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Network neighborhood for query Sequence : FNDC3_MOUSE

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FNDC3_MOUSE
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FNDC3_HUMAN
θ value	0 (rank : 1)	NC score	0.993146 (rank : 2)
Query Neighborhood Hits	207	Target Neighborhood Hits	196	Shared Neighborhood Hits	178
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	207	Target Neighborhood Hits	207	Shared Neighborhood Hits	207
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

TITIN_HUMAN
θ value	2.50074e-42 (rank : 3)	NC score	0.414069 (rank : 84)
Query Neighborhood Hits	207	Target Neighborhood Hits	2923	Shared Neighborhood Hits	183
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

PTPRD_HUMAN
θ value	1.6813e-30 (rank : 4)	NC score	0.629643 (rank : 24)
Query Neighborhood Hits	207	Target Neighborhood Hits	485	Shared Neighborhood Hits	174
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRD_MOUSE
θ value	1.6813e-30 (rank : 5)	NC score	0.625902 (rank : 25)
Query Neighborhood Hits	207	Target Neighborhood Hits	491	Shared Neighborhood Hits	171
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

SDK1_MOUSE
θ value	5.40856e-29 (rank : 6)	NC score	0.729848 (rank : 4)
Query Neighborhood Hits	207	Target Neighborhood Hits	495	Shared Neighborhood Hits	177
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SDK2_MOUSE
θ value	1.2049e-28 (rank : 7)	NC score	0.731309 (rank : 3)
Query Neighborhood Hits	207	Target Neighborhood Hits	480	Shared Neighborhood Hits	172
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

PTPRF_HUMAN
θ value	2.05525e-28 (rank : 8)	NC score	0.619441 (rank : 28)
Query Neighborhood Hits	207	Target Neighborhood Hits	489	Shared Neighborhood Hits	172
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

SDK2_HUMAN
θ value	5.97985e-28 (rank : 9)	NC score	0.727533 (rank : 6)
Query Neighborhood Hits	207	Target Neighborhood Hits	495	Shared Neighborhood Hits	176
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

USH2A_MOUSE
θ value	2.27234e-27 (rank : 10)	NC score	0.498883 (rank : 63)
Query Neighborhood Hits	207	Target Neighborhood Hits	626	Shared Neighborhood Hits	169
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

USH2A_HUMAN
θ value	5.06226e-27 (rank : 11)	NC score	0.515133 (rank : 61)
Query Neighborhood Hits	207	Target Neighborhood Hits	600	Shared Neighborhood Hits	168
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

SDK1_HUMAN
θ value	1.80048e-24 (rank : 12)	NC score	0.723527 (rank : 7)
Query Neighborhood Hits	207	Target Neighborhood Hits	511	Shared Neighborhood Hits	173
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

PTPRS_HUMAN
θ value	1.99067e-23 (rank : 13)	NC score	0.612165 (rank : 32)
Query Neighborhood Hits	207	Target Neighborhood Hits	472	Shared Neighborhood Hits	171
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

MYOM1_HUMAN
θ value	3.75424e-22 (rank : 14)	NC score	0.729755 (rank : 5)
Query Neighborhood Hits	207	Target Neighborhood Hits	405	Shared Neighborhood Hits	157
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

NEO1_HUMAN
θ value	1.09232e-21 (rank : 15)	NC score	0.717367 (rank : 9)
Query Neighborhood Hits	207	Target Neighborhood Hits	530	Shared Neighborhood Hits	169
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

NEO1_MOUSE
θ value	1.09232e-21 (rank : 16)	NC score	0.718727 (rank : 8)
Query Neighborhood Hits	207	Target Neighborhood Hits	523	Shared Neighborhood Hits	171
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

DSCL1_HUMAN
θ value	2.69047e-20 (rank : 17)	NC score	0.672560 (rank : 15)
Query Neighborhood Hits	207	Target Neighborhood Hits	589	Shared Neighborhood Hits	163
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

CO7A1_HUMAN
θ value	5.99374e-20 (rank : 18)	NC score	0.381366 (rank : 100)
Query Neighborhood Hits	207	Target Neighborhood Hits	807	Shared Neighborhood Hits	144
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

MYOM2_HUMAN
θ value	9.56915e-18 (rank : 19)	NC score	0.694947 (rank : 11)
Query Neighborhood Hits	207	Target Neighborhood Hits	341	Shared Neighborhood Hits	148
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

DCC_HUMAN
θ value	3.07829e-16 (rank : 20)	NC score	0.692099 (rank : 12)
Query Neighborhood Hits	207	Target Neighborhood Hits	583	Shared Neighborhood Hits	170
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

DCC_MOUSE
θ value	8.95645e-16 (rank : 21)	NC score	0.672983 (rank : 14)
Query Neighborhood Hits	207	Target Neighborhood Hits	896	Shared Neighborhood Hits	173
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

TENX_HUMAN
θ value	7.58209e-15 (rank : 22)	NC score	0.353588 (rank : 106)
Query Neighborhood Hits	207	Target Neighborhood Hits	789	Shared Neighborhood Hits	150
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

MYOM1_MOUSE
θ value	9.90251e-15 (rank : 23)	NC score	0.695796 (rank : 10)
Query Neighborhood Hits	207	Target Neighborhood Hits	415	Shared Neighborhood Hits	168
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

FINC_MOUSE
θ value	1.68911e-14 (rank : 24)	NC score	0.677166 (rank : 13)
Query Neighborhood Hits	207	Target Neighborhood Hits	309	Shared Neighborhood Hits	155
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

CHL1_MOUSE
θ value	3.18553e-13 (rank : 25)	NC score	0.616416 (rank : 30)
Query Neighborhood Hits	207	Target Neighborhood Hits	402	Shared Neighborhood Hits	141
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

NRCAM_HUMAN
θ value	1.2105e-12 (rank : 26)	NC score	0.661786 (rank : 17)
Query Neighborhood Hits	207	Target Neighborhood Hits	439	Shared Neighborhood Hits	160
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

CNTN3_HUMAN
θ value	3.52202e-12 (rank : 27)	NC score	0.625407 (rank : 26)
Query Neighborhood Hits	207	Target Neighborhood Hits	455	Shared Neighborhood Hits	156
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

L1CAM_HUMAN
θ value	4.59992e-12 (rank : 28)	NC score	0.652551 (rank : 19)
Query Neighborhood Hits	207	Target Neighborhood Hits	457	Shared Neighborhood Hits	166
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

MYPC3_MOUSE
θ value	4.59992e-12 (rank : 29)	NC score	0.578949 (rank : 43)
Query Neighborhood Hits	207	Target Neighborhood Hits	310	Shared Neighborhood Hits	129
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

L1CAM_MOUSE
θ value	7.84624e-12 (rank : 30)	NC score	0.641591 (rank : 21)
Query Neighborhood Hits	207	Target Neighborhood Hits	457	Shared Neighborhood Hits	165
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

MYPC3_HUMAN
θ value	7.84624e-12 (rank : 31)	NC score	0.581467 (rank : 42)
Query Neighborhood Hits	207	Target Neighborhood Hits	318	Shared Neighborhood Hits	129
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

DSCAM_HUMAN
θ value	1.74796e-11 (rank : 32)	NC score	0.653714 (rank : 18)
Query Neighborhood Hits	207	Target Neighborhood Hits	524	Shared Neighborhood Hits	159
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

FINC_HUMAN
θ value	1.74796e-11 (rank : 33)	NC score	0.666176 (rank : 16)
Query Neighborhood Hits	207	Target Neighborhood Hits	302	Shared Neighborhood Hits	162
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

MYPC2_HUMAN
θ value	8.67504e-11 (rank : 34)	NC score	0.567960 (rank : 52)
Query Neighborhood Hits	207	Target Neighborhood Hits	316	Shared Neighborhood Hits	122
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

NRCAM_MOUSE
θ value	8.67504e-11 (rank : 35)	NC score	0.650225 (rank : 20)
Query Neighborhood Hits	207	Target Neighborhood Hits	432	Shared Neighborhood Hits	159
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

CNTN2_HUMAN
θ value	1.133e-10 (rank : 36)	NC score	0.617451 (rank : 29)
Query Neighborhood Hits	207	Target Neighborhood Hits	440	Shared Neighborhood Hits	158
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

NCAM2_MOUSE
θ value	1.133e-10 (rank : 37)	NC score	0.535887 (rank : 59)
Query Neighborhood Hits	207	Target Neighborhood Hits	472	Shared Neighborhood Hits	147
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

MYPC2_MOUSE
θ value	1.9326e-10 (rank : 38)	NC score	0.577290 (rank : 45)
Query Neighborhood Hits	207	Target Neighborhood Hits	297	Shared Neighborhood Hits	116
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

NCAM2_HUMAN
θ value	1.9326e-10 (rank : 39)	NC score	0.528061 (rank : 60)
Query Neighborhood Hits	207	Target Neighborhood Hits	441	Shared Neighborhood Hits	145
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

TENR_HUMAN
θ value	1.9326e-10 (rank : 40)	NC score	0.432970 (rank : 79)
Query Neighborhood Hits	207	Target Neighborhood Hits	526	Shared Neighborhood Hits	142
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

CNTN1_MOUSE
θ value	2.52405e-10 (rank : 41)	NC score	0.608300 (rank : 34)
Query Neighborhood Hits	207	Target Neighborhood Hits	422	Shared Neighborhood Hits	148
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

TENA_MOUSE
θ value	2.52405e-10 (rank : 42)	NC score	0.326743 (rank : 122)
Query Neighborhood Hits	207	Target Neighborhood Hits	596	Shared Neighborhood Hits	133
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENN_HUMAN
θ value	3.29651e-10 (rank : 43)	NC score	0.402380 (rank : 90)
Query Neighborhood Hits	207	Target Neighborhood Hits	453	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

CNTN4_MOUSE
θ value	4.30538e-10 (rank : 44)	NC score	0.597240 (rank : 40)
Query Neighborhood Hits	207	Target Neighborhood Hits	445	Shared Neighborhood Hits	145
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

ROBO1_MOUSE
θ value	4.30538e-10 (rank : 45)	NC score	0.568381 (rank : 51)
Query Neighborhood Hits	207	Target Neighborhood Hits	559	Shared Neighborhood Hits	155
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

CHL1_HUMAN
θ value	5.62301e-10 (rank : 46)	NC score	0.632864 (rank : 22)
Query Neighborhood Hits	207	Target Neighborhood Hits	413	Shared Neighborhood Hits	145
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

TENR_MOUSE
θ value	5.62301e-10 (rank : 47)	NC score	0.423089 (rank : 81)
Query Neighborhood Hits	207	Target Neighborhood Hits	531	Shared Neighborhood Hits	139
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

SORL_HUMAN
θ value	1.25267e-09 (rank : 48)	NC score	0.299226 (rank : 151)
Query Neighborhood Hits	207	Target Neighborhood Hits	440	Shared Neighborhood Hits	124
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

CNTN1_HUMAN
θ value	1.63604e-09 (rank : 49)	NC score	0.607467 (rank : 35)
Query Neighborhood Hits	207	Target Neighborhood Hits	431	Shared Neighborhood Hits	148
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

ROBO3_HUMAN
θ value	2.13673e-09 (rank : 50)	NC score	0.578724 (rank : 44)
Query Neighborhood Hits	207	Target Neighborhood Hits	570	Shared Neighborhood Hits	154
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

COCA1_HUMAN
θ value	2.79066e-09 (rank : 51)	NC score	0.496848 (rank : 64)
Query Neighborhood Hits	207	Target Neighborhood Hits	458	Shared Neighborhood Hits	149
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

CNTN2_MOUSE
θ value	3.64472e-09 (rank : 52)	NC score	0.615022 (rank : 31)
Query Neighborhood Hits	207	Target Neighborhood Hits	450	Shared Neighborhood Hits	157
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CNTN4_HUMAN
θ value	3.64472e-09 (rank : 53)	NC score	0.597257 (rank : 39)
Query Neighborhood Hits	207	Target Neighborhood Hits	449	Shared Neighborhood Hits	146
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

PTPRM_HUMAN
θ value	3.64472e-09 (rank : 54)	NC score	0.402934 (rank : 89)
Query Neighborhood Hits	207	Target Neighborhood Hits	244	Shared Neighborhood Hits	132
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	4.76016e-09 (rank : 55)	NC score	0.398994 (rank : 92)
Query Neighborhood Hits	207	Target Neighborhood Hits	238	Shared Neighborhood Hits	132
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

DUET_HUMAN
θ value	8.11959e-09 (rank : 56)	NC score	0.220177 (rank : 237)
Query Neighborhood Hits	207	Target Neighborhood Hits	1220	Shared Neighborhood Hits	138
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

NFASC_HUMAN
θ value	8.11959e-09 (rank : 57)	NC score	0.632252 (rank : 23)
Query Neighborhood Hits	207	Target Neighborhood Hits	497	Shared Neighborhood Hits	159
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

COCA1_MOUSE
θ value	1.06045e-08 (rank : 58)	NC score	0.509387 (rank : 62)
Query Neighborhood Hits	207	Target Neighborhood Hits	467	Shared Neighborhood Hits	155
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

EPHA2_HUMAN
θ value	1.06045e-08 (rank : 59)	NC score	0.218930 (rank : 239)
Query Neighborhood Hits	207	Target Neighborhood Hits	1021	Shared Neighborhood Hits	134
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

CNTN3_MOUSE
θ value	1.38499e-08 (rank : 60)	NC score	0.623926 (rank : 27)
Query Neighborhood Hits	207	Target Neighborhood Hits	447	Shared Neighborhood Hits	157
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

ROBO1_HUMAN
θ value	1.80886e-08 (rank : 61)	NC score	0.556292 (rank : 53)
Query Neighborhood Hits	207	Target Neighborhood Hits	529	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

CNTN5_MOUSE
θ value	3.08544e-08 (rank : 62)	NC score	0.600407 (rank : 38)
Query Neighborhood Hits	207	Target Neighborhood Hits	434	Shared Neighborhood Hits	147
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

CNTN5_HUMAN
θ value	4.0297e-08 (rank : 63)	NC score	0.608478 (rank : 33)
Query Neighborhood Hits	207	Target Neighborhood Hits	446	Shared Neighborhood Hits	155
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

EPHA2_MOUSE
θ value	4.0297e-08 (rank : 64)	NC score	0.212502 (rank : 248)
Query Neighborhood Hits	207	Target Neighborhood Hits	1020	Shared Neighborhood Hits	128
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

PTPRT_HUMAN
θ value	4.0297e-08 (rank : 65)	NC score	0.376148 (rank : 102)
Query Neighborhood Hits	207	Target Neighborhood Hits	217	Shared Neighborhood Hits	122
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	4.0297e-08 (rank : 66)	NC score	0.376782 (rank : 101)
Query Neighborhood Hits	207	Target Neighborhood Hits	219	Shared Neighborhood Hits	122
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

TENA_HUMAN
θ value	4.0297e-08 (rank : 67)	NC score	0.340903 (rank : 114)
Query Neighborhood Hits	207	Target Neighborhood Hits	631	Shared Neighborhood Hits	142
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

CNTN6_MOUSE
θ value	5.26297e-08 (rank : 68)	NC score	0.596669 (rank : 41)
Query Neighborhood Hits	207	Target Neighborhood Hits	429	Shared Neighborhood Hits	141
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

ROBO2_HUMAN
θ value	5.26297e-08 (rank : 69)	NC score	0.576365 (rank : 47)
Query Neighborhood Hits	207	Target Neighborhood Hits	479	Shared Neighborhood Hits	155
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ITB4_HUMAN
θ value	1.17247e-07 (rank : 70)	NC score	0.451957 (rank : 73)
Query Neighborhood Hits	207	Target Neighborhood Hits	458	Shared Neighborhood Hits	147
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

TIE1_HUMAN
θ value	1.17247e-07 (rank : 71)	NC score	0.231718 (rank : 224)
Query Neighborhood Hits	207	Target Neighborhood Hits	1241	Shared Neighborhood Hits	151
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

COEA1_MOUSE
θ value	1.53129e-07 (rank : 72)	NC score	0.441836 (rank : 77)
Query Neighborhood Hits	207	Target Neighborhood Hits	402	Shared Neighborhood Hits	107
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

CNTN6_HUMAN
θ value	2.61198e-07 (rank : 73)	NC score	0.603100 (rank : 37)
Query Neighborhood Hits	207	Target Neighborhood Hits	422	Shared Neighborhood Hits	143
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

BOC_MOUSE
θ value	3.41135e-07 (rank : 74)	NC score	0.538113 (rank : 58)
Query Neighborhood Hits	207	Target Neighborhood Hits	433	Shared Neighborhood Hits	130
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

CDON_MOUSE
θ value	3.41135e-07 (rank : 75)	NC score	0.552041 (rank : 54)
Query Neighborhood Hits	207	Target Neighborhood Hits	410	Shared Neighborhood Hits	134
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

PUNC_MOUSE
θ value	3.41135e-07 (rank : 76)	NC score	0.572849 (rank : 49)
Query Neighborhood Hits	207	Target Neighborhood Hits	501	Shared Neighborhood Hits	137
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

ROBO2_MOUSE
θ value	3.41135e-07 (rank : 77)	NC score	0.573838 (rank : 48)
Query Neighborhood Hits	207	Target Neighborhood Hits	504	Shared Neighborhood Hits	161
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

EPHB4_HUMAN
θ value	4.45536e-07 (rank : 78)	NC score	0.230036 (rank : 226)
Query Neighborhood Hits	207	Target Neighborhood Hits	1056	Shared Neighborhood Hits	145
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

SORL_MOUSE
θ value	4.45536e-07 (rank : 79)	NC score	0.287135 (rank : 164)
Query Neighborhood Hits	207	Target Neighborhood Hits	439	Shared Neighborhood Hits	119
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

COEA1_HUMAN
θ value	5.81887e-07 (rank : 80)	NC score	0.397641 (rank : 94)
Query Neighborhood Hits	207	Target Neighborhood Hits	427	Shared Neighborhood Hits	122
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

EPHB4_MOUSE
θ value	7.59969e-07 (rank : 81)	NC score	0.233984 (rank : 219)
Query Neighborhood Hits	207	Target Neighborhood Hits	1013	Shared Neighborhood Hits	145
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

BOC_HUMAN
θ value	9.92553e-07 (rank : 82)	NC score	0.543641 (rank : 56)
Query Neighborhood Hits	207	Target Neighborhood Hits	543	Shared Neighborhood Hits	139
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

CDON_HUMAN
θ value	9.92553e-07 (rank : 83)	NC score	0.551753 (rank : 55)
Query Neighborhood Hits	207	Target Neighborhood Hits	412	Shared Neighborhood Hits	134
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

MYLK_HUMAN
θ value	9.92553e-07 (rank : 84)	NC score	0.257464 (rank : 194)
Query Neighborhood Hits	207	Target Neighborhood Hits	1328	Shared Neighborhood Hits	138
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

MYLK_MOUSE
θ value	1.69304e-06 (rank : 85)	NC score	0.255859 (rank : 196)
Query Neighborhood Hits	207	Target Neighborhood Hits	1489	Shared Neighborhood Hits	141
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

ROBO3_MOUSE
θ value	1.69304e-06 (rank : 86)	NC score	0.569709 (rank : 50)
Query Neighborhood Hits	207	Target Neighborhood Hits	524	Shared Neighborhood Hits	149
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

EPHA3_MOUSE
θ value	2.21117e-06 (rank : 87)	NC score	0.238502 (rank : 214)
Query Neighborhood Hits	207	Target Neighborhood Hits	1009	Shared Neighborhood Hits	147
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

TIE2_MOUSE
θ value	2.21117e-06 (rank : 88)	NC score	0.228829 (rank : 229)
Query Neighborhood Hits	207	Target Neighborhood Hits	1204	Shared Neighborhood Hits	147
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

OBSCN_HUMAN
θ value	2.88788e-06 (rank : 89)	NC score	0.253210 (rank : 198)
Query Neighborhood Hits	207	Target Neighborhood Hits	1931	Shared Neighborhood Hits	145
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

TENN_MOUSE
θ value	2.88788e-06 (rank : 90)	NC score	0.427727 (rank : 80)
Query Neighborhood Hits	207	Target Neighborhood Hits	484	Shared Neighborhood Hits	137
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

MYPC1_HUMAN
θ value	4.92598e-06 (rank : 91)	NC score	0.539248 (rank : 57)
Query Neighborhood Hits	207	Target Neighborhood Hits	303	Shared Neighborhood Hits	117
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

NFASC_MOUSE
θ value	4.92598e-06 (rank : 92)	NC score	0.604793 (rank : 36)
Query Neighborhood Hits	207	Target Neighborhood Hits	475	Shared Neighborhood Hits	151
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

ROS_HUMAN
θ value	4.92598e-06 (rank : 93)	NC score	0.215906 (rank : 243)
Query Neighborhood Hits	207	Target Neighborhood Hits	907	Shared Neighborhood Hits	150
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

EPHA5_HUMAN
θ value	6.43352e-06 (rank : 94)	NC score	0.232448 (rank : 221)
Query Neighborhood Hits	207	Target Neighborhood Hits	1009	Shared Neighborhood Hits	150
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

PUNC_HUMAN
θ value	6.43352e-06 (rank : 95)	NC score	0.576686 (rank : 46)
Query Neighborhood Hits	207	Target Neighborhood Hits	449	Shared Neighborhood Hits	142
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

TIE2_HUMAN
θ value	6.43352e-06 (rank : 96)	NC score	0.229090 (rank : 228)
Query Neighborhood Hits	207	Target Neighborhood Hits	1192	Shared Neighborhood Hits	149
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

EPHA3_HUMAN
θ value	1.87187e-05 (rank : 97)	NC score	0.231850 (rank : 223)
Query Neighborhood Hits	207	Target Neighborhood Hits	1005	Shared Neighborhood Hits	146
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

EPHA7_HUMAN
θ value	3.19293e-05 (rank : 98)	NC score	0.245789 (rank : 205)
Query Neighborhood Hits	207	Target Neighborhood Hits	1053	Shared Neighborhood Hits	148
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

EPHA8_HUMAN
θ value	3.19293e-05 (rank : 99)	NC score	0.237665 (rank : 215)
Query Neighborhood Hits	207	Target Neighborhood Hits	956	Shared Neighborhood Hits	143
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

EPHA7_MOUSE
θ value	5.44631e-05 (rank : 100)	NC score	0.244806 (rank : 206)
Query Neighborhood Hits	207	Target Neighborhood Hits	1025	Shared Neighborhood Hits	148
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

PTPRK_HUMAN
θ value	5.44631e-05 (rank : 101)	NC score	0.331805 (rank : 118)
Query Neighborhood Hits	207	Target Neighborhood Hits	228	Shared Neighborhood Hits	116
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

TRIM9_MOUSE
θ value	5.44631e-05 (rank : 102)	NC score	0.140617 (rank : 360)
Query Neighborhood Hits	207	Target Neighborhood Hits	274	Shared Neighborhood Hits	53
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

EPHA8_MOUSE
θ value	7.1131e-05 (rank : 103)	NC score	0.239978 (rank : 210)
Query Neighborhood Hits	207	Target Neighborhood Hits	969	Shared Neighborhood Hits	144
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

TIE1_MOUSE
θ value	9.29e-05 (rank : 104)	NC score	0.235592 (rank : 217)
Query Neighborhood Hits	207	Target Neighborhood Hits	1266	Shared Neighborhood Hits	151
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

PTPRK_MOUSE
θ value	0.000121331 (rank : 105)	NC score	0.334916 (rank : 116)
Query Neighborhood Hits	207	Target Neighborhood Hits	223	Shared Neighborhood Hits	114
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

HCFC1_MOUSE
θ value	0.000158464 (rank : 106)	NC score	0.213871 (rank : 246)
Query Neighborhood Hits	207	Target Neighborhood Hits	348	Shared Neighborhood Hits	65
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

TRIM9_HUMAN
θ value	0.000158464 (rank : 107)	NC score	0.144005 (rank : 355)
Query Neighborhood Hits	207	Target Neighborhood Hits	294	Shared Neighborhood Hits	56
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

EPHA4_MOUSE
θ value	0.000270298 (rank : 108)	NC score	0.241673 (rank : 208)
Query Neighborhood Hits	207	Target Neighborhood Hits	982	Shared Neighborhood Hits	149
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

EPHA1_HUMAN
θ value	0.00035302 (rank : 109)	NC score	0.179690 (rank : 281)
Query Neighborhood Hits	207	Target Neighborhood Hits	997	Shared Neighborhood Hits	104
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

MERTK_HUMAN
θ value	0.00035302 (rank : 110)	NC score	0.241631 (rank : 209)
Query Neighborhood Hits	207	Target Neighborhood Hits	988	Shared Neighborhood Hits	125
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

MERTK_MOUSE
θ value	0.00035302 (rank : 111)	NC score	0.239134 (rank : 211)
Query Neighborhood Hits	207	Target Neighborhood Hits	974	Shared Neighborhood Hits	129
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

EPHA5_MOUSE
θ value	0.000461057 (rank : 112)	NC score	0.198792 (rank : 261)
Query Neighborhood Hits	207	Target Neighborhood Hits	950	Shared Neighborhood Hits	137
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

NCA12_HUMAN
θ value	0.000461057 (rank : 113)	NC score	0.472265 (rank : 68)
Query Neighborhood Hits	207	Target Neighborhood Hits	437	Shared Neighborhood Hits	124
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

EPHA4_HUMAN
θ value	0.000602161 (rank : 114)	NC score	0.238812 (rank : 212)
Query Neighborhood Hits	207	Target Neighborhood Hits	975	Shared Neighborhood Hits	146
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

CSF3R_HUMAN
θ value	0.000786445 (rank : 115)	NC score	0.348543 (rank : 108)
Query Neighborhood Hits	207	Target Neighborhood Hits	140	Shared Neighborhood Hits	95
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

HCFC1_HUMAN
θ value	0.000786445 (rank : 116)	NC score	0.186573 (rank : 274)
Query Neighborhood Hits	207	Target Neighborhood Hits	331	Shared Neighborhood Hits	52
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

HCFC2_HUMAN
θ value	0.000786445 (rank : 117)	NC score	0.290424 (rank : 162)
Query Neighborhood Hits	207	Target Neighborhood Hits	154	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

EPHB3_MOUSE
θ value	0.00102713 (rank : 118)	NC score	0.238789 (rank : 213)
Query Neighborhood Hits	207	Target Neighborhood Hits	996	Shared Neighborhood Hits	144
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

NCA11_HUMAN
θ value	0.00102713 (rank : 119)	NC score	0.486895 (rank : 65)
Query Neighborhood Hits	207	Target Neighborhood Hits	443	Shared Neighborhood Hits	130
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

NCA11_MOUSE
θ value	0.00102713 (rank : 120)	NC score	0.475449 (rank : 67)
Query Neighborhood Hits	207	Target Neighborhood Hits	661	Shared Neighborhood Hits	127
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

PTPRB_HUMAN
θ value	0.00102713 (rank : 121)	NC score	0.320930 (rank : 130)
Query Neighborhood Hits	207	Target Neighborhood Hits	242	Shared Neighborhood Hits	103
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

TYRO3_MOUSE
θ value	0.00102713 (rank : 122)	NC score	0.256325 (rank : 195)
Query Neighborhood Hits	207	Target Neighborhood Hits	1007	Shared Neighborhood Hits	138
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

HCFC2_MOUSE
θ value	0.00134147 (rank : 123)	NC score	0.417322 (rank : 82)
Query Neighborhood Hits	207	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

PTPRJ_MOUSE
θ value	0.00134147 (rank : 124)	NC score	0.271908 (rank : 177)
Query Neighborhood Hits	207	Target Neighborhood Hits	188	Shared Neighborhood Hits	85
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

TYRO3_HUMAN
θ value	0.00134147 (rank : 125)	NC score	0.260046 (rank : 190)
Query Neighborhood Hits	207	Target Neighborhood Hits	995	Shared Neighborhood Hits	135
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

EPHA1_MOUSE
θ value	0.00298849 (rank : 126)	NC score	0.180352 (rank : 280)
Query Neighborhood Hits	207	Target Neighborhood Hits	958	Shared Neighborhood Hits	111
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

RIMB2_HUMAN
θ value	0.00298849 (rank : 127)	NC score	0.216010 (rank : 242)
Query Neighborhood Hits	207	Target Neighborhood Hits	263	Shared Neighborhood Hits	59
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

TARSH_HUMAN
θ value	0.00298849 (rank : 128)	NC score	0.299031 (rank : 152)
Query Neighborhood Hits	207	Target Neighborhood Hits	768	Shared Neighborhood Hits	109
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

MYBPH_MOUSE
θ value	0.00390308 (rank : 129)	NC score	0.484023 (rank : 66)
Query Neighborhood Hits	207	Target Neighborhood Hits	290	Shared Neighborhood Hits	110
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

LIFR_MOUSE
θ value	0.00509761 (rank : 130)	NC score	0.389282 (rank : 98)
Query Neighborhood Hits	207	Target Neighborhood Hits	127	Shared Neighborhood Hits	87
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

COKA1_HUMAN
θ value	0.00665767 (rank : 131)	NC score	0.375092 (rank : 103)
Query Neighborhood Hits	207	Target Neighborhood Hits	403	Shared Neighborhood Hits	113
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

EPHA6_HUMAN
θ value	0.0113563 (rank : 132)	NC score	0.217781 (rank : 240)
Query Neighborhood Hits	207	Target Neighborhood Hits	959	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHA6_MOUSE
θ value	0.0113563 (rank : 133)	NC score	0.208800 (rank : 253)
Query Neighborhood Hits	207	Target Neighborhood Hits	946	Shared Neighborhood Hits	117
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHB2_HUMAN
θ value	0.0113563 (rank : 134)	NC score	0.223204 (rank : 233)
Query Neighborhood Hits	207	Target Neighborhood Hits	983	Shared Neighborhood Hits	139
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

EPHB2_MOUSE
θ value	0.0113563 (rank : 135)	NC score	0.223263 (rank : 232)
Query Neighborhood Hits	207	Target Neighborhood Hits	982	Shared Neighborhood Hits	139
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

IGF1R_HUMAN
θ value	0.0148317 (rank : 136)	NC score	0.165644 (rank : 308)
Query Neighborhood Hits	207	Target Neighborhood Hits	977	Shared Neighborhood Hits	104
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IL6RB_MOUSE
θ value	0.0148317 (rank : 137)	NC score	0.409812 (rank : 88)
Query Neighborhood Hits	207	Target Neighborhood Hits	168	Shared Neighborhood Hits	121
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

EPHB6_MOUSE
θ value	0.0193708 (rank : 138)	NC score	0.248396 (rank : 204)
Query Neighborhood Hits	207	Target Neighborhood Hits	906	Shared Neighborhood Hits	134
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

EPHAA_HUMAN
θ value	0.0252991 (rank : 139)	NC score	0.206668 (rank : 254)
Query Neighborhood Hits	207	Target Neighborhood Hits	960	Shared Neighborhood Hits	118
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

FANK1_HUMAN
θ value	0.0252991 (rank : 140)	NC score	0.060334 (rank : 708)
Query Neighborhood Hits	207	Target Neighborhood Hits	326	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

INSRR_HUMAN
θ value	0.0252991 (rank : 141)	NC score	0.170428 (rank : 297)
Query Neighborhood Hits	207	Target Neighborhood Hits	950	Shared Neighborhood Hits	104
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

MYBPH_HUMAN
θ value	0.0252991 (rank : 142)	NC score	0.465922 (rank : 70)
Query Neighborhood Hits	207	Target Neighborhood Hits	256	Shared Neighborhood Hits	106
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

IGF1R_MOUSE
θ value	0.0330416 (rank : 143)	NC score	0.163400 (rank : 312)
Query Neighborhood Hits	207	Target Neighborhood Hits	973	Shared Neighborhood Hits	103
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

INSRR_MOUSE
θ value	0.0431538 (rank : 144)	NC score	0.168985 (rank : 302)
Query Neighborhood Hits	207	Target Neighborhood Hits	961	Shared Neighborhood Hits	103
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

LIFR_HUMAN
θ value	0.0431538 (rank : 145)	NC score	0.390008 (rank : 97)
Query Neighborhood Hits	207	Target Neighborhood Hits	130	Shared Neighborhood Hits	88
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

NPHN_HUMAN
θ value	0.0431538 (rank : 146)	NC score	0.462354 (rank : 71)
Query Neighborhood Hits	207	Target Neighborhood Hits	362	Shared Neighborhood Hits	114
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

UFO_MOUSE
θ value	0.0431538 (rank : 147)	NC score	0.226436 (rank : 231)
Query Neighborhood Hits	207	Target Neighborhood Hits	988	Shared Neighborhood Hits	138
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

EPHB3_HUMAN
θ value	0.0563607 (rank : 148)	NC score	0.235769 (rank : 216)
Query Neighborhood Hits	207	Target Neighborhood Hits	996	Shared Neighborhood Hits	145
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

FANK1_MOUSE
θ value	0.0563607 (rank : 149)	NC score	0.060544 (rank : 704)
Query Neighborhood Hits	207	Target Neighborhood Hits	325	Shared Neighborhood Hits	43
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

ANKF1_HUMAN
θ value	0.0736092 (rank : 150)	NC score	0.211073 (rank : 249)
Query Neighborhood Hits	207	Target Neighborhood Hits	126	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

IL6RB_HUMAN
θ value	0.0736092 (rank : 151)	NC score	0.453224 (rank : 72)
Query Neighborhood Hits	207	Target Neighborhood Hits	181	Shared Neighborhood Hits	124
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

NCA12_MOUSE
θ value	0.0736092 (rank : 152)	NC score	0.469640 (rank : 69)
Query Neighborhood Hits	207	Target Neighborhood Hits	399	Shared Neighborhood Hits	114
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

EPHB6_HUMAN
θ value	0.0961366 (rank : 153)	NC score	0.252542 (rank : 200)
Query Neighborhood Hits	207	Target Neighborhood Hits	912	Shared Neighborhood Hits	138
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

UFO_HUMAN
θ value	0.0961366 (rank : 154)	NC score	0.220673 (rank : 235)
Query Neighborhood Hits	207	Target Neighborhood Hits	981	Shared Neighborhood Hits	136
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

NPHN_MOUSE
θ value	0.163984 (rank : 155)	NC score	0.441263 (rank : 78)
Query Neighborhood Hits	207	Target Neighborhood Hits	370	Shared Neighborhood Hits	119
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

INSR_MOUSE
θ value	0.21417 (rank : 156)	NC score	0.164573 (rank : 311)
Query Neighborhood Hits	207	Target Neighborhood Hits	968	Shared Neighborhood Hits	107
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

INSR_HUMAN
θ value	0.279714 (rank : 157)	NC score	0.159961 (rank : 317)
Query Neighborhood Hits	207	Target Neighborhood Hits	963	Shared Neighborhood Hits	103
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

TRI42_HUMAN
θ value	0.279714 (rank : 158)	NC score	0.089026 (rank : 516)
Query Neighborhood Hits	207	Target Neighborhood Hits	283	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

PTPRJ_HUMAN
θ value	0.47712 (rank : 159)	NC score	0.263166 (rank : 187)
Query Neighborhood Hits	207	Target Neighborhood Hits	207	Shared Neighborhood Hits	96
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

EPHB1_HUMAN
θ value	0.62314 (rank : 160)	NC score	0.215011 (rank : 244)
Query Neighborhood Hits	207	Target Neighborhood Hits	988	Shared Neighborhood Hits	136
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

K0195_HUMAN
θ value	0.62314 (rank : 161)	NC score	0.043783 (rank : 861)
Query Neighborhood Hits	207	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	Q12767, O75536, Q86XF1	Gene names	KIAA0195, TMEM94
Domain Architecture	No domain graphic available
Description	Protein KIAA0195 (Transmembrane protein 94).

K0195_MOUSE
θ value	0.62314 (rank : 162)	NC score	0.040737 (rank : 862)
Query Neighborhood Hits	207	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TSH8, Q80U66, Q8BL05, Q8K0Q0, Q91VY1	Gene names	Kiaa0195
Domain Architecture	No domain graphic available
Description	Protein KIAA0195.

CT195_MOUSE
θ value	0.813845 (rank : 163)	NC score	0.057272 (rank : 738)
Query Neighborhood Hits	207	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q80WB0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf195 homolog.

SPEG_MOUSE
θ value	0.813845 (rank : 164)	NC score	0.234870 (rank : 218)
Query Neighborhood Hits	207	Target Neighborhood Hits	1959	Shared Neighborhood Hits	133
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TRIM1_MOUSE
θ value	0.813845 (rank : 165)	NC score	0.062905 (rank : 677)
Query Neighborhood Hits	207	Target Neighborhood Hits	361	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

FLRT3_HUMAN
θ value	1.06291 (rank : 166)	NC score	0.021268 (rank : 869)
Query Neighborhood Hits	207	Target Neighborhood Hits	281	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZU0, Q96K39, Q96K42, Q96KB1, Q9P259	Gene names	FLRT3, KIAA1469
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT3 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 3).

XYLB_MOUSE
θ value	1.06291 (rank : 167)	NC score	0.034726 (rank : 864)
Query Neighborhood Hits	207	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q3TNA1, Q8R156	Gene names	Xylb
Domain Architecture	No domain graphic available
Description	Xylulose kinase (EC 2.7.1.17) (Xylulokinase).

KALM_HUMAN
θ value	1.38821 (rank : 168)	NC score	0.352517 (rank : 107)
Query Neighborhood Hits	207	Target Neighborhood Hits	114	Shared Neighborhood Hits	77
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

TSH3_HUMAN
θ value	1.38821 (rank : 169)	NC score	0.011188 (rank : 874)
Query Neighborhood Hits	207	Target Neighborhood Hits	564	Shared Neighborhood Hits	6
SwissProt Accessions	Q63HK5, Q9H0G6, Q9P254	Gene names	TSHZ3, KIAA1474, TSH3, ZNF537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

SPEG_HUMAN
θ value	2.36792 (rank : 170)	NC score	0.232014 (rank : 222)
Query Neighborhood Hits	207	Target Neighborhood Hits	1762	Shared Neighborhood Hits	131
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TRI46_HUMAN
θ value	2.36792 (rank : 171)	NC score	0.050771 (rank : 840)
Query Neighborhood Hits	207	Target Neighborhood Hits	291	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

TRI46_MOUSE
θ value	2.36792 (rank : 172)	NC score	0.051725 (rank : 823)
Query Neighborhood Hits	207	Target Neighborhood Hits	287	Shared Neighborhood Hits	30
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

COIA1_MOUSE
θ value	3.0926 (rank : 173)	NC score	0.038432 (rank : 863)
Query Neighborhood Hits	207	Target Neighborhood Hits	481	Shared Neighborhood Hits	12
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CT075_HUMAN
θ value	3.0926 (rank : 174)	NC score	0.155731 (rank : 326)
Query Neighborhood Hits	207	Target Neighborhood Hits	387	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

K0586_HUMAN
θ value	3.0926 (rank : 175)	NC score	0.018840 (rank : 870)
Query Neighborhood Hits	207	Target Neighborhood Hits	311	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

TSH3_MOUSE
θ value	3.0926 (rank : 176)	NC score	0.009593 (rank : 877)
Query Neighborhood Hits	207	Target Neighborhood Hits	590	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

CD45_HUMAN
θ value	4.03905 (rank : 177)	NC score	0.187420 (rank : 273)
Query Neighborhood Hits	207	Target Neighborhood Hits	243	Shared Neighborhood Hits	58
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

I12R2_MOUSE
θ value	4.03905 (rank : 178)	NC score	0.360633 (rank : 105)
Query Neighborhood Hits	207	Target Neighborhood Hits	143	Shared Neighborhood Hits	104
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

LBR_HUMAN
θ value	4.03905 (rank : 179)	NC score	0.009045 (rank : 878)
Query Neighborhood Hits	207	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q14739, Q14740, Q53GU7, Q59FE6	Gene names	LBR
Domain Architecture
Description	Lamin-B receptor (Integral nuclear envelope inner membrane protein) (LMN2R).

NBR1_HUMAN
θ value	4.03905 (rank : 180)	NC score	0.014469 (rank : 873)
Query Neighborhood Hits	207	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	Q14596, Q13173, Q15026, Q96GB6, Q9NRF7	Gene names	NBR1, 1A13B, KIAA0049, M17S2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2) (1A1-3B).

NFRKB_HUMAN
θ value	4.03905 (rank : 181)	NC score	0.016020 (rank : 872)
Query Neighborhood Hits	207	Target Neighborhood Hits	211	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

RFX2_HUMAN
θ value	4.03905 (rank : 182)	NC score	0.006897 (rank : 881)
Query Neighborhood Hits	207	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P48378	Gene names	RFX2
Domain Architecture
Description	DNA-binding protein RFX2.

SMCA5_MOUSE
θ value	4.03905 (rank : 183)	NC score	0.002175 (rank : 886)
Query Neighborhood Hits	207	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

TR19L_HUMAN
θ value	4.03905 (rank : 184)	NC score	0.023544 (rank : 868)
Query Neighborhood Hits	207	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

AL3A1_HUMAN
θ value	5.27518 (rank : 185)	NC score	0.003354 (rank : 884)
Query Neighborhood Hits	207	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P30838, Q9BT37	Gene names	ALDH3A1, ALDH3
Domain Architecture
Description	Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (ALDH class 3) (ALDHIII).

CDX1_MOUSE
θ value	5.27518 (rank : 186)	NC score	-0.001769 (rank : 888)
Query Neighborhood Hits	207	Target Neighborhood Hits	379	Shared Neighborhood Hits	4
SwissProt Accessions	P18111, Q8VCF7	Gene names	Cdx1, Cdx-1
Domain Architecture
Description	Homeobox protein CDX-1 (Caudal-type homeobox protein 1).

CT075_MOUSE
θ value	5.27518 (rank : 187)	NC score	0.115189 (rank : 403)
Query Neighborhood Hits	207	Target Neighborhood Hits	358	Shared Neighborhood Hits	58
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

DAB2_MOUSE
θ value	5.27518 (rank : 188)	NC score	0.007334 (rank : 880)
Query Neighborhood Hits	207	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

PTPRU_HUMAN
θ value	5.27518 (rank : 189)	NC score	0.343659 (rank : 112)
Query Neighborhood Hits	207	Target Neighborhood Hits	237	Shared Neighborhood Hits	129
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

TREF1_HUMAN
θ value	5.27518 (rank : 190)	NC score	0.006630 (rank : 882)
Query Neighborhood Hits	207	Target Neighborhood Hits	651	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

ABI2_MOUSE
θ value	6.88961 (rank : 191)	NC score	0.002227 (rank : 885)
Query Neighborhood Hits	207	Target Neighborhood Hits	266	Shared Neighborhood Hits	3
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

COFA1_HUMAN
θ value	6.88961 (rank : 192)	NC score	0.031047 (rank : 866)
Query Neighborhood Hits	207	Target Neighborhood Hits	292	Shared Neighborhood Hits	19
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

FOXC1_MOUSE
θ value	6.88961 (rank : 193)	NC score	-0.000717 (rank : 887)
Query Neighborhood Hits	207	Target Neighborhood Hits	218	Shared Neighborhood Hits	3
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

LRP1_HUMAN
θ value	6.88961 (rank : 194)	NC score	0.055574 (rank : 762)
Query Neighborhood Hits	207	Target Neighborhood Hits	617	Shared Neighborhood Hits	40
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

MCM3A_HUMAN
θ value	6.88961 (rank : 195)	NC score	0.008572 (rank : 879)
Query Neighborhood Hits	207	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	O60318, Q9UMT4	Gene names	MCM3AP, GANP, KIAA0572, MAP80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

TR19L_MOUSE
θ value	6.88961 (rank : 196)	NC score	0.023807 (rank : 867)
Query Neighborhood Hits	207	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

BCDO2_MOUSE
θ value	8.99809 (rank : 197)	NC score	0.010438 (rank : 876)
Query Neighborhood Hits	207	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q99NF1	Gene names	Bcdo2
Domain Architecture
Description	Beta,beta-carotene 9',10'-dioxygenase (EC 1.14.99.-) (Beta-carotene dioxygenase 2) (B-diox-II).

CRLF2_MOUSE
θ value	8.99809 (rank : 198)	NC score	0.075690 (rank : 582)
Query Neighborhood Hits	207	Target Neighborhood Hits	39	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CII9, Q9CRJ6, Q9JIE7, Q9JIQ7, Q9JJH8, Q9JMD5	Gene names	Crlf2, Crlm2, Tpte2, Tslpr
Domain Architecture
Description	Cytokine receptor-like factor 2 precursor (Type I cytokine receptor delta 1) (Cytokine receptor-like molecule 2) (CRLM-2) (Thymic stromal lymphopoietin protein receptor) (TSLPR).

CSF3R_MOUSE
θ value	8.99809 (rank : 199)	NC score	0.254560 (rank : 197)
Query Neighborhood Hits	207	Target Neighborhood Hits	104	Shared Neighborhood Hits	72
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

I10R2_MOUSE
θ value	8.99809 (rank : 200)	NC score	0.032700 (rank : 865)
Query Neighborhood Hits	207	Target Neighborhood Hits	52	Shared Neighborhood Hits	13
SwissProt Accessions	Q61190	Gene names	Il10rb, Crfb4
Domain Architecture
Description	Interleukin-10 receptor beta chain precursor (IL-10R-B) (IL-10R2) (Cytokine receptor family 2 member 4) (Cytokine receptor class-II member 4) (CRF2-4) (CDw210b antigen).

I11RB_MOUSE
θ value	8.99809 (rank : 201)	NC score	0.106731 (rank : 418)
Query Neighborhood Hits	207	Target Neighborhood Hits	101	Shared Neighborhood Hits	40
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

I13R1_HUMAN
θ value	8.99809 (rank : 202)	NC score	0.017495 (rank : 871)
Query Neighborhood Hits	207	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	P78552, O95646, Q99656	Gene names	IL13RA1, IL13R, IL13RA
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (CD213a1 antigen).

MYCD_MOUSE
θ value	8.99809 (rank : 203)	NC score	0.003953 (rank : 883)
Query Neighborhood Hits	207	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

NBR1_MOUSE
θ value	8.99809 (rank : 204)	NC score	0.010997 (rank : 875)
Query Neighborhood Hits	207	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

NRG2_HUMAN
θ value	8.99809 (rank : 205)	NC score	0.259295 (rank : 191)
Query Neighborhood Hits	207	Target Neighborhood Hits	419	Shared Neighborhood Hits	83
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG2_MOUSE
θ value	8.99809 (rank : 206)	NC score	0.257615 (rank : 193)
Query Neighborhood Hits	207	Target Neighborhood Hits	392	Shared Neighborhood Hits	81
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

TRI42_MOUSE
θ value	8.99809 (rank : 207)	NC score	0.069084 (rank : 631)
Query Neighborhood Hits	207	Target Neighborhood Hits	316	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

AATK_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.089708 (rank : 508)
Query Neighborhood Hits	207	Target Neighborhood Hits	1243	Shared Neighborhood Hits	59
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

AATK_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.092438 (rank : 482)
Query Neighborhood Hits	207	Target Neighborhood Hits	942	Shared Neighborhood Hits	51
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

ABL1_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.089126 (rank : 515)
Query Neighborhood Hits	207	Target Neighborhood Hits	1220	Shared Neighborhood Hits	52
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL1_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.089951 (rank : 504)
Query Neighborhood Hits	207	Target Neighborhood Hits	1178	Shared Neighborhood Hits	54
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ABL2_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.088837 (rank : 517)
Query Neighborhood Hits	207	Target Neighborhood Hits	1045	Shared Neighborhood Hits	50
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ACK1_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.097123 (rank : 456)
Query Neighborhood Hits	207	Target Neighborhood Hits	1140	Shared Neighborhood Hits	53
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

ACK1_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.098073 (rank : 452)
Query Neighborhood Hits	207	Target Neighborhood Hits	1080	Shared Neighborhood Hits	53
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ACV1B_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.055543 (rank : 763)
Query Neighborhood Hits	207	Target Neighborhood Hits	753	Shared Neighborhood Hits	48
SwissProt Accessions	P36896, Q15479, Q15480, Q15481, Q15482	Gene names	ACVR1B, ACVRLK4
Domain Architecture
Description	Activin receptor type 1B precursor (EC 2.7.11.30) (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2) (Activin receptor-like kinase 4) (ALK-4).

ACV1B_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.055912 (rank : 757)
Query Neighborhood Hits	207	Target Neighborhood Hits	753	Shared Neighborhood Hits	48
SwissProt Accessions	Q61271	Gene names	Acvr1b
Domain Architecture
Description	Activin receptor type 1B precursor (EC 2.7.11.30) (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2).

ACV1C_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.057071 (rank : 739)
Query Neighborhood Hits	207	Target Neighborhood Hits	709	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NER5, Q4ZFZ8, Q86UL1, Q86UL2, Q8TBG2	Gene names	ACVR1C, ALK7
Domain Architecture	No domain graphic available
Description	Activin receptor type 1C precursor (EC 2.7.11.30) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7).

ACV1C_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.054905 (rank : 771)
Query Neighborhood Hits	207	Target Neighborhood Hits	715	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K348	Gene names	Acvr1c, Alk7
Domain Architecture	No domain graphic available
Description	Activin receptor type 1C precursor (EC 2.7.11.30) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7).

ACVL1_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.058626 (rank : 726)
Query Neighborhood Hits	207	Target Neighborhood Hits	716	Shared Neighborhood Hits	44
SwissProt Accessions	P37023	Gene names	ACVRL1, ACVRLK1, ALK1
Domain Architecture
Description	Serine/threonine-protein kinase receptor R3 precursor (EC 2.7.11.30) (SKR3) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I).

ACVL1_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.061421 (rank : 695)
Query Neighborhood Hits	207	Target Neighborhood Hits	739	Shared Neighborhood Hits	45
SwissProt Accessions	Q61288, Q61289	Gene names	Acvrl1, Acvrlk1, Alk-1
Domain Architecture
Description	Serine/threonine-protein kinase receptor R3 precursor (EC 2.7.11.30) (SKR3) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I).

ACVR1_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.051037 (rank : 834)
Query Neighborhood Hits	207	Target Neighborhood Hits	760	Shared Neighborhood Hits	49
SwissProt Accessions	Q04771	Gene names	ACVR1, ACVRLK2
Domain Architecture
Description	Activin receptor type-1 precursor (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (Activin receptor-like kinase 2) (ALK-2) (TGF-B superfamily receptor type I) (TSR-I).

ACVR1_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.051690 (rank : 825)
Query Neighborhood Hits	207	Target Neighborhood Hits	768	Shared Neighborhood Hits	48
SwissProt Accessions	P37172, Q3UDH5, Q91VF1	Gene names	Acvr1, Acvrlk2, Tgfb1
Domain Architecture
Description	Activin receptor type-1 precursor (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I) (TSK-7L).

ALK_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.107152 (rank : 417)
Query Neighborhood Hits	207	Target Neighborhood Hits	795	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ALK_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.107984 (rank : 413)
Query Neighborhood Hits	207	Target Neighborhood Hits	811	Shared Neighborhood Hits	56
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

ANGL1_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.065851 (rank : 653)
Query Neighborhood Hits	207	Target Neighborhood Hits	86	Shared Neighborhood Hits	7
SwissProt Accessions	O95841, Q5T5Z5	Gene names	ANGPTL1, ANG3, ANGPT3, ARP1
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 1 precursor (Angiopoietin-like 1) (Angiopoietin-3) (ANG-3).

ANGL1_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.066220 (rank : 648)
Query Neighborhood Hits	207	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	Q640P2, Q3UQL1, Q9CZ81	Gene names	Angptl1
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 1 precursor (Angiopoietin-like 1).

ANGL2_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.066681 (rank : 644)
Query Neighborhood Hits	207	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKU9, Q5JT58	Gene names	ANGPTL2, ARP2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

ANGL2_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.066634 (rank : 645)
Query Neighborhood Hits	207	Target Neighborhood Hits	108	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R045	Gene names	Angptl2, Arp2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

ANGL3_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.058751 (rank : 725)
Query Neighborhood Hits	207	Target Neighborhood Hits	289	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5C1	Gene names	ANGPTL3, ANGPT5
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3) (Angiopoietin-5) (ANG-5).

ANGL3_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.063209 (rank : 673)
Query Neighborhood Hits	207	Target Neighborhood Hits	306	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

ANGL4_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.064132 (rank : 664)
Query Neighborhood Hits	207	Target Neighborhood Hits	79	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BY76, Q53HQ6, Q53HU1, Q6UXN0, Q9HBV4, Q9NZU4, Q9Y5B3	Gene names	ANGPTL4, ARP4, HFARP, PGAR
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP).

ANGL4_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.064674 (rank : 659)
Query Neighborhood Hits	207	Target Neighborhood Hits	64	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z1P8, Q78ZJ9, Q9JHX7, Q9JLX7	Gene names	Angptl4, Farp, Fiaf, Ng27
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP) (Fasting- induced adipose factor) (Secreted protein Bk89) (425O18-1).

ANGL5_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.069972 (rank : 625)
Query Neighborhood Hits	207	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	Q86XS5, Q86VR9	Gene names	ANGPTL5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 5 precursor (Angiopoietin-like 5).

ANGL6_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.070378 (rank : 622)
Query Neighborhood Hits	207	Target Neighborhood Hits	70	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NI99, Q9BZZ0	Gene names	ANGPTL6, AGF, ARP5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor) (Angiopoietin-related protein 5).

ANGL6_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.071610 (rank : 614)
Query Neighborhood Hits	207	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R0Z6	Gene names	Angptl6, Agf
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor).

ANGL7_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.071450 (rank : 615)
Query Neighborhood Hits	207	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	O43827, Q4ZGK4	Gene names	ANGPTL7, CDT6
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7) (Angiopoietin-like factor) (Cornea-derived transcript 6 protein).

ANGL7_MOUSE
θ value	θ > 10 (rank : 237)	NC score	0.071810 (rank : 613)
Query Neighborhood Hits	207	Target Neighborhood Hits	81	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R1Q3	Gene names	Angptl7
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7).

ANGP1_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.062373 (rank : 684)
Query Neighborhood Hits	207	Target Neighborhood Hits	254	Shared Neighborhood Hits	7
SwissProt Accessions	Q15389	Gene names	ANGPT1, KIAA0003
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

ANGP1_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.062280 (rank : 685)
Query Neighborhood Hits	207	Target Neighborhood Hits	252	Shared Neighborhood Hits	7
SwissProt Accessions	O08538	Gene names	Angpt1, Agpt
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

ANGP2_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.058939 (rank : 724)
Query Neighborhood Hits	207	Target Neighborhood Hits	400	Shared Neighborhood Hits	7
SwissProt Accessions	O15123, Q9NRR7, Q9P2Y7	Gene names	ANGPT2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

ANGP2_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.058295 (rank : 728)
Query Neighborhood Hits	207	Target Neighborhood Hits	397	Shared Neighborhood Hits	7
SwissProt Accessions	O35608, Q3U1A1, Q9D2D2	Gene names	Angpt2, Agpt2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

ANGP4_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.065472 (rank : 655)
Query Neighborhood Hits	207	Target Neighborhood Hits	187	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y264, Q9H4Z4	Gene names	ANGPT4, ANG3, ANG4
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

ANGP4_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.063671 (rank : 670)
Query Neighborhood Hits	207	Target Neighborhood Hits	220	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVH6	Gene names	Angpt4, Agpt4, Ang3
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

ANKK1_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.050780 (rank : 839)
Query Neighborhood Hits	207	Target Neighborhood Hits	1072	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

ANPRA_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.065260 (rank : 657)
Query Neighborhood Hits	207	Target Neighborhood Hits	612	Shared Neighborhood Hits	45
SwissProt Accessions	P16066, Q6P4Q3	Gene names	NPR1, ANPRA
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

ANPRA_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.068456 (rank : 637)
Query Neighborhood Hits	207	Target Neighborhood Hits	600	Shared Neighborhood Hits	45
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

ANPRB_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.060070 (rank : 711)
Query Neighborhood Hits	207	Target Neighborhood Hits	646	Shared Neighborhood Hits	44
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ANPRB_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.059640 (rank : 714)
Query Neighborhood Hits	207	Target Neighborhood Hits	607	Shared Neighborhood Hits	44
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ARAF_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.077396 (rank : 576)
Query Neighborhood Hits	207	Target Neighborhood Hits	924	Shared Neighborhood Hits	50
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

ARAF_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.077763 (rank : 571)
Query Neighborhood Hits	207	Target Neighborhood Hits	874	Shared Neighborhood Hits	50
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

ATL3_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.217289 (rank : 241)
Query Neighborhood Hits	207	Target Neighborhood Hits	414	Shared Neighborhood Hits	80
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

ATRN_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.057689 (rank : 736)
Query Neighborhood Hits	207	Target Neighborhood Hits	525	Shared Neighborhood Hits	27
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	θ > 10 (rank : 253)	NC score	0.054538 (rank : 778)
Query Neighborhood Hits	207	Target Neighborhood Hits	519	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

AURKC_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.050618 (rank : 844)
Query Neighborhood Hits	207	Target Neighborhood Hits	847	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UQB9, O60681, O75442, Q9UPK5	Gene names	AURKC, AIE2, AIK3, STK13
Domain Architecture
Description	Serine/threonine-protein kinase 13 (EC 2.7.11.1) (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C).

BASI_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.296223 (rank : 155)
Query Neighborhood Hits	207	Target Neighborhood Hits	211	Shared Neighborhood Hits	67
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

BASI_MOUSE
θ value	θ > 10 (rank : 256)	NC score	0.285994 (rank : 166)
Query Neighborhood Hits	207	Target Neighborhood Hits	238	Shared Neighborhood Hits	68
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

BLK_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.089501 (rank : 512)
Query Neighborhood Hits	207	Target Neighborhood Hits	994	Shared Neighborhood Hits	51
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BLK_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.090488 (rank : 499)
Query Neighborhood Hits	207	Target Neighborhood Hits	992	Shared Neighborhood Hits	51
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

BMPR2_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.056803 (rank : 744)
Query Neighborhood Hits	207	Target Neighborhood Hits	736	Shared Neighborhood Hits	46
SwissProt Accessions	Q13873, Q16569	Gene names	BMPR2, PPH1
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II).

BMPR2_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.055741 (rank : 759)
Query Neighborhood Hits	207	Target Neighborhood Hits	738	Shared Neighborhood Hits	46
SwissProt Accessions	O35607	Gene names	Bmpr2
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3).

BMR1A_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.053187 (rank : 793)
Query Neighborhood Hits	207	Target Neighborhood Hits	759	Shared Neighborhood Hits	48
SwissProt Accessions	P36894, Q8NEN8	Gene names	BMPR1A, ACVRLK3, ALK3
Domain Architecture
Description	Bone morphogenetic protein receptor type IA precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (CD292 antigen).

BMR1A_MOUSE
θ value	θ > 10 (rank : 262)	NC score	0.053173 (rank : 794)
Query Neighborhood Hits	207	Target Neighborhood Hits	758	Shared Neighborhood Hits	48
SwissProt Accessions	P36895	Gene names	Bmpr1a, Acvrlk3, Bmpr
Domain Architecture
Description	Bone morphogenetic protein receptor type IA precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (BMP-2/BMP-4 receptor).

BMR1B_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.050836 (rank : 838)
Query Neighborhood Hits	207	Target Neighborhood Hits	760	Shared Neighborhood Hits	46
SwissProt Accessions	O00238, P78366	Gene names	BMPR1B
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (CDw293 antigen).

BMR1B_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.051189 (rank : 831)
Query Neighborhood Hits	207	Target Neighborhood Hits	758	Shared Neighborhood Hits	46
SwissProt Accessions	P36898, Q3TRF2	Gene names	Bmpr1b, Acvrlk6
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R6) (SKR6) (Activin receptor-like kinase 6) (ALK-6).

BMX_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.090116 (rank : 502)
Query Neighborhood Hits	207	Target Neighborhood Hits	942	Shared Neighborhood Hits	50
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

BMX_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.090796 (rank : 493)
Query Neighborhood Hits	207	Target Neighborhood Hits	912	Shared Neighborhood Hits	50
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

BRAF1_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.077117 (rank : 579)
Query Neighborhood Hits	207	Target Neighborhood Hits	883	Shared Neighborhood Hits	50
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

BT3A2_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.055782 (rank : 758)
Query Neighborhood Hits	207	Target Neighborhood Hits	158	Shared Neighborhood Hits	30
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

BTK_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.090724 (rank : 496)
Query Neighborhood Hits	207	Target Neighborhood Hits	1026	Shared Neighborhood Hits	52
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

BTK_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.090670 (rank : 497)
Query Neighborhood Hits	207	Target Neighborhood Hits	1017	Shared Neighborhood Hits	52
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

BTNL2_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.061224 (rank : 697)
Query Neighborhood Hits	207	Target Neighborhood Hits	164	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

CD166_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.195160 (rank : 269)
Query Neighborhood Hits	207	Target Neighborhood Hits	247	Shared Neighborhood Hits	64
SwissProt Accessions	Q13740, O60892	Gene names	ALCAM, MEMD
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM).

CD166_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.214453 (rank : 245)
Query Neighborhood Hits	207	Target Neighborhood Hits	252	Shared Neighborhood Hits	67
SwissProt Accessions	Q61490, O70136, Q8CDA5, Q8R2T0	Gene names	Alcam
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM) (DM-GRASP protein).

CD22_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.286182 (rank : 165)
Query Neighborhood Hits	207	Target Neighborhood Hits	365	Shared Neighborhood Hits	76
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

CD22_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.297617 (rank : 154)
Query Neighborhood Hits	207	Target Neighborhood Hits	331	Shared Neighborhood Hits	72
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

CD276_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.151795 (rank : 339)
Query Neighborhood Hits	207	Target Neighborhood Hits	261	Shared Neighborhood Hits	43
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

CD276_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.100945 (rank : 434)
Query Neighborhood Hits	207	Target Neighborhood Hits	243	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

CD45_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.175447 (rank : 289)
Query Neighborhood Hits	207	Target Neighborhood Hits	178	Shared Neighborhood Hits	46
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

CD4_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.066040 (rank : 650)
Query Neighborhood Hits	207	Target Neighborhood Hits	122	Shared Neighborhood Hits	21
SwissProt Accessions	P01730, Q4ZGK2, Q5U066	Gene names	CD4
Domain Architecture
Description	T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3).

CD79A_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.104691 (rank : 423)
Query Neighborhood Hits	207	Target Neighborhood Hits	102	Shared Neighborhood Hits	36
SwissProt Accessions	P11912	Gene names	CD79A, IGA, MB1
Domain Architecture
Description	B-cell antigen receptor complex-associated protein alpha-chain precursor (Ig-alpha) (MB-1 membrane glycoprotein) (Surface IgM- associated protein) (Membrane-bound immunoglobulin-associated protein) (CD79a antigen).

CD80_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.078887 (rank : 565)
Query Neighborhood Hits	207	Target Neighborhood Hits	129	Shared Neighborhood Hits	37
SwissProt Accessions	P33681	Gene names	CD80, CD28LG, CD28LG1, LAB7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (CTLA-4 counter-receptor B7.1) (B7) (BB1).

CD80_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.064221 (rank : 662)
Query Neighborhood Hits	207	Target Neighborhood Hits	136	Shared Neighborhood Hits	27
SwissProt Accessions	Q00609, Q61332	Gene names	Cd80, B7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (B7).

CEA20_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.270127 (rank : 178)
Query Neighborhood Hits	207	Target Neighborhood Hits	251	Shared Neighborhood Hits	69
SwissProt Accessions	Q6UY09	Gene names	CEACAM20
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 20 precursor.

CEAM1_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.229473 (rank : 227)
Query Neighborhood Hits	207	Target Neighborhood Hits	348	Shared Neighborhood Hits	73
SwissProt Accessions	P13688, O60430, Q13858, Q15600, Q9UQV9	Gene names	CEACAM1, BGP, BGP1
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (CD66 antigen) (CD66a antigen).

CEAM1_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.263563 (rank : 186)
Query Neighborhood Hits	207	Target Neighborhood Hits	326	Shared Neighborhood Hits	73
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

CEAM5_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.276803 (rank : 169)
Query Neighborhood Hits	207	Target Neighborhood Hits	343	Shared Neighborhood Hits	77
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

CEAM6_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.195543 (rank : 267)
Query Neighborhood Hits	207	Target Neighborhood Hits	308	Shared Neighborhood Hits	75
SwissProt Accessions	P40199, Q14920	Gene names	CEACAM6, NCA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 6 precursor (Normal cross-reacting antigen) (Nonspecific crossreacting antigen) (CD66c antigen).

CEAM7_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.103690 (rank : 425)
Query Neighborhood Hits	207	Target Neighborhood Hits	170	Shared Neighborhood Hits	54
SwissProt Accessions	Q14002, O15148, O15149, Q13983, Q9UPJ2	Gene names	CEACAM7, CGM2
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 7 precursor (Carcinoembryonic antigen CGM2).

CEAM8_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.167067 (rank : 306)
Query Neighborhood Hits	207	Target Neighborhood Hits	264	Shared Neighborhood Hits	72
SwissProt Accessions	P31997, O60399, Q16574	Gene names	CEACAM8, CGM6
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 8 precursor (Carcinoembryonic antigen CGM6) (Nonspecific cross-reacting antigen NCA-95) (CD67 antigen) (CD66b antigen).

CI094_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.294086 (rank : 159)
Query Neighborhood Hits	207	Target Neighborhood Hits	310	Shared Neighborhood Hits	73
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

CILP1_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.153083 (rank : 332)
Query Neighborhood Hits	207	Target Neighborhood Hits	266	Shared Neighborhood Hits	75
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP1_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.150149 (rank : 347)
Query Neighborhood Hits	207	Target Neighborhood Hits	282	Shared Neighborhood Hits	71
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

CILP2_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.197628 (rank : 263)
Query Neighborhood Hits	207	Target Neighborhood Hits	307	Shared Neighborhood Hits	74
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

COCH_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.056964 (rank : 743)
Query Neighborhood Hits	207	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	O43405	Gene names	COCH, COCH5B2
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

COCH_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.056348 (rank : 749)
Query Neighborhood Hits	207	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q62507, Q3TAF5, Q9QWK6	Gene names	Coch
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

CRLF1_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.181439 (rank : 279)
Query Neighborhood Hits	207	Target Neighborhood Hits	122	Shared Neighborhood Hits	78
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

CRLF1_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.178662 (rank : 282)
Query Neighborhood Hits	207	Target Neighborhood Hits	116	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

CSF1R_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.140805 (rank : 359)
Query Neighborhood Hits	207	Target Neighborhood Hits	943	Shared Neighborhood Hits	101
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

CSF1R_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.174349 (rank : 293)
Query Neighborhood Hits	207	Target Neighborhood Hits	983	Shared Neighborhood Hits	109
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

CSK_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.088080 (rank : 523)
Query Neighborhood Hits	207	Target Neighborhood Hits	1009	Shared Neighborhood Hits	51
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

CSK_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.086664 (rank : 529)
Query Neighborhood Hits	207	Target Neighborhood Hits	1009	Shared Neighborhood Hits	51
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

CXAR_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.159286 (rank : 319)
Query Neighborhood Hits	207	Target Neighborhood Hits	245	Shared Neighborhood Hits	54
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

CXAR_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.146989 (rank : 352)
Query Neighborhood Hits	207	Target Neighborhood Hits	250	Shared Neighborhood Hits	54
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

DAPK2_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.055256 (rank : 767)
Query Neighborhood Hits	207	Target Neighborhood Hits	832	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UIK4, O75892	Gene names	DAPK2
Domain Architecture
Description	Death-associated protein kinase 2 (EC 2.7.11.1) (DAP kinase 2) (DAP- kinase-related protein 1) (DRP-1).

DAPK2_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.055627 (rank : 760)
Query Neighborhood Hits	207	Target Neighborhood Hits	834	Shared Neighborhood Hits	51
SwissProt Accessions	Q8VDF3, O88861, Q9QYM4	Gene names	Dapk2
Domain Architecture
Description	Death-associated protein kinase 2 (EC 2.7.11.1) (DAP kinase 2) (DAP- kinase-related protein 1) (DRP-1).

DAPK3_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.055273 (rank : 766)
Query Neighborhood Hits	207	Target Neighborhood Hits	945	Shared Neighborhood Hits	50
SwissProt Accessions	O43293	Gene names	DAPK3, ZIPK
Domain Architecture
Description	Death-associated protein kinase 3 (EC 2.7.11.1) (DAP kinase 3) (DAP- like kinase) (Dlk) (ZIP-kinase).

DAPK3_MOUSE
θ value	θ > 10 (rank : 307)	NC score	0.054893 (rank : 772)
Query Neighborhood Hits	207	Target Neighborhood Hits	843	Shared Neighborhood Hits	50
SwissProt Accessions	O54784	Gene names	Dapk3, Zipk
Domain Architecture
Description	Death-associated protein kinase 3 (EC 2.7.11.1) (DAP kinase 3) (DAP- like kinase) (Dlk) (ZIP-kinase).

DDR1_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.102434 (rank : 428)
Query Neighborhood Hits	207	Target Neighborhood Hits	819	Shared Neighborhood Hits	50
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

DDR1_MOUSE
θ value	θ > 10 (rank : 309)	NC score	0.101629 (rank : 430)
Query Neighborhood Hits	207	Target Neighborhood Hits	818	Shared Neighborhood Hits	50
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

DDR2_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.101254 (rank : 432)
Query Neighborhood Hits	207	Target Neighborhood Hits	818	Shared Neighborhood Hits	50
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DDR2_MOUSE
θ value	θ > 10 (rank : 311)	NC score	0.100270 (rank : 438)
Query Neighborhood Hits	207	Target Neighborhood Hits	813	Shared Neighborhood Hits	50
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

DLK_HUMAN
θ value	θ > 10 (rank : 312)	NC score	0.053135 (rank : 795)
Query Neighborhood Hits	207	Target Neighborhood Hits	401	Shared Neighborhood Hits	23
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	θ > 10 (rank : 313)	NC score	0.051252 (rank : 828)
Query Neighborhood Hits	207	Target Neighborhood Hits	374	Shared Neighborhood Hits	19
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL4_HUMAN
θ value	θ > 10 (rank : 314)	NC score	0.050694 (rank : 842)
Query Neighborhood Hits	207	Target Neighborhood Hits	435	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
θ value	θ > 10 (rank : 315)	NC score	0.053062 (rank : 796)
Query Neighborhood Hits	207	Target Neighborhood Hits	440	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

EGFL9_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.052656 (rank : 803)
Query Neighborhood Hits	207	Target Neighborhood Hits	365	Shared Neighborhood Hits	23
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 317)	NC score	0.052435 (rank : 805)
Query Neighborhood Hits	207	Target Neighborhood Hits	379	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

EGFR_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.096673 (rank : 460)
Query Neighborhood Hits	207	Target Neighborhood Hits	939	Shared Neighborhood Hits	52
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

EGFR_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.097463 (rank : 454)
Query Neighborhood Hits	207	Target Neighborhood Hits	927	Shared Neighborhood Hits	54
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

EMB_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.074567 (rank : 587)
Query Neighborhood Hits	207	Target Neighborhood Hits	54	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PCB8	Gene names	EMB
Domain Architecture	No domain graphic available
Description	Embigin precursor.

EMB_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.164600 (rank : 310)
Query Neighborhood Hits	207	Target Neighborhood Hits	83	Shared Neighborhood Hits	39
SwissProt Accessions	P21995, Q3UFF1, Q8C2J8, Q8C543, Q96C38	Gene names	Emb, Gp70
Domain Architecture
Description	Embigin precursor (Teratocarcinoma glycoprotein Gp-70).

ERBB2_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.097852 (rank : 453)
Query Neighborhood Hits	207	Target Neighborhood Hits	1073	Shared Neighborhood Hits	56
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

ERBB2_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.097024 (rank : 458)
Query Neighborhood Hits	207	Target Neighborhood Hits	918	Shared Neighborhood Hits	51
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

ERBB3_HUMAN
θ value	θ > 10 (rank : 324)	NC score	0.096486 (rank : 461)
Query Neighborhood Hits	207	Target Neighborhood Hits	918	Shared Neighborhood Hits	52
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

ERBB3_MOUSE
θ value	θ > 10 (rank : 325)	NC score	0.094503 (rank : 472)
Query Neighborhood Hits	207	Target Neighborhood Hits	898	Shared Neighborhood Hits	51
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

ERBB4_HUMAN
θ value	θ > 10 (rank : 326)	NC score	0.098919 (rank : 445)
Query Neighborhood Hits	207	Target Neighborhood Hits	910	Shared Neighborhood Hits	54
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

ESAM_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.159805 (rank : 318)
Query Neighborhood Hits	207	Target Neighborhood Hits	251	Shared Neighborhood Hits	57
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

ESAM_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.146887 (rank : 353)
Query Neighborhood Hits	207	Target Neighborhood Hits	222	Shared Neighborhood Hits	57
SwissProt Accessions	Q925F2	Gene names	Esam, Esam1
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

FAK1_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.100209 (rank : 439)
Query Neighborhood Hits	207	Target Neighborhood Hits	850	Shared Neighborhood Hits	50
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

FAK1_MOUSE
θ value	θ > 10 (rank : 330)	NC score	0.099895 (rank : 440)
Query Neighborhood Hits	207	Target Neighborhood Hits	850	Shared Neighborhood Hits	50
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

FAK2_HUMAN
θ value	θ > 10 (rank : 331)	NC score	0.100327 (rank : 437)
Query Neighborhood Hits	207	Target Neighborhood Hits	847	Shared Neighborhood Hits	50
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FAK2_MOUSE
θ value	θ > 10 (rank : 332)	NC score	0.099756 (rank : 442)
Query Neighborhood Hits	207	Target Neighborhood Hits	851	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

FCERA_HUMAN
θ value	θ > 10 (rank : 333)	NC score	0.098090 (rank : 451)
Query Neighborhood Hits	207	Target Neighborhood Hits	150	Shared Neighborhood Hits	39
SwissProt Accessions	P12319	Gene names	FCER1A, FCE1A
Domain Architecture
Description	High affinity immunoglobulin epsilon receptor alpha-subunit precursor (FcERI) (IgE Fc receptor, alpha-subunit) (Fc-epsilon RI-alpha).

FCGR1_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.092876 (rank : 479)
Query Neighborhood Hits	207	Target Neighborhood Hits	145	Shared Neighborhood Hits	42
SwissProt Accessions	P12314, P12315, Q92495, Q92663	Gene names	FCGR1A, FCG1, FCGR1, IGFR1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I) (CD64 antigen).

FCGR1_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.071957 (rank : 611)
Query Neighborhood Hits	207	Target Neighborhood Hits	123	Shared Neighborhood Hits	35
SwissProt Accessions	P26151	Gene names	Fcgr1, Fcg1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I).

FCN1_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.085533 (rank : 534)
Query Neighborhood Hits	207	Target Neighborhood Hits	147	Shared Neighborhood Hits	15
SwissProt Accessions	O00602, Q92596	Gene names	FCN1
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

FCN1_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.086852 (rank : 526)
Query Neighborhood Hits	207	Target Neighborhood Hits	173	Shared Neighborhood Hits	15
SwissProt Accessions	O70165	Gene names	Fcn1, Fcna
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

FCN2_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.083678 (rank : 539)
Query Neighborhood Hits	207	Target Neighborhood Hits	122	Shared Neighborhood Hits	14
SwissProt Accessions	Q15485, Q9UC57	Gene names	FCN2
Domain Architecture
Description	Ficolin-2 precursor (Collagen/fibrinogen domain-containing protein 2) (Ficolin-B) (Ficolin B) (Serum lectin p35) (EBP-37) (Hucolin) (L- Ficolin).

FCN3_HUMAN
θ value	θ > 10 (rank : 339)	NC score	0.083514 (rank : 542)
Query Neighborhood Hits	207	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	O75636, Q6IBJ5, Q8WW86	Gene names	FCN3, HAKA1
Domain Architecture
Description	Ficolin-3 precursor (Collagen/fibrinogen domain-containing protein 3) (Collagen/fibrinogen domain-containing lectin 3 p35) (Hakata antigen).

FCRL2_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.265458 (rank : 184)
Query Neighborhood Hits	207	Target Neighborhood Hits	251	Shared Neighborhood Hits	69
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

FCRL5_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.272929 (rank : 175)
Query Neighborhood Hits	207	Target Neighborhood Hits	267	Shared Neighborhood Hits	64
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

FCRLA_HUMAN
θ value	θ > 10 (rank : 342)	NC score	0.072924 (rank : 597)
Query Neighborhood Hits	207	Target Neighborhood Hits	135	Shared Neighborhood Hits	21
SwissProt Accessions	Q7L513, Q5VXA1, Q5VXA2, Q5VXA3, Q5VXB0, Q8NEW4, Q8WXH3, Q96PC6, Q96PJ0, Q96PJ1, Q96PJ2, Q96PJ4, Q9BR57	Gene names	FCRLA, FCRL, FCRL1, FCRLM1, FCRX, FREB
Domain Architecture	No domain graphic available
Description	Fc receptor-like and mucin-like 1 precursor (Fc receptor-like A) (Fc receptor homolog expressed in B-cells) (Fc receptor-related protein X) (FcRX) (Fc receptor-like protein).

FCRLA_MOUSE
θ value	θ > 10 (rank : 343)	NC score	0.054772 (rank : 773)
Query Neighborhood Hits	207	Target Neighborhood Hits	110	Shared Neighborhood Hits	20
SwissProt Accessions	Q920A9, Q3T9Q2, Q8K3U9, Q8VHP5	Gene names	Fcrla, Fcrl, Fcrl1, Fcrlm1, Fcrx, Freb
Domain Architecture	No domain graphic available
Description	Fc receptor-like and mucin-like 1 precursor (Fc receptor-like A) (Fc receptor homolog expressed in B-cells) (Fc receptor-related protein X) (FcRX) (Fc receptor-like protein).

FER_HUMAN
θ value	θ > 10 (rank : 344)	NC score	0.092774 (rank : 481)
Query Neighborhood Hits	207	Target Neighborhood Hits	1278	Shared Neighborhood Hits	50
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

FES_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.094199 (rank : 474)
Query Neighborhood Hits	207	Target Neighborhood Hits	978	Shared Neighborhood Hits	50
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FES_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.094070 (rank : 475)
Query Neighborhood Hits	207	Target Neighborhood Hits	980	Shared Neighborhood Hits	50
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FGFR1_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.206154 (rank : 256)
Query Neighborhood Hits	207	Target Neighborhood Hits	1069	Shared Neighborhood Hits	116
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

FGFR1_MOUSE
θ value	θ > 10 (rank : 348)	NC score	0.206223 (rank : 255)
Query Neighborhood Hits	207	Target Neighborhood Hits	1068	Shared Neighborhood Hits	116
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

FGFR2_HUMAN
θ value	θ > 10 (rank : 349)	NC score	0.204549 (rank : 257)
Query Neighborhood Hits	207	Target Neighborhood Hits	1062	Shared Neighborhood Hits	116
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

FGFR2_MOUSE
θ value	θ > 10 (rank : 350)	NC score	0.197777 (rank : 262)
Query Neighborhood Hits	207	Target Neighborhood Hits	1062	Shared Neighborhood Hits	116
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

FGFR3_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.203488 (rank : 258)
Query Neighborhood Hits	207	Target Neighborhood Hits	1042	Shared Neighborhood Hits	116
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

FGFR3_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.208849 (rank : 252)
Query Neighborhood Hits	207	Target Neighborhood Hits	1059	Shared Neighborhood Hits	118
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

FGFR4_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.210202 (rank : 250)
Query Neighborhood Hits	207	Target Neighborhood Hits	1037	Shared Neighborhood Hits	117
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

FGFR4_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.213738 (rank : 247)
Query Neighborhood Hits	207	Target Neighborhood Hits	1026	Shared Neighborhood Hits	117
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

FGL1_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.071010 (rank : 620)
Query Neighborhood Hits	207	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	Q08830, Q4PJH9, Q96KW6, Q96QM6	Gene names	FGL1, HFREP1
Domain Architecture
Description	Fibrinogen-like protein 1 precursor (Hepatocyte-derived fibrinogen- related protein 1) (HFREP-1) (Hepassocin) (HP-041).

FGL2_HUMAN
θ value	θ > 10 (rank : 356)	NC score	0.068970 (rank : 634)
Query Neighborhood Hits	207	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	Q14314	Gene names	FGL2
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (pT49).

FGL2_MOUSE
θ value	θ > 10 (rank : 357)	NC score	0.070298 (rank : 623)
Query Neighborhood Hits	207	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	P12804	Gene names	Fgl2, Fiblp
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (Prothrombinase) (Cytotoxic T-lymphocyte-specific protein).

FGRL1_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.399904 (rank : 91)
Query Neighborhood Hits	207	Target Neighborhood Hits	335	Shared Neighborhood Hits	82
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

FGRL1_MOUSE
θ value	θ > 10 (rank : 359)	NC score	0.398365 (rank : 93)
Query Neighborhood Hits	207	Target Neighborhood Hits	325	Shared Neighborhood Hits	83
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

FGR_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.089823 (rank : 505)
Query Neighborhood Hits	207	Target Neighborhood Hits	1067	Shared Neighborhood Hits	52
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FGR_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.089350 (rank : 514)
Query Neighborhood Hits	207	Target Neighborhood Hits	1069	Shared Neighborhood Hits	52
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FIBA_HUMAN
θ value	θ > 10 (rank : 362)	NC score	0.068838 (rank : 636)
Query Neighborhood Hits	207	Target Neighborhood Hits	132	Shared Neighborhood Hits	9
SwissProt Accessions	P02671, Q9BX62, Q9UCH2	Gene names	FGA
Domain Architecture
Description	Fibrinogen alpha chain precursor [Contains: Fibrinopeptide A].

FIBB_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.067319 (rank : 642)
Query Neighborhood Hits	207	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	P02675	Gene names	FGB
Domain Architecture
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

FIBB_MOUSE
θ value	θ > 10 (rank : 364)	NC score	0.067582 (rank : 639)
Query Neighborhood Hits	207	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K0E8, Q91ZP1	Gene names	Fgb
Domain Architecture	No domain graphic available
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

FIBG_HUMAN
θ value	θ > 10 (rank : 365)	NC score	0.061578 (rank : 693)
Query Neighborhood Hits	207	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	P02679, P04469, P04470, Q96A14, Q96KJ3	Gene names	FGG
Domain Architecture
Description	Fibrinogen gamma chain precursor.

FIBG_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.061928 (rank : 689)
Query Neighborhood Hits	207	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VCM7, Q8WUR3, Q91ZP0	Gene names	Fgg
Domain Architecture	No domain graphic available
Description	Fibrinogen gamma chain precursor.

FLT3_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.106325 (rank : 419)
Query Neighborhood Hits	207	Target Neighborhood Hits	843	Shared Neighborhood Hits	67
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

FLT3_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.119360 (rank : 391)
Query Neighborhood Hits	207	Target Neighborhood Hits	847	Shared Neighborhood Hits	80
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

FPRP_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.058281 (rank : 729)
Query Neighborhood Hits	207	Target Neighborhood Hits	130	Shared Neighborhood Hits	33
SwissProt Accessions	Q9P2B2, Q8N2K6	Gene names	PTGFRN, CD9P1, FPRP, KIAA1436
Domain Architecture
Description	Prostaglandin F2 receptor negative regulator precursor (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD9 partner 1) (CD9P-1) (CD315 antigen).

FPRP_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.062429 (rank : 682)
Query Neighborhood Hits	207	Target Neighborhood Hits	116	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WV91	Gene names	Ptgfrn, Fprp
Domain Architecture
Description	Prostaglandin F2 receptor negative regulator precursor (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD315 antigen).

FRK_HUMAN
θ value	θ > 10 (rank : 371)	NC score	0.089638 (rank : 509)
Query Neighborhood Hits	207	Target Neighborhood Hits	1058	Shared Neighborhood Hits	51
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

FSTL4_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.314462 (rank : 136)
Query Neighborhood Hits	207	Target Neighborhood Hits	344	Shared Neighborhood Hits	80
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

FSTL4_MOUSE
θ value	θ > 10 (rank : 373)	NC score	0.314146 (rank : 138)
Query Neighborhood Hits	207	Target Neighborhood Hits	333	Shared Neighborhood Hits	77
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

FSTL5_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.320926 (rank : 131)
Query Neighborhood Hits	207	Target Neighborhood Hits	347	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

FSTL5_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.314807 (rank : 135)
Query Neighborhood Hits	207	Target Neighborhood Hits	355	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

FYN_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.086766 (rank : 528)
Query Neighborhood Hits	207	Target Neighborhood Hits	1078	Shared Neighborhood Hits	51
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

FYN_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.087271 (rank : 525)
Query Neighborhood Hits	207	Target Neighborhood Hits	1073	Shared Neighborhood Hits	51
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

GPA33_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.197234 (rank : 264)
Query Neighborhood Hits	207	Target Neighborhood Hits	273	Shared Neighborhood Hits	59
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

GPA33_MOUSE
θ value	θ > 10 (rank : 379)	NC score	0.203118 (rank : 259)
Query Neighborhood Hits	207	Target Neighborhood Hits	294	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

GUC2C_HUMAN
θ value	θ > 10 (rank : 380)	NC score	0.078246 (rank : 567)
Query Neighborhood Hits	207	Target Neighborhood Hits	624	Shared Neighborhood Hits	46
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

GUC2D_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.066534 (rank : 646)
Query Neighborhood Hits	207	Target Neighborhood Hits	715	Shared Neighborhood Hits	48
SwissProt Accessions	Q02846, Q6LEA7	Gene names	GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1
Domain Architecture
Description	Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2) (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC).

GUC2E_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.070850 (rank : 621)
Query Neighborhood Hits	207	Target Neighborhood Hits	692	Shared Neighborhood Hits	48
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

GUC2F_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.079301 (rank : 561)
Query Neighborhood Hits	207	Target Neighborhood Hits	740	Shared Neighborhood Hits	49
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

GUC2G_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.060516 (rank : 706)
Query Neighborhood Hits	207	Target Neighborhood Hits	644	Shared Neighborhood Hits	44
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

HCK_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.091009 (rank : 490)
Query Neighborhood Hits	207	Target Neighborhood Hits	1035	Shared Neighborhood Hits	52
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

HCK_MOUSE
θ value	θ > 10 (rank : 386)	NC score	0.091326 (rank : 489)
Query Neighborhood Hits	207	Target Neighborhood Hits	1029	Shared Neighborhood Hits	51
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

HHLA2_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.106038 (rank : 421)
Query Neighborhood Hits	207	Target Neighborhood Hits	140	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

HMCN1_HUMAN
θ value	θ > 10 (rank : 388)	NC score	0.311328 (rank : 144)
Query Neighborhood Hits	207	Target Neighborhood Hits	983	Shared Neighborhood Hits	107
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

I11RA_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.089461 (rank : 513)
Query Neighborhood Hits	207	Target Neighborhood Hits	138	Shared Neighborhood Hits	42
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

I11RA_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.094319 (rank : 473)
Query Neighborhood Hits	207	Target Neighborhood Hits	95	Shared Neighborhood Hits	35
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

I12R1_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.169854 (rank : 299)
Query Neighborhood Hits	207	Target Neighborhood Hits	78	Shared Neighborhood Hits	59
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

I12R1_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.158386 (rank : 322)
Query Neighborhood Hits	207	Target Neighborhood Hits	70	Shared Neighborhood Hits	51
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

I12R2_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.364014 (rank : 104)
Query Neighborhood Hits	207	Target Neighborhood Hits	163	Shared Neighborhood Hits	106
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

I27RA_HUMAN
θ value	θ > 10 (rank : 394)	NC score	0.137207 (rank : 366)
Query Neighborhood Hits	207	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q6UWB1, O60624	Gene names	IL27RA, CRL1, TCCR, WSX1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR) (Protein CRL1).

I27RA_MOUSE
θ value	θ > 10 (rank : 395)	NC score	0.083300 (rank : 543)
Query Neighborhood Hits	207	Target Neighborhood Hits	55	Shared Neighborhood Hits	30
SwissProt Accessions	O70394	Gene names	Il27ra, Tccr, Wsx1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR).

IBP7_HUMAN
θ value	θ > 10 (rank : 396)	NC score	0.268879 (rank : 181)
Query Neighborhood Hits	207	Target Neighborhood Hits	220	Shared Neighborhood Hits	69
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

IBP7_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.269025 (rank : 180)
Query Neighborhood Hits	207	Target Neighborhood Hits	230	Shared Neighborhood Hits	72
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

ICAM1_MOUSE
θ value	θ > 10 (rank : 398)	NC score	0.067493 (rank : 640)
Query Neighborhood Hits	207	Target Neighborhood Hits	99	Shared Neighborhood Hits	31
SwissProt Accessions	P13597, Q61828	Gene names	Icam1, Icam-1
Domain Architecture
Description	Intercellular adhesion molecule 1 precursor (ICAM-1) (MALA-2).

ICAM3_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.055247 (rank : 768)
Query Neighborhood Hits	207	Target Neighborhood Hits	100	Shared Neighborhood Hits	35
SwissProt Accessions	P32942	Gene names	ICAM3
Domain Architecture
Description	Intercellular adhesion molecule 3 precursor (ICAM-3) (ICAM-R) (CDw50) (CD50 antigen).

ICAM5_HUMAN
θ value	θ > 10 (rank : 400)	NC score	0.306385 (rank : 148)
Query Neighborhood Hits	207	Target Neighborhood Hits	276	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

ICAM5_MOUSE
θ value	θ > 10 (rank : 401)	NC score	0.312639 (rank : 140)
Query Neighborhood Hits	207	Target Neighborhood Hits	308	Shared Neighborhood Hits	73
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

IGS21_HUMAN
θ value	θ > 10 (rank : 402)	NC score	0.136876 (rank : 367)
Query Neighborhood Hits	207	Target Neighborhood Hits	123	Shared Neighborhood Hits	43
SwissProt Accessions	Q96ID5, Q8NBR8	Gene names	IGSF21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

IGS21_MOUSE
θ value	θ > 10 (rank : 403)	NC score	0.135164 (rank : 368)
Query Neighborhood Hits	207	Target Neighborhood Hits	118	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TNR6	Gene names	Igsf21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

IGS4B_HUMAN
θ value	θ > 10 (rank : 404)	NC score	0.248961 (rank : 202)
Query Neighborhood Hits	207	Target Neighborhood Hits	305	Shared Neighborhood Hits	73
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

IGS4B_MOUSE
θ value	θ > 10 (rank : 405)	NC score	0.252932 (rank : 199)
Query Neighborhood Hits	207	Target Neighborhood Hits	328	Shared Neighborhood Hits	72
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

IGSF2_HUMAN
θ value	θ > 10 (rank : 406)	NC score	0.063742 (rank : 668)
Query Neighborhood Hits	207	Target Neighborhood Hits	208	Shared Neighborhood Hits	32
SwissProt Accessions	Q93033, Q15856	Gene names	IGSF2, CD101, EWI101, V7
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 2 precursor (Glu-Trp-Ile EWI motif- containing protein 101) (EWI-101) (Cell surface glycoprotein V7) (CD101 antigen).

IKKA_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.060625 (rank : 703)
Query Neighborhood Hits	207	Target Neighborhood Hits	863	Shared Neighborhood Hits	50
SwissProt Accessions	O15111, O14666, Q13132, Q92467	Gene names	CHUK, IKKA
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase alpha subunit (EC 2.7.11.10) (I kappa-B kinase alpha) (IkBKA) (IKK-alpha) (IKK-A) (IkappaB kinase) (I-kappa-B kinase 1) (IKK1) (Conserved helix-loop- helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA).

IKKA_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.059783 (rank : 713)
Query Neighborhood Hits	207	Target Neighborhood Hits	867	Shared Neighborhood Hits	50
SwissProt Accessions	Q60680, Q80VU2, Q9D2X3	Gene names	Chuk, Ikka
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase alpha subunit (EC 2.7.11.10) (I kappa-B kinase alpha) (IkBKA) (IKK-alpha) (IKK-A) (IkappaB kinase) (I-kappa-B kinase 1) (IKK1) (Conserved helix-loop- helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA).

IKKB_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.057968 (rank : 734)
Query Neighborhood Hits	207	Target Neighborhood Hits	980	Shared Neighborhood Hits	50
SwissProt Accessions	O14920, O75327	Gene names	IKBKB, IKKB
Domain Architecture
Description	Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB).

IKKB_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.058008 (rank : 733)
Query Neighborhood Hits	207	Target Neighborhood Hits	984	Shared Neighborhood Hits	50
SwissProt Accessions	O88351, Q9R1J6	Gene names	Ikbkb, Ikkb
Domain Architecture
Description	Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB).

IKKE_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.051384 (rank : 827)
Query Neighborhood Hits	207	Target Neighborhood Hits	837	Shared Neighborhood Hits	47
SwissProt Accessions	Q14164	Gene names	IKBKE, IKKE, IKKI, KIAA0151
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).

IKKE_MOUSE
θ value	θ > 10 (rank : 412)	NC score	0.051907 (rank : 818)
Query Neighborhood Hits	207	Target Neighborhood Hits	848	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0T8	Gene names	Ikbke, Ikke, Ikki
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).

IL1R1_HUMAN
θ value	θ > 10 (rank : 413)	NC score	0.127236 (rank : 374)
Query Neighborhood Hits	207	Target Neighborhood Hits	140	Shared Neighborhood Hits	50
SwissProt Accessions	P14778	Gene names	IL1R1, IL1R, IL1RA, IL1RT1
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (IL-1RT1) (IL-1R- alpha) (p80) (CD121a antigen).

IL1R1_MOUSE
θ value	θ > 10 (rank : 414)	NC score	0.126015 (rank : 377)
Query Neighborhood Hits	207	Target Neighborhood Hits	142	Shared Neighborhood Hits	56
SwissProt Accessions	P13504	Gene names	Il1r1, Il-1r1, Il1ra
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (p80) (CD121a antigen).

IL1R2_HUMAN
θ value	θ > 10 (rank : 415)	NC score	0.199416 (rank : 260)
Query Neighborhood Hits	207	Target Neighborhood Hits	153	Shared Neighborhood Hits	54
SwissProt Accessions	P27930, Q9UE68	Gene names	IL1R2, IL1RB
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen) (CDw121b).

IL1R2_MOUSE
θ value	θ > 10 (rank : 416)	NC score	0.162580 (rank : 313)
Query Neighborhood Hits	207	Target Neighborhood Hits	125	Shared Neighborhood Hits	48
SwissProt Accessions	P27931	Gene names	Il1r2, Il-1r2, Il1rb
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen).

IL27B_HUMAN
θ value	θ > 10 (rank : 417)	NC score	0.178632 (rank : 283)
Query Neighborhood Hits	207	Target Neighborhood Hits	80	Shared Neighborhood Hits	57
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

IL27B_MOUSE
θ value	θ > 10 (rank : 418)	NC score	0.065883 (rank : 652)
Query Neighborhood Hits	207	Target Neighborhood Hits	55	Shared Neighborhood Hits	29
SwissProt Accessions	O35228	Gene names	Ebi3, Il17b
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein homolog).

IL6RA_HUMAN
θ value	θ > 10 (rank : 419)	NC score	0.056085 (rank : 752)
Query Neighborhood Hits	207	Target Neighborhood Hits	96	Shared Neighborhood Hits	30
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

IL6RA_MOUSE
θ value	θ > 10 (rank : 420)	NC score	0.075920 (rank : 581)
Query Neighborhood Hits	207	Target Neighborhood Hits	104	Shared Neighborhood Hits	38
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

ILK1_HUMAN
θ value	θ > 10 (rank : 421)	NC score	0.080680 (rank : 555)
Query Neighborhood Hits	207	Target Neighborhood Hits	857	Shared Neighborhood Hits	50
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

ILK2_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.080021 (rank : 558)
Query Neighborhood Hits	207	Target Neighborhood Hits	848	Shared Neighborhood Hits	50
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

ILK_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.080732 (rank : 554)
Query Neighborhood Hits	207	Target Neighborhood Hits	858	Shared Neighborhood Hits	50
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ILRL1_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.107433 (rank : 416)
Query Neighborhood Hits	207	Target Neighborhood Hits	167	Shared Neighborhood Hits	48
SwissProt Accessions	Q01638, Q53TU7, Q8NEJ3, Q9ULV7, Q9UQ44	Gene names	IL1RL1, DER4, ST2, T1
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein).

ILRL1_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.072850 (rank : 599)
Query Neighborhood Hits	207	Target Neighborhood Hits	172	Shared Neighborhood Hits	42
SwissProt Accessions	P14719, Q05208	Gene names	Il1rl1, Ly84, St2, Ste2
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein) (T1 protein) (Lymphocyte antigen 84).

ILRL2_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.084379 (rank : 537)
Query Neighborhood Hits	207	Target Neighborhood Hits	112	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HB29, Q13525, Q45H74	Gene names	IL1RL2, IL1RRP2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2) (Interleukin-1 receptor-related protein 2) (IL1R-rp2).

ILRL2_MOUSE
θ value	θ > 10 (rank : 427)	NC score	0.126815 (rank : 375)
Query Neighborhood Hits	207	Target Neighborhood Hits	158	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ERS7	Gene names	Il1rl2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2).

INAR1_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.051765 (rank : 822)
Query Neighborhood Hits	207	Target Neighborhood Hits	49	Shared Neighborhood Hits	17
SwissProt Accessions	P17181, Q53GW9, Q53H11, Q8WTZ2	Gene names	IFNAR1, IFNAR
Domain Architecture	No domain graphic available
Description	Interferon-alpha/beta receptor alpha chain precursor (IFN-alpha-REC).

IRAK1_HUMAN
θ value	θ > 10 (rank : 429)	NC score	0.062090 (rank : 688)
Query Neighborhood Hits	207	Target Neighborhood Hits	820	Shared Neighborhood Hits	49
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

IRAK1_MOUSE
θ value	θ > 10 (rank : 430)	NC score	0.061140 (rank : 699)
Query Neighborhood Hits	207	Target Neighborhood Hits	784	Shared Neighborhood Hits	49
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

IRAK2_HUMAN
θ value	θ > 10 (rank : 431)	NC score	0.059112 (rank : 719)
Query Neighborhood Hits	207	Target Neighborhood Hits	714	Shared Neighborhood Hits	48
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

IRAK3_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.080285 (rank : 557)
Query Neighborhood Hits	207	Target Neighborhood Hits	644	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

IRAK3_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.083111 (rank : 545)
Query Neighborhood Hits	207	Target Neighborhood Hits	628	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

IRAK4_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.066732 (rank : 643)
Query Neighborhood Hits	207	Target Neighborhood Hits	816	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NWZ3, Q8TDF7, Q9Y589	Gene names	IRAK4
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (IRAK-4) (NY- REN-64 antigen).

IRAK4_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.066017 (rank : 651)
Query Neighborhood Hits	207	Target Neighborhood Hits	820	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4K2, Q80WW1	Gene names	Irak4
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (IRAK-4).

IRPL1_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.152770 (rank : 335)
Query Neighborhood Hits	207	Target Neighborhood Hits	196	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NZN1, Q9UJ53	Gene names	IL1RAPL1, OPHN4
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2).

IRPL1_MOUSE
θ value	θ > 10 (rank : 437)	NC score	0.161512 (rank : 314)
Query Neighborhood Hits	207	Target Neighborhood Hits	186	Shared Neighborhood Hits	64
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

IRPL2_HUMAN
θ value	θ > 10 (rank : 438)	NC score	0.171514 (rank : 295)
Query Neighborhood Hits	207	Target Neighborhood Hits	194	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NP60, Q9NZN0	Gene names	IL1RAPL2, IL1R9
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R9) (IL-1 receptor accessory protein-like 2) (Three immunoglobulin domain- containing IL-1 receptor-related 1) (TIGIRR-1).

IRPL2_MOUSE
θ value	θ > 10 (rank : 439)	NC score	0.169874 (rank : 298)
Query Neighborhood Hits	207	Target Neighborhood Hits	195	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ERS6, Q9ER66	Gene names	Il1rapl2
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (TIGIRR-1).

ITB1_HUMAN
θ value	θ > 10 (rank : 440)	NC score	0.062145 (rank : 686)
Query Neighborhood Hits	207	Target Neighborhood Hits	298	Shared Neighborhood Hits	17
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB1_MOUSE
θ value	θ > 10 (rank : 441)	NC score	0.060921 (rank : 702)
Query Neighborhood Hits	207	Target Neighborhood Hits	283	Shared Neighborhood Hits	15
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB2_HUMAN
θ value	θ > 10 (rank : 442)	NC score	0.063139 (rank : 674)
Query Neighborhood Hits	207	Target Neighborhood Hits	282	Shared Neighborhood Hits	29
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB2_MOUSE
θ value	θ > 10 (rank : 443)	NC score	0.065411 (rank : 656)
Query Neighborhood Hits	207	Target Neighborhood Hits	326	Shared Neighborhood Hits	29
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB3_HUMAN
θ value	θ > 10 (rank : 444)	NC score	0.064188 (rank : 663)
Query Neighborhood Hits	207	Target Neighborhood Hits	325	Shared Neighborhood Hits	17
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB3_MOUSE
θ value	θ > 10 (rank : 445)	NC score	0.061424 (rank : 694)
Query Neighborhood Hits	207	Target Neighborhood Hits	319	Shared Neighborhood Hits	15
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB5_HUMAN
θ value	θ > 10 (rank : 446)	NC score	0.063018 (rank : 676)
Query Neighborhood Hits	207	Target Neighborhood Hits	310	Shared Neighborhood Hits	21
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB5_MOUSE
θ value	θ > 10 (rank : 447)	NC score	0.061610 (rank : 692)
Query Neighborhood Hits	207	Target Neighborhood Hits	329	Shared Neighborhood Hits	16
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB6_HUMAN
θ value	θ > 10 (rank : 448)	NC score	0.063059 (rank : 675)
Query Neighborhood Hits	207	Target Neighborhood Hits	318	Shared Neighborhood Hits	17
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB6_MOUSE
θ value	θ > 10 (rank : 449)	NC score	0.064385 (rank : 660)
Query Neighborhood Hits	207	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB7_HUMAN
θ value	θ > 10 (rank : 450)	NC score	0.059012 (rank : 722)
Query Neighborhood Hits	207	Target Neighborhood Hits	290	Shared Neighborhood Hits	17
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB7_MOUSE
θ value	θ > 10 (rank : 451)	NC score	0.056989 (rank : 741)
Query Neighborhood Hits	207	Target Neighborhood Hits	277	Shared Neighborhood Hits	17
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB8_HUMAN
θ value	θ > 10 (rank : 452)	NC score	0.063948 (rank : 667)
Query Neighborhood Hits	207	Target Neighborhood Hits	280	Shared Neighborhood Hits	20
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

ITK_HUMAN
θ value	θ > 10 (rank : 453)	NC score	0.090508 (rank : 498)
Query Neighborhood Hits	207	Target Neighborhood Hits	1016	Shared Neighborhood Hits	51
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

ITK_MOUSE
θ value	θ > 10 (rank : 454)	NC score	0.090752 (rank : 494)
Query Neighborhood Hits	207	Target Neighborhood Hits	985	Shared Neighborhood Hits	50
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

JAG1_HUMAN
θ value	θ > 10 (rank : 455)	NC score	0.054766 (rank : 774)
Query Neighborhood Hits	207	Target Neighborhood Hits	514	Shared Neighborhood Hits	22
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 456)	NC score	0.057375 (rank : 737)
Query Neighborhood Hits	207	Target Neighborhood Hits	518	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 457)	NC score	0.054090 (rank : 782)
Query Neighborhood Hits	207	Target Neighborhood Hits	491	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 458)	NC score	0.053845 (rank : 784)
Query Neighborhood Hits	207	Target Neighborhood Hits	504	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

JAK1_HUMAN
θ value	θ > 10 (rank : 459)	NC score	0.085735 (rank : 532)
Query Neighborhood Hits	207	Target Neighborhood Hits	858	Shared Neighborhood Hits	50
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

JAK1_MOUSE
θ value	θ > 10 (rank : 460)	NC score	0.085425 (rank : 535)
Query Neighborhood Hits	207	Target Neighborhood Hits	854	Shared Neighborhood Hits	50
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

JAK2_HUMAN
θ value	θ > 10 (rank : 461)	NC score	0.084028 (rank : 538)
Query Neighborhood Hits	207	Target Neighborhood Hits	847	Shared Neighborhood Hits	50
SwissProt Accessions	O60674, O14636, O75297	Gene names	JAK2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

JAK2_MOUSE
θ value	θ > 10 (rank : 462)	NC score	0.083258 (rank : 544)
Query Neighborhood Hits	207	Target Neighborhood Hits	839	Shared Neighborhood Hits	50
SwissProt Accessions	Q62120, Q62124	Gene names	Jak2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

JAK3_HUMAN
θ value	θ > 10 (rank : 463)	NC score	0.083626 (rank : 540)
Query Neighborhood Hits	207	Target Neighborhood Hits	827	Shared Neighborhood Hits	50
SwissProt Accessions	P52333, Q13259, Q13260, Q13611, Q9Y6S2	Gene names	JAK3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK).

JAK3_MOUSE
θ value	θ > 10 (rank : 464)	NC score	0.081058 (rank : 553)
Query Neighborhood Hits	207	Target Neighborhood Hits	821	Shared Neighborhood Hits	50
SwissProt Accessions	Q62137, Q61746, Q61747	Gene names	Jak3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3).

JAM1_HUMAN
θ value	θ > 10 (rank : 465)	NC score	0.295584 (rank : 157)
Query Neighborhood Hits	207	Target Neighborhood Hits	294	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

JAM1_MOUSE
θ value	θ > 10 (rank : 466)	NC score	0.283855 (rank : 168)
Query Neighborhood Hits	207	Target Neighborhood Hits	287	Shared Neighborhood Hits	75
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

JAM2_HUMAN
θ value	θ > 10 (rank : 467)	NC score	0.272734 (rank : 176)
Query Neighborhood Hits	207	Target Neighborhood Hits	304	Shared Neighborhood Hits	79
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

JAM2_MOUSE
θ value	θ > 10 (rank : 468)	NC score	0.258789 (rank : 192)
Query Neighborhood Hits	207	Target Neighborhood Hits	292	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

JAM3_HUMAN
θ value	θ > 10 (rank : 469)	NC score	0.306961 (rank : 147)
Query Neighborhood Hits	207	Target Neighborhood Hits	271	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

JAM3_MOUSE
θ value	θ > 10 (rank : 470)	NC score	0.304247 (rank : 149)
Query Neighborhood Hits	207	Target Neighborhood Hits	286	Shared Neighborhood Hits	73
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

JAML1_HUMAN
θ value	θ > 10 (rank : 471)	NC score	0.054546 (rank : 777)
Query Neighborhood Hits	207	Target Neighborhood Hits	108	Shared Neighborhood Hits	21
SwissProt Accessions	Q86YT9, Q5DTC6, Q7Z499, Q8N9I7, Q8NF70	Gene names	AMICA1, JAML
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (Dendritic cell-specific protein CREA7-1) (Adhesion molecule interacting with CXADR antigen 1).

JAML1_MOUSE
θ value	θ > 10 (rank : 472)	NC score	0.101983 (rank : 429)
Query Neighborhood Hits	207	Target Neighborhood Hits	185	Shared Neighborhood Hits	38
SwissProt Accessions	Q80UL9, Q5DTC4	Gene names	Amica1, Gm638, Jaml
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (mCrea7).

KAZD1_HUMAN
θ value	θ > 10 (rank : 473)	NC score	0.311930 (rank : 142)
Query Neighborhood Hits	207	Target Neighborhood Hits	248	Shared Neighborhood Hits	74
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

KAZD1_MOUSE
θ value	θ > 10 (rank : 474)	NC score	0.322505 (rank : 129)
Query Neighborhood Hits	207	Target Neighborhood Hits	281	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

KCC1A_HUMAN
θ value	θ > 10 (rank : 475)	NC score	0.051703 (rank : 824)
Query Neighborhood Hits	207	Target Neighborhood Hits	846	Shared Neighborhood Hits	50
SwissProt Accessions	Q14012	Gene names	CAMK1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

KCC1A_MOUSE
θ value	θ > 10 (rank : 476)	NC score	0.051778 (rank : 821)
Query Neighborhood Hits	207	Target Neighborhood Hits	845	Shared Neighborhood Hits	50
SwissProt Accessions	Q91YS8	Gene names	Camk1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

KIRR1_HUMAN
θ value	θ > 10 (rank : 477)	NC score	0.297656 (rank : 153)
Query Neighborhood Hits	207	Target Neighborhood Hits	401	Shared Neighborhood Hits	74
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

KIRR1_MOUSE
θ value	θ > 10 (rank : 478)	NC score	0.291810 (rank : 161)
Query Neighborhood Hits	207	Target Neighborhood Hits	403	Shared Neighborhood Hits	73
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

KIRR2_HUMAN
θ value	θ > 10 (rank : 479)	NC score	0.314275 (rank : 137)
Query Neighborhood Hits	207	Target Neighborhood Hits	321	Shared Neighborhood Hits	74
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

KIRR2_MOUSE
θ value	θ > 10 (rank : 480)	NC score	0.312130 (rank : 141)
Query Neighborhood Hits	207	Target Neighborhood Hits	326	Shared Neighborhood Hits	75
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

KIRR3_HUMAN
θ value	θ > 10 (rank : 481)	NC score	0.290296 (rank : 163)
Query Neighborhood Hits	207	Target Neighborhood Hits	302	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

KIRR3_MOUSE
θ value	θ > 10 (rank : 482)	NC score	0.284381 (rank : 167)
Query Neighborhood Hits	207	Target Neighborhood Hits	292	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

KIT_HUMAN
θ value	θ > 10 (rank : 483)	NC score	0.150965 (rank : 342)
Query Neighborhood Hits	207	Target Neighborhood Hits	953	Shared Neighborhood Hits	107
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KIT_MOUSE
θ value	θ > 10 (rank : 484)	NC score	0.160080 (rank : 316)
Query Neighborhood Hits	207	Target Neighborhood Hits	949	Shared Neighborhood Hits	108
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

KPSH2_HUMAN
θ value	θ > 10 (rank : 485)	NC score	0.050338 (rank : 849)
Query Neighborhood Hits	207	Target Neighborhood Hits	822	Shared Neighborhood Hits	50
SwissProt Accessions	Q96QS6	Gene names	PSKH2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase H2 (EC 2.7.11.1) (PSK-H2).

KR104_HUMAN
θ value	θ > 10 (rank : 486)	NC score	0.058131 (rank : 731)
Query Neighborhood Hits	207	Target Neighborhood Hits	313	Shared Neighborhood Hits	19
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR171_HUMAN
θ value	θ > 10 (rank : 487)	NC score	0.082099 (rank : 551)
Query Neighborhood Hits	207	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR510_HUMAN
θ value	θ > 10 (rank : 488)	NC score	0.052199 (rank : 811)
Query Neighborhood Hits	207	Target Neighborhood Hits	217	Shared Neighborhood Hits	15
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR511_HUMAN
θ value	θ > 10 (rank : 489)	NC score	0.073731 (rank : 591)
Query Neighborhood Hits	207	Target Neighborhood Hits	231	Shared Neighborhood Hits	15
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA44_HUMAN
θ value	θ > 10 (rank : 490)	NC score	0.050073 (rank : 857)
Query Neighborhood Hits	207	Target Neighborhood Hits	162	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA51_HUMAN
θ value	θ > 10 (rank : 491)	NC score	0.077357 (rank : 577)
Query Neighborhood Hits	207	Target Neighborhood Hits	288	Shared Neighborhood Hits	16
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 492)	NC score	0.069933 (rank : 626)
Query Neighborhood Hits	207	Target Neighborhood Hits	236	Shared Neighborhood Hits	16
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA53_HUMAN
θ value	θ > 10 (rank : 493)	NC score	0.077189 (rank : 578)
Query Neighborhood Hits	207	Target Neighborhood Hits	331	Shared Neighborhood Hits	23
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 494)	NC score	0.079940 (rank : 559)
Query Neighborhood Hits	207	Target Neighborhood Hits	270	Shared Neighborhood Hits	18
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
θ value	θ > 10 (rank : 495)	NC score	0.067333 (rank : 641)
Query Neighborhood Hits	207	Target Neighborhood Hits	257	Shared Neighborhood Hits	17
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA56_HUMAN
θ value	θ > 10 (rank : 496)	NC score	0.072496 (rank : 604)
Query Neighborhood Hits	207	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	θ > 10 (rank : 497)	NC score	0.082157 (rank : 549)
Query Neighborhood Hits	207	Target Neighborhood Hits	269	Shared Neighborhood Hits	17
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 498)	NC score	0.078962 (rank : 563)
Query Neighborhood Hits	207	Target Neighborhood Hits	324	Shared Neighborhood Hits	23
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 499)	NC score	0.079045 (rank : 562)
Query Neighborhood Hits	207	Target Neighborhood Hits	310	Shared Neighborhood Hits	18
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KS6A2_HUMAN
θ value	θ > 10 (rank : 500)	NC score	0.050290 (rank : 852)
Query Neighborhood Hits	207	Target Neighborhood Hits	857	Shared Neighborhood Hits	50
SwissProt Accessions	Q15349, Q15419, Q59GJ3, Q5TI68, Q96J38, Q9UJN5	Gene names	RPS6KA2, RSK3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C).

KS6A2_MOUSE
θ value	θ > 10 (rank : 501)	NC score	0.050492 (rank : 847)
Query Neighborhood Hits	207	Target Neighborhood Hits	858	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WUT3, Q9D2C0	Gene names	Rps6ka2, Rsk3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase- activated protein kinase 1c) (MAPKAPK1C).

KS6A3_HUMAN
θ value	θ > 10 (rank : 502)	NC score	0.050303 (rank : 851)
Query Neighborhood Hits	207	Target Neighborhood Hits	859	Shared Neighborhood Hits	50
SwissProt Accessions	P51812, Q4VAP3, Q59H26, Q5JPK8, Q7Z3Z7	Gene names	RPS6KA3, ISPK1, RSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

KS6A3_MOUSE
θ value	θ > 10 (rank : 503)	NC score	0.050276 (rank : 853)
Query Neighborhood Hits	207	Target Neighborhood Hits	860	Shared Neighborhood Hits	50
SwissProt Accessions	P18654, Q03140, Q8K3J8	Gene names	Rps6ka3, Rps6ka-rs1, Rsk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

KSR1_HUMAN
θ value	θ > 10 (rank : 504)	NC score	0.069721 (rank : 627)
Query Neighborhood Hits	207	Target Neighborhood Hits	867	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

KSR1_MOUSE
θ value	θ > 10 (rank : 505)	NC score	0.068926 (rank : 635)
Query Neighborhood Hits	207	Target Neighborhood Hits	870	Shared Neighborhood Hits	53
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

KSR2_HUMAN
θ value	θ > 10 (rank : 506)	NC score	0.061715 (rank : 691)
Query Neighborhood Hits	207	Target Neighborhood Hits	920	Shared Neighborhood Hits	50
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

KSYK_HUMAN
θ value	θ > 10 (rank : 507)	NC score	0.097107 (rank : 457)
Query Neighborhood Hits	207	Target Neighborhood Hits	901	Shared Neighborhood Hits	50
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

KSYK_MOUSE
θ value	θ > 10 (rank : 508)	NC score	0.096905 (rank : 459)
Query Neighborhood Hits	207	Target Neighborhood Hits	944	Shared Neighborhood Hits	50
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

LAG3_HUMAN
θ value	θ > 10 (rank : 509)	NC score	0.077424 (rank : 575)
Query Neighborhood Hits	207	Target Neighborhood Hits	129	Shared Neighborhood Hits	22
SwissProt Accessions	P18627	Gene names	LAG3, FDC
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (FDC protein) (CD223 antigen).

LAG3_MOUSE
θ value	θ > 10 (rank : 510)	NC score	0.083549 (rank : 541)
Query Neighborhood Hits	207	Target Neighborhood Hits	117	Shared Neighborhood Hits	30
SwissProt Accessions	Q61790, Q0VBL2	Gene names	Lag3
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (CD223 antigen).

LAMA1_HUMAN
θ value	θ > 10 (rank : 511)	NC score	0.059474 (rank : 715)
Query Neighborhood Hits	207	Target Neighborhood Hits	804	Shared Neighborhood Hits	44
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA1_MOUSE
θ value	θ > 10 (rank : 512)	NC score	0.062553 (rank : 678)
Query Neighborhood Hits	207	Target Neighborhood Hits	838	Shared Neighborhood Hits	44
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
θ value	θ > 10 (rank : 513)	NC score	0.055916 (rank : 756)
Query Neighborhood Hits	207	Target Neighborhood Hits	1092	Shared Neighborhood Hits	45
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA2_MOUSE
θ value	θ > 10 (rank : 514)	NC score	0.053327 (rank : 792)
Query Neighborhood Hits	207	Target Neighborhood Hits	1198	Shared Neighborhood Hits	43
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_MOUSE
θ value	θ > 10 (rank : 515)	NC score	0.059073 (rank : 720)
Query Neighborhood Hits	207	Target Neighborhood Hits	859	Shared Neighborhood Hits	34
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMA5_HUMAN
θ value	θ > 10 (rank : 516)	NC score	0.078921 (rank : 564)
Query Neighborhood Hits	207	Target Neighborhood Hits	976	Shared Neighborhood Hits	50
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_MOUSE
θ value	θ > 10 (rank : 517)	NC score	0.078251 (rank : 566)
Query Neighborhood Hits	207	Target Neighborhood Hits	828	Shared Neighborhood Hits	52
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB1_HUMAN
θ value	θ > 10 (rank : 518)	NC score	0.055038 (rank : 769)
Query Neighborhood Hits	207	Target Neighborhood Hits	1018	Shared Neighborhood Hits	29
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB1_MOUSE
θ value	θ > 10 (rank : 519)	NC score	0.058957 (rank : 723)
Query Neighborhood Hits	207	Target Neighborhood Hits	919	Shared Neighborhood Hits	28
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_HUMAN
θ value	θ > 10 (rank : 520)	NC score	0.064884 (rank : 658)
Query Neighborhood Hits	207	Target Neighborhood Hits	692	Shared Neighborhood Hits	38
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	θ > 10 (rank : 521)	NC score	0.062535 (rank : 679)
Query Neighborhood Hits	207	Target Neighborhood Hits	722	Shared Neighborhood Hits	34
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB3_HUMAN
θ value	θ > 10 (rank : 522)	NC score	0.064354 (rank : 661)
Query Neighborhood Hits	207	Target Neighborhood Hits	461	Shared Neighborhood Hits	16
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB3_MOUSE
θ value	θ > 10 (rank : 523)	NC score	0.065781 (rank : 654)
Query Neighborhood Hits	207	Target Neighborhood Hits	444	Shared Neighborhood Hits	15
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC1_HUMAN
θ value	θ > 10 (rank : 524)	NC score	0.050581 (rank : 845)
Query Neighborhood Hits	207	Target Neighborhood Hits	922	Shared Neighborhood Hits	33
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC1_MOUSE
θ value	θ > 10 (rank : 525)	NC score	0.054691 (rank : 775)
Query Neighborhood Hits	207	Target Neighborhood Hits	856	Shared Neighborhood Hits	36
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC2_MOUSE
θ value	θ > 10 (rank : 526)	NC score	0.050024 (rank : 859)
Query Neighborhood Hits	207	Target Neighborhood Hits	614	Shared Neighborhood Hits	39
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 527)	NC score	0.058343 (rank : 727)
Query Neighborhood Hits	207	Target Neighborhood Hits	588	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 528)	NC score	0.060150 (rank : 710)
Query Neighborhood Hits	207	Target Neighborhood Hits	624	Shared Neighborhood Hits	36
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LCK_HUMAN
θ value	θ > 10 (rank : 529)	NC score	0.090746 (rank : 495)
Query Neighborhood Hits	207	Target Neighborhood Hits	987	Shared Neighborhood Hits	53
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

LCK_MOUSE
θ value	θ > 10 (rank : 530)	NC score	0.090810 (rank : 492)
Query Neighborhood Hits	207	Target Neighborhood Hits	981	Shared Neighborhood Hits	51
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

LEPR_HUMAN
θ value	θ > 10 (rank : 531)	NC score	0.104285 (rank : 424)
Query Neighborhood Hits	207	Target Neighborhood Hits	112	Shared Neighborhood Hits	59
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

LEPR_MOUSE
θ value	θ > 10 (rank : 532)	NC score	0.097274 (rank : 455)
Query Neighborhood Hits	207	Target Neighborhood Hits	109	Shared Neighborhood Hits	50
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

LIMK1_HUMAN
θ value	θ > 10 (rank : 533)	NC score	0.069593 (rank : 628)
Query Neighborhood Hits	207	Target Neighborhood Hits	1005	Shared Neighborhood Hits	50
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

LIMK1_MOUSE
θ value	θ > 10 (rank : 534)	NC score	0.069018 (rank : 633)
Query Neighborhood Hits	207	Target Neighborhood Hits	1008	Shared Neighborhood Hits	50
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

LIMK2_HUMAN
θ value	θ > 10 (rank : 535)	NC score	0.072163 (rank : 606)
Query Neighborhood Hits	207	Target Neighborhood Hits	986	Shared Neighborhood Hits	50
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

LIMK2_MOUSE
θ value	θ > 10 (rank : 536)	NC score	0.072570 (rank : 602)
Query Neighborhood Hits	207	Target Neighborhood Hits	998	Shared Neighborhood Hits	50
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

LRC21_HUMAN
θ value	θ > 10 (rank : 537)	NC score	0.169653 (rank : 301)
Query Neighborhood Hits	207	Target Neighborhood Hits	456	Shared Neighborhood Hits	93
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRC21_MOUSE
θ value	θ > 10 (rank : 538)	NC score	0.176520 (rank : 286)
Query Neighborhood Hits	207	Target Neighborhood Hits	462	Shared Neighborhood Hits	97
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

LRC24_HUMAN
θ value	θ > 10 (rank : 539)	NC score	0.113000 (rank : 405)
Query Neighborhood Hits	207	Target Neighborhood Hits	404	Shared Neighborhood Hits	74
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRC24_MOUSE
θ value	θ > 10 (rank : 540)	NC score	0.095890 (rank : 464)
Query Neighborhood Hits	207	Target Neighborhood Hits	387	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

LRC4B_HUMAN
θ value	θ > 10 (rank : 541)	NC score	0.100479 (rank : 436)
Query Neighborhood Hits	207	Target Neighborhood Hits	479	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NT99, Q3ZCQ4, Q58F20	Gene names	LRRC4B, LRIG4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

LRC4B_MOUSE
θ value	θ > 10 (rank : 542)	NC score	0.102511 (rank : 427)
Query Neighborhood Hits	207	Target Neighborhood Hits	484	Shared Neighborhood Hits	73
SwissProt Accessions	P0C192	Gene names	Lrrc4b, Lrig4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

LRFN2_HUMAN
θ value	θ > 10 (rank : 543)	NC score	0.175041 (rank : 291)
Query Neighborhood Hits	207	Target Neighborhood Hits	450	Shared Neighborhood Hits	82
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN2_MOUSE
θ value	θ > 10 (rank : 544)	NC score	0.177196 (rank : 285)
Query Neighborhood Hits	207	Target Neighborhood Hits	450	Shared Neighborhood Hits	84
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRFN3_HUMAN
θ value	θ > 10 (rank : 545)	NC score	0.164615 (rank : 309)
Query Neighborhood Hits	207	Target Neighborhood Hits	444	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRFN3_MOUSE
θ value	θ > 10 (rank : 546)	NC score	0.173386 (rank : 294)
Query Neighborhood Hits	207	Target Neighborhood Hits	455	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

LRFN4_HUMAN
θ value	θ > 10 (rank : 547)	NC score	0.187744 (rank : 272)
Query Neighborhood Hits	207	Target Neighborhood Hits	462	Shared Neighborhood Hits	91
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRFN4_MOUSE
θ value	θ > 10 (rank : 548)	NC score	0.181606 (rank : 278)
Query Neighborhood Hits	207	Target Neighborhood Hits	442	Shared Neighborhood Hits	86
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

LRFN5_HUMAN
θ value	θ > 10 (rank : 549)	NC score	0.155286 (rank : 327)
Query Neighborhood Hits	207	Target Neighborhood Hits	464	Shared Neighborhood Hits	80
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRFN5_MOUSE
θ value	θ > 10 (rank : 550)	NC score	0.159105 (rank : 320)
Query Neighborhood Hits	207	Target Neighborhood Hits	472	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

LRIG1_HUMAN
θ value	θ > 10 (rank : 551)	NC score	0.273630 (rank : 174)
Query Neighborhood Hits	207	Target Neighborhood Hits	654	Shared Neighborhood Hits	88
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG1_MOUSE
θ value	θ > 10 (rank : 552)	NC score	0.268520 (rank : 182)
Query Neighborhood Hits	207	Target Neighborhood Hits	627	Shared Neighborhood Hits	87
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG2_HUMAN
θ value	θ > 10 (rank : 553)	NC score	0.274433 (rank : 172)
Query Neighborhood Hits	207	Target Neighborhood Hits	595	Shared Neighborhood Hits	91
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

LRIG2_MOUSE
θ value	θ > 10 (rank : 554)	NC score	0.274128 (rank : 173)
Query Neighborhood Hits	207	Target Neighborhood Hits	586	Shared Neighborhood Hits	91
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

LRIG3_HUMAN
θ value	θ > 10 (rank : 555)	NC score	0.263852 (rank : 185)
Query Neighborhood Hits	207	Target Neighborhood Hits	601	Shared Neighborhood Hits	92
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

LRIG3_MOUSE
θ value	θ > 10 (rank : 556)	NC score	0.266022 (rank : 183)
Query Neighborhood Hits	207	Target Neighborhood Hits	611	Shared Neighborhood Hits	91
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

LRP1B_HUMAN
θ value	θ > 10 (rank : 557)	NC score	0.051824 (rank : 820)
Query Neighborhood Hits	207	Target Neighborhood Hits	602	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRP1B_MOUSE
θ value	θ > 10 (rank : 558)	NC score	0.052648 (rank : 804)
Query Neighborhood Hits	207	Target Neighborhood Hits	606	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

LRRC4_HUMAN
θ value	θ > 10 (rank : 559)	NC score	0.088659 (rank : 519)
Query Neighborhood Hits	207	Target Neighborhood Hits	444	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

LRRC4_MOUSE
θ value	θ > 10 (rank : 560)	NC score	0.073277 (rank : 594)
Query Neighborhood Hits	207	Target Neighborhood Hits	412	Shared Neighborhood Hits	66
SwissProt Accessions	Q99PH1, Q8VI35	Gene names	Lrrc4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing 4 protein precursor (Brain tumor- associated protein MBAG1).

LRRK1_HUMAN
θ value	θ > 10 (rank : 561)	NC score	0.060202 (rank : 709)
Query Neighborhood Hits	207	Target Neighborhood Hits	1237	Shared Neighborhood Hits	54
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

LRRK1_MOUSE
θ value	θ > 10 (rank : 562)	NC score	0.061176 (rank : 698)
Query Neighborhood Hits	207	Target Neighborhood Hits	1267	Shared Neighborhood Hits	54
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

LRRK2_HUMAN
θ value	θ > 10 (rank : 563)	NC score	0.054597 (rank : 776)
Query Neighborhood Hits	207	Target Neighborhood Hits	1382	Shared Neighborhood Hits	53
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

LRRK2_MOUSE
θ value	θ > 10 (rank : 564)	NC score	0.051247 (rank : 830)
Query Neighborhood Hits	207	Target Neighborhood Hits	1359	Shared Neighborhood Hits	54
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

LRRN1_HUMAN
θ value	θ > 10 (rank : 565)	NC score	0.150190 (rank : 346)
Query Neighborhood Hits	207	Target Neighborhood Hits	518	Shared Neighborhood Hits	97
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

LRRN1_MOUSE
θ value	θ > 10 (rank : 566)	NC score	0.143710 (rank : 356)
Query Neighborhood Hits	207	Target Neighborhood Hits	508	Shared Neighborhood Hits	94
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

LRRN3_HUMAN
θ value	θ > 10 (rank : 567)	NC score	0.145640 (rank : 354)
Query Neighborhood Hits	207	Target Neighborhood Hits	461	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

LRRN3_MOUSE
θ value	θ > 10 (rank : 568)	NC score	0.137346 (rank : 364)
Query Neighborhood Hits	207	Target Neighborhood Hits	455	Shared Neighborhood Hits	85
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

LRRN5_HUMAN
θ value	θ > 10 (rank : 569)	NC score	0.129745 (rank : 371)
Query Neighborhood Hits	207	Target Neighborhood Hits	493	Shared Neighborhood Hits	82
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

LSAMP_HUMAN
θ value	θ > 10 (rank : 570)	NC score	0.344484 (rank : 110)
Query Neighborhood Hits	207	Target Neighborhood Hits	347	Shared Neighborhood Hits	80
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

LSAMP_MOUSE
θ value	θ > 10 (rank : 571)	NC score	0.346951 (rank : 109)
Query Neighborhood Hits	207	Target Neighborhood Hits	344	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

LTK_HUMAN
θ value	θ > 10 (rank : 572)	NC score	0.109623 (rank : 408)
Query Neighborhood Hits	207	Target Neighborhood Hits	774	Shared Neighborhood Hits	52
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

LTK_MOUSE
θ value	θ > 10 (rank : 573)	NC score	0.108904 (rank : 412)
Query Neighborhood Hits	207	Target Neighborhood Hits	770	Shared Neighborhood Hits	51
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

LU_HUMAN
θ value	θ > 10 (rank : 574)	NC score	0.311802 (rank : 143)
Query Neighborhood Hits	207	Target Neighborhood Hits	283	Shared Neighborhood Hits	77
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

LYN_HUMAN
θ value	θ > 10 (rank : 575)	NC score	0.089521 (rank : 511)
Query Neighborhood Hits	207	Target Neighborhood Hits	1022	Shared Neighborhood Hits	51
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

LYN_MOUSE
θ value	θ > 10 (rank : 576)	NC score	0.089754 (rank : 506)
Query Neighborhood Hits	207	Target Neighborhood Hits	1023	Shared Neighborhood Hits	51
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

M3K10_HUMAN
θ value	θ > 10 (rank : 577)	NC score	0.073627 (rank : 592)
Query Neighborhood Hits	207	Target Neighborhood Hits	1071	Shared Neighborhood Hits	53
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

M3K11_HUMAN
θ value	θ > 10 (rank : 578)	NC score	0.072014 (rank : 609)
Query Neighborhood Hits	207	Target Neighborhood Hits	1136	Shared Neighborhood Hits	55
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

M3K12_HUMAN
θ value	θ > 10 (rank : 579)	NC score	0.073052 (rank : 595)
Query Neighborhood Hits	207	Target Neighborhood Hits	940	Shared Neighborhood Hits	52
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K12_MOUSE
θ value	θ > 10 (rank : 580)	NC score	0.073024 (rank : 596)
Query Neighborhood Hits	207	Target Neighborhood Hits	957	Shared Neighborhood Hits	52
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K13_HUMAN
θ value	θ > 10 (rank : 581)	NC score	0.072880 (rank : 598)
Query Neighborhood Hits	207	Target Neighborhood Hits	911	Shared Neighborhood Hits	51
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

M3K7_HUMAN
θ value	θ > 10 (rank : 582)	NC score	0.072522 (rank : 603)
Query Neighborhood Hits	207	Target Neighborhood Hits	892	Shared Neighborhood Hits	50
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

M3K7_MOUSE
θ value	θ > 10 (rank : 583)	NC score	0.072669 (rank : 601)
Query Neighborhood Hits	207	Target Neighborhood Hits	892	Shared Neighborhood Hits	50
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

M3K9_HUMAN
θ value	θ > 10 (rank : 584)	NC score	0.072831 (rank : 600)
Query Neighborhood Hits	207	Target Neighborhood Hits	1123	Shared Neighborhood Hits	52
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

M3KL4_HUMAN
θ value	θ > 10 (rank : 585)	NC score	0.074189 (rank : 588)
Query Neighborhood Hits	207	Target Neighborhood Hits	1087	Shared Neighborhood Hits	53
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

MAG_HUMAN
θ value	θ > 10 (rank : 586)	NC score	0.324595 (rank : 126)
Query Neighborhood Hits	207	Target Neighborhood Hits	278	Shared Neighborhood Hits	78
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MAG_MOUSE
θ value	θ > 10 (rank : 587)	NC score	0.323280 (rank : 127)
Query Neighborhood Hits	207	Target Neighborhood Hits	271	Shared Neighborhood Hits	78
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MALT1_HUMAN
θ value	θ > 10 (rank : 588)	NC score	0.331748 (rank : 119)
Query Neighborhood Hits	207	Target Neighborhood Hits	236	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

MAMC1_HUMAN
θ value	θ > 10 (rank : 589)	NC score	0.390524 (rank : 96)
Query Neighborhood Hits	207	Target Neighborhood Hits	357	Shared Neighborhood Hits	86
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC1_MOUSE
θ value	θ > 10 (rank : 590)	NC score	0.391059 (rank : 95)
Query Neighborhood Hits	207	Target Neighborhood Hits	357	Shared Neighborhood Hits	86
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MATK_HUMAN
θ value	θ > 10 (rank : 591)	NC score	0.091492 (rank : 488)
Query Neighborhood Hits	207	Target Neighborhood Hits	954	Shared Neighborhood Hits	50
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

MATK_MOUSE
θ value	θ > 10 (rank : 592)	NC score	0.090930 (rank : 491)
Query Neighborhood Hits	207	Target Neighborhood Hits	952	Shared Neighborhood Hits	50
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

MATN1_HUMAN
θ value	θ > 10 (rank : 593)	NC score	0.052157 (rank : 813)
Query Neighborhood Hits	207	Target Neighborhood Hits	191	Shared Neighborhood Hits	7
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	θ > 10 (rank : 594)	NC score	0.052366 (rank : 807)
Query Neighborhood Hits	207	Target Neighborhood Hits	186	Shared Neighborhood Hits	7
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MDGA1_HUMAN
θ value	θ > 10 (rank : 595)	NC score	0.386322 (rank : 99)
Query Neighborhood Hits	207	Target Neighborhood Hits	358	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

MEGF6_HUMAN
θ value	θ > 10 (rank : 596)	NC score	0.072019 (rank : 608)
Query Neighborhood Hits	207	Target Neighborhood Hits	671	Shared Neighborhood Hits	46
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MEGF8_HUMAN
θ value	θ > 10 (rank : 597)	NC score	0.056038 (rank : 754)
Query Neighborhood Hits	207	Target Neighborhood Hits	528	Shared Neighborhood Hits	32
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 598)	NC score	0.056612 (rank : 745)
Query Neighborhood Hits	207	Target Neighborhood Hits	520	Shared Neighborhood Hits	30
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
θ value	θ > 10 (rank : 599)	NC score	0.077996 (rank : 568)
Query Neighborhood Hits	207	Target Neighborhood Hits	557	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	θ > 10 (rank : 600)	NC score	0.069281 (rank : 629)
Query Neighborhood Hits	207	Target Neighborhood Hits	896	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MET_HUMAN
θ value	θ > 10 (rank : 601)	NC score	0.096289 (rank : 463)
Query Neighborhood Hits	207	Target Neighborhood Hits	831	Shared Neighborhood Hits	49
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MET_MOUSE
θ value	θ > 10 (rank : 602)	NC score	0.096451 (rank : 462)
Query Neighborhood Hits	207	Target Neighborhood Hits	844	Shared Neighborhood Hits	50
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MFA3L_HUMAN
θ value	θ > 10 (rank : 603)	NC score	0.269858 (rank : 179)
Query Neighborhood Hits	207	Target Neighborhood Hits	230	Shared Neighborhood Hits	75
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

MFA3L_MOUSE
θ value	θ > 10 (rank : 604)	NC score	0.226620 (rank : 230)
Query Neighborhood Hits	207	Target Neighborhood Hits	214	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

MFAP3_HUMAN
θ value	θ > 10 (rank : 605)	NC score	0.066042 (rank : 649)
Query Neighborhood Hits	207	Target Neighborhood Hits	91	Shared Neighborhood Hits	32
SwissProt Accessions	P55082, Q9NXA7	Gene names	MFAP3
Domain Architecture
Description	Microfibril-associated glycoprotein 3 precursor.

MFAP4_HUMAN
θ value	θ > 10 (rank : 606)	NC score	0.077534 (rank : 573)
Query Neighborhood Hits	207	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	P55083, Q6P680	Gene names	MFAP4
Domain Architecture
Description	Microfibril-associated glycoprotein 4 precursor.

MFAP4_MOUSE
θ value	θ > 10 (rank : 607)	NC score	0.077677 (rank : 572)
Query Neighborhood Hits	207	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D1H9, Q5NCN1	Gene names	Mfap4
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 4 precursor.

MLKL_HUMAN
θ value	θ > 10 (rank : 608)	NC score	0.079441 (rank : 560)
Query Neighborhood Hits	207	Target Neighborhood Hits	600	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MLKL_MOUSE
θ value	θ > 10 (rank : 609)	NC score	0.074179 (rank : 589)
Query Neighborhood Hits	207	Target Neighborhood Hits	707	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

MLTK_HUMAN
θ value	θ > 10 (rank : 610)	NC score	0.075330 (rank : 584)
Query Neighborhood Hits	207	Target Neighborhood Hits	911	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

MLTK_MOUSE
θ value	θ > 10 (rank : 611)	NC score	0.075478 (rank : 583)
Query Neighborhood Hits	207	Target Neighborhood Hits	874	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

MOS_HUMAN
θ value	θ > 10 (rank : 612)	NC score	0.071343 (rank : 616)
Query Neighborhood Hits	207	Target Neighborhood Hits	829	Shared Neighborhood Hits	50
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

MOS_MOUSE
θ value	θ > 10 (rank : 613)	NC score	0.062399 (rank : 683)
Query Neighborhood Hits	207	Target Neighborhood Hits	833	Shared Neighborhood Hits	50
SwissProt Accessions	P00536	Gene names	Mos
Domain Architecture	No domain graphic available
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

MOX2R_HUMAN
θ value	θ > 10 (rank : 614)	NC score	0.061372 (rank : 696)
Query Neighborhood Hits	207	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TD46, Q8TD44, Q8TD45, Q8TD52	Gene names	CD200R1, CD200R, CRTR2, MOX2R, OX2R
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

MOX2R_MOUSE
θ value	θ > 10 (rank : 615)	NC score	0.154386 (rank : 330)
Query Neighborhood Hits	207	Target Neighborhood Hits	110	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ES57	Gene names	Cd200r1, Mox2r, Ox2r
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

MP2K5_HUMAN
θ value	θ > 10 (rank : 616)	NC score	0.054318 (rank : 780)
Query Neighborhood Hits	207	Target Neighborhood Hits	837	Shared Neighborhood Hits	51
SwissProt Accessions	Q13163	Gene names	MAP2K5, MEK5, MKK5, PRKMK5
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 5 (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5).

MP2K5_MOUSE
θ value	θ > 10 (rank : 617)	NC score	0.053380 (rank : 791)
Query Neighborhood Hits	207	Target Neighborhood Hits	840	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WVS7, Q8CFM3, Q8K360, Q9D222	Gene names	Map2k5, Mek5, Mkk5, Prkmk5
Domain Architecture	No domain graphic available
Description	Dual specificity mitogen-activated protein kinase kinase 5 (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5).

MST4_HUMAN
θ value	θ > 10 (rank : 618)	NC score	0.056429 (rank : 747)
Query Neighborhood Hits	207	Target Neighborhood Hits	852	Shared Neighborhood Hits	50
SwissProt Accessions	Q9P289, Q3ZB77, Q9BXC4	Gene names	MST4, MASK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) (Serine/threonine-protein kinase MASK) (Mst3 and SOK1-related kinase).

MST4_MOUSE
θ value	θ > 10 (rank : 619)	NC score	0.056379 (rank : 748)
Query Neighborhood Hits	207	Target Neighborhood Hits	860	Shared Neighborhood Hits	50
SwissProt Accessions	Q99JT2	Gene names	Mst4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4).

MUC18_HUMAN
θ value	θ > 10 (rank : 620)	NC score	0.309773 (rank : 146)
Query Neighborhood Hits	207	Target Neighborhood Hits	275	Shared Neighborhood Hits	73
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

MUC18_MOUSE
θ value	θ > 10 (rank : 621)	NC score	0.295131 (rank : 158)
Query Neighborhood Hits	207	Target Neighborhood Hits	292	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

MUSK_HUMAN
θ value	θ > 10 (rank : 622)	NC score	0.275696 (rank : 171)
Query Neighborhood Hits	207	Target Neighborhood Hits	1074	Shared Neighborhood Hits	119
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

MUSK_MOUSE
θ value	θ > 10 (rank : 623)	NC score	0.276000 (rank : 170)
Query Neighborhood Hits	207	Target Neighborhood Hits	1057	Shared Neighborhood Hits	119
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

MYLK2_HUMAN
θ value	θ > 10 (rank : 624)	NC score	0.061030 (rank : 701)
Query Neighborhood Hits	207	Target Neighborhood Hits	920	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

MYOTI_HUMAN
θ value	θ > 10 (rank : 625)	NC score	0.411018 (rank : 86)
Query Neighborhood Hits	207	Target Neighborhood Hits	292	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

MYOTI_MOUSE
θ value	θ > 10 (rank : 626)	NC score	0.412689 (rank : 85)
Query Neighborhood Hits	207	Target Neighborhood Hits	297	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

MYPN_HUMAN
θ value	θ > 10 (rank : 627)	NC score	0.415421 (rank : 83)
Query Neighborhood Hits	207	Target Neighborhood Hits	418	Shared Neighborhood Hits	85
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

MYPN_MOUSE
θ value	θ > 10 (rank : 628)	NC score	0.409845 (rank : 87)
Query Neighborhood Hits	207	Target Neighborhood Hits	421	Shared Neighborhood Hits	83
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

NAGPA_HUMAN
θ value	θ > 10 (rank : 629)	NC score	0.088092 (rank : 522)
Query Neighborhood Hits	207	Target Neighborhood Hits	282	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NAGPA_MOUSE
θ value	θ > 10 (rank : 630)	NC score	0.091766 (rank : 486)
Query Neighborhood Hits	207	Target Neighborhood Hits	308	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NEGR1_HUMAN
θ value	θ > 10 (rank : 631)	NC score	0.344368 (rank : 111)
Query Neighborhood Hits	207	Target Neighborhood Hits	346	Shared Neighborhood Hits	79
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

NEGR1_MOUSE
θ value	θ > 10 (rank : 632)	NC score	0.341693 (rank : 113)
Query Neighborhood Hits	207	Target Neighborhood Hits	349	Shared Neighborhood Hits	80
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

NEK11_HUMAN
θ value	θ > 10 (rank : 633)	NC score	0.058220 (rank : 730)
Query Neighborhood Hits	207	Target Neighborhood Hits	1043	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

NEK11_MOUSE
θ value	θ > 10 (rank : 634)	NC score	0.059253 (rank : 717)
Query Neighborhood Hits	207	Target Neighborhood Hits	875	Shared Neighborhood Hits	50
SwissProt Accessions	Q8C0Q4, Q8BLS6, Q8BW62	Gene names	Nek11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

NEK4_HUMAN
θ value	θ > 10 (rank : 635)	NC score	0.053736 (rank : 785)
Query Neighborhood Hits	207	Target Neighborhood Hits	883	Shared Neighborhood Hits	50
SwissProt Accessions	P51957	Gene names	NEK4, STK2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2).

NEK4_MOUSE
θ value	θ > 10 (rank : 636)	NC score	0.053720 (rank : 786)
Query Neighborhood Hits	207	Target Neighborhood Hits	899	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z1J2, O35673, Q9R1J1	Gene names	Nek4, Stk2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2).

NEK6_HUMAN
θ value	θ > 10 (rank : 637)	NC score	0.052852 (rank : 800)
Query Neighborhood Hits	207	Target Neighborhood Hits	848	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HC98, Q96E83, Q9ULX2	Gene names	NEK6
Domain Architecture
Description	Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (NimA-related protein kinase 6) (Protein kinase SID6-1512).

NEK6_MOUSE
θ value	θ > 10 (rank : 638)	NC score	0.052667 (rank : 801)
Query Neighborhood Hits	207	Target Neighborhood Hits	851	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ES70, Q3TCE9, Q8C6E6, Q9D0E2, Q9DBI8	Gene names	Nek6
Domain Architecture
Description	Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (NimA-related protein kinase 6).

NEK7_HUMAN
θ value	θ > 10 (rank : 639)	NC score	0.054038 (rank : 783)
Query Neighborhood Hits	207	Target Neighborhood Hits	846	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TDX7	Gene names	NEK7
Domain Architecture
Description	Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (NimA-related protein kinase 7).

NEK7_MOUSE
θ value	θ > 10 (rank : 640)	NC score	0.054278 (rank : 781)
Query Neighborhood Hits	207	Target Neighborhood Hits	847	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ES74, Q3UEV7	Gene names	Nek7
Domain Architecture
Description	Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (NimA-related protein kinase 7).

NEK9_HUMAN
θ value	θ > 10 (rank : 641)	NC score	0.050321 (rank : 850)
Query Neighborhood Hits	207	Target Neighborhood Hits	900	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TD19, Q52LK6, Q8NCN0, Q8TCY4, Q9UPI4, Q9Y6S4, Q9Y6S5, Q9Y6S6	Gene names	NEK9, KIAA1995, NEK8, NERCC
Domain Architecture
Description	Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8).

NGL1_HUMAN
θ value	θ > 10 (rank : 642)	NC score	0.098297 (rank : 449)
Query Neighborhood Hits	207	Target Neighborhood Hits	511	Shared Neighborhood Hits	70
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NGL1_MOUSE
θ value	θ > 10 (rank : 643)	NC score	0.098512 (rank : 447)
Query Neighborhood Hits	207	Target Neighborhood Hits	512	Shared Neighborhood Hits	70
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

NIM1_HUMAN
θ value	θ > 10 (rank : 644)	NC score	0.051454 (rank : 826)
Query Neighborhood Hits	207	Target Neighborhood Hits	850	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IY84	Gene names	NIM1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase NIM1 (EC 2.7.11.1).

NPTN_HUMAN
θ value	θ > 10 (rank : 645)	NC score	0.332641 (rank : 117)
Query Neighborhood Hits	207	Target Neighborhood Hits	212	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

NPTN_MOUSE
θ value	θ > 10 (rank : 646)	NC score	0.320486 (rank : 132)
Query Neighborhood Hits	207	Target Neighborhood Hits	216	Shared Neighborhood Hits	74
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

NRG1_HUMAN
θ value	θ > 10 (rank : 647)	NC score	0.197172 (rank : 265)
Query Neighborhood Hits	207	Target Neighborhood Hits	285	Shared Neighborhood Hits	68
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

NTNG2_HUMAN
θ value	θ > 10 (rank : 648)	NC score	0.052663 (rank : 802)
Query Neighborhood Hits	207	Target Neighborhood Hits	276	Shared Neighborhood Hits	20
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NTNG2_MOUSE
θ value	θ > 10 (rank : 649)	NC score	0.050929 (rank : 835)
Query Neighborhood Hits	207	Target Neighborhood Hits	276	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

NTRI_HUMAN
θ value	θ > 10 (rank : 650)	NC score	0.325505 (rank : 124)
Query Neighborhood Hits	207	Target Neighborhood Hits	344	Shared Neighborhood Hits	80
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

NTRI_MOUSE
θ value	θ > 10 (rank : 651)	NC score	0.329602 (rank : 121)
Query Neighborhood Hits	207	Target Neighborhood Hits	342	Shared Neighborhood Hits	81
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

NTRK1_HUMAN
θ value	θ > 10 (rank : 652)	NC score	0.126256 (rank : 376)
Query Neighborhood Hits	207	Target Neighborhood Hits	1023	Shared Neighborhood Hits	99
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

NTRK2_HUMAN
θ value	θ > 10 (rank : 653)	NC score	0.176206 (rank : 287)
Query Neighborhood Hits	207	Target Neighborhood Hits	1081	Shared Neighborhood Hits	117
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

NTRK2_MOUSE
θ value	θ > 10 (rank : 654)	NC score	0.175636 (rank : 288)
Query Neighborhood Hits	207	Target Neighborhood Hits	1088	Shared Neighborhood Hits	118
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

NTRK3_HUMAN
θ value	θ > 10 (rank : 655)	NC score	0.174992 (rank : 292)
Query Neighborhood Hits	207	Target Neighborhood Hits	1115	Shared Neighborhood Hits	119
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

NUAK1_HUMAN
θ value	θ > 10 (rank : 656)	NC score	0.051150 (rank : 832)
Query Neighborhood Hits	207	Target Neighborhood Hits	874	Shared Neighborhood Hits	50
SwissProt Accessions	O60285, Q96KA8	Gene names	NUAK1, ARK5, KIAA0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5).

NUAK1_MOUSE
θ value	θ > 10 (rank : 657)	NC score	0.050628 (rank : 843)
Query Neighborhood Hits	207	Target Neighborhood Hits	881	Shared Neighborhood Hits	50
SwissProt Accessions	Q641K5, Q6I6D6, Q8CGE1	Gene names	Nuak1, Kiaa0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1).

NUAK2_HUMAN
θ value	θ > 10 (rank : 658)	NC score	0.050840 (rank : 837)
Query Neighborhood Hits	207	Target Neighborhood Hits	874	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H093	Gene names	NUAK2
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (SNF1/AMP kinase-related kinase) (SNARK).

OBSL1_HUMAN
θ value	θ > 10 (rank : 659)	NC score	0.446428 (rank : 76)
Query Neighborhood Hits	207	Target Neighborhood Hits	354	Shared Neighborhood Hits	85
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

OPCM_HUMAN
θ value	θ > 10 (rank : 660)	NC score	0.338358 (rank : 115)
Query Neighborhood Hits	207	Target Neighborhood Hits	332	Shared Neighborhood Hits	81
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

OX2G_HUMAN
θ value	θ > 10 (rank : 661)	NC score	0.080363 (rank : 556)
Query Neighborhood Hits	207	Target Neighborhood Hits	100	Shared Neighborhood Hits	30
SwissProt Accessions	P41217, Q6J2Q6, Q6PIQ4, Q8TB85, Q9H3J3	Gene names	CD200, MOX2
Domain Architecture
Description	OX-2 membrane glycoprotein precursor (CD200 antigen).

OX2G_MOUSE
θ value	θ > 10 (rank : 662)	NC score	0.085325 (rank : 536)
Query Neighborhood Hits	207	Target Neighborhood Hits	105	Shared Neighborhood Hits	32
SwissProt Accessions	O54901, O54816, Q9JHD5	Gene names	Cd200, Mox2
Domain Architecture
Description	OX-2 membrane glycoprotein precursor (MRC OX-2 antigen) (CD200 antigen).

PAK6_HUMAN
θ value	θ > 10 (rank : 663)	NC score	0.052384 (rank : 806)
Query Neighborhood Hits	207	Target Neighborhood Hits	915	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

PAK7_HUMAN
θ value	θ > 10 (rank : 664)	NC score	0.051251 (rank : 829)
Query Neighborhood Hits	207	Target Neighborhood Hits	875	Shared Neighborhood Hits	50
SwissProt Accessions	Q9P286, Q5W115, Q9BX09, Q9ULF6	Gene names	PAK7, KIAA1264, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (PAK-5).

PAK7_MOUSE
θ value	θ > 10 (rank : 665)	NC score	0.051134 (rank : 833)
Query Neighborhood Hits	207	Target Neighborhood Hits	875	Shared Neighborhood Hits	50
SwissProt Accessions	Q8C015, Q3TQJ7, Q6RWS7	Gene names	Pak7, Pak5
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5).

PDL1_HUMAN
θ value	θ > 10 (rank : 666)	NC score	0.137328 (rank : 365)
Query Neighborhood Hits	207	Target Neighborhood Hits	195	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL1_MOUSE
θ value	θ > 10 (rank : 667)	NC score	0.104874 (rank : 422)
Query Neighborhood Hits	207	Target Neighborhood Hits	168	Shared Neighborhood Hits	48
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

PDL2_HUMAN
θ value	θ > 10 (rank : 668)	NC score	0.071973 (rank : 610)
Query Neighborhood Hits	207	Target Neighborhood Hits	114	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PDL2_MOUSE
θ value	θ > 10 (rank : 669)	NC score	0.114767 (rank : 404)
Query Neighborhood Hits	207	Target Neighborhood Hits	116	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

PECA1_HUMAN
θ value	θ > 10 (rank : 670)	NC score	0.128385 (rank : 372)
Query Neighborhood Hits	207	Target Neighborhood Hits	178	Shared Neighborhood Hits	50
SwissProt Accessions	P16284, Q6LDA9, Q8TBH1, Q96RF5, Q96RF6, Q9NP65, Q9NPB7, Q9NPG9, Q9NQS9, Q9NQT0, Q9NQT1, Q9NQT2	Gene names	PECAM1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (EndoCAM) (GPIIA') (CD31 antigen).

PECA1_MOUSE
θ value	θ > 10 (rank : 671)	NC score	0.103270 (rank : 426)
Query Neighborhood Hits	207	Target Neighborhood Hits	126	Shared Neighborhood Hits	38
SwissProt Accessions	Q08481	Gene names	Pecam1, Pecam, Pecam-1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (CD31 antigen).

PGBM_HUMAN
θ value	θ > 10 (rank : 672)	NC score	0.326207 (rank : 123)
Query Neighborhood Hits	207	Target Neighborhood Hits	1113	Shared Neighborhood Hits	119
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	θ > 10 (rank : 673)	NC score	0.317494 (rank : 134)
Query Neighborhood Hits	207	Target Neighborhood Hits	1073	Shared Neighborhood Hits	119
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGFRA_HUMAN
θ value	θ > 10 (rank : 674)	NC score	0.168783 (rank : 303)
Query Neighborhood Hits	207	Target Neighborhood Hits	980	Shared Neighborhood Hits	110
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRA_MOUSE
θ value	θ > 10 (rank : 675)	NC score	0.167614 (rank : 304)
Query Neighborhood Hits	207	Target Neighborhood Hits	975	Shared Neighborhood Hits	109
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRB_HUMAN
θ value	θ > 10 (rank : 676)	NC score	0.150221 (rank : 345)
Query Neighborhood Hits	207	Target Neighborhood Hits	962	Shared Neighborhood Hits	109
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PGFRB_MOUSE
θ value	θ > 10 (rank : 677)	NC score	0.157351 (rank : 323)
Query Neighborhood Hits	207	Target Neighborhood Hits	960	Shared Neighborhood Hits	104
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PGFRL_HUMAN
θ value	θ > 10 (rank : 678)	NC score	0.134272 (rank : 370)
Query Neighborhood Hits	207	Target Neighborhood Hits	115	Shared Neighborhood Hits	49
SwissProt Accessions	Q15198, Q6FH04	Gene names	PDGFRL, PRLTS
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor (PDGF receptor beta-like tumor suppressor).

PGFRL_MOUSE
θ value	θ > 10 (rank : 679)	NC score	0.100532 (rank : 435)
Query Neighborhood Hits	207	Target Neighborhood Hits	106	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PE55, Q3V182, Q9D0Z1	Gene names	Pdgfrl
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor.

PIGR_HUMAN
θ value	θ > 10 (rank : 680)	NC score	0.151054 (rank : 341)
Query Neighborhood Hits	207	Target Neighborhood Hits	164	Shared Neighborhood Hits	47
SwissProt Accessions	P01833, Q8IZY7	Gene names	PIGR
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) (Hepatocellular carcinoma-associated protein TB6) [Contains: Secretory component].

PIGR_MOUSE
θ value	θ > 10 (rank : 681)	NC score	0.150720 (rank : 344)
Query Neighborhood Hits	207	Target Neighborhood Hits	214	Shared Neighborhood Hits	47
SwissProt Accessions	O70570	Gene names	Pigr
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) [Contains: Secretory component].

PLK4_HUMAN
θ value	θ > 10 (rank : 682)	NC score	0.051997 (rank : 816)
Query Neighborhood Hits	207	Target Neighborhood Hits	884	Shared Neighborhood Hits	52
SwissProt Accessions	O00444, Q8IYF0, Q96Q95	Gene names	PLK4, SAK, STK18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

PLK4_MOUSE
θ value	θ > 10 (rank : 683)	NC score	0.051986 (rank : 817)
Query Neighborhood Hits	207	Target Neighborhood Hits	879	Shared Neighborhood Hits	50
SwissProt Accessions	Q64702, Q6PEP6, Q78EG6, Q8R0I5, Q9CVR6, Q9CVU6	Gene names	Plk4, Sak, Stk18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

PRLR_HUMAN
θ value	θ > 10 (rank : 684)	NC score	0.073309 (rank : 593)
Query Neighborhood Hits	207	Target Neighborhood Hits	95	Shared Neighborhood Hits	38
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

PRLR_MOUSE
θ value	θ > 10 (rank : 685)	NC score	0.063704 (rank : 669)
Query Neighborhood Hits	207	Target Neighborhood Hits	82	Shared Neighborhood Hits	33
SwissProt Accessions	Q08501, P15212, P15213, Q62099	Gene names	Prlr
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

PRPE_HUMAN
θ value	θ > 10 (rank : 686)	NC score	0.074971 (rank : 586)
Query Neighborhood Hits	207	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

PSG10_HUMAN
θ value	θ > 10 (rank : 687)	NC score	0.149359 (rank : 348)
Query Neighborhood Hits	207	Target Neighborhood Hits	227	Shared Neighborhood Hits	62
SwissProt Accessions	Q15235, O75244, Q15224	Gene names	PSG10, PSG12
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 10 precursor (PSBG-10) (PSBG- 12).

PSG11_HUMAN
θ value	θ > 10 (rank : 688)	NC score	0.154813 (rank : 329)
Query Neighborhood Hits	207	Target Neighborhood Hits	223	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UQ72, Q13179, Q15242, Q9UNE4	Gene names	PSG11, PSG13
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 11 precursor (PSBG-11) (PSBG- 13).

PSG1_HUMAN
θ value	θ > 10 (rank : 689)	NC score	0.157126 (rank : 324)
Query Neighborhood Hits	207	Target Neighborhood Hits	232	Shared Neighborhood Hits	65
SwissProt Accessions	P11464, O75236, P11462, P11463, Q15231, Q15241, Q15243, Q16660, Q9P1W5, Q9UQ79	Gene names	PSG1, B1G1, PSGGA
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 1 precursor (PSBG-1) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (CD66f antigen).

PSG2_HUMAN
θ value	θ > 10 (rank : 690)	NC score	0.149077 (rank : 350)
Query Neighborhood Hits	207	Target Neighborhood Hits	229	Shared Neighborhood Hits	64
SwissProt Accessions	P11465, Q8TCD9, Q9UEA4, Q9UQ78	Gene names	PSG2
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 2 precursor (PSBG-2) (Pregnancy-specific beta-1 glycoprotein E) (PS-beta-E).

PSG3_HUMAN
θ value	θ > 10 (rank : 691)	NC score	0.171245 (rank : 296)
Query Neighborhood Hits	207	Target Neighborhood Hits	242	Shared Neighborhood Hits	69
SwissProt Accessions	Q16557, Q08265, Q9BRW2, Q9UPL4, Q9UQ77	Gene names	PSG3
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 3 precursor (PSBG-3) (Carcinoembryonic antigen SG5).

PSG4_HUMAN
θ value	θ > 10 (rank : 692)	NC score	0.165784 (rank : 307)
Query Neighborhood Hits	207	Target Neighborhood Hits	243	Shared Neighborhood Hits	64
SwissProt Accessions	Q00888, Q13047, Q13048, Q15234, Q15240, Q9UQ76	Gene names	PSG4, CGM4, PSG9
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 4 precursor (PSBG-4) (PSBG-9).

PSG5_HUMAN
θ value	θ > 10 (rank : 693)	NC score	0.134517 (rank : 369)
Query Neighborhood Hits	207	Target Neighborhood Hits	231	Shared Neighborhood Hits	64
SwissProt Accessions	Q15238, Q15239, Q96QJ1, Q9UQ75	Gene names	PSG5
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 5 precursor (PSBG-5) (Fetal liver non-specific cross-reactive antigen 3) (FL-NCA-3).

PSG6_HUMAN
θ value	θ > 10 (rank : 694)	NC score	0.151716 (rank : 340)
Query Neighborhood Hits	207	Target Neighborhood Hits	231	Shared Neighborhood Hits	62
SwissProt Accessions	Q00889	Gene names	PSG6, CGM3, PSGGB
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 6 precursor (PSBG-6).

PSG7_HUMAN
θ value	θ > 10 (rank : 695)	NC score	0.158984 (rank : 321)
Query Neighborhood Hits	207	Target Neighborhood Hits	239	Shared Neighborhood Hits	64
SwissProt Accessions	Q13046, Q15232	Gene names	PSG7
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 7 precursor (PSBG-7).

PSG8_HUMAN
θ value	θ > 10 (rank : 696)	NC score	0.167176 (rank : 305)
Query Neighborhood Hits	207	Target Neighborhood Hits	239	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UQ74, O60410	Gene names	PSG8
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 8 precursor (PSBG-8).

PSG9_HUMAN
θ value	θ > 10 (rank : 697)	NC score	0.140275 (rank : 361)
Query Neighborhood Hits	207	Target Neighborhood Hits	221	Shared Neighborhood Hits	61
SwissProt Accessions	Q00887, Q15236, Q15237, Q8WW78, Q9UQ73	Gene names	PSG9, PSG11
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 9 precursor (PSBG-9) (Pregnancy-specific glycoprotein 9) (Pregnancy-specific beta-1 glycoprotein B) (PS-beta-B) (PS34) (Pregnancy-specific glycoprotein 7) (PSG7).

PTK6_HUMAN
θ value	θ > 10 (rank : 698)	NC score	0.086805 (rank : 527)
Query Neighborhood Hits	207	Target Neighborhood Hits	1020	Shared Neighborhood Hits	51
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

PTK6_MOUSE
θ value	θ > 10 (rank : 699)	NC score	0.088380 (rank : 521)
Query Neighborhood Hits	207	Target Neighborhood Hits	1026	Shared Neighborhood Hits	51
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

PTK7_HUMAN
θ value	θ > 10 (rank : 700)	NC score	0.295594 (rank : 156)
Query Neighborhood Hits	207	Target Neighborhood Hits	1103	Shared Neighborhood Hits	118
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

PTN11_HUMAN
θ value	θ > 10 (rank : 701)	NC score	0.108964 (rank : 410)
Query Neighborhood Hits	207	Target Neighborhood Hits	227	Shared Neighborhood Hits	15
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 702)	NC score	0.108956 (rank : 411)
Query Neighborhood Hits	207	Target Neighborhood Hits	227	Shared Neighborhood Hits	15
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN12_HUMAN
θ value	θ > 10 (rank : 703)	NC score	0.116408 (rank : 399)
Query Neighborhood Hits	207	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
θ value	θ > 10 (rank : 704)	NC score	0.115897 (rank : 402)
Query Neighborhood Hits	207	Target Neighborhood Hits	123	Shared Neighborhood Hits	15
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN13_HUMAN
θ value	θ > 10 (rank : 705)	NC score	0.085672 (rank : 533)
Query Neighborhood Hits	207	Target Neighborhood Hits	471	Shared Neighborhood Hits	16
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN13_MOUSE
θ value	θ > 10 (rank : 706)	NC score	0.087300 (rank : 524)
Query Neighborhood Hits	207	Target Neighborhood Hits	426	Shared Neighborhood Hits	17
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN14_HUMAN
θ value	θ > 10 (rank : 707)	NC score	0.094987 (rank : 468)
Query Neighborhood Hits	207	Target Neighborhood Hits	163	Shared Neighborhood Hits	16
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN14_MOUSE
θ value	θ > 10 (rank : 708)	NC score	0.094614 (rank : 471)
Query Neighborhood Hits	207	Target Neighborhood Hits	142	Shared Neighborhood Hits	16
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN18_HUMAN
θ value	θ > 10 (rank : 709)	NC score	0.116289 (rank : 400)
Query Neighborhood Hits	207	Target Neighborhood Hits	73	Shared Neighborhood Hits	15
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN18_MOUSE
θ value	θ > 10 (rank : 710)	NC score	0.117742 (rank : 398)
Query Neighborhood Hits	207	Target Neighborhood Hits	134	Shared Neighborhood Hits	15
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN1_HUMAN
θ value	θ > 10 (rank : 711)	NC score	0.119205 (rank : 393)
Query Neighborhood Hits	207	Target Neighborhood Hits	84	Shared Neighborhood Hits	15
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN1_MOUSE
θ value	θ > 10 (rank : 712)	NC score	0.118992 (rank : 395)
Query Neighborhood Hits	207	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN21_HUMAN
θ value	θ > 10 (rank : 713)	NC score	0.093838 (rank : 476)
Query Neighborhood Hits	207	Target Neighborhood Hits	143	Shared Neighborhood Hits	15
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN21_MOUSE
θ value	θ > 10 (rank : 714)	NC score	0.094676 (rank : 470)
Query Neighborhood Hits	207	Target Neighborhood Hits	155	Shared Neighborhood Hits	17
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN22_HUMAN
θ value	θ > 10 (rank : 715)	NC score	0.118640 (rank : 396)
Query Neighborhood Hits	207	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN22_MOUSE
θ value	θ > 10 (rank : 716)	NC score	0.115934 (rank : 401)
Query Neighborhood Hits	207	Target Neighborhood Hits	179	Shared Neighborhood Hits	16
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN23_HUMAN
θ value	θ > 10 (rank : 717)	NC score	0.095739 (rank : 465)
Query Neighborhood Hits	207	Target Neighborhood Hits	646	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	θ > 10 (rank : 718)	NC score	0.098189 (rank : 450)
Query Neighborhood Hits	207	Target Neighborhood Hits	726	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN2_HUMAN
θ value	θ > 10 (rank : 719)	NC score	0.121131 (rank : 384)
Query Neighborhood Hits	207	Target Neighborhood Hits	92	Shared Neighborhood Hits	15
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN2_MOUSE
θ value	θ > 10 (rank : 720)	NC score	0.120227 (rank : 385)
Query Neighborhood Hits	207	Target Neighborhood Hits	107	Shared Neighborhood Hits	15
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN3_HUMAN
θ value	θ > 10 (rank : 721)	NC score	0.093012 (rank : 478)
Query Neighborhood Hits	207	Target Neighborhood Hits	258	Shared Neighborhood Hits	18
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN4_HUMAN
θ value	θ > 10 (rank : 722)	NC score	0.090167 (rank : 500)
Query Neighborhood Hits	207	Target Neighborhood Hits	303	Shared Neighborhood Hits	16
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN5_HUMAN
θ value	θ > 10 (rank : 723)	NC score	0.121946 (rank : 382)
Query Neighborhood Hits	207	Target Neighborhood Hits	80	Shared Neighborhood Hits	15
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_MOUSE
θ value	θ > 10 (rank : 724)	NC score	0.121958 (rank : 381)
Query Neighborhood Hits	207	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN6_HUMAN
θ value	θ > 10 (rank : 725)	NC score	0.111489 (rank : 407)
Query Neighborhood Hits	207	Target Neighborhood Hits	234	Shared Neighborhood Hits	15
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
θ value	θ > 10 (rank : 726)	NC score	0.111567 (rank : 406)
Query Neighborhood Hits	207	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN7_HUMAN
θ value	θ > 10 (rank : 727)	NC score	0.121879 (rank : 383)
Query Neighborhood Hits	207	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN7_MOUSE
θ value	θ > 10 (rank : 728)	NC score	0.122029 (rank : 380)
Query Neighborhood Hits	207	Target Neighborhood Hits	71	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN9_HUMAN
θ value	θ > 10 (rank : 729)	NC score	0.122184 (rank : 379)
Query Neighborhood Hits	207	Target Neighborhood Hits	79	Shared Neighborhood Hits	15
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
θ value	θ > 10 (rank : 730)	NC score	0.122597 (rank : 378)
Query Neighborhood Hits	207	Target Neighborhood Hits	78	Shared Neighborhood Hits	15
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPR2_HUMAN
θ value	θ > 10 (rank : 731)	NC score	0.119590 (rank : 390)
Query Neighborhood Hits	207	Target Neighborhood Hits	103	Shared Neighborhood Hits	15
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPR2_MOUSE
θ value	θ > 10 (rank : 732)	NC score	0.119754 (rank : 389)
Query Neighborhood Hits	207	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRA_HUMAN
θ value	θ > 10 (rank : 733)	NC score	0.152886 (rank : 334)
Query Neighborhood Hits	207	Target Neighborhood Hits	101	Shared Neighborhood Hits	16
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
θ value	θ > 10 (rank : 734)	NC score	0.152486 (rank : 336)
Query Neighborhood Hits	207	Target Neighborhood Hits	93	Shared Neighborhood Hits	15
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRE_HUMAN
θ value	θ > 10 (rank : 735)	NC score	0.152998 (rank : 333)
Query Neighborhood Hits	207	Target Neighborhood Hits	92	Shared Neighborhood Hits	15
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
θ value	θ > 10 (rank : 736)	NC score	0.153390 (rank : 331)
Query Neighborhood Hits	207	Target Neighborhood Hits	86	Shared Neighborhood Hits	15
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRG_HUMAN
θ value	θ > 10 (rank : 737)	NC score	0.156818 (rank : 325)
Query Neighborhood Hits	207	Target Neighborhood Hits	231	Shared Neighborhood Hits	54
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
θ value	θ > 10 (rank : 738)	NC score	0.154987 (rank : 328)
Query Neighborhood Hits	207	Target Neighborhood Hits	260	Shared Neighborhood Hits	52
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRN_HUMAN
θ value	θ > 10 (rank : 739)	NC score	0.120149 (rank : 386)
Query Neighborhood Hits	207	Target Neighborhood Hits	156	Shared Neighborhood Hits	17
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
θ value	θ > 10 (rank : 740)	NC score	0.119796 (rank : 388)
Query Neighborhood Hits	207	Target Neighborhood Hits	240	Shared Neighborhood Hits	22
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRO_HUMAN
θ value	θ > 10 (rank : 741)	NC score	0.208955 (rank : 251)
Query Neighborhood Hits	207	Target Neighborhood Hits	139	Shared Neighborhood Hits	58
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRR_HUMAN
θ value	θ > 10 (rank : 742)	NC score	0.119136 (rank : 394)
Query Neighborhood Hits	207	Target Neighborhood Hits	77	Shared Neighborhood Hits	15
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTPRR_MOUSE
θ value	θ > 10 (rank : 743)	NC score	0.119278 (rank : 392)
Query Neighborhood Hits	207	Target Neighborhood Hits	84	Shared Neighborhood Hits	16
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRV_MOUSE
θ value	θ > 10 (rank : 744)	NC score	0.260673 (rank : 189)
Query Neighborhood Hits	207	Target Neighborhood Hits	179	Shared Neighborhood Hits	75
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTPRZ_HUMAN
θ value	θ > 10 (rank : 745)	NC score	0.152415 (rank : 337)
Query Neighborhood Hits	207	Target Neighborhood Hits	255	Shared Neighborhood Hits	40
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PVRL1_HUMAN
θ value	θ > 10 (rank : 746)	NC score	0.106056 (rank : 420)
Query Neighborhood Hits	207	Target Neighborhood Hits	219	Shared Neighborhood Hits	43
SwissProt Accessions	Q15223, O75465, Q9HBE6, Q9HBW2	Gene names	PVRL1, HVEC, PRR1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (Herpesvirus Ig-like receptor) (HIgR) (CD111 antigen).

PVRL1_MOUSE
θ value	θ > 10 (rank : 747)	NC score	0.099866 (rank : 441)
Query Neighborhood Hits	207	Target Neighborhood Hits	201	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JKF6, Q9ERL5, Q9JI17	Gene names	Pvrl1, Hvec, Prr1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (CD111 antigen).

PVRL2_HUMAN
θ value	θ > 10 (rank : 748)	NC score	0.072070 (rank : 607)
Query Neighborhood Hits	207	Target Neighborhood Hits	185	Shared Neighborhood Hits	33
SwissProt Accessions	Q92692, O75455, Q96J29	Gene names	PVRL2, HVEB, PRR2
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Herpes virus entry mediator B) (HveB) (Nectin-2) (CD112 antigen).

PVRL2_MOUSE
θ value	θ > 10 (rank : 749)	NC score	0.082604 (rank : 547)
Query Neighborhood Hits	207	Target Neighborhood Hits	242	Shared Neighborhood Hits	36
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

PVRL3_HUMAN
θ value	θ > 10 (rank : 750)	NC score	0.107722 (rank : 414)
Query Neighborhood Hits	207	Target Neighborhood Hits	204	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NQS3, Q6NVZ3, Q8WVU4, Q9BVA9, Q9Y412	Gene names	PVRL3, PRR3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Nectin-3) (CDw113 antigen).

PVRL3_MOUSE
θ value	θ > 10 (rank : 751)	NC score	0.118529 (rank : 397)
Query Neighborhood Hits	207	Target Neighborhood Hits	212	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JLB9, Q9D006, Q9JLB7, Q9JLB8	Gene names	Pvrl3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Cell adhesion molecule nectin-3) (Nectin-3) (CDw113 antigen).

PVR_HUMAN
θ value	θ > 10 (rank : 752)	NC score	0.092289 (rank : 483)
Query Neighborhood Hits	207	Target Neighborhood Hits	195	Shared Neighborhood Hits	41
SwissProt Accessions	P15151, P15152, Q15267, Q15268, Q96BJ1	Gene names	PVR, PVS
Domain Architecture
Description	Poliovirus receptor precursor (Nectin-like protein 5) (Necl-5) (CD155 antigen).

RAF1_HUMAN
θ value	θ > 10 (rank : 753)	NC score	0.077497 (rank : 574)
Query Neighborhood Hits	207	Target Neighborhood Hits	886	Shared Neighborhood Hits	50
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAF1_MOUSE
θ value	θ > 10 (rank : 754)	NC score	0.077918 (rank : 570)
Query Neighborhood Hits	207	Target Neighborhood Hits	886	Shared Neighborhood Hits	51
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAGE_HUMAN
θ value	θ > 10 (rank : 755)	NC score	0.311236 (rank : 145)
Query Neighborhood Hits	207	Target Neighborhood Hits	269	Shared Neighborhood Hits	78
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

RAGE_MOUSE
θ value	θ > 10 (rank : 756)	NC score	0.293851 (rank : 160)
Query Neighborhood Hits	207	Target Neighborhood Hits	295	Shared Neighborhood Hits	75
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

RET_HUMAN
θ value	θ > 10 (rank : 757)	NC score	0.095234 (rank : 467)
Query Neighborhood Hits	207	Target Neighborhood Hits	873	Shared Neighborhood Hits	49
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RET_MOUSE
θ value	θ > 10 (rank : 758)	NC score	0.095412 (rank : 466)
Query Neighborhood Hits	207	Target Neighborhood Hits	884	Shared Neighborhood Hits	52
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RIMB2_MOUSE
θ value	θ > 10 (rank : 759)	NC score	0.178130 (rank : 284)
Query Neighborhood Hits	207	Target Neighborhood Hits	246	Shared Neighborhood Hits	52
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

RIPK1_HUMAN
θ value	θ > 10 (rank : 760)	NC score	0.063954 (rank : 666)
Query Neighborhood Hits	207	Target Neighborhood Hits	891	Shared Neighborhood Hits	50
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RIPK1_MOUSE
θ value	θ > 10 (rank : 761)	NC score	0.063573 (rank : 671)
Query Neighborhood Hits	207	Target Neighborhood Hits	874	Shared Neighborhood Hits	50
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

RIPK2_HUMAN
θ value	θ > 10 (rank : 762)	NC score	0.069059 (rank : 632)
Query Neighborhood Hits	207	Target Neighborhood Hits	774	Shared Neighborhood Hits	48
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

RIPK2_MOUSE
θ value	θ > 10 (rank : 763)	NC score	0.071099 (rank : 619)
Query Neighborhood Hits	207	Target Neighborhood Hits	776	Shared Neighborhood Hits	49
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

RIPK3_HUMAN
θ value	θ > 10 (rank : 764)	NC score	0.072483 (rank : 605)
Query Neighborhood Hits	207	Target Neighborhood Hits	828	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).

RIPK3_MOUSE
θ value	θ > 10 (rank : 765)	NC score	0.060525 (rank : 705)
Query Neighborhood Hits	207	Target Neighborhood Hits	867	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

RIPK4_HUMAN
θ value	θ > 10 (rank : 766)	NC score	0.052881 (rank : 799)
Query Neighborhood Hits	207	Target Neighborhood Hits	1094	Shared Neighborhood Hits	52
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

RIPK5_HUMAN
θ value	θ > 10 (rank : 767)	NC score	0.052092 (rank : 814)
Query Neighborhood Hits	207	Target Neighborhood Hits	864	Shared Neighborhood Hits	50
SwissProt Accessions	Q6XUX3, O75060, Q5RKT0, Q6IN87, Q6P997, Q86Y03, Q9P1S5	Gene names	RIPK5, KIAA0472, RIP5
Domain Architecture	No domain graphic available
Description	Receptor-interacting serine/threonine-protein kinase 5 (EC 2.7.11.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase).

RIPK5_MOUSE
θ value	θ > 10 (rank : 768)	NC score	0.052283 (rank : 809)
Query Neighborhood Hits	207	Target Neighborhood Hits	874	Shared Neighborhood Hits	50
SwissProt Accessions	Q6XUX1, Q3ULK4, Q5EBN5, Q8C7D4, Q8C923, Q9CTP7	Gene names	Ripk5
Domain Architecture	No domain graphic available
Description	Receptor-interacting serine/threonine-protein kinase 5 (EC 2.7.11.1) (Dusty protein kinase) (Dusty PK).

ROBO4_HUMAN
θ value	θ > 10 (rank : 769)	NC score	0.448782 (rank : 75)
Query Neighborhood Hits	207	Target Neighborhood Hits	364	Shared Neighborhood Hits	103
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

ROBO4_MOUSE
θ value	θ > 10 (rank : 770)	NC score	0.449768 (rank : 74)
Query Neighborhood Hits	207	Target Neighborhood Hits	358	Shared Neighborhood Hits	101
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

RON_HUMAN
θ value	θ > 10 (rank : 771)	NC score	0.092869 (rank : 480)
Query Neighborhood Hits	207	Target Neighborhood Hits	842	Shared Neighborhood Hits	49
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

RON_MOUSE
θ value	θ > 10 (rank : 772)	NC score	0.094711 (rank : 469)
Query Neighborhood Hits	207	Target Neighborhood Hits	836	Shared Neighborhood Hits	49
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

ROR1_HUMAN
θ value	θ > 10 (rank : 773)	NC score	0.184026 (rank : 276)
Query Neighborhood Hits	207	Target Neighborhood Hits	1018	Shared Neighborhood Hits	116
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

ROR1_MOUSE
θ value	θ > 10 (rank : 774)	NC score	0.182642 (rank : 277)
Query Neighborhood Hits	207	Target Neighborhood Hits	1025	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

ROR2_HUMAN
θ value	θ > 10 (rank : 775)	NC score	0.190376 (rank : 270)
Query Neighborhood Hits	207	Target Neighborhood Hits	1014	Shared Neighborhood Hits	118
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

ROR2_MOUSE
θ value	θ > 10 (rank : 776)	NC score	0.195382 (rank : 268)
Query Neighborhood Hits	207	Target Neighborhood Hits	1000	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

RYK_HUMAN
θ value	θ > 10 (rank : 777)	NC score	0.109011 (rank : 409)
Query Neighborhood Hits	207	Target Neighborhood Hits	701	Shared Neighborhood Hits	47
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

RYK_MOUSE
θ value	θ > 10 (rank : 778)	NC score	0.107436 (rank : 415)
Query Neighborhood Hits	207	Target Neighborhood Hits	715	Shared Neighborhood Hits	47
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

SHPS1_HUMAN
θ value	θ > 10 (rank : 779)	NC score	0.077957 (rank : 569)
Query Neighborhood Hits	207	Target Neighborhood Hits	455	Shared Neighborhood Hits	44
SwissProt Accessions	P78324, O00683, O43799, Q8N517, Q8TAL8, Q9H0Z2, Q9UDX2, Q9UIJ6, Q9Y4U9	Gene names	SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type substrate 1 precursor (SHP substrate 1) (SHPS-1) (Inhibitory receptor SHPS-1) (Signal- regulatory protein alpha-1) (Sirp-alpha-1) (Sirp-alpha-2) (Sirp-alpha- 3) (MyD-1 antigen) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (Macrophage fusion receptor) (p84) (CD172a antigen).

SIG10_HUMAN
θ value	θ > 10 (rank : 780)	NC score	0.244411 (rank : 207)
Query Neighborhood Hits	207	Target Neighborhood Hits	363	Shared Neighborhood Hits	74
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

SIG11_HUMAN
θ value	θ > 10 (rank : 781)	NC score	0.249556 (rank : 201)
Query Neighborhood Hits	207	Target Neighborhood Hits	273	Shared Neighborhood Hits	75
SwissProt Accessions	Q96RL6	Gene names	SIGLEC11
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 11 precursor (Siglec-11) (Sialic acid-binding lectin 11).

SIG12_HUMAN
θ value	θ > 10 (rank : 782)	NC score	0.140184 (rank : 362)
Query Neighborhood Hits	207	Target Neighborhood Hits	245	Shared Neighborhood Hits	71
SwissProt Accessions	Q96PQ1, Q8IYH7	Gene names	SIGLEC12, SIGLECL1, SLG
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1).

SIG12_MOUSE
θ value	θ > 10 (rank : 783)	NC score	0.070089 (rank : 624)
Query Neighborhood Hits	207	Target Neighborhood Hits	225	Shared Neighborhood Hits	44
SwissProt Accessions	Q91Y57	Gene names	Siglec12, Siglec5, Siglece, Siglecl1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1) (Sialic acid-binding Ig-like lectin 5) (Siglec-5) (mSiglec-E) (Myeloid inhibitory siglec) (MIS).

SIGL5_HUMAN
θ value	θ > 10 (rank : 784)	NC score	0.150818 (rank : 343)
Query Neighborhood Hits	207	Target Neighborhood Hits	246	Shared Neighborhood Hits	66
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

SIGL5_MOUSE
θ value	θ > 10 (rank : 785)	NC score	0.196459 (rank : 266)
Query Neighborhood Hits	207	Target Neighborhood Hits	271	Shared Neighborhood Hits	67
SwissProt Accessions	Q920G3	Gene names	Siglec5, Siglecf
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Sialic acid-binding Ig-like lectin-F) (mSiglec-F).

SIGL6_HUMAN
θ value	θ > 10 (rank : 786)	NC score	0.127387 (rank : 373)
Query Neighborhood Hits	207	Target Neighborhood Hits	233	Shared Neighborhood Hits	67
SwissProt Accessions	O43699, O15388, O43700	Gene names	SIGLEC6, CD33L, CD33L1, OBBP1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 6 precursor (Siglec-6) (Obesity- binding protein 1) (OB-BP1) (CD33 antigen-like 1) (CDw327 antigen).

SIGL7_HUMAN
θ value	θ > 10 (rank : 787)	NC score	0.082157 (rank : 550)
Query Neighborhood Hits	207	Target Neighborhood Hits	180	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y286, Q9NZQ1, Q9UJ86, Q9UJ87, Q9Y502	Gene names	SIGLEC7, AIRM1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 7 precursor (Siglec-7) (QA79 membrane protein) (Adhesion inhibitory receptor molecule 1) (AIRM-1) (p75) (D-siglec) (CDw328 antigen).

SIGL8_HUMAN
θ value	θ > 10 (rank : 788)	NC score	0.152067 (rank : 338)
Query Neighborhood Hits	207	Target Neighborhood Hits	252	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NYZ4, Q7Z728	Gene names	SIGLEC8, SAF2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 8 precursor (Siglec-8) (Sialoadhesin family member 2) (SAF-2) (CDw329 antigen).

SIRB1_HUMAN
θ value	θ > 10 (rank : 789)	NC score	0.074109 (rank : 590)
Query Neighborhood Hits	207	Target Neighborhood Hits	422	Shared Neighborhood Hits	38
SwissProt Accessions	O00241, Q5TFR0, Q8TB12, Q9H1U5, Q9Y4V0	Gene names	SIRPB1
Domain Architecture
Description	Signal-regulatory protein beta-1 precursor (SIRP-beta-1) (CD172b antigen).

SN1L1_MOUSE
θ value	θ > 10 (rank : 790)	NC score	0.050549 (rank : 846)
Query Neighborhood Hits	207	Target Neighborhood Hits	895	Shared Neighborhood Hits	50
SwissProt Accessions	Q60670	Gene names	Snf1lk, Msk
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1- like kinase).

SN1L2_HUMAN
θ value	θ > 10 (rank : 791)	NC score	0.050447 (rank : 848)
Query Neighborhood Hits	207	Target Neighborhood Hits	964	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H0K1, O94878, Q6AZE2, Q76N03, Q8NCV7, Q96CZ8	Gene names	SNF1LK2, KIAA0781, QIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Qin- induced kinase).

SN1L2_MOUSE
θ value	θ > 10 (rank : 792)	NC score	0.050065 (rank : 858)
Query Neighborhood Hits	207	Target Neighborhood Hits	944	Shared Neighborhood Hits	51
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).

SN_HUMAN
θ value	θ > 10 (rank : 793)	NC score	0.304127 (rank : 150)
Query Neighborhood Hits	207	Target Neighborhood Hits	434	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

SN_MOUSE
θ value	θ > 10 (rank : 794)	NC score	0.313334 (rank : 139)
Query Neighborhood Hits	207	Target Neighborhood Hits	416	Shared Neighborhood Hits	85
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

SRC_HUMAN
θ value	θ > 10 (rank : 795)	NC score	0.088482 (rank : 520)
Query Neighborhood Hits	207	Target Neighborhood Hits	1058	Shared Neighborhood Hits	52
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

SRC_MOUSE
θ value	θ > 10 (rank : 796)	NC score	0.088822 (rank : 518)
Query Neighborhood Hits	207	Target Neighborhood Hits	1033	Shared Neighborhood Hits	52
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

SREC2_HUMAN
θ value	θ > 10 (rank : 797)	NC score	0.086423 (rank : 530)
Query Neighborhood Hits	207	Target Neighborhood Hits	645	Shared Neighborhood Hits	43
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	θ > 10 (rank : 798)	NC score	0.082600 (rank : 548)
Query Neighborhood Hits	207	Target Neighborhood Hits	605	Shared Neighborhood Hits	33
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC_HUMAN
θ value	θ > 10 (rank : 799)	NC score	0.086107 (rank : 531)
Query Neighborhood Hits	207	Target Neighborhood Hits	645	Shared Neighborhood Hits	39
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

SRMS_HUMAN
θ value	θ > 10 (rank : 800)	NC score	0.093689 (rank : 477)
Query Neighborhood Hits	207	Target Neighborhood Hits	946	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

SRMS_MOUSE
θ value	θ > 10 (rank : 801)	NC score	0.092230 (rank : 484)
Query Neighborhood Hits	207	Target Neighborhood Hits	964	Shared Neighborhood Hits	51
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

ST17A_HUMAN
θ value	θ > 10 (rank : 802)	NC score	0.052066 (rank : 815)
Query Neighborhood Hits	207	Target Neighborhood Hits	843	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UEE5, Q8IVC8	Gene names	STK17A, DRAK1
Domain Architecture
Description	Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1).

ST17B_HUMAN
θ value	θ > 10 (rank : 803)	NC score	0.053406 (rank : 790)
Query Neighborhood Hits	207	Target Neighborhood Hits	833	Shared Neighborhood Hits	46
SwissProt Accessions	O94768	Gene names	STK17B, DRAK2
Domain Architecture
Description	Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2).

ST17B_MOUSE
θ value	θ > 10 (rank : 804)	NC score	0.056264 (rank : 750)
Query Neighborhood Hits	207	Target Neighborhood Hits	838	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BG48, Q3TNG7, Q8BLV9, Q923E7	Gene names	Stk17b, Drak2
Domain Architecture
Description	Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2).

STAB1_HUMAN
θ value	θ > 10 (rank : 805)	NC score	0.060339 (rank : 707)
Query Neighborhood Hits	207	Target Neighborhood Hits	546	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
θ value	θ > 10 (rank : 806)	NC score	0.062133 (rank : 687)
Query Neighborhood Hits	207	Target Neighborhood Hits	566	Shared Neighborhood Hits	40
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_HUMAN
θ value	θ > 10 (rank : 807)	NC score	0.055443 (rank : 764)
Query Neighborhood Hits	207	Target Neighborhood Hits	534	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB2_MOUSE
θ value	θ > 10 (rank : 808)	NC score	0.061066 (rank : 700)
Query Neighborhood Hits	207	Target Neighborhood Hits	528	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

STK16_HUMAN
θ value	θ > 10 (rank : 809)	NC score	0.059895 (rank : 712)
Query Neighborhood Hits	207	Target Neighborhood Hits	824	Shared Neighborhood Hits	50
SwissProt Accessions	O75716, Q96KI2, Q9UEN3, Q9UP78	Gene names	STK16, MPSK1, PKL12, TSF1
Domain Architecture
Description	Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Protein kinase PKL12) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (TGF-beta-stimulated factor 1) (TSF-1) (hPSK).

STK16_MOUSE
θ value	θ > 10 (rank : 810)	NC score	0.059146 (rank : 718)
Query Neighborhood Hits	207	Target Neighborhood Hits	824	Shared Neighborhood Hits	50
SwissProt Accessions	O88697, Q9JMJ0, Q9JMJ1, Q9QX00	Gene names	Stk16, Edpk, Krct, Mpsk1, Pkl12, Tsf1
Domain Architecture
Description	Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Protein kinase PKL12) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (TGF-beta-stimulated factor 1) (TSF-1) (Protein kinase Krct).

STK24_HUMAN
θ value	θ > 10 (rank : 811)	NC score	0.056052 (rank : 753)
Query Neighborhood Hits	207	Target Neighborhood Hits	853	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y6E0, O14840	Gene names	STK24, MST3, STK3
Domain Architecture
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1) (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3).

STK24_MOUSE
θ value	θ > 10 (rank : 812)	NC score	0.056488 (rank : 746)
Query Neighborhood Hits	207	Target Neighborhood Hits	856	Shared Neighborhood Hits	50
SwissProt Accessions	Q99KH8	Gene names	Stk24
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1).

STK25_HUMAN
θ value	θ > 10 (rank : 813)	NC score	0.053506 (rank : 789)
Query Neighborhood Hits	207	Target Neighborhood Hits	853	Shared Neighborhood Hits	50
SwissProt Accessions	O00506, Q15522, Q5BJF1	Gene names	STK25, SOK1, YSK1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

STK25_MOUSE
θ value	θ > 10 (rank : 814)	NC score	0.053516 (rank : 788)
Query Neighborhood Hits	207	Target Neighborhood Hits	851	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z2W1	Gene names	Stk25, Sok1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

STK33_HUMAN
θ value	θ > 10 (rank : 815)	NC score	0.055963 (rank : 755)
Query Neighborhood Hits	207	Target Neighborhood Hits	879	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BYT3, Q658S6, Q8NEF5	Gene names	STK33
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 33 (EC 2.7.11.1).

STK36_HUMAN
θ value	θ > 10 (rank : 816)	NC score	0.050856 (rank : 836)
Query Neighborhood Hits	207	Target Neighborhood Hits	896	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2	Gene names	STK36, KIAA1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

STK36_MOUSE
θ value	θ > 10 (rank : 817)	NC score	0.052211 (rank : 810)
Query Neighborhood Hits	207	Target Neighborhood Hits	877	Shared Neighborhood Hits	50
SwissProt Accessions	Q69ZM6, Q6PDI0, Q80XQ6	Gene names	Stk36, Kiaa1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

STK39_MOUSE
θ value	θ > 10 (rank : 818)	NC score	0.050020 (rank : 860)
Query Neighborhood Hits	207	Target Neighborhood Hits	915	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

STK3_HUMAN
θ value	θ > 10 (rank : 819)	NC score	0.054518 (rank : 779)
Query Neighborhood Hits	207	Target Neighborhood Hits	861	Shared Neighborhood Hits	50
SwissProt Accessions	Q13188, Q15445, Q15801, Q96FM6	Gene names	STK3, MST2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1).

STK3_MOUSE
θ value	θ > 10 (rank : 820)	NC score	0.054959 (rank : 770)
Query Neighborhood Hits	207	Target Neighborhood Hits	869	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JI10, Q60877, Q80UG4, Q8CI58	Gene names	Stk3, Mess1, Mst2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2).

STK4_HUMAN
θ value	θ > 10 (rank : 821)	NC score	0.055374 (rank : 765)
Query Neighborhood Hits	207	Target Neighborhood Hits	870	Shared Neighborhood Hits	50
SwissProt Accessions	Q13043, Q15802, Q4G156, Q5H982, Q6PD60, Q9BR32, Q9NTZ4	Gene names	STK4, MST1
Domain Architecture
Description	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2).

STK4_MOUSE
θ value	θ > 10 (rank : 822)	NC score	0.055606 (rank : 761)
Query Neighborhood Hits	207	Target Neighborhood Hits	873	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JI11	Gene names	Stk4, Mst1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1).

STYK1_HUMAN
θ value	θ > 10 (rank : 823)	NC score	0.098511 (rank : 448)
Query Neighborhood Hits	207	Target Neighborhood Hits	786	Shared Neighborhood Hits	50
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

STYK1_MOUSE
θ value	θ > 10 (rank : 824)	NC score	0.101085 (rank : 433)
Query Neighborhood Hits	207	Target Neighborhood Hits	779	Shared Neighborhood Hits	51
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

TEC_HUMAN
θ value	θ > 10 (rank : 825)	NC score	0.090117 (rank : 501)
Query Neighborhood Hits	207	Target Neighborhood Hits	1006	Shared Neighborhood Hits	51
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TEC_MOUSE
θ value	θ > 10 (rank : 826)	NC score	0.089988 (rank : 503)
Query Neighborhood Hits	207	Target Neighborhood Hits	1006	Shared Neighborhood Hits	51
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

TESK1_HUMAN
θ value	θ > 10 (rank : 827)	NC score	0.068084 (rank : 638)
Query Neighborhood Hits	207	Target Neighborhood Hits	864	Shared Neighborhood Hits	50
SwissProt Accessions	Q15569	Gene names	TESK1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

TESK1_MOUSE
θ value	θ > 10 (rank : 828)	NC score	0.069263 (rank : 630)
Query Neighborhood Hits	207	Target Neighborhood Hits	862	Shared Neighborhood Hits	51
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

TESK2_HUMAN
θ value	θ > 10 (rank : 829)	NC score	0.071194 (rank : 618)
Query Neighborhood Hits	207	Target Neighborhood Hits	851	Shared Neighborhood Hits	50
SwissProt Accessions	Q96S53, Q8N520, Q9Y3Q6	Gene names	TESK2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

TESK2_MOUSE
θ value	θ > 10 (rank : 830)	NC score	0.071212 (rank : 617)
Query Neighborhood Hits	207	Target Neighborhood Hits	833	Shared Neighborhood Hits	50
SwissProt Accessions	Q8VCT9	Gene names	Tesk2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

TEX14_HUMAN
θ value	θ > 10 (rank : 831)	NC score	0.071834 (rank : 612)
Query Neighborhood Hits	207	Target Neighborhood Hits	1103	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TEX14_MOUSE
θ value	θ > 10 (rank : 832)	NC score	0.064086 (rank : 665)
Query Neighborhood Hits	207	Target Neighborhood Hits	1333	Shared Neighborhood Hits	50
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

TGFR1_HUMAN
θ value	θ > 10 (rank : 833)	NC score	0.057801 (rank : 735)
Query Neighborhood Hits	207	Target Neighborhood Hits	755	Shared Neighborhood Hits	49
SwissProt Accessions	P36897	Gene names	TGFBR1
Domain Architecture
Description	TGF-beta receptor type-1 precursor (EC 2.7.11.30) (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (Serine/threonine-protein kinase receptor R4) (SKR4) (Activin receptor-like kinase 5) (ALK-5).

TGFR1_MOUSE
θ value	θ > 10 (rank : 834)	NC score	0.058032 (rank : 732)
Query Neighborhood Hits	207	Target Neighborhood Hits	753	Shared Neighborhood Hits	49
SwissProt Accessions	Q64729	Gene names	Tgfbr1
Domain Architecture
Description	TGF-beta receptor type-1 precursor (EC 2.7.11.30) (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (ESK2).

TGFR2_HUMAN
θ value	θ > 10 (rank : 835)	NC score	0.059059 (rank : 721)
Query Neighborhood Hits	207	Target Neighborhood Hits	748	Shared Neighborhood Hits	48
SwissProt Accessions	P37173, Q15580, Q6DKT6, Q99474	Gene names	TGFBR2
Domain Architecture
Description	TGF-beta receptor type-2 precursor (EC 2.7.11.30) (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor).

TGFR2_MOUSE
θ value	θ > 10 (rank : 836)	NC score	0.059389 (rank : 716)
Query Neighborhood Hits	207	Target Neighborhood Hits	748	Shared Neighborhood Hits	49
SwissProt Accessions	Q62312, Q63947	Gene names	Tgfbr2
Domain Architecture
Description	TGF-beta receptor type-2 precursor (EC 2.7.11.30) (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor).

TMIGD_HUMAN
θ value	θ > 10 (rank : 837)	NC score	0.329880 (rank : 120)
Query Neighborhood Hits	207	Target Neighborhood Hits	240	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

TMIGD_MOUSE
θ value	θ > 10 (rank : 838)	NC score	0.319352 (rank : 133)
Query Neighborhood Hits	207	Target Neighborhood Hits	234	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

TNI3K_HUMAN
θ value	θ > 10 (rank : 839)	NC score	0.062532 (rank : 680)
Query Neighborhood Hits	207	Target Neighborhood Hits	1084	Shared Neighborhood Hits	50
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

TNI3K_MOUSE
θ value	θ > 10 (rank : 840)	NC score	0.063246 (rank : 672)
Query Neighborhood Hits	207	Target Neighborhood Hits	1079	Shared Neighborhood Hits	51
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

TNK1_HUMAN
θ value	θ > 10 (rank : 841)	NC score	0.101572 (rank : 431)
Query Neighborhood Hits	207	Target Neighborhood Hits	815	Shared Neighborhood Hits	50
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

TNK1_MOUSE
θ value	θ > 10 (rank : 842)	NC score	0.099724 (rank : 443)
Query Neighborhood Hits	207	Target Neighborhood Hits	806	Shared Neighborhood Hits	53
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

TOPK_HUMAN
θ value	θ > 10 (rank : 843)	NC score	0.062488 (rank : 681)
Query Neighborhood Hits	207	Target Neighborhood Hits	605	Shared Neighborhood Hits	44
SwissProt Accessions	Q96KB5, Q9NPD9, Q9NYL7, Q9NZK6	Gene names	PBK, TOPK
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (MAPKK-like protein kinase) (Nori-3).

TOPK_MOUSE
θ value	θ > 10 (rank : 844)	NC score	0.061914 (rank : 690)
Query Neighborhood Hits	207	Target Neighborhood Hits	618	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JJ78, Q922V2, Q9D184	Gene names	Pbk, Topk
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase).

TPSNR_MOUSE
θ value	θ > 10 (rank : 845)	NC score	0.066235 (rank : 647)
Query Neighborhood Hits	207	Target Neighborhood Hits	336	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VD31	Gene names	Tapbpl
Domain Architecture	No domain graphic available
Description	Tapasin-related protein precursor (TAPASIN-R) (Tapasin-like) (TAP- binding protein-related protein) (TAPBP-R) (TAP-binding protein-like).

TRI18_HUMAN
θ value	θ > 10 (rank : 846)	NC score	0.056098 (rank : 751)
Query Neighborhood Hits	207	Target Neighborhood Hits	307	Shared Neighborhood Hits	42
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

TRI36_MOUSE
θ value	θ > 10 (rank : 847)	NC score	0.050161 (rank : 855)
Query Neighborhood Hits	207	Target Neighborhood Hits	266	Shared Neighborhood Hits	33
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

TRIO_HUMAN
θ value	θ > 10 (rank : 848)	NC score	0.120024 (rank : 387)
Query Neighborhood Hits	207	Target Neighborhood Hits	1580	Shared Neighborhood Hits	114
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

TXK_HUMAN
θ value	θ > 10 (rank : 849)	NC score	0.091610 (rank : 487)
Query Neighborhood Hits	207	Target Neighborhood Hits	971	Shared Neighborhood Hits	50
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

TXK_MOUSE
θ value	θ > 10 (rank : 850)	NC score	0.092165 (rank : 485)
Query Neighborhood Hits	207	Target Neighborhood Hits	980	Shared Neighborhood Hits	50
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

TYK2_HUMAN
θ value	θ > 10 (rank : 851)	NC score	0.082064 (rank : 552)
Query Neighborhood Hits	207	Target Neighborhood Hits	841	Shared Neighborhood Hits	50
SwissProt Accessions	P29597, Q6QB10, Q96CH0	Gene names	TYK2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

TYK2_MOUSE
θ value	θ > 10 (rank : 852)	NC score	0.082681 (rank : 546)
Query Neighborhood Hits	207	Target Neighborhood Hits	850	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

ULK1_HUMAN
θ value	θ > 10 (rank : 853)	NC score	0.053007 (rank : 797)
Query Neighborhood Hits	207	Target Neighborhood Hits	1121	Shared Neighborhood Hits	54
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

ULK1_MOUSE
θ value	θ > 10 (rank : 854)	NC score	0.052884 (rank : 798)
Query Neighborhood Hits	207	Target Neighborhood Hits	1214	Shared Neighborhood Hits	56
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

ULK2_HUMAN
θ value	θ > 10 (rank : 855)	NC score	0.052297 (rank : 808)
Query Neighborhood Hits	207	Target Neighborhood Hits	979	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

ULK2_MOUSE
θ value	θ > 10 (rank : 856)	NC score	0.051825 (rank : 819)
Query Neighborhood Hits	207	Target Neighborhood Hits	943	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).

ULK3_HUMAN
θ value	θ > 10 (rank : 857)	NC score	0.050139 (rank : 856)
Query Neighborhood Hits	207	Target Neighborhood Hits	830	Shared Neighborhood Hits	50
SwissProt Accessions	Q6PHR2, Q9NPN5, Q9UFS4	Gene names	ULK3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3).

ULK3_MOUSE
θ value	θ > 10 (rank : 858)	NC score	0.050738 (rank : 841)
Query Neighborhood Hits	207	Target Neighborhood Hits	872	Shared Neighborhood Hits	50
SwissProt Accessions	Q3U3Q1, Q8K1X6, Q9DBR8	Gene names	Ulk3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3).

UNC5A_HUMAN
θ value	θ > 10 (rank : 859)	NC score	0.160568 (rank : 315)
Query Neighborhood Hits	207	Target Neighborhood Hits	198	Shared Neighborhood Hits	64
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5A_MOUSE
θ value	θ > 10 (rank : 860)	NC score	0.138685 (rank : 363)
Query Neighborhood Hits	207	Target Neighborhood Hits	203	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

UNC5B_HUMAN
θ value	θ > 10 (rank : 861)	NC score	0.142442 (rank : 357)
Query Neighborhood Hits	207	Target Neighborhood Hits	225	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
θ value	θ > 10 (rank : 862)	NC score	0.141223 (rank : 358)
Query Neighborhood Hits	207	Target Neighborhood Hits	226	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

UNC5C_HUMAN
θ value	θ > 10 (rank : 863)	NC score	0.148483 (rank : 351)
Query Neighborhood Hits	207	Target Neighborhood Hits	226	Shared Neighborhood Hits	66
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

UNC5C_MOUSE
θ value	θ > 10 (rank : 864)	NC score	0.149192 (rank : 349)
Query Neighborhood Hits	207	Target Neighborhood Hits	225	Shared Neighborhood Hits	67
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

UNC5D_HUMAN
θ value	θ > 10 (rank : 865)	NC score	0.169754 (rank : 300)
Query Neighborhood Hits	207	Target Neighborhood Hits	267	Shared Neighborhood Hits	73
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

UNC5D_MOUSE
θ value	θ > 10 (rank : 866)	NC score	0.175043 (rank : 290)
Query Neighborhood Hits	207	Target Neighborhood Hits	268	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

VCAM1_HUMAN
θ value	θ > 10 (rank : 867)	NC score	0.323103 (rank : 128)
Query Neighborhood Hits	207	Target Neighborhood Hits	352	Shared Neighborhood Hits	77
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

VCAM1_MOUSE
θ value	θ > 10 (rank : 868)	NC score	0.324986 (rank : 125)
Query Neighborhood Hits	207	Target Neighborhood Hits	320	Shared Neighborhood Hits	76
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

VGFR1_HUMAN
θ value	θ > 10 (rank : 869)	NC score	0.232945 (rank : 220)
Query Neighborhood Hits	207	Target Neighborhood Hits	1109	Shared Neighborhood Hits	116
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

VGFR1_MOUSE
θ value	θ > 10 (rank : 870)	NC score	0.230726 (rank : 225)
Query Neighborhood Hits	207	Target Neighborhood Hits	1118	Shared Neighborhood Hits	117
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

VGFR2_HUMAN
θ value	θ > 10 (rank : 871)	NC score	0.220830 (rank : 234)
Query Neighborhood Hits	207	Target Neighborhood Hits	1103	Shared Neighborhood Hits	116
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

VGFR2_MOUSE
θ value	θ > 10 (rank : 872)	NC score	0.219741 (rank : 238)
Query Neighborhood Hits	207	Target Neighborhood Hits	1089	Shared Neighborhood Hits	116
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

VGFR3_HUMAN
θ value	θ > 10 (rank : 873)	NC score	0.188079 (rank : 271)
Query Neighborhood Hits	207	Target Neighborhood Hits	1037	Shared Neighborhood Hits	116
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

VGFR3_MOUSE
θ value	θ > 10 (rank : 874)	NC score	0.186428 (rank : 275)
Query Neighborhood Hits	207	Target Neighborhood Hits	1056	Shared Neighborhood Hits	117
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

VITRN_HUMAN
θ value	θ > 10 (rank : 875)	NC score	0.057026 (rank : 740)
Query Neighborhood Hits	207	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q6UXI7, Q6P7T3, Q96DT1	Gene names	VIT
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

VITRN_MOUSE
θ value	θ > 10 (rank : 876)	NC score	0.056985 (rank : 742)
Query Neighborhood Hits	207	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VHI5, Q3TZ47, Q8BQ41, Q8K047, Q9CYZ1	Gene names	Vit
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

VSIG2_HUMAN
θ value	θ > 10 (rank : 877)	NC score	0.261605 (rank : 188)
Query Neighborhood Hits	207	Target Neighborhood Hits	321	Shared Neighborhood Hits	74
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

VSIG2_MOUSE
θ value	θ > 10 (rank : 878)	NC score	0.248512 (rank : 203)
Query Neighborhood Hits	207	Target Neighborhood Hits	316	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

VSIG4_HUMAN
θ value	θ > 10 (rank : 879)	NC score	0.220224 (rank : 236)
Query Neighborhood Hits	207	Target Neighborhood Hits	236	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y279, Q6UXI4	Gene names	VSIG4, Z39IG
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 4 precursor (Protein Z39Ig).

VWF_HUMAN
θ value	θ > 10 (rank : 880)	NC score	0.052170 (rank : 812)
Query Neighborhood Hits	207	Target Neighborhood Hits	396	Shared Neighborhood Hits	30
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WEE1B_MOUSE
θ value	θ > 10 (rank : 881)	NC score	0.050254 (rank : 854)
Query Neighborhood Hits	207	Target Neighborhood Hits	765	Shared Neighborhood Hits	43
SwissProt Accessions	Q66JT0, Q4U4S4, Q7TPV9	Gene names	Wee1b, Wee2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase) (mWee1B).

WIF1_HUMAN
θ value	θ > 10 (rank : 882)	NC score	0.076796 (rank : 580)
Query Neighborhood Hits	207	Target Neighborhood Hits	392	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 883)	NC score	0.074973 (rank : 585)
Query Neighborhood Hits	207	Target Neighborhood Hits	393	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

YES_HUMAN
θ value	θ > 10 (rank : 884)	NC score	0.089733 (rank : 507)
Query Neighborhood Hits	207	Target Neighborhood Hits	1059	Shared Neighborhood Hits	53
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YES_MOUSE
θ value	θ > 10 (rank : 885)	NC score	0.089558 (rank : 510)
Query Neighborhood Hits	207	Target Neighborhood Hits	1052	Shared Neighborhood Hits	52
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

YSK4_HUMAN
θ value	θ > 10 (rank : 886)	NC score	0.053540 (rank : 787)
Query Neighborhood Hits	207	Target Neighborhood Hits	921	Shared Neighborhood Hits	51
SwissProt Accessions	Q56UN5, Q56UN1, Q56UN2, Q56UN3, Q56UN4, Q8N4E9, Q9H5T2	Gene names	YSK4, RCK
Domain Architecture	No domain graphic available
Description	SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1) (Regulated in COPD, protein kinase).

ZAP70_HUMAN
θ value	θ > 10 (rank : 887)	NC score	0.098979 (rank : 444)
Query Neighborhood Hits	207	Target Neighborhood Hits	893	Shared Neighborhood Hits	50
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ZAP70_MOUSE
θ value	θ > 10 (rank : 888)	NC score	0.098895 (rank : 446)
Query Neighborhood Hits	207	Target Neighborhood Hits	905	Shared Neighborhood Hits	50
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

Hits sorted by NC score

FNDC3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	207	Target Neighborhood Hits	207	Shared Neighborhood Hits	207
SwissProt Accessions	Q8BX90, Q2VEY7, Q6ZQ15, Q811D3, Q8BTM3	Gene names	Fndc3a, D14Ertd453e, Fndc3, Kiaa0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

FNDC3_HUMAN
NC score	0.993146 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	207	Target Neighborhood Hits	196	Shared Neighborhood Hits	178
SwissProt Accessions	Q9Y2H6, Q5JVF9, Q6EVH3, Q6N020, Q6P9D5, Q9H1W1	Gene names	FNDC3A, FNDC3, KIAA0970
Domain Architecture	No domain graphic available
Description	Fibronectin type-III domain-containing protein 3a.

SDK2_MOUSE
NC score	0.731309 (rank : 3)	θ value	1.2049e-28 (rank : 7)
Query Neighborhood Hits	207	Target Neighborhood Hits	480	Shared Neighborhood Hits	172
SwissProt Accessions	Q6V4S5, Q3TTK1, Q5U5W7, Q6ZPP2	Gene names	Sdk2, Kiaa1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK1_MOUSE
NC score	0.729848 (rank : 4)	θ value	5.40856e-29 (rank : 6)
Query Neighborhood Hits	207	Target Neighborhood Hits	495	Shared Neighborhood Hits	177
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

MYOM1_HUMAN
NC score	0.729755 (rank : 5)	θ value	3.75424e-22 (rank : 14)
Query Neighborhood Hits	207	Target Neighborhood Hits	405	Shared Neighborhood Hits	157
SwissProt Accessions	P52179	Gene names	MYOM1
Domain Architecture
Description	Myomesin-1 (190 kDa titin-associated protein) (190 kDa connectin- associated protein).

SDK2_HUMAN
NC score	0.727533 (rank : 6)	θ value	5.97985e-28 (rank : 9)
Query Neighborhood Hits	207	Target Neighborhood Hits	495	Shared Neighborhood Hits	176
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SDK1_HUMAN
NC score	0.723527 (rank : 7)	θ value	1.80048e-24 (rank : 12)
Query Neighborhood Hits	207	Target Neighborhood Hits	511	Shared Neighborhood Hits	173
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

NEO1_MOUSE
NC score	0.718727 (rank : 8)	θ value	1.09232e-21 (rank : 16)
Query Neighborhood Hits	207	Target Neighborhood Hits	523	Shared Neighborhood Hits	171
SwissProt Accessions	P97798	Gene names	Neo1, Ngn
Domain Architecture
Description	Neogenin precursor.

NEO1_HUMAN
NC score	0.717367 (rank : 9)	θ value	1.09232e-21 (rank : 15)
Query Neighborhood Hits	207	Target Neighborhood Hits	530	Shared Neighborhood Hits	169
SwissProt Accessions	Q92859, O00340	Gene names	NEO1, NGN
Domain Architecture
Description	Neogenin precursor.

MYOM1_MOUSE
NC score	0.695796 (rank : 10)	θ value	9.90251e-15 (rank : 23)
Query Neighborhood Hits	207	Target Neighborhood Hits	415	Shared Neighborhood Hits	168
SwissProt Accessions	Q62234	Gene names	Myom1
Domain Architecture
Description	Myomesin-1 (Skelemin).

MYOM2_HUMAN
NC score	0.694947 (rank : 11)	θ value	9.56915e-18 (rank : 19)
Query Neighborhood Hits	207	Target Neighborhood Hits	341	Shared Neighborhood Hits	148
SwissProt Accessions	P54296	Gene names	MYOM2
Domain Architecture
Description	Myomesin-2 (M-protein) (165 kDa titin-associated protein) (165 kDa connectin-associated protein).

DCC_HUMAN
NC score	0.692099 (rank : 12)	θ value	3.07829e-16 (rank : 20)
Query Neighborhood Hits	207	Target Neighborhood Hits	583	Shared Neighborhood Hits	170
SwissProt Accessions	P43146	Gene names	DCC
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC) (Colorectal cancer suppressor).

FINC_MOUSE
NC score	0.677166 (rank : 13)	θ value	1.68911e-14 (rank : 24)
Query Neighborhood Hits	207	Target Neighborhood Hits	309	Shared Neighborhood Hits	155
SwissProt Accessions	P11276, Q61567, Q61568, Q61569, Q64233, Q80UI4	Gene names	Fn1
Domain Architecture
Description	Fibronectin precursor (FN).

DCC_MOUSE
NC score	0.672983 (rank : 14)	θ value	8.95645e-16 (rank : 21)
Query Neighborhood Hits	207	Target Neighborhood Hits	896	Shared Neighborhood Hits	173
SwissProt Accessions	P70211	Gene names	Dcc
Domain Architecture
Description	Netrin receptor DCC precursor (Tumor suppressor protein DCC).

DSCL1_HUMAN
NC score	0.672560 (rank : 15)	θ value	2.69047e-20 (rank : 17)
Query Neighborhood Hits	207	Target Neighborhood Hits	589	Shared Neighborhood Hits	163
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

FINC_HUMAN
NC score	0.666176 (rank : 16)	θ value	1.74796e-11 (rank : 33)
Query Neighborhood Hits	207	Target Neighborhood Hits	302	Shared Neighborhood Hits	162
SwissProt Accessions	P02751, O95609, O95610, Q14312, Q14325, Q14326, Q6LDP6, Q86T27, Q8IVI8, Q96KP7, Q96KP8, Q96KP9, Q9H1B8, Q9HAP3, Q9UMK2	Gene names	FN1, FN
Domain Architecture
Description	Fibronectin precursor (FN) (Cold-insoluble globulin) (CIG).

NRCAM_HUMAN
NC score	0.661786 (rank : 17)	θ value	1.2105e-12 (rank : 26)
Query Neighborhood Hits	207	Target Neighborhood Hits	439	Shared Neighborhood Hits	160
SwissProt Accessions	Q92823, O15051, O15179, Q9UHI3, Q9UHI4	Gene names	NRCAM, KIAA0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (hBravo).

DSCAM_HUMAN
NC score	0.653714 (rank : 18)	θ value	1.74796e-11 (rank : 32)
Query Neighborhood Hits	207	Target Neighborhood Hits	524	Shared Neighborhood Hits	159
SwissProt Accessions	O60469, O60468	Gene names	DSCAM
Domain Architecture
Description	Down syndrome cell adhesion molecule precursor (CHD2).

L1CAM_HUMAN
NC score	0.652551 (rank : 19)	θ value	4.59992e-12 (rank : 28)
Query Neighborhood Hits	207	Target Neighborhood Hits	457	Shared Neighborhood Hits	166
SwissProt Accessions	P32004, Q8TA87	Gene names	L1CAM, CAML1, MIC5
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

NRCAM_MOUSE
NC score	0.650225 (rank : 20)	θ value	8.67504e-11 (rank : 35)
Query Neighborhood Hits	207	Target Neighborhood Hits	432	Shared Neighborhood Hits	159
SwissProt Accessions	Q810U4, Q80U33, Q8BLG8, Q8BX92, Q8BYJ8	Gene names	Nrcam, Kiaa0343
Domain Architecture
Description	Neuronal cell adhesion molecule precursor (Nr-CAM) (NgCAM-related cell adhesion molecule) (Ng-CAM-related) (mBravo).

L1CAM_MOUSE
NC score	0.641591 (rank : 21)	θ value	7.84624e-12 (rank : 30)
Query Neighborhood Hits	207	Target Neighborhood Hits	457	Shared Neighborhood Hits	165
SwissProt Accessions	P11627	Gene names	L1cam, Caml1
Domain Architecture
Description	Neural cell adhesion molecule L1 precursor (N-CAM L1) (CD171 antigen).

CHL1_HUMAN
NC score	0.632864 (rank : 22)	θ value	5.62301e-10 (rank : 46)
Query Neighborhood Hits	207	Target Neighborhood Hits	413	Shared Neighborhood Hits	145
SwissProt Accessions	O00533, Q2M3G2, Q59FY0	Gene names	CHL1, CALL
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Close homolog of L1).

NFASC_HUMAN
NC score	0.632252 (rank : 23)	θ value	8.11959e-09 (rank : 57)
Query Neighborhood Hits	207	Target Neighborhood Hits	497	Shared Neighborhood Hits	159
SwissProt Accessions	O94856, Q5T2F0, Q5T2F1, Q5T2F2, Q5T2F3, Q5T2F4, Q5T2F5, Q5T2F6, Q5T2F7, Q5T2F9, Q5T2G0, Q5W9F8, Q68DH3, Q6ZQV6, Q7Z3K1, Q96HT1, Q96K50	Gene names	NFASC, KIAA0756
Domain Architecture
Description	Neurofascin precursor.

PTPRD_HUMAN
NC score	0.629643 (rank : 24)	θ value	1.6813e-30 (rank : 4)
Query Neighborhood Hits	207	Target Neighborhood Hits	485	Shared Neighborhood Hits	174
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRD_MOUSE
NC score	0.625902 (rank : 25)	θ value	1.6813e-30 (rank : 5)
Query Neighborhood Hits	207	Target Neighborhood Hits	491	Shared Neighborhood Hits	171
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

CNTN3_HUMAN
NC score	0.625407 (rank : 26)	θ value	3.52202e-12 (rank : 27)
Query Neighborhood Hits	207	Target Neighborhood Hits	455	Shared Neighborhood Hits	156
SwissProt Accessions	Q9P232, Q9H039	Gene names	CNTN3, KIAA1496, PANG
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

CNTN3_MOUSE
NC score	0.623926 (rank : 27)	θ value	1.38499e-08 (rank : 60)
Query Neighborhood Hits	207	Target Neighborhood Hits	447	Shared Neighborhood Hits	157
SwissProt Accessions	Q07409	Gene names	Cntn3, Pang, Pcs
Domain Architecture	No domain graphic available
Description	Contactin-3 precursor (Brain-derived immunoglobulin superfamily protein 1) (BIG-1) (Plasmacytoma-associated neuronal glycoprotein).

PTPRF_HUMAN
NC score	0.619441 (rank : 28)	θ value	2.05525e-28 (rank : 8)
Query Neighborhood Hits	207	Target Neighborhood Hits	489	Shared Neighborhood Hits	172
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

CNTN2_HUMAN
NC score	0.617451 (rank : 29)	θ value	1.133e-10 (rank : 36)
Query Neighborhood Hits	207	Target Neighborhood Hits	440	Shared Neighborhood Hits	158
SwissProt Accessions	Q02246, P78432	Gene names	CNTN2, TAG1, TAX1
Domain Architecture
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

CHL1_MOUSE
NC score	0.616416 (rank : 30)	θ value	3.18553e-13 (rank : 25)
Query Neighborhood Hits	207	Target Neighborhood Hits	402	Shared Neighborhood Hits	141
SwissProt Accessions	P70232, Q8BS24, Q8C6W0, Q8C823, Q8VBY7	Gene names	Chl1, Call
Domain Architecture	No domain graphic available
Description	Neural cell adhesion molecule L1-like protein precursor (Cell adhesion molecule with homology to L1CAM) (Close homolog of L1) (Chl1-like protein).

CNTN2_MOUSE
NC score	0.615022 (rank : 31)	θ value	3.64472e-09 (rank : 52)
Query Neighborhood Hits	207	Target Neighborhood Hits	450	Shared Neighborhood Hits	157
SwissProt Accessions	Q61330, Q6NZJ4, Q7TSJ5	Gene names	Cntn2, Tax
Domain Architecture	No domain graphic available
Description	Contactin-2 precursor (Axonin-1) (Axonal glycoprotein TAG-1) (Transient axonal glycoprotein 1) (TAX-1).

PTPRS_HUMAN
NC score	0.612165 (rank : 32)	θ value	1.99067e-23 (rank : 13)
Query Neighborhood Hits	207	Target Neighborhood Hits	472	Shared Neighborhood Hits	171
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

CNTN5_HUMAN
NC score	0.608478 (rank : 33)	θ value	4.0297e-08 (rank : 63)
Query Neighborhood Hits	207	Target Neighborhood Hits	446	Shared Neighborhood Hits	155
SwissProt Accessions	O94779, O94780	Gene names	CNTN5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2) (hNB-2).

CNTN1_MOUSE
NC score	0.608300 (rank : 34)	θ value	2.52405e-10 (rank : 41)
Query Neighborhood Hits	207	Target Neighborhood Hits	422	Shared Neighborhood Hits	148
SwissProt Accessions	P12960, Q6NXV7, Q8BR42, Q8C6A0	Gene names	Cntn1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3).

CNTN1_HUMAN
NC score	0.607467 (rank : 35)	θ value	1.63604e-09 (rank : 49)
Query Neighborhood Hits	207	Target Neighborhood Hits	431	Shared Neighborhood Hits	148
SwissProt Accessions	Q12860, Q12861, Q14030, Q8N466	Gene names	CNTN1
Domain Architecture
Description	Contactin-1 precursor (Neural cell surface protein F3) (Glycoprotein gp135).

NFASC_MOUSE
NC score	0.604793 (rank : 36)	θ value	4.92598e-06 (rank : 92)
Query Neighborhood Hits	207	Target Neighborhood Hits	475	Shared Neighborhood Hits	151
SwissProt Accessions	Q810U3	Gene names	Nfasc
Domain Architecture
Description	Neurofascin precursor.

CNTN6_HUMAN
NC score	0.603100 (rank : 37)	θ value	2.61198e-07 (rank : 73)
Query Neighborhood Hits	207	Target Neighborhood Hits	422	Shared Neighborhood Hits	143
SwissProt Accessions	Q9UQ52	Gene names	CNTN6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (hNB-3).

CNTN5_MOUSE
NC score	0.600407 (rank : 38)	θ value	3.08544e-08 (rank : 62)
Query Neighborhood Hits	207	Target Neighborhood Hits	434	Shared Neighborhood Hits	147
SwissProt Accessions	P68500	Gene names	Cntn5
Domain Architecture	No domain graphic available
Description	Contactin-5 precursor (Neural recognition molecule NB-2).

CNTN4_HUMAN
NC score	0.597257 (rank : 39)	θ value	3.64472e-09 (rank : 53)
Query Neighborhood Hits	207	Target Neighborhood Hits	449	Shared Neighborhood Hits	146
SwissProt Accessions	Q8IWV2, Q8IX14, Q8TC35	Gene names	CNTN4
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

CNTN4_MOUSE
NC score	0.597240 (rank : 40)	θ value	4.30538e-10 (rank : 44)
Query Neighborhood Hits	207	Target Neighborhood Hits	445	Shared Neighborhood Hits	145
SwissProt Accessions	Q69Z26, Q8BRT6, Q8CBD3	Gene names	Cntn4, Kiaa3024
Domain Architecture	No domain graphic available
Description	Contactin-4 precursor (Brain-derived immunoglobulin superfamily protein 2) (BIG-2).

CNTN6_MOUSE
NC score	0.596669 (rank : 41)	θ value	5.26297e-08 (rank : 68)
Query Neighborhood Hits	207	Target Neighborhood Hits	429	Shared Neighborhood Hits	141
SwissProt Accessions	Q9JMB8, Q8C6X1	Gene names	Cntn6
Domain Architecture	No domain graphic available
Description	Contactin-6 precursor (Neural recognition molecule NB-3) (mNB-3).

MYPC3_HUMAN
NC score	0.581467 (rank : 42)	θ value	7.84624e-12 (rank : 31)
Query Neighborhood Hits	207	Target Neighborhood Hits	318	Shared Neighborhood Hits	129
SwissProt Accessions	Q14896, Q16410, Q6R2F7, Q9UE27, Q9UM53	Gene names	MYBPC3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

MYPC3_MOUSE
NC score	0.578949 (rank : 43)	θ value	4.59992e-12 (rank : 29)
Query Neighborhood Hits	207	Target Neighborhood Hits	310	Shared Neighborhood Hits	129
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

ROBO3_HUMAN
NC score	0.578724 (rank : 44)	θ value	2.13673e-09 (rank : 50)
Query Neighborhood Hits	207	Target Neighborhood Hits	570	Shared Neighborhood Hits	154
SwissProt Accessions	Q96MS0	Gene names	ROBO3
Domain Architecture
Description	Roundabout homolog 3 precursor (Roundabout-like protein 3).

MYPC2_MOUSE
NC score	0.577290 (rank : 45)	θ value	1.9326e-10 (rank : 38)
Query Neighborhood Hits	207	Target Neighborhood Hits	297	Shared Neighborhood Hits	116
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

PUNC_HUMAN
NC score	0.576686 (rank : 46)	θ value	6.43352e-06 (rank : 95)
Query Neighborhood Hits	207	Target Neighborhood Hits	449	Shared Neighborhood Hits	142
SwissProt Accessions	Q8IVU1, O95215	Gene names	PUNC
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

ROBO2_HUMAN
NC score	0.576365 (rank : 47)	θ value	5.26297e-08 (rank : 69)
Query Neighborhood Hits	207	Target Neighborhood Hits	479	Shared Neighborhood Hits	155
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

ROBO2_MOUSE
NC score	0.573838 (rank : 48)	θ value	3.41135e-07 (rank : 77)
Query Neighborhood Hits	207	Target Neighborhood Hits	504	Shared Neighborhood Hits	161
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

PUNC_MOUSE
NC score	0.572849 (rank : 49)	θ value	3.41135e-07 (rank : 76)
Query Neighborhood Hits	207	Target Neighborhood Hits	501	Shared Neighborhood Hits	137
SwissProt Accessions	Q8BQC3, O70246, Q792T2, Q9Z2S6	Gene names	Punc
Domain Architecture	No domain graphic available
Description	Putative neuronal cell adhesion molecule precursor.

ROBO3_MOUSE
NC score	0.569709 (rank : 50)	θ value	1.69304e-06 (rank : 86)
Query Neighborhood Hits	207	Target Neighborhood Hits	524	Shared Neighborhood Hits	149
SwissProt Accessions	Q9Z2I4	Gene names	Robo3, Rbig1
Domain Architecture
Description	Roundabout homolog 3 precursor (Retinoblastoma-inhibiting gene 1) (Rig-1).

ROBO1_MOUSE
NC score	0.568381 (rank : 51)	θ value	4.30538e-10 (rank : 45)
Query Neighborhood Hits	207	Target Neighborhood Hits	559	Shared Neighborhood Hits	155
SwissProt Accessions	O89026	Gene names	Robo1, Dutt1
Domain Architecture
Description	Roundabout homolog 1 precursor.

MYPC2_HUMAN
NC score	0.567960 (rank : 52)	θ value	8.67504e-11 (rank : 34)
Query Neighborhood Hits	207	Target Neighborhood Hits	316	Shared Neighborhood Hits	122
SwissProt Accessions	Q14324	Gene names	MYBPC2, MYBPCF
Domain Architecture
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

ROBO1_HUMAN
NC score	0.556292 (rank : 53)	θ value	1.80886e-08 (rank : 61)
Query Neighborhood Hits	207	Target Neighborhood Hits	529	Shared Neighborhood Hits	151
SwissProt Accessions	Q9Y6N7, Q7Z300, Q9BUS7	Gene names	ROBO1, DUTT1
Domain Architecture
Description	Roundabout homolog 1 precursor (H-Robo-1) (Deleted in U twenty twenty).

CDON_MOUSE
NC score	0.552041 (rank : 54)	θ value	3.41135e-07 (rank : 75)
Query Neighborhood Hits	207	Target Neighborhood Hits	410	Shared Neighborhood Hits	134
SwissProt Accessions	Q32MD9, O88971	Gene names	Cdon, Cdo
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

CDON_HUMAN
NC score	0.551753 (rank : 55)	θ value	9.92553e-07 (rank : 83)
Query Neighborhood Hits	207	Target Neighborhood Hits	412	Shared Neighborhood Hits	134
SwissProt Accessions	Q4KMG0, O14631	Gene names	CDON, CDO
Domain Architecture	No domain graphic available
Description	Cell adhesion molecule-related/down-regulated by oncogenes precursor.

BOC_HUMAN
NC score	0.543641 (rank : 56)	θ value	9.92553e-07 (rank : 82)
Query Neighborhood Hits	207	Target Neighborhood Hits	543	Shared Neighborhood Hits	139
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

MYPC1_HUMAN
NC score	0.539248 (rank : 57)	θ value	4.92598e-06 (rank : 91)
Query Neighborhood Hits	207	Target Neighborhood Hits	303	Shared Neighborhood Hits	117
SwissProt Accessions	Q00872, Q15497	Gene names	MYBPC1, MYBPCS
Domain Architecture
Description	Myosin-binding protein C, slow-type (Slow MyBP-C) (C-protein, skeletal muscle slow isoform).

BOC_MOUSE
NC score	0.538113 (rank : 58)	θ value	3.41135e-07 (rank : 74)
Query Neighborhood Hits	207	Target Neighborhood Hits	433	Shared Neighborhood Hits	130
SwissProt Accessions	Q6AZB0, Q6KAM5, Q6P5H3, Q7TMJ3, Q8CE73, Q8CE91, Q8R377, Q923W7	Gene names	Boc
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

NCAM2_MOUSE
NC score	0.535887 (rank : 59)	θ value	1.133e-10 (rank : 37)
Query Neighborhood Hits	207	Target Neighborhood Hits	472	Shared Neighborhood Hits	147
SwissProt Accessions	O35136, O35962	Gene names	Ncam2, Ocam, Rncam
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2) (RB-8 neural cell adhesion molecule) (R4B12).

NCAM2_HUMAN
NC score	0.528061 (rank : 60)	θ value	1.9326e-10 (rank : 39)
Query Neighborhood Hits	207	Target Neighborhood Hits	441	Shared Neighborhood Hits	145
SwissProt Accessions	O15394	Gene names	NCAM2, NCAM21
Domain Architecture
Description	Neural cell adhesion molecule 2 precursor (N-CAM 2).

USH2A_HUMAN
NC score	0.515133 (rank : 61)	θ value	5.06226e-27 (rank : 11)
Query Neighborhood Hits	207	Target Neighborhood Hits	600	Shared Neighborhood Hits	168
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

COCA1_MOUSE
NC score	0.509387 (rank : 62)	θ value	1.06045e-08 (rank : 58)
Query Neighborhood Hits	207	Target Neighborhood Hits	467	Shared Neighborhood Hits	155
SwissProt Accessions	Q60847, P70322	Gene names	Col12a1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

USH2A_MOUSE
NC score	0.498883 (rank : 63)	θ value	2.27234e-27 (rank : 10)
Query Neighborhood Hits	207	Target Neighborhood Hits	626	Shared Neighborhood Hits	169
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

COCA1_HUMAN
NC score	0.496848 (rank : 64)	θ value	2.79066e-09 (rank : 51)
Query Neighborhood Hits	207	Target Neighborhood Hits	458	Shared Neighborhood Hits	149
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

NCA11_HUMAN
NC score	0.486895 (rank : 65)	θ value	0.00102713 (rank : 119)
Query Neighborhood Hits	207	Target Neighborhood Hits	443	Shared Neighborhood Hits	130
SwissProt Accessions	P13591, Q15829, Q16180	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 140 kDa isoform precursor (N-CAM 140) (NCAM-140) (CD56 antigen).

MYBPH_MOUSE
NC score	0.484023 (rank : 66)	θ value	0.00390308 (rank : 129)
Query Neighborhood Hits	207	Target Neighborhood Hits	290	Shared Neighborhood Hits	110
SwissProt Accessions	P70402	Gene names	Mybph
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

NCA11_MOUSE
NC score	0.475449 (rank : 67)	θ value	0.00102713 (rank : 120)
Query Neighborhood Hits	207	Target Neighborhood Hits	661	Shared Neighborhood Hits	127
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NCA12_HUMAN
NC score	0.472265 (rank : 68)	θ value	0.000461057 (rank : 113)
Query Neighborhood Hits	207	Target Neighborhood Hits	437	Shared Neighborhood Hits	124
SwissProt Accessions	P13592, P13593	Gene names	NCAM1, NCAM
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120) (CD56 antigen).

NCA12_MOUSE
NC score	0.469640 (rank : 69)	θ value	0.0736092 (rank : 152)
Query Neighborhood Hits	207	Target Neighborhood Hits	399	Shared Neighborhood Hits	114
SwissProt Accessions	P13594, Q61950	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 120 kDa isoform precursor (N-CAM 120) (NCAM-120).

MYBPH_HUMAN
NC score	0.465922 (rank : 70)	θ value	0.0252991 (rank : 142)
Query Neighborhood Hits	207	Target Neighborhood Hits	256	Shared Neighborhood Hits	106
SwissProt Accessions	Q13203, Q16886, Q86YC5	Gene names	MYBPH
Domain Architecture
Description	Myosin-binding protein H (MyBP-H) (H-protein).

NPHN_HUMAN
NC score	0.462354 (rank : 71)	θ value	0.0431538 (rank : 146)
Query Neighborhood Hits	207	Target Neighborhood Hits	362	Shared Neighborhood Hits	114
SwissProt Accessions	O60500	Gene names	NPHS1, NPHN
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

IL6RB_HUMAN
NC score	0.453224 (rank : 72)	θ value	0.0736092 (rank : 151)
Query Neighborhood Hits	207	Target Neighborhood Hits	181	Shared Neighborhood Hits	124
SwissProt Accessions	P40189, Q9UQ41	Gene names	IL6ST
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin M receptor) (CD130 antigen) (CDw130).

ITB4_HUMAN
NC score	0.451957 (rank : 73)	θ value	1.17247e-07 (rank : 70)
Query Neighborhood Hits	207	Target Neighborhood Hits	458	Shared Neighborhood Hits	147
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ROBO4_MOUSE
NC score	0.449768 (rank : 74)	θ value	θ > 10 (rank : 770)
Query Neighborhood Hits	207	Target Neighborhood Hits	358	Shared Neighborhood Hits	101
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

ROBO4_HUMAN
NC score	0.448782 (rank : 75)	θ value	θ > 10 (rank : 769)
Query Neighborhood Hits	207	Target Neighborhood Hits	364	Shared Neighborhood Hits	103
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

OBSL1_HUMAN
NC score	0.446428 (rank : 76)	θ value	θ > 10 (rank : 659)
Query Neighborhood Hits	207	Target Neighborhood Hits	354	Shared Neighborhood Hits	85
SwissProt Accessions	O75147, Q96IW3	Gene names	OBSL1, KIAA0657
Domain Architecture	No domain graphic available
Description	Obscurin-like protein 1 precursor.

COEA1_MOUSE
NC score	0.441836 (rank : 77)	θ value	1.53129e-07 (rank : 72)
Query Neighborhood Hits	207	Target Neighborhood Hits	402	Shared Neighborhood Hits	107
SwissProt Accessions	Q80X19, Q8C6X3, Q9WV05	Gene names	Col14a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor.

NPHN_MOUSE
NC score	0.441263 (rank : 78)	θ value	0.163984 (rank : 155)
Query Neighborhood Hits	207	Target Neighborhood Hits	370	Shared Neighborhood Hits	119
SwissProt Accessions	Q9QZS7	Gene names	Nphs1, Nphn
Domain Architecture
Description	Nephrin precursor (Renal glomerulus-specific cell adhesion receptor).

TENR_HUMAN
NC score	0.432970 (rank : 79)	θ value	1.9326e-10 (rank : 40)
Query Neighborhood Hits	207	Target Neighborhood Hits	526	Shared Neighborhood Hits	142
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENN_MOUSE
NC score	0.427727 (rank : 80)	θ value	2.88788e-06 (rank : 90)
Query Neighborhood Hits	207	Target Neighborhood Hits	484	Shared Neighborhood Hits	137
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_MOUSE
NC score	0.423089 (rank : 81)	θ value	5.62301e-10 (rank : 47)
Query Neighborhood Hits	207	Target Neighborhood Hits	531	Shared Neighborhood Hits	139
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

HCFC2_MOUSE
NC score	0.417322 (rank : 82)	θ value	0.00134147 (rank : 123)
Query Neighborhood Hits	207	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	Q9D968	Gene names	Hcfc2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

MYPN_HUMAN
NC score	0.415421 (rank : 83)	θ value	θ > 10 (rank : 627)
Query Neighborhood Hits	207	Target Neighborhood Hits	418	Shared Neighborhood Hits	85
SwissProt Accessions	Q86TC9, Q5VV35, Q5VV36, Q86T37, Q8N3L4, Q96K90, Q96KF5	Gene names	MYPN, MYOP
Domain Architecture	No domain graphic available
Description	Myopalladin (145 kDa sarcomeric protein).

TITIN_HUMAN
NC score	0.414069 (rank : 84)	θ value	2.50074e-42 (rank : 3)
Query Neighborhood Hits	207	Target Neighborhood Hits	2923	Shared Neighborhood Hits	183
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

MYOTI_MOUSE
NC score	0.412689 (rank : 85)	θ value	θ > 10 (rank : 626)
Query Neighborhood Hits	207	Target Neighborhood Hits	297	Shared Neighborhood Hits	80
SwissProt Accessions	Q9JIF9	Gene names	Myot, Ttid
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein).

MYOTI_HUMAN
NC score	0.411018 (rank : 86)	θ value	θ > 10 (rank : 625)
Query Neighborhood Hits	207	Target Neighborhood Hits	292	Shared Neighborhood Hits	81
SwissProt Accessions	Q9UBF9	Gene names	MYOT, TTID
Domain Architecture	No domain graphic available
Description	Myotilin (Titin immunoglobulin domain protein) (Myofibrillar titin- like Ig domains protein) (57 kDa cytoskeletal protein).

MYPN_MOUSE
NC score	0.409845 (rank : 87)	θ value	θ > 10 (rank : 628)
Query Neighborhood Hits	207	Target Neighborhood Hits	421	Shared Neighborhood Hits	83
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

IL6RB_MOUSE
NC score	0.409812 (rank : 88)	θ value	0.0148317 (rank : 137)
Query Neighborhood Hits	207	Target Neighborhood Hits	168	Shared Neighborhood Hits	121
SwissProt Accessions	Q00560	Gene names	Il6st
Domain Architecture
Description	Interleukin-6 receptor beta chain precursor (IL-6R-beta) (Interleukin 6 signal transducer) (Membrane glycoprotein 130) (gp130) (CD130 antigen).

PTPRM_HUMAN
NC score	0.402934 (rank : 89)	θ value	3.64472e-09 (rank : 54)
Query Neighborhood Hits	207	Target Neighborhood Hits	244	Shared Neighborhood Hits	132
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

TENN_HUMAN
NC score	0.402380 (rank : 90)	θ value	3.29651e-10 (rank : 43)
Query Neighborhood Hits	207	Target Neighborhood Hits	453	Shared Neighborhood Hits	131
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

FGRL1_HUMAN
NC score	0.399904 (rank : 91)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	207	Target Neighborhood Hits	335	Shared Neighborhood Hits	82
SwissProt Accessions	Q8N441, Q6PJN1, Q9BXN7, Q9H4D7	Gene names	FGFRL1, FGFR5, FHFR
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5) (FGFR-like protein) (FGF homologous factor receptor).

PTPRM_MOUSE
NC score	0.398994 (rank : 92)	θ value	4.76016e-09 (rank : 55)
Query Neighborhood Hits	207	Target Neighborhood Hits	238	Shared Neighborhood Hits	132
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

FGRL1_MOUSE
NC score	0.398365 (rank : 93)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	207	Target Neighborhood Hits	325	Shared Neighborhood Hits	83
SwissProt Accessions	Q91V87, Q920C2, Q920C3	Gene names	Fgfrl1, Fgfr5
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor-like 1 precursor (FGF receptor-like protein 1) (Fibroblast growth factor receptor 5).

COEA1_HUMAN
NC score	0.397641 (rank : 94)	θ value	5.81887e-07 (rank : 80)
Query Neighborhood Hits	207	Target Neighborhood Hits	427	Shared Neighborhood Hits	122
SwissProt Accessions	Q05707, O00260, O00261, O00262, Q05708, Q5XJ18, Q96C67	Gene names	COL14A1, UND
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XIV) chain precursor (Undulin).

MAMC1_MOUSE
NC score	0.391059 (rank : 95)	θ value	θ > 10 (rank : 590)
Query Neighborhood Hits	207	Target Neighborhood Hits	357	Shared Neighborhood Hits	86
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC1_HUMAN
NC score	0.390524 (rank : 96)	θ value	θ > 10 (rank : 589)
Query Neighborhood Hits	207	Target Neighborhood Hits	357	Shared Neighborhood Hits	86
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

LIFR_HUMAN
NC score	0.390008 (rank : 97)	θ value	0.0431538 (rank : 145)
Query Neighborhood Hits	207	Target Neighborhood Hits	130	Shared Neighborhood Hits	88
SwissProt Accessions	P42702, Q6LCD9	Gene names	LIFR
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (CD118 antigen).

LIFR_MOUSE
NC score	0.389282 (rank : 98)	θ value	0.00509761 (rank : 130)
Query Neighborhood Hits	207	Target Neighborhood Hits	127	Shared Neighborhood Hits	87
SwissProt Accessions	P42703	Gene names	Lifr
Domain Architecture
Description	Leukemia inhibitory factor receptor precursor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD118 antigen).

MDGA1_HUMAN
NC score	0.386322 (rank : 99)	θ value	θ > 10 (rank : 595)
Query Neighborhood Hits	207	Target Neighborhood Hits	358	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

CO7A1_HUMAN
NC score	0.381366 (rank : 100)	θ value	5.99374e-20 (rank : 18)
Query Neighborhood Hits	207	Target Neighborhood Hits	807	Shared Neighborhood Hits	144
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

PTPRT_MOUSE
NC score	0.376782 (rank : 101)	θ value	4.0297e-08 (rank : 66)
Query Neighborhood Hits	207	Target Neighborhood Hits	219	Shared Neighborhood Hits	122
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRT_HUMAN
NC score	0.376148 (rank : 102)	θ value	4.0297e-08 (rank : 65)
Query Neighborhood Hits	207	Target Neighborhood Hits	217	Shared Neighborhood Hits	122
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

COKA1_HUMAN
NC score	0.375092 (rank : 103)	θ value	0.00665767 (rank : 131)
Query Neighborhood Hits	207	Target Neighborhood Hits	403	Shared Neighborhood Hits	113
SwissProt Accessions	Q9P218, Q4VXQ4, Q8WUT2, Q96CY9, Q9BQU6, Q9BQU7	Gene names	COL20A1, KIAA1510
Domain Architecture
Description	Collagen alpha-1(XX) chain precursor.

I12R2_HUMAN
NC score	0.364014 (rank : 104)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	207	Target Neighborhood Hits	163	Shared Neighborhood Hits	106
SwissProt Accessions	Q99665	Gene names	IL12RB2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

I12R2_MOUSE
NC score	0.360633 (rank : 105)	θ value	4.03905 (rank : 178)
Query Neighborhood Hits	207	Target Neighborhood Hits	143	Shared Neighborhood Hits	104
SwissProt Accessions	P97378	Gene names	Il12rb2
Domain Architecture
Description	Interleukin-12 receptor beta-2 chain precursor (IL-12 receptor beta-2) (IL-12R-beta2).

TENX_HUMAN
NC score	0.353588 (rank : 106)	θ value	7.58209e-15 (rank : 22)
Query Neighborhood Hits	207	Target Neighborhood Hits	789	Shared Neighborhood Hits	150
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

KALM_HUMAN
NC score	0.352517 (rank : 107)	θ value	1.38821 (rank : 168)
Query Neighborhood Hits	207	Target Neighborhood Hits	114	Shared Neighborhood Hits	77
SwissProt Accessions	P23352	Gene names	KAL1, ADMLX, KAL, KALIG1
Domain Architecture
Description	Anosmin-1 precursor (Kallmann syndrome protein) (Adhesion molecule- like X-linked).

CSF3R_HUMAN
NC score	0.348543 (rank : 108)	θ value	0.000786445 (rank : 115)
Query Neighborhood Hits	207	Target Neighborhood Hits	140	Shared Neighborhood Hits	95
SwissProt Accessions	Q99062	Gene names	CSF3R, GCSFR
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

LSAMP_MOUSE
NC score	0.346951 (rank : 109)	θ value	θ > 10 (rank : 571)
Query Neighborhood Hits	207	Target Neighborhood Hits	344	Shared Neighborhood Hits	80
SwissProt Accessions	Q8BLK3	Gene names	Lsamp
Domain Architecture	No domain graphic available
Description	Limbic system-associated membrane protein precursor (LSAMP).

LSAMP_HUMAN
NC score	0.344484 (rank : 110)	θ value	θ > 10 (rank : 570)
Query Neighborhood Hits	207	Target Neighborhood Hits	347	Shared Neighborhood Hits	80
SwissProt Accessions	Q13449, Q8IV49	Gene names	LSAMP, LAMP
Domain Architecture
Description	Limbic system-associated membrane protein precursor (LSAMP).

NEGR1_HUMAN
NC score	0.344368 (rank : 111)	θ value	θ > 10 (rank : 631)
Query Neighborhood Hits	207	Target Neighborhood Hits	346	Shared Neighborhood Hits	79
SwissProt Accessions	Q7Z3B1, Q5VT21, Q6UY06, Q8NAQ3	Gene names	NEGR1
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor.

PTPRU_HUMAN
NC score	0.343659 (rank : 112)	θ value	5.27518 (rank : 189)
Query Neighborhood Hits	207	Target Neighborhood Hits	237	Shared Neighborhood Hits	129
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

NEGR1_MOUSE
NC score	0.341693 (rank : 113)	θ value	θ > 10 (rank : 632)
Query Neighborhood Hits	207	Target Neighborhood Hits	349	Shared Neighborhood Hits	80
SwissProt Accessions	Q80Z24, Q3UHQ8, Q80T70	Gene names	Negr1, Kiaa3001, Ntra
Domain Architecture	No domain graphic available
Description	Neuronal growth regulator 1 precursor (Kilon protein) (Kindred of IgLON) (Neurotractin).

TENA_HUMAN
NC score	0.340903 (rank : 114)	θ value	4.0297e-08 (rank : 67)
Query Neighborhood Hits	207	Target Neighborhood Hits	631	Shared Neighborhood Hits	142
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

OPCM_HUMAN
NC score	0.338358 (rank : 115)	θ value	θ > 10 (rank : 660)
Query Neighborhood Hits	207	Target Neighborhood Hits	332	Shared Neighborhood Hits	81
SwissProt Accessions	Q14982	Gene names	OPCML, OBCAM
Domain Architecture
Description	Opioid-binding protein/cell adhesion molecule precursor (OBCAM) (Opioid-binding cell adhesion molecule) (OPCML).

PTPRK_MOUSE
NC score	0.334916 (rank : 116)	θ value	0.000121331 (rank : 105)
Query Neighborhood Hits	207	Target Neighborhood Hits	223	Shared Neighborhood Hits	114
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

NPTN_HUMAN
NC score	0.332641 (rank : 117)	θ value	θ > 10 (rank : 645)
Query Neighborhood Hits	207	Target Neighborhood Hits	212	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y639, Q59EJ9, Q6NVX7, Q9Y640	Gene names	NPTN, SDFR1, SDR1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

PTPRK_HUMAN
NC score	0.331805 (rank : 118)	θ value	5.44631e-05 (rank : 101)
Query Neighborhood Hits	207	Target Neighborhood Hits	228	Shared Neighborhood Hits	116
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

MALT1_HUMAN
NC score	0.331748 (rank : 119)	θ value	θ > 10 (rank : 588)
Query Neighborhood Hits	207	Target Neighborhood Hits	236	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UDY8, Q9NTB7, Q9ULX4	Gene names	MALT1, MLT
Domain Architecture
Description	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (EC 3.4.22.-) (MALT lymphoma-associated translocation) (Paracaspase).

TMIGD_HUMAN
NC score	0.329880 (rank : 120)	θ value	θ > 10 (rank : 837)
Query Neighborhood Hits	207	Target Neighborhood Hits	240	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UXZ0, Q6ZMC6	Gene names	TMIGD
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

NTRI_MOUSE
NC score	0.329602 (rank : 121)	θ value	θ > 10 (rank : 651)
Query Neighborhood Hits	207	Target Neighborhood Hits	342	Shared Neighborhood Hits	81
SwissProt Accessions	Q99PJ0	Gene names	Nt, Hnt
Domain Architecture
Description	Neurotrimin precursor.

TENA_MOUSE
NC score	0.326743 (rank : 122)	θ value	2.52405e-10 (rank : 42)
Query Neighborhood Hits	207	Target Neighborhood Hits	596	Shared Neighborhood Hits	133
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

PGBM_HUMAN
NC score	0.326207 (rank : 123)	θ value	θ > 10 (rank : 672)
Query Neighborhood Hits	207	Target Neighborhood Hits	1113	Shared Neighborhood Hits	119
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

NTRI_HUMAN
NC score	0.325505 (rank : 124)	θ value	θ > 10 (rank : 650)
Query Neighborhood Hits	207	Target Neighborhood Hits	344	Shared Neighborhood Hits	80
SwissProt Accessions	Q9P121, Q6UXJ3, Q86VJ9	Gene names	NT
Domain Architecture
Description	Neurotrimin precursor (hNT).

VCAM1_MOUSE
NC score	0.324986 (rank : 125)	θ value	θ > 10 (rank : 868)
Query Neighborhood Hits	207	Target Neighborhood Hits	320	Shared Neighborhood Hits	76
SwissProt Accessions	P29533	Gene names	Vcam1, Vcam-1
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1).

MAG_HUMAN
NC score	0.324595 (rank : 126)	θ value	θ > 10 (rank : 586)
Query Neighborhood Hits	207	Target Neighborhood Hits	278	Shared Neighborhood Hits	78
SwissProt Accessions	P20916	Gene names	MAG
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

MAG_MOUSE
NC score	0.323280 (rank : 127)	θ value	θ > 10 (rank : 587)
Query Neighborhood Hits	207	Target Neighborhood Hits	271	Shared Neighborhood Hits	78
SwissProt Accessions	P20917, P16880	Gene names	Mag
Domain Architecture
Description	Myelin-associated glycoprotein precursor (Siglec-4a).

VCAM1_HUMAN
NC score	0.323103 (rank : 128)	θ value	θ > 10 (rank : 867)
Query Neighborhood Hits	207	Target Neighborhood Hits	352	Shared Neighborhood Hits	77
SwissProt Accessions	P19320, Q6NUP8	Gene names	VCAM1, L1CAM
Domain Architecture
Description	Vascular cell adhesion protein 1 precursor (V-CAM 1) (CD106 antigen) (INCAM-100).

KAZD1_MOUSE
NC score	0.322505 (rank : 129)	θ value	θ > 10 (rank : 474)
Query Neighborhood Hits	207	Target Neighborhood Hits	281	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

PTPRB_HUMAN
NC score	0.320930 (rank : 130)	θ value	0.00102713 (rank : 121)
Query Neighborhood Hits	207	Target Neighborhood Hits	242	Shared Neighborhood Hits	103
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

FSTL5_HUMAN
NC score	0.320926 (rank : 131)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	207	Target Neighborhood Hits	347	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N475, Q9NSW7, Q9ULF7	Gene names	FSTL5, KIAA1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5).

NPTN_MOUSE
NC score	0.320486 (rank : 132)	θ value	θ > 10 (rank : 646)
Query Neighborhood Hits	207	Target Neighborhood Hits	216	Shared Neighborhood Hits	74
SwissProt Accessions	P97300, Q3U519, Q8C637, Q8C6H8	Gene names	Nptn, Sdfr1, Sdr1
Domain Architecture	No domain graphic available
Description	Neuroplastin precursor (Stromal cell-derived receptor 1) (SDR-1).

TMIGD_MOUSE
NC score	0.319352 (rank : 133)	θ value	θ > 10 (rank : 838)
Query Neighborhood Hits	207	Target Neighborhood Hits	234	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D7L8, Q8R202	Gene names	Tmigd
Domain Architecture	No domain graphic available
Description	Transmembrane and immunoglobulin domain-containing protein precursor.

PGBM_MOUSE
NC score	0.317494 (rank : 134)	θ value	θ > 10 (rank : 673)
Query Neighborhood Hits	207	Target Neighborhood Hits	1073	Shared Neighborhood Hits	119
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

FSTL5_MOUSE
NC score	0.314807 (rank : 135)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	207	Target Neighborhood Hits	355	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

FSTL4_HUMAN
NC score	0.314462 (rank : 136)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	207	Target Neighborhood Hits	344	Shared Neighborhood Hits	80
SwissProt Accessions	Q6MZW2, Q8TBU0, Q9UPU1	Gene names	FSTL4, KIAA1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4).

KIRR2_HUMAN
NC score	0.314275 (rank : 137)	θ value	θ > 10 (rank : 479)
Query Neighborhood Hits	207	Target Neighborhood Hits	321	Shared Neighborhood Hits	74
SwissProt Accessions	Q6UWL6, Q6P1R1, Q7Z5P1, Q7Z5P2, Q96IQ8, Q9H0T1	Gene names	KIRREL2, NEPH3
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3).

FSTL4_MOUSE
NC score	0.314146 (rank : 138)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	207	Target Neighborhood Hits	333	Shared Neighborhood Hits	77
SwissProt Accessions	Q5STE3, Q5DU03	Gene names	Fstl4, Kiaa1061
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 4 precursor (Follistatin-like 4) (m- D/Bsp120I 1-1).

SN_MOUSE
NC score	0.313334 (rank : 139)	θ value	θ > 10 (rank : 794)
Query Neighborhood Hits	207	Target Neighborhood Hits	416	Shared Neighborhood Hits	85
SwissProt Accessions	Q62230, O55216, Q62228, Q62229	Gene names	Sn, Sa
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (Sheep erythrocyte receptor) (SER) (CD169 antigen).

ICAM5_MOUSE
NC score	0.312639 (rank : 140)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	207	Target Neighborhood Hits	308	Shared Neighborhood Hits	73
SwissProt Accessions	Q60625	Gene names	Icam5, Tlcn
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

KIRR2_MOUSE
NC score	0.312130 (rank : 141)	θ value	θ > 10 (rank : 480)
Query Neighborhood Hits	207	Target Neighborhood Hits	326	Shared Neighborhood Hits	75
SwissProt Accessions	Q7TSU7, Q7TQ98	Gene names	Kirrel2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 2 precursor (Kin of irregular chiasm-like protein 2).

KAZD1_HUMAN
NC score	0.311930 (rank : 142)	θ value	θ > 10 (rank : 473)
Query Neighborhood Hits	207	Target Neighborhood Hits	248	Shared Neighborhood Hits	74
SwissProt Accessions	Q96I82, Q6ZMB1, Q9BQ73	Gene names	KAZALD1
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor.

LU_HUMAN
NC score	0.311802 (rank : 143)	θ value	θ > 10 (rank : 574)
Query Neighborhood Hits	207	Target Neighborhood Hits	283	Shared Neighborhood Hits	77
SwissProt Accessions	P50895, Q86VC7	Gene names	BCAM, LU, MSK19
Domain Architecture
Description	Lutheran blood group glycoprotein precursor (B-CAM cell surface glycoprotein) (Auberger B antigen) (F8/G253 antigen) (CD239 antigen).

HMCN1_HUMAN
NC score	0.311328 (rank : 144)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	207	Target Neighborhood Hits	983	Shared Neighborhood Hits	107
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

RAGE_HUMAN
NC score	0.311236 (rank : 145)	θ value	θ > 10 (rank : 755)
Query Neighborhood Hits	207	Target Neighborhood Hits	269	Shared Neighborhood Hits	78
SwissProt Accessions	Q15109, Q15279, Q9H2X7, Q9Y3R3	Gene names	AGER, RAGE
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

MUC18_HUMAN
NC score	0.309773 (rank : 146)	θ value	θ > 10 (rank : 620)
Query Neighborhood Hits	207	Target Neighborhood Hits	275	Shared Neighborhood Hits	73
SwissProt Accessions	P43121, O95812, Q59E86, Q6PHR3, Q6ZTR2	Gene names	MCAM, MUC18
Domain Architecture
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (S-endo 1 endothelial-associated antigen) (Cell surface glycoprotein P1H12) (CD146 antigen).

JAM3_HUMAN
NC score	0.306961 (rank : 147)	θ value	θ > 10 (rank : 469)
Query Neighborhood Hits	207	Target Neighborhood Hits	271	Shared Neighborhood Hits	71
SwissProt Accessions	Q9BX67, Q8WWL8, Q96FL1	Gene names	JAM3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

ICAM5_HUMAN
NC score	0.306385 (rank : 148)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	207	Target Neighborhood Hits	276	Shared Neighborhood Hits	74
SwissProt Accessions	Q9UMF0, Q9Y6F3	Gene names	ICAM5, TLCN, TLN
Domain Architecture
Description	Intercellular adhesion molecule 5 precursor (ICAM-5) (Telencephalin).

JAM3_MOUSE
NC score	0.304247 (rank : 149)	θ value	θ > 10 (rank : 470)
Query Neighborhood Hits	207	Target Neighborhood Hits	286	Shared Neighborhood Hits	73
SwissProt Accessions	Q9D8B7, Q8BT59, Q9D1M9, Q9EPK4	Gene names	Jam3
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule C precursor (JAM-C) (Junctional adhesion molecule 3) (JAM-3) (JAM-2).

SN_HUMAN
NC score	0.304127 (rank : 150)	θ value	θ > 10 (rank : 793)
Query Neighborhood Hits	207	Target Neighborhood Hits	434	Shared Neighborhood Hits	80
SwissProt Accessions	Q9BZZ2, Q96DL4, Q9GZS5, Q9H1H6, Q9H1H7, Q9H7L7	Gene names	SN
Domain Architecture
Description	Sialoadhesin precursor (Sialic acid-binding Ig-like lectin-1) (Siglec- 1) (CD169 antigen).

SORL_HUMAN
NC score	0.299226 (rank : 151)	θ value	1.25267e-09 (rank : 48)
Query Neighborhood Hits	207	Target Neighborhood Hits	440	Shared Neighborhood Hits	124
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

TARSH_HUMAN
NC score	0.299031 (rank : 152)	θ value	0.00298849 (rank : 128)
Query Neighborhood Hits	207	Target Neighborhood Hits	768	Shared Neighborhood Hits	109
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

KIRR1_HUMAN
NC score	0.297656 (rank : 153)	θ value	θ > 10 (rank : 477)
Query Neighborhood Hits	207	Target Neighborhood Hits	401	Shared Neighborhood Hits	74
SwissProt Accessions	Q96J84, Q5XKC6, Q7Z696, Q7Z7N8, Q8TB15, Q9H9N1, Q9NVA5	Gene names	KIRREL, NEPH1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

CD22_MOUSE
NC score	0.297617 (rank : 154)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	207	Target Neighborhood Hits	331	Shared Neighborhood Hits	72
SwissProt Accessions	P35329, Q9JHL2, Q9JJX9, Q9JJY0, Q9JJY1, Q9R056, Q9R094, Q9WU51	Gene names	Cd22, Lyb-8
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

BASI_HUMAN
NC score	0.296223 (rank : 155)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	207	Target Neighborhood Hits	211	Shared Neighborhood Hits	67
SwissProt Accessions	P35613, Q7Z796, Q8IZL7	Gene names	BSG
Domain Architecture
Description	Basigin precursor (Leukocyte activation antigen M6) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (5F7) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (OK blood group antigen) (CD147 antigen).

PTK7_HUMAN
NC score	0.295594 (rank : 156)	θ value	θ > 10 (rank : 700)
Query Neighborhood Hits	207	Target Neighborhood Hits	1103	Shared Neighborhood Hits	118
SwissProt Accessions	Q13308, Q13417	Gene names	PTK7, CCK4
Domain Architecture
Description	Tyrosine-protein kinase-like 7 precursor (Colon carcinoma kinase 4) (CCK-4).

JAM1_HUMAN
NC score	0.295584 (rank : 157)	θ value	θ > 10 (rank : 465)
Query Neighborhood Hits	207	Target Neighborhood Hits	294	Shared Neighborhood Hits	74
SwissProt Accessions	Q9Y624	Gene names	F11R, JAM1, JCAM
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (Platelet adhesion molecule 1) (PAM-1) (Platelet F11 receptor) (CD321 antigen).

MUC18_MOUSE
NC score	0.295131 (rank : 158)	θ value	θ > 10 (rank : 621)
Query Neighborhood Hits	207	Target Neighborhood Hits	292	Shared Neighborhood Hits	72
SwissProt Accessions	Q8R2Y2, Q9EPF1, Q9ESS7, Q9JHQ2, Q9JHQ3	Gene names	Mcam, Muc18
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein MUC18 precursor (Melanoma-associated antigen MUC18) (Melanoma cell adhesion molecule) (Gicerin).

CI094_HUMAN
NC score	0.294086 (rank : 159)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	207	Target Neighborhood Hits	310	Shared Neighborhood Hits	73
SwissProt Accessions	Q496M8, Q496M6, Q5VZT8, Q8NAI9	Gene names	C9orf94
Domain Architecture	No domain graphic available
Description	Protein C9orf94 precursor.

RAGE_MOUSE
NC score	0.293851 (rank : 160)	θ value	θ > 10 (rank : 756)
Query Neighborhood Hits	207	Target Neighborhood Hits	295	Shared Neighborhood Hits	75
SwissProt Accessions	Q62151	Gene names	Ager, Rage
Domain Architecture
Description	Advanced glycosylation end product-specific receptor precursor (Receptor for advanced glycosylation end products).

KIRR1_MOUSE
NC score	0.291810 (rank : 161)	θ value	θ > 10 (rank : 478)
Query Neighborhood Hits	207	Target Neighborhood Hits	403	Shared Neighborhood Hits	73
SwissProt Accessions	Q80W68, Q8CIJ4, Q8CJ59, Q923L4	Gene names	Kirrel1, Kirrel, Neph1
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 1 precursor (Kin of irregular chiasm-like protein 1) (Nephrin-like protein 1).

HCFC2_HUMAN
NC score	0.290424 (rank : 162)	θ value	0.000786445 (rank : 117)
Query Neighborhood Hits	207	Target Neighborhood Hits	154	Shared Neighborhood Hits	91
SwissProt Accessions	Q9Y5Z7	Gene names	HCFC2
Domain Architecture	No domain graphic available
Description	Host cell factor 2 (HCF-2) (C2 factor).

KIRR3_HUMAN
NC score	0.290296 (rank : 163)	θ value	θ > 10 (rank : 481)
Query Neighborhood Hits	207	Target Neighborhood Hits	302	Shared Neighborhood Hits	72
SwissProt Accessions	Q8IZU9, Q6UWJ9, Q6UWL5, Q96JG0	Gene names	KIRREL3, KIAA1867, NEPH2
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3) (Nephrin-like 2).

SORL_MOUSE
NC score	0.287135 (rank : 164)	θ value	4.45536e-07 (rank : 79)
Query Neighborhood Hits	207	Target Neighborhood Hits	439	Shared Neighborhood Hits	119
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

CD22_HUMAN
NC score	0.286182 (rank : 165)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	207	Target Neighborhood Hits	365	Shared Neighborhood Hits	76
SwissProt Accessions	P20273, O95699, O95701, O95702, O95703, Q01665, Q92872, Q92873, Q9UQA6, Q9UQA7, Q9UQA8, Q9UQA9, Q9UQB0, Q9Y2A6	Gene names	CD22
Domain Architecture
Description	B-cell receptor CD22 precursor (Leu-14) (B-lymphocyte cell adhesion molecule) (BL-CAM) (Siglec-2).

BASI_MOUSE
NC score	0.285994 (rank : 166)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	207	Target Neighborhood Hits	238	Shared Neighborhood Hits	68
SwissProt Accessions	P18572, Q6LDB0, Q7TSC0	Gene names	Bsg
Domain Architecture
Description	Basigin precursor (Basic immunoglobulin superfamily) (Membrane glycoprotein gp42) (HT7 antigen) (CD147 antigen).

KIRR3_MOUSE
NC score	0.284381 (rank : 167)	θ value	θ > 10 (rank : 482)
Query Neighborhood Hits	207	Target Neighborhood Hits	292	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BR86, Q6P555, Q810H3, Q8BGQ5, Q8BRS8	Gene names	Kirrel3, Kiaa1867
Domain Architecture	No domain graphic available
Description	Kin of IRRE-like protein 3 precursor (Kin of irregular chiasm-like protein 3).

JAM1_MOUSE
NC score	0.283855 (rank : 168)	θ value	θ > 10 (rank : 466)
Query Neighborhood Hits	207	Target Neighborhood Hits	287	Shared Neighborhood Hits	75
SwissProt Accessions	O88792	Gene names	F11r, Jam1, Jcam, Jcam1
Domain Architecture
Description	Junctional adhesion molecule A precursor (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD321 antigen).

CEAM5_HUMAN
NC score	0.276803 (rank : 169)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	207	Target Neighborhood Hits	343	Shared Neighborhood Hits	77
SwissProt Accessions	P06731	Gene names	CEACAM5, CEA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 5 precursor (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD66e antigen).

MUSK_MOUSE
NC score	0.276000 (rank : 170)	θ value	θ > 10 (rank : 623)
Query Neighborhood Hits	207	Target Neighborhood Hits	1057	Shared Neighborhood Hits	119
SwissProt Accessions	Q61006, Q61005, Q61987, Q61988	Gene names	Musk, Nsk2
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific kinase receptor) (MuSK).

MUSK_HUMAN
NC score	0.275696 (rank : 171)	θ value	θ > 10 (rank : 622)
Query Neighborhood Hits	207	Target Neighborhood Hits	1074	Shared Neighborhood Hits	119
SwissProt Accessions	O15146	Gene names	MUSK
Domain Architecture	No domain graphic available
Description	Muscle, skeletal receptor tyrosine protein kinase precursor (EC 2.7.10.1) (Muscle-specific tyrosine protein kinase receptor) (Muscle-specific kinase receptor) (MuSK).

LRIG2_HUMAN
NC score	0.274433 (rank : 172)	θ value	θ > 10 (rank : 553)
Query Neighborhood Hits	207	Target Neighborhood Hits	595	Shared Neighborhood Hits	91
SwissProt Accessions	O94898, Q9NSN2	Gene names	LRIG2, KIAA0806, LIG2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor (LIG-2).

LRIG2_MOUSE
NC score	0.274128 (rank : 173)	θ value	θ > 10 (rank : 554)
Query Neighborhood Hits	207	Target Neighborhood Hits	586	Shared Neighborhood Hits	91
SwissProt Accessions	Q52KR2, Q69ZY8	Gene names	Lrig2, Kiaa0806
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 2 precursor.

LRIG1_HUMAN
NC score	0.273630 (rank : 174)	θ value	θ > 10 (rank : 551)
Query Neighborhood Hits	207	Target Neighborhood Hits	654	Shared Neighborhood Hits	88
SwissProt Accessions	Q96JA1, Q6IQ51, Q96CF9, Q9BYB8, Q9UFI4	Gene names	LRIG1, LIG1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

FCRL5_HUMAN
NC score	0.272929 (rank : 175)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	207	Target Neighborhood Hits	267	Shared Neighborhood Hits	64
SwissProt Accessions	Q96RD9, Q495Q2, Q495Q4, Q5VYK9, Q6UY46	Gene names	FCRL5, FCRH5, IRTA2
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 5 precursor (Immunoglobulin receptor translocation-associated gene 2 protein) (BXMAS1) (CD307 antigen).

JAM2_HUMAN
NC score	0.272734 (rank : 176)	θ value	θ > 10 (rank : 467)
Query Neighborhood Hits	207	Target Neighborhood Hits	304	Shared Neighborhood Hits	79
SwissProt Accessions	P57087, Q6UXG6, Q6YNC1	Gene names	JAM2, C21orf43, VEJAM
Domain Architecture
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

PTPRJ_MOUSE
NC score	0.271908 (rank : 177)	θ value	0.00134147 (rank : 124)
Query Neighborhood Hits	207	Target Neighborhood Hits	188	Shared Neighborhood Hits	85
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

CEA20_HUMAN
NC score	0.270127 (rank : 178)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	207	Target Neighborhood Hits	251	Shared Neighborhood Hits	69
SwissProt Accessions	Q6UY09	Gene names	CEACAM20
Domain Architecture	No domain graphic available
Description	Carcinoembryonic antigen-related cell adhesion molecule 20 precursor.

MFA3L_HUMAN
NC score	0.269858 (rank : 179)	θ value	θ > 10 (rank : 603)
Query Neighborhood Hits	207	Target Neighborhood Hits	230	Shared Neighborhood Hits	75
SwissProt Accessions	O75121, Q6TNA8, Q9BVE1, Q9BXK0	Gene names	MFAP3L, KIAA0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor (Protein kinase NYD-SP9).

IBP7_MOUSE
NC score	0.269025 (rank : 180)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	207	Target Neighborhood Hits	230	Shared Neighborhood Hits	72
SwissProt Accessions	Q61581, O88812, Q9EQW0	Gene names	Igfbp7, Mac25
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein).

IBP7_HUMAN
NC score	0.268879 (rank : 181)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	207	Target Neighborhood Hits	220	Shared Neighborhood Hits	69
SwissProt Accessions	Q16270, Q07822	Gene names	IGFBP7, MAC25, PSF
Domain Architecture
Description	Insulin-like growth factor-binding protein 7 precursor (IGFBP-7) (IBP- 7) (IGF-binding protein 7) (MAC25 protein) (Prostacyclin-stimulating factor) (PGI2-stimulating factor) (IGFBP-rP1).

LRIG1_MOUSE
NC score	0.268520 (rank : 182)	θ value	θ > 10 (rank : 552)
Query Neighborhood Hits	207	Target Neighborhood Hits	627	Shared Neighborhood Hits	87
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

LRIG3_MOUSE
NC score	0.266022 (rank : 183)	θ value	θ > 10 (rank : 556)
Query Neighborhood Hits	207	Target Neighborhood Hits	611	Shared Neighborhood Hits	91
SwissProt Accessions	Q6P1C6, Q6ZPE6, Q8BRF0, Q8BS51, Q8C5E4	Gene names	Lrig3, Kiaa3016
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor.

FCRL2_HUMAN
NC score	0.265458 (rank : 184)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	207	Target Neighborhood Hits	251	Shared Neighborhood Hits	69
SwissProt Accessions	Q96LA5, Q6NTA1, Q9BZI4, Q9BZI5, Q9BZI6	Gene names	FCRL2, FCRH2, IFGP4, IRTA4, SPAP1
Domain Architecture	No domain graphic available
Description	Fc receptor-like protein 2 precursor (SH2 domain-containing phosphatase anchor protein 1) (Fc receptor homolog 2) (FcRH2) (Immunoglobulin receptor translocation-associated 4 protein).

LRIG3_HUMAN
NC score	0.263852 (rank : 185)	θ value	θ > 10 (rank : 555)
Query Neighborhood Hits	207	Target Neighborhood Hits	601	Shared Neighborhood Hits	92
SwissProt Accessions	Q6UXM1, Q6UXL7, Q8NC72	Gene names	LRIG3, LIG3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 3 precursor (LIG-3).

CEAM1_MOUSE
NC score	0.263563 (rank : 186)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	207	Target Neighborhood Hits	326	Shared Neighborhood Hits	73
SwissProt Accessions	P31809	Gene names	Ceacam1, Bgp, Bgp1, Bgpd
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (Murine hepatitis virus receptor) (MHV-R) (Biliary glycoprotein D).

PTPRJ_HUMAN
NC score	0.263166 (rank : 187)	θ value	0.47712 (rank : 159)
Query Neighborhood Hits	207	Target Neighborhood Hits	207	Shared Neighborhood Hits	96
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

VSIG2_HUMAN
NC score	0.261605 (rank : 188)	θ value	θ > 10 (rank : 877)
Query Neighborhood Hits	207	Target Neighborhood Hits	321	Shared Neighborhood Hits	74
SwissProt Accessions	Q96IQ7, O95791, Q9NX42	Gene names	VSIG2, CTH, CTXL
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

PTPRV_MOUSE
NC score	0.260673 (rank : 189)	θ value	θ > 10 (rank : 744)
Query Neighborhood Hits	207	Target Neighborhood Hits	179	Shared Neighborhood Hits	75
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

TYRO3_HUMAN
NC score	0.260046 (rank : 190)	θ value	0.00134147 (rank : 125)
Query Neighborhood Hits	207	Target Neighborhood Hits	995	Shared Neighborhood Hits	135
SwissProt Accessions	Q06418, O14953, Q86VR3	Gene names	TYRO3, BYK, DTK, RSE, SKY
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine- protein kinase DTK) (Protein-tyrosine kinase byk).

NRG2_HUMAN
NC score	0.259295 (rank : 191)	θ value	8.99809 (rank : 205)
Query Neighborhood Hits	207	Target Neighborhood Hits	419	Shared Neighborhood Hits	83
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

JAM2_MOUSE
NC score	0.258789 (rank : 192)	θ value	θ > 10 (rank : 468)
Query Neighborhood Hits	207	Target Neighborhood Hits	292	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JI59, Q8C5K9, Q8CE95	Gene names	Jam2, Vejam
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule B precursor (JAM-B) (Junctional adhesion molecule 2) (Vascular endothelial junction-associated molecule) (VE- JAM) (CD322 antigen).

NRG2_MOUSE
NC score	0.257615 (rank : 193)	θ value	8.99809 (rank : 206)
Query Neighborhood Hits	207	Target Neighborhood Hits	392	Shared Neighborhood Hits	81
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

MYLK_HUMAN
NC score	0.257464 (rank : 194)	θ value	9.92553e-07 (rank : 84)
Query Neighborhood Hits	207	Target Neighborhood Hits	1328	Shared Neighborhood Hits	138
SwissProt Accessions	Q15746, O95796, O95797, O95798, O95799, Q14844, Q16794, Q5MY99, Q5MYA0, Q7Z4J0, Q9C0L5, Q9UBG5, Q9UIT9	Gene names	MYLK, MLCK
Domain Architecture
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

TYRO3_MOUSE
NC score	0.256325 (rank : 195)	θ value	0.00102713 (rank : 122)
Query Neighborhood Hits	207	Target Neighborhood Hits	1007	Shared Neighborhood Hits	138
SwissProt Accessions	P55144, O09070, O09080, P70285, Q60752, Q62482, Q62483, Q62484, Q78E85, Q78E87	Gene names	Tyro3, Dtk, Rse
Domain Architecture
Description	Tyrosine-protein kinase receptor TYRO3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase DTK) (TK19-2) (Etk2/tyro3).

MYLK_MOUSE
NC score	0.255859 (rank : 196)	θ value	1.69304e-06 (rank : 85)
Query Neighborhood Hits	207	Target Neighborhood Hits	1489	Shared Neighborhood Hits	141
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

CSF3R_MOUSE
NC score	0.254560 (rank : 197)	θ value	8.99809 (rank : 199)
Query Neighborhood Hits	207	Target Neighborhood Hits	104	Shared Neighborhood Hits	72
SwissProt Accessions	P40223	Gene names	Csf3r, Csfgr
Domain Architecture
Description	Granulocyte colony-stimulating factor receptor precursor (G-CSF-R) (CD114 antigen).

OBSCN_HUMAN
NC score	0.253210 (rank : 198)	θ value	2.88788e-06 (rank : 89)
Query Neighborhood Hits	207	Target Neighborhood Hits	1931	Shared Neighborhood Hits	145
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

IGS4B_MOUSE
NC score	0.252932 (rank : 199)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	207	Target Neighborhood Hits	328	Shared Neighborhood Hits	72
SwissProt Accessions	Q99N28, Q8BSQ8, Q8K1H8	Gene names	Igsf4b, Necl1, Syncam3, Tsll1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (Necl-1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3).

EPHB6_HUMAN
NC score	0.252542 (rank : 200)	θ value	0.0961366 (rank : 153)
Query Neighborhood Hits	207	Target Neighborhood Hits	912	Shared Neighborhood Hits	138
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

SIG11_HUMAN
NC score	0.249556 (rank : 201)	θ value	θ > 10 (rank : 781)
Query Neighborhood Hits	207	Target Neighborhood Hits	273	Shared Neighborhood Hits	75
SwissProt Accessions	Q96RL6	Gene names	SIGLEC11
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 11 precursor (Siglec-11) (Sialic acid-binding lectin 11).

IGS4B_HUMAN
NC score	0.248961 (rank : 202)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	207	Target Neighborhood Hits	305	Shared Neighborhood Hits	73
SwissProt Accessions	Q8N126, Q9NVJ5, Q9UJP1	Gene names	IGSF4B, NECL1, SYNCAM3, TSLL1
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 4B precursor (Nectin-like protein 1) (TSLC1-like protein 1) (Synaptic cell adhesion molecule 3) (Brain immunoglobulin receptor).

VSIG2_MOUSE
NC score	0.248512 (rank : 203)	θ value	θ > 10 (rank : 878)
Query Neighborhood Hits	207	Target Neighborhood Hits	316	Shared Neighborhood Hits	70
SwissProt Accessions	Q9Z109, Q9CVA4, Q9D0T4	Gene names	Vsig2, Ctm, Ctxl
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 2 precursor (CT- like protein) (Cortical thymocyte-like protein).

EPHB6_MOUSE
NC score	0.248396 (rank : 204)	θ value	0.0193708 (rank : 138)
Query Neighborhood Hits	207	Target Neighborhood Hits	906	Shared Neighborhood Hits	134
SwissProt Accessions	O08644, Q8BN76, Q8K0A9	Gene names	Ephb6, Cekl
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (MEP).

EPHA7_HUMAN
NC score	0.245789 (rank : 205)	θ value	3.19293e-05 (rank : 98)
Query Neighborhood Hits	207	Target Neighborhood Hits	1053	Shared Neighborhood Hits	148
SwissProt Accessions	Q15375, Q59G40, Q5VTU0, Q8N368, Q9H124	Gene names	EPHA7, EHK3, HEK11
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Receptor protein- tyrosine kinase HEK11).

EPHA7_MOUSE
NC score	0.244806 (rank : 206)	θ value	5.44631e-05 (rank : 100)
Query Neighborhood Hits	207	Target Neighborhood Hits	1025	Shared Neighborhood Hits	148
SwissProt Accessions	Q61772, Q61505, Q61773, Q61774	Gene names	Epha7, Ebk, Ehk3, Mdk1
Domain Architecture
Description	Ephrin type-A receptor 7 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-3) (EPH homology kinase 3) (Embryonic brain kinase) (EBK) (Developmental kinase 1) (MDK-1).

SIG10_HUMAN
NC score	0.244411 (rank : 207)	θ value	θ > 10 (rank : 780)
Query Neighborhood Hits	207	Target Neighborhood Hits	363	Shared Neighborhood Hits	74
SwissProt Accessions	Q96LC7, Q6UXI8, Q96G54, Q96LC8	Gene names	SIGLEC10, SLG2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 10 precursor (Siglec-10) (Siglec- like protein 2).

EPHA4_MOUSE
NC score	0.241673 (rank : 208)	θ value	0.000270298 (rank : 108)
Query Neighborhood Hits	207	Target Neighborhood Hits	982	Shared Neighborhood Hits	149
SwissProt Accessions	Q03137	Gene names	Epha4, Sek, Sek1
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (MPK-3).

MERTK_HUMAN
NC score	0.241631 (rank : 209)	θ value	0.00035302 (rank : 110)
Query Neighborhood Hits	207	Target Neighborhood Hits	988	Shared Neighborhood Hits	125
SwissProt Accessions	Q12866, Q9HBB4	Gene names	MERTK, MER
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

EPHA8_MOUSE
NC score	0.239978 (rank : 210)	θ value	7.1131e-05 (rank : 103)
Query Neighborhood Hits	207	Target Neighborhood Hits	969	Shared Neighborhood Hits	144
SwissProt Accessions	O09127	Gene names	Epha8, Eek
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase).

MERTK_MOUSE
NC score	0.239134 (rank : 211)	θ value	0.00035302 (rank : 111)
Query Neighborhood Hits	207	Target Neighborhood Hits	974	Shared Neighborhood Hits	129
SwissProt Accessions	Q60805, Q62194	Gene names	Mertk, Mer
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase MER precursor (EC 2.7.10.1) (C- mer) (Receptor tyrosine kinase MerTK).

EPHA4_HUMAN
NC score	0.238812 (rank : 212)	θ value	0.000602161 (rank : 114)
Query Neighborhood Hits	207	Target Neighborhood Hits	975	Shared Neighborhood Hits	146
SwissProt Accessions	P54764	Gene names	EPHA4, HEK8, SEK
Domain Architecture
Description	Ephrin type-A receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor SEK) (Receptor protein-tyrosine kinase HEK8).

EPHB3_MOUSE
NC score	0.238789 (rank : 213)	θ value	0.00102713 (rank : 118)
Query Neighborhood Hits	207	Target Neighborhood Hits	996	Shared Neighborhood Hits	144
SwissProt Accessions	P54754, Q62214	Gene names	Ephb3, Etk2, Mdk5, Sek4
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-5) (Developmental kinase 5) (SEK-4).

EPHA3_MOUSE
NC score	0.238502 (rank : 214)	θ value	2.21117e-06 (rank : 87)
Query Neighborhood Hits	207	Target Neighborhood Hits	1009	Shared Neighborhood Hits	147
SwissProt Accessions	P29319	Gene names	Epha3, Etk1, Mek4, Tyro4
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (MEK4).

EPHA8_HUMAN
NC score	0.237665 (rank : 215)	θ value	3.19293e-05 (rank : 99)
Query Neighborhood Hits	207	Target Neighborhood Hits	956	Shared Neighborhood Hits	143
SwissProt Accessions	P29322, Q9NUA9, Q9P269	Gene names	EPHA8, EEK, KIAA1459
Domain Architecture
Description	Ephrin type-A receptor 8 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EEK) (EPH- and ELK-related kinase) (HEK3).

EPHB3_HUMAN
NC score	0.235769 (rank : 216)	θ value	0.0563607 (rank : 148)
Query Neighborhood Hits	207	Target Neighborhood Hits	996	Shared Neighborhood Hits	145
SwissProt Accessions	P54753, Q7Z740	Gene names	EPHB3, ETK2, HEK2
Domain Architecture
Description	Ephrin type-B receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HEK-2).

TIE1_MOUSE
NC score	0.235592 (rank : 217)	θ value	9.29e-05 (rank : 104)
Query Neighborhood Hits	207	Target Neighborhood Hits	1266	Shared Neighborhood Hits	151
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

SPEG_MOUSE
NC score	0.234870 (rank : 218)	θ value	0.813845 (rank : 164)
Query Neighborhood Hits	207	Target Neighborhood Hits	1959	Shared Neighborhood Hits	133
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

EPHB4_MOUSE
NC score	0.233984 (rank : 219)	θ value	7.59969e-07 (rank : 81)
Query Neighborhood Hits	207	Target Neighborhood Hits	1013	Shared Neighborhood Hits	145
SwissProt Accessions	P54761, Q60627	Gene names	Ephb4, Htk, Mdk2, Myk1
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor MDK-2) (Developmental kinase 2) (Tyrosine kinase MYK- 1).

VGFR1_HUMAN
NC score	0.232945 (rank : 220)	θ value	θ > 10 (rank : 869)
Query Neighborhood Hits	207	Target Neighborhood Hits	1109	Shared Neighborhood Hits	116
SwissProt Accessions	P17948, O60722, P16057, Q12954	Gene names	FLT1, FLT, FRT
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Vascular permeability factor receptor) (Tyrosine-protein kinase receptor FLT) (Flt-1) (Tyrosine-protein kinase FRT) (Fms-like tyrosine kinase 1).

EPHA5_HUMAN
NC score	0.232448 (rank : 221)	θ value	6.43352e-06 (rank : 94)
Query Neighborhood Hits	207	Target Neighborhood Hits	1009	Shared Neighborhood Hits	150
SwissProt Accessions	P54756	Gene names	EPHA5, EHK1, HEK7
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Receptor protein- tyrosine kinase HEK7).

SPEG_HUMAN
NC score	0.232014 (rank : 222)	θ value	2.36792 (rank : 170)
Query Neighborhood Hits	207	Target Neighborhood Hits	1762	Shared Neighborhood Hits	131
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

EPHA3_HUMAN
NC score	0.231850 (rank : 223)	θ value	1.87187e-05 (rank : 97)
Query Neighborhood Hits	207	Target Neighborhood Hits	1005	Shared Neighborhood Hits	146
SwissProt Accessions	P29320, Q9H2V3, Q9H2V4	Gene names	EPHA3, ETK, ETK1, HEK
Domain Architecture
Description	Ephrin type-A receptor 3 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ETK1) (HEK) (HEK4).

TIE1_HUMAN
NC score	0.231718 (rank : 224)	θ value	1.17247e-07 (rank : 71)
Query Neighborhood Hits	207	Target Neighborhood Hits	1241	Shared Neighborhood Hits	151
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

VGFR1_MOUSE
NC score	0.230726 (rank : 225)	θ value	θ > 10 (rank : 870)
Query Neighborhood Hits	207	Target Neighborhood Hits	1118	Shared Neighborhood Hits	117
SwissProt Accessions	P35969, O55094, Q61517	Gene names	Flt1, Emrk2, Flt
Domain Architecture
Description	Vascular endothelial growth factor receptor 1 precursor (EC 2.7.10.1) (VEGFR-1) (Tyrosine-protein kinase receptor FLT) (FLT-1) (Embryonic receptor kinase 2).

EPHB4_HUMAN
NC score	0.230036 (rank : 226)	θ value	4.45536e-07 (rank : 78)
Query Neighborhood Hits	207	Target Neighborhood Hits	1056	Shared Neighborhood Hits	145
SwissProt Accessions	P54760, Q9BTA5, Q9BXP0	Gene names	EPHB4, HTK
Domain Architecture
Description	Ephrin type-B receptor 4 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor HTK).

CEAM1_HUMAN
NC score	0.229473 (rank : 227)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	207	Target Neighborhood Hits	348	Shared Neighborhood Hits	73
SwissProt Accessions	P13688, O60430, Q13858, Q15600, Q9UQV9	Gene names	CEACAM1, BGP, BGP1
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 1 precursor (Biliary glycoprotein 1) (BGP-1) (CD66 antigen) (CD66a antigen).

TIE2_HUMAN
NC score	0.229090 (rank : 228)	θ value	6.43352e-06 (rank : 96)
Query Neighborhood Hits	207	Target Neighborhood Hits	1192	Shared Neighborhood Hits	149
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TIE2_MOUSE
NC score	0.228829 (rank : 229)	θ value	2.21117e-06 (rank : 88)
Query Neighborhood Hits	207	Target Neighborhood Hits	1204	Shared Neighborhood Hits	147
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

MFA3L_MOUSE
NC score	0.226620 (rank : 230)	θ value	θ > 10 (rank : 604)
Query Neighborhood Hits	207	Target Neighborhood Hits	214	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D3X9, Q80TV6, Q8BJA9	Gene names	Mfap3l, Kiaa0626
Domain Architecture	No domain graphic available
Description	Microfibrillar-associated protein 3-like precursor.

UFO_MOUSE
NC score	0.226436 (rank : 231)	θ value	0.0431538 (rank : 147)
Query Neighborhood Hits	207	Target Neighborhood Hits	988	Shared Neighborhood Hits	138
SwissProt Accessions	Q00993	Gene names	Axl, Ark, Ufo
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (Adhesion-related kinase).

EPHB2_MOUSE
NC score	0.223263 (rank : 232)	θ value	0.0113563 (rank : 135)
Query Neighborhood Hits	207	Target Neighborhood Hits	982	Shared Neighborhood Hits	139
SwissProt Accessions	P54763, Q62213, Q9QVY4	Gene names	Ephb2, Epth3, Nuk, Sek3
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (Neural kinase) (Nuk receptor tyrosine kinase) (SEK-3).

EPHB2_HUMAN
NC score	0.223204 (rank : 233)	θ value	0.0113563 (rank : 134)
Query Neighborhood Hits	207	Target Neighborhood Hits	983	Shared Neighborhood Hits	139
SwissProt Accessions	P29323, O43477, Q5T0U6, Q5T0U7, Q5T0U8	Gene names	EPHB2, DRT, EPTH3, ERK, HEK5
Domain Architecture
Description	Ephrin type-B receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-3) (DRT) (Receptor protein-tyrosine kinase HEK5) (ERK) (NY-REN-47 antigen).

VGFR2_HUMAN
NC score	0.220830 (rank : 234)	θ value	θ > 10 (rank : 871)
Query Neighborhood Hits	207	Target Neighborhood Hits	1103	Shared Neighborhood Hits	116
SwissProt Accessions	P35968, O60723, Q14178	Gene names	KDR, FLK1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Kinase insert domain receptor) (Protein-tyrosine kinase receptor Flk-1) (CD309 antigen).

UFO_HUMAN
NC score	0.220673 (rank : 235)	θ value	0.0961366 (rank : 154)
Query Neighborhood Hits	207	Target Neighborhood Hits	981	Shared Neighborhood Hits	136
SwissProt Accessions	P30530	Gene names	AXL, UFO
Domain Architecture
Description	Tyrosine-protein kinase receptor UFO precursor (EC 2.7.10.1) (AXL oncogene).

VSIG4_HUMAN
NC score	0.220224 (rank : 236)	θ value	θ > 10 (rank : 879)
Query Neighborhood Hits	207	Target Neighborhood Hits	236	Shared Neighborhood Hits	64
SwissProt Accessions	Q9Y279, Q6UXI4	Gene names	VSIG4, Z39IG
Domain Architecture	No domain graphic available
Description	V-set and immunoglobulin domain-containing protein 4 precursor (Protein Z39Ig).

DUET_HUMAN
NC score	0.220177 (rank : 237)	θ value	8.11959e-09 (rank : 56)
Query Neighborhood Hits	207	Target Neighborhood Hits	1220	Shared Neighborhood Hits	138
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

VGFR2_MOUSE
NC score	0.219741 (rank : 238)	θ value	θ > 10 (rank : 872)
Query Neighborhood Hits	207	Target Neighborhood Hits	1089	Shared Neighborhood Hits	116
SwissProt Accessions	P35918	Gene names	Kdr, Flk-1, Flk1
Domain Architecture
Description	Vascular endothelial growth factor receptor 2 precursor (EC 2.7.10.1) (VEGFR-2) (Protein-tyrosine kinase receptor flk-1) (Fetal liver kinase 1) (Kinase NYK) (CD309 antigen).

EPHA2_HUMAN
NC score	0.218930 (rank : 239)	θ value	1.06045e-08 (rank : 59)
Query Neighborhood Hits	207	Target Neighborhood Hits	1021	Shared Neighborhood Hits	134
SwissProt Accessions	P29317	Gene names	EPHA2, ECK
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase).

EPHA6_HUMAN
NC score	0.217781 (rank : 240)	θ value	0.0113563 (rank : 132)
Query Neighborhood Hits	207	Target Neighborhood Hits	959	Shared Neighborhood Hits	127
SwissProt Accessions	Q9UF33	Gene names	EPHA6, EHK2
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

ATL3_HUMAN
NC score	0.217289 (rank : 241)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	207	Target Neighborhood Hits	414	Shared Neighborhood Hits	80
SwissProt Accessions	P82987, Q9ULI7	Gene names	ADAMTSL3, KIAA1233
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 3 precursor (ADAMTSL-3) (Punctin-2).

RIMB2_HUMAN
NC score	0.216010 (rank : 242)	θ value	0.00298849 (rank : 127)
Query Neighborhood Hits	207	Target Neighborhood Hits	263	Shared Neighborhood Hits	59
SwissProt Accessions	O15034, Q96ID2	Gene names	RIMBP2, KIAA0318, RBP2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

ROS_HUMAN
NC score	0.215906 (rank : 243)	θ value	4.92598e-06 (rank : 93)
Query Neighborhood Hits	207	Target Neighborhood Hits	907	Shared Neighborhood Hits	150
SwissProt Accessions	P08922, Q15368	Gene names	ROS1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ROS precursor (EC 2.7.10.1) (c- ros-1).

EPHB1_HUMAN
NC score	0.215011 (rank : 244)	θ value	0.62314 (rank : 160)
Query Neighborhood Hits	207	Target Neighborhood Hits	988	Shared Neighborhood Hits	136
SwissProt Accessions	P54762, O43569, O95142, O95143	Gene names	EPHB1, EPHT2, NET
Domain Architecture
Description	Ephrin type-B receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH-2) (NET) (HEK6) (ELK).

CD166_MOUSE
NC score	0.214453 (rank : 245)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	207	Target Neighborhood Hits	252	Shared Neighborhood Hits	67
SwissProt Accessions	Q61490, O70136, Q8CDA5, Q8R2T0	Gene names	Alcam
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM) (DM-GRASP protein).

HCFC1_MOUSE
NC score	0.213871 (rank : 246)	θ value	0.000158464 (rank : 106)
Query Neighborhood Hits	207	Target Neighborhood Hits	348	Shared Neighborhood Hits	65
SwissProt Accessions	Q61191, Q684R1, Q7TSB0, Q8C2D0, Q9QWH2	Gene names	Hcfc1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N- terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

FGFR4_MOUSE
NC score	0.213738 (rank : 247)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	207	Target Neighborhood Hits	1026	Shared Neighborhood Hits	117
SwissProt Accessions	Q03142, Q5J7D9, Q8C3V5, Q8CIB8	Gene names	Fgfr4, Fgfr-4, Mpk-11
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (Protein-tyrosine kinase receptor MPK-11) (CD334 antigen).

EPHA2_MOUSE
NC score	0.212502 (rank : 248)	θ value	4.0297e-08 (rank : 64)
Query Neighborhood Hits	207	Target Neighborhood Hits	1020	Shared Neighborhood Hits	128
SwissProt Accessions	Q03145, Q60633, Q62212	Gene names	Epha2, Eck, Sek2
Domain Architecture
Description	Ephrin type-A receptor 2 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ECK) (Epithelial cell kinase) (MPK-5) (SEK-2).

ANKF1_HUMAN
NC score	0.211073 (rank : 249)	θ value	0.0736092 (rank : 150)
Query Neighborhood Hits	207	Target Neighborhood Hits	126	Shared Neighborhood Hits	42
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

FGFR4_HUMAN
NC score	0.210202 (rank : 250)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	207	Target Neighborhood Hits	1037	Shared Neighborhood Hits	117
SwissProt Accessions	P22455, O43785, Q14309	Gene names	FGFR4, JTK2, TKF
Domain Architecture
Description	Fibroblast growth factor receptor 4 precursor (EC 2.7.10.1) (FGFR-4) (CD334 antigen).

PTPRO_HUMAN
NC score	0.208955 (rank : 251)	θ value	θ > 10 (rank : 741)
Query Neighborhood Hits	207	Target Neighborhood Hits	139	Shared Neighborhood Hits	58
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

FGFR3_MOUSE
NC score	0.208849 (rank : 252)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	207	Target Neighborhood Hits	1059	Shared Neighborhood Hits	118
SwissProt Accessions	Q61851, Q61564, Q63834	Gene names	Fgfr3, Mfr3, Sam3
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (Heparin-binding growth factor receptor) (CD333 antigen).

EPHA6_MOUSE
NC score	0.208800 (rank : 253)	θ value	0.0113563 (rank : 133)
Query Neighborhood Hits	207	Target Neighborhood Hits	946	Shared Neighborhood Hits	117
SwissProt Accessions	Q62413, Q8CCN2	Gene names	Epha6, Ehk-2, Ehk2
Domain Architecture
Description	Ephrin type-A receptor 6 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-2) (EPH homology kinase 2).

EPHAA_HUMAN
NC score	0.206668 (rank : 254)	θ value	0.0252991 (rank : 139)
Query Neighborhood Hits	207	Target Neighborhood Hits	960	Shared Neighborhood Hits	118
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

FGFR1_MOUSE
NC score	0.206223 (rank : 255)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	207	Target Neighborhood Hits	1068	Shared Neighborhood Hits	116
SwissProt Accessions	P16092, Q01736, Q61562, Q80T10	Gene names	Fgfr1, Flg
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (MFR) (CD331 antigen).

FGFR1_HUMAN
NC score	0.206154 (rank : 256)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	207	Target Neighborhood Hits	1069	Shared Neighborhood Hits	116
SwissProt Accessions	P11362, P17049, Q02063, Q02065, Q14306, Q14307, Q8N685	Gene names	FGFR1, FGFBR, FLG, FLT2
Domain Architecture
Description	Basic fibroblast growth factor receptor 1 precursor (EC 2.7.10.1) (FGFR-1) (bFGF-R) (Fms-like tyrosine kinase 2) (c-fgr) (CD331 antigen).

FGFR2_HUMAN
NC score	0.204549 (rank : 257)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	207	Target Neighborhood Hits	1062	Shared Neighborhood Hits	116
SwissProt Accessions	P21802, P18443, Q01742, Q12922, Q14300, Q14301, Q14302, Q14303, Q14304, Q14305, Q14672, Q14718, Q14719, Q86YI4, Q96KL9, Q96KM0, Q96KM1, Q96KM2, Q9NZU2, Q9NZU3, Q9UD01, Q9UD02, Q9UIH3, Q9UIH4, Q9UIH5, Q9UIH6, Q9UIH7, Q9UIH8, Q9UM87, Q9UMC6, Q9UNS7, Q9UQH7, Q9UQH8, Q9UQH9, Q9UQI0	Gene names	FGFR2, BEK, KSAM
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor 2) (CD332 antigen).

FGFR3_HUMAN
NC score	0.203488 (rank : 258)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	207	Target Neighborhood Hits	1042	Shared Neighborhood Hits	116
SwissProt Accessions	P22607, Q14308, Q16294, Q16608	Gene names	FGFR3, JTK4
Domain Architecture
Description	Fibroblast growth factor receptor 3 precursor (EC 2.7.10.1) (FGFR-3) (CD333 antigen).

GPA33_MOUSE
NC score	0.203118 (rank : 259)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	207	Target Neighborhood Hits	294	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JKA5, Q922D5	Gene names	Gpa33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33) (mA33).

IL1R2_HUMAN
NC score	0.199416 (rank : 260)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	207	Target Neighborhood Hits	153	Shared Neighborhood Hits	54
SwissProt Accessions	P27930, Q9UE68	Gene names	IL1R2, IL1RB
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen) (CDw121b).

EPHA5_MOUSE
NC score	0.198792 (rank : 261)	θ value	0.000461057 (rank : 112)
Query Neighborhood Hits	207	Target Neighborhood Hits	950	Shared Neighborhood Hits	137
SwissProt Accessions	Q60629	Gene names	Epha5, Bsk, Cek7, Ehk1
Domain Architecture
Description	Ephrin type-A receptor 5 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EHK-1) (EPH homology kinase 1) (Brain-specific kinase) (CEK-7).

FGFR2_MOUSE
NC score	0.197777 (rank : 262)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	207	Target Neighborhood Hits	1062	Shared Neighborhood Hits	116
SwissProt Accessions	P21803, O55141, Q00389, Q61342	Gene names	Fgfr2, Bek, Ect1
Domain Architecture
Description	Fibroblast growth factor receptor 2 precursor (EC 2.7.10.1) (FGFR-2) (Keratinocyte growth factor receptor) (CD332 antigen).

CILP2_HUMAN
NC score	0.197628 (rank : 263)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	207	Target Neighborhood Hits	307	Shared Neighborhood Hits	74
SwissProt Accessions	Q8IUL8, Q6NV88, Q8N4A6, Q8WV21	Gene names	CILP2
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 2 precursor (CILP-2) [Contains: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2].

GPA33_HUMAN
NC score	0.197234 (rank : 264)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	207	Target Neighborhood Hits	273	Shared Neighborhood Hits	59
SwissProt Accessions	Q99795	Gene names	GPA33
Domain Architecture
Description	Cell surface A33 antigen precursor (Glycoprotein A33).

NRG1_HUMAN
NC score	0.197172 (rank : 265)	θ value	θ > 10 (rank : 647)
Query Neighborhood Hits	207	Target Neighborhood Hits	285	Shared Neighborhood Hits	68
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

SIGL5_MOUSE
NC score	0.196459 (rank : 266)	θ value	θ > 10 (rank : 785)
Query Neighborhood Hits	207	Target Neighborhood Hits	271	Shared Neighborhood Hits	67
SwissProt Accessions	Q920G3	Gene names	Siglec5, Siglecf
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Sialic acid-binding Ig-like lectin-F) (mSiglec-F).

CEAM6_HUMAN
NC score	0.195543 (rank : 267)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	207	Target Neighborhood Hits	308	Shared Neighborhood Hits	75
SwissProt Accessions	P40199, Q14920	Gene names	CEACAM6, NCA
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 6 precursor (Normal cross-reacting antigen) (Nonspecific crossreacting antigen) (CD66c antigen).

ROR2_MOUSE
NC score	0.195382 (rank : 268)	θ value	θ > 10 (rank : 776)
Query Neighborhood Hits	207	Target Neighborhood Hits	1000	Shared Neighborhood Hits	119
SwissProt Accessions	Q9Z138	Gene names	Ror2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2) (mROR2).

CD166_HUMAN
NC score	0.195160 (rank : 269)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	207	Target Neighborhood Hits	247	Shared Neighborhood Hits	64
SwissProt Accessions	Q13740, O60892	Gene names	ALCAM, MEMD
Domain Architecture
Description	CD166 antigen precursor (Activated leukocyte-cell adhesion molecule) (ALCAM).

ROR2_HUMAN
NC score	0.190376 (rank : 270)	θ value	θ > 10 (rank : 775)
Query Neighborhood Hits	207	Target Neighborhood Hits	1014	Shared Neighborhood Hits	118
SwissProt Accessions	Q01974, Q59GF5, Q5SPI5, Q9HAY7, Q9HB61	Gene names	ROR2, NTRKR2
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR2 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2).

VGFR3_HUMAN
NC score	0.188079 (rank : 271)	θ value	θ > 10 (rank : 873)
Query Neighborhood Hits	207	Target Neighborhood Hits	1037	Shared Neighborhood Hits	116
SwissProt Accessions	P35916	Gene names	FLT4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

LRFN4_HUMAN
NC score	0.187744 (rank : 272)	θ value	θ > 10 (rank : 547)
Query Neighborhood Hits	207	Target Neighborhood Hits	462	Shared Neighborhood Hits	91
SwissProt Accessions	Q6PJG9, Q9BWJ0	Gene names	LRFN4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

CD45_HUMAN
NC score	0.187420 (rank : 273)	θ value	4.03905 (rank : 177)
Query Neighborhood Hits	207	Target Neighborhood Hits	243	Shared Neighborhood Hits	58
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

HCFC1_HUMAN
NC score	0.186573 (rank : 274)	θ value	0.000786445 (rank : 116)
Query Neighborhood Hits	207	Target Neighborhood Hits	331	Shared Neighborhood Hits	52
SwissProt Accessions	P51610, Q6P4G5	Gene names	HCFC1, HCF1
Domain Architecture	No domain graphic available
Description	Host cell factor (HCF) (HCF-1) (C1 factor) (VP16 accessory protein) (VCAF) (CFF) [Contains: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C- terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6].

VGFR3_MOUSE
NC score	0.186428 (rank : 275)	θ value	θ > 10 (rank : 874)
Query Neighborhood Hits	207	Target Neighborhood Hits	1056	Shared Neighborhood Hits	117
SwissProt Accessions	P35917	Gene names	Flt4, Flt-4
Domain Architecture
Description	Vascular endothelial growth factor receptor 3 precursor (EC 2.7.10.1) (VEGFR-3) (Tyrosine-protein kinase receptor FLT4).

ROR1_HUMAN
NC score	0.184026 (rank : 276)	θ value	θ > 10 (rank : 773)
Query Neighborhood Hits	207	Target Neighborhood Hits	1018	Shared Neighborhood Hits	116
SwissProt Accessions	Q01973, Q92776	Gene names	ROR1, NTRKR1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1).

ROR1_MOUSE
NC score	0.182642 (rank : 277)	θ value	θ > 10 (rank : 774)
Query Neighborhood Hits	207	Target Neighborhood Hits	1025	Shared Neighborhood Hits	117
SwissProt Accessions	Q9Z139	Gene names	Ror1, Ntrkr1
Domain Architecture
Description	Tyrosine-protein kinase transmembrane receptor ROR1 precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 1) (mROR1).

LRFN4_MOUSE
NC score	0.181606 (rank : 278)	θ value	θ > 10 (rank : 548)
Query Neighborhood Hits	207	Target Neighborhood Hits	442	Shared Neighborhood Hits	86
SwissProt Accessions	Q80XU8, Q3TQG8, Q8K3C4	Gene names	Lrfn4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 precursor.

CRLF1_HUMAN
NC score	0.181439 (rank : 279)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	207	Target Neighborhood Hits	122	Shared Neighborhood Hits	78
SwissProt Accessions	O75462, Q9UHH5	Gene names	CRLF1, ZCYTOR5
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (ZcytoR5).

EPHA1_MOUSE
NC score	0.180352 (rank : 280)	θ value	0.00298849 (rank : 126)
Query Neighborhood Hits	207	Target Neighborhood Hits	958	Shared Neighborhood Hits	111
SwissProt Accessions	Q60750, Q8CED9, Q9ESJ2	Gene names	Epha1, Esk
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor ESK).

EPHA1_HUMAN
NC score	0.179690 (rank : 281)	θ value	0.00035302 (rank : 109)
Query Neighborhood Hits	207	Target Neighborhood Hits	997	Shared Neighborhood Hits	104
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

CRLF1_MOUSE
NC score	0.178662 (rank : 282)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	207	Target Neighborhood Hits	116	Shared Neighborhood Hits	74
SwissProt Accessions	Q9JM58	Gene names	Crlf1, Crlm3
Domain Architecture
Description	Cytokine receptor-like factor 1 precursor (Cytokine-like factor 1) (CLF-1) (Cytokine receptor-like molecule 3) (CRLM-3) (NR6).

IL27B_HUMAN
NC score	0.178632 (rank : 283)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	207	Target Neighborhood Hits	80	Shared Neighborhood Hits	57
SwissProt Accessions	Q14213, O75269	Gene names	EBI3, IL27B
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein) (EBV-induced gene 3 protein).

RIMB2_MOUSE
NC score	0.178130 (rank : 284)	θ value	θ > 10 (rank : 759)
Query Neighborhood Hits	207	Target Neighborhood Hits	246	Shared Neighborhood Hits	52
SwissProt Accessions	Q80U40	Gene names	Rimbp2, Kiaa0318, Rbp2
Domain Architecture
Description	RIM-binding protein 2 (RIM-BP2).

LRFN2_MOUSE
NC score	0.177196 (rank : 285)	θ value	θ > 10 (rank : 544)
Query Neighborhood Hits	207	Target Neighborhood Hits	450	Shared Neighborhood Hits	84
SwissProt Accessions	Q80TG9, Q9CYK3	Gene names	Lrfn2, Kiaa1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

LRC21_MOUSE
NC score	0.176520 (rank : 286)	θ value	θ > 10 (rank : 538)
Query Neighborhood Hits	207	Target Neighborhood Hits	462	Shared Neighborhood Hits	97
SwissProt Accessions	Q8K099, Q8BXN3	Gene names	Lrrc21, Pal
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

NTRK2_HUMAN
NC score	0.176206 (rank : 287)	θ value	θ > 10 (rank : 653)
Query Neighborhood Hits	207	Target Neighborhood Hits	1081	Shared Neighborhood Hits	117
SwissProt Accessions	Q16620, Q16675, Q8WXJ6	Gene names	NTRK2, TRKB
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB) (Trk-B).

NTRK2_MOUSE
NC score	0.175636 (rank : 288)	θ value	θ > 10 (rank : 654)
Query Neighborhood Hits	207	Target Neighborhood Hits	1088	Shared Neighborhood Hits	118
SwissProt Accessions	P15209, Q3TUF9, Q80WU0, Q91XJ9	Gene names	Ntrk2, Trkb
Domain Architecture
Description	BDNF/NT-3 growth factors receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase) (GP145-TrkB/GP95-TrkB) (Trk-B).

CD45_MOUSE
NC score	0.175447 (rank : 289)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	207	Target Neighborhood Hits	178	Shared Neighborhood Hits	46
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

UNC5D_MOUSE
NC score	0.175043 (rank : 290)	θ value	θ > 10 (rank : 866)
Query Neighborhood Hits	207	Target Neighborhood Hits	268	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K1S2	Gene names	Unc5d, Unc5h4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

LRFN2_HUMAN
NC score	0.175041 (rank : 291)	θ value	θ > 10 (rank : 543)
Query Neighborhood Hits	207	Target Neighborhood Hits	450	Shared Neighborhood Hits	82
SwissProt Accessions	Q9ULH4, Q5SYP9	Gene names	LRFN2, KIAA1246
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor.

NTRK3_HUMAN
NC score	0.174992 (rank : 292)	θ value	θ > 10 (rank : 655)
Query Neighborhood Hits	207	Target Neighborhood Hits	1115	Shared Neighborhood Hits	119
SwissProt Accessions	Q16288, Q12827, Q16289	Gene names	NTRK3, TRKC
Domain Architecture
Description	NT-3 growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase) (GP145-TrkC) (Trk-C).

CSF1R_MOUSE
NC score	0.174349 (rank : 293)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	207	Target Neighborhood Hits	983	Shared Neighborhood Hits	109
SwissProt Accessions	P09581, Q3U3P1, Q9DBH9	Gene names	Csf1r, Csfmr, Fms
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

LRFN3_MOUSE
NC score	0.173386 (rank : 294)	θ value	θ > 10 (rank : 546)
Query Neighborhood Hits	207	Target Neighborhood Hits	455	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BLY3	Gene names	Lrfn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

IRPL2_HUMAN
NC score	0.171514 (rank : 295)	θ value	θ > 10 (rank : 438)
Query Neighborhood Hits	207	Target Neighborhood Hits	194	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NP60, Q9NZN0	Gene names	IL1RAPL2, IL1R9
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (Interleukin-1 receptor 9) (IL-1R9) (IL-1 receptor accessory protein-like 2) (Three immunoglobulin domain- containing IL-1 receptor-related 1) (TIGIRR-1).

PSG3_HUMAN
NC score	0.171245 (rank : 296)	θ value	θ > 10 (rank : 691)
Query Neighborhood Hits	207	Target Neighborhood Hits	242	Shared Neighborhood Hits	69
SwissProt Accessions	Q16557, Q08265, Q9BRW2, Q9UPL4, Q9UQ77	Gene names	PSG3
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 3 precursor (PSBG-3) (Carcinoembryonic antigen SG5).

INSRR_HUMAN
NC score	0.170428 (rank : 297)	θ value	0.0252991 (rank : 141)
Query Neighborhood Hits	207	Target Neighborhood Hits	950	Shared Neighborhood Hits	104
SwissProt Accessions	P14616, O60724	Gene names	INSRR, IRR
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

IRPL2_MOUSE
NC score	0.169874 (rank : 298)	θ value	θ > 10 (rank : 439)
Query Neighborhood Hits	207	Target Neighborhood Hits	195	Shared Neighborhood Hits	63
SwissProt Accessions	Q9ERS6, Q9ER66	Gene names	Il1rapl2
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 2 precursor (IL1RAPL-2-related protein) (TIGIRR-1).

I12R1_HUMAN
NC score	0.169854 (rank : 299)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	207	Target Neighborhood Hits	78	Shared Neighborhood Hits	59
SwissProt Accessions	P42701	Gene names	IL12RB1, IL12R, IL12RB
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (IL- 12RB1) (CD212 antigen).

UNC5D_HUMAN
NC score	0.169754 (rank : 300)	θ value	θ > 10 (rank : 865)
Query Neighborhood Hits	207	Target Neighborhood Hits	267	Shared Neighborhood Hits	73
SwissProt Accessions	Q6UXZ4, Q8WYP7	Gene names	UNC5D, KIAA1777, UNC5H4
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5D precursor (Unc-5 homolog D) (Unc-5 homolog 4).

LRC21_HUMAN
NC score	0.169653 (rank : 301)	θ value	θ > 10 (rank : 537)
Query Neighborhood Hits	207	Target Neighborhood Hits	456	Shared Neighborhood Hits	93
SwissProt Accessions	Q9P2V4, Q9Y4N7	Gene names	LRRC21, PAL
Domain Architecture
Description	Leucine-rich repeat-containing protein 21 precursor (Photoreceptor- associated LRR superfamily protein) (Retina-specific protein PAL).

INSRR_MOUSE
NC score	0.168985 (rank : 302)	θ value	0.0431538 (rank : 144)
Query Neighborhood Hits	207	Target Neighborhood Hits	961	Shared Neighborhood Hits	103
SwissProt Accessions	Q9WTL4	Gene names	Insrr, Irr
Domain Architecture
Description	Insulin receptor-related protein precursor (EC 2.7.10.1) (IRR) (IR- related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain].

PGFRA_HUMAN
NC score	0.168783 (rank : 303)	θ value	θ > 10 (rank : 674)
Query Neighborhood Hits	207	Target Neighborhood Hits	980	Shared Neighborhood Hits	110
SwissProt Accessions	P16234, Q96KZ7	Gene names	PDGFRA
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PGFRA_MOUSE
NC score	0.167614 (rank : 304)	θ value	θ > 10 (rank : 675)
Query Neighborhood Hits	207	Target Neighborhood Hits	975	Shared Neighborhood Hits	109
SwissProt Accessions	P26618, Q62046	Gene names	Pdgfra
Domain Architecture
Description	Alpha platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-alpha) (CD140a antigen).

PSG8_HUMAN
NC score	0.167176 (rank : 305)	θ value	θ > 10 (rank : 696)
Query Neighborhood Hits	207	Target Neighborhood Hits	239	Shared Neighborhood Hits	67
SwissProt Accessions	Q9UQ74, O60410	Gene names	PSG8
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 8 precursor (PSBG-8).

CEAM8_HUMAN
NC score	0.167067 (rank : 306)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	207	Target Neighborhood Hits	264	Shared Neighborhood Hits	72
SwissProt Accessions	P31997, O60399, Q16574	Gene names	CEACAM8, CGM6
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 8 precursor (Carcinoembryonic antigen CGM6) (Nonspecific cross-reacting antigen NCA-95) (CD67 antigen) (CD66b antigen).

PSG4_HUMAN
NC score	0.165784 (rank : 307)	θ value	θ > 10 (rank : 692)
Query Neighborhood Hits	207	Target Neighborhood Hits	243	Shared Neighborhood Hits	64
SwissProt Accessions	Q00888, Q13047, Q13048, Q15234, Q15240, Q9UQ76	Gene names	PSG4, CGM4, PSG9
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 4 precursor (PSBG-4) (PSBG-9).

IGF1R_HUMAN
NC score	0.165644 (rank : 308)	θ value	0.0148317 (rank : 136)
Query Neighborhood Hits	207	Target Neighborhood Hits	977	Shared Neighborhood Hits	104
SwissProt Accessions	P08069	Gene names	IGF1R
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

LRFN3_HUMAN
NC score	0.164615 (rank : 309)	θ value	θ > 10 (rank : 545)
Query Neighborhood Hits	207	Target Neighborhood Hits	444	Shared Neighborhood Hits	88
SwissProt Accessions	Q9BTN0, Q6UY10	Gene names	LRFN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 precursor.

EMB_MOUSE
NC score	0.164600 (rank : 310)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	207	Target Neighborhood Hits	83	Shared Neighborhood Hits	39
SwissProt Accessions	P21995, Q3UFF1, Q8C2J8, Q8C543, Q96C38	Gene names	Emb, Gp70
Domain Architecture
Description	Embigin precursor (Teratocarcinoma glycoprotein Gp-70).

INSR_MOUSE
NC score	0.164573 (rank : 311)	θ value	0.21417 (rank : 156)
Query Neighborhood Hits	207	Target Neighborhood Hits	968	Shared Neighborhood Hits	107
SwissProt Accessions	P15208	Gene names	Insr
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

IGF1R_MOUSE
NC score	0.163400 (rank : 312)	θ value	0.0330416 (rank : 143)
Query Neighborhood Hits	207	Target Neighborhood Hits	973	Shared Neighborhood Hits	103
SwissProt Accessions	Q60751, O70438, Q62123	Gene names	Igf1r
Domain Architecture
Description	Insulin-like growth factor 1 receptor precursor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD221 antigen) [Contains: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain].

IL1R2_MOUSE
NC score	0.162580 (rank : 313)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	207	Target Neighborhood Hits	125	Shared Neighborhood Hits	48
SwissProt Accessions	P27931	Gene names	Il1r2, Il-1r2, Il1rb
Domain Architecture
Description	Interleukin-1 receptor type II precursor (IL-1R-2) (IL-1R-beta) (CD121b antigen).

IRPL1_MOUSE
NC score	0.161512 (rank : 314)	θ value	θ > 10 (rank : 437)
Query Neighborhood Hits	207	Target Neighborhood Hits	186	Shared Neighborhood Hits	64
SwissProt Accessions	P59823	Gene names	Il1rapl1
Domain Architecture	No domain graphic available
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1).

UNC5A_HUMAN
NC score	0.160568 (rank : 315)	θ value	θ > 10 (rank : 859)
Query Neighborhood Hits	207	Target Neighborhood Hits	198	Shared Neighborhood Hits	64
SwissProt Accessions	Q6ZN44, Q8TF26, Q96GP4	Gene names	UNC5A, KIAA1976, UNC5H1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

KIT_MOUSE
NC score	0.160080 (rank : 316)	θ value	θ > 10 (rank : 484)
Query Neighborhood Hits	207	Target Neighborhood Hits	949	Shared Neighborhood Hits	108
SwissProt Accessions	P05532, Q61415, Q61416, Q61417, Q6LEE9	Gene names	Kit, Sl
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

INSR_HUMAN
NC score	0.159961 (rank : 317)	θ value	0.279714 (rank : 157)
Query Neighborhood Hits	207	Target Neighborhood Hits	963	Shared Neighborhood Hits	103
SwissProt Accessions	P06213	Gene names	INSR
Domain Architecture
Description	Insulin receptor precursor (EC 2.7.10.1) (IR) (CD220 antigen) [Contains: Insulin receptor subunit alpha; Insulin receptor subunit beta].

ESAM_HUMAN
NC score	0.159805 (rank : 318)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	207	Target Neighborhood Hits	251	Shared Neighborhood Hits	57
SwissProt Accessions	Q96AP7, Q96T50	Gene names	ESAM
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

CXAR_HUMAN
NC score	0.159286 (rank : 319)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	207	Target Neighborhood Hits	245	Shared Neighborhood Hits	54
SwissProt Accessions	P78310, O00694, Q8WWT6, Q8WWT7, Q8WWT8, Q9UKV4	Gene names	CXADR, CAR
Domain Architecture
Description	Coxsackievirus and adenovirus receptor precursor (Coxsackievirus B- adenovirus receptor) (hCAR) (CVB3-binding protein) (HCVADR).

LRFN5_MOUSE
NC score	0.159105 (rank : 320)	θ value	θ > 10 (rank : 550)
Query Neighborhood Hits	207	Target Neighborhood Hits	472	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

PSG7_HUMAN
NC score	0.158984 (rank : 321)	θ value	θ > 10 (rank : 695)
Query Neighborhood Hits	207	Target Neighborhood Hits	239	Shared Neighborhood Hits	64
SwissProt Accessions	Q13046, Q15232	Gene names	PSG7
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 7 precursor (PSBG-7).

I12R1_MOUSE
NC score	0.158386 (rank : 322)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	207	Target Neighborhood Hits	70	Shared Neighborhood Hits	51
SwissProt Accessions	Q60837	Gene names	Il12rb1, Il12rb
Domain Architecture
Description	Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component) (CD212 antigen).

PGFRB_MOUSE
NC score	0.157351 (rank : 323)	θ value	θ > 10 (rank : 677)
Query Neighborhood Hits	207	Target Neighborhood Hits	960	Shared Neighborhood Hits	104
SwissProt Accessions	P05622	Gene names	Pdgfrb, Pdgfr
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PSG1_HUMAN
NC score	0.157126 (rank : 324)	θ value	θ > 10 (rank : 689)
Query Neighborhood Hits	207	Target Neighborhood Hits	232	Shared Neighborhood Hits	65
SwissProt Accessions	P11464, O75236, P11462, P11463, Q15231, Q15241, Q15243, Q16660, Q9P1W5, Q9UQ79	Gene names	PSG1, B1G1, PSGGA
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 1 precursor (PSBG-1) (Pregnancy-specific beta-1 glycoprotein C/D) (PS-beta-C/D) (Fetal liver non-specific cross-reactive antigen 1/2) (FL-NCA-1/2) (PSG95) (CD66f antigen).

PTPRG_HUMAN
NC score	0.156818 (rank : 325)	θ value	θ > 10 (rank : 737)
Query Neighborhood Hits	207	Target Neighborhood Hits	231	Shared Neighborhood Hits	54
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

CT075_HUMAN
NC score	0.155731 (rank : 326)	θ value	3.0926 (rank : 174)
Query Neighborhood Hits	207	Target Neighborhood Hits	387	Shared Neighborhood Hits	75
SwissProt Accessions	Q8WUT4, Q5JWV6, Q9H419	Gene names	C20orf75
Domain Architecture
Description	Uncharacterized protein C20orf75 precursor.

LRFN5_HUMAN
NC score	0.155286 (rank : 327)	θ value	θ > 10 (rank : 549)
Query Neighborhood Hits	207	Target Neighborhood Hits	464	Shared Neighborhood Hits	80
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

PTPRG_MOUSE
NC score	0.154987 (rank : 328)	θ value	θ > 10 (rank : 738)
Query Neighborhood Hits	207	Target Neighborhood Hits	260	Shared Neighborhood Hits	52
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PSG11_HUMAN
NC score	0.154813 (rank : 329)	θ value	θ > 10 (rank : 688)
Query Neighborhood Hits	207	Target Neighborhood Hits	223	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UQ72, Q13179, Q15242, Q9UNE4	Gene names	PSG11, PSG13
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 11 precursor (PSBG-11) (PSBG- 13).

MOX2R_MOUSE
NC score	0.154386 (rank : 330)	θ value	θ > 10 (rank : 615)
Query Neighborhood Hits	207	Target Neighborhood Hits	110	Shared Neighborhood Hits	40
SwissProt Accessions	Q9ES57	Gene names	Cd200r1, Mox2r, Ox2r
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

PTPRE_MOUSE
NC score	0.153390 (rank : 331)	θ value	θ > 10 (rank : 736)
Query Neighborhood Hits	207	Target Neighborhood Hits	86	Shared Neighborhood Hits	15
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

CILP1_HUMAN
NC score	0.153083 (rank : 332)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	207	Target Neighborhood Hits	266	Shared Neighborhood Hits	75
SwissProt Accessions	O75339, Q6UW99, Q8IYI5	Gene names	CILP
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) (Cartilage intermediate-layer protein) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

PTPRE_HUMAN
NC score	0.152998 (rank : 333)	θ value	θ > 10 (rank : 735)
Query Neighborhood Hits	207	Target Neighborhood Hits	92	Shared Neighborhood Hits	15
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_HUMAN
NC score	0.152886 (rank : 334)	θ value	θ > 10 (rank : 733)
Query Neighborhood Hits	207	Target Neighborhood Hits	101	Shared Neighborhood Hits	16
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

IRPL1_HUMAN
NC score	0.152770 (rank : 335)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	207	Target Neighborhood Hits	196	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NZN1, Q9UJ53	Gene names	IL1RAPL1, OPHN4
Domain Architecture
Description	X-linked interleukin-1 receptor accessory protein-like 1 precursor (IL1RAPL-1) (Oligophrenin-4) (Three immunoglobulin domain-containing IL-1 receptor-related 2) (TIGIRR-2).

PTPRA_MOUSE
NC score	0.152486 (rank : 336)	θ value	θ > 10 (rank : 734)
Query Neighborhood Hits	207	Target Neighborhood Hits	93	Shared Neighborhood Hits	15
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRZ_HUMAN
NC score	0.152415 (rank : 337)	θ value	θ > 10 (rank : 745)
Query Neighborhood Hits	207	Target Neighborhood Hits	255	Shared Neighborhood Hits	40
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

SIGL8_HUMAN
NC score	0.152067 (rank : 338)	θ value	θ > 10 (rank : 788)
Query Neighborhood Hits	207	Target Neighborhood Hits	252	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NYZ4, Q7Z728	Gene names	SIGLEC8, SAF2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 8 precursor (Siglec-8) (Sialoadhesin family member 2) (SAF-2) (CDw329 antigen).

CD276_HUMAN
NC score	0.151795 (rank : 339)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	207	Target Neighborhood Hits	261	Shared Neighborhood Hits	43
SwissProt Accessions	Q5ZPR3, Q6P5Y4, Q6UXI2, Q8NBI8, Q8NC34, Q8NCB6, Q9BXR1	Gene names	CD276, B7H3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3) (4Ig-B7-H3).

PSG6_HUMAN
NC score	0.151716 (rank : 340)	θ value	θ > 10 (rank : 694)
Query Neighborhood Hits	207	Target Neighborhood Hits	231	Shared Neighborhood Hits	62
SwissProt Accessions	Q00889	Gene names	PSG6, CGM3, PSGGB
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 6 precursor (PSBG-6).

PIGR_HUMAN
NC score	0.151054 (rank : 341)	θ value	θ > 10 (rank : 680)
Query Neighborhood Hits	207	Target Neighborhood Hits	164	Shared Neighborhood Hits	47
SwissProt Accessions	P01833, Q8IZY7	Gene names	PIGR
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) (Hepatocellular carcinoma-associated protein TB6) [Contains: Secretory component].

KIT_HUMAN
NC score	0.150965 (rank : 342)	θ value	θ > 10 (rank : 483)
Query Neighborhood Hits	207	Target Neighborhood Hits	953	Shared Neighborhood Hits	107
SwissProt Accessions	P10721, Q9UM99	Gene names	KIT
Domain Architecture
Description	Mast/stem cell growth factor receptor precursor (EC 2.7.10.1) (SCFR) (Proto-oncogene tyrosine-protein kinase Kit) (c-kit) (CD117 antigen).

SIGL5_HUMAN
NC score	0.150818 (rank : 343)	θ value	θ > 10 (rank : 784)
Query Neighborhood Hits	207	Target Neighborhood Hits	246	Shared Neighborhood Hits	66
SwissProt Accessions	O15389	Gene names	SIGLEC5, CD33L2, OBBP2
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 5 precursor (Siglec-5) (Obesity- binding protein 2) (OB-binding protein 2) (OB-BP2) (CD33 antigen-like 2) (CD170 antigen).

PIGR_MOUSE
NC score	0.150720 (rank : 344)	θ value	θ > 10 (rank : 681)
Query Neighborhood Hits	207	Target Neighborhood Hits	214	Shared Neighborhood Hits	47
SwissProt Accessions	O70570	Gene names	Pigr
Domain Architecture
Description	Polymeric-immunoglobulin receptor precursor (Poly-Ig receptor) (PIGR) [Contains: Secretory component].

PGFRB_HUMAN
NC score	0.150221 (rank : 345)	θ value	θ > 10 (rank : 676)
Query Neighborhood Hits	207	Target Neighborhood Hits	962	Shared Neighborhood Hits	109
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

LRRN1_HUMAN
NC score	0.150190 (rank : 346)	θ value	θ > 10 (rank : 565)
Query Neighborhood Hits	207	Target Neighborhood Hits	518	Shared Neighborhood Hits	97
SwissProt Accessions	Q6UXK5, Q3LID5, Q8IYV5, Q9H8V1, Q9P231	Gene names	LRRN1, KIAA1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

CILP1_MOUSE
NC score	0.150149 (rank : 347)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	207	Target Neighborhood Hits	282	Shared Neighborhood Hits	71
SwissProt Accessions	Q66K08, Q7TSS0, Q7TSS1, Q8BV01	Gene names	Cilp
Domain Architecture	No domain graphic available
Description	Cartilage intermediate layer protein 1 precursor (CILP-1) [Contains: Cartilage intermediate layer protein 1 C1; Cartilage intermediate layer protein 1 C2].

PSG10_HUMAN
NC score	0.149359 (rank : 348)	θ value	θ > 10 (rank : 687)
Query Neighborhood Hits	207	Target Neighborhood Hits	227	Shared Neighborhood Hits	62
SwissProt Accessions	Q15235, O75244, Q15224	Gene names	PSG10, PSG12
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 10 precursor (PSBG-10) (PSBG- 12).

UNC5C_MOUSE
NC score	0.149192 (rank : 349)	θ value	θ > 10 (rank : 864)
Query Neighborhood Hits	207	Target Neighborhood Hits	225	Shared Neighborhood Hits	67
SwissProt Accessions	O08747, Q8CD16	Gene names	Unc5c, Rcm, Unc5h3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3) (Rostral cerebellar malformation protein).

PSG2_HUMAN
NC score	0.149077 (rank : 350)	θ value	θ > 10 (rank : 690)
Query Neighborhood Hits	207	Target Neighborhood Hits	229	Shared Neighborhood Hits	64
SwissProt Accessions	P11465, Q8TCD9, Q9UEA4, Q9UQ78	Gene names	PSG2
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 2 precursor (PSBG-2) (Pregnancy-specific beta-1 glycoprotein E) (PS-beta-E).

UNC5C_HUMAN
NC score	0.148483 (rank : 351)	θ value	θ > 10 (rank : 863)
Query Neighborhood Hits	207	Target Neighborhood Hits	226	Shared Neighborhood Hits	66
SwissProt Accessions	O95185, Q8IUT0	Gene names	UNC5C, UNC5H3
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5C precursor (Unc-5 homolog C) (Unc-5 homolog 3).

CXAR_MOUSE
NC score	0.146989 (rank : 352)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	207	Target Neighborhood Hits	250	Shared Neighborhood Hits	54
SwissProt Accessions	P97792, O09052, Q3ULD0, Q91W66, Q99KG0, Q9DBJ8	Gene names	Cxadr, Car
Domain Architecture
Description	Coxsackievirus and adenovirus receptor homolog precursor (CAR) (mCAR).

ESAM_MOUSE
NC score	0.146887 (rank : 353)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	207	Target Neighborhood Hits	222	Shared Neighborhood Hits	57
SwissProt Accessions	Q925F2	Gene names	Esam, Esam1
Domain Architecture	No domain graphic available
Description	Endothelial cell-selective adhesion molecule precursor.

LRRN3_HUMAN
NC score	0.145640 (rank : 354)	θ value	θ > 10 (rank : 567)
Query Neighborhood Hits	207	Target Neighborhood Hits	461	Shared Neighborhood Hits	90
SwissProt Accessions	Q9H3W5, O43377, Q6I9V8, Q8IYQ6	Gene names	LRRN3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

TRIM9_HUMAN
NC score	0.144005 (rank : 355)	θ value	0.000158464 (rank : 107)
Query Neighborhood Hits	207	Target Neighborhood Hits	294	Shared Neighborhood Hits	56
SwissProt Accessions	Q9C026, Q92557, Q96D24, Q96NI4, Q9C025, Q9C027	Gene names	TRIM9, KIAA0282, RNF91
Domain Architecture
Description	Tripartite motif-containing protein 9 (RING finger protein 91).

LRRN1_MOUSE
NC score	0.143710 (rank : 356)	θ value	θ > 10 (rank : 566)
Query Neighborhood Hits	207	Target Neighborhood Hits	508	Shared Neighborhood Hits	94
SwissProt Accessions	Q61809, Q3USY1, Q69ZI0	Gene names	Lrrn1, Kiaa1497
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 1 precursor (Neuronal leucine- rich repeat protein 1) (NLRR-1).

UNC5B_HUMAN
NC score	0.142442 (rank : 357)	θ value	θ > 10 (rank : 861)
Query Neighborhood Hits	207	Target Neighborhood Hits	225	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

UNC5B_MOUSE
NC score	0.141223 (rank : 358)	θ value	θ > 10 (rank : 862)
Query Neighborhood Hits	207	Target Neighborhood Hits	226	Shared Neighborhood Hits	70
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

CSF1R_HUMAN
NC score	0.140805 (rank : 359)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	207	Target Neighborhood Hits	943	Shared Neighborhood Hits	101
SwissProt Accessions	P07333, Q6LDW5, Q6LDY4	Gene names	CSF1R, FMS
Domain Architecture
Description	Macrophage colony-stimulating factor 1 receptor precursor (EC 2.7.10.1) (CSF-1-R) (Fms proto-oncogene) (c-fms) (CD115 antigen).

TRIM9_MOUSE
NC score	0.140617 (rank : 360)	θ value	5.44631e-05 (rank : 102)
Query Neighborhood Hits	207	Target Neighborhood Hits	274	Shared Neighborhood Hits	53
SwissProt Accessions	Q8C7M3, Q6ZQE5, Q80WT6, Q8C7Z4, Q8CC32, Q8CEG2, Q99PQ3	Gene names	Trim9, Kiaa0282
Domain Architecture
Description	Tripartite motif-containing protein 9.

PSG9_HUMAN
NC score	0.140275 (rank : 361)	θ value	θ > 10 (rank : 697)
Query Neighborhood Hits	207	Target Neighborhood Hits	221	Shared Neighborhood Hits	61
SwissProt Accessions	Q00887, Q15236, Q15237, Q8WW78, Q9UQ73	Gene names	PSG9, PSG11
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 9 precursor (PSBG-9) (Pregnancy-specific glycoprotein 9) (Pregnancy-specific beta-1 glycoprotein B) (PS-beta-B) (PS34) (Pregnancy-specific glycoprotein 7) (PSG7).

SIG12_HUMAN
NC score	0.140184 (rank : 362)	θ value	θ > 10 (rank : 782)
Query Neighborhood Hits	207	Target Neighborhood Hits	245	Shared Neighborhood Hits	71
SwissProt Accessions	Q96PQ1, Q8IYH7	Gene names	SIGLEC12, SIGLECL1, SLG
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1).

UNC5A_MOUSE
NC score	0.138685 (rank : 363)	θ value	θ > 10 (rank : 860)
Query Neighborhood Hits	207	Target Neighborhood Hits	203	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K1S4, Q6PEF7, Q80T71	Gene names	Unc5a, Kiaa1976, Unc5h1
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5A precursor (Unc-5 homolog A) (Unc-5 homolog 1).

LRRN3_MOUSE
NC score	0.137346 (rank : 364)	θ value	θ > 10 (rank : 568)
Query Neighborhood Hits	207	Target Neighborhood Hits	455	Shared Neighborhood Hits	85
SwissProt Accessions	Q8CBC6, P97860	Gene names	Lrrn3
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats neuronal protein 3 precursor (Neuronal leucine- rich repeat protein 3) (NLRR-3).

PDL1_HUMAN
NC score	0.137328 (rank : 365)	θ value	θ > 10 (rank : 666)
Query Neighborhood Hits	207	Target Neighborhood Hits	195	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NZQ7, Q66RK1, Q6WEX4, Q9NUZ5	Gene names	CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

I27RA_HUMAN
NC score	0.137207 (rank : 366)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	207	Target Neighborhood Hits	60	Shared Neighborhood Hits	38
SwissProt Accessions	Q6UWB1, O60624	Gene names	IL27RA, CRL1, TCCR, WSX1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR) (Protein CRL1).

IGS21_HUMAN
NC score	0.136876 (rank : 367)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	207	Target Neighborhood Hits	123	Shared Neighborhood Hits	43
SwissProt Accessions	Q96ID5, Q8NBR8	Gene names	IGSF21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

IGS21_MOUSE
NC score	0.135164 (rank : 368)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	207	Target Neighborhood Hits	118	Shared Neighborhood Hits	42
SwissProt Accessions	Q7TNR6	Gene names	Igsf21
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 21 precursor.

PSG5_HUMAN
NC score	0.134517 (rank : 369)	θ value	θ > 10 (rank : 693)
Query Neighborhood Hits	207	Target Neighborhood Hits	231	Shared Neighborhood Hits	64
SwissProt Accessions	Q15238, Q15239, Q96QJ1, Q9UQ75	Gene names	PSG5
Domain Architecture
Description	Pregnancy-specific beta-1-glycoprotein 5 precursor (PSBG-5) (Fetal liver non-specific cross-reactive antigen 3) (FL-NCA-3).

PGFRL_HUMAN
NC score	0.134272 (rank : 370)	θ value	θ > 10 (rank : 678)
Query Neighborhood Hits	207	Target Neighborhood Hits	115	Shared Neighborhood Hits	49
SwissProt Accessions	Q15198, Q6FH04	Gene names	PDGFRL, PRLTS
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor (PDGF receptor beta-like tumor suppressor).

LRRN5_HUMAN
NC score	0.129745 (rank : 371)	θ value	θ > 10 (rank : 569)
Query Neighborhood Hits	207	Target Neighborhood Hits	493	Shared Neighborhood Hits	82
SwissProt Accessions	O75325, Q5T0Y0, Q6UXM0, Q8N182	Gene names	LRRN5, GAC1, LRRN2
Domain Architecture
Description	Leucine-rich repeats neuronal protein 5 precursor (Glioma amplified on chromosome 1 protein).

PECA1_HUMAN
NC score	0.128385 (rank : 372)	θ value	θ > 10 (rank : 670)
Query Neighborhood Hits	207	Target Neighborhood Hits	178	Shared Neighborhood Hits	50
SwissProt Accessions	P16284, Q6LDA9, Q8TBH1, Q96RF5, Q96RF6, Q9NP65, Q9NPB7, Q9NPG9, Q9NQS9, Q9NQT0, Q9NQT1, Q9NQT2	Gene names	PECAM1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (EndoCAM) (GPIIA') (CD31 antigen).

SIGL6_HUMAN
NC score	0.127387 (rank : 373)	θ value	θ > 10 (rank : 786)
Query Neighborhood Hits	207	Target Neighborhood Hits	233	Shared Neighborhood Hits	67
SwissProt Accessions	O43699, O15388, O43700	Gene names	SIGLEC6, CD33L, CD33L1, OBBP1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 6 precursor (Siglec-6) (Obesity- binding protein 1) (OB-BP1) (CD33 antigen-like 1) (CDw327 antigen).

IL1R1_HUMAN
NC score	0.127236 (rank : 374)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	207	Target Neighborhood Hits	140	Shared Neighborhood Hits	50
SwissProt Accessions	P14778	Gene names	IL1R1, IL1R, IL1RA, IL1RT1
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (IL-1RT1) (IL-1R- alpha) (p80) (CD121a antigen).

ILRL2_MOUSE
NC score	0.126815 (rank : 375)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	207	Target Neighborhood Hits	158	Shared Neighborhood Hits	59
SwissProt Accessions	Q9ERS7	Gene names	Il1rl2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2).

NTRK1_HUMAN
NC score	0.126256 (rank : 376)	θ value	θ > 10 (rank : 652)
Query Neighborhood Hits	207	Target Neighborhood Hits	1023	Shared Neighborhood Hits	99
SwissProt Accessions	P04629, P08119, Q15655, Q15656, Q5D056, Q5VZS2, Q9UIU7	Gene names	NTRK1, TRK
Domain Architecture
Description	High affinity nerve growth factor receptor precursor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1 transforming tyrosine kinase protein) (p140-TrkA) (Trk-A).

IL1R1_MOUSE
NC score	0.126015 (rank : 377)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	207	Target Neighborhood Hits	142	Shared Neighborhood Hits	56
SwissProt Accessions	P13504	Gene names	Il1r1, Il-1r1, Il1ra
Domain Architecture
Description	Interleukin-1 receptor type I precursor (IL-1R-1) (p80) (CD121a antigen).

PTN9_MOUSE
NC score	0.122597 (rank : 378)	θ value	θ > 10 (rank : 730)
Query Neighborhood Hits	207	Target Neighborhood Hits	78	Shared Neighborhood Hits	15
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_HUMAN
NC score	0.122184 (rank : 379)	θ value	θ > 10 (rank : 729)
Query Neighborhood Hits	207	Target Neighborhood Hits	79	Shared Neighborhood Hits	15
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN7_MOUSE
NC score	0.122029 (rank : 380)	θ value	θ > 10 (rank : 728)
Query Neighborhood Hits	207	Target Neighborhood Hits	71	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN5_MOUSE
NC score	0.121958 (rank : 381)	θ value	θ > 10 (rank : 724)
Query Neighborhood Hits	207	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN5_HUMAN
NC score	0.121946 (rank : 382)	θ value	θ > 10 (rank : 723)
Query Neighborhood Hits	207	Target Neighborhood Hits	80	Shared Neighborhood Hits	15
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN7_HUMAN
NC score	0.121879 (rank : 383)	θ value	θ > 10 (rank : 727)
Query Neighborhood Hits	207	Target Neighborhood Hits	75	Shared Neighborhood Hits	15
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN2_HUMAN
NC score	0.121131 (rank : 384)	θ value	θ > 10 (rank : 719)
Query Neighborhood Hits	207	Target Neighborhood Hits	92	Shared Neighborhood Hits	15
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN2_MOUSE
NC score	0.120227 (rank : 385)	θ value	θ > 10 (rank : 720)
Query Neighborhood Hits	207	Target Neighborhood Hits	107	Shared Neighborhood Hits	15
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTPRN_HUMAN
NC score	0.120149 (rank : 386)	θ value	θ > 10 (rank : 739)
Query Neighborhood Hits	207	Target Neighborhood Hits	156	Shared Neighborhood Hits	17
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

TRIO_HUMAN
NC score	0.120024 (rank : 387)	θ value	θ > 10 (rank : 848)
Query Neighborhood Hits	207	Target Neighborhood Hits	1580	Shared Neighborhood Hits	114
SwissProt Accessions	O75962, Q13458	Gene names	TRIO
Domain Architecture
Description	Triple functional domain protein (PTPRF-interacting protein).

PTPRN_MOUSE
NC score	0.119796 (rank : 388)	θ value	θ > 10 (rank : 740)
Query Neighborhood Hits	207	Target Neighborhood Hits	240	Shared Neighborhood Hits	22
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPR2_MOUSE
NC score	0.119754 (rank : 389)	θ value	θ > 10 (rank : 732)
Query Neighborhood Hits	207	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPR2_HUMAN
NC score	0.119590 (rank : 390)	θ value	θ > 10 (rank : 731)
Query Neighborhood Hits	207	Target Neighborhood Hits	103	Shared Neighborhood Hits	15
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

FLT3_MOUSE
NC score	0.119360 (rank : 391)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	207	Target Neighborhood Hits	847	Shared Neighborhood Hits	80
SwissProt Accessions	Q00342	Gene names	Flt3, Flk-2, Flt-3
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor flk-2) (Fetal liver kinase 2) (Tyrosine-protein kinase FLT3) (CD135 antigen).

PTPRR_MOUSE
NC score	0.119278 (rank : 392)	θ value	θ > 10 (rank : 743)
Query Neighborhood Hits	207	Target Neighborhood Hits	84	Shared Neighborhood Hits	16
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTN1_HUMAN
NC score	0.119205 (rank : 393)	θ value	θ > 10 (rank : 711)
Query Neighborhood Hits	207	Target Neighborhood Hits	84	Shared Neighborhood Hits	15
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTPRR_HUMAN
NC score	0.119136 (rank : 394)	θ value	θ > 10 (rank : 742)
Query Neighborhood Hits	207	Target Neighborhood Hits	77	Shared Neighborhood Hits	15
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTN1_MOUSE
NC score	0.118992 (rank : 395)	θ value	θ > 10 (rank : 712)
Query Neighborhood Hits	207	Target Neighborhood Hits	85	Shared Neighborhood Hits	15
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN22_HUMAN
NC score	0.118640 (rank : 396)	θ value	θ > 10 (rank : 715)
Query Neighborhood Hits	207	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PVRL3_MOUSE
NC score	0.118529 (rank : 397)	θ value	θ > 10 (rank : 751)
Query Neighborhood Hits	207	Target Neighborhood Hits	212	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JLB9, Q9D006, Q9JLB7, Q9JLB8	Gene names	Pvrl3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Cell adhesion molecule nectin-3) (Nectin-3) (CDw113 antigen).

PTN18_MOUSE
NC score	0.117742 (rank : 398)	θ value	θ > 10 (rank : 710)
Query Neighborhood Hits	207	Target Neighborhood Hits	134	Shared Neighborhood Hits	15
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN12_HUMAN
NC score	0.116408 (rank : 399)	θ value	θ > 10 (rank : 703)
Query Neighborhood Hits	207	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN18_HUMAN
NC score	0.116289 (rank : 400)	θ value	θ > 10 (rank : 709)
Query Neighborhood Hits	207	Target Neighborhood Hits	73	Shared Neighborhood Hits	15
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN22_MOUSE
NC score	0.115934 (rank : 401)	θ value	θ > 10 (rank : 716)
Query Neighborhood Hits	207	Target Neighborhood Hits	179	Shared Neighborhood Hits	16
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN12_MOUSE
NC score	0.115897 (rank : 402)	θ value	θ > 10 (rank : 704)
Query Neighborhood Hits	207	Target Neighborhood Hits	123	Shared Neighborhood Hits	15
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

CT075_MOUSE
NC score	0.115189 (rank : 403)	θ value	5.27518 (rank : 187)
Query Neighborhood Hits	207	Target Neighborhood Hits	358	Shared Neighborhood Hits	58
SwissProt Accessions	P59383	Gene names
Domain Architecture
Description	Uncharacterized protein C20orf75 homolog precursor.

PDL2_MOUSE
NC score	0.114767 (rank : 404)	θ value	θ > 10 (rank : 669)
Query Neighborhood Hits	207	Target Neighborhood Hits	116	Shared Neighborhood Hits	46
SwissProt Accessions	Q9WUL5	Gene names	Pdcd1lg2, B7dc, Btdc, Cd273, Pdl2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

LRC24_HUMAN
NC score	0.113000 (rank : 405)	θ value	θ > 10 (rank : 539)
Query Neighborhood Hits	207	Target Neighborhood Hits	404	Shared Neighborhood Hits	74
SwissProt Accessions	Q50LG9	Gene names	LRRC24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

PTN6_MOUSE
NC score	0.111567 (rank : 406)	θ value	θ > 10 (rank : 726)
Query Neighborhood Hits	207	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN6_HUMAN
NC score	0.111489 (rank : 407)	θ value	θ > 10 (rank : 725)
Query Neighborhood Hits	207	Target Neighborhood Hits	234	Shared Neighborhood Hits	15
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

LTK_HUMAN
NC score	0.109623 (rank : 408)	θ value	θ > 10 (rank : 572)
Query Neighborhood Hits	207	Target Neighborhood Hits	774	Shared Neighborhood Hits	52
SwissProt Accessions	P29376	Gene names	LTK, TYK1
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1) (Protein tyrosine kinase 1).

RYK_HUMAN
NC score	0.109011 (rank : 409)	θ value	θ > 10 (rank : 777)
Query Neighborhood Hits	207	Target Neighborhood Hits	701	Shared Neighborhood Hits	47
SwissProt Accessions	P34925, Q04696	Gene names	RYK, JTK5A
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1).

PTN11_HUMAN
NC score	0.108964 (rank : 410)	θ value	θ > 10 (rank : 701)
Query Neighborhood Hits	207	Target Neighborhood Hits	227	Shared Neighborhood Hits	15
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
NC score	0.108956 (rank : 411)	θ value	θ > 10 (rank : 702)
Query Neighborhood Hits	207	Target Neighborhood Hits	227	Shared Neighborhood Hits	15
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

LTK_MOUSE
NC score	0.108904 (rank : 412)	θ value	θ > 10 (rank : 573)
Query Neighborhood Hits	207	Target Neighborhood Hits	770	Shared Neighborhood Hits	51
SwissProt Accessions	P08923	Gene names	Ltk
Domain Architecture
Description	Leukocyte tyrosine kinase receptor precursor (EC 2.7.10.1).

ALK_MOUSE
NC score	0.107984 (rank : 413)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	207	Target Neighborhood Hits	811	Shared Neighborhood Hits	56
SwissProt Accessions	P97793	Gene names	Alk
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

PVRL3_HUMAN
NC score	0.107722 (rank : 414)	θ value	θ > 10 (rank : 750)
Query Neighborhood Hits	207	Target Neighborhood Hits	204	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NQS3, Q6NVZ3, Q8WVU4, Q9BVA9, Q9Y412	Gene names	PVRL3, PRR3
Domain Architecture	No domain graphic available
Description	Poliovirus receptor-related protein 3 precursor (Nectin-3) (CDw113 antigen).

RYK_MOUSE
NC score	0.107436 (rank : 415)	θ value	θ > 10 (rank : 778)
Query Neighborhood Hits	207	Target Neighborhood Hits	715	Shared Neighborhood Hits	47
SwissProt Accessions	Q01887, Q61890	Gene names	Ryk, Mrk
Domain Architecture
Description	Tyrosine-protein kinase RYK precursor (EC 2.7.10.1) (Kinase VIK) (NYK- R) (Met-related kinase).

ILRL1_HUMAN
NC score	0.107433 (rank : 416)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	207	Target Neighborhood Hits	167	Shared Neighborhood Hits	48
SwissProt Accessions	Q01638, Q53TU7, Q8NEJ3, Q9ULV7, Q9UQ44	Gene names	IL1RL1, DER4, ST2, T1
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein).

ALK_HUMAN
NC score	0.107152 (rank : 417)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	207	Target Neighborhood Hits	795	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UM73, Q9Y4K6	Gene names	ALK
Domain Architecture
Description	ALK tyrosine kinase receptor precursor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD246 antigen).

I11RB_MOUSE
NC score	0.106731 (rank : 418)	θ value	8.99809 (rank : 201)
Query Neighborhood Hits	207	Target Neighborhood Hits	101	Shared Neighborhood Hits	40
SwissProt Accessions	P70225, O09074, Q78DW8	Gene names	Il11ra2
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-2 chain precursor (IL-11R-alpha-2) (Interleukin-11 receptor beta chain) (IL-11R-beta).

FLT3_HUMAN
NC score	0.106325 (rank : 419)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	207	Target Neighborhood Hits	843	Shared Neighborhood Hits	67
SwissProt Accessions	P36888, Q13414	Gene names	FLT3, STK1
Domain Architecture
Description	FL cytokine receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor FLT3) (Stem cell tyrosine kinase 1) (STK-1) (CD135 antigen).

PVRL1_HUMAN
NC score	0.106056 (rank : 420)	θ value	θ > 10 (rank : 746)
Query Neighborhood Hits	207	Target Neighborhood Hits	219	Shared Neighborhood Hits	43
SwissProt Accessions	Q15223, O75465, Q9HBE6, Q9HBW2	Gene names	PVRL1, HVEC, PRR1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (Herpesvirus Ig-like receptor) (HIgR) (CD111 antigen).

HHLA2_HUMAN
NC score	0.106038 (rank : 421)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	207	Target Neighborhood Hits	140	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UM44, Q9NWQ6	Gene names	HHLA2
Domain Architecture	No domain graphic available
Description	HERV-H LTR-associating protein 2 precursor (Human endogenous retrovirus-H long terminal repeat-associating protein 2).

PDL1_MOUSE
NC score	0.104874 (rank : 422)	θ value	θ > 10 (rank : 667)
Query Neighborhood Hits	207	Target Neighborhood Hits	168	Shared Neighborhood Hits	48
SwissProt Accessions	Q9EP73	Gene names	Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 1 precursor (Programmed death ligand 1) (PD-L1) (PDCD1 ligand 1) (B7 homolog 1) (B7-H1) (CD274 antigen).

CD79A_HUMAN
NC score	0.104691 (rank : 423)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	207	Target Neighborhood Hits	102	Shared Neighborhood Hits	36
SwissProt Accessions	P11912	Gene names	CD79A, IGA, MB1
Domain Architecture
Description	B-cell antigen receptor complex-associated protein alpha-chain precursor (Ig-alpha) (MB-1 membrane glycoprotein) (Surface IgM- associated protein) (Membrane-bound immunoglobulin-associated protein) (CD79a antigen).

LEPR_HUMAN
NC score	0.104285 (rank : 424)	θ value	θ > 10 (rank : 531)
Query Neighborhood Hits	207	Target Neighborhood Hits	112	Shared Neighborhood Hits	59
SwissProt Accessions	P48357, Q13592, Q13593, Q13594, Q92919, Q92920, Q92921	Gene names	LEPR, DB, OBR
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (HuB219) (CD295 antigen).

CEAM7_HUMAN
NC score	0.103690 (rank : 425)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	207	Target Neighborhood Hits	170	Shared Neighborhood Hits	54
SwissProt Accessions	Q14002, O15148, O15149, Q13983, Q9UPJ2	Gene names	CEACAM7, CGM2
Domain Architecture
Description	Carcinoembryonic antigen-related cell adhesion molecule 7 precursor (Carcinoembryonic antigen CGM2).

PECA1_MOUSE
NC score	0.103270 (rank : 426)	θ value	θ > 10 (rank : 671)
Query Neighborhood Hits	207	Target Neighborhood Hits	126	Shared Neighborhood Hits	38
SwissProt Accessions	Q08481	Gene names	Pecam1, Pecam, Pecam-1
Domain Architecture
Description	Platelet endothelial cell adhesion molecule precursor (PECAM-1) (CD31 antigen).

LRC4B_MOUSE
NC score	0.102511 (rank : 427)	θ value	θ > 10 (rank : 542)
Query Neighborhood Hits	207	Target Neighborhood Hits	484	Shared Neighborhood Hits	73
SwissProt Accessions	P0C192	Gene names	Lrrc4b, Lrig4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

DDR1_HUMAN
NC score	0.102434 (rank : 428)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	207	Target Neighborhood Hits	819	Shared Neighborhood Hits	50
SwissProt Accessions	Q08345, Q14196, Q16562, Q5ST12, Q9UD37	Gene names	DDR1, CAK, EDDR1, RTK6, TRKE
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (TRK E) (Protein-tyrosine kinase RTK 6) (HGK2) (CD167a antigen).

JAML1_MOUSE
NC score	0.101983 (rank : 429)	θ value	θ > 10 (rank : 472)
Query Neighborhood Hits	207	Target Neighborhood Hits	185	Shared Neighborhood Hits	38
SwissProt Accessions	Q80UL9, Q5DTC4	Gene names	Amica1, Gm638, Jaml
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (mCrea7).

DDR1_MOUSE
NC score	0.101629 (rank : 430)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	207	Target Neighborhood Hits	818	Shared Neighborhood Hits	50
SwissProt Accessions	Q03146	Gene names	Ddr1, Cak, Eddr1, Mpk6
Domain Architecture
Description	Epithelial discoidin domain-containing receptor 1 precursor (EC 2.7.10.1) (Epithelial discoidin domain receptor 1) (Tyrosine kinase DDR) (Discoidin receptor tyrosine kinase) (Tyrosine-protein kinase CAK) (Cell adhesion kinase) (Protein-tyrosine kinase MPK-6) (CD167a antigen).

TNK1_HUMAN
NC score	0.101572 (rank : 431)	θ value	θ > 10 (rank : 841)
Query Neighborhood Hits	207	Target Neighborhood Hits	815	Shared Neighborhood Hits	50
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

DDR2_HUMAN
NC score	0.101254 (rank : 432)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	207	Target Neighborhood Hits	818	Shared Neighborhood Hits	50
SwissProt Accessions	Q16832	Gene names	DDR2, NTRKR3, TKT, TYRO10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

STYK1_MOUSE
NC score	0.101085 (rank : 433)	θ value	θ > 10 (rank : 824)
Query Neighborhood Hits	207	Target Neighborhood Hits	779	Shared Neighborhood Hits	51
SwissProt Accessions	Q6J9G1, Q8BZH6, Q8BZT1	Gene names	Styk1, Nok
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (mNOK).

CD276_MOUSE
NC score	0.100945 (rank : 434)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	207	Target Neighborhood Hits	243	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VE98	Gene names	Cd276, B7h3
Domain Architecture	No domain graphic available
Description	CD276 antigen precursor (Costimulatory molecule) (B7 homolog 3) (B7- H3).

PGFRL_MOUSE
NC score	0.100532 (rank : 435)	θ value	θ > 10 (rank : 679)
Query Neighborhood Hits	207	Target Neighborhood Hits	106	Shared Neighborhood Hits	43
SwissProt Accessions	Q6PE55, Q3V182, Q9D0Z1	Gene names	Pdgfrl
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor receptor-like protein precursor.

LRC4B_HUMAN
NC score	0.100479 (rank : 436)	θ value	θ > 10 (rank : 541)
Query Neighborhood Hits	207	Target Neighborhood Hits	479	Shared Neighborhood Hits	72
SwissProt Accessions	Q9NT99, Q3ZCQ4, Q58F20	Gene names	LRRC4B, LRIG4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4B precursor.

FAK2_HUMAN
NC score	0.100327 (rank : 437)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	207	Target Neighborhood Hits	847	Shared Neighborhood Hits	50
SwissProt Accessions	Q14289, Q13475, Q14290, Q16709	Gene names	PTK2B, FAK2, PYK2, RAFTK
Domain Architecture
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

DDR2_MOUSE
NC score	0.100270 (rank : 438)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	207	Target Neighborhood Hits	813	Shared Neighborhood Hits	50
SwissProt Accessions	Q62371	Gene names	Ddr2, Ntrkr3, Tkt, Tyro10
Domain Architecture
Description	Discoidin domain-containing receptor 2 precursor (EC 2.7.10.1) (Discoidin domain receptor 2) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO 10) (Neurotrophic tyrosine kinase, receptor-related 3) (CD167b antigen).

FAK1_HUMAN
NC score	0.100209 (rank : 439)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	207	Target Neighborhood Hits	850	Shared Neighborhood Hits	50
SwissProt Accessions	Q05397, Q14291, Q9UD85	Gene names	PTK2, FAK, FAK1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK) (Protein- tyrosine kinase 2).

FAK1_MOUSE
NC score	0.099895 (rank : 440)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	207	Target Neighborhood Hits	850	Shared Neighborhood Hits	50
SwissProt Accessions	P34152, O08578	Gene names	Ptk2, Fadk, Fak, Fak1
Domain Architecture
Description	Focal adhesion kinase 1 (EC 2.7.10.2) (FADK 1) (pp125FAK).

PVRL1_MOUSE
NC score	0.099866 (rank : 441)	θ value	θ > 10 (rank : 747)
Query Neighborhood Hits	207	Target Neighborhood Hits	201	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JKF6, Q9ERL5, Q9JI17	Gene names	Pvrl1, Hvec, Prr1
Domain Architecture
Description	Poliovirus receptor-related protein 1 precursor (Herpes virus entry mediator C) (HveC) (Nectin-1) (CD111 antigen).

FAK2_MOUSE
NC score	0.099756 (rank : 442)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	207	Target Neighborhood Hits	851	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QVP9	Gene names	Ptk2b, Fak2, Pyk2, Raftk
Domain Architecture	No domain graphic available
Description	Protein tyrosine kinase 2 beta (EC 2.7.10.2) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2) (Cell adhesion kinase beta) (CAK beta) (Calcium-dependent tyrosine kinase) (CADTK) (Related adhesion focal tyrosine kinase) (RAFTK).

TNK1_MOUSE
NC score	0.099724 (rank : 443)	θ value	θ > 10 (rank : 842)
Query Neighborhood Hits	207	Target Neighborhood Hits	806	Shared Neighborhood Hits	53
SwissProt Accessions	Q99ML2, Q8CCC4, Q8K0X9, Q91V11	Gene names	Tnk1, Kos1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (Kinase of embryonic stem cells).

ZAP70_HUMAN
NC score	0.098979 (rank : 444)	θ value	θ > 10 (rank : 887)
Query Neighborhood Hits	207	Target Neighborhood Hits	893	Shared Neighborhood Hits	50
SwissProt Accessions	P43403	Gene names	ZAP70, SRK
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

ERBB4_HUMAN
NC score	0.098919 (rank : 445)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	207	Target Neighborhood Hits	910	Shared Neighborhood Hits	54
SwissProt Accessions	Q15303	Gene names	ERBB4, HER4
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-4 precursor (EC 2.7.10.1) (p180erbB4) (Tyrosine kinase-type cell surface receptor HER4).

ZAP70_MOUSE
NC score	0.098895 (rank : 446)	θ value	θ > 10 (rank : 888)
Query Neighborhood Hits	207	Target Neighborhood Hits	905	Shared Neighborhood Hits	50
SwissProt Accessions	P43404	Gene names	Zap70, Srk, Zap-70
Domain Architecture
Description	Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-associated protein) (Syk-related tyrosine kinase).

NGL1_MOUSE
NC score	0.098512 (rank : 447)	θ value	θ > 10 (rank : 643)
Query Neighborhood Hits	207	Target Neighborhood Hits	512	Shared Neighborhood Hits	70
SwissProt Accessions	Q8C031, Q8BGH8	Gene names	Lrrc4c, Ngl1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

STYK1_HUMAN
NC score	0.098511 (rank : 448)	θ value	θ > 10 (rank : 823)
Query Neighborhood Hits	207	Target Neighborhood Hits	786	Shared Neighborhood Hits	50
SwissProt Accessions	Q6J9G0, Q9BXY2, Q9NSH1	Gene names	STYK1, NOK
Domain Architecture	No domain graphic available
Description	Tyrosine protein-kinase STYK1 (EC 2.7.10.2) (Serine/threonine/tyrosine kinase 1) (Novel oncogene with kinase-domain) (Protein PK-unique).

NGL1_HUMAN
NC score	0.098297 (rank : 449)	θ value	θ > 10 (rank : 642)
Query Neighborhood Hits	207	Target Neighborhood Hits	511	Shared Neighborhood Hits	70
SwissProt Accessions	Q9HCJ2, Q7L0N3	Gene names	LRRC4C, KIAA1580, NGL1
Domain Architecture	No domain graphic available
Description	Netrin-G1 ligand precursor (NGL-1) (Leucine-rich repeat-containing protein 4C).

PTN23_MOUSE
NC score	0.098189 (rank : 450)	θ value	θ > 10 (rank : 718)
Query Neighborhood Hits	207	Target Neighborhood Hits	726	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

FCERA_HUMAN
NC score	0.098090 (rank : 451)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	207	Target Neighborhood Hits	150	Shared Neighborhood Hits	39
SwissProt Accessions	P12319	Gene names	FCER1A, FCE1A
Domain Architecture
Description	High affinity immunoglobulin epsilon receptor alpha-subunit precursor (FcERI) (IgE Fc receptor, alpha-subunit) (Fc-epsilon RI-alpha).

ACK1_MOUSE
NC score	0.098073 (rank : 452)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	207	Target Neighborhood Hits	1080	Shared Neighborhood Hits	53
SwissProt Accessions	O54967, Q8C2U0, Q8K0K4	Gene names	Tnk2, Ack1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Non-receptor protein tyrosine kinase Ack) (Tyrosine kinase non-receptor protein 2).

ERBB2_HUMAN
NC score	0.097852 (rank : 453)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	207	Target Neighborhood Hits	1073	Shared Neighborhood Hits	56
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

EGFR_MOUSE
NC score	0.097463 (rank : 454)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	207	Target Neighborhood Hits	927	Shared Neighborhood Hits	54
SwissProt Accessions	Q01279	Gene names	Egfr
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1).

LEPR_MOUSE
NC score	0.097274 (rank : 455)	θ value	θ > 10 (rank : 532)
Query Neighborhood Hits	207	Target Neighborhood Hits	109	Shared Neighborhood Hits	50
SwissProt Accessions	P48356, O35686, O54986, Q61215, Q64309, Q9QWG3, Q9QWV5	Gene names	Lepr, db, Obr
Domain Architecture
Description	Leptin receptor precursor (LEP-R) (OB receptor) (OB-R) (B219) (CD295 antigen).

ACK1_HUMAN
NC score	0.097123 (rank : 456)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	207	Target Neighborhood Hits	1140	Shared Neighborhood Hits	53
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

KSYK_HUMAN
NC score	0.097107 (rank : 457)	θ value	θ > 10 (rank : 507)
Query Neighborhood Hits	207	Target Neighborhood Hits	901	Shared Neighborhood Hits	50
SwissProt Accessions	P43405	Gene names	SYK
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

ERBB2_MOUSE
NC score	0.097024 (rank : 458)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	207	Target Neighborhood Hits	918	Shared Neighborhood Hits	51
SwissProt Accessions	P70424, Q61525, Q6ZPE0	Gene names	Erbb2, Kiaa3023, Neu
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene).

KSYK_MOUSE
NC score	0.096905 (rank : 459)	θ value	θ > 10 (rank : 508)
Query Neighborhood Hits	207	Target Neighborhood Hits	944	Shared Neighborhood Hits	50
SwissProt Accessions	P48025	Gene names	Syk
Domain Architecture
Description	Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase).

EGFR_HUMAN
NC score	0.096673 (rank : 460)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	207	Target Neighborhood Hits	939	Shared Neighborhood Hits	52
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

ERBB3_HUMAN
NC score	0.096486 (rank : 461)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	207	Target Neighborhood Hits	918	Shared Neighborhood Hits	52
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

MET_MOUSE
NC score	0.096451 (rank : 462)	θ value	θ > 10 (rank : 602)
Query Neighborhood Hits	207	Target Neighborhood Hits	844	Shared Neighborhood Hits	50
SwissProt Accessions	P16056, Q62125	Gene names	Met
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

MET_HUMAN
NC score	0.096289 (rank : 463)	θ value	θ > 10 (rank : 601)
Query Neighborhood Hits	207	Target Neighborhood Hits	831	Shared Neighborhood Hits	49
SwissProt Accessions	P08581, O60366, Q12875, Q9UDX7, Q9UPL8	Gene names	MET
Domain Architecture
Description	Hepatocyte growth factor receptor precursor (EC 2.7.10.1) (HGF receptor) (Scatter factor receptor) (SF receptor) (HGF/SF receptor) (Met proto-oncogene tyrosine kinase) (c-Met).

LRC24_MOUSE
NC score	0.095890 (rank : 464)	θ value	θ > 10 (rank : 540)
Query Neighborhood Hits	207	Target Neighborhood Hits	387	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BHA1	Gene names	Lrrc24
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 24 precursor.

PTN23_HUMAN
NC score	0.095739 (rank : 465)	θ value	θ > 10 (rank : 717)
Query Neighborhood Hits	207	Target Neighborhood Hits	646	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

RET_MOUSE
NC score	0.095412 (rank : 466)	θ value	θ > 10 (rank : 758)
Query Neighborhood Hits	207	Target Neighborhood Hits	884	Shared Neighborhood Hits	52
SwissProt Accessions	P35546, Q8BQ34, Q9QXH9	Gene names	Ret
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

RET_HUMAN
NC score	0.095234 (rank : 467)	θ value	θ > 10 (rank : 757)
Query Neighborhood Hits	207	Target Neighborhood Hits	873	Shared Neighborhood Hits	49
SwissProt Accessions	P07949, Q15250	Gene names	RET
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase receptor ret precursor (EC 2.7.10.1) (C-ret).

PTN14_HUMAN
NC score	0.094987 (rank : 468)	θ value	θ > 10 (rank : 707)
Query Neighborhood Hits	207	Target Neighborhood Hits	163	Shared Neighborhood Hits	16
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

RON_MOUSE
NC score	0.094711 (rank : 469)	θ value	θ > 10 (rank : 772)
Query Neighborhood Hits	207	Target Neighborhood Hits	836	Shared Neighborhood Hits	49
SwissProt Accessions	Q62190, Q62555	Gene names	Mst1r, Ron, Stk
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (Stem cell-derived tyrosine kinase) (CDw136 antigen) [Contains: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

PTN21_MOUSE
NC score	0.094676 (rank : 470)	θ value	θ > 10 (rank : 714)
Query Neighborhood Hits	207	Target Neighborhood Hits	155	Shared Neighborhood Hits	17
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN14_MOUSE
NC score	0.094614 (rank : 471)	θ value	θ > 10 (rank : 708)
Query Neighborhood Hits	207	Target Neighborhood Hits	142	Shared Neighborhood Hits	16
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

ERBB3_MOUSE
NC score	0.094503 (rank : 472)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	207	Target Neighborhood Hits	898	Shared Neighborhood Hits	51
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

I11RA_MOUSE
NC score	0.094319 (rank : 473)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	207	Target Neighborhood Hits	95	Shared Neighborhood Hits	35
SwissProt Accessions	Q64385, Q6NSQ0	Gene names	Il11ra1, Etl2, Il11ra
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha-1 chain precursor (IL-11R-alpha-1) (IL- 11RA1) (IL-11R-alpha) (IL-11RA) (Enhancer trap locus homolog 2) (Etl- 2) (NR-1).

FES_HUMAN
NC score	0.094199 (rank : 474)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	207	Target Neighborhood Hits	978	Shared Neighborhood Hits	50
SwissProt Accessions	P07332	Gene names	FES, FPS
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

FES_MOUSE
NC score	0.094070 (rank : 475)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	207	Target Neighborhood Hits	980	Shared Neighborhood Hits	50
SwissProt Accessions	P16879, Q62122	Gene names	Fes, Fps
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fes/Fps (EC 2.7.10.2) (C-Fes).

PTN21_HUMAN
NC score	0.093838 (rank : 476)	θ value	θ > 10 (rank : 713)
Query Neighborhood Hits	207	Target Neighborhood Hits	143	Shared Neighborhood Hits	15
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

SRMS_HUMAN
NC score	0.093689 (rank : 477)	θ value	θ > 10 (rank : 800)
Query Neighborhood Hits	207	Target Neighborhood Hits	946	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

PTN3_HUMAN
NC score	0.093012 (rank : 478)	θ value	θ > 10 (rank : 721)
Query Neighborhood Hits	207	Target Neighborhood Hits	258	Shared Neighborhood Hits	18
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

FCGR1_HUMAN
NC score	0.092876 (rank : 479)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	207	Target Neighborhood Hits	145	Shared Neighborhood Hits	42
SwissProt Accessions	P12314, P12315, Q92495, Q92663	Gene names	FCGR1A, FCG1, FCGR1, IGFR1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I) (CD64 antigen).

RON_HUMAN
NC score	0.092869 (rank : 480)	θ value	θ > 10 (rank : 771)
Query Neighborhood Hits	207	Target Neighborhood Hits	842	Shared Neighborhood Hits	49
SwissProt Accessions	Q04912	Gene names	MST1R, RON
Domain Architecture
Description	Macrophage-stimulating protein receptor precursor (EC 2.7.10.1) (MSP receptor) (p185-Ron) (CDw136 antigen) [Contains: Macrophage- stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain].

FER_HUMAN
NC score	0.092774 (rank : 481)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	207	Target Neighborhood Hits	1278	Shared Neighborhood Hits	50
SwissProt Accessions	P16591	Gene names	FER, TYK3
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2) (p94-FER) (c- FER).

AATK_MOUSE
NC score	0.092438 (rank : 482)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	207	Target Neighborhood Hits	942	Shared Neighborhood Hits	51
SwissProt Accessions	Q80YE4, O35211, Q3U2U5, Q3UHR8, Q66JN3, Q80YE3, Q8CB63, Q8CHE2	Gene names	Aatk, Kiaa0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase).

PVR_HUMAN
NC score	0.092289 (rank : 483)	θ value	θ > 10 (rank : 752)
Query Neighborhood Hits	207	Target Neighborhood Hits	195	Shared Neighborhood Hits	41
SwissProt Accessions	P15151, P15152, Q15267, Q15268, Q96BJ1	Gene names	PVR, PVS
Domain Architecture
Description	Poliovirus receptor precursor (Nectin-like protein 5) (Necl-5) (CD155 antigen).

SRMS_MOUSE
NC score	0.092230 (rank : 484)	θ value	θ > 10 (rank : 801)
Query Neighborhood Hits	207	Target Neighborhood Hits	964	Shared Neighborhood Hits	51
SwissProt Accessions	Q62270, Q62360, Q923M5	Gene names	Srms, Srm
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2) (PTK70).

TXK_MOUSE
NC score	0.092165 (rank : 485)	θ value	θ > 10 (rank : 850)
Query Neighborhood Hits	207	Target Neighborhood Hits	980	Shared Neighborhood Hits	50
SwissProt Accessions	P42682	Gene names	Txk, Rlk
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2) (PTK-RL-18) (Resting lymphocyte kinase).

NAGPA_MOUSE
NC score	0.091766 (rank : 486)	θ value	θ > 10 (rank : 630)
Query Neighborhood Hits	207	Target Neighborhood Hits	308	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

TXK_HUMAN
NC score	0.091610 (rank : 487)	θ value	θ > 10 (rank : 849)
Query Neighborhood Hits	207	Target Neighborhood Hits	971	Shared Neighborhood Hits	50
SwissProt Accessions	P42681, Q14220	Gene names	TXK
Domain Architecture
Description	Tyrosine-protein kinase TXK (EC 2.7.10.2).

MATK_HUMAN
NC score	0.091492 (rank : 488)	θ value	θ > 10 (rank : 591)
Query Neighborhood Hits	207	Target Neighborhood Hits	954	Shared Neighborhood Hits	50
SwissProt Accessions	P42679	Gene names	MATK, CTK, HYL
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase HYL) (Hematopoietic consensus tyrosine-lacking kinase).

HCK_MOUSE
NC score	0.091326 (rank : 489)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	207	Target Neighborhood Hits	1029	Shared Neighborhood Hits	51
SwissProt Accessions	P08103	Gene names	Hck
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p56-HCK/p59-HCK) (Hemopoietic cell kinase) (B-cell/myeloid kinase) (BMK).

HCK_HUMAN
NC score	0.091009 (rank : 490)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	207	Target Neighborhood Hits	1035	Shared Neighborhood Hits	52
SwissProt Accessions	P08631, Q5T7K1, Q5T7K2, Q96CC0, Q9H5Y5, Q9NUA4, Q9UMJ5	Gene names	HCK
Domain Architecture
Description	Tyrosine-protein kinase HCK (EC 2.7.10.2) (p59-HCK/p60-HCK) (Hemopoietic cell kinase).

MATK_MOUSE
NC score	0.090930 (rank : 491)	θ value	θ > 10 (rank : 592)
Query Neighborhood Hits	207	Target Neighborhood Hits	952	Shared Neighborhood Hits	50
SwissProt Accessions	P41242, Q6LE90	Gene names	Matk, Ctk, Ntk
Domain Architecture
Description	Megakaryocyte-associated tyrosine-protein kinase (EC 2.7.10.2) (Tyrosine-protein kinase CTK) (Protein kinase NTK).

LCK_MOUSE
NC score	0.090810 (rank : 492)	θ value	θ > 10 (rank : 530)
Query Neighborhood Hits	207	Target Neighborhood Hits	981	Shared Neighborhood Hits	51
SwissProt Accessions	P06240, Q61794, Q61795, Q62320, Q91X65	Gene names	Lck, Lsk-t
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK).

BMX_MOUSE
NC score	0.090796 (rank : 493)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	207	Target Neighborhood Hits	912	Shared Neighborhood Hits	50
SwissProt Accessions	P97504	Gene names	Bmx
Domain Architecture	No domain graphic available
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein homolog).

ITK_MOUSE
NC score	0.090752 (rank : 494)	θ value	θ > 10 (rank : 454)
Query Neighborhood Hits	207	Target Neighborhood Hits	985	Shared Neighborhood Hits	50
SwissProt Accessions	Q03526	Gene names	Itk, Emt, Tlk, Tsk
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK).

LCK_HUMAN
NC score	0.090746 (rank : 495)	θ value	θ > 10 (rank : 529)
Query Neighborhood Hits	207	Target Neighborhood Hits	987	Shared Neighborhood Hits	53
SwissProt Accessions	P06239, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q96DW4, Q9NYT8	Gene names	LCK
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (p56-LCK) (Lymphocyte cell-specific protein-tyrosine kinase) (LSK) (T cell- specific protein-tyrosine kinase).

BTK_HUMAN
NC score	0.090724 (rank : 496)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	207	Target Neighborhood Hits	1026	Shared Neighborhood Hits	52
SwissProt Accessions	Q06187	Gene names	BTK, AGMX1, ATK, BPK
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK).

BTK_MOUSE
NC score	0.090670 (rank : 497)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	207	Target Neighborhood Hits	1017	Shared Neighborhood Hits	52
SwissProt Accessions	P35991, Q61365	Gene names	Btk, Bpk
Domain Architecture
Description	Tyrosine-protein kinase BTK (EC 2.7.10.2) (Bruton tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB).

ITK_HUMAN
NC score	0.090508 (rank : 498)	θ value	θ > 10 (rank : 453)
Query Neighborhood Hits	207	Target Neighborhood Hits	1016	Shared Neighborhood Hits	51
SwissProt Accessions	Q08881	Gene names	ITK, EMT, LYK
Domain Architecture
Description	Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk) (Kinase EMT).

BLK_MOUSE
NC score	0.090488 (rank : 499)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	207	Target Neighborhood Hits	992	Shared Neighborhood Hits	51
SwissProt Accessions	P16277	Gene names	Blk
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

PTN4_HUMAN
NC score	0.090167 (rank : 500)	θ value	θ > 10 (rank : 722)
Query Neighborhood Hits	207	Target Neighborhood Hits	303	Shared Neighborhood Hits	16
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

TEC_HUMAN
NC score	0.090117 (rank : 501)	θ value	θ > 10 (rank : 825)
Query Neighborhood Hits	207	Target Neighborhood Hits	1006	Shared Neighborhood Hits	51
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

BMX_HUMAN
NC score	0.090116 (rank : 502)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	207	Target Neighborhood Hits	942	Shared Neighborhood Hits	50
SwissProt Accessions	P51813, O60564, Q12871	Gene names	BMX
Domain Architecture
Description	Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38).

TEC_MOUSE
NC score	0.089988 (rank : 503)	θ value	θ > 10 (rank : 826)
Query Neighborhood Hits	207	Target Neighborhood Hits	1006	Shared Neighborhood Hits	51
SwissProt Accessions	P24604, Q9R1M9, Q9WVN0, Q9WVN1, Q9WVN2, Q9WVN3	Gene names	Tec
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

ABL1_MOUSE
NC score	0.089951 (rank : 504)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	207	Target Neighborhood Hits	1178	Shared Neighborhood Hits	54
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

FGR_HUMAN
NC score	0.089823 (rank : 505)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	207	Target Neighborhood Hits	1067	Shared Neighborhood Hits	52
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

LYN_MOUSE
NC score	0.089754 (rank : 506)	θ value	θ > 10 (rank : 576)
Query Neighborhood Hits	207	Target Neighborhood Hits	1023	Shared Neighborhood Hits	51
SwissProt Accessions	P25911, Q62127	Gene names	Lyn
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

YES_HUMAN
NC score	0.089733 (rank : 507)	θ value	θ > 10 (rank : 884)
Query Neighborhood Hits	207	Target Neighborhood Hits	1059	Shared Neighborhood Hits	53
SwissProt Accessions	P07947	Gene names	YES1, YES
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

AATK_HUMAN
NC score	0.089708 (rank : 508)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	207	Target Neighborhood Hits	1243	Shared Neighborhood Hits	59
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

FRK_HUMAN
NC score	0.089638 (rank : 509)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	207	Target Neighborhood Hits	1058	Shared Neighborhood Hits	51
SwissProt Accessions	P42685, Q13128	Gene names	FRK
Domain Architecture
Description	Tyrosine-protein kinase FRK (EC 2.7.10.2) (Nuclear tyrosine protein kinase RAK).

YES_MOUSE
NC score	0.089558 (rank : 510)	θ value	θ > 10 (rank : 885)
Query Neighborhood Hits	207	Target Neighborhood Hits	1052	Shared Neighborhood Hits	52
SwissProt Accessions	Q04736	Gene names	Yes1, Yes
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Yes (EC 2.7.10.2) (p61-Yes) (c- Yes).

LYN_HUMAN
NC score	0.089521 (rank : 511)	θ value	θ > 10 (rank : 575)
Query Neighborhood Hits	207	Target Neighborhood Hits	1022	Shared Neighborhood Hits	51
SwissProt Accessions	P07948	Gene names	LYN
Domain Architecture
Description	Tyrosine-protein kinase Lyn (EC 2.7.10.2).

BLK_HUMAN
NC score	0.089501 (rank : 512)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	207	Target Neighborhood Hits	994	Shared Neighborhood Hits	51
SwissProt Accessions	P51451, Q16291	Gene names	BLK
Domain Architecture
Description	Tyrosine-protein kinase BLK (EC 2.7.10.2) (B lymphocyte kinase) (p55- BLK).

I11RA_HUMAN
NC score	0.089461 (rank : 513)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	207	Target Neighborhood Hits	138	Shared Neighborhood Hits	42
SwissProt Accessions	Q14626, Q16542, Q7KYJ7	Gene names	IL11RA
Domain Architecture	No domain graphic available
Description	Interleukin-11 receptor alpha chain precursor (IL-11R-alpha) (IL- 11RA).

FGR_MOUSE
NC score	0.089350 (rank : 514)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	207	Target Neighborhood Hits	1069	Shared Neighborhood Hits	52
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

ABL1_HUMAN
NC score	0.089126 (rank : 515)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	207	Target Neighborhood Hits	1220	Shared Neighborhood Hits	52
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

TRI42_HUMAN
NC score	0.089026 (rank : 516)	θ value	0.279714 (rank : 158)
Query Neighborhood Hits	207	Target Neighborhood Hits	283	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

ABL2_HUMAN
NC score	0.088837 (rank : 517)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	207	Target Neighborhood Hits	1045	Shared Neighborhood Hits	50
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

SRC_MOUSE
NC score	0.088822 (rank : 518)	θ value	θ > 10 (rank : 796)
Query Neighborhood Hits	207	Target Neighborhood Hits	1033	Shared Neighborhood Hits	52
SwissProt Accessions	P05480	Gene names	Src
Domain Architecture
Description	Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c-Src) (pp60c-src).

LRRC4_HUMAN
NC score	0.088659 (rank : 519)	θ value	θ > 10 (rank : 559)
Query Neighborhood Hits	207	Target Neighborhood Hits	444	Shared Neighborhood Hits	71
SwissProt Accessions	Q9HBW1, Q6ZMI8, Q96A85	Gene names	LRRC4, BAG
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 4 precursor (Brain tumor- associated protein LRRC4) (NAG14).

SRC_HUMAN
NC score	0.088482 (rank : 520)	θ value	θ > 10 (rank : 795)
Query Neighborhood Hits	207	Target Neighborhood Hits	1058	Shared Neighborhood Hits	52
SwissProt Accessions	P12931, Q86VB9, Q9H5A8	Gene names	SRC, SRC1
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src).

PTK6_MOUSE
NC score	0.088380 (rank : 521)	θ value	θ > 10 (rank : 699)
Query Neighborhood Hits	207	Target Neighborhood Hits	1026	Shared Neighborhood Hits	51
SwissProt Accessions	Q64434	Gene names	Ptk6, Sik
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (SRC-related intestinal kinase).

NAGPA_HUMAN
NC score	0.088092 (rank : 522)	θ value	θ > 10 (rank : 629)
Query Neighborhood Hits	207	Target Neighborhood Hits	282	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

CSK_HUMAN
NC score	0.088080 (rank : 523)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	207	Target Neighborhood Hits	1009	Shared Neighborhood Hits	51
SwissProt Accessions	P41240, Q6FGZ6	Gene names	CSK
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase CYL).

PTN13_MOUSE
NC score	0.087300 (rank : 524)	θ value	θ > 10 (rank : 706)
Query Neighborhood Hits	207	Target Neighborhood Hits	426	Shared Neighborhood Hits	17
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

FYN_MOUSE
NC score	0.087271 (rank : 525)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	207	Target Neighborhood Hits	1073	Shared Neighborhood Hits	51
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

FCN1_MOUSE
NC score	0.086852 (rank : 526)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	207	Target Neighborhood Hits	173	Shared Neighborhood Hits	15
SwissProt Accessions	O70165	Gene names	Fcn1, Fcna
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

PTK6_HUMAN
NC score	0.086805 (rank : 527)	θ value	θ > 10 (rank : 698)
Query Neighborhood Hits	207	Target Neighborhood Hits	1020	Shared Neighborhood Hits	51
SwissProt Accessions	Q13882	Gene names	PTK6, BRK
Domain Architecture
Description	Tyrosine-protein kinase 6 (EC 2.7.10.2) (Breast tumor kinase) (Tyrosine-protein kinase BRK).

FYN_HUMAN
NC score	0.086766 (rank : 528)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	207	Target Neighborhood Hits	1078	Shared Neighborhood Hits	51
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

CSK_MOUSE
NC score	0.086664 (rank : 529)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	207	Target Neighborhood Hits	1009	Shared Neighborhood Hits	51
SwissProt Accessions	P41241, Q03143	Gene names	Csk
Domain Architecture
Description	Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein- tyrosine kinase MPK-2) (p50CSK).

SREC2_HUMAN
NC score	0.086423 (rank : 530)	θ value	θ > 10 (rank : 797)
Query Neighborhood Hits	207	Target Neighborhood Hits	645	Shared Neighborhood Hits	43
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC_HUMAN
NC score	0.086107 (rank : 531)	θ value	θ > 10 (rank : 799)
Query Neighborhood Hits	207	Target Neighborhood Hits	645	Shared Neighborhood Hits	39
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

JAK1_HUMAN
NC score	0.085735 (rank : 532)	θ value	θ > 10 (rank : 459)
Query Neighborhood Hits	207	Target Neighborhood Hits	858	Shared Neighborhood Hits	50
SwissProt Accessions	P23458	Gene names	JAK1, JAK1A
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

PTN13_HUMAN
NC score	0.085672 (rank : 533)	θ value	θ > 10 (rank : 705)
Query Neighborhood Hits	207	Target Neighborhood Hits	471	Shared Neighborhood Hits	16
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

FCN1_HUMAN
NC score	0.085533 (rank : 534)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	207	Target Neighborhood Hits	147	Shared Neighborhood Hits	15
SwissProt Accessions	O00602, Q92596	Gene names	FCN1
Domain Architecture
Description	Ficolin-1 precursor (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin A) (M-Ficolin).

JAK1_MOUSE
NC score	0.085425 (rank : 535)	θ value	θ > 10 (rank : 460)
Query Neighborhood Hits	207	Target Neighborhood Hits	854	Shared Neighborhood Hits	50
SwissProt Accessions	P52332, Q62126	Gene names	Jak1
Domain Architecture
Description	Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1).

OX2G_MOUSE
NC score	0.085325 (rank : 536)	θ value	θ > 10 (rank : 662)
Query Neighborhood Hits	207	Target Neighborhood Hits	105	Shared Neighborhood Hits	32
SwissProt Accessions	O54901, O54816, Q9JHD5	Gene names	Cd200, Mox2
Domain Architecture
Description	OX-2 membrane glycoprotein precursor (MRC OX-2 antigen) (CD200 antigen).

ILRL2_HUMAN
NC score	0.084379 (rank : 537)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	207	Target Neighborhood Hits	112	Shared Neighborhood Hits	45
SwissProt Accessions	Q9HB29, Q13525, Q45H74	Gene names	IL1RL2, IL1RRP2
Domain Architecture
Description	Interleukin-1 receptor-like 2 precursor (IL-1Rrp2) (Interleukin-1 receptor-related protein 2) (IL1R-rp2).

JAK2_HUMAN
NC score	0.084028 (rank : 538)	θ value	θ > 10 (rank : 461)
Query Neighborhood Hits	207	Target Neighborhood Hits	847	Shared Neighborhood Hits	50
SwissProt Accessions	O60674, O14636, O75297	Gene names	JAK2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

FCN2_HUMAN
NC score	0.083678 (rank : 539)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	207	Target Neighborhood Hits	122	Shared Neighborhood Hits	14
SwissProt Accessions	Q15485, Q9UC57	Gene names	FCN2
Domain Architecture
Description	Ficolin-2 precursor (Collagen/fibrinogen domain-containing protein 2) (Ficolin-B) (Ficolin B) (Serum lectin p35) (EBP-37) (Hucolin) (L- Ficolin).

JAK3_HUMAN
NC score	0.083626 (rank : 540)	θ value	θ > 10 (rank : 463)
Query Neighborhood Hits	207	Target Neighborhood Hits	827	Shared Neighborhood Hits	50
SwissProt Accessions	P52333, Q13259, Q13260, Q13611, Q9Y6S2	Gene names	JAK3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK).

LAG3_MOUSE
NC score	0.083549 (rank : 541)	θ value	θ > 10 (rank : 510)
Query Neighborhood Hits	207	Target Neighborhood Hits	117	Shared Neighborhood Hits	30
SwissProt Accessions	Q61790, Q0VBL2	Gene names	Lag3
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (CD223 antigen).

FCN3_HUMAN
NC score	0.083514 (rank : 542)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	207	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	O75636, Q6IBJ5, Q8WW86	Gene names	FCN3, HAKA1
Domain Architecture
Description	Ficolin-3 precursor (Collagen/fibrinogen domain-containing protein 3) (Collagen/fibrinogen domain-containing lectin 3 p35) (Hakata antigen).

I27RA_MOUSE
NC score	0.083300 (rank : 543)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	207	Target Neighborhood Hits	55	Shared Neighborhood Hits	30
SwissProt Accessions	O70394	Gene names	Il27ra, Tccr, Wsx1
Domain Architecture	No domain graphic available
Description	Interleukin-27 receptor alpha chain precursor (IL-27R-alpha) (WSX-1) (Type I T-cell cytokine receptor) (TCCR).

JAK2_MOUSE
NC score	0.083258 (rank : 544)	θ value	θ > 10 (rank : 462)
Query Neighborhood Hits	207	Target Neighborhood Hits	839	Shared Neighborhood Hits	50
SwissProt Accessions	Q62120, Q62124	Gene names	Jak2
Domain Architecture
Description	Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2).

IRAK3_MOUSE
NC score	0.083111 (rank : 545)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	207	Target Neighborhood Hits	628	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

TYK2_MOUSE
NC score	0.082681 (rank : 546)	θ value	θ > 10 (rank : 852)
Query Neighborhood Hits	207	Target Neighborhood Hits	850	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R117, O88431, Q8VE41	Gene names	Tyk2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

PVRL2_MOUSE
NC score	0.082604 (rank : 547)	θ value	θ > 10 (rank : 749)
Query Neighborhood Hits	207	Target Neighborhood Hits	242	Shared Neighborhood Hits	36
SwissProt Accessions	P32507, Q62096	Gene names	Pvrl2, Mph, Pvr, Pvs
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Murine herpesvirus entry protein B) (mHveB) (Nectin-2) (Poliovirus receptor homolog) (CD112 antigen).

SREC2_MOUSE
NC score	0.082600 (rank : 548)	θ value	θ > 10 (rank : 798)
Query Neighborhood Hits	207	Target Neighborhood Hits	605	Shared Neighborhood Hits	33
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

KRA57_HUMAN
NC score	0.082157 (rank : 549)	θ value	θ > 10 (rank : 497)
Query Neighborhood Hits	207	Target Neighborhood Hits	269	Shared Neighborhood Hits	17
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

SIGL7_HUMAN
NC score	0.082157 (rank : 550)	θ value	θ > 10 (rank : 787)
Query Neighborhood Hits	207	Target Neighborhood Hits	180	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y286, Q9NZQ1, Q9UJ86, Q9UJ87, Q9Y502	Gene names	SIGLEC7, AIRM1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 7 precursor (Siglec-7) (QA79 membrane protein) (Adhesion inhibitory receptor molecule 1) (AIRM-1) (p75) (D-siglec) (CDw328 antigen).

KR171_HUMAN
NC score	0.082099 (rank : 551)	θ value	θ > 10 (rank : 487)
Query Neighborhood Hits	207	Target Neighborhood Hits	144	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

TYK2_HUMAN
NC score	0.082064 (rank : 552)	θ value	θ > 10 (rank : 851)
Query Neighborhood Hits	207	Target Neighborhood Hits	841	Shared Neighborhood Hits	50
SwissProt Accessions	P29597, Q6QB10, Q96CH0	Gene names	TYK2
Domain Architecture
Description	Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2).

JAK3_MOUSE
NC score	0.081058 (rank : 553)	θ value	θ > 10 (rank : 464)
Query Neighborhood Hits	207	Target Neighborhood Hits	821	Shared Neighborhood Hits	50
SwissProt Accessions	Q62137, Q61746, Q61747	Gene names	Jak3
Domain Architecture
Description	Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3).

ILK_MOUSE
NC score	0.080732 (rank : 554)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	207	Target Neighborhood Hits	858	Shared Neighborhood Hits	50
SwissProt Accessions	O55222	Gene names	Ilk
Domain Architecture
Description	Integrin-linked protein kinase (EC 2.7.11.1).

ILK1_HUMAN
NC score	0.080680 (rank : 555)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	207	Target Neighborhood Hits	857	Shared Neighborhood Hits	50
SwissProt Accessions	Q13418	Gene names	ILK, ILK1
Domain Architecture
Description	Integrin-linked protein kinase 1 (EC 2.7.11.1) (ILK-1) (59 kDa serine/threonine-protein kinase) (p59ILK).

OX2G_HUMAN
NC score	0.080363 (rank : 556)	θ value	θ > 10 (rank : 661)
Query Neighborhood Hits	207	Target Neighborhood Hits	100	Shared Neighborhood Hits	30
SwissProt Accessions	P41217, Q6J2Q6, Q6PIQ4, Q8TB85, Q9H3J3	Gene names	CD200, MOX2
Domain Architecture
Description	OX-2 membrane glycoprotein precursor (CD200 antigen).

IRAK3_HUMAN
NC score	0.080285 (rank : 557)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	207	Target Neighborhood Hits	644	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y616	Gene names	IRAK3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

ILK2_HUMAN
NC score	0.080021 (rank : 558)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	207	Target Neighborhood Hits	848	Shared Neighborhood Hits	50
SwissProt Accessions	P57043	Gene names	ILK2
Domain Architecture
Description	Integrin-linked protein kinase 2 (EC 2.7.11.1) (ILK-2).

KRA54_HUMAN
NC score	0.079940 (rank : 559)	θ value	θ > 10 (rank : 494)
Query Neighborhood Hits	207	Target Neighborhood Hits	270	Shared Neighborhood Hits	18
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

MLKL_HUMAN
NC score	0.079441 (rank : 560)	θ value	θ > 10 (rank : 608)
Query Neighborhood Hits	207	Target Neighborhood Hits	600	Shared Neighborhood Hits	46
SwissProt Accessions	Q8NB16, Q8N6V0	Gene names	MLKL
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

GUC2F_HUMAN
NC score	0.079301 (rank : 561)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	207	Target Neighborhood Hits	740	Shared Neighborhood Hits	49
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

KRA59_HUMAN
NC score	0.079045 (rank : 562)	θ value	θ > 10 (rank : 499)
Query Neighborhood Hits	207	Target Neighborhood Hits	310	Shared Neighborhood Hits	18
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA58_HUMAN
NC score	0.078962 (rank : 563)	θ value	θ > 10 (rank : 498)
Query Neighborhood Hits	207	Target Neighborhood Hits	324	Shared Neighborhood Hits	23
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

LAMA5_HUMAN
NC score	0.078921 (rank : 564)	θ value	θ > 10 (rank : 516)
Query Neighborhood Hits	207	Target Neighborhood Hits	976	Shared Neighborhood Hits	50
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

CD80_HUMAN
NC score	0.078887 (rank : 565)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	207	Target Neighborhood Hits	129	Shared Neighborhood Hits	37
SwissProt Accessions	P33681	Gene names	CD80, CD28LG, CD28LG1, LAB7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (CTLA-4 counter-receptor B7.1) (B7) (BB1).

LAMA5_MOUSE
NC score	0.078251 (rank : 566)	θ value	θ > 10 (rank : 517)
Query Neighborhood Hits	207	Target Neighborhood Hits	828	Shared Neighborhood Hits	52
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

GUC2C_HUMAN
NC score	0.078246 (rank : 567)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	207	Target Neighborhood Hits	624	Shared Neighborhood Hits	46
SwissProt Accessions	P25092	Gene names	GUCY2C, GUC2C, STAR
Domain Architecture
Description	Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) (hSTAR).

MEGF9_HUMAN
NC score	0.077996 (rank : 568)	θ value	θ > 10 (rank : 599)
Query Neighborhood Hits	207	Target Neighborhood Hits	557	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SHPS1_HUMAN
NC score	0.077957 (rank : 569)	θ value	θ > 10 (rank : 779)
Query Neighborhood Hits	207	Target Neighborhood Hits	455	Shared Neighborhood Hits	44
SwissProt Accessions	P78324, O00683, O43799, Q8N517, Q8TAL8, Q9H0Z2, Q9UDX2, Q9UIJ6, Q9Y4U9	Gene names	SIRPA, BIT, MFR, MYD1, PTPNS1, SHPS1, SIRP
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type substrate 1 precursor (SHP substrate 1) (SHPS-1) (Inhibitory receptor SHPS-1) (Signal- regulatory protein alpha-1) (Sirp-alpha-1) (Sirp-alpha-2) (Sirp-alpha- 3) (MyD-1 antigen) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (Macrophage fusion receptor) (p84) (CD172a antigen).

RAF1_MOUSE
NC score	0.077918 (rank : 570)	θ value	θ > 10 (rank : 754)
Query Neighborhood Hits	207	Target Neighborhood Hits	886	Shared Neighborhood Hits	51
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

ARAF_MOUSE
NC score	0.077763 (rank : 571)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	207	Target Neighborhood Hits	874	Shared Neighborhood Hits	50
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

MFAP4_MOUSE
NC score	0.077677 (rank : 572)	θ value	θ > 10 (rank : 607)
Query Neighborhood Hits	207	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D1H9, Q5NCN1	Gene names	Mfap4
Domain Architecture	No domain graphic available
Description	Microfibril-associated glycoprotein 4 precursor.

MFAP4_HUMAN
NC score	0.077534 (rank : 573)	θ value	θ > 10 (rank : 606)
Query Neighborhood Hits	207	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	P55083, Q6P680	Gene names	MFAP4
Domain Architecture
Description	Microfibril-associated glycoprotein 4 precursor.

RAF1_HUMAN
NC score	0.077497 (rank : 574)	θ value	θ > 10 (rank : 753)
Query Neighborhood Hits	207	Target Neighborhood Hits	886	Shared Neighborhood Hits	50
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

LAG3_HUMAN
NC score	0.077424 (rank : 575)	θ value	θ > 10 (rank : 509)
Query Neighborhood Hits	207	Target Neighborhood Hits	129	Shared Neighborhood Hits	22
SwissProt Accessions	P18627	Gene names	LAG3, FDC
Domain Architecture
Description	Lymphocyte activation gene 3 protein precursor (LAG-3) (FDC protein) (CD223 antigen).

ARAF_HUMAN
NC score	0.077396 (rank : 576)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	207	Target Neighborhood Hits	924	Shared Neighborhood Hits	50
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

KRA51_HUMAN
NC score	0.077357 (rank : 577)	θ value	θ > 10 (rank : 491)
Query Neighborhood Hits	207	Target Neighborhood Hits	288	Shared Neighborhood Hits	16
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA53_HUMAN
NC score	0.077189 (rank : 578)	θ value	θ > 10 (rank : 493)
Query Neighborhood Hits	207	Target Neighborhood Hits	331	Shared Neighborhood Hits	23
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

BRAF1_HUMAN
NC score	0.077117 (rank : 579)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	207	Target Neighborhood Hits	883	Shared Neighborhood Hits	50
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

WIF1_HUMAN
NC score	0.076796 (rank : 580)	θ value	θ > 10 (rank : 882)
Query Neighborhood Hits	207	Target Neighborhood Hits	392	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

IL6RA_MOUSE
NC score	0.075920 (rank : 581)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	207	Target Neighborhood Hits	104	Shared Neighborhood Hits	38
SwissProt Accessions	P22272	Gene names	Il6ra, Il6r
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (CD126 antigen).

CRLF2_MOUSE
NC score	0.075690 (rank : 582)	θ value	8.99809 (rank : 198)
Query Neighborhood Hits	207	Target Neighborhood Hits	39	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CII9, Q9CRJ6, Q9JIE7, Q9JIQ7, Q9JJH8, Q9JMD5	Gene names	Crlf2, Crlm2, Tpte2, Tslpr
Domain Architecture
Description	Cytokine receptor-like factor 2 precursor (Type I cytokine receptor delta 1) (Cytokine receptor-like molecule 2) (CRLM-2) (Thymic stromal lymphopoietin protein receptor) (TSLPR).

MLTK_MOUSE
NC score	0.075478 (rank : 583)	θ value	θ > 10 (rank : 611)
Query Neighborhood Hits	207	Target Neighborhood Hits	874	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ESL4, Q3V1X8, Q8BR73, Q9ESL3	Gene names	Mltk
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif kinase ZAK) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK).

MLTK_HUMAN
NC score	0.075330 (rank : 584)	θ value	θ > 10 (rank : 610)
Query Neighborhood Hits	207	Target Neighborhood Hits	911	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NYL2, Q53SX1, Q580W8, Q59GY5, Q86YW8, Q9HCC4, Q9HCC5, Q9HDD2, Q9NYE9	Gene names	MLTK, ZAK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase MLT (EC 2.7.11.25) (MLK-like mitogen-activated protein triple kinase) (Leucine zipper- and sterile alpha motif-containing kinase) (Sterile alpha motif- and leucine zipper-containing kinase AZK) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Cervical cancer suppressor gene 4 protein).

WIF1_MOUSE
NC score	0.074973 (rank : 585)	θ value	θ > 10 (rank : 883)
Query Neighborhood Hits	207	Target Neighborhood Hits	393	Shared Neighborhood Hits	21
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

PRPE_HUMAN
NC score	0.074971 (rank : 586)	θ value	θ > 10 (rank : 686)
Query Neighborhood Hits	207	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

EMB_HUMAN
NC score	0.074567 (rank : 587)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	207	Target Neighborhood Hits	54	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PCB8	Gene names	EMB
Domain Architecture	No domain graphic available
Description	Embigin precursor.

M3KL4_HUMAN
NC score	0.074189 (rank : 588)	θ value	θ > 10 (rank : 585)
Query Neighborhood Hits	207	Target Neighborhood Hits	1087	Shared Neighborhood Hits	53
SwissProt Accessions	Q5TCX8, Q5TCX7, Q5TCX9, Q8WWN1, Q8WWN2, Q96JM1	Gene names	MLK4, KIAA1804
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase (EC 2.7.11.25) (Mixed lineage kinase 4).

MLKL_MOUSE
NC score	0.074179 (rank : 589)	θ value	θ > 10 (rank : 609)
Query Neighborhood Hits	207	Target Neighborhood Hits	707	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D2Y4, Q8CIJ5	Gene names	Mlkl
Domain Architecture	No domain graphic available
Description	Mixed lineage kinase domain-like protein.

SIRB1_HUMAN
NC score	0.074109 (rank : 590)	θ value	θ > 10 (rank : 789)
Query Neighborhood Hits	207	Target Neighborhood Hits	422	Shared Neighborhood Hits	38
SwissProt Accessions	O00241, Q5TFR0, Q8TB12, Q9H1U5, Q9Y4V0	Gene names	SIRPB1
Domain Architecture
Description	Signal-regulatory protein beta-1 precursor (SIRP-beta-1) (CD172b antigen).

KR511_HUMAN
NC score	0.073731 (rank : 591)	θ value	θ > 10 (rank : 489)
Query Neighborhood Hits	207	Target Neighborhood Hits	231	Shared Neighborhood Hits	15
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

M3K10_HUMAN
NC score	0.073627 (rank : 592)	θ value	θ > 10 (rank : 577)
Query Neighborhood Hits	207	Target Neighborhood Hits	1071	Shared Neighborhood Hits	53
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

PRLR_HUMAN
NC score	0.073309 (rank : 593)	θ value	θ > 10 (rank : 684)
Query Neighborhood Hits	207	Target Neighborhood Hits	95	Shared Neighborhood Hits	38
SwissProt Accessions	P16471, Q16354, Q9BX87	Gene names	PRLR
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

LRRC4_MOUSE
NC score	0.073277 (rank : 594)	θ value	θ > 10 (rank : 560)
Query Neighborhood Hits	207	Target Neighborhood Hits	412	Shared Neighborhood Hits	66
SwissProt Accessions	Q99PH1, Q8VI35	Gene names	Lrrc4
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing 4 protein precursor (Brain tumor- associated protein MBAG1).

M3K12_HUMAN
NC score	0.073052 (rank : 595)	θ value	θ > 10 (rank : 579)
Query Neighborhood Hits	207	Target Neighborhood Hits	940	Shared Neighborhood Hits	52
SwissProt Accessions	Q12852, Q86VQ5, Q8WY25	Gene names	MAP3K12, ZPK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

M3K12_MOUSE
NC score	0.073024 (rank : 596)	θ value	θ > 10 (rank : 580)
Query Neighborhood Hits	207	Target Neighborhood Hits	957	Shared Neighborhood Hits	52
SwissProt Accessions	Q60700, P70286, Q3TLL7, Q8C4N7, Q8CBX3, Q8CDL6	Gene names	Map3k12, Zpk
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Mixed lineage kinase) (Leucine-zipper protein kinase) (ZPK) (Dual leucine zipper bearing kinase) (DLK) (MAPK-upstream kinase) (MUK).

FCRLA_HUMAN
NC score	0.072924 (rank : 597)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	207	Target Neighborhood Hits	135	Shared Neighborhood Hits	21
SwissProt Accessions	Q7L513, Q5VXA1, Q5VXA2, Q5VXA3, Q5VXB0, Q8NEW4, Q8WXH3, Q96PC6, Q96PJ0, Q96PJ1, Q96PJ2, Q96PJ4, Q9BR57	Gene names	FCRLA, FCRL, FCRL1, FCRLM1, FCRX, FREB
Domain Architecture	No domain graphic available
Description	Fc receptor-like and mucin-like 1 precursor (Fc receptor-like A) (Fc receptor homolog expressed in B-cells) (Fc receptor-related protein X) (FcRX) (Fc receptor-like protein).

M3K13_HUMAN
NC score	0.072880 (rank : 598)	θ value	θ > 10 (rank : 581)
Query Neighborhood Hits	207	Target Neighborhood Hits	911	Shared Neighborhood Hits	51
SwissProt Accessions	O43283	Gene names	MAP3K13, LZK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 13 (EC 2.7.11.25) (Mixed lineage kinase) (MLK) (Leucine zipper-bearing kinase).

ILRL1_MOUSE
NC score	0.072850 (rank : 599)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	207	Target Neighborhood Hits	172	Shared Neighborhood Hits	42
SwissProt Accessions	P14719, Q05208	Gene names	Il1rl1, Ly84, St2, Ste2
Domain Architecture
Description	Interleukin-1 receptor-like 1 precursor (ST2 protein) (T1 protein) (Lymphocyte antigen 84).

M3K9_HUMAN
NC score	0.072831 (rank : 600)	θ value	θ > 10 (rank : 584)
Query Neighborhood Hits	207	Target Neighborhood Hits	1123	Shared Neighborhood Hits	52
SwissProt Accessions	P80192, Q6EH31, Q9H2N5	Gene names	MAP3K9, MLK1, PRKE1
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1).

M3K7_MOUSE
NC score	0.072669 (rank : 601)	θ value	θ > 10 (rank : 583)
Query Neighborhood Hits	207	Target Neighborhood Hits	892	Shared Neighborhood Hits	50
SwissProt Accessions	Q62073	Gene names	Map3k7, Tak1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

LIMK2_MOUSE
NC score	0.072570 (rank : 602)	θ value	θ > 10 (rank : 536)
Query Neighborhood Hits	207	Target Neighborhood Hits	998	Shared Neighborhood Hits	50
SwissProt Accessions	O54785, O54776, O55238, Q9QUL4	Gene names	Limk2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

M3K7_HUMAN
NC score	0.072522 (rank : 603)	θ value	θ > 10 (rank : 582)
Query Neighborhood Hits	207	Target Neighborhood Hits	892	Shared Neighborhood Hits	50
SwissProt Accessions	O43318, O43317, O43319, Q5TDN2, Q5TDN3	Gene names	MAP3K7, TAK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta- activated kinase 1).

KRA56_HUMAN
NC score	0.072496 (rank : 604)	θ value	θ > 10 (rank : 496)
Query Neighborhood Hits	207	Target Neighborhood Hits	207	Shared Neighborhood Hits	16
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

RIPK3_HUMAN
NC score	0.072483 (rank : 605)	θ value	θ > 10 (rank : 764)
Query Neighborhood Hits	207	Target Neighborhood Hits	828	Shared Neighborhood Hits	53
SwissProt Accessions	Q9Y572	Gene names	RIPK3, RIP3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3).

LIMK2_HUMAN
NC score	0.072163 (rank : 606)	θ value	θ > 10 (rank : 535)
Query Neighborhood Hits	207	Target Neighborhood Hits	986	Shared Neighborhood Hits	50
SwissProt Accessions	P53671, Q7KZ80, Q96E10, Q99464	Gene names	LIMK2
Domain Architecture
Description	LIM domain kinase 2 (EC 2.7.11.1) (LIMK-2).

PVRL2_HUMAN
NC score	0.072070 (rank : 607)	θ value	θ > 10 (rank : 748)
Query Neighborhood Hits	207	Target Neighborhood Hits	185	Shared Neighborhood Hits	33
SwissProt Accessions	Q92692, O75455, Q96J29	Gene names	PVRL2, HVEB, PRR2
Domain Architecture
Description	Poliovirus receptor-related protein 2 precursor (Herpes virus entry mediator B) (HveB) (Nectin-2) (CD112 antigen).

MEGF6_HUMAN
NC score	0.072019 (rank : 608)	θ value	θ > 10 (rank : 596)
Query Neighborhood Hits	207	Target Neighborhood Hits	671	Shared Neighborhood Hits	46
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

M3K11_HUMAN
NC score	0.072014 (rank : 609)	θ value	θ > 10 (rank : 578)
Query Neighborhood Hits	207	Target Neighborhood Hits	1136	Shared Neighborhood Hits	55
SwissProt Accessions	Q16584, Q6P2G4	Gene names	MAP3K11, MLK3, SPRK
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline- rich kinase).

PDL2_HUMAN
NC score	0.071973 (rank : 610)	θ value	θ > 10 (rank : 668)
Query Neighborhood Hits	207	Target Neighborhood Hits	114	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BQ51, Q5T7Z6, Q6JXL8, Q6JXL9	Gene names	PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Domain Architecture	No domain graphic available
Description	Programmed cell death 1 ligand 2 precursor (Programmed death ligand 2) (PD-L2) (PD-1-ligand 2) (PDCD1 ligand 2) (Butyrophilin B7-DC) (B7-DC) (CD273 antigen).

FCGR1_MOUSE
NC score	0.071957 (rank : 611)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	207	Target Neighborhood Hits	123	Shared Neighborhood Hits	35
SwissProt Accessions	P26151	Gene names	Fcgr1, Fcg1
Domain Architecture
Description	High affinity immunoglobulin gamma Fc receptor I precursor (Fc-gamma RI) (FcRI) (IgG Fc receptor I).

TEX14_HUMAN
NC score	0.071834 (rank : 612)	θ value	θ > 10 (rank : 831)
Query Neighborhood Hits	207	Target Neighborhood Hits	1103	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

ANGL7_MOUSE
NC score	0.071810 (rank : 613)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	207	Target Neighborhood Hits	81	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R1Q3	Gene names	Angptl7
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7).

ANGL6_MOUSE
NC score	0.071610 (rank : 614)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	207	Target Neighborhood Hits	63	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R0Z6	Gene names	Angptl6, Agf
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor).

ANGL7_HUMAN
NC score	0.071450 (rank : 615)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	207	Target Neighborhood Hits	74	Shared Neighborhood Hits	7
SwissProt Accessions	O43827, Q4ZGK4	Gene names	ANGPTL7, CDT6
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 7 precursor (Angiopoietin-like 7) (Angiopoietin-like factor) (Cornea-derived transcript 6 protein).

MOS_HUMAN
NC score	0.071343 (rank : 616)	θ value	θ > 10 (rank : 612)
Query Neighborhood Hits	207	Target Neighborhood Hits	829	Shared Neighborhood Hits	50
SwissProt Accessions	P00540	Gene names	MOS
Domain Architecture
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

TESK2_MOUSE
NC score	0.071212 (rank : 617)	θ value	θ > 10 (rank : 830)
Query Neighborhood Hits	207	Target Neighborhood Hits	833	Shared Neighborhood Hits	50
SwissProt Accessions	Q8VCT9	Gene names	Tesk2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

TESK2_HUMAN
NC score	0.071194 (rank : 618)	θ value	θ > 10 (rank : 829)
Query Neighborhood Hits	207	Target Neighborhood Hits	851	Shared Neighborhood Hits	50
SwissProt Accessions	Q96S53, Q8N520, Q9Y3Q6	Gene names	TESK2
Domain Architecture
Description	Dual specificity testis-specific protein kinase 2 (EC 2.7.12.1) (Testicular protein kinase 2).

RIPK2_MOUSE
NC score	0.071099 (rank : 619)	θ value	θ > 10 (rank : 763)
Query Neighborhood Hits	207	Target Neighborhood Hits	776	Shared Neighborhood Hits	49
SwissProt Accessions	P58801	Gene names	Ripk2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1).

FGL1_HUMAN
NC score	0.071010 (rank : 620)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	207	Target Neighborhood Hits	49	Shared Neighborhood Hits	7
SwissProt Accessions	Q08830, Q4PJH9, Q96KW6, Q96QM6	Gene names	FGL1, HFREP1
Domain Architecture
Description	Fibrinogen-like protein 1 precursor (Hepatocyte-derived fibrinogen- related protein 1) (HFREP-1) (Hepassocin) (HP-041).

GUC2E_MOUSE
NC score	0.070850 (rank : 621)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	207	Target Neighborhood Hits	692	Shared Neighborhood Hits	48
SwissProt Accessions	P52785	Gene names	Gucy2e, Guc2e
Domain Architecture
Description	Guanylyl cyclase GC-E precursor (EC 4.6.1.2) (Guanylate cyclase 2E).

ANGL6_HUMAN
NC score	0.070378 (rank : 622)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	207	Target Neighborhood Hits	70	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NI99, Q9BZZ0	Gene names	ANGPTL6, AGF, ARP5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 6 precursor (Angiopoietin-like 6) (Angiopoietin-related growth factor) (Angiopoietin-related protein 5).

FGL2_MOUSE
NC score	0.070298 (rank : 623)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	207	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	P12804	Gene names	Fgl2, Fiblp
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (Prothrombinase) (Cytotoxic T-lymphocyte-specific protein).

SIG12_MOUSE
NC score	0.070089 (rank : 624)	θ value	θ > 10 (rank : 783)
Query Neighborhood Hits	207	Target Neighborhood Hits	225	Shared Neighborhood Hits	44
SwissProt Accessions	Q91Y57	Gene names	Siglec12, Siglec5, Siglece, Siglecl1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 12 precursor (Siglec-12) (Sialic acid-binding Ig-like lectin-like 1) (Siglec-L1) (Sialic acid-binding Ig-like lectin 5) (Siglec-5) (mSiglec-E) (Myeloid inhibitory siglec) (MIS).

ANGL5_HUMAN
NC score	0.069972 (rank : 625)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	207	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	Q86XS5, Q86VR9	Gene names	ANGPTL5
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 5 precursor (Angiopoietin-like 5).

KRA52_HUMAN
NC score	0.069933 (rank : 626)	θ value	θ > 10 (rank : 492)
Query Neighborhood Hits	207	Target Neighborhood Hits	236	Shared Neighborhood Hits	16
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KSR1_HUMAN
NC score	0.069721 (rank : 627)	θ value	θ > 10 (rank : 504)
Query Neighborhood Hits	207	Target Neighborhood Hits	867	Shared Neighborhood Hits	49
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

LIMK1_HUMAN
NC score	0.069593 (rank : 628)	θ value	θ > 10 (rank : 533)
Query Neighborhood Hits	207	Target Neighborhood Hits	1005	Shared Neighborhood Hits	50
SwissProt Accessions	P53667, O15283, Q15820, Q15821, Q75MU3, Q9Y5Q1	Gene names	LIMK1, LIMK
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1).

MEGF9_MOUSE
NC score	0.069281 (rank : 629)	θ value	θ > 10 (rank : 600)
Query Neighborhood Hits	207	Target Neighborhood Hits	896	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

TESK1_MOUSE
NC score	0.069263 (rank : 630)	θ value	θ > 10 (rank : 828)
Query Neighborhood Hits	207	Target Neighborhood Hits	862	Shared Neighborhood Hits	51
SwissProt Accessions	O70146, O70147	Gene names	Tesk1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

TRI42_MOUSE
NC score	0.069084 (rank : 631)	θ value	8.99809 (rank : 207)
Query Neighborhood Hits	207	Target Neighborhood Hits	316	Shared Neighborhood Hits	40
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

RIPK2_HUMAN
NC score	0.069059 (rank : 632)	θ value	θ > 10 (rank : 762)
Query Neighborhood Hits	207	Target Neighborhood Hits	774	Shared Neighborhood Hits	48
SwissProt Accessions	O43353, Q6UWF0	Gene names	RIPK2, CARDIAK, RICK, RIP2
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (CARD-containing interleukin-1 beta-converting enzyme- associated kinase) (CARD-containing IL-1 beta ICE-kinase).

LIMK1_MOUSE
NC score	0.069018 (rank : 633)	θ value	θ > 10 (rank : 534)
Query Neighborhood Hits	207	Target Neighborhood Hits	1008	Shared Neighborhood Hits	50
SwissProt Accessions	P53668	Gene names	Limk1, Limk
Domain Architecture
Description	LIM domain kinase 1 (EC 2.7.11.1) (LIMK-1) (KIZ-1).

FGL2_HUMAN
NC score	0.068970 (rank : 634)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	207	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	Q14314	Gene names	FGL2
Domain Architecture
Description	Fibroleukin precursor (Fibrinogen-like protein 2) (pT49).

KSR1_MOUSE
NC score	0.068926 (rank : 635)	θ value	θ > 10 (rank : 505)
Query Neighborhood Hits	207	Target Neighborhood Hits	870	Shared Neighborhood Hits	53
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

FIBA_HUMAN
NC score	0.068838 (rank : 636)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	207	Target Neighborhood Hits	132	Shared Neighborhood Hits	9
SwissProt Accessions	P02671, Q9BX62, Q9UCH2	Gene names	FGA
Domain Architecture
Description	Fibrinogen alpha chain precursor [Contains: Fibrinopeptide A].

ANPRA_MOUSE
NC score	0.068456 (rank : 637)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	207	Target Neighborhood Hits	600	Shared Neighborhood Hits	45
SwissProt Accessions	P18293	Gene names	Npr1, Npra
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

TESK1_HUMAN
NC score	0.068084 (rank : 638)	θ value	θ > 10 (rank : 827)
Query Neighborhood Hits	207	Target Neighborhood Hits	864	Shared Neighborhood Hits	50
SwissProt Accessions	Q15569	Gene names	TESK1
Domain Architecture
Description	Dual specificity testis-specific protein kinase 1 (EC 2.7.12.1) (Testicular protein kinase 1).

FIBB_MOUSE
NC score	0.067582 (rank : 639)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	207	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K0E8, Q91ZP1	Gene names	Fgb
Domain Architecture	No domain graphic available
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

ICAM1_MOUSE
NC score	0.067493 (rank : 640)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	207	Target Neighborhood Hits	99	Shared Neighborhood Hits	31
SwissProt Accessions	P13597, Q61828	Gene names	Icam1, Icam-1
Domain Architecture
Description	Intercellular adhesion molecule 1 precursor (ICAM-1) (MALA-2).

KRA55_HUMAN
NC score	0.067333 (rank : 641)	θ value	θ > 10 (rank : 495)
Query Neighborhood Hits	207	Target Neighborhood Hits	257	Shared Neighborhood Hits	17
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

FIBB_HUMAN
NC score	0.067319 (rank : 642)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	207	Target Neighborhood Hits	101	Shared Neighborhood Hits	7
SwissProt Accessions	P02675	Gene names	FGB
Domain Architecture
Description	Fibrinogen beta chain precursor [Contains: Fibrinopeptide B].

IRAK4_HUMAN
NC score	0.066732 (rank : 643)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	207	Target Neighborhood Hits	816	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NWZ3, Q8TDF7, Q9Y589	Gene names	IRAK4
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (IRAK-4) (NY- REN-64 antigen).

ANGL2_HUMAN
NC score	0.066681 (rank : 644)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	207	Target Neighborhood Hits	104	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKU9, Q5JT58	Gene names	ANGPTL2, ARP2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

ANGL2_MOUSE
NC score	0.066634 (rank : 645)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	207	Target Neighborhood Hits	108	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R045	Gene names	Angptl2, Arp2
Domain Architecture
Description	Angiopoietin-related protein 2 precursor (Angiopoietin-like 2).

GUC2D_HUMAN
NC score	0.066534 (rank : 646)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	207	Target Neighborhood Hits	715	Shared Neighborhood Hits	48
SwissProt Accessions	Q02846, Q6LEA7	Gene names	GUCY2D, CORD6, GUC1A4, GUC2D, RETGC, RETGC1
Domain Architecture
Description	Retinal guanylyl cyclase 1 precursor (EC 4.6.1.2) (Guanylate cyclase 2D, retinal) (RETGC-1) (Rod outer segment membrane guanylate cyclase) (ROS-GC).

TPSNR_MOUSE
NC score	0.066235 (rank : 647)	θ value	θ > 10 (rank : 845)
Query Neighborhood Hits	207	Target Neighborhood Hits	336	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VD31	Gene names	Tapbpl
Domain Architecture	No domain graphic available
Description	Tapasin-related protein precursor (TAPASIN-R) (Tapasin-like) (TAP- binding protein-related protein) (TAPBP-R) (TAP-binding protein-like).

ANGL1_MOUSE
NC score	0.066220 (rank : 648)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	207	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	Q640P2, Q3UQL1, Q9CZ81	Gene names	Angptl1
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 1 precursor (Angiopoietin-like 1).

MFAP3_HUMAN
NC score	0.066042 (rank : 649)	θ value	θ > 10 (rank : 605)
Query Neighborhood Hits	207	Target Neighborhood Hits	91	Shared Neighborhood Hits	32
SwissProt Accessions	P55082, Q9NXA7	Gene names	MFAP3
Domain Architecture
Description	Microfibril-associated glycoprotein 3 precursor.

CD4_HUMAN
NC score	0.066040 (rank : 650)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	207	Target Neighborhood Hits	122	Shared Neighborhood Hits	21
SwissProt Accessions	P01730, Q4ZGK2, Q5U066	Gene names	CD4
Domain Architecture
Description	T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3).

IRAK4_MOUSE
NC score	0.066017 (rank : 651)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	207	Target Neighborhood Hits	820	Shared Neighborhood Hits	51
SwissProt Accessions	Q8R4K2, Q80WW1	Gene names	Irak4
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 4 (EC 2.7.11.1) (IRAK-4).

IL27B_MOUSE
NC score	0.065883 (rank : 652)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	207	Target Neighborhood Hits	55	Shared Neighborhood Hits	29
SwissProt Accessions	O35228	Gene names	Ebi3, Il17b
Domain Architecture
Description	Interleukin-27 beta chain precursor (IL-27B) (Epstein-Barr virus- induced gene 3 protein homolog).

ANGL1_HUMAN
NC score	0.065851 (rank : 653)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	207	Target Neighborhood Hits	86	Shared Neighborhood Hits	7
SwissProt Accessions	O95841, Q5T5Z5	Gene names	ANGPTL1, ANG3, ANGPT3, ARP1
Domain Architecture	No domain graphic available
Description	Angiopoietin-related protein 1 precursor (Angiopoietin-like 1) (Angiopoietin-3) (ANG-3).

LAMB3_MOUSE
NC score	0.065781 (rank : 654)	θ value	θ > 10 (rank : 523)
Query Neighborhood Hits	207	Target Neighborhood Hits	444	Shared Neighborhood Hits	15
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

ANGP4_HUMAN
NC score	0.065472 (rank : 655)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	207	Target Neighborhood Hits	187	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y264, Q9H4Z4	Gene names	ANGPT4, ANG3, ANG4
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

ITB2_MOUSE
NC score	0.065411 (rank : 656)	θ value	θ > 10 (rank : 443)
Query Neighborhood Hits	207	Target Neighborhood Hits	326	Shared Neighborhood Hits	29
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ANPRA_HUMAN
NC score	0.065260 (rank : 657)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	207	Target Neighborhood Hits	612	Shared Neighborhood Hits	45
SwissProt Accessions	P16066, Q6P4Q3	Gene names	NPR1, ANPRA
Domain Architecture
Description	Atrial natriuretic peptide receptor A precursor (ANP-A) (ANPRA) (GC-A) (Guanylate cyclase) (EC 4.6.1.2) (NPR-A) (Atrial natriuretic peptide A-type receptor).

LAMB2_HUMAN
NC score	0.064884 (rank : 658)	θ value	θ > 10 (rank : 520)
Query Neighborhood Hits	207	Target Neighborhood Hits	692	Shared Neighborhood Hits	38
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

ANGL4_MOUSE
NC score	0.064674 (rank : 659)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	207	Target Neighborhood Hits	64	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z1P8, Q78ZJ9, Q9JHX7, Q9JLX7	Gene names	Angptl4, Farp, Fiaf, Ng27
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP) (Fasting- induced adipose factor) (Secreted protein Bk89) (425O18-1).

ITB6_MOUSE
NC score	0.064385 (rank : 660)	θ value	θ > 10 (rank : 449)
Query Neighborhood Hits	207	Target Neighborhood Hits	341	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

LAMB3_HUMAN
NC score	0.064354 (rank : 661)	θ value	θ > 10 (rank : 522)
Query Neighborhood Hits	207	Target Neighborhood Hits	461	Shared Neighborhood Hits	16
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

CD80_MOUSE
NC score	0.064221 (rank : 662)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	207	Target Neighborhood Hits	136	Shared Neighborhood Hits	27
SwissProt Accessions	Q00609, Q61332	Gene names	Cd80, B7
Domain Architecture
Description	T-lymphocyte activation antigen CD80 precursor (Activation B7-1 antigen) (B7).

ITB3_HUMAN
NC score	0.064188 (rank : 663)	θ value	θ > 10 (rank : 444)
Query Neighborhood Hits	207	Target Neighborhood Hits	325	Shared Neighborhood Hits	17
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ANGL4_HUMAN
NC score	0.064132 (rank : 664)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	207	Target Neighborhood Hits	79	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BY76, Q53HQ6, Q53HU1, Q6UXN0, Q9HBV4, Q9NZU4, Q9Y5B3	Gene names	ANGPTL4, ARP4, HFARP, PGAR
Domain Architecture
Description	Angiopoietin-related protein 4 precursor (Angiopoietin-like 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP).

TEX14_MOUSE
NC score	0.064086 (rank : 665)	θ value	θ > 10 (rank : 832)
Query Neighborhood Hits	207	Target Neighborhood Hits	1333	Shared Neighborhood Hits	50
SwissProt Accessions	Q7M6U3, Q3UT36, Q5NC10, Q5NC11, Q8CGK1, Q8CGK2, Q99MV8	Gene names	Tex14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

RIPK1_HUMAN
NC score	0.063954 (rank : 666)	θ value	θ > 10 (rank : 760)
Query Neighborhood Hits	207	Target Neighborhood Hits	891	Shared Neighborhood Hits	50
SwissProt Accessions	Q13546, Q13180	Gene names	RIPK1, RIP
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

ITB8_HUMAN
NC score	0.063948 (rank : 667)	θ value	θ > 10 (rank : 452)
Query Neighborhood Hits	207	Target Neighborhood Hits	280	Shared Neighborhood Hits	20
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

IGSF2_HUMAN
NC score	0.063742 (rank : 668)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	207	Target Neighborhood Hits	208	Shared Neighborhood Hits	32
SwissProt Accessions	Q93033, Q15856	Gene names	IGSF2, CD101, EWI101, V7
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 2 precursor (Glu-Trp-Ile EWI motif- containing protein 101) (EWI-101) (Cell surface glycoprotein V7) (CD101 antigen).

PRLR_MOUSE
NC score	0.063704 (rank : 669)	θ value	θ > 10 (rank : 685)
Query Neighborhood Hits	207	Target Neighborhood Hits	82	Shared Neighborhood Hits	33
SwissProt Accessions	Q08501, P15212, P15213, Q62099	Gene names	Prlr
Domain Architecture
Description	Prolactin receptor precursor (PRL-R).

ANGP4_MOUSE
NC score	0.063671 (rank : 670)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	207	Target Neighborhood Hits	220	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVH6	Gene names	Angpt4, Agpt4, Ang3
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

RIPK1_MOUSE
NC score	0.063573 (rank : 671)	θ value	θ > 10 (rank : 761)
Query Neighborhood Hits	207	Target Neighborhood Hits	874	Shared Neighborhood Hits	50
SwissProt Accessions	Q60855, Q3U0J3, Q8CD90	Gene names	Ripk1, Rinp, Rip
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase RIP) (Cell death protein RIP) (Receptor-interacting protein).

TNI3K_MOUSE
NC score	0.063246 (rank : 672)	θ value	θ > 10 (rank : 840)
Query Neighborhood Hits	207	Target Neighborhood Hits	1079	Shared Neighborhood Hits	51
SwissProt Accessions	Q5GIG6, Q5GIG5	Gene names	Tnni3k, Cark
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

ANGL3_MOUSE
NC score	0.063209 (rank : 673)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	207	Target Neighborhood Hits	306	Shared Neighborhood Hits	8
SwissProt Accessions	Q9R182	Gene names	Angptl3
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3).

ITB2_HUMAN
NC score	0.063139 (rank : 674)	θ value	θ > 10 (rank : 442)
Query Neighborhood Hits	207	Target Neighborhood Hits	282	Shared Neighborhood Hits	29
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB6_HUMAN
NC score	0.063059 (rank : 675)	θ value	θ > 10 (rank : 448)
Query Neighborhood Hits	207	Target Neighborhood Hits	318	Shared Neighborhood Hits	17
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB5_HUMAN
NC score	0.063018 (rank : 676)	θ value	θ > 10 (rank : 446)
Query Neighborhood Hits	207	Target Neighborhood Hits	310	Shared Neighborhood Hits	21
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

TRIM1_MOUSE
NC score	0.062905 (rank : 677)	θ value	0.813845 (rank : 165)
Query Neighborhood Hits	207	Target Neighborhood Hits	361	Shared Neighborhood Hits	37
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

LAMA1_MOUSE
NC score	0.062553 (rank : 678)	θ value	θ > 10 (rank : 512)
Query Neighborhood Hits	207	Target Neighborhood Hits	838	Shared Neighborhood Hits	44
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMB2_MOUSE
NC score	0.062535 (rank : 679)	θ value	θ > 10 (rank : 521)
Query Neighborhood Hits	207	Target Neighborhood Hits	722	Shared Neighborhood Hits	34
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

TNI3K_HUMAN
NC score	0.062532 (rank : 680)	θ value	θ > 10 (rank : 839)
Query Neighborhood Hits	207	Target Neighborhood Hits	1084	Shared Neighborhood Hits	50
SwissProt Accessions	Q59H18, Q49AR1, Q6MZS9, Q9Y2V6	Gene names	TNNI3K, CARK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TNNI3K (EC 2.7.11.1) (TNNI3- interacting kinase) (Cardiac ankyrin repeat kinase).

TOPK_HUMAN
NC score	0.062488 (rank : 681)	θ value	θ > 10 (rank : 843)
Query Neighborhood Hits	207	Target Neighborhood Hits	605	Shared Neighborhood Hits	44
SwissProt Accessions	Q96KB5, Q9NPD9, Q9NYL7, Q9NZK6	Gene names	PBK, TOPK
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (MAPKK-like protein kinase) (Nori-3).

FPRP_MOUSE
NC score	0.062429 (rank : 682)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	207	Target Neighborhood Hits	116	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WV91	Gene names	Ptgfrn, Fprp
Domain Architecture
Description	Prostaglandin F2 receptor negative regulator precursor (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD315 antigen).

MOS_MOUSE
NC score	0.062399 (rank : 683)	θ value	θ > 10 (rank : 613)
Query Neighborhood Hits	207	Target Neighborhood Hits	833	Shared Neighborhood Hits	50
SwissProt Accessions	P00536	Gene names	Mos
Domain Architecture	No domain graphic available
Description	Proto-oncogene serine/threonine-protein kinase mos (EC 2.7.11.1) (c- mos) (Oocyte maturation factor mos).

ANGP1_HUMAN
NC score	0.062373 (rank : 684)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	207	Target Neighborhood Hits	254	Shared Neighborhood Hits	7
SwissProt Accessions	Q15389	Gene names	ANGPT1, KIAA0003
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

ANGP1_MOUSE
NC score	0.062280 (rank : 685)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	207	Target Neighborhood Hits	252	Shared Neighborhood Hits	7
SwissProt Accessions	O08538	Gene names	Angpt1, Agpt
Domain Architecture
Description	Angiopoietin-1 precursor (ANG-1).

ITB1_HUMAN
NC score	0.062145 (rank : 686)	θ value	θ > 10 (rank : 440)
Query Neighborhood Hits	207	Target Neighborhood Hits	298	Shared Neighborhood Hits	17
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

STAB1_MOUSE
NC score	0.062133 (rank : 687)	θ value	θ > 10 (rank : 806)
Query Neighborhood Hits	207	Target Neighborhood Hits	566	Shared Neighborhood Hits	40
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

IRAK1_HUMAN
NC score	0.062090 (rank : 688)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	207	Target Neighborhood Hits	820	Shared Neighborhood Hits	49
SwissProt Accessions	P51617, Q7Z5V4, Q96RL2	Gene names	IRAK1, IRAK
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1).

FIBG_MOUSE
NC score	0.061928 (rank : 689)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	207	Target Neighborhood Hits	67	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VCM7, Q8WUR3, Q91ZP0	Gene names	Fgg
Domain Architecture	No domain graphic available
Description	Fibrinogen gamma chain precursor.

TOPK_MOUSE
NC score	0.061914 (rank : 690)	θ value	θ > 10 (rank : 844)
Query Neighborhood Hits	207	Target Neighborhood Hits	618	Shared Neighborhood Hits	47
SwissProt Accessions	Q9JJ78, Q922V2, Q9D184	Gene names	Pbk, Topk
Domain Architecture	No domain graphic available
Description	T-lymphokine-activated killer cell-originated protein kinase (EC 2.7.12.2) (T-LAK cell-originated protein kinase) (PDZ-binding kinase).

KSR2_HUMAN
NC score	0.061715 (rank : 691)	θ value	θ > 10 (rank : 506)
Query Neighborhood Hits	207	Target Neighborhood Hits	920	Shared Neighborhood Hits	50
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

ITB5_MOUSE
NC score	0.061610 (rank : 692)	θ value	θ > 10 (rank : 447)
Query Neighborhood Hits	207	Target Neighborhood Hits	329	Shared Neighborhood Hits	16
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

FIBG_HUMAN
NC score	0.061578 (rank : 693)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	207	Target Neighborhood Hits	99	Shared Neighborhood Hits	7
SwissProt Accessions	P02679, P04469, P04470, Q96A14, Q96KJ3	Gene names	FGG
Domain Architecture
Description	Fibrinogen gamma chain precursor.

ITB3_MOUSE
NC score	0.061424 (rank : 694)	θ value	θ > 10 (rank : 445)
Query Neighborhood Hits	207	Target Neighborhood Hits	319	Shared Neighborhood Hits	15
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ACVL1_MOUSE
NC score	0.061421 (rank : 695)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	207	Target Neighborhood Hits	739	Shared Neighborhood Hits	45
SwissProt Accessions	Q61288, Q61289	Gene names	Acvrl1, Acvrlk1, Alk-1
Domain Architecture
Description	Serine/threonine-protein kinase receptor R3 precursor (EC 2.7.11.30) (SKR3) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I).

MOX2R_HUMAN
NC score	0.061372 (rank : 696)	θ value	θ > 10 (rank : 614)
Query Neighborhood Hits	207	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TD46, Q8TD44, Q8TD45, Q8TD52	Gene names	CD200R1, CD200R, CRTR2, MOX2R, OX2R
Domain Architecture	No domain graphic available
Description	Cell surface glycoprotein OX2 receptor precursor (CD200 cell surface glycoprotein receptor).

BTNL2_HUMAN
NC score	0.061224 (rank : 697)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	207	Target Neighborhood Hits	164	Shared Neighborhood Hits	37
SwissProt Accessions	Q9UIR0, O98261, Q5JYF9, Q5RIF8, Q5SP08, Q5SP09, Q5SRW3, Q5SRW4, Q5SU36, Q95HK0	Gene names	BTNL2
Domain Architecture	No domain graphic available
Description	Butyrophilin-like protein 2 precursor (BTL-II).

LRRK1_MOUSE
NC score	0.061176 (rank : 698)	θ value	θ > 10 (rank : 562)
Query Neighborhood Hits	207	Target Neighborhood Hits	1267	Shared Neighborhood Hits	54
SwissProt Accessions	Q3UHC2, Q3U476, Q66JQ4, Q6GQR9, Q6NZF5, Q6ZPI4, Q8BKP3, Q8BU93, Q8BUY0, Q8BVV2, Q8R085	Gene names	Lrrk1, Kiaa1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

IRAK1_MOUSE
NC score	0.061140 (rank : 699)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	207	Target Neighborhood Hits	784	Shared Neighborhood Hits	49
SwissProt Accessions	Q62406, Q6Y3Z5, Q6Y3Z6	Gene names	Irak1, Il1rak
Domain Architecture
Description	Interleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1) (IRAK) (Pelle-like protein kinase) (mPLK).

STAB2_MOUSE
NC score	0.061066 (rank : 700)	θ value	θ > 10 (rank : 808)
Query Neighborhood Hits	207	Target Neighborhood Hits	528	Shared Neighborhood Hits	42
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

MYLK2_HUMAN
NC score	0.061030 (rank : 701)	θ value	θ > 10 (rank : 624)
Query Neighborhood Hits	207	Target Neighborhood Hits	920	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

ITB1_MOUSE
NC score	0.060921 (rank : 702)	θ value	θ > 10 (rank : 441)
Query Neighborhood Hits	207	Target Neighborhood Hits	283	Shared Neighborhood Hits	15
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

IKKA_HUMAN
NC score	0.060625 (rank : 703)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	207	Target Neighborhood Hits	863	Shared Neighborhood Hits	50
SwissProt Accessions	O15111, O14666, Q13132, Q92467	Gene names	CHUK, IKKA
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase alpha subunit (EC 2.7.11.10) (I kappa-B kinase alpha) (IkBKA) (IKK-alpha) (IKK-A) (IkappaB kinase) (I-kappa-B kinase 1) (IKK1) (Conserved helix-loop- helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA).

FANK1_MOUSE
NC score	0.060544 (rank : 704)	θ value	0.0563607 (rank : 149)
Query Neighborhood Hits	207	Target Neighborhood Hits	325	Shared Neighborhood Hits	43
SwissProt Accessions	Q9DAM9, Q9CUA7	Gene names	Fank1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains 1 protein (Germ cell- specific gene 1 protein) (GSG1).

RIPK3_MOUSE
NC score	0.060525 (rank : 705)	θ value	θ > 10 (rank : 765)
Query Neighborhood Hits	207	Target Neighborhood Hits	867	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

GUC2G_MOUSE
NC score	0.060516 (rank : 706)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	207	Target Neighborhood Hits	644	Shared Neighborhood Hits	44
SwissProt Accessions	Q6TL19, Q8BWU7	Gene names	Gucy2g
Domain Architecture	No domain graphic available
Description	Guanylate cyclase 2G precursor (EC 4.6.1.2) (Guanylyl cyclase receptor G) (mGC-G).

STAB1_HUMAN
NC score	0.060339 (rank : 707)	θ value	θ > 10 (rank : 805)
Query Neighborhood Hits	207	Target Neighborhood Hits	546	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

FANK1_HUMAN
NC score	0.060334 (rank : 708)	θ value	0.0252991 (rank : 140)
Query Neighborhood Hits	207	Target Neighborhood Hits	326	Shared Neighborhood Hits	35
SwissProt Accessions	Q8TC84, Q6UXY9, Q6X7T6	Gene names	FANK1
Domain Architecture	No domain graphic available
Description	Fibronectin type 3 and ankyrin repeat domains protein 1.

LRRK1_HUMAN
NC score	0.060202 (rank : 709)	θ value	θ > 10 (rank : 561)
Query Neighborhood Hits	207	Target Neighborhood Hits	1237	Shared Neighborhood Hits	54
SwissProt Accessions	Q38SD2, Q6NVH5, Q6NYC0, Q6ZNL9, Q6ZNM9, Q96JN5, Q9H5S3	Gene names	LRRK1, KIAA1790
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1).

LAMC3_MOUSE
NC score	0.060150 (rank : 710)	θ value	θ > 10 (rank : 528)
Query Neighborhood Hits	207	Target Neighborhood Hits	624	Shared Neighborhood Hits	36
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

ANPRB_HUMAN
NC score	0.060070 (rank : 711)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	207	Target Neighborhood Hits	646	Shared Neighborhood Hits	44
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

STK16_HUMAN
NC score	0.059895 (rank : 712)	θ value	θ > 10 (rank : 809)
Query Neighborhood Hits	207	Target Neighborhood Hits	824	Shared Neighborhood Hits	50
SwissProt Accessions	O75716, Q96KI2, Q9UEN3, Q9UP78	Gene names	STK16, MPSK1, PKL12, TSF1
Domain Architecture
Description	Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Protein kinase PKL12) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (TGF-beta-stimulated factor 1) (TSF-1) (hPSK).

IKKA_MOUSE
NC score	0.059783 (rank : 713)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	207	Target Neighborhood Hits	867	Shared Neighborhood Hits	50
SwissProt Accessions	Q60680, Q80VU2, Q9D2X3	Gene names	Chuk, Ikka
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase alpha subunit (EC 2.7.11.10) (I kappa-B kinase alpha) (IkBKA) (IKK-alpha) (IKK-A) (IkappaB kinase) (I-kappa-B kinase 1) (IKK1) (Conserved helix-loop- helix ubiquitous kinase) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA).

ANPRB_MOUSE
NC score	0.059640 (rank : 714)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	207	Target Neighborhood Hits	607	Shared Neighborhood Hits	44
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

LAMA1_HUMAN
NC score	0.059474 (rank : 715)	θ value	θ > 10 (rank : 511)
Query Neighborhood Hits	207	Target Neighborhood Hits	804	Shared Neighborhood Hits	44
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

TGFR2_MOUSE
NC score	0.059389 (rank : 716)	θ value	θ > 10 (rank : 836)
Query Neighborhood Hits	207	Target Neighborhood Hits	748	Shared Neighborhood Hits	49
SwissProt Accessions	Q62312, Q63947	Gene names	Tgfbr2
Domain Architecture
Description	TGF-beta receptor type-2 precursor (EC 2.7.11.30) (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor).

NEK11_MOUSE
NC score	0.059253 (rank : 717)	θ value	θ > 10 (rank : 634)
Query Neighborhood Hits	207	Target Neighborhood Hits	875	Shared Neighborhood Hits	50
SwissProt Accessions	Q8C0Q4, Q8BLS6, Q8BW62	Gene names	Nek11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

STK16_MOUSE
NC score	0.059146 (rank : 718)	θ value	θ > 10 (rank : 810)
Query Neighborhood Hits	207	Target Neighborhood Hits	824	Shared Neighborhood Hits	50
SwissProt Accessions	O88697, Q9JMJ0, Q9JMJ1, Q9QX00	Gene names	Stk16, Edpk, Krct, Mpsk1, Pkl12, Tsf1
Domain Architecture
Description	Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Protein kinase PKL12) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (TGF-beta-stimulated factor 1) (TSF-1) (Protein kinase Krct).

IRAK2_HUMAN
NC score	0.059112 (rank : 719)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	207	Target Neighborhood Hits	714	Shared Neighborhood Hits	48
SwissProt Accessions	O43187	Gene names	IRAK2
Domain Architecture
Description	Interleukin-1 receptor-associated kinase-like 2 (IRAK-2).

LAMA3_MOUSE
NC score	0.059073 (rank : 720)	θ value	θ > 10 (rank : 515)
Query Neighborhood Hits	207	Target Neighborhood Hits	859	Shared Neighborhood Hits	34
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

TGFR2_HUMAN
NC score	0.059059 (rank : 721)	θ value	θ > 10 (rank : 835)
Query Neighborhood Hits	207	Target Neighborhood Hits	748	Shared Neighborhood Hits	48
SwissProt Accessions	P37173, Q15580, Q6DKT6, Q99474	Gene names	TGFBR2
Domain Architecture
Description	TGF-beta receptor type-2 precursor (EC 2.7.11.30) (TGF-beta receptor type II) (TGFR-2) (TGF-beta type II receptor).

ITB7_HUMAN
NC score	0.059012 (rank : 722)	θ value	θ > 10 (rank : 450)
Query Neighborhood Hits	207	Target Neighborhood Hits	290	Shared Neighborhood Hits	17
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

LAMB1_MOUSE
NC score	0.058957 (rank : 723)	θ value	θ > 10 (rank : 519)
Query Neighborhood Hits	207	Target Neighborhood Hits	919	Shared Neighborhood Hits	28
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

ANGP2_HUMAN
NC score	0.058939 (rank : 724)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	207	Target Neighborhood Hits	400	Shared Neighborhood Hits	7
SwissProt Accessions	O15123, Q9NRR7, Q9P2Y7	Gene names	ANGPT2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

ANGL3_HUMAN
NC score	0.058751 (rank : 725)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	207	Target Neighborhood Hits	289	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5C1	Gene names	ANGPTL3, ANGPT5
Domain Architecture
Description	Angiopoietin-related protein 3 precursor (Angiopoietin-like 3) (Angiopoietin-5) (ANG-5).

ACVL1_HUMAN
NC score	0.058626 (rank : 726)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	207	Target Neighborhood Hits	716	Shared Neighborhood Hits	44
SwissProt Accessions	P37023	Gene names	ACVRL1, ACVRLK1, ALK1
Domain Architecture
Description	Serine/threonine-protein kinase receptor R3 precursor (EC 2.7.11.30) (SKR3) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I).

LAMC3_HUMAN
NC score	0.058343 (rank : 727)	θ value	θ > 10 (rank : 527)
Query Neighborhood Hits	207	Target Neighborhood Hits	588	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

ANGP2_MOUSE
NC score	0.058295 (rank : 728)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	207	Target Neighborhood Hits	397	Shared Neighborhood Hits	7
SwissProt Accessions	O35608, Q3U1A1, Q9D2D2	Gene names	Angpt2, Agpt2
Domain Architecture
Description	Angiopoietin-2 precursor (ANG-2).

FPRP_HUMAN
NC score	0.058281 (rank : 729)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	207	Target Neighborhood Hits	130	Shared Neighborhood Hits	33
SwissProt Accessions	Q9P2B2, Q8N2K6	Gene names	PTGFRN, CD9P1, FPRP, KIAA1436
Domain Architecture
Description	Prostaglandin F2 receptor negative regulator precursor (Prostaglandin F2-alpha receptor regulatory protein) (Prostaglandin F2-alpha receptor-associated protein) (CD9 partner 1) (CD9P-1) (CD315 antigen).

NEK11_HUMAN
NC score	0.058220 (rank : 730)	θ value	θ > 10 (rank : 633)
Query Neighborhood Hits	207	Target Neighborhood Hits	1043	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

KR104_HUMAN
NC score	0.058131 (rank : 731)	θ value	θ > 10 (rank : 486)
Query Neighborhood Hits	207	Target Neighborhood Hits	313	Shared Neighborhood Hits	19
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

TGFR1_MOUSE
NC score	0.058032 (rank : 732)	θ value	θ > 10 (rank : 834)
Query Neighborhood Hits	207	Target Neighborhood Hits	753	Shared Neighborhood Hits	49
SwissProt Accessions	Q64729	Gene names	Tgfbr1
Domain Architecture
Description	TGF-beta receptor type-1 precursor (EC 2.7.11.30) (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (ESK2).

IKKB_MOUSE
NC score	0.058008 (rank : 733)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	207	Target Neighborhood Hits	984	Shared Neighborhood Hits	50
SwissProt Accessions	O88351, Q9R1J6	Gene names	Ikbkb, Ikkb
Domain Architecture
Description	Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB).

IKKB_HUMAN
NC score	0.057968 (rank : 734)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	207	Target Neighborhood Hits	980	Shared Neighborhood Hits	50
SwissProt Accessions	O14920, O75327	Gene names	IKBKB, IKKB
Domain Architecture
Description	Inhibitor of nuclear factor kappa B kinase subunit beta (EC 2.7.11.10) (I-kappa-B-kinase beta) (IkBKB) (IKK-beta) (IKK-B) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB).

TGFR1_HUMAN
NC score	0.057801 (rank : 735)	θ value	θ > 10 (rank : 833)
Query Neighborhood Hits	207	Target Neighborhood Hits	755	Shared Neighborhood Hits	49
SwissProt Accessions	P36897	Gene names	TGFBR1
Domain Architecture
Description	TGF-beta receptor type-1 precursor (EC 2.7.11.30) (TGF-beta receptor type I) (TGFR-1) (TGF-beta type I receptor) (Serine/threonine-protein kinase receptor R4) (SKR4) (Activin receptor-like kinase 5) (ALK-5).

ATRN_HUMAN
NC score	0.057689 (rank : 736)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	207	Target Neighborhood Hits	525	Shared Neighborhood Hits	27
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

JAG1_MOUSE
NC score	0.057375 (rank : 737)	θ value	θ > 10 (rank : 456)
Query Neighborhood Hits	207	Target Neighborhood Hits	518	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

CT195_MOUSE
NC score	0.057272 (rank : 738)	θ value	0.813845 (rank : 163)
Query Neighborhood Hits	207	Target Neighborhood Hits	15	Shared Neighborhood Hits	8
SwissProt Accessions	Q80WB0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf195 homolog.

ACV1C_HUMAN
NC score	0.057071 (rank : 739)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	207	Target Neighborhood Hits	709	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NER5, Q4ZFZ8, Q86UL1, Q86UL2, Q8TBG2	Gene names	ACVR1C, ALK7
Domain Architecture	No domain graphic available
Description	Activin receptor type 1C precursor (EC 2.7.11.30) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7).

VITRN_HUMAN
NC score	0.057026 (rank : 740)	θ value	θ > 10 (rank : 875)
Query Neighborhood Hits	207	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q6UXI7, Q6P7T3, Q96DT1	Gene names	VIT
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

ITB7_MOUSE
NC score	0.056989 (rank : 741)	θ value	θ > 10 (rank : 451)
Query Neighborhood Hits	207	Target Neighborhood Hits	277	Shared Neighborhood Hits	17
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

VITRN_MOUSE
NC score	0.056985 (rank : 742)	θ value	θ > 10 (rank : 876)
Query Neighborhood Hits	207	Target Neighborhood Hits	68	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VHI5, Q3TZ47, Q8BQ41, Q8K047, Q9CYZ1	Gene names	Vit
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

COCH_HUMAN
NC score	0.056964 (rank : 743)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	207	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	O43405	Gene names	COCH, COCH5B2
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

BMPR2_HUMAN
NC score	0.056803 (rank : 744)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	207	Target Neighborhood Hits	736	Shared Neighborhood Hits	46
SwissProt Accessions	Q13873, Q16569	Gene names	BMPR2, PPH1
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II).

MEGF8_MOUSE
NC score	0.056612 (rank : 745)	θ value	θ > 10 (rank : 598)
Query Neighborhood Hits	207	Target Neighborhood Hits	520	Shared Neighborhood Hits	30
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

STK24_MOUSE
NC score	0.056488 (rank : 746)	θ value	θ > 10 (rank : 812)
Query Neighborhood Hits	207	Target Neighborhood Hits	856	Shared Neighborhood Hits	50
SwissProt Accessions	Q99KH8	Gene names	Stk24
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1).

MST4_HUMAN
NC score	0.056429 (rank : 747)	θ value	θ > 10 (rank : 618)
Query Neighborhood Hits	207	Target Neighborhood Hits	852	Shared Neighborhood Hits	50
SwissProt Accessions	Q9P289, Q3ZB77, Q9BXC4	Gene names	MST4, MASK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4) (Serine/threonine-protein kinase MASK) (Mst3 and SOK1-related kinase).

MST4_MOUSE
NC score	0.056379 (rank : 748)	θ value	θ > 10 (rank : 619)
Query Neighborhood Hits	207	Target Neighborhood Hits	860	Shared Neighborhood Hits	50
SwissProt Accessions	Q99JT2	Gene names	Mst4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MST4 (EC 2.7.11.1) (STE20-like kinase MST4) (MST-4) (Mammalian STE20-like protein kinase 4).

COCH_MOUSE
NC score	0.056348 (rank : 749)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	207	Target Neighborhood Hits	51	Shared Neighborhood Hits	6
SwissProt Accessions	Q62507, Q3TAF5, Q9QWK6	Gene names	Coch
Domain Architecture
Description	Cochlin precursor (COCH-5B2).

ST17B_MOUSE
NC score	0.056264 (rank : 750)	θ value	θ > 10 (rank : 804)
Query Neighborhood Hits	207	Target Neighborhood Hits	838	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BG48, Q3TNG7, Q8BLV9, Q923E7	Gene names	Stk17b, Drak2
Domain Architecture
Description	Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2).

TRI18_HUMAN
NC score	0.056098 (rank : 751)	θ value	θ > 10 (rank : 846)
Query Neighborhood Hits	207	Target Neighborhood Hits	307	Shared Neighborhood Hits	42
SwissProt Accessions	O15344, O75361, Q9BZX5	Gene names	MID1, FXY, RNF59, TRIM18, XPRF
Domain Architecture
Description	Midline-1 (EC 6.3.2.-) (Tripartite motif-containing protein 18) (Putative transcription factor XPRF) (Midin) (RING finger protein 59) (Midline 1 RING finger protein).

IL6RA_HUMAN
NC score	0.056085 (rank : 752)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	207	Target Neighborhood Hits	96	Shared Neighborhood Hits	30
SwissProt Accessions	P08887, Q16202, Q53EQ7, Q5FWG2, Q5VZ23	Gene names	IL6R
Domain Architecture
Description	Interleukin-6 receptor alpha chain precursor (IL-6R-alpha) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD126 antigen).

STK24_HUMAN
NC score	0.056052 (rank : 753)	θ value	θ > 10 (rank : 811)
Query Neighborhood Hits	207	Target Neighborhood Hits	853	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y6E0, O14840	Gene names	STK24, MST3, STK3
Domain Architecture
Description	Serine/threonine-protein kinase 24 (EC 2.7.11.1) (STE20-like kinase MST3) (MST-3) (Mammalian STE20-like protein kinase 3).

MEGF8_HUMAN
NC score	0.056038 (rank : 754)	θ value	θ > 10 (rank : 597)
Query Neighborhood Hits	207	Target Neighborhood Hits	528	Shared Neighborhood Hits	32
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

STK33_HUMAN
NC score	0.055963 (rank : 755)	θ value	θ > 10 (rank : 815)
Query Neighborhood Hits	207	Target Neighborhood Hits	879	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BYT3, Q658S6, Q8NEF5	Gene names	STK33
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 33 (EC 2.7.11.1).

LAMA2_HUMAN
NC score	0.055916 (rank : 756)	θ value	θ > 10 (rank : 513)
Query Neighborhood Hits	207	Target Neighborhood Hits	1092	Shared Neighborhood Hits	45
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

ACV1B_MOUSE
NC score	0.055912 (rank : 757)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	207	Target Neighborhood Hits	753	Shared Neighborhood Hits	48
SwissProt Accessions	Q61271	Gene names	Acvr1b
Domain Architecture
Description	Activin receptor type 1B precursor (EC 2.7.11.30) (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2).

BT3A2_HUMAN
NC score	0.055782 (rank : 758)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	207	Target Neighborhood Hits	158	Shared Neighborhood Hits	30
SwissProt Accessions	P78410, O00477, O15338, O75658, Q76PA0, Q9BU81, Q9NR44	Gene names	BTN3A2, BT3.2, BTF3, BTF4
Domain Architecture	No domain graphic available
Description	Butyrophilin subfamily 3 member A2 precursor.

BMPR2_MOUSE
NC score	0.055741 (rank : 759)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	207	Target Neighborhood Hits	738	Shared Neighborhood Hits	46
SwissProt Accessions	O35607	Gene names	Bmpr2
Domain Architecture
Description	Bone morphogenetic protein receptor type-2 precursor (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II) (BRK-3).

DAPK2_MOUSE
NC score	0.055627 (rank : 760)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	207	Target Neighborhood Hits	834	Shared Neighborhood Hits	51
SwissProt Accessions	Q8VDF3, O88861, Q9QYM4	Gene names	Dapk2
Domain Architecture
Description	Death-associated protein kinase 2 (EC 2.7.11.1) (DAP kinase 2) (DAP- kinase-related protein 1) (DRP-1).

STK4_MOUSE
NC score	0.055606 (rank : 761)	θ value	θ > 10 (rank : 822)
Query Neighborhood Hits	207	Target Neighborhood Hits	873	Shared Neighborhood Hits	51
SwissProt Accessions	Q9JI11	Gene names	Stk4, Mst1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1).

LRP1_HUMAN
NC score	0.055574 (rank : 762)	θ value	6.88961 (rank : 194)
Query Neighborhood Hits	207	Target Neighborhood Hits	617	Shared Neighborhood Hits	40
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

ACV1B_HUMAN
NC score	0.055543 (rank : 763)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	207	Target Neighborhood Hits	753	Shared Neighborhood Hits	48
SwissProt Accessions	P36896, Q15479, Q15480, Q15481, Q15482	Gene names	ACVR1B, ACVRLK4
Domain Architecture
Description	Activin receptor type 1B precursor (EC 2.7.11.30) (ACTR-IB) (Serine/threonine-protein kinase receptor R2) (SKR2) (Activin receptor-like kinase 4) (ALK-4).

STAB2_HUMAN
NC score	0.055443 (rank : 764)	θ value	θ > 10 (rank : 807)
Query Neighborhood Hits	207	Target Neighborhood Hits	534	Shared Neighborhood Hits	35
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STK4_HUMAN
NC score	0.055374 (rank : 765)	θ value	θ > 10 (rank : 821)
Query Neighborhood Hits	207	Target Neighborhood Hits	870	Shared Neighborhood Hits	50
SwissProt Accessions	Q13043, Q15802, Q4G156, Q5H982, Q6PD60, Q9BR32, Q9NTZ4	Gene names	STK4, MST1
Domain Architecture
Description	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2).

DAPK3_HUMAN
NC score	0.055273 (rank : 766)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	207	Target Neighborhood Hits	945	Shared Neighborhood Hits	50
SwissProt Accessions	O43293	Gene names	DAPK3, ZIPK
Domain Architecture
Description	Death-associated protein kinase 3 (EC 2.7.11.1) (DAP kinase 3) (DAP- like kinase) (Dlk) (ZIP-kinase).

DAPK2_HUMAN
NC score	0.055256 (rank : 767)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	207	Target Neighborhood Hits	832	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UIK4, O75892	Gene names	DAPK2
Domain Architecture
Description	Death-associated protein kinase 2 (EC 2.7.11.1) (DAP kinase 2) (DAP- kinase-related protein 1) (DRP-1).

ICAM3_HUMAN
NC score	0.055247 (rank : 768)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	207	Target Neighborhood Hits	100	Shared Neighborhood Hits	35
SwissProt Accessions	P32942	Gene names	ICAM3
Domain Architecture
Description	Intercellular adhesion molecule 3 precursor (ICAM-3) (ICAM-R) (CDw50) (CD50 antigen).

LAMB1_HUMAN
NC score	0.055038 (rank : 769)	θ value	θ > 10 (rank : 518)
Query Neighborhood Hits	207	Target Neighborhood Hits	1018	Shared Neighborhood Hits	29
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

STK3_MOUSE
NC score	0.054959 (rank : 770)	θ value	θ > 10 (rank : 820)
Query Neighborhood Hits	207	Target Neighborhood Hits	869	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JI10, Q60877, Q80UG4, Q8CI58	Gene names	Stk3, Mess1, Mst2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2).

ACV1C_MOUSE
NC score	0.054905 (rank : 771)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	207	Target Neighborhood Hits	715	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K348	Gene names	Acvr1c, Alk7
Domain Architecture	No domain graphic available
Description	Activin receptor type 1C precursor (EC 2.7.11.30) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7).

DAPK3_MOUSE
NC score	0.054893 (rank : 772)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	207	Target Neighborhood Hits	843	Shared Neighborhood Hits	50
SwissProt Accessions	O54784	Gene names	Dapk3, Zipk
Domain Architecture
Description	Death-associated protein kinase 3 (EC 2.7.11.1) (DAP kinase 3) (DAP- like kinase) (Dlk) (ZIP-kinase).

FCRLA_MOUSE
NC score	0.054772 (rank : 773)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	207	Target Neighborhood Hits	110	Shared Neighborhood Hits	20
SwissProt Accessions	Q920A9, Q3T9Q2, Q8K3U9, Q8VHP5	Gene names	Fcrla, Fcrl, Fcrl1, Fcrlm1, Fcrx, Freb
Domain Architecture	No domain graphic available
Description	Fc receptor-like and mucin-like 1 precursor (Fc receptor-like A) (Fc receptor homolog expressed in B-cells) (Fc receptor-related protein X) (FcRX) (Fc receptor-like protein).

JAG1_HUMAN
NC score	0.054766 (rank : 774)	θ value	θ > 10 (rank : 455)
Query Neighborhood Hits	207	Target Neighborhood Hits	514	Shared Neighborhood Hits	22
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

LAMC1_MOUSE
NC score	0.054691 (rank : 775)	θ value	θ > 10 (rank : 525)
Query Neighborhood Hits	207	Target Neighborhood Hits	856	Shared Neighborhood Hits	36
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LRRK2_HUMAN
NC score	0.054597 (rank : 776)	θ value	θ > 10 (rank : 563)
Query Neighborhood Hits	207	Target Neighborhood Hits	1382	Shared Neighborhood Hits	53
SwissProt Accessions	Q5S007, Q6ZS50, Q8NCX9	Gene names	LRRK2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (Dardarin).

JAML1_HUMAN
NC score	0.054546 (rank : 777)	θ value	θ > 10 (rank : 471)
Query Neighborhood Hits	207	Target Neighborhood Hits	108	Shared Neighborhood Hits	21
SwissProt Accessions	Q86YT9, Q5DTC6, Q7Z499, Q8N9I7, Q8NF70	Gene names	AMICA1, JAML
Domain Architecture	No domain graphic available
Description	Junctional adhesion molecule-like precursor (Dendritic cell-specific protein CREA7-1) (Adhesion molecule interacting with CXADR antigen 1).

ATRN_MOUSE
NC score	0.054538 (rank : 778)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	207	Target Neighborhood Hits	519	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

STK3_HUMAN
NC score	0.054518 (rank : 779)	θ value	θ > 10 (rank : 819)
Query Neighborhood Hits	207	Target Neighborhood Hits	861	Shared Neighborhood Hits	50
SwissProt Accessions	Q13188, Q15445, Q15801, Q96FM6	Gene names	STK3, MST2
Domain Architecture
Description	Serine/threonine-protein kinase 3 (EC 2.7.11.1) (STE20-like kinase MST2) (MST-2) (Mammalian STE20-like protein kinase 2) (Serine/threonine-protein kinase Krs-1).

MP2K5_HUMAN
NC score	0.054318 (rank : 780)	θ value	θ > 10 (rank : 616)
Query Neighborhood Hits	207	Target Neighborhood Hits	837	Shared Neighborhood Hits	51
SwissProt Accessions	Q13163	Gene names	MAP2K5, MEK5, MKK5, PRKMK5
Domain Architecture
Description	Dual specificity mitogen-activated protein kinase kinase 5 (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5).

NEK7_MOUSE
NC score	0.054278 (rank : 781)	θ value	θ > 10 (rank : 640)
Query Neighborhood Hits	207	Target Neighborhood Hits	847	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ES74, Q3UEV7	Gene names	Nek7
Domain Architecture
Description	Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (NimA-related protein kinase 7).

JAG2_HUMAN
NC score	0.054090 (rank : 782)	θ value	θ > 10 (rank : 457)
Query Neighborhood Hits	207	Target Neighborhood Hits	491	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

NEK7_HUMAN
NC score	0.054038 (rank : 783)	θ value	θ > 10 (rank : 639)
Query Neighborhood Hits	207	Target Neighborhood Hits	846	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TDX7	Gene names	NEK7
Domain Architecture
Description	Serine/threonine-protein kinase Nek7 (EC 2.7.11.1) (NimA-related protein kinase 7).

JAG2_MOUSE
NC score	0.053845 (rank : 784)	θ value	θ > 10 (rank : 458)
Query Neighborhood Hits	207	Target Neighborhood Hits	504	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

NEK4_HUMAN
NC score	0.053736 (rank : 785)	θ value	θ > 10 (rank : 635)
Query Neighborhood Hits	207	Target Neighborhood Hits	883	Shared Neighborhood Hits	50
SwissProt Accessions	P51957	Gene names	NEK4, STK2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2) (Serine/threonine-protein kinase NRK2).

NEK4_MOUSE
NC score	0.053720 (rank : 786)	θ value	θ > 10 (rank : 636)
Query Neighborhood Hits	207	Target Neighborhood Hits	899	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z1J2, O35673, Q9R1J1	Gene names	Nek4, Stk2
Domain Architecture
Description	Serine/threonine-protein kinase Nek4 (EC 2.7.11.1) (NimA-related protein kinase 4) (Serine/threonine-protein kinase 2).

YSK4_HUMAN
NC score	0.053540 (rank : 787)	θ value	θ > 10 (rank : 886)
Query Neighborhood Hits	207	Target Neighborhood Hits	921	Shared Neighborhood Hits	51
SwissProt Accessions	Q56UN5, Q56UN1, Q56UN2, Q56UN3, Q56UN4, Q8N4E9, Q9H5T2	Gene names	YSK4, RCK
Domain Architecture	No domain graphic available
Description	SPS1/STE20-related protein kinase YSK4 (EC 2.7.11.1) (Regulated in COPD, protein kinase).

STK25_MOUSE
NC score	0.053516 (rank : 788)	θ value	θ > 10 (rank : 814)
Query Neighborhood Hits	207	Target Neighborhood Hits	851	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Z2W1	Gene names	Stk25, Sok1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

STK25_HUMAN
NC score	0.053506 (rank : 789)	θ value	θ > 10 (rank : 813)
Query Neighborhood Hits	207	Target Neighborhood Hits	853	Shared Neighborhood Hits	50
SwissProt Accessions	O00506, Q15522, Q5BJF1	Gene names	STK25, SOK1, YSK1
Domain Architecture
Description	Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Sterile 20/oxidant stress-response kinase 1) (Ste20/oxidant stress response kinase 1) (SOK-1) (Ste20-like kinase).

ST17B_HUMAN
NC score	0.053406 (rank : 790)	θ value	θ > 10 (rank : 803)
Query Neighborhood Hits	207	Target Neighborhood Hits	833	Shared Neighborhood Hits	46
SwissProt Accessions	O94768	Gene names	STK17B, DRAK2
Domain Architecture
Description	Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2).

MP2K5_MOUSE
NC score	0.053380 (rank : 791)	θ value	θ > 10 (rank : 617)
Query Neighborhood Hits	207	Target Neighborhood Hits	840	Shared Neighborhood Hits	51
SwissProt Accessions	Q9WVS7, Q8CFM3, Q8K360, Q9D222	Gene names	Map2k5, Mek5, Mkk5, Prkmk5
Domain Architecture	No domain graphic available
Description	Dual specificity mitogen-activated protein kinase kinase 5 (EC 2.7.12.2) (MAP kinase kinase 5) (MAPKK 5) (MAPK/ERK kinase 5).

LAMA2_MOUSE
NC score	0.053327 (rank : 792)	θ value	θ > 10 (rank : 514)
Query Neighborhood Hits	207	Target Neighborhood Hits	1198	Shared Neighborhood Hits	43
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

BMR1A_HUMAN
NC score	0.053187 (rank : 793)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	207	Target Neighborhood Hits	759	Shared Neighborhood Hits	48
SwissProt Accessions	P36894, Q8NEN8	Gene names	BMPR1A, ACVRLK3, ALK3
Domain Architecture
Description	Bone morphogenetic protein receptor type IA precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (CD292 antigen).

BMR1A_MOUSE
NC score	0.053173 (rank : 794)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	207	Target Neighborhood Hits	758	Shared Neighborhood Hits	48
SwissProt Accessions	P36895	Gene names	Bmpr1a, Acvrlk3, Bmpr
Domain Architecture
Description	Bone morphogenetic protein receptor type IA precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R5) (SKR5) (Activin receptor-like kinase 3) (ALK-3) (BMP-2/BMP-4 receptor).

DLK_HUMAN
NC score	0.053135 (rank : 795)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	207	Target Neighborhood Hits	401	Shared Neighborhood Hits	23
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLL4_MOUSE
NC score	0.053062 (rank : 796)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	207	Target Neighborhood Hits	440	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

ULK1_HUMAN
NC score	0.053007 (rank : 797)	θ value	θ > 10 (rank : 853)
Query Neighborhood Hits	207	Target Neighborhood Hits	1121	Shared Neighborhood Hits	54
SwissProt Accessions	O75385	Gene names	ULK1
Domain Architecture
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1).

ULK1_MOUSE
NC score	0.052884 (rank : 798)	θ value	θ > 10 (rank : 854)
Query Neighborhood Hits	207	Target Neighborhood Hits	1214	Shared Neighborhood Hits	56
SwissProt Accessions	O70405, Q6PGB2	Gene names	Ulk1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Unc-51-like kinase 1) (Serine/threonine-protein kinase Unc51.1).

RIPK4_HUMAN
NC score	0.052881 (rank : 799)	θ value	θ > 10 (rank : 766)
Query Neighborhood Hits	207	Target Neighborhood Hits	1094	Shared Neighborhood Hits	52
SwissProt Accessions	P57078, Q96KH0	Gene names	RIPK4, ANKRD3, DIK
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain protein 3) (PKC-delta-interacting protein kinase).

NEK6_HUMAN
NC score	0.052852 (rank : 800)	θ value	θ > 10 (rank : 637)
Query Neighborhood Hits	207	Target Neighborhood Hits	848	Shared Neighborhood Hits	50
SwissProt Accessions	Q9HC98, Q96E83, Q9ULX2	Gene names	NEK6
Domain Architecture
Description	Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (NimA-related protein kinase 6) (Protein kinase SID6-1512).

NEK6_MOUSE
NC score	0.052667 (rank : 801)	θ value	θ > 10 (rank : 638)
Query Neighborhood Hits	207	Target Neighborhood Hits	851	Shared Neighborhood Hits	50
SwissProt Accessions	Q9ES70, Q3TCE9, Q8C6E6, Q9D0E2, Q9DBI8	Gene names	Nek6
Domain Architecture
Description	Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (NimA-related protein kinase 6).

NTNG2_HUMAN
NC score	0.052663 (rank : 802)	θ value	θ > 10 (rank : 648)
Query Neighborhood Hits	207	Target Neighborhood Hits	276	Shared Neighborhood Hits	20
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

EGFL9_HUMAN
NC score	0.052656 (rank : 803)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	207	Target Neighborhood Hits	365	Shared Neighborhood Hits	23
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

LRP1B_MOUSE
NC score	0.052648 (rank : 804)	θ value	θ > 10 (rank : 558)
Query Neighborhood Hits	207	Target Neighborhood Hits	606	Shared Neighborhood Hits	30
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

EGFL9_MOUSE
NC score	0.052435 (rank : 805)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	207	Target Neighborhood Hits	379	Shared Neighborhood Hits	24
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

PAK6_HUMAN
NC score	0.052384 (rank : 806)	θ value	θ > 10 (rank : 663)
Query Neighborhood Hits	207	Target Neighborhood Hits	915	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NQU5	Gene names	PAK6, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (p21-activated kinase 6) (PAK-6) (PAK-5).

MATN1_MOUSE
NC score	0.052366 (rank : 807)	θ value	θ > 10 (rank : 594)
Query Neighborhood Hits	207	Target Neighborhood Hits	186	Shared Neighborhood Hits	7
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

ULK2_HUMAN
NC score	0.052297 (rank : 808)	θ value	θ > 10 (rank : 855)
Query Neighborhood Hits	207	Target Neighborhood Hits	979	Shared Neighborhood Hits	53
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

RIPK5_MOUSE
NC score	0.052283 (rank : 809)	θ value	θ > 10 (rank : 768)
Query Neighborhood Hits	207	Target Neighborhood Hits	874	Shared Neighborhood Hits	50
SwissProt Accessions	Q6XUX1, Q3ULK4, Q5EBN5, Q8C7D4, Q8C923, Q9CTP7	Gene names	Ripk5
Domain Architecture	No domain graphic available
Description	Receptor-interacting serine/threonine-protein kinase 5 (EC 2.7.11.1) (Dusty protein kinase) (Dusty PK).

STK36_MOUSE
NC score	0.052211 (rank : 810)	θ value	θ > 10 (rank : 817)
Query Neighborhood Hits	207	Target Neighborhood Hits	877	Shared Neighborhood Hits	50
SwissProt Accessions	Q69ZM6, Q6PDI0, Q80XQ6	Gene names	Stk36, Kiaa1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

KR510_HUMAN
NC score	0.052199 (rank : 811)	θ value	θ > 10 (rank : 488)
Query Neighborhood Hits	207	Target Neighborhood Hits	217	Shared Neighborhood Hits	15
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

VWF_HUMAN
NC score	0.052170 (rank : 812)	θ value	θ > 10 (rank : 880)
Query Neighborhood Hits	207	Target Neighborhood Hits	396	Shared Neighborhood Hits	30
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

MATN1_HUMAN
NC score	0.052157 (rank : 813)	θ value	θ > 10 (rank : 593)
Query Neighborhood Hits	207	Target Neighborhood Hits	191	Shared Neighborhood Hits	7
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

RIPK5_HUMAN
NC score	0.052092 (rank : 814)	θ value	θ > 10 (rank : 767)
Query Neighborhood Hits	207	Target Neighborhood Hits	864	Shared Neighborhood Hits	50
SwissProt Accessions	Q6XUX3, O75060, Q5RKT0, Q6IN87, Q6P997, Q86Y03, Q9P1S5	Gene names	RIPK5, KIAA0472, RIP5
Domain Architecture	No domain graphic available
Description	Receptor-interacting serine/threonine-protein kinase 5 (EC 2.7.11.1) (Dusty protein kinase) (Dusty PK) (RIP-homologous kinase).

ST17A_HUMAN
NC score	0.052066 (rank : 815)	θ value	θ > 10 (rank : 802)
Query Neighborhood Hits	207	Target Neighborhood Hits	843	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UEE5, Q8IVC8	Gene names	STK17A, DRAK1
Domain Architecture
Description	Serine/threonine-protein kinase 17A (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 1).

PLK4_HUMAN
NC score	0.051997 (rank : 816)	θ value	θ > 10 (rank : 682)
Query Neighborhood Hits	207	Target Neighborhood Hits	884	Shared Neighborhood Hits	52
SwissProt Accessions	O00444, Q8IYF0, Q96Q95	Gene names	PLK4, SAK, STK18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

PLK4_MOUSE
NC score	0.051986 (rank : 817)	θ value	θ > 10 (rank : 683)
Query Neighborhood Hits	207	Target Neighborhood Hits	879	Shared Neighborhood Hits	50
SwissProt Accessions	Q64702, Q6PEP6, Q78EG6, Q8R0I5, Q9CVR6, Q9CVU6	Gene names	Plk4, Sak, Stk18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

IKKE_MOUSE
NC score	0.051907 (rank : 818)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	207	Target Neighborhood Hits	848	Shared Neighborhood Hits	47
SwissProt Accessions	Q9R0T8	Gene names	Ikbke, Ikke, Ikki
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).

ULK2_MOUSE
NC score	0.051825 (rank : 819)	θ value	θ > 10 (rank : 856)
Query Neighborhood Hits	207	Target Neighborhood Hits	943	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QY01, Q80TV7, Q9WTP4	Gene names	Ulk2, Kiaa0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2) (Serine/threonine-protein kinase Unc51.2).

LRP1B_HUMAN
NC score	0.051824 (rank : 820)	θ value	θ > 10 (rank : 557)
Query Neighborhood Hits	207	Target Neighborhood Hits	602	Shared Neighborhood Hits	30
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

KCC1A_MOUSE
NC score	0.051778 (rank : 821)	θ value	θ > 10 (rank : 476)
Query Neighborhood Hits	207	Target Neighborhood Hits	845	Shared Neighborhood Hits	50
SwissProt Accessions	Q91YS8	Gene names	Camk1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

INAR1_HUMAN
NC score	0.051765 (rank : 822)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	207	Target Neighborhood Hits	49	Shared Neighborhood Hits	17
SwissProt Accessions	P17181, Q53GW9, Q53H11, Q8WTZ2	Gene names	IFNAR1, IFNAR
Domain Architecture	No domain graphic available
Description	Interferon-alpha/beta receptor alpha chain precursor (IFN-alpha-REC).

TRI46_MOUSE
NC score	0.051725 (rank : 823)	θ value	2.36792 (rank : 172)
Query Neighborhood Hits	207	Target Neighborhood Hits	287	Shared Neighborhood Hits	30
SwissProt Accessions	Q7TNM2, Q60717, Q6P1I9	Gene names	Trim46, Trific
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

KCC1A_HUMAN
NC score	0.051703 (rank : 824)	θ value	θ > 10 (rank : 475)
Query Neighborhood Hits	207	Target Neighborhood Hits	846	Shared Neighborhood Hits	50
SwissProt Accessions	Q14012	Gene names	CAMK1
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha).

ACVR1_MOUSE
NC score	0.051690 (rank : 825)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	207	Target Neighborhood Hits	768	Shared Neighborhood Hits	48
SwissProt Accessions	P37172, Q3UDH5, Q91VF1	Gene names	Acvr1, Acvrlk2, Tgfb1
Domain Architecture
Description	Activin receptor type-1 precursor (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I) (TSK-7L).

NIM1_HUMAN
NC score	0.051454 (rank : 826)	θ value	θ > 10 (rank : 644)
Query Neighborhood Hits	207	Target Neighborhood Hits	850	Shared Neighborhood Hits	50
SwissProt Accessions	Q8IY84	Gene names	NIM1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase NIM1 (EC 2.7.11.1).

IKKE_HUMAN
NC score	0.051384 (rank : 827)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	207	Target Neighborhood Hits	837	Shared Neighborhood Hits	47
SwissProt Accessions	Q14164	Gene names	IKBKE, IKKE, IKKI, KIAA0151
Domain Architecture
Description	Inhibitor of nuclear factor kappa-B kinase epsilon subunit (EC 2.7.11.10) (I kappa-B kinase epsilon) (IkBKE) (IKK-epsilon) (IKK- E) (Inducible I kappa-B kinase) (IKK-i).

DLK_MOUSE
NC score	0.051252 (rank : 828)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	207	Target Neighborhood Hits	374	Shared Neighborhood Hits	19
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

PAK7_HUMAN
NC score	0.051251 (rank : 829)	θ value	θ > 10 (rank : 664)
Query Neighborhood Hits	207	Target Neighborhood Hits	875	Shared Neighborhood Hits	50
SwissProt Accessions	Q9P286, Q5W115, Q9BX09, Q9ULF6	Gene names	PAK7, KIAA1264, PAK5
Domain Architecture
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (PAK-5).

LRRK2_MOUSE
NC score	0.051247 (rank : 830)	θ value	θ > 10 (rank : 564)
Query Neighborhood Hits	207	Target Neighborhood Hits	1359	Shared Neighborhood Hits	54
SwissProt Accessions	Q5S006, Q8BWG7, Q8BZJ6, Q8CI84, Q8K062	Gene names	Lrrk2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1).

BMR1B_MOUSE
NC score	0.051189 (rank : 831)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	207	Target Neighborhood Hits	758	Shared Neighborhood Hits	46
SwissProt Accessions	P36898, Q3TRF2	Gene names	Bmpr1b, Acvrlk6
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (Serine/threonine-protein kinase receptor R6) (SKR6) (Activin receptor-like kinase 6) (ALK-6).

NUAK1_HUMAN
NC score	0.051150 (rank : 832)	θ value	θ > 10 (rank : 656)
Query Neighborhood Hits	207	Target Neighborhood Hits	874	Shared Neighborhood Hits	50
SwissProt Accessions	O60285, Q96KA8	Gene names	NUAK1, ARK5, KIAA0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5).

PAK7_MOUSE
NC score	0.051134 (rank : 833)	θ value	θ > 10 (rank : 665)
Query Neighborhood Hits	207	Target Neighborhood Hits	875	Shared Neighborhood Hits	50
SwissProt Accessions	Q8C015, Q3TQJ7, Q6RWS7	Gene names	Pak7, Pak5
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PAK 7 (EC 2.7.11.1) (p21-activated kinase 7) (PAK-7) (p21-activated kinase 5).

ACVR1_HUMAN
NC score	0.051037 (rank : 834)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	207	Target Neighborhood Hits	760	Shared Neighborhood Hits	49
SwissProt Accessions	Q04771	Gene names	ACVR1, ACVRLK2
Domain Architecture
Description	Activin receptor type-1 precursor (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Serine/threonine-protein kinase receptor R1) (SKR1) (Activin receptor-like kinase 2) (ALK-2) (TGF-B superfamily receptor type I) (TSR-I).

NTNG2_MOUSE
NC score	0.050929 (rank : 835)	θ value	θ > 10 (rank : 649)
Query Neighborhood Hits	207	Target Neighborhood Hits	276	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

STK36_HUMAN
NC score	0.050856 (rank : 836)	θ value	θ > 10 (rank : 816)
Query Neighborhood Hits	207	Target Neighborhood Hits	896	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NRP7, Q8TC32, Q9H9N9, Q9UF35, Q9ULE2	Gene names	STK36, KIAA1278
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog).

NUAK2_HUMAN
NC score	0.050840 (rank : 837)	θ value	θ > 10 (rank : 658)
Query Neighborhood Hits	207	Target Neighborhood Hits	874	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H093	Gene names	NUAK2
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (SNF1/AMP kinase-related kinase) (SNARK).

BMR1B_HUMAN
NC score	0.050836 (rank : 838)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	207	Target Neighborhood Hits	760	Shared Neighborhood Hits	46
SwissProt Accessions	O00238, P78366	Gene names	BMPR1B
Domain Architecture
Description	Bone morphogenetic protein receptor type IB precursor (EC 2.7.11.30) (CDw293 antigen).

ANKK1_MOUSE
NC score	0.050780 (rank : 839)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	207	Target Neighborhood Hits	1072	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BZ25	Gene names	Ankk1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and protein kinase domain-containing protein 1 (EC 2.7.11.1).

TRI46_HUMAN
NC score	0.050771 (rank : 840)	θ value	2.36792 (rank : 171)
Query Neighborhood Hits	207	Target Neighborhood Hits	291	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z4K8, Q6NT17, Q6NT41, Q6ZRL7, Q9H5P2	Gene names	TRIM46, TRIFIC
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 46 (Tripartite, fibronectin type- III and C-terminal SPRY motif protein).

ULK3_MOUSE
NC score	0.050738 (rank : 841)	θ value	θ > 10 (rank : 858)
Query Neighborhood Hits	207	Target Neighborhood Hits	872	Shared Neighborhood Hits	50
SwissProt Accessions	Q3U3Q1, Q8K1X6, Q9DBR8	Gene names	Ulk3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3).

DLL4_HUMAN
NC score	0.050694 (rank : 842)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	207	Target Neighborhood Hits	435	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

NUAK1_MOUSE
NC score	0.050628 (rank : 843)	θ value	θ > 10 (rank : 657)
Query Neighborhood Hits	207	Target Neighborhood Hits	881	Shared Neighborhood Hits	50
SwissProt Accessions	Q641K5, Q6I6D6, Q8CGE1	Gene names	Nuak1, Kiaa0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1).

AURKC_HUMAN
NC score	0.050618 (rank : 844)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	207	Target Neighborhood Hits	847	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UQB9, O60681, O75442, Q9UPK5	Gene names	AURKC, AIE2, AIK3, STK13
Domain Architecture
Description	Serine/threonine-protein kinase 13 (EC 2.7.11.1) (Aurora/Ipl1/Eg2 protein 2) (Aurora/Ipl1-related kinase 3) (Aurora-C).

LAMC1_HUMAN
NC score	0.050581 (rank : 845)	θ value	θ > 10 (rank : 524)
Query Neighborhood Hits	207	Target Neighborhood Hits	922	Shared Neighborhood Hits	33
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

SN1L1_MOUSE
NC score	0.050549 (rank : 846)	θ value	θ > 10 (rank : 790)
Query Neighborhood Hits	207	Target Neighborhood Hits	895	Shared Neighborhood Hits	50
SwissProt Accessions	Q60670	Gene names	Snf1lk, Msk
Domain Architecture
Description	Serine/threonine-protein kinase SNF1-like kinase 1 (EC 2.7.11.1) (Serine/threonine-protein kinase SNF1LK) (HRT-20) (Myocardial SNF1- like kinase).

KS6A2_MOUSE
NC score	0.050492 (rank : 847)	θ value	θ > 10 (rank : 501)
Query Neighborhood Hits	207	Target Neighborhood Hits	858	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WUT3, Q9D2C0	Gene names	Rps6ka2, Rsk3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase- activated protein kinase 1c) (MAPKAPK1C).

SN1L2_HUMAN
NC score	0.050447 (rank : 848)	θ value	θ > 10 (rank : 791)
Query Neighborhood Hits	207	Target Neighborhood Hits	964	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H0K1, O94878, Q6AZE2, Q76N03, Q8NCV7, Q96CZ8	Gene names	SNF1LK2, KIAA0781, QIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Qin- induced kinase).

KPSH2_HUMAN
NC score	0.050338 (rank : 849)	θ value	θ > 10 (rank : 485)
Query Neighborhood Hits	207	Target Neighborhood Hits	822	Shared Neighborhood Hits	50
SwissProt Accessions	Q96QS6	Gene names	PSKH2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase H2 (EC 2.7.11.1) (PSK-H2).

NEK9_HUMAN
NC score	0.050321 (rank : 850)	θ value	θ > 10 (rank : 641)
Query Neighborhood Hits	207	Target Neighborhood Hits	900	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TD19, Q52LK6, Q8NCN0, Q8TCY4, Q9UPI4, Q9Y6S4, Q9Y6S5, Q9Y6S6	Gene names	NEK9, KIAA1995, NEK8, NERCC
Domain Architecture
Description	Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (NimA-related protein kinase 9) (Never in mitosis A-related kinase 9) (Nercc1 kinase) (NIMA-related kinase 8) (Nek8).

KS6A3_HUMAN
NC score	0.050303 (rank : 851)	θ value	θ > 10 (rank : 502)
Query Neighborhood Hits	207	Target Neighborhood Hits	859	Shared Neighborhood Hits	50
SwissProt Accessions	P51812, Q4VAP3, Q59H26, Q5JPK8, Q7Z3Z7	Gene names	RPS6KA3, ISPK1, RSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

KS6A2_HUMAN
NC score	0.050290 (rank : 852)	θ value	θ > 10 (rank : 500)
Query Neighborhood Hits	207	Target Neighborhood Hits	857	Shared Neighborhood Hits	50
SwissProt Accessions	Q15349, Q15419, Q59GJ3, Q5TI68, Q96J38, Q9UJN5	Gene names	RPS6KA2, RSK3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C).

KS6A3_MOUSE
NC score	0.050276 (rank : 853)	θ value	θ > 10 (rank : 503)
Query Neighborhood Hits	207	Target Neighborhood Hits	860	Shared Neighborhood Hits	50
SwissProt Accessions	P18654, Q03140, Q8K3J8	Gene names	Rps6ka3, Rps6ka-rs1, Rsk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

WEE1B_MOUSE
NC score	0.050254 (rank : 854)	θ value	θ > 10 (rank : 881)
Query Neighborhood Hits	207	Target Neighborhood Hits	765	Shared Neighborhood Hits	43
SwissProt Accessions	Q66JT0, Q4U4S4, Q7TPV9	Gene names	Wee1b, Wee2
Domain Architecture	No domain graphic available
Description	Wee1-like protein kinase 1B (EC 2.7.10.2) (Wee1B kinase) (mWee1B).

TRI36_MOUSE
NC score	0.050161 (rank : 855)	θ value	θ > 10 (rank : 847)
Query Neighborhood Hits	207	Target Neighborhood Hits	266	Shared Neighborhood Hits	33
SwissProt Accessions	Q80WG7, Q7TNM1	Gene names	Trim36
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Haprin) (Acrosome RBCC protein).

ULK3_HUMAN
NC score	0.050139 (rank : 856)	θ value	θ > 10 (rank : 857)
Query Neighborhood Hits	207	Target Neighborhood Hits	830	Shared Neighborhood Hits	50
SwissProt Accessions	Q6PHR2, Q9NPN5, Q9UFS4	Gene names	ULK3
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK3 (EC 2.7.11.1) (Unc-51-like kinase 3).

KRA44_HUMAN
NC score	0.050073 (rank : 857)	θ value	θ > 10 (rank : 490)
Query Neighborhood Hits	207	Target Neighborhood Hits	162	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

SN1L2_MOUSE
NC score	0.050065 (rank : 858)	θ value	θ > 10 (rank : 792)
Query Neighborhood Hits	207	Target Neighborhood Hits	944	Shared Neighborhood Hits	51
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).

LAMC2_MOUSE
NC score	0.050024 (rank : 859)	θ value	θ > 10 (rank : 526)
Query Neighborhood Hits	207	Target Neighborhood Hits	614	Shared Neighborhood Hits	39
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

STK39_MOUSE
NC score	0.050020 (rank : 860)	θ value	θ > 10 (rank : 818)
Query Neighborhood Hits	207	Target Neighborhood Hits	915	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

K0195_HUMAN
NC score	0.043783 (rank : 861)	θ value	0.62314 (rank : 161)
Query Neighborhood Hits	207	Target Neighborhood Hits	61	Shared Neighborhood Hits	7
SwissProt Accessions	Q12767, O75536, Q86XF1	Gene names	KIAA0195, TMEM94
Domain Architecture	No domain graphic available
Description	Protein KIAA0195 (Transmembrane protein 94).

K0195_MOUSE
NC score	0.040737 (rank : 862)	θ value	0.62314 (rank : 162)
Query Neighborhood Hits	207	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q7TSH8, Q80U66, Q8BL05, Q8K0Q0, Q91VY1	Gene names	Kiaa0195
Domain Architecture	No domain graphic available
Description	Protein KIAA0195.

COIA1_MOUSE
NC score	0.038432 (rank : 863)	θ value	3.0926 (rank : 173)
Query Neighborhood Hits	207	Target Neighborhood Hits	481	Shared Neighborhood Hits	12
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

XYLB_MOUSE
NC score	0.034726 (rank : 864)	θ value	1.06291 (rank : 167)
Query Neighborhood Hits	207	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q3TNA1, Q8R156	Gene names	Xylb
Domain Architecture	No domain graphic available
Description	Xylulose kinase (EC 2.7.1.17) (Xylulokinase).

I10R2_MOUSE
NC score	0.032700 (rank : 865)	θ value	8.99809 (rank : 200)
Query Neighborhood Hits	207	Target Neighborhood Hits	52	Shared Neighborhood Hits	13
SwissProt Accessions	Q61190	Gene names	Il10rb, Crfb4
Domain Architecture
Description	Interleukin-10 receptor beta chain precursor (IL-10R-B) (IL-10R2) (Cytokine receptor family 2 member 4) (Cytokine receptor class-II member 4) (CRF2-4) (CDw210b antigen).

COFA1_HUMAN
NC score	0.031047 (rank : 866)	θ value	6.88961 (rank : 192)
Query Neighborhood Hits	207	Target Neighborhood Hits	292	Shared Neighborhood Hits	19
SwissProt Accessions	P39059, Q5T6J4, Q9Y4W4	Gene names	COL15A1
Domain Architecture
Description	Collagen alpha-1(XV) chain precursor [Contains: Endostatin (Endostatin-XV) (Restin) (Related to endostatin)].

TR19L_MOUSE
NC score	0.023807 (rank : 867)	θ value	6.88961 (rank : 196)
Query Neighborhood Hits	207	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BX43, Q8BTV0	Gene names	Tnfrsf19l
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 19L precursor.

TR19L_HUMAN
NC score	0.023544 (rank : 868)	θ value	4.03905 (rank : 184)
Query Neighborhood Hits	207	Target Neighborhood Hits	99	Shared Neighborhood Hits	13
SwissProt Accessions	Q969Z4, Q86V34, Q96JU1, Q9BUX7	Gene names	TNFRSF19L, RELT
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 19L precursor (Receptor expressed in lymphoid tissues).

FLRT3_HUMAN
NC score	0.021268 (rank : 869)	θ value	1.06291 (rank : 166)
Query Neighborhood Hits	207	Target Neighborhood Hits	281	Shared Neighborhood Hits	23
SwissProt Accessions	Q9NZU0, Q96K39, Q96K42, Q96KB1, Q9P259	Gene names	FLRT3, KIAA1469
Domain Architecture
Description	Leucine-rich repeat transmembrane protein FLRT3 precursor (Fibronectin-like domain-containing leucine-rich transmembrane protein 3).

K0586_HUMAN
NC score	0.018840 (rank : 870)	θ value	3.0926 (rank : 175)
Query Neighborhood Hits	207	Target Neighborhood Hits	311	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BVV6, O60328	Gene names	KIAA0586
Domain Architecture	No domain graphic available
Description	Protein KIAA0586.

I13R1_HUMAN
NC score	0.017495 (rank : 871)	θ value	8.99809 (rank : 202)
Query Neighborhood Hits	207	Target Neighborhood Hits	31	Shared Neighborhood Hits	8
SwissProt Accessions	P78552, O95646, Q99656	Gene names	IL13RA1, IL13R, IL13RA
Domain Architecture	No domain graphic available
Description	Interleukin-13 receptor alpha-1 chain precursor (IL-13R-alpha-1) (IL- 13RA-1) (CD213a1 antigen).

NFRKB_HUMAN
NC score	0.016020 (rank : 872)	θ value	4.03905 (rank : 181)
Query Neighborhood Hits	207	Target Neighborhood Hits	211	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NBR1_HUMAN
NC score	0.014469 (rank : 873)	θ value	4.03905 (rank : 180)
Query Neighborhood Hits	207	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	Q14596, Q13173, Q15026, Q96GB6, Q9NRF7	Gene names	NBR1, 1A13B, KIAA0049, M17S2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2) (1A1-3B).

TSH3_HUMAN
NC score	0.011188 (rank : 874)	θ value	1.38821 (rank : 169)
Query Neighborhood Hits	207	Target Neighborhood Hits	564	Shared Neighborhood Hits	6
SwissProt Accessions	Q63HK5, Q9H0G6, Q9P254	Gene names	TSHZ3, KIAA1474, TSH3, ZNF537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

NBR1_MOUSE
NC score	0.010997 (rank : 875)	θ value	8.99809 (rank : 204)
Query Neighborhood Hits	207	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	P97432, Q9JIH9	Gene names	Nbr1, M17s2
Domain Architecture
Description	Next to BRCA1 gene 1 protein (Neighbor of BRCA1 gene 1 protein) (Membrane component, chromosome 17, surface marker 2).

BCDO2_MOUSE
NC score	0.010438 (rank : 876)	θ value	8.99809 (rank : 197)
Query Neighborhood Hits	207	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q99NF1	Gene names	Bcdo2
Domain Architecture
Description	Beta,beta-carotene 9',10'-dioxygenase (EC 1.14.99.-) (Beta-carotene dioxygenase 2) (B-diox-II).

TSH3_MOUSE
NC score	0.009593 (rank : 877)	θ value	3.0926 (rank : 176)
Query Neighborhood Hits	207	Target Neighborhood Hits	590	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

LBR_HUMAN
NC score	0.009045 (rank : 878)	θ value	4.03905 (rank : 179)
Query Neighborhood Hits	207	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q14739, Q14740, Q53GU7, Q59FE6	Gene names	LBR
Domain Architecture
Description	Lamin-B receptor (Integral nuclear envelope inner membrane protein) (LMN2R).

MCM3A_HUMAN
NC score	0.008572 (rank : 879)	θ value	6.88961 (rank : 195)
Query Neighborhood Hits	207	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	O60318, Q9UMT4	Gene names	MCM3AP, GANP, KIAA0572, MAP80
Domain Architecture
Description	80 kDa MCM3-associated protein (GANP protein).

DAB2_MOUSE
NC score	0.007334 (rank : 880)	θ value	5.27518 (rank : 188)
Query Neighborhood Hits	207	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	P98078, Q3U3K1, Q91W56, Q923E1	Gene names	Dab2, Doc2
Domain Architecture
Description	Disabled homolog 2 (DOC-2) (Mitogen-responsive phosphoprotein).

RFX2_HUMAN
NC score	0.006897 (rank : 881)	θ value	4.03905 (rank : 182)
Query Neighborhood Hits	207	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P48378	Gene names	RFX2
Domain Architecture
Description	DNA-binding protein RFX2.

TREF1_HUMAN
NC score	0.006630 (rank : 882)	θ value	5.27518 (rank : 190)
Query Neighborhood Hits	207	Target Neighborhood Hits	651	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

MYCD_MOUSE
NC score	0.003953 (rank : 883)	θ value	8.99809 (rank : 203)
Query Neighborhood Hits	207	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VIM5, Q8C3W6, Q8VIL4	Gene names	Myocd, Bsac2, Mycd, Srfcp
Domain Architecture
Description	Myocardin (SRF cofactor protein) (Basic SAP coiled-coil transcription activator 2).

AL3A1_HUMAN
NC score	0.003354 (rank : 884)	θ value	5.27518 (rank : 185)
Query Neighborhood Hits	207	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	P30838, Q9BT37	Gene names	ALDH3A1, ALDH3
Domain Architecture
Description	Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (ALDH class 3) (ALDHIII).

ABI2_MOUSE
NC score	0.002227 (rank : 885)	θ value	6.88961 (rank : 191)
Query Neighborhood Hits	207	Target Neighborhood Hits	266	Shared Neighborhood Hits	3
SwissProt Accessions	P62484, Q6PHU3	Gene names	Abi2
Domain Architecture	No domain graphic available
Description	Abl interactor 2 (Abelson interactor 2) (Abi-2).

SMCA5_MOUSE
NC score	0.002175 (rank : 886)	θ value	4.03905 (rank : 183)
Query Neighborhood Hits	207	Target Neighborhood Hits	80	Shared Neighborhood Hits	2
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

FOXC1_MOUSE
NC score	-0.000717 (rank : 887)	θ value	6.88961 (rank : 193)
Query Neighborhood Hits	207	Target Neighborhood Hits	218	Shared Neighborhood Hits	3
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

CDX1_MOUSE
NC score	-0.001769 (rank : 888)	θ value	5.27518 (rank : 186)
Query Neighborhood Hits	207	Target Neighborhood Hits	379	Shared Neighborhood Hits	4
SwissProt Accessions	P18111, Q8VCF7	Gene names	Cdx1, Cdx-1
Domain Architecture
Description	Homeobox protein CDX-1 (Caudal-type homeobox protein 1).