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Network neighborhood for query Sequence : SO2B1_MOUSE

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SO2B1_MOUSE
SwissProt Accessions	Q8BXB6, Q8BLV8	Gene names	Slco2b1, Slc21a9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SO2B1_HUMAN
θ value	0 (rank : 1)	NC score	0.998033 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	O94956, Q9H2Z0, Q9UFU1	Gene names	SLCO2B1, KIAA0880, OATPB, SLC21A9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9) (Organic anion transporter B) (OATP-B) (Organic anion transporter polypeptide-related protein 2) (OATP-RP2) (OATPRP2).

SO2B1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BXB6, Q8BLV8	Gene names	Slco2b1, Slc21a9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9).

SO2A1_MOUSE
θ value	8.33966e-147 (rank : 3)	NC score	0.988053 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	51	Shared Neighborhood Hits	21
SwissProt Accessions	Q9EPT5	Gene names	Slco2a1, Slc21a2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO2A1_HUMAN
θ value	1.33145e-144 (rank : 4)	NC score	0.988555 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	40	Shared Neighborhood Hits	22
SwissProt Accessions	Q92959	Gene names	SLCO2A1, SLC21A2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO3A1_HUMAN
θ value	2.01279e-100 (rank : 5)	NC score	0.974535 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UIG8, Q9BW73, Q9GZV2	Gene names	SLCO3A1, OATPD, SLC21A11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (Organic anion transporter polypeptide-related protein 3) (OATP-RP3) (OATPRP3) (PGE1 transporter).

SO3A1_MOUSE
θ value	5.48135e-98 (rank : 6)	NC score	0.973794 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	59	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R3L5, Q9CTV3, Q9JKV0	Gene names	Slco3a1, Oatpd, Slc21a11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (MJAM).

SO1C1_HUMAN
θ value	8.75112e-96 (rank : 7)	NC score	0.970208 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NYB5	Gene names	SLCO1C1, OATPF, SLC21A14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter polypeptide-related protein 5) (OAT-RP-5) (OATPRP5).

SO1A5_MOUSE
θ value	1.26366e-94 (rank : 8)	NC score	0.964006 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	31	Shared Neighborhood Hits	19
SwissProt Accessions	Q91YY5, Q91XS2	Gene names	Slco1a5, Oatp3, Slc21a7
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A5 (Solute carrier family 21 member 7) (Sodium-independent organic anion transporter 3) (Organic anion-transporting polypeptide 3).

SO1A1_MOUSE
θ value	9.37149e-90 (rank : 9)	NC score	0.962494 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXZ6	Gene names	Slco1a1, Slc21a1
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A1 (Solute carrier family 21 member 1) (Sodium-independent organic anion- transporting polypeptide 1) (OATP1).

SO1C1_MOUSE
θ value	2.72669e-89 (rank : 10)	NC score	0.968117 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ERB5, Q8BX54	Gene names	Slco1c1, Oatpf, Slc21a14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter 2) (OATP2).

SO1B2_MOUSE
θ value	3.56116e-89 (rank : 11)	NC score	0.968192 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	39	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JJL3, Q9JI79, Q9JJJ1	Gene names	Slco1b2, Slc21a10
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B2 (Solute carrier family 21 member 10) (Liver-specific organic anion transporter 1) (LST-1) (SLC21A6).

SO1A6_MOUSE
θ value	1.03614e-88 (rank : 12)	NC score	0.964860 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	Q99J94, Q3UQC6, Q9CUP7	Gene names	Slco1a6, Oatp5, Slc21a13
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A6 (Solute carrier family 21 member 13) (Kidney-specific organic anion- transporting polypeptide 5) (OATP-5).

SO1B3_HUMAN
θ value	7.42547e-87 (rank : 13)	NC score	0.966281 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NPD5	Gene names	SLCO1B3, LST2, SLC21A8
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B3 (Solute carrier family 21 member 8) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP8) (Liver-specific organic anion transporter 2) (LST-2).

SO1A2_HUMAN
θ value	2.16048e-86 (rank : 14)	NC score	0.962669 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	40	Shared Neighborhood Hits	19
SwissProt Accessions	P46721, Q9UGP7, Q9UL38	Gene names	SLCO1A2, OATP, SLC21A3
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A2 (Solute carrier family 21 member 3) (Sodium-independent organic anion transporter) (Organic anion-transporting polypeptide 1) (OATP1) (OATP- A).

SO1A4_MOUSE
θ value	1.82896e-85 (rank : 15)	NC score	0.961829 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	28	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EP96	Gene names	Slco1a4, Oatp2, Slc21a5
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A4 (Solute carrier family 21 member 5) (Sodium-independent organic anion- transporting polypeptide 2).

SO5A1_HUMAN
θ value	1.54831e-84 (rank : 16)	NC score	0.969993 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	57	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H2Y9	Gene names	SLCO5A1, SLC21A15
Domain Architecture
Description	Solute carrier organic anion transporter family member 5A1 (Solute carrier family 21 member 15) (Organic anion transporter polypeptide- related protein 4) (OATP-RP4) (OATPRP4).

SO1B1_HUMAN
θ value	1.00358e-83 (rank : 17)	NC score	0.964006 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6L6, Q9NQ37, Q9UBF3, Q9UH89	Gene names	SLCO1B1, LST1, OATP2, OATPC, SLC21A6
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B1 (Solute carrier family 21 member 6) (Sodium-independent organic anion- transporting polypeptide 2) (OATP 2) (Liver-specific organic anion transporter 1) (LST-1) (OATP-C).

SO4A1_HUMAN
θ value	4.22625e-74 (rank : 18)	NC score	0.960646 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	54	Shared Neighborhood Hits	19
SwissProt Accessions	Q96BD0, Q9H4T7, Q9H4T8, Q9H8P2, Q9NWX8, Q9UI35, Q9UIG7	Gene names	SLCO4A1, OATP1, OATPE, SLC21A12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT).

SO4A1_MOUSE
θ value	5.53243e-66 (rank : 19)	NC score	0.959256 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K078, Q8BZT4	Gene names	Slco4a1, Oatpe, Slc21a12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E).

ARI5B_HUMAN
θ value	0.47712 (rank : 20)	NC score	0.027645 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	328	Shared Neighborhood Hits	4
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

ARI5B_MOUSE
θ value	0.47712 (rank : 21)	NC score	0.030147 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	158	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

IL21R_MOUSE
θ value	1.38821 (rank : 22)	NC score	0.015339 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHX3, Q9ESM1	Gene names	Il21r, Nilr
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor) (Lymphocyte receptor beta) (LR-beta) (Novel cytokine receptor NR8).

KR10B_HUMAN
θ value	1.81305 (rank : 23)	NC score	0.025860 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	269	Shared Neighborhood Hits	13
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

S6A11_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.005647 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	P48066	Gene names	SLC6A11, GABT3, GAT3
Domain Architecture
Description	Sodium- and chloride-dependent GABA transporter 3.

KR108_HUMAN
θ value	2.36792 (rank : 25)	NC score	0.028119 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	226	Shared Neighborhood Hits	10
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

LRP1_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.002523 (rank : 38)
Query Neighborhood Hits	37	Target Neighborhood Hits	617	Shared Neighborhood Hits	9
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

KR10A_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.019275 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	232	Shared Neighborhood Hits	11
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

S6A11_MOUSE
θ value	4.03905 (rank : 28)	NC score	0.004953 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	P31650	Gene names	Slc6a11, Gabt4, Gat-4, Gat4
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent GABA transporter 4 (GAT4).

ANR50_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.000365 (rank : 40)
Query Neighborhood Hits	37	Target Neighborhood Hits	361	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

FA7_MOUSE
θ value	5.27518 (rank : 30)	NC score	0.000198 (rank : 41)
Query Neighborhood Hits	37	Target Neighborhood Hits	374	Shared Neighborhood Hits	4
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

MEGF6_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.004398 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	671	Shared Neighborhood Hits	12
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

KR10C_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.016658 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	219	Shared Neighborhood Hits	10
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

PHC3_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.007177 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	194	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

JAD1A_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.003416 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	328	Shared Neighborhood Hits	4
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

LAMA1_MOUSE
θ value	8.99809 (rank : 35)	NC score	0.001941 (rank : 39)
Query Neighborhood Hits	37	Target Neighborhood Hits	838	Shared Neighborhood Hits	9
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

NEB1_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.000109 (rank : 42)
Query Neighborhood Hits	37	Target Neighborhood Hits	829	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

PHC3_HUMAN
θ value	8.99809 (rank : 37)	NC score	0.006512 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	218	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

ISK3_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.050853 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

RECK_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.116428 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	189	Shared Neighborhood Hits	22
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
θ value	θ > 10 (rank : 40)	NC score	0.088957 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	158	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

TEFF2_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.055685 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	211	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.055263 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	214	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

Hits sorted by NC score

SO2B1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	37	Target Neighborhood Hits	37	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BXB6, Q8BLV8	Gene names	Slco2b1, Slc21a9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9).

SO2B1_HUMAN
NC score	0.998033 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	37	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	O94956, Q9H2Z0, Q9UFU1	Gene names	SLCO2B1, KIAA0880, OATPB, SLC21A9
Domain Architecture
Description	Solute carrier organic anion transporter family member 2B1 (Solute carrier family 21 member 9) (Organic anion transporter B) (OATP-B) (Organic anion transporter polypeptide-related protein 2) (OATP-RP2) (OATPRP2).

SO2A1_HUMAN
NC score	0.988555 (rank : 3)	θ value	1.33145e-144 (rank : 4)
Query Neighborhood Hits	37	Target Neighborhood Hits	40	Shared Neighborhood Hits	22
SwissProt Accessions	Q92959	Gene names	SLCO2A1, SLC21A2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO2A1_MOUSE
NC score	0.988053 (rank : 4)	θ value	8.33966e-147 (rank : 3)
Query Neighborhood Hits	37	Target Neighborhood Hits	51	Shared Neighborhood Hits	21
SwissProt Accessions	Q9EPT5	Gene names	Slco2a1, Slc21a2
Domain Architecture
Description	Solute carrier organic anion transporter family member 2A1 (Solute carrier family 21 member 2) (Prostaglandin transporter) (PGT).

SO3A1_HUMAN
NC score	0.974535 (rank : 5)	θ value	2.01279e-100 (rank : 5)
Query Neighborhood Hits	37	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UIG8, Q9BW73, Q9GZV2	Gene names	SLCO3A1, OATPD, SLC21A11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (Organic anion transporter polypeptide-related protein 3) (OATP-RP3) (OATPRP3) (PGE1 transporter).

SO3A1_MOUSE
NC score	0.973794 (rank : 6)	θ value	5.48135e-98 (rank : 6)
Query Neighborhood Hits	37	Target Neighborhood Hits	59	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R3L5, Q9CTV3, Q9JKV0	Gene names	Slco3a1, Oatpd, Slc21a11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (MJAM).

SO1C1_HUMAN
NC score	0.970208 (rank : 7)	θ value	8.75112e-96 (rank : 7)
Query Neighborhood Hits	37	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NYB5	Gene names	SLCO1C1, OATPF, SLC21A14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter polypeptide-related protein 5) (OAT-RP-5) (OATPRP5).

SO5A1_HUMAN
NC score	0.969993 (rank : 8)	θ value	1.54831e-84 (rank : 16)
Query Neighborhood Hits	37	Target Neighborhood Hits	57	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H2Y9	Gene names	SLCO5A1, SLC21A15
Domain Architecture
Description	Solute carrier organic anion transporter family member 5A1 (Solute carrier family 21 member 15) (Organic anion transporter polypeptide- related protein 4) (OATP-RP4) (OATPRP4).

SO1B2_MOUSE
NC score	0.968192 (rank : 9)	θ value	3.56116e-89 (rank : 11)
Query Neighborhood Hits	37	Target Neighborhood Hits	39	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JJL3, Q9JI79, Q9JJJ1	Gene names	Slco1b2, Slc21a10
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B2 (Solute carrier family 21 member 10) (Liver-specific organic anion transporter 1) (LST-1) (SLC21A6).

SO1C1_MOUSE
NC score	0.968117 (rank : 10)	θ value	2.72669e-89 (rank : 10)
Query Neighborhood Hits	37	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ERB5, Q8BX54	Gene names	Slco1c1, Oatpf, Slc21a14
Domain Architecture
Description	Solute carrier organic anion transporter family member 1C1 (Solute carrier family 21 member 14) (Organic anion transporter F) (OATP-F) (Organic anion-transporting polypeptide 14) (Organic anion transporter 2) (OATP2).

SO1B3_HUMAN
NC score	0.966281 (rank : 11)	θ value	7.42547e-87 (rank : 13)
Query Neighborhood Hits	37	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NPD5	Gene names	SLCO1B3, LST2, SLC21A8
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B3 (Solute carrier family 21 member 8) (Organic anion transporter 8) (Organic anion-transporting polypeptide 8) (OATP8) (Liver-specific organic anion transporter 2) (LST-2).

SO1A6_MOUSE
NC score	0.964860 (rank : 12)	θ value	1.03614e-88 (rank : 12)
Query Neighborhood Hits	37	Target Neighborhood Hits	34	Shared Neighborhood Hits	19
SwissProt Accessions	Q99J94, Q3UQC6, Q9CUP7	Gene names	Slco1a6, Oatp5, Slc21a13
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A6 (Solute carrier family 21 member 13) (Kidney-specific organic anion- transporting polypeptide 5) (OATP-5).

SO1B1_HUMAN
NC score	0.964006 (rank : 13)	θ value	1.00358e-83 (rank : 17)
Query Neighborhood Hits	37	Target Neighborhood Hits	43	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y6L6, Q9NQ37, Q9UBF3, Q9UH89	Gene names	SLCO1B1, LST1, OATP2, OATPC, SLC21A6
Domain Architecture
Description	Solute carrier organic anion transporter family member 1B1 (Solute carrier family 21 member 6) (Sodium-independent organic anion- transporting polypeptide 2) (OATP 2) (Liver-specific organic anion transporter 1) (LST-1) (OATP-C).

SO1A5_MOUSE
NC score	0.964006 (rank : 14)	θ value	1.26366e-94 (rank : 8)
Query Neighborhood Hits	37	Target Neighborhood Hits	31	Shared Neighborhood Hits	19
SwissProt Accessions	Q91YY5, Q91XS2	Gene names	Slco1a5, Oatp3, Slc21a7
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A5 (Solute carrier family 21 member 7) (Sodium-independent organic anion transporter 3) (Organic anion-transporting polypeptide 3).

SO1A2_HUMAN
NC score	0.962669 (rank : 15)	θ value	2.16048e-86 (rank : 14)
Query Neighborhood Hits	37	Target Neighborhood Hits	40	Shared Neighborhood Hits	19
SwissProt Accessions	P46721, Q9UGP7, Q9UL38	Gene names	SLCO1A2, OATP, SLC21A3
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A2 (Solute carrier family 21 member 3) (Sodium-independent organic anion transporter) (Organic anion-transporting polypeptide 1) (OATP1) (OATP- A).

SO1A1_MOUSE
NC score	0.962494 (rank : 16)	θ value	9.37149e-90 (rank : 9)
Query Neighborhood Hits	37	Target Neighborhood Hits	28	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXZ6	Gene names	Slco1a1, Slc21a1
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A1 (Solute carrier family 21 member 1) (Sodium-independent organic anion- transporting polypeptide 1) (OATP1).

SO1A4_MOUSE
NC score	0.961829 (rank : 17)	θ value	1.82896e-85 (rank : 15)
Query Neighborhood Hits	37	Target Neighborhood Hits	28	Shared Neighborhood Hits	19
SwissProt Accessions	Q9EP96	Gene names	Slco1a4, Oatp2, Slc21a5
Domain Architecture
Description	Solute carrier organic anion transporter family member 1A4 (Solute carrier family 21 member 5) (Sodium-independent organic anion- transporting polypeptide 2).

SO4A1_HUMAN
NC score	0.960646 (rank : 18)	θ value	4.22625e-74 (rank : 18)
Query Neighborhood Hits	37	Target Neighborhood Hits	54	Shared Neighborhood Hits	19
SwissProt Accessions	Q96BD0, Q9H4T7, Q9H4T8, Q9H8P2, Q9NWX8, Q9UI35, Q9UIG7	Gene names	SLCO4A1, OATP1, OATPE, SLC21A12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E) (Colon organic anion transporter) (Organic anion transporter polypeptide-related protein 1) (OATP-RP1) (OATPRP1) (POAT).

SO4A1_MOUSE
NC score	0.959256 (rank : 19)	θ value	5.53243e-66 (rank : 19)
Query Neighborhood Hits	37	Target Neighborhood Hits	35	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K078, Q8BZT4	Gene names	Slco4a1, Oatpe, Slc21a12
Domain Architecture
Description	Solute carrier organic anion transporter family member 4A1 (Solute carrier family 21 member 12) (Sodium-independent organic anion transporter E) (Organic anion-transporting polypeptide E) (OATP-E).

RECK_HUMAN
NC score	0.116428 (rank : 20)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	37	Target Neighborhood Hits	189	Shared Neighborhood Hits	22
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

RECK_MOUSE
NC score	0.088957 (rank : 21)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	37	Target Neighborhood Hits	158	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z0J1	Gene names	Reck
Domain Architecture	No domain graphic available
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (mRECK).

TEFF2_HUMAN
NC score	0.055685 (rank : 22)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	37	Target Neighborhood Hits	211	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
NC score	0.055263 (rank : 23)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	37	Target Neighborhood Hits	214	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

ISK3_MOUSE
NC score	0.050853 (rank : 24)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	37	Target Neighborhood Hits	36	Shared Neighborhood Hits	6
SwissProt Accessions	P09036, Q5M9M3	Gene names	Spink3
Domain Architecture
Description	Serine protease inhibitor Kazal-type 3 precursor (Prostatic secretory glycoprotein) (P12).

ARI5B_MOUSE
NC score	0.030147 (rank : 25)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	37	Target Neighborhood Hits	158	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BM75, Q8C0E0, Q8K4G8, Q8K4L9, Q9CU78, Q9JIX4	Gene names	Arid5b, Desrt, Mrf2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (MRF1-like) (Modulator recognition factor protein 2) (MRF-2) (Developmentally and sexually retarded with transient immune abnormalities protein).

KR108_HUMAN
NC score	0.028119 (rank : 26)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	37	Target Neighborhood Hits	226	Shared Neighborhood Hits	10
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

ARI5B_HUMAN
NC score	0.027645 (rank : 27)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	37	Target Neighborhood Hits	328	Shared Neighborhood Hits	4
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

KR10B_HUMAN
NC score	0.025860 (rank : 28)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	37	Target Neighborhood Hits	269	Shared Neighborhood Hits	13
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10A_HUMAN
NC score	0.019275 (rank : 29)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	37	Target Neighborhood Hits	232	Shared Neighborhood Hits	11
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR10C_HUMAN
NC score	0.016658 (rank : 30)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	37	Target Neighborhood Hits	219	Shared Neighborhood Hits	10
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

IL21R_MOUSE
NC score	0.015339 (rank : 31)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	37	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHX3, Q9ESM1	Gene names	Il21r, Nilr
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor) (Lymphocyte receptor beta) (LR-beta) (Novel cytokine receptor NR8).

PHC3_MOUSE
NC score	0.007177 (rank : 32)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	37	Target Neighborhood Hits	194	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

PHC3_HUMAN
NC score	0.006512 (rank : 33)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	37	Target Neighborhood Hits	218	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

S6A11_HUMAN
NC score	0.005647 (rank : 34)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	37	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	P48066	Gene names	SLC6A11, GABT3, GAT3
Domain Architecture
Description	Sodium- and chloride-dependent GABA transporter 3.

S6A11_MOUSE
NC score	0.004953 (rank : 35)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	37	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	P31650	Gene names	Slc6a11, Gabt4, Gat-4, Gat4
Domain Architecture	No domain graphic available
Description	Sodium- and chloride-dependent GABA transporter 4 (GAT4).

MEGF6_HUMAN
NC score	0.004398 (rank : 36)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	37	Target Neighborhood Hits	671	Shared Neighborhood Hits	12
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

JAD1A_HUMAN
NC score	0.003416 (rank : 37)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	37	Target Neighborhood Hits	328	Shared Neighborhood Hits	4
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

LRP1_HUMAN
NC score	0.002523 (rank : 38)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	37	Target Neighborhood Hits	617	Shared Neighborhood Hits	9
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LAMA1_MOUSE
NC score	0.001941 (rank : 39)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	37	Target Neighborhood Hits	838	Shared Neighborhood Hits	9
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

ANR50_HUMAN
NC score	0.000365 (rank : 40)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	37	Target Neighborhood Hits	361	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULJ7, Q6N064, Q6ZSE6	Gene names	ANKRD50, KIAA1223
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 50.

FA7_MOUSE
NC score	0.000198 (rank : 41)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	37	Target Neighborhood Hits	374	Shared Neighborhood Hits	4
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

NEB1_HUMAN
NC score	0.000109 (rank : 42)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	37	Target Neighborhood Hits	829	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).