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Network neighborhood for query Sequence : LCE3C_HUMAN

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LCE3C_HUMAN
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

LCE3C_HUMAN
θ value	5.26297e-08 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

LCE3B_HUMAN
θ value	0.0193708 (rank : 2)	NC score	0.610013 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

TIE1_HUMAN
θ value	0.125558 (rank : 3)	NC score	0.085029 (rank : 37)
Query Neighborhood Hits	15	Target Neighborhood Hits	1241	Shared Neighborhood Hits	9
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

TIE1_MOUSE
θ value	0.125558 (rank : 4)	NC score	0.086232 (rank : 34)
Query Neighborhood Hits	15	Target Neighborhood Hits	1266	Shared Neighborhood Hits	12
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

LCE3E_HUMAN
θ value	0.279714 (rank : 5)	NC score	0.571487 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q5T5B0	Gene names	LCE3E, LEP17
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3E (Late envelope protein 17).

LCE3A_HUMAN
θ value	0.365318 (rank : 6)	NC score	0.592667 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

GRN_HUMAN
θ value	0.813845 (rank : 7)	NC score	0.161742 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	268	Shared Neighborhood Hits	11
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

LCE3D_HUMAN
θ value	1.06291 (rank : 8)	NC score	0.450230 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYE3	Gene names	LCE3D, LEP16, SPRL6A, SPRL6B
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3D (Late envelope protein 16) (Small proline-rich-like epidermal differentiation complex protein 6A) (Small proline-rich-like epidermal differentiation complex protein 6B).

NOTC2_HUMAN
θ value	1.38821 (rank : 9)	NC score	0.076492 (rank : 50)
Query Neighborhood Hits	15	Target Neighborhood Hits	1113	Shared Neighborhood Hits	11
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ZAN_MOUSE
θ value	1.38821 (rank : 10)	NC score	0.125847 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	808	Shared Neighborhood Hits	13
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

SREC_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.113929 (rank : 16)
Query Neighborhood Hits	15	Target Neighborhood Hits	645	Shared Neighborhood Hits	12
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

STAB1_HUMAN
θ value	4.03905 (rank : 12)	NC score	0.089261 (rank : 28)
Query Neighborhood Hits	15	Target Neighborhood Hits	546	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

ADA32_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.028303 (rank : 147)
Query Neighborhood Hits	15	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).

NOTC4_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.077561 (rank : 47)
Query Neighborhood Hits	15	Target Neighborhood Hits	905	Shared Neighborhood Hits	12
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

ZAN_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.106902 (rank : 17)
Query Neighborhood Hits	15	Target Neighborhood Hits	679	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

AGRIN_HUMAN
θ value	θ > 10 (rank : 16)	NC score	0.066509 (rank : 81)
Query Neighborhood Hits	15	Target Neighborhood Hits	582	Shared Neighborhood Hits	11
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

BMPER_HUMAN
θ value	θ > 10 (rank : 17)	NC score	0.060284 (rank : 106)
Query Neighborhood Hits	15	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
θ value	θ > 10 (rank : 18)	NC score	0.053221 (rank : 133)
Query Neighborhood Hits	15	Target Neighborhood Hits	194	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

CFC1_HUMAN
θ value	θ > 10 (rank : 19)	NC score	0.062997 (rank : 94)
Query Neighborhood Hits	15	Target Neighborhood Hits	148	Shared Neighborhood Hits	6
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CRUM1_HUMAN
θ value	θ > 10 (rank : 20)	NC score	0.061489 (rank : 102)
Query Neighborhood Hits	15	Target Neighborhood Hits	457	Shared Neighborhood Hits	9
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 21)	NC score	0.062382 (rank : 97)
Query Neighborhood Hits	15	Target Neighborhood Hits	444	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
θ value	θ > 10 (rank : 22)	NC score	0.067598 (rank : 78)
Query Neighborhood Hits	15	Target Neighborhood Hits	453	Shared Neighborhood Hits	9
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CUBN_HUMAN
θ value	θ > 10 (rank : 23)	NC score	0.050808 (rank : 142)
Query Neighborhood Hits	15	Target Neighborhood Hits	482	Shared Neighborhood Hits	10
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 24)	NC score	0.050382 (rank : 145)
Query Neighborhood Hits	15	Target Neighborhood Hits	477	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

DLK_HUMAN
θ value	θ > 10 (rank : 25)	NC score	0.074542 (rank : 54)
Query Neighborhood Hits	15	Target Neighborhood Hits	401	Shared Neighborhood Hits	10
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	θ > 10 (rank : 26)	NC score	0.074202 (rank : 55)
Query Neighborhood Hits	15	Target Neighborhood Hits	374	Shared Neighborhood Hits	11
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL1_HUMAN
θ value	θ > 10 (rank : 27)	NC score	0.066490 (rank : 82)
Query Neighborhood Hits	15	Target Neighborhood Hits	455	Shared Neighborhood Hits	10
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
θ value	θ > 10 (rank : 28)	NC score	0.067567 (rank : 79)
Query Neighborhood Hits	15	Target Neighborhood Hits	456	Shared Neighborhood Hits	10
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL3_HUMAN
θ value	θ > 10 (rank : 29)	NC score	0.065304 (rank : 87)
Query Neighborhood Hits	15	Target Neighborhood Hits	419	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	θ > 10 (rank : 30)	NC score	0.069720 (rank : 72)
Query Neighborhood Hits	15	Target Neighborhood Hits	399	Shared Neighborhood Hits	9
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL4_HUMAN
θ value	θ > 10 (rank : 31)	NC score	0.071855 (rank : 67)
Query Neighborhood Hits	15	Target Neighborhood Hits	435	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
θ value	θ > 10 (rank : 32)	NC score	0.071985 (rank : 65)
Query Neighborhood Hits	15	Target Neighborhood Hits	440	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.067727 (rank : 75)
Query Neighborhood Hits	15	Target Neighborhood Hits	460	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 34)	NC score	0.066620 (rank : 80)
Query Neighborhood Hits	15	Target Neighborhood Hits	413	Shared Neighborhood Hits	9
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

EDIL3_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.054518 (rank : 127)
Query Neighborhood Hits	15	Target Neighborhood Hits	292	Shared Neighborhood Hits	8
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.055281 (rank : 124)
Query Neighborhood Hits	15	Target Neighborhood Hits	317	Shared Neighborhood Hits	8
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EGFL7_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.053008 (rank : 135)
Query Neighborhood Hits	15	Target Neighborhood Hits	325	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.051688 (rank : 138)
Query Neighborhood Hits	15	Target Neighborhood Hits	287	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL9_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.073377 (rank : 57)
Query Neighborhood Hits	15	Target Neighborhood Hits	365	Shared Neighborhood Hits	9
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 40)	NC score	0.072925 (rank : 62)
Query Neighborhood Hits	15	Target Neighborhood Hits	379	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

ESM1_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.084968 (rank : 38)
Query Neighborhood Hits	15	Target Neighborhood Hits	110	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

ESM1_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.051060 (rank : 140)
Query Neighborhood Hits	15	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

FBN1_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.058692 (rank : 111)
Query Neighborhood Hits	15	Target Neighborhood Hits	557	Shared Neighborhood Hits	10
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.058268 (rank : 113)
Query Neighborhood Hits	15	Target Neighborhood Hits	563	Shared Neighborhood Hits	10
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.058667 (rank : 112)
Query Neighborhood Hits	15	Target Neighborhood Hits	560	Shared Neighborhood Hits	10
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 46)	NC score	0.056985 (rank : 119)
Query Neighborhood Hits	15	Target Neighborhood Hits	549	Shared Neighborhood Hits	10
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.061634 (rank : 100)
Query Neighborhood Hits	15	Target Neighborhood Hits	543	Shared Neighborhood Hits	11
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

GRN_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.135783 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	248	Shared Neighborhood Hits	9
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HHIP_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.061381 (rank : 103)
Query Neighborhood Hits	15	Target Neighborhood Hits	249	Shared Neighborhood Hits	8
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	θ > 10 (rank : 50)	NC score	0.057483 (rank : 117)
Query Neighborhood Hits	15	Target Neighborhood Hits	219	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ITB4_HUMAN
θ value	θ > 10 (rank : 51)	NC score	0.053354 (rank : 132)
Query Neighborhood Hits	15	Target Neighborhood Hits	458	Shared Neighborhood Hits	8
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

JAG1_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.071099 (rank : 69)
Query Neighborhood Hits	15	Target Neighborhood Hits	514	Shared Neighborhood Hits	9
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.070368 (rank : 70)
Query Neighborhood Hits	15	Target Neighborhood Hits	518	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.073302 (rank : 59)
Query Neighborhood Hits	15	Target Neighborhood Hits	491	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.073121 (rank : 61)
Query Neighborhood Hits	15	Target Neighborhood Hits	504	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

KR101_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.079607 (rank : 45)
Query Neighborhood Hits	15	Target Neighborhood Hits	261	Shared Neighborhood Hits	10
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.076249 (rank : 52)
Query Neighborhood Hits	15	Target Neighborhood Hits	264	Shared Neighborhood Hits	9
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR104_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.076961 (rank : 48)
Query Neighborhood Hits	15	Target Neighborhood Hits	313	Shared Neighborhood Hits	8
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.066281 (rank : 83)
Query Neighborhood Hits	15	Target Neighborhood Hits	271	Shared Neighborhood Hits	9
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR106_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.067599 (rank : 77)
Query Neighborhood Hits	15	Target Neighborhood Hits	347	Shared Neighborhood Hits	8
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.076335 (rank : 51)
Query Neighborhood Hits	15	Target Neighborhood Hits	330	Shared Neighborhood Hits	9
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR108_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.064340 (rank : 91)
Query Neighborhood Hits	15	Target Neighborhood Hits	226	Shared Neighborhood Hits	8
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.069824 (rank : 71)
Query Neighborhood Hits	15	Target Neighborhood Hits	226	Shared Neighborhood Hits	7
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10B_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.064482 (rank : 90)
Query Neighborhood Hits	15	Target Neighborhood Hits	269	Shared Neighborhood Hits	7
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.059951 (rank : 109)
Query Neighborhood Hits	15	Target Neighborhood Hits	219	Shared Neighborhood Hits	8
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR171_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.090914 (rank : 25)
Query Neighborhood Hits	15	Target Neighborhood Hits	144	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR412_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.060276 (rank : 107)
Query Neighborhood Hits	15	Target Neighborhood Hits	178	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR414_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.053890 (rank : 131)
Query Neighborhood Hits	15	Target Neighborhood Hits	199	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR510_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.065765 (rank : 84)
Query Neighborhood Hits	15	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR511_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.101469 (rank : 19)
Query Neighborhood Hits	15	Target Neighborhood Hits	231	Shared Neighborhood Hits	10
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA11_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.071958 (rank : 66)
Query Neighborhood Hits	15	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA13_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.065612 (rank : 85)
Query Neighborhood Hits	15	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA15_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.064195 (rank : 92)
Query Neighborhood Hits	15	Target Neighborhood Hits	126	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA44_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.054898 (rank : 126)
Query Neighborhood Hits	15	Target Neighborhood Hits	162	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA45_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.061582 (rank : 101)
Query Neighborhood Hits	15	Target Neighborhood Hits	194	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA47_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.055024 (rank : 125)
Query Neighborhood Hits	15	Target Neighborhood Hits	204	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA51_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.090816 (rank : 26)
Query Neighborhood Hits	15	Target Neighborhood Hits	288	Shared Neighborhood Hits	10
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.082563 (rank : 43)
Query Neighborhood Hits	15	Target Neighborhood Hits	236	Shared Neighborhood Hits	9
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA53_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.095869 (rank : 23)
Query Neighborhood Hits	15	Target Neighborhood Hits	331	Shared Neighborhood Hits	10
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.085515 (rank : 36)
Query Neighborhood Hits	15	Target Neighborhood Hits	270	Shared Neighborhood Hits	10
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.087747 (rank : 31)
Query Neighborhood Hits	15	Target Neighborhood Hits	257	Shared Neighborhood Hits	10
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA56_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.096483 (rank : 22)
Query Neighborhood Hits	15	Target Neighborhood Hits	207	Shared Neighborhood Hits	10
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.083924 (rank : 40)
Query Neighborhood Hits	15	Target Neighborhood Hits	269	Shared Neighborhood Hits	10
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.099354 (rank : 21)
Query Neighborhood Hits	15	Target Neighborhood Hits	324	Shared Neighborhood Hits	10
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.088427 (rank : 30)
Query Neighborhood Hits	15	Target Neighborhood Hits	310	Shared Neighborhood Hits	10
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA92_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.068811 (rank : 74)
Query Neighborhood Hits	15	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.056243 (rank : 122)
Query Neighborhood Hits	15	Target Neighborhood Hits	203	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.065309 (rank : 86)
Query Neighborhood Hits	15	Target Neighborhood Hits	204	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.079277 (rank : 46)
Query Neighborhood Hits	15	Target Neighborhood Hits	185	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.071335 (rank : 68)
Query Neighborhood Hits	15	Target Neighborhood Hits	173	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

LAMA5_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.065298 (rank : 88)
Query Neighborhood Hits	15	Target Neighborhood Hits	976	Shared Neighborhood Hits	13
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.059035 (rank : 110)
Query Neighborhood Hits	15	Target Neighborhood Hits	828	Shared Neighborhood Hits	9
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB2_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.054197 (rank : 129)
Query Neighborhood Hits	15	Target Neighborhood Hits	692	Shared Neighborhood Hits	8
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.050281 (rank : 146)
Query Neighborhood Hits	15	Target Neighborhood Hits	722	Shared Neighborhood Hits	8
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LCE1A_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.281931 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1B_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.214361 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	58	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.198757 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	65	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1D_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.159320 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.216427 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1F_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.241618 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE2A_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.086203 (rank : 35)
Query Neighborhood Hits	15	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LCE4A_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.151628 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

LCE5A_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.072894 (rank : 63)
Query Neighborhood Hits	15	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

LTBP2_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.051032 (rank : 141)
Query Neighborhood Hits	15	Target Neighborhood Hits	552	Shared Neighborhood Hits	10
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP2_MOUSE
θ value	θ > 10 (rank : 105)	NC score	0.050757 (rank : 144)
Query Neighborhood Hits	15	Target Neighborhood Hits	617	Shared Neighborhood Hits	9
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.053218 (rank : 134)
Query Neighborhood Hits	15	Target Neighborhood Hits	502	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.060395 (rank : 105)
Query Neighborhood Hits	15	Target Neighborhood Hits	607	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MCSP_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.088541 (rank : 29)
Query Neighborhood Hits	15	Target Neighborhood Hits	108	Shared Neighborhood Hits	8
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

MEGF6_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.094013 (rank : 24)
Query Neighborhood Hits	15	Target Neighborhood Hits	671	Shared Neighborhood Hits	12
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MEGF8_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.056493 (rank : 121)
Query Neighborhood Hits	15	Target Neighborhood Hits	528	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.057244 (rank : 118)
Query Neighborhood Hits	15	Target Neighborhood Hits	520	Shared Neighborhood Hits	10
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.052196 (rank : 137)
Query Neighborhood Hits	15	Target Neighborhood Hits	557	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.053896 (rank : 130)
Query Neighborhood Hits	15	Target Neighborhood Hits	896	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MUC5B_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.060933 (rank : 104)
Query Neighborhood Hits	15	Target Neighborhood Hits	1020	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NAGPA_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.087337 (rank : 32)
Query Neighborhood Hits	15	Target Neighborhood Hits	282	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NAGPA_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.090337 (rank : 27)
Query Neighborhood Hits	15	Target Neighborhood Hits	308	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NELL1_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.065245 (rank : 89)
Query Neighborhood Hits	15	Target Neighborhood Hits	451	Shared Neighborhood Hits	9
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.062772 (rank : 96)
Query Neighborhood Hits	15	Target Neighborhood Hits	449	Shared Neighborhood Hits	10
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.062375 (rank : 98)
Query Neighborhood Hits	15	Target Neighborhood Hits	436	Shared Neighborhood Hits	11
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NOTC1_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.073369 (rank : 58)
Query Neighborhood Hits	15	Target Neighborhood Hits	906	Shared Neighborhood Hits	10
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC1_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.072389 (rank : 64)
Query Neighborhood Hits	15	Target Neighborhood Hits	916	Shared Neighborhood Hits	10
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.076672 (rank : 49)
Query Neighborhood Hits	15	Target Neighborhood Hits	1069	Shared Neighborhood Hits	10
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC3_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.073801 (rank : 56)
Query Neighborhood Hits	15	Target Neighborhood Hits	1062	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.073270 (rank : 60)
Query Neighborhood Hits	15	Target Neighborhood Hits	975	Shared Neighborhood Hits	10
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.075536 (rank : 53)
Query Neighborhood Hits	15	Target Neighborhood Hits	872	Shared Neighborhood Hits	11
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

PCSK5_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.058046 (rank : 114)
Query Neighborhood Hits	15	Target Neighborhood Hits	613	Shared Neighborhood Hits	9
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

SPR2D_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.051602 (rank : 139)
Query Neighborhood Hits	15	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

SPR2E_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.050771 (rank : 143)
Query Neighborhood Hits	15	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

SPR2F_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.052800 (rank : 136)
Query Neighborhood Hits	15	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

SPR2I_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.056585 (rank : 120)
Query Neighborhood Hits	15	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

SREC2_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.102919 (rank : 18)
Query Neighborhood Hits	15	Target Neighborhood Hits	645	Shared Neighborhood Hits	12
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.100901 (rank : 20)
Query Neighborhood Hits	15	Target Neighborhood Hits	605	Shared Neighborhood Hits	11
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SSPO_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.056022 (rank : 123)
Query Neighborhood Hits	15	Target Neighborhood Hits	800	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

STAB1_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.086845 (rank : 33)
Query Neighborhood Hits	15	Target Neighborhood Hits	566	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.083796 (rank : 41)
Query Neighborhood Hits	15	Target Neighborhood Hits	534	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

STAB2_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.084735 (rank : 39)
Query Neighborhood Hits	15	Target Neighborhood Hits	528	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

TECTA_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.067620 (rank : 76)
Query Neighborhood Hits	15	Target Neighborhood Hits	239	Shared Neighborhood Hits	9
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

TECTA_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.069151 (rank : 73)
Query Neighborhood Hits	15	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TENA_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.060218 (rank : 108)
Query Neighborhood Hits	15	Target Neighborhood Hits	631	Shared Neighborhood Hits	10
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.057566 (rank : 116)
Query Neighborhood Hits	15	Target Neighborhood Hits	596	Shared Neighborhood Hits	10
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENX_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.062358 (rank : 99)
Query Neighborhood Hits	15	Target Neighborhood Hits	789	Shared Neighborhood Hits	10
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TIE2_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.062950 (rank : 95)
Query Neighborhood Hits	15	Target Neighborhood Hits	1192	Shared Neighborhood Hits	8
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

TIE2_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.063321 (rank : 93)
Query Neighborhood Hits	15	Target Neighborhood Hits	1204	Shared Neighborhood Hits	8
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

VWF_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.054298 (rank : 128)
Query Neighborhood Hits	15	Target Neighborhood Hits	396	Shared Neighborhood Hits	9
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

VWF_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.057971 (rank : 115)
Query Neighborhood Hits	15	Target Neighborhood Hits	381	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

WIF1_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.082476 (rank : 44)
Query Neighborhood Hits	15	Target Neighborhood Hits	392	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

WIF1_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.082884 (rank : 42)
Query Neighborhood Hits	15	Target Neighborhood Hits	393	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

Hits sorted by NC score

LCE3C_HUMAN
NC score	0.999962 (rank : 1)	θ value	5.26297e-08 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q5T5A8	Gene names	LCE3C, LEP15, SPRL3A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3C (Late envelope protein 15) (Small proline-rich-like epidermal differentiation complex protein 3A).

LCE3B_HUMAN
NC score	0.610013 (rank : 2)	θ value	0.0193708 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q5TA77	Gene names	LCE3B, LEP14
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3B (Late envelope protein 14).

LCE3A_HUMAN
NC score	0.592667 (rank : 3)	θ value	0.365318 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	29	Shared Neighborhood Hits	11
SwissProt Accessions	Q5TA76	Gene names	LCE3A, LEP13
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3A (Late envelope protein 13).

LCE3E_HUMAN
NC score	0.571487 (rank : 4)	θ value	0.279714 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q5T5B0	Gene names	LCE3E, LEP17
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3E (Late envelope protein 17).

LCE3D_HUMAN
NC score	0.450230 (rank : 5)	θ value	1.06291 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYE3	Gene names	LCE3D, LEP16, SPRL6A, SPRL6B
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 3D (Late envelope protein 16) (Small proline-rich-like epidermal differentiation complex protein 6A) (Small proline-rich-like epidermal differentiation complex protein 6B).

LCE1A_HUMAN
NC score	0.281931 (rank : 6)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	15	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T7P2	Gene names	LCE1A, LEP1
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1A (Late envelope protein 1).

LCE1F_HUMAN
NC score	0.241618 (rank : 7)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	15	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T754	Gene names	LCE1F, LEP6
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1F (Late envelope protein 6).

LCE1E_HUMAN
NC score	0.216427 (rank : 8)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	15	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LCE1B_HUMAN
NC score	0.214361 (rank : 9)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	15	Target Neighborhood Hits	58	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
NC score	0.198757 (rank : 10)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	15	Target Neighborhood Hits	65	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

GRN_HUMAN
NC score	0.161742 (rank : 11)	θ value	0.813845 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	268	Shared Neighborhood Hits	11
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

LCE1D_HUMAN
NC score	0.159320 (rank : 12)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	15	Target Neighborhood Hits	44	Shared Neighborhood Hits	7
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE4A_HUMAN
NC score	0.151628 (rank : 13)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	15	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q5TA78	Gene names	LCE4A, LEP8, SPRL4A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 4A (Late envelope protein 8) (Small proline-rich-like epidermal differentiation complex protein 4A).

GRN_MOUSE
NC score	0.135783 (rank : 14)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	15	Target Neighborhood Hits	248	Shared Neighborhood Hits	9
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

ZAN_MOUSE
NC score	0.125847 (rank : 15)	θ value	1.38821 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	808	Shared Neighborhood Hits	13
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

SREC_HUMAN
NC score	0.113929 (rank : 16)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	645	Shared Neighborhood Hits	12
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

ZAN_HUMAN
NC score	0.106902 (rank : 17)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	679	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

SREC2_HUMAN
NC score	0.102919 (rank : 18)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	15	Target Neighborhood Hits	645	Shared Neighborhood Hits	12
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

KR511_HUMAN
NC score	0.101469 (rank : 19)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	15	Target Neighborhood Hits	231	Shared Neighborhood Hits	10
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

SREC2_MOUSE
NC score	0.100901 (rank : 20)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	15	Target Neighborhood Hits	605	Shared Neighborhood Hits	11
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

KRA58_HUMAN
NC score	0.099354 (rank : 21)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	15	Target Neighborhood Hits	324	Shared Neighborhood Hits	10
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA56_HUMAN
NC score	0.096483 (rank : 22)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	15	Target Neighborhood Hits	207	Shared Neighborhood Hits	10
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA53_HUMAN
NC score	0.095869 (rank : 23)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	15	Target Neighborhood Hits	331	Shared Neighborhood Hits	10
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

MEGF6_HUMAN
NC score	0.094013 (rank : 24)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	15	Target Neighborhood Hits	671	Shared Neighborhood Hits	12
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

KR171_HUMAN
NC score	0.090914 (rank : 25)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	15	Target Neighborhood Hits	144	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KRA51_HUMAN
NC score	0.090816 (rank : 26)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	15	Target Neighborhood Hits	288	Shared Neighborhood Hits	10
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

NAGPA_MOUSE
NC score	0.090337 (rank : 27)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	15	Target Neighborhood Hits	308	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

STAB1_HUMAN
NC score	0.089261 (rank : 28)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	546	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

MCSP_MOUSE
NC score	0.088541 (rank : 29)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	15	Target Neighborhood Hits	108	Shared Neighborhood Hits	8
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

KRA59_HUMAN
NC score	0.088427 (rank : 30)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	15	Target Neighborhood Hits	310	Shared Neighborhood Hits	10
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA55_HUMAN
NC score	0.087747 (rank : 31)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	15	Target Neighborhood Hits	257	Shared Neighborhood Hits	10
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

NAGPA_HUMAN
NC score	0.087337 (rank : 32)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	15	Target Neighborhood Hits	282	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

STAB1_MOUSE
NC score	0.086845 (rank : 33)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	15	Target Neighborhood Hits	566	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

TIE1_MOUSE
NC score	0.086232 (rank : 34)	θ value	0.125558 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	1266	Shared Neighborhood Hits	12
SwissProt Accessions	Q06806, Q811F4	Gene names	Tie1, Tie, Tie-1
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

LCE2A_HUMAN
NC score	0.086203 (rank : 35)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	15	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

KRA54_HUMAN
NC score	0.085515 (rank : 36)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	15	Target Neighborhood Hits	270	Shared Neighborhood Hits	10
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

TIE1_HUMAN
NC score	0.085029 (rank : 37)	θ value	0.125558 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	1241	Shared Neighborhood Hits	9
SwissProt Accessions	P35590	Gene names	TIE1, TIE
Domain Architecture
Description	Tyrosine-protein kinase receptor Tie-1 precursor (EC 2.7.10.1).

ESM1_HUMAN
NC score	0.084968 (rank : 38)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	15	Target Neighborhood Hits	110	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQ30, Q15330, Q96ES3	Gene names	ESM1
Domain Architecture	No domain graphic available
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

STAB2_MOUSE
NC score	0.084735 (rank : 39)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	15	Target Neighborhood Hits	528	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

KRA57_HUMAN
NC score	0.083924 (rank : 40)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	15	Target Neighborhood Hits	269	Shared Neighborhood Hits	10
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

STAB2_HUMAN
NC score	0.083796 (rank : 41)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	15	Target Neighborhood Hits	534	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

WIF1_MOUSE
NC score	0.082884 (rank : 42)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	15	Target Neighborhood Hits	393	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

KRA52_HUMAN
NC score	0.082563 (rank : 43)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	15	Target Neighborhood Hits	236	Shared Neighborhood Hits	9
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

WIF1_HUMAN
NC score	0.082476 (rank : 44)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	15	Target Neighborhood Hits	392	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

KR101_HUMAN
NC score	0.079607 (rank : 45)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	15	Target Neighborhood Hits	261	Shared Neighborhood Hits	10
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KRA98_HUMAN
NC score	0.079277 (rank : 46)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	15	Target Neighborhood Hits	185	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

NOTC4_HUMAN
NC score	0.077561 (rank : 47)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	905	Shared Neighborhood Hits	12
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

KR104_HUMAN
NC score	0.076961 (rank : 48)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	15	Target Neighborhood Hits	313	Shared Neighborhood Hits	8
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

NOTC2_MOUSE
NC score	0.076672 (rank : 49)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	15	Target Neighborhood Hits	1069	Shared Neighborhood Hits	10
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC2_HUMAN
NC score	0.076492 (rank : 50)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	1113	Shared Neighborhood Hits	11
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

KR107_HUMAN
NC score	0.076335 (rank : 51)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	15	Target Neighborhood Hits	330	Shared Neighborhood Hits	9
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR102_HUMAN
NC score	0.076249 (rank : 52)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	15	Target Neighborhood Hits	264	Shared Neighborhood Hits	9
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

NOTC4_MOUSE
NC score	0.075536 (rank : 53)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	15	Target Neighborhood Hits	872	Shared Neighborhood Hits	11
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

DLK_HUMAN
NC score	0.074542 (rank : 54)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	15	Target Neighborhood Hits	401	Shared Neighborhood Hits	10
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
NC score	0.074202 (rank : 55)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	15	Target Neighborhood Hits	374	Shared Neighborhood Hits	11
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

NOTC3_HUMAN
NC score	0.073801 (rank : 56)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	15	Target Neighborhood Hits	1062	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

EGFL9_HUMAN
NC score	0.073377 (rank : 57)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	15	Target Neighborhood Hits	365	Shared Neighborhood Hits	9
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

NOTC1_HUMAN
NC score	0.073369 (rank : 58)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	15	Target Neighborhood Hits	906	Shared Neighborhood Hits	10
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

JAG2_HUMAN
NC score	0.073302 (rank : 59)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	15	Target Neighborhood Hits	491	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

NOTC3_MOUSE
NC score	0.073270 (rank : 60)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	15	Target Neighborhood Hits	975	Shared Neighborhood Hits	10
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

JAG2_MOUSE
NC score	0.073121 (rank : 61)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	15	Target Neighborhood Hits	504	Shared Neighborhood Hits	10
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

EGFL9_MOUSE
NC score	0.072925 (rank : 62)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	15	Target Neighborhood Hits	379	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

LCE5A_HUMAN
NC score	0.072894 (rank : 63)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	15	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

NOTC1_MOUSE
NC score	0.072389 (rank : 64)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	15	Target Neighborhood Hits	916	Shared Neighborhood Hits	10
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DLL4_MOUSE
NC score	0.071985 (rank : 65)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	15	Target Neighborhood Hits	440	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

KRA11_HUMAN
NC score	0.071958 (rank : 66)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	15	Target Neighborhood Hits	155	Shared Neighborhood Hits	8
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

DLL4_HUMAN
NC score	0.071855 (rank : 67)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	15	Target Neighborhood Hits	435	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

KRA99_HUMAN
NC score	0.071335 (rank : 68)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	15	Target Neighborhood Hits	173	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

JAG1_HUMAN
NC score	0.071099 (rank : 69)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	15	Target Neighborhood Hits	514	Shared Neighborhood Hits	9
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
NC score	0.070368 (rank : 70)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	15	Target Neighborhood Hits	518	Shared Neighborhood Hits	9
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

KR109_HUMAN
NC score	0.069824 (rank : 71)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	15	Target Neighborhood Hits	226	Shared Neighborhood Hits	7
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

DLL3_MOUSE
NC score	0.069720 (rank : 72)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	15	Target Neighborhood Hits	399	Shared Neighborhood Hits	9
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

TECTA_MOUSE
NC score	0.069151 (rank : 73)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	15	Target Neighborhood Hits	244	Shared Neighborhood Hits	9
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

KRA92_HUMAN
NC score	0.068811 (rank : 74)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	15	Target Neighborhood Hits	198	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

DNER_HUMAN
NC score	0.067727 (rank : 75)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	15	Target Neighborhood Hits	460	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

TECTA_HUMAN
NC score	0.067620 (rank : 76)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	15	Target Neighborhood Hits	239	Shared Neighborhood Hits	9
SwissProt Accessions	O75443	Gene names	TECTA
Domain Architecture
Description	Alpha-tectorin precursor.

KR106_HUMAN
NC score	0.067599 (rank : 77)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	15	Target Neighborhood Hits	347	Shared Neighborhood Hits	8
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

CRUM2_HUMAN
NC score	0.067598 (rank : 78)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	15	Target Neighborhood Hits	453	Shared Neighborhood Hits	9
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

DLL1_MOUSE
NC score	0.067567 (rank : 79)	θ value	θ > 10 (rank : 28)
Query Neighborhood Hits	15	Target Neighborhood Hits	456	Shared Neighborhood Hits	10
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DNER_MOUSE
NC score	0.066620 (rank : 80)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	15	Target Neighborhood Hits	413	Shared Neighborhood Hits	9
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

AGRIN_HUMAN
NC score	0.066509 (rank : 81)	θ value	θ > 10 (rank : 16)
Query Neighborhood Hits	15	Target Neighborhood Hits	582	Shared Neighborhood Hits	11
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

DLL1_HUMAN
NC score	0.066490 (rank : 82)	θ value	θ > 10 (rank : 27)
Query Neighborhood Hits	15	Target Neighborhood Hits	455	Shared Neighborhood Hits	10
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

KR105_HUMAN
NC score	0.066281 (rank : 83)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	15	Target Neighborhood Hits	271	Shared Neighborhood Hits	9
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR510_HUMAN
NC score	0.065765 (rank : 84)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	15	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KRA13_HUMAN
NC score	0.065612 (rank : 85)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	15	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA94_HUMAN
NC score	0.065309 (rank : 86)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	15	Target Neighborhood Hits	204	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

DLL3_HUMAN
NC score	0.065304 (rank : 87)	θ value	θ > 10 (rank : 29)
Query Neighborhood Hits	15	Target Neighborhood Hits	419	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

LAMA5_HUMAN
NC score	0.065298 (rank : 88)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	15	Target Neighborhood Hits	976	Shared Neighborhood Hits	13
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

NELL1_HUMAN
NC score	0.065245 (rank : 89)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	15	Target Neighborhood Hits	451	Shared Neighborhood Hits	9
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

KR10B_HUMAN
NC score	0.064482 (rank : 90)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	15	Target Neighborhood Hits	269	Shared Neighborhood Hits	7
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR108_HUMAN
NC score	0.064340 (rank : 91)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	15	Target Neighborhood Hits	226	Shared Neighborhood Hits	8
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KRA15_HUMAN
NC score	0.064195 (rank : 92)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	15	Target Neighborhood Hits	126	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

TIE2_MOUSE
NC score	0.063321 (rank : 93)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	15	Target Neighborhood Hits	1204	Shared Neighborhood Hits	8
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

CFC1_HUMAN
NC score	0.062997 (rank : 94)	θ value	θ > 10 (rank : 19)
Query Neighborhood Hits	15	Target Neighborhood Hits	148	Shared Neighborhood Hits	6
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

TIE2_HUMAN
NC score	0.062950 (rank : 95)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	15	Target Neighborhood Hits	1192	Shared Neighborhood Hits	8
SwissProt Accessions	Q02763	Gene names	TEK, TIE2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (CD202b antigen).

NELL2_HUMAN
NC score	0.062772 (rank : 96)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	15	Target Neighborhood Hits	449	Shared Neighborhood Hits	10
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

CRUM1_MOUSE
NC score	0.062382 (rank : 97)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	15	Target Neighborhood Hits	444	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

NELL2_MOUSE
NC score	0.062375 (rank : 98)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	15	Target Neighborhood Hits	436	Shared Neighborhood Hits	11
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

TENX_HUMAN
NC score	0.062358 (rank : 99)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	15	Target Neighborhood Hits	789	Shared Neighborhood Hits	10
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

FBN3_HUMAN
NC score	0.061634 (rank : 100)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	15	Target Neighborhood Hits	543	Shared Neighborhood Hits	11
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

KRA45_HUMAN
NC score	0.061582 (rank : 101)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	15	Target Neighborhood Hits	194	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

CRUM1_HUMAN
NC score	0.061489 (rank : 102)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	15	Target Neighborhood Hits	457	Shared Neighborhood Hits	9
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

HHIP_HUMAN
NC score	0.061381 (rank : 103)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	15	Target Neighborhood Hits	249	Shared Neighborhood Hits	8
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

MUC5B_HUMAN
NC score	0.060933 (rank : 104)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	15	Target Neighborhood Hits	1020	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

LTBP4_MOUSE
NC score	0.060395 (rank : 105)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	15	Target Neighborhood Hits	607	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

BMPER_HUMAN
NC score	0.060284 (rank : 106)	θ value	θ > 10 (rank : 17)
Query Neighborhood Hits	15	Target Neighborhood Hits	175	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

KR412_HUMAN
NC score	0.060276 (rank : 107)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	15	Target Neighborhood Hits	178	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

TENA_HUMAN
NC score	0.060218 (rank : 108)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	15	Target Neighborhood Hits	631	Shared Neighborhood Hits	10
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

KR10C_HUMAN
NC score	0.059951 (rank : 109)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	15	Target Neighborhood Hits	219	Shared Neighborhood Hits	8
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

LAMA5_MOUSE
NC score	0.059035 (rank : 110)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	15	Target Neighborhood Hits	828	Shared Neighborhood Hits	9
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

FBN1_HUMAN
NC score	0.058692 (rank : 111)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	15	Target Neighborhood Hits	557	Shared Neighborhood Hits	10
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
NC score	0.058667 (rank : 112)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	15	Target Neighborhood Hits	560	Shared Neighborhood Hits	10
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_MOUSE
NC score	0.058268 (rank : 113)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	15	Target Neighborhood Hits	563	Shared Neighborhood Hits	10
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

PCSK5_MOUSE
NC score	0.058046 (rank : 114)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	15	Target Neighborhood Hits	613	Shared Neighborhood Hits	9
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

VWF_MOUSE
NC score	0.057971 (rank : 115)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	15	Target Neighborhood Hits	381	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

TENA_MOUSE
NC score	0.057566 (rank : 116)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	15	Target Neighborhood Hits	596	Shared Neighborhood Hits	10
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

HHIP_MOUSE
NC score	0.057483 (rank : 117)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	15	Target Neighborhood Hits	219	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

MEGF8_MOUSE
NC score	0.057244 (rank : 118)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	15	Target Neighborhood Hits	520	Shared Neighborhood Hits	10
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

FBN2_MOUSE
NC score	0.056985 (rank : 119)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	15	Target Neighborhood Hits	549	Shared Neighborhood Hits	10
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

SPR2I_MOUSE
NC score	0.056585 (rank : 120)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	15	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	O70560	Gene names	Sprr2i
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2I.

MEGF8_HUMAN
NC score	0.056493 (rank : 121)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	15	Target Neighborhood Hits	528	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

KRA93_HUMAN
NC score	0.056243 (rank : 122)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	15	Target Neighborhood Hits	203	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

SSPO_MOUSE
NC score	0.056022 (rank : 123)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	15	Target Neighborhood Hits	800	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

EDIL3_MOUSE
NC score	0.055281 (rank : 124)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	15	Target Neighborhood Hits	317	Shared Neighborhood Hits	8
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

KRA47_HUMAN
NC score	0.055024 (rank : 125)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	15	Target Neighborhood Hits	204	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA44_HUMAN
NC score	0.054898 (rank : 126)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	15	Target Neighborhood Hits	162	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

EDIL3_HUMAN
NC score	0.054518 (rank : 127)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	15	Target Neighborhood Hits	292	Shared Neighborhood Hits	8
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

VWF_HUMAN
NC score	0.054298 (rank : 128)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	15	Target Neighborhood Hits	396	Shared Neighborhood Hits	9
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

LAMB2_HUMAN
NC score	0.054197 (rank : 129)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	15	Target Neighborhood Hits	692	Shared Neighborhood Hits	8
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

MEGF9_MOUSE
NC score	0.053896 (rank : 130)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	15	Target Neighborhood Hits	896	Shared Neighborhood Hits	9
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

KR414_HUMAN
NC score	0.053890 (rank : 131)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	15	Target Neighborhood Hits	199	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

ITB4_HUMAN
NC score	0.053354 (rank : 132)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	15	Target Neighborhood Hits	458	Shared Neighborhood Hits	8
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

BMPER_MOUSE
NC score	0.053221 (rank : 133)	θ value	θ > 10 (rank : 18)
Query Neighborhood Hits	15	Target Neighborhood Hits	194	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

LTBP3_HUMAN
NC score	0.053218 (rank : 134)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	15	Target Neighborhood Hits	502	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

EGFL7_HUMAN
NC score	0.053008 (rank : 135)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	15	Target Neighborhood Hits	325	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

SPR2F_MOUSE
NC score	0.052800 (rank : 136)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	15	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	O70557	Gene names	Sprr2f
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2F.

MEGF9_HUMAN
NC score	0.052196 (rank : 137)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	15	Target Neighborhood Hits	557	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

EGFL7_MOUSE
NC score	0.051688 (rank : 138)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	15	Target Neighborhood Hits	287	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

SPR2D_MOUSE
NC score	0.051602 (rank : 139)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	15	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	O70555	Gene names	Sprr2d
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2D.

ESM1_MOUSE
NC score	0.051060 (rank : 140)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	15	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QYY7	Gene names	Esm1
Domain Architecture
Description	Endothelial cell-specific molecule 1 precursor (ESM-1 secretory protein) (ESM-1).

LTBP2_HUMAN
NC score	0.051032 (rank : 141)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	15	Target Neighborhood Hits	552	Shared Neighborhood Hits	10
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

CUBN_HUMAN
NC score	0.050808 (rank : 142)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	15	Target Neighborhood Hits	482	Shared Neighborhood Hits	10
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

SPR2E_MOUSE
NC score	0.050771 (rank : 143)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	15	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	O70556	Gene names	Sprr2e
Domain Architecture	No domain graphic available
Description	Small proline-rich protein 2E.

LTBP2_MOUSE
NC score	0.050757 (rank : 144)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	15	Target Neighborhood Hits	617	Shared Neighborhood Hits	9
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

CUBN_MOUSE
NC score	0.050382 (rank : 145)	θ value	θ > 10 (rank : 24)
Query Neighborhood Hits	15	Target Neighborhood Hits	477	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

LAMB2_MOUSE
NC score	0.050281 (rank : 146)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	15	Target Neighborhood Hits	722	Shared Neighborhood Hits	8
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

ADA32_MOUSE
NC score	0.028303 (rank : 147)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	219	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K410, Q6P901, Q8BJ80	Gene names	Adam32
Domain Architecture	No domain graphic available
Description	ADAM 32 precursor (A disintegrin and metalloproteinase domain 32).