborhood Hits 191 Shared Neighborhood Hits 24
SwissProt Accessions Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72 Gene names Pdzk1, Cap70, Nherf3
Domain
Architecture

No domain graphic available

Description PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).
LAP4_HUMAN
 
θ value 2.36792 (rank : 17) NC score 0.041356 (rank : 67)
Query Neighborhood Hits 29 Target Neighborhood Hits 608 Shared Neighborhood Hits 25
SwissProt Accessions Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1 Gene names SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain
Architecture

No domain graphic available

Description Protein LAP4 (Protein scribble homolog) (hScrib).
PDLI3_MOUSE
 
θ value 2.36792 (rank : 18) NC score 0.038024 (rank : 69)
Query Neighborhood Hits 29 Target Neighborhood Hits 197 Shared Neighborhood Hits 15
SwissProt Accessions O70209 Gene names Pdlim3
Domain
Architecture

No domain graphic available

Description PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).
GRIP2_HUMAN
 
θ value 3.0926 (rank : 19) NC score 0.044051 (rank : 66)
Query Neighborhood Hits 29 Target Neighborhood Hits 256 Shared Neighborhood Hits 22
SwissProt Accessions Q9C0E4, Q8TEH9, Q9H7H3 Gene names GRIP2, KIAA1719
Domain
Architecture
Description Glutamate receptor-interacting protein 2 (GRIP2 protein).
PDLI2_MOUSE
 
θ value 4.03905 (rank : 20) NC score 0.041172 (rank : 68)
Query Neighborhood Hits 29 Target Neighborhood Hits 220 Shared Neighborhood Hits 17
SwissProt Accessions Q8R1G6 Gene names Pdlim2
Domain
Architecture

No domain graphic available

Description PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).
SDCB1_HUMAN
 
θ value 4.03905 (rank : 21) NC score 0.057227 (rank : 55)
Query Neighborhood Hits 29 Target Neighborhood Hits 150 Shared Neighborhood Hits 17
SwissProt Accessions O00560, O00173, O43391 Gene names SDCBP, MDA9, SYCL
Domain
Architecture
Description Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).
ZN133_HUMAN
 
θ value 4.03905 (rank : 22) NC score -0.001030 (rank : 78)
Query Neighborhood Hits 29 Target Neighborhood Hits 784 Shared Neighborhood Hits 3
SwissProt Accessions P52736, Q9BUV2, Q9H443 Gene names ZNF133
Domain
Architecture
Description Zinc finger protein 133.
NHERF_HUMAN
 
θ value 5.27518 (rank : 23) NC score 0.073313 (rank : 45)
Query Neighborhood Hits 29 Target Neighborhood Hits 190 Shared Neighborhood Hits 23
SwissProt Accessions O14745, O43552, Q86WQ5 Gene names SLC9A3R1, NHERF
Domain
Architecture
Description Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).
RGS12_HUMAN
 
θ value 5.27518 (rank : 24) NC score 0.024669 (rank : 75)
Query Neighborhood Hits 29 Target Neighborhood Hits 333 Shared Neighborhood Hits 19
SwissProt Accessions O14924, O14922, O14923, O43510, O75338 Gene names RGS12
Domain
Architecture
Description Regulator of G-protein signaling 12 (RGS12).
SDCB1_MOUSE
 
θ value 5.27518 (rank : 25) NC score 0.053744 (rank : 58)
Query Neighborhood Hits 29 Target Neighborhood Hits 144 Shared Neighborhood Hits 17
SwissProt Accessions O08992, Q544P5 Gene names Sdcbp
Domain
Architecture
Description Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).
SHAN1_HUMAN
 
θ value 5.27518 (rank : 26) NC score 0.014919 (rank : 77)
Query Neighborhood Hits 29 Target Neighborhood Hits 1041 Shared Neighborhood Hits 19
SwissProt Accessions Q9Y566, Q9NYW9 Gene names SHANK1
Domain
Architecture
Description SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).
CREG2_HUMAN
 
θ value 8.99809 (rank : 27) NC score 0.015628 (rank : 76)
Query Neighborhood Hits 29 Target Neighborhood Hits 11 Shared Neighborhood Hits 3
SwissProt Accessions Q8IUH2, Q86X03, Q8N540, Q8N9E3 Gene names CREG2
Domain
Architecture

No domain graphic available

Description Protein CREG2 precursor.
NHERF_MOUSE
 
θ value 8.99809 (rank : 28) NC score 0.070215 (rank : 46)
Query Neighborhood Hits 29 Target Neighborhood Hits 195 Shared Neighborhood Hits 23
SwissProt Accessions P70441 Gene names Slc9a3r1, Nherf
Domain
Architecture
Description Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).
PDLI2_HUMAN
 
θ value 8.99809 (rank : 29) NC score 0.031905 (rank : 71)
Query Neighborhood Hits 29 Target Neighborhood Hits 245 Shared Neighborhood Hits 16
SwissProt Accessions Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2 Gene names PDLIM2
Domain
Architecture

No domain graphic available

Description PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).
CRIM1_HUMAN
 
θ value θ > 10 (rank : 30) NC score 0.079366 (rank : 38)
Query Neighborhood Hits 29 Target Neighborhood Hits 362 Shared Neighborhood Hits 5
SwissProt Accessions Q9NZV1, Q59GH0, Q7LCQ5, Q9H318 Gene names CRIM1
Domain
Architecture

No domain graphic available

Description Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).
CTGF_HUMAN
 
θ value θ > 10 (rank : 31) NC score 0.076413 (rank : 40)
Query Neighborhood Hits 29 Target Neighborhood Hits 128 Shared Neighborhood Hits 5
SwissProt Accessions P29279, Q96QX2 Gene names CTGF, CCN2, HCS24
Domain
Architecture
Description Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).
CTGF_MOUSE
 
θ value θ > 10 (rank : 32) NC score 0.054970 (rank : 56)
Query Neighborhood Hits 29 Target Neighborhood Hits 124 Shared Neighborhood Hits 5
SwissProt Accessions P29268, Q922U0 Gene names Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain
Architecture
Description Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).
CYR61_HUMAN
 
θ value θ > 10 (rank : 33) NC score 0.090041 (rank : 31)
Query Neighborhood Hits 29 Target Neighborhood Hits 159 Shared Neighborhood Hits 5
SwissProt Accessions O00622, O14934, O43775, Q9BZL7 Gene names CYR61, CCN1, GIG1, IGFBP10
Domain
Architecture
Description Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).
CYR61_MOUSE
 
θ value θ > 10 (rank : 34) NC score 0.090206 (rank : 30)
Query Neighborhood Hits 29 Target Neighborhood Hits 156 Shared Neighborhood Hits 5
SwissProt Accessions P18406 Gene names Cyr61, Ccn1, Igfbp10
Domain
Architecture
Description Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).
ESM1_HUMAN
 
θ value θ > 10 (rank : 35) NC score 0.195688 (rank : 17)
Query Neighborhood Hits 29 Target Neighborhood Hits 110 Shared Neighborhood Hits 5
SwissProt Accessions Q9NQ30, Q15330, Q96ES3 Gene names ESM1
Domain
Architecture

No domain graphic available

Description Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).
ESM1_MOUSE
 
θ value θ > 10 (rank : 36) NC score 0.200624 (rank : 16)
Query Neighborhood Hits 29 Target Neighborhood Hits 107 Shared Neighborhood Hits 5
SwissProt Accessions Q9QYY7 Gene names Esm1
Domain
Architecture
Description Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).
FSTL3_HUMAN
 
θ value θ > 10 (rank : 37) NC score 0.051772 (rank : 59)
Query Neighborhood Hits 29 Target Neighborhood Hits 162 Shared Neighborhood Hits 5
SwissProt Accessions O95633 Gene names FSTL3, FLRG
Domain
Architecture
Description Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).
FSTL3_MOUSE
 
θ value θ > 10 (rank : 38) NC score 0.050395 (rank : 62)
Query Neighborhood Hits 29 Target Neighborhood Hits 152 Shared Neighborhood Hits 5
SwissProt Accessions Q9EQC7 Gene names Fstl3, Flrg
Domain
Architecture
Description Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).
IBP1_HUMAN
 
θ value θ > 10 (rank : 39) NC score 0.058195 (rank : 53)
Query Neighborhood Hits 29 Target Neighborhood Hits 67 Shared Neighborhood Hits 2
SwissProt Accessions P08833, Q8IYP5 Gene names IGFBP1, IBP1
Domain
Architecture
Description Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).
IBP1_MOUSE
 
θ value θ > 10 (rank : 40) NC score 0.094675 (rank : 29)
Query Neighborhood Hits 29 Target Neighborhood Hits 97 Shared Neighborhood Hits 5
SwissProt Accessions P47876, Q61732 Gene names Igfbp1, Igfbp-1
Domain
Architecture
Description Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).
IBP2_HUMAN
 
θ value θ > 10 (rank : 41) NC score 0.085589 (rank : 34)
Query Neighborhood Hits 29 Target Neighborhood Hits 61 Shared Neighborhood Hits 5
SwissProt Accessions P18065, Q14619, Q9UCL3 Gene names IGFBP2, BP2
Domain
Architecture
Description Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).
IBP2_MOUSE
 
θ value θ > 10 (rank : 42) NC score 0.073374 (rank : 44)
Query Neighborhood Hits 29 Target Neighborhood Hits 65 Shared Neighborhood Hits 5
SwissProt Accessions P47877, Q61722 Gene names Igfbp2, Igfbp-2
Domain
Architecture
Description Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).
IBP3_HUMAN
 
θ value θ > 10 (rank : 43) NC score 0.109939 (rank : 23)
Query Neighborhood Hits 29 Target Neighborhood Hits 67 Shared Neighborhood Hits 5
SwissProt Accessions P17936, Q2V509, Q6P1M6 Gene names IGFBP3, IBP3
Domain
Architecture
Description Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).
IBP3_MOUSE
 
θ value θ > 10 (rank : 44) NC score 0.078777 (rank : 39)
Query Neighborhood Hits 29 Target Neighborhood Hits 60 Shared Neighborhood Hits 5
SwissProt Accessions P47878 Gene names Igfbp3, Igfbp-3
Domain
Architecture
Description Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).
IBP4_HUMAN
 
θ value θ > 10 (rank : 45) NC score 0.068540 (rank : 48)
Query Neighborhood Hits 29 Target Neighborhood Hits 52 Shared Neighborhood Hits 4
SwissProt Accessions P22692 Gene names IGFBP4, IBP4
Domain
Architecture
Description Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).
IBP4_MOUSE
 
θ value θ > 10 (rank : 46) NC score 0.064559 (rank : 51)
Query Neighborhood Hits 29 Target Neighborhood Hits 55 Shared Neighborhood Hits 4
SwissProt Accessions P47879, O35666 Gene names Igfbp4, Igfbp-4
Domain
Architecture
Description Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).
IBP5_HUMAN
 
θ value θ > 10 (rank : 47) NC score 0.081927 (rank : 37)
Query Neighborhood Hits 29 Target Neighborhood Hits 68 Shared Neighborhood Hits 5
SwissProt Accessions P24593 Gene names IGFBP5, IBP5
Domain
Architecture
Description Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).
IBP5_MOUSE
 
θ value θ > 10 (rank : 48) NC score 0.082069 (rank : 36)
Query Neighborhood Hits 29 Target Neighborhood Hits 68 Shared Neighborhood Hits 5
SwissProt Accessions Q07079 Gene names Igfbp5, Igfbp-5
Domain
Architecture
Description Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).
IBP7_HUMAN
 
θ value θ > 10 (rank : 49) NC score 0.267673 (rank : 9)
Query Neighborhood Hits 29 Target Neighborhood Hits 220 Shared Neighborhood Hits 5
SwissProt Accessions Q16270, Q07822 Gene names IGFBP7, MAC25, PSF
Domain
Architecture
Description Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).
IBP7_MOUSE
 
θ value θ > 10 (rank : 50) NC score 0.261008 (rank : 10)
Query Neighborhood Hits 29 Target Neighborhood Hits 230 Shared Neighborhood Hits 5
SwissProt Accessions Q61581, O88812, Q9EQW0 Gene names Igfbp7, Mac25
Domain
Architecture
Description Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).
IPK1_HUMAN
 
θ value θ > 10 (rank : 51) NC score 0.070042 (rank : 47)
Query Neighborhood Hits 29 Target Neighborhood Hits 38 Shared Neighborhood Hits 4
SwissProt Accessions P00995 Gene names SPINK1, PSTI
Domain
Architecture
Description Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).
ISK3_MOUSE
 
θ value θ > 10 (rank : 52) NC score 0.100547 (rank : 26)
Query Neighborhood Hits 29 Target Neighborhood Hits 36 Shared Neighborhood Hits 5
SwissProt Accessions P09036, Q5M9M3 Gene names Spink3
Domain
Architecture
Description Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).
KAZD1_HUMAN
 
θ value θ > 10 (rank : 53) NC score 0.211756 (rank : 14)
Query Neighborhood Hits 29 Target Neighborhood Hits 248 Shared Neighborhood Hits 5
SwissProt Accessions Q96I82, Q6ZMB1, Q9BQ73 Gene names KAZALD1
Domain
Architecture

No domain graphic available

Description Kazal-type serine protease inhibitor domain-containing protein 1 precursor.
KAZD1_MOUSE
 
θ value θ > 10 (rank : 54) NC score 0.201202 (rank : 15)
Query Neighborhood Hits 29 Target Neighborhood Hits 281 Shared Neighborhood Hits 5
SwissProt Accessions Q8BJ66 Gene names Kazald1, Bono1, Igfbprp10
Domain
Architecture

No domain graphic available

Description Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).
LCE1A_HUMAN
 
θ value θ > 10 (rank : 55) NC score 0.142001 (rank : 20)
Query Neighborhood Hits 29 Target Neighborhood Hits 47 Shared Neighborhood Hits 2
SwissProt Accessions Q5T7P2 Gene names LCE1A, LEP1
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 1A (Late envelope protein 1).
LCE1B_HUMAN
 
θ value θ > 10 (rank : 56) NC score 0.221630 (rank : 13)
Query Neighborhood Hits 29 Target Neighborhood Hits 58 Shared Neighborhood Hits 5
SwissProt Accessions Q5T7P3 Gene names LCE1B, LEP2, SPRL2A
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).
LCE1C_HUMAN
 
θ value θ > 10 (rank : 57) NC score 0.253759 (rank : 11)
Query Neighborhood Hits 29 Target Neighborhood Hits 65 Shared Neighborhood Hits 5
SwissProt Accessions Q5T751 Gene names LCE1C, LEP3
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 1C (Late envelope protein 3).
LCE1D_HUMAN
 
θ value θ > 10 (rank : 58) NC score 0.223009 (rank : 12)
Query Neighborhood Hits 29 Target Neighborhood Hits 44 Shared Neighborhood Hits 5
SwissProt Accessions Q5T752 Gene names LCE1D, LEP4
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 1D (Late envelope protein 4).
LCE1E_HUMAN
 
θ value θ > 10 (rank : 59) NC score 0.274901 (rank : 8)
Query Neighborhood Hits 29 Target Neighborhood Hits 53 Shared Neighborhood Hits 5
SwissProt Accessions Q5T753 Gene names LCE1E, LEP5
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 1E (Late envelope protein 5).
LCE1F_HUMAN
 
θ value θ > 10 (rank : 60) NC score 0.128633 (rank : 21)
Query Neighborhood Hits 29 Target Neighborhood Hits 48 Shared Neighborhood Hits 3
SwissProt Accessions Q5T754 Gene names LCE1F, LEP6
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 1F (Late envelope protein 6).
LCE2A_HUMAN
 
θ value θ > 10 (rank : 61) NC score 0.065671 (rank : 50)
Query Neighborhood Hits 29 Target Neighborhood Hits 50 Shared Neighborhood Hits 2
SwissProt Accessions Q5TA79 Gene names LCE2A, LEP9
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 2A (Late envelope protein 9).
LCE2B_HUMAN
 
θ value θ > 10 (rank : 62) NC score 0.106293 (rank : 25)
Query Neighborhood Hits 29 Target Neighborhood Hits 50 Shared Neighborhood Hits 3
SwissProt Accessions O14633 Gene names LCE2B, LEP10, SPRL1B, XP5
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).
LCE2C_HUMAN
 
θ value θ > 10 (rank : 63) NC score 0.086699 (rank : 33)
Query Neighborhood Hits 29 Target Neighborhood Hits 53 Shared Neighborhood Hits 3
SwissProt Accessions Q5TA81 Gene names LCE2C, LEP11
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 2C (Late envelope protein 11).
LCE2D_HUMAN
 
θ value θ > 10 (rank : 64) NC score 0.107473 (rank : 24)
Query Neighborhood Hits 29 Target Neighborhood Hits 50 Shared Neighborhood Hits 3
SwissProt Accessions Q5TA82 Gene names LCE2D, LEP12, SPRL1A
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).
LCE4A_HUMAN
 
θ value θ > 10 (rank : 65) NC score 0.060173 (rank : 52)
Query Neighborhood Hits 29 Target Neighborhood Hits 26 Shared Neighborhood Hits 2
SwissProt Accessions Q5TA78 Gene names LCE4A, LEP8, SPRL4A
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).
LCE5A_HUMAN
 
θ value θ > 10 (rank : 66) NC score 0.122368 (rank : 22)
Query Neighborhood Hits 29 Target Neighborhood Hits 43 Shared Neighborhood Hits 3
SwissProt Accessions Q5TCM9 Gene names LCE5A, LEP18, SPRL5A
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).
NOV_HUMAN
 
θ value θ > 10 (rank : 67) NC score 0.083373 (rank : 35)
Query Neighborhood Hits 29 Target Neighborhood Hits 128 Shared Neighborhood Hits 5
SwissProt Accessions P48745, Q96BY5 Gene names NOV, CCN3, IGFBP9, NOVH
Domain
Architecture
Description Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).
NOV_MOUSE
 
θ value θ > 10 (rank : 68) NC score 0.075672 (rank : 42)
Query Neighborhood Hits 29 Target Neighborhood Hits 130 Shared Neighborhood Hits 5
SwissProt Accessions Q64299, Q8CA67 Gene names Nov, Ccn3
Domain
Architecture
Description Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).
PDZD3_HUMAN
 
θ value θ > 10 (rank : 69) NC score 0.075920 (rank : 41)
Query Neighborhood Hits 29 Target Neighborhood Hits 180 Shared Neighborhood Hits 24
SwissProt Accessions Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3 Gene names PDZD3, IKEPP, PDZK2
Domain
Architecture

No domain graphic available

Description PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).
PDZD3_MOUSE
 
θ value θ > 10 (rank : 70) NC score 0.075543 (rank : 43)
Query Neighborhood Hits 29 Target Neighborhood Hits 171 Shared Neighborhood Hits 23
SwissProt Accessions Q99MJ6, Q8BWE5 Gene names Pdzd3, Pdzk2
Domain
Architecture

No domain graphic available

Description PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).
RHPN1_HUMAN
 
θ value θ > 10 (rank : 71) NC score 0.054532 (rank : 57)
Query Neighborhood Hits 29 Target Neighborhood Hits 158 Shared Neighborhood Hits 23
SwissProt Accessions Q8TCX5, Q8TAV1 Gene names RHPN1
Domain
Architecture
Description Rhophilin-1 (GTP-Rho-binding protein 1).
RHPN1_MOUSE
 
θ value θ > 10 (rank : 72) NC score 0.051426 (rank : 60)
Query Neighborhood Hits 29 Target Neighborhood Hits 154 Shared Neighborhood Hits 22
SwissProt Accessions Q61085 Gene names Rhpn1, Grbp
Domain
Architecture
Description Rhophilin-1 (GTP-Rho-binding protein 1).
TX1B3_HUMAN
 
θ value θ > 10 (rank : 73) NC score 0.050975 (rank : 61)
Query Neighborhood Hits 29 Target Neighborhood Hits 161 Shared Neighborhood Hits 21
SwissProt Accessions O14907, Q7LCQ4 Gene names TAX1BP3, TIP1
Domain
Architecture

No domain graphic available

Description Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).
TX1B3_MOUSE
 
θ value θ > 10 (rank : 74) NC score 0.050370 (rank : 63)
Query Neighborhood Hits 29 Target Neighborhood Hits 158 Shared Neighborhood Hits 21
SwissProt Accessions Q9DBG9 Gene names Tax1bp3
Domain
Architecture

No domain graphic available

Description Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).
WHRN_MOUSE
 
θ value θ > 10 (rank : 75) NC score 0.050090 (rank : 64)
Query Neighborhood Hits 29 Target Neighborhood Hits 412 Shared Neighborhood Hits 23
SwissProt Accessions Q80VW5, Q80TC2, Q80VW4 Gene names Whrn, Kiaa1526
Domain
Architecture

No domain graphic available

Description Whirlin.
WISP2_HUMAN
 
θ value θ > 10 (rank : 76) NC score 0.088115 (rank : 32)
Query Neighborhood Hits 29 Target Neighborhood Hits 126 Shared Neighborhood Hits 5
SwissProt Accessions O76076 Gene names WISP2, CCN5, CT58, CTGFL
Domain
Architecture

No domain graphic available

Description WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).
WISP2_MOUSE
 
θ value θ > 10 (rank : 77) NC score 0.057522 (rank : 54)
Query Neighborhood Hits 29 Target Neighborhood Hits 129 Shared Neighborhood Hits 5
SwissProt Accessions Q9Z0G4, Q8CIC8 Gene names Wisp2, Ccn5, Ctgfl
Domain
Architecture
Description WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).
WISP3_HUMAN
 
θ value θ > 10 (rank : 78) NC score 0.068044 (rank : 49)
Query Neighborhood Hits 29 Target Neighborhood Hits 87 Shared Neighborhood Hits 5
SwissProt Accessions O95389, Q6UXH6 Gene names WISP3, CCN6
Domain
Architecture

No domain graphic available

Description WNT1-inducible signaling pathway protein 3 precursor (WISP-3).

Hits sorted by NC score


HTRA2_MOUSE
 
NC score 0.999962 (rank : 1) θ value 0 (rank : 1)
Query Neighborhood Hits 29 Target Neighborhood Hits 29 Shared Neighborhood Hits 29
SwissProt Accessions Q9JIY5, Q9R108 Gene names Htra2, Omi, Prss25
Domain
Architecture
Description Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).
HTRA2_HUMAN
 
NC score 0.997314 (rank : 2) θ value 7.71569e-185 (rank : 2)
Query Neighborhood Hits 29 Target Neighborhood Hits 30 Shared Neighborhood Hits 22
SwissProt Accessions O43464, Q9HBZ4, Q9P0Y3, Q9P0Y4 Gene names HTRA2, OMI, PRSS25
Domain
Architecture
Description Serine protease HTRA2, mitochondrial precursor (EC 3.4.21.-) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine proteinase OMI).
HTRA4_HUMAN
 
NC score 0.911642 (rank : 3) θ value 6.73165e-80 (rank : 7)
Query Neighborhood Hits 29 Target Neighborhood Hits 119 Shared Neighborhood Hits 12
SwissProt Accessions P83105, Q542Z4, Q6PF13 Gene names HTRA4
Domain
Architecture

No domain graphic available

Description Probable serine protease HTRA4 precursor (EC 3.4.21.-).
HTRA3_HUMAN
 
NC score 0.908186 (rank : 4) θ value 4.06505e-93 (rank : 3)
Query Neighborhood Hits 29 Target Neighborhood Hits 152 Shared Neighborhood Hits 19
SwissProt Accessions P83110, Q7Z7A2 Gene names HTRA3, PRSP
Domain
Architecture
Description Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease).
HTRA3_MOUSE
 
NC score 0.904267 (rank : 5) θ value 5.86991e-92 (rank : 4)
Query Neighborhood Hits 29 Target Neighborhood Hits 156 Shared Neighborhood Hits 20
SwissProt Accessions Q9D236, Q6WLC5, Q6YDR0 Gene names Htra3, Prsp, Tasp
Domain
Architecture
Description Probable serine protease HTRA3 precursor (EC 3.4.21.-) (High- temperature requirement factor A3) (Pregnancy-related serine protease) (Toll-associated serine protease).
HTRA1_MOUSE
 
NC score 0.873310 (rank : 6) θ value 1.03614e-88 (rank : 6)
Query Neighborhood Hits 29 Target Neighborhood Hits 140 Shared Neighborhood Hits 15
SwissProt Accessions Q9R118 Gene names Htra1, Htra, Prss11
Domain
Architecture
Description Serine protease HTRA1 precursor (EC 3.4.21.-).
HTRA1_HUMAN
 
NC score 0.869951 (rank : 7) θ value 8.47616e-91 (rank : 5)
Query Neighborhood Hits 29 Target Neighborhood Hits 155 Shared Neighborhood Hits 16
SwissProt Accessions Q92743, Q9UNS5 Gene names HTRA1, HTRA, PRSS11
Domain
Architecture
Description Serine protease HTRA1 precursor (EC 3.4.21.-) (L56).
LCE1E_HUMAN
 
NC score 0.274901 (rank : 8) θ value θ > 10 (rank : 59)
Query Neighborhood Hits 29 Target Neighborhood Hits 53 Shared Neighborhood Hits 5
SwissProt Accessions Q5T753 Gene names LCE1E, LEP5
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 1E (Late envelope protein 5).
IBP7_HUMAN
 
NC score 0.267673 (rank : 9) θ value θ > 10 (rank : 49)
Query Neighborhood Hits 29 Target Neighborhood Hits 220 Shared Neighborhood Hits 5
SwissProt Accessions Q16270, Q07822 Gene names IGFBP7, MAC25, PSF
Domain
Architecture
Description Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).
IBP7_MOUSE
 
NC score 0.261008 (rank : 10) θ value θ > 10 (rank : 50)
Query Neighborhood Hits 29 Target Neighborhood Hits 230 Shared Neighborhood Hits 5
SwissProt Accessions Q61581, O88812, Q9EQW0 Gene names Igfbp7, Mac25
Domain
Architecture
Description Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).
LCE1C_HUMAN
 
NC score 0.253759 (rank : 11) θ value θ > 10 (rank : 57)
Query Neighborhood Hits 29 Target Neighborhood Hits 65 Shared Neighborhood Hits 5
SwissProt Accessions Q5T751 Gene names LCE1C, LEP3
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 1C (Late envelope protein 3).
LCE1D_HUMAN
 
NC score 0.223009 (rank : 12) θ value θ > 10 (rank : 58)
Query Neighborhood Hits 29 Target Neighborhood Hits 44 Shared Neighborhood Hits 5
SwissProt Accessions Q5T752 Gene names LCE1D, LEP4
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 1D (Late envelope protein 4).
LCE1B_HUMAN
 
NC score 0.221630 (rank : 13) θ value θ > 10 (rank : 56)
Query Neighborhood Hits 29 Target Neighborhood Hits 58 Shared Neighborhood Hits 5
SwissProt Accessions Q5T7P3 Gene names LCE1B, LEP2, SPRL2A
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).
KAZD1_HUMAN
 
NC score 0.211756 (rank : 14) θ value θ > 10 (rank : 53)
Query Neighborhood Hits 29 Target Neighborhood Hits 248 Shared Neighborhood Hits 5
SwissProt Accessions Q96I82, Q6ZMB1, Q9BQ73 Gene names KAZALD1
Domain
Architecture

No domain graphic available

Description Kazal-type serine protease inhibitor domain-containing protein 1 precursor.
KAZD1_MOUSE
 
NC score 0.201202 (rank : 15) θ value θ > 10 (rank : 54)
Query Neighborhood Hits 29 Target Neighborhood Hits 281 Shared Neighborhood Hits 5
SwissProt Accessions Q8BJ66 Gene names Kazald1, Bono1, Igfbprp10
Domain
Architecture

No domain graphic available

Description Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).
ESM1_MOUSE
 
NC score 0.200624 (rank : 16) θ value θ > 10 (rank : 36)
Query Neighborhood Hits 29 Target Neighborhood Hits 107 Shared Neighborhood Hits 5
SwissProt Accessions Q9QYY7 Gene names Esm1
Domain
Architecture
Description Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).
ESM1_HUMAN
 
NC score 0.195688 (rank : 17) θ value θ > 10 (rank : 35)
Query Neighborhood Hits 29 Target Neighborhood Hits 110 Shared Neighborhood Hits 5
SwissProt Accessions Q9NQ30, Q15330, Q96ES3 Gene names ESM1
Domain
Architecture

No domain graphic available

Description Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).
PDZ11_HUMAN
 
NC score 0.149503 (rank : 18) θ value 0.00102713 (rank : 8)
Query Neighborhood Hits 29 Target Neighborhood Hits 160 Shared Neighborhood Hits 24
SwissProt Accessions Q5EBL8, Q6UWE1, Q9P0Q1 Gene names PDZD11, PDZK11
Domain
Architecture

No domain graphic available

Description PDZ domain-containing protein 11.
PDZ11_MOUSE
 
NC score 0.147660 (rank : 19) θ value 0.00102713 (rank : 9)
Query Neighborhood Hits 29 Target Neighborhood Hits 154 Shared Neighborhood Hits 23
SwissProt Accessions Q9CZG9 Gene names Pdzd11, Pdzk11
Domain
Architecture

No domain graphic available

Description PDZ domain-containing protein 11.
LCE1A_HUMAN
 
NC score 0.142001 (rank : 20) θ value θ > 10 (rank : 55)
Query Neighborhood Hits 29 Target Neighborhood Hits 47 Shared Neighborhood Hits 2
SwissProt Accessions Q5T7P2 Gene names LCE1A, LEP1
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 1A (Late envelope protein 1).
LCE1F_HUMAN
 
NC score 0.128633 (rank : 21) θ value θ > 10 (rank : 60)
Query Neighborhood Hits 29 Target Neighborhood Hits 48 Shared Neighborhood Hits 3
SwissProt Accessions Q5T754 Gene names LCE1F, LEP6
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 1F (Late envelope protein 6).
LCE5A_HUMAN
 
NC score 0.122368 (rank : 22) θ value θ > 10 (rank : 66)
Query Neighborhood Hits 29 Target Neighborhood Hits 43 Shared Neighborhood Hits 3
SwissProt Accessions Q5TCM9 Gene names LCE5A, LEP18, SPRL5A
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).
IBP3_HUMAN
 
NC score 0.109939 (rank : 23) θ value θ > 10 (rank : 43)
Query Neighborhood Hits 29 Target Neighborhood Hits 67 Shared Neighborhood Hits 5
SwissProt Accessions P17936, Q2V509, Q6P1M6 Gene names IGFBP3, IBP3
Domain
Architecture
Description Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).
LCE2D_HUMAN
 
NC score 0.107473 (rank : 24) θ value θ > 10 (rank : 64)
Query Neighborhood Hits 29 Target Neighborhood Hits 50 Shared Neighborhood Hits 3
SwissProt Accessions Q5TA82 Gene names LCE2D, LEP12, SPRL1A
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A).
LCE2B_HUMAN
 
NC score 0.106293 (rank : 25) θ value θ > 10 (rank : 62)
Query Neighborhood Hits 29 Target Neighborhood Hits 50 Shared Neighborhood Hits 3
SwissProt Accessions O14633 Gene names LCE2B, LEP10, SPRL1B, XP5
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 2B (Late envelope protein 10) (Small proline-rich-like epidermal differentiation complex protein 1B) (Skin- specific protein Xp5).
ISK3_MOUSE
 
NC score 0.100547 (rank : 26) θ value θ > 10 (rank : 52)
Query Neighborhood Hits 29 Target Neighborhood Hits 36 Shared Neighborhood Hits 5
SwissProt Accessions P09036, Q5M9M3 Gene names Spink3
Domain
Architecture
Description Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).
PDZD1_HUMAN
 
NC score 0.097524 (rank : 27) θ value 1.38821 (rank : 11)
Query Neighborhood Hits 29 Target Neighborhood Hits 190 Shared Neighborhood Hits 23
SwissProt Accessions Q5T2W1, O60450, Q5T5P6, Q9BQ41 Gene names PDZK1, CAP70, NHERF3, PDZD1
Domain
Architecture

No domain graphic available

Description PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).
PDZD1_MOUSE
 
NC score 0.096464 (rank : 28) θ value 1.81305 (rank : 16)
Query Neighborhood Hits 29 Target Neighborhood Hits 191 Shared Neighborhood Hits 24
SwissProt Accessions Q9JIL4, Q8CDP5, Q8R4G2, Q9CQ72 Gene names Pdzk1, Cap70, Nherf3
Domain
Architecture

No domain graphic available

Description PDZ domain-containing protein 1 (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory factor 3) (Sodium-hydrogen exchanger regulatory factor 3).
IBP1_MOUSE
 
NC score 0.094675 (rank : 29) θ value θ > 10 (rank : 40)
Query Neighborhood Hits 29 Target Neighborhood Hits 97 Shared Neighborhood Hits 5
SwissProt Accessions P47876, Q61732 Gene names Igfbp1, Igfbp-1
Domain
Architecture
Description Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1).
CYR61_MOUSE
 
NC score 0.090206 (rank : 30) θ value θ > 10 (rank : 34)
Query Neighborhood Hits 29 Target Neighborhood Hits 156 Shared Neighborhood Hits 5
SwissProt Accessions P18406 Gene names Cyr61, Ccn1, Igfbp10
Domain
Architecture
Description Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (3CH61).
CYR61_HUMAN
 
NC score 0.090041 (rank : 31) θ value θ > 10 (rank : 33)
Query Neighborhood Hits 29 Target Neighborhood Hits 159 Shared Neighborhood Hits 5
SwissProt Accessions O00622, O14934, O43775, Q9BZL7 Gene names CYR61, CCN1, GIG1, IGFBP10
Domain
Architecture
Description Protein CYR61 precursor (Cysteine-rich, angiogenic inducer, 61) (Insulin-like growth factor-binding protein 10) (Protein GIG1).
WISP2_HUMAN
 
NC score 0.088115 (rank : 32) θ value θ > 10 (rank : 76)
Query Neighborhood Hits 29 Target Neighborhood Hits 126 Shared Neighborhood Hits 5
SwissProt Accessions O76076 Gene names WISP2, CCN5, CT58, CTGFL
Domain
Architecture

No domain graphic available

Description WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L) (Connective tissue growth factor-related protein 58).
LCE2C_HUMAN
 
NC score 0.086699 (rank : 33) θ value θ > 10 (rank : 63)
Query Neighborhood Hits 29 Target Neighborhood Hits 53 Shared Neighborhood Hits 3
SwissProt Accessions Q5TA81 Gene names LCE2C, LEP11
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 2C (Late envelope protein 11).
IBP2_HUMAN
 
NC score 0.085589 (rank : 34) θ value θ > 10 (rank : 41)
Query Neighborhood Hits 29 Target Neighborhood Hits 61 Shared Neighborhood Hits 5
SwissProt Accessions P18065, Q14619, Q9UCL3 Gene names IGFBP2, BP2
Domain
Architecture
Description Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).
NOV_HUMAN
 
NC score 0.083373 (rank : 35) θ value θ > 10 (rank : 67)
Query Neighborhood Hits 29 Target Neighborhood Hits 128 Shared Neighborhood Hits 5
SwissProt Accessions P48745, Q96BY5 Gene names NOV, CCN3, IGFBP9, NOVH
Domain
Architecture
Description Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).
IBP5_MOUSE
 
NC score 0.082069 (rank : 36) θ value θ > 10 (rank : 48)
Query Neighborhood Hits 29 Target Neighborhood Hits 68 Shared Neighborhood Hits 5
SwissProt Accessions Q07079 Gene names Igfbp5, Igfbp-5
Domain
Architecture
Description Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).
IBP5_HUMAN
 
NC score 0.081927 (rank : 37) θ value θ > 10 (rank : 47)
Query Neighborhood Hits 29 Target Neighborhood Hits 68 Shared Neighborhood Hits 5
SwissProt Accessions P24593 Gene names IGFBP5, IBP5
Domain
Architecture
Description Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).
CRIM1_HUMAN
 
NC score 0.079366 (rank : 38) θ value θ > 10 (rank : 30)
Query Neighborhood Hits 29 Target Neighborhood Hits 362 Shared Neighborhood Hits 5
SwissProt Accessions Q9NZV1, Q59GH0, Q7LCQ5, Q9H318 Gene names CRIM1
Domain
Architecture

No domain graphic available

Description Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).
IBP3_MOUSE
 
NC score 0.078777 (rank : 39) θ value θ > 10 (rank : 44)
Query Neighborhood Hits 29 Target Neighborhood Hits 60 Shared Neighborhood Hits 5
SwissProt Accessions P47878 Gene names Igfbp3, Igfbp-3
Domain
Architecture
Description Insulin-like growth factor-binding protein 3 precursor (IGFBP-3) (IBP- 3) (IGF-binding protein 3).
CTGF_HUMAN
 
NC score 0.076413 (rank : 40) θ value θ > 10 (rank : 31)
Query Neighborhood Hits 29 Target Neighborhood Hits 128 Shared Neighborhood Hits 5
SwissProt Accessions P29279, Q96QX2 Gene names CTGF, CCN2, HCS24
Domain
Architecture
Description Connective tissue growth factor precursor (Hypertrophic chondrocyte- specific protein 24).
PDZD3_HUMAN
 
NC score 0.075920 (rank : 41) θ value θ > 10 (rank : 69)
Query Neighborhood Hits 29 Target Neighborhood Hits 180 Shared Neighborhood Hits 24
SwissProt Accessions Q86UT5, Q8N6R4, Q8NAW7, Q8NEX7, Q9H5Z3 Gene names PDZD3, IKEPP, PDZK2
Domain
Architecture

No domain graphic available

Description PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Intestinal and kidney-enriched PDZ protein) (Protein DLNB27).
NOV_MOUSE
 
NC score 0.075672 (rank : 42) θ value θ > 10 (rank : 68)
Query Neighborhood Hits 29 Target Neighborhood Hits 130 Shared Neighborhood Hits 5
SwissProt Accessions Q64299, Q8CA67 Gene names Nov, Ccn3
Domain
Architecture
Description Protein NOV homolog precursor (NovH) (Nephroblastoma overexpressed gene protein homolog).
PDZD3_MOUSE
 
NC score 0.075543 (rank : 43) θ value θ > 10 (rank : 70)
Query Neighborhood Hits 29 Target Neighborhood Hits 171 Shared Neighborhood Hits 23
SwissProt Accessions Q99MJ6, Q8BWE5 Gene names Pdzd3, Pdzk2
Domain
Architecture

No domain graphic available

Description PDZ domain-containing protein 3 (PDZ domain-containing protein 2) (Natrium-phosphate cotransporter IIa C-terminal-associated protein 2) (NaPi-Cap2).
IBP2_MOUSE
 
NC score 0.073374 (rank : 44) θ value θ > 10 (rank : 42)
Query Neighborhood Hits 29 Target Neighborhood Hits 65 Shared Neighborhood Hits 5
SwissProt Accessions P47877, Q61722 Gene names Igfbp2, Igfbp-2
Domain
Architecture
Description Insulin-like growth factor-binding protein 2 precursor (IGFBP-2) (IBP- 2) (IGF-binding protein 2).
NHERF_HUMAN
 
NC score 0.073313 (rank : 45) θ value 5.27518 (rank : 23)
Query Neighborhood Hits 29 Target Neighborhood Hits 190 Shared Neighborhood Hits 23
SwissProt Accessions O14745, O43552, Q86WQ5 Gene names SLC9A3R1, NHERF
Domain
Architecture
Description Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).
NHERF_MOUSE
 
NC score 0.070215 (rank : 46) θ value 8.99809 (rank : 28)
Query Neighborhood Hits 29 Target Neighborhood Hits 195 Shared Neighborhood Hits 23
SwissProt Accessions P70441 Gene names Slc9a3r1, Nherf
Domain
Architecture
Description Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) (Na(+)/H(+) exchange regulatory cofactor NHE-RF) (NHERF-1) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform 3 regulatory factor 1).
IPK1_HUMAN
 
NC score 0.070042 (rank : 47) θ value θ > 10 (rank : 51)
Query Neighborhood Hits 29 Target Neighborhood Hits 38 Shared Neighborhood Hits 4
SwissProt Accessions P00995 Gene names SPINK1, PSTI
Domain
Architecture
Description Pancreatic secretory trypsin inhibitor precursor (Tumor-associated trypsin inhibitor) (TATI) (Serine protease inhibitor Kazal-type 1).
IBP4_HUMAN
 
NC score 0.068540 (rank : 48) θ value θ > 10 (rank : 45)
Query Neighborhood Hits 29 Target Neighborhood Hits 52 Shared Neighborhood Hits 4
SwissProt Accessions P22692 Gene names IGFBP4, IBP4
Domain
Architecture
Description Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).
WISP3_HUMAN
 
NC score 0.068044 (rank : 49) θ value θ > 10 (rank : 78)
Query Neighborhood Hits 29 Target Neighborhood Hits 87 Shared Neighborhood Hits 5
SwissProt Accessions O95389, Q6UXH6 Gene names WISP3, CCN6
Domain
Architecture

No domain graphic available

Description WNT1-inducible signaling pathway protein 3 precursor (WISP-3).
LCE2A_HUMAN
 
NC score 0.065671 (rank : 50) θ value θ > 10 (rank : 61)
Query Neighborhood Hits 29 Target Neighborhood Hits 50 Shared Neighborhood Hits 2
SwissProt Accessions Q5TA79 Gene names LCE2A, LEP9
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 2A (Late envelope protein 9).
IBP4_MOUSE
 
NC score 0.064559 (rank : 51) θ value θ > 10 (rank : 46)
Query Neighborhood Hits 29 Target Neighborhood Hits 55 Shared Neighborhood Hits 4
SwissProt Accessions P47879, O35666 Gene names Igfbp4, Igfbp-4
Domain
Architecture
Description Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP- 4) (IGF-binding protein 4).
LCE4A_HUMAN
 
NC score 0.060173 (rank : 52) θ value θ > 10 (rank : 65)
Query Neighborhood Hits 29 Target Neighborhood Hits 26 Shared Neighborhood Hits 2
SwissProt Accessions Q5TA78 Gene names LCE4A, LEP8, SPRL4A
Domain
Architecture

No domain graphic available

Description Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).
IBP1_HUMAN
 
NC score 0.058195 (rank : 53) θ value θ > 10 (rank : 39)
Query Neighborhood Hits 29 Target Neighborhood Hits 67 Shared Neighborhood Hits 2
SwissProt Accessions P08833, Q8IYP5 Gene names IGFBP1, IBP1
Domain
Architecture
Description Insulin-like growth factor-binding protein 1 precursor (IGFBP-1) (IBP- 1) (IGF-binding protein 1) (Placental protein 12) (PP12).
WISP2_MOUSE
 
NC score 0.057522 (rank : 54) θ value θ > 10 (rank : 77)
Query Neighborhood Hits 29 Target Neighborhood Hits 129 Shared Neighborhood Hits 5
SwissProt Accessions Q9Z0G4, Q8CIC8 Gene names Wisp2, Ccn5, Ctgfl
Domain
Architecture
Description WNT1-inducible signaling pathway protein 2 precursor (WISP-2) (Connective tissue growth factor-like protein) (CTGF-L).
SDCB1_HUMAN
 
NC score 0.057227 (rank : 55) θ value 4.03905 (rank : 21)
Query Neighborhood Hits 29 Target Neighborhood Hits 150 Shared Neighborhood Hits 17
SwissProt Accessions O00560, O00173, O43391 Gene names SDCBP, MDA9, SYCL
Domain
Architecture
Description Syntenin-1 (Syndecan-binding protein 1) (Melanoma differentiation- associated protein 9) (MDA-9) (Scaffold protein Pbp1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18).
CTGF_MOUSE
 
NC score 0.054970 (rank : 56) θ value θ > 10 (rank : 32)
Query Neighborhood Hits 29 Target Neighborhood Hits 124 Shared Neighborhood Hits 5
SwissProt Accessions P29268, Q922U0 Gene names Ctgf, Ccn2, Fisp-12, Fisp12, Hcs24
Domain
Architecture
Description Connective tissue growth factor precursor (Protein FISP-12) (Hypertrophic chondrocyte-specific protein 24).
RHPN1_HUMAN
 
NC score 0.054532 (rank : 57) θ value θ > 10 (rank : 71)
Query Neighborhood Hits 29 Target Neighborhood Hits 158 Shared Neighborhood Hits 23
SwissProt Accessions Q8TCX5, Q8TAV1 Gene names RHPN1
Domain
Architecture
Description Rhophilin-1 (GTP-Rho-binding protein 1).
SDCB1_MOUSE
 
NC score 0.053744 (rank : 58) θ value 5.27518 (rank : 25)
Query Neighborhood Hits 29 Target Neighborhood Hits 144 Shared Neighborhood Hits 17
SwissProt Accessions O08992, Q544P5 Gene names Sdcbp
Domain
Architecture
Description Syntenin-1 (Syndecan-binding protein 1) (Scaffold protein Pbp1).
FSTL3_HUMAN
 
NC score 0.051772 (rank : 59) θ value θ > 10 (rank : 37)
Query Neighborhood Hits 29 Target Neighborhood Hits 162 Shared Neighborhood Hits 5
SwissProt Accessions O95633 Gene names FSTL3, FLRG
Domain
Architecture
Description Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).
RHPN1_MOUSE
 
NC score 0.051426 (rank : 60) θ value θ > 10 (rank : 72)
Query Neighborhood Hits 29 Target Neighborhood Hits 154 Shared Neighborhood Hits 22
SwissProt Accessions Q61085 Gene names Rhpn1, Grbp
Domain
Architecture
Description Rhophilin-1 (GTP-Rho-binding protein 1).
TX1B3_HUMAN
 
NC score 0.050975 (rank : 61) θ value θ > 10 (rank : 73)
Query Neighborhood Hits 29 Target Neighborhood Hits 161 Shared Neighborhood Hits 21
SwissProt Accessions O14907, Q7LCQ4 Gene names TAX1BP3, TIP1
Domain
Architecture

No domain graphic available

Description Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1) (Glutaminase-interacting protein 3).
FSTL3_MOUSE
 
NC score 0.050395 (rank : 62) θ value θ > 10 (rank : 38)
Query Neighborhood Hits 29 Target Neighborhood Hits 152 Shared Neighborhood Hits 5
SwissProt Accessions Q9EQC7 Gene names Fstl3, Flrg
Domain
Architecture
Description Follistatin-related protein 3 precursor (Follistatin-like 3) (Follistatin-related gene protein).
TX1B3_MOUSE
 
NC score 0.050370 (rank : 63) θ value θ > 10 (rank : 74)
Query Neighborhood Hits 29 Target Neighborhood Hits 158 Shared Neighborhood Hits 21
SwissProt Accessions Q9DBG9 Gene names Tax1bp3
Domain
Architecture

No domain graphic available

Description Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1).
WHRN_MOUSE
 
NC score 0.050090 (rank : 64) θ value θ > 10 (rank : 75)
Query Neighborhood Hits 29 Target Neighborhood Hits 412 Shared Neighborhood Hits 23
SwissProt Accessions Q80VW5, Q80TC2, Q80VW4 Gene names Whrn, Kiaa1526
Domain
Architecture

No domain graphic available

Description Whirlin.
PDLI3_HUMAN
 
NC score 0.044068 (rank : 65) θ value 0.813845 (rank : 10)
Query Neighborhood Hits 29 Target Neighborhood Hits 199 Shared Neighborhood Hits 15
SwissProt Accessions Q53GG5, O43590, O60439, O60440, Q8N6Y6, Q9BVP4 Gene names PDLIM3, ALP
Domain
Architecture

No domain graphic available

Description PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).
GRIP2_HUMAN
 
NC score 0.044051 (rank : 66) θ value 3.0926 (rank : 19)
Query Neighborhood Hits 29 Target Neighborhood Hits 256 Shared Neighborhood Hits 22
SwissProt Accessions Q9C0E4, Q8TEH9, Q9H7H3 Gene names GRIP2, KIAA1719
Domain
Architecture
Description Glutamate receptor-interacting protein 2 (GRIP2 protein).
LAP4_HUMAN
 
NC score 0.041356 (rank : 67) θ value 2.36792 (rank : 17)
Query Neighborhood Hits 29 Target Neighborhood Hits 608 Shared Neighborhood Hits 25
SwissProt Accessions Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1 Gene names SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain
Architecture

No domain graphic available

Description Protein LAP4 (Protein scribble homolog) (hScrib).
PDLI2_MOUSE
 
NC score 0.041172 (rank : 68) θ value 4.03905 (rank : 20)
Query Neighborhood Hits 29 Target Neighborhood Hits 220 Shared Neighborhood Hits 17
SwissProt Accessions Q8R1G6 Gene names Pdlim2
Domain
Architecture

No domain graphic available

Description PDZ and LIM domain protein 2 (PDZ-LIM protein mystique).
PDLI3_MOUSE
 
NC score 0.038024 (rank : 69) θ value 2.36792 (rank : 18)
Query Neighborhood Hits 29 Target Neighborhood Hits 197 Shared Neighborhood Hits 15
SwissProt Accessions O70209 Gene names Pdlim3
Domain
Architecture

No domain graphic available

Description PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha- actinin-2-associated LIM protein).
LAP4_MOUSE
 
NC score 0.036730 (rank : 70) θ value 1.81305 (rank : 13)
Query Neighborhood Hits 29 Target Neighborhood Hits 590 Shared Neighborhood Hits 25
SwissProt Accessions Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3 Gene names Scrib, Kiaa0147, Lap4, Scrib1
Domain
Architecture

No domain graphic available

Description Protein LAP4 (Protein scribble homolog).
PDLI2_HUMAN
 
NC score 0.031905 (rank : 71) θ value 8.99809 (rank : 29)
Query Neighborhood Hits 29 Target Neighborhood Hits 245 Shared Neighborhood Hits 16
SwissProt Accessions Q96JY6, Q7Z584, Q86WM8, Q8WZ29, Q9H4L9, Q9H7I2 Gene names PDLIM2
Domain
Architecture

No domain graphic available

Description PDZ and LIM domain protein 2 (PDZ-LIM protein mystique) (PDZ-LIM protein).
PARP6_HUMAN
 
NC score 0.028501 (rank : 72) θ value 1.81305 (rank : 14)
Query Neighborhood Hits 29 Target Neighborhood Hits 16 Shared Neighborhood Hits 3
SwissProt Accessions Q2NL67, Q9H7C5, Q9H9X6, Q9HAF3, Q9NPS6, Q9UFG4 Gene names PARP6
Domain
Architecture

No domain graphic available

Description Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).
PARP6_MOUSE
 
NC score 0.028496 (rank : 73) θ value 1.81305 (rank : 15)
Query Neighborhood Hits 29 Target Neighborhood Hits 17 Shared Neighborhood Hits 3
SwissProt Accessions Q6P6P7, Q8BVW1 Gene names Parp6
Domain
Architecture

No domain graphic available

Description Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).
DLG5_HUMAN
 
NC score 0.028408 (rank : 74) θ value 1.81305 (rank : 12)
Query Neighborhood Hits 29 Target Neighborhood Hits 1088 Shared Neighborhood Hits 19
SwissProt Accessions Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3 Gene names DLG5, KIAA0583, PDLG
Domain
Architecture
Description Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).
RGS12_HUMAN
 
NC score 0.024669 (rank : 75) θ value 5.27518 (rank : 24)
Query Neighborhood Hits 29 Target Neighborhood Hits 333 Shared Neighborhood Hits 19
SwissProt Accessions O14924, O14922, O14923, O43510, O75338 Gene names RGS12
Domain
Architecture
Description Regulator of G-protein signaling 12 (RGS12).
CREG2_HUMAN
 
NC score 0.015628 (rank : 76) θ value 8.99809 (rank : 27)
Query Neighborhood Hits 29 Target Neighborhood Hits 11 Shared Neighborhood Hits 3
SwissProt Accessions Q8IUH2, Q86X03, Q8N540, Q8N9E3 Gene names CREG2
Domain
Architecture

No domain graphic available

Description Protein CREG2 precursor.
SHAN1_HUMAN
 
NC score 0.014919 (rank : 77) θ value 5.27518 (rank : 26)
Query Neighborhood Hits 29 Target Neighborhood Hits 1041 Shared Neighborhood Hits 19
SwissProt Accessions Q9Y566, Q9NYW9 Gene names SHANK1
Domain
Architecture
Description SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).
ZN133_HUMAN
 
NC score -0.001030 (rank : 78) θ value 4.03905 (rank : 22)
Query Neighborhood Hits 29 Target Neighborhood Hits 784 Shared Neighborhood Hits 3
SwissProt Accessions P52736, Q9BUV2, Q9H443 Gene names ZNF133
Domain
Architecture
Description Zinc finger protein 133.