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Network neighborhood for query Sequence : FREM3_MOUSE

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FREM3_MOUSE
SwissProt Accessions	Q5H8B9	Gene names	Frem3, Nv2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor (NV domain- containing protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FREM1_HUMAN
θ value	0 (rank : 1)	NC score	0.869829 (rank : 5)
Query Neighborhood Hits	49	Target Neighborhood Hits	170	Shared Neighborhood Hits	21
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FREM1_MOUSE
θ value	0 (rank : 2)	NC score	0.856969 (rank : 6)
Query Neighborhood Hits	49	Target Neighborhood Hits	163	Shared Neighborhood Hits	22
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FREM2_HUMAN
θ value	0 (rank : 3)	NC score	0.986282 (rank : 3)
Query Neighborhood Hits	49	Target Neighborhood Hits	76	Shared Neighborhood Hits	22
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

FREM2_MOUSE
θ value	0 (rank : 4)	NC score	0.985262 (rank : 4)
Query Neighborhood Hits	49	Target Neighborhood Hits	73	Shared Neighborhood Hits	24
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

FREM3_HUMAN
θ value	0 (rank : 5)	NC score	0.994776 (rank : 2)
Query Neighborhood Hits	49	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

FREM3_MOUSE
θ value	0 (rank : 6)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	49	Target Neighborhood Hits	49	Shared Neighborhood Hits	49
SwissProt Accessions	Q5H8B9	Gene names	Frem3, Nv2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor (NV domain- containing protein 2).

FRAS1_HUMAN
θ value	1.36511e-173 (rank : 7)	NC score	0.644265 (rank : 9)
Query Neighborhood Hits	49	Target Neighborhood Hits	759	Shared Neighborhood Hits	21
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_MOUSE
θ value	1.51281e-164 (rank : 8)	NC score	0.638378 (rank : 10)
Query Neighborhood Hits	49	Target Neighborhood Hits	747	Shared Neighborhood Hits	21
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

CSPG4_MOUSE
θ value	2.25659e-51 (rank : 9)	NC score	0.707684 (rank : 8)
Query Neighborhood Hits	49	Target Neighborhood Hits	105	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

CSPG4_HUMAN
θ value	9.81109e-47 (rank : 10)	NC score	0.718976 (rank : 7)
Query Neighborhood Hits	49	Target Neighborhood Hits	112	Shared Neighborhood Hits	14
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

NAC3_HUMAN
θ value	1.58096e-12 (rank : 11)	NC score	0.376838 (rank : 13)
Query Neighborhood Hits	49	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	P57103, Q8IUE9, Q8IUF0, Q8NFI7	Gene names	SLC8A3, NCX3
Domain Architecture
Description	Sodium/calcium exchanger 3 precursor (Na(+)/Ca(2+)-exchange protein 3).

GPR98_MOUSE
θ value	1.02475e-11 (rank : 12)	NC score	0.316587 (rank : 15)
Query Neighborhood Hits	49	Target Neighborhood Hits	206	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

NAC1_HUMAN
θ value	4.30538e-10 (rank : 13)	NC score	0.392581 (rank : 11)
Query Neighborhood Hits	49	Target Neighborhood Hits	43	Shared Neighborhood Hits	15
SwissProt Accessions	P32418, O95849, Q9UBL8, Q9UDN1, Q9UDN2, Q9UKX6	Gene names	SLC8A1, CNC, NCX1
Domain Architecture
Description	Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1).

GPR98_HUMAN
θ value	7.34386e-10 (rank : 14)	NC score	0.304159 (rank : 16)
Query Neighborhood Hits	49	Target Neighborhood Hits	202	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

NAC1_MOUSE
θ value	3.64472e-09 (rank : 15)	NC score	0.385294 (rank : 12)
Query Neighborhood Hits	49	Target Neighborhood Hits	41	Shared Neighborhood Hits	15
SwissProt Accessions	P70414	Gene names	Slc8a1, Ncx
Domain Architecture
Description	Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1).

NAC2_HUMAN
θ value	6.21693e-09 (rank : 16)	NC score	0.349006 (rank : 14)
Query Neighborhood Hits	49	Target Neighborhood Hits	33	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPR5	Gene names	SLC8A2, KIAA1087, NCX2
Domain Architecture
Description	Sodium/calcium exchanger 2 precursor (Na(+)/Ca(2+)-exchange protein 2).

ITB4_HUMAN
θ value	0.000602161 (rank : 17)	NC score	0.092093 (rank : 17)
Query Neighborhood Hits	49	Target Neighborhood Hits	458	Shared Neighborhood Hits	17
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

FAT2_HUMAN
θ value	0.00102713 (rank : 18)	NC score	0.040207 (rank : 59)
Query Neighborhood Hits	49	Target Neighborhood Hits	507	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

K0319_HUMAN
θ value	0.125558 (rank : 19)	NC score	0.040280 (rank : 58)
Query Neighborhood Hits	49	Target Neighborhood Hits	154	Shared Neighborhood Hits	7
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

PGFRB_HUMAN
θ value	0.365318 (rank : 20)	NC score	0.002669 (rank : 85)
Query Neighborhood Hits	49	Target Neighborhood Hits	962	Shared Neighborhood Hits	4
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

PCD15_MOUSE
θ value	0.47712 (rank : 21)	NC score	0.025574 (rank : 65)
Query Neighborhood Hits	49	Target Neighborhood Hits	262	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

PCD15_HUMAN
θ value	0.62314 (rank : 22)	NC score	0.031566 (rank : 62)
Query Neighborhood Hits	49	Target Neighborhood Hits	289	Shared Neighborhood Hits	17
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

CAD26_MOUSE
θ value	1.06291 (rank : 23)	NC score	0.020894 (rank : 67)
Query Neighborhood Hits	49	Target Neighborhood Hits	153	Shared Neighborhood Hits	15
SwissProt Accessions	P59862	Gene names	Cdh26
Domain Architecture
Description	Cadherin-like protein 26 precursor.

PGBM_HUMAN
θ value	1.06291 (rank : 24)	NC score	0.025705 (rank : 64)
Query Neighborhood Hits	49	Target Neighborhood Hits	1113	Shared Neighborhood Hits	14
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

DSC1_MOUSE
θ value	1.38821 (rank : 25)	NC score	0.014514 (rank : 72)
Query Neighborhood Hits	49	Target Neighborhood Hits	150	Shared Neighborhood Hits	14
SwissProt Accessions	P55849	Gene names	Dsc1
Domain Architecture
Description	Desmocollin-1 precursor.

K0319_MOUSE
θ value	1.38821 (rank : 26)	NC score	0.031815 (rank : 61)
Query Neighborhood Hits	49	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

PCD16_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.026700 (rank : 63)
Query Neighborhood Hits	49	Target Neighborhood Hits	245	Shared Neighborhood Hits	23
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

PCDBB_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.020464 (rank : 68)
Query Neighborhood Hits	49	Target Neighborhood Hits	159	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5F2	Gene names	PCDHB11
Domain Architecture
Description	Protocadherin beta 11 precursor (PCDH-beta11).

FA5_HUMAN
θ value	1.81305 (rank : 29)	NC score	0.010633 (rank : 73)
Query Neighborhood Hits	49	Target Neighborhood Hits	172	Shared Neighborhood Hits	6
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

UNC5B_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.009437 (rank : 75)
Query Neighborhood Hits	49	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

CD45_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.004454 (rank : 81)
Query Neighborhood Hits	49	Target Neighborhood Hits	243	Shared Neighborhood Hits	4
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

PCDB2_HUMAN
θ value	2.36792 (rank : 32)	NC score	0.014591 (rank : 71)
Query Neighborhood Hits	49	Target Neighborhood Hits	159	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y5E7	Gene names	PCDHB2
Domain Architecture
Description	Protocadherin beta 2 precursor (PCDH-beta2).

PCDLK_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.024833 (rank : 66)
Query Neighborhood Hits	49	Target Neighborhood Hits	172	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BYE9, Q9NXP8	Gene names	PCLKC
Domain Architecture	No domain graphic available
Description	Protocadherin LKC precursor (PC-LKC).

DMXL1_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.008811 (rank : 78)
Query Neighborhood Hits	49	Target Neighborhood Hits	259	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

PCDGE_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.014789 (rank : 70)
Query Neighborhood Hits	49	Target Neighborhood Hits	164	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y5G2, Q9UN65	Gene names	PCDHGB2
Domain Architecture
Description	Protocadherin gamma B2 precursor (PCDH-gamma-B2).

UNC5B_MOUSE
θ value	3.0926 (rank : 36)	NC score	0.008848 (rank : 77)
Query Neighborhood Hits	49	Target Neighborhood Hits	226	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

CAD23_MOUSE
θ value	4.03905 (rank : 37)	NC score	0.033689 (rank : 60)
Query Neighborhood Hits	49	Target Neighborhood Hits	208	Shared Neighborhood Hits	24
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

KI13A_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.003014 (rank : 84)
Query Neighborhood Hits	49	Target Neighborhood Hits	359	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H1H9, Q9H1H8	Gene names	KIF13A, RBKIN
Domain Architecture
Description	Kinesin-like protein KIF13A (Kinesin-like protein RBKIN).

MFGM_MOUSE
θ value	4.03905 (rank : 39)	NC score	0.009716 (rank : 74)
Query Neighborhood Hits	49	Target Neighborhood Hits	233	Shared Neighborhood Hits	6
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

WBP11_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.009394 (rank : 76)
Query Neighborhood Hits	49	Target Neighborhood Hits	362	Shared Neighborhood Hits	2
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

JIP2_MOUSE
θ value	5.27518 (rank : 41)	NC score	0.008504 (rank : 79)
Query Neighborhood Hits	49	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

SPAG5_HUMAN
θ value	5.27518 (rank : 42)	NC score	0.003807 (rank : 82)
Query Neighborhood Hits	49	Target Neighborhood Hits	625	Shared Neighborhood Hits	2
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

NMD3B_HUMAN
θ value	6.88961 (rank : 43)	NC score	0.003665 (rank : 83)
Query Neighborhood Hits	49	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

AAK1_MOUSE
θ value	8.99809 (rank : 44)	NC score	-0.000049 (rank : 89)
Query Neighborhood Hits	49	Target Neighborhood Hits	1051	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

CAD24_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.020179 (rank : 69)
Query Neighborhood Hits	49	Target Neighborhood Hits	166	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UP0, Q86UP1, Q9NT84	Gene names	CDH24, CDH11L
Domain Architecture
Description	Cadherin-24 precursor.

COHA1_MOUSE
θ value	8.99809 (rank : 46)	NC score	0.002033 (rank : 86)
Query Neighborhood Hits	49	Target Neighborhood Hits	414	Shared Neighborhood Hits	3
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

GCR_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.001624 (rank : 88)
Query Neighborhood Hits	49	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

TEP1_HUMAN
θ value	8.99809 (rank : 48)	NC score	0.001976 (rank : 87)
Query Neighborhood Hits	49	Target Neighborhood Hits	371	Shared Neighborhood Hits	3
SwissProt Accessions	Q99973	Gene names	TEP1, TLP1, TP1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog).

ZC11A_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.006436 (rank : 80)
Query Neighborhood Hits	49	Target Neighborhood Hits	170	Shared Neighborhood Hits	2
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

BMPER_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.090001 (rank : 19)
Query Neighborhood Hits	49	Target Neighborhood Hits	175	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

BMPER_MOUSE
θ value	θ > 10 (rank : 51)	NC score	0.084464 (rank : 22)
Query Neighborhood Hits	49	Target Neighborhood Hits	194	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

CHRD_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.090317 (rank : 18)
Query Neighborhood Hits	49	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

CHRD_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.085544 (rank : 20)
Query Neighborhood Hits	49	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CRDL1_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.070875 (rank : 28)
Query Neighborhood Hits	49	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL1_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.064216 (rank : 34)
Query Neighborhood Hits	49	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL2_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.070866 (rank : 29)
Query Neighborhood Hits	49	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

CRDL2_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.066399 (rank : 31)
Query Neighborhood Hits	49	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

CRIM1_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.084796 (rank : 21)
Query Neighborhood Hits	49	Target Neighborhood Hits	362	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

KR101_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.057607 (rank : 43)
Query Neighborhood Hits	49	Target Neighborhood Hits	261	Shared Neighborhood Hits	2
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR104_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.061430 (rank : 38)
Query Neighborhood Hits	49	Target Neighborhood Hits	313	Shared Neighborhood Hits	2
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.051822 (rank : 50)
Query Neighborhood Hits	49	Target Neighborhood Hits	271	Shared Neighborhood Hits	2
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR107_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.057939 (rank : 42)
Query Neighborhood Hits	49	Target Neighborhood Hits	330	Shared Neighborhood Hits	2
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR108_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.065725 (rank : 33)
Query Neighborhood Hits	49	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.051306 (rank : 53)
Query Neighborhood Hits	49	Target Neighborhood Hits	226	Shared Neighborhood Hits	2
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR410_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.055621 (rank : 45)
Query Neighborhood Hits	49	Target Neighborhood Hits	156	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

KR510_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.066163 (rank : 32)
Query Neighborhood Hits	49	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KRA45_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.052406 (rank : 48)
Query Neighborhood Hits	49	Target Neighborhood Hits	194	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA47_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.051821 (rank : 51)
Query Neighborhood Hits	49	Target Neighborhood Hits	204	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA51_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.081993 (rank : 25)
Query Neighborhood Hits	49	Target Neighborhood Hits	288	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.083751 (rank : 23)
Query Neighborhood Hits	49	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA53_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.056652 (rank : 44)
Query Neighborhood Hits	49	Target Neighborhood Hits	331	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.082298 (rank : 24)
Query Neighborhood Hits	49	Target Neighborhood Hits	270	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.080502 (rank : 26)
Query Neighborhood Hits	49	Target Neighborhood Hits	257	Shared Neighborhood Hits	3
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA56_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.068248 (rank : 30)
Query Neighborhood Hits	49	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

KRA57_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.060123 (rank : 40)
Query Neighborhood Hits	49	Target Neighborhood Hits	269	Shared Neighborhood Hits	3
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.050278 (rank : 56)
Query Neighborhood Hits	49	Target Neighborhood Hits	324	Shared Neighborhood Hits	4
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.058751 (rank : 41)
Query Neighborhood Hits	49	Target Neighborhood Hits	310	Shared Neighborhood Hits	4
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

LCE5A_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.052274 (rank : 49)
Query Neighborhood Hits	49	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

PCSK5_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.062863 (rank : 35)
Query Neighborhood Hits	49	Target Neighborhood Hits	291	Shared Neighborhood Hits	3
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

PCSK5_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.079506 (rank : 27)
Query Neighborhood Hits	49	Target Neighborhood Hits	613	Shared Neighborhood Hits	4
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PCSK6_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.061179 (rank : 39)
Query Neighborhood Hits	49	Target Neighborhood Hits	298	Shared Neighborhood Hits	3
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

REG3G_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.050931 (rank : 54)
Query Neighborhood Hits	49	Target Neighborhood Hits	91	Shared Neighborhood Hits	2
SwissProt Accessions	O09049	Gene names	Reg3g, Pap3
Domain Architecture
Description	Regenerating islet-derived protein 3 gamma precursor (Reg III-gamma) (Pancreatitis-associated protein 3).

RSPO2_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.054781 (rank : 46)
Query Neighborhood Hits	49	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO2_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.054407 (rank : 47)
Query Neighborhood Hits	49	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

RSPO3_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.051518 (rank : 52)
Query Neighborhood Hits	49	Target Neighborhood Hits	128	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

RSPO3_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.050908 (rank : 55)
Query Neighborhood Hits	49	Target Neighborhood Hits	120	Shared Neighborhood Hits	2
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

RSPO4_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.061935 (rank : 37)
Query Neighborhood Hits	49	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

RSPO4_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.062211 (rank : 36)
Query Neighborhood Hits	49	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

ZAN_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.050229 (rank : 57)
Query Neighborhood Hits	49	Target Neighborhood Hits	808	Shared Neighborhood Hits	8
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

FREM3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 6)
Query Neighborhood Hits	49	Target Neighborhood Hits	49	Shared Neighborhood Hits	49
SwissProt Accessions	Q5H8B9	Gene names	Frem3, Nv2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor (NV domain- containing protein 2).

FREM3_HUMAN
NC score	0.994776 (rank : 2)	θ value	0 (rank : 5)
Query Neighborhood Hits	49	Target Neighborhood Hits	56	Shared Neighborhood Hits	22
SwissProt Accessions	P0C091	Gene names	FREM3
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 3 precursor.

FREM2_HUMAN
NC score	0.986282 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	49	Target Neighborhood Hits	76	Shared Neighborhood Hits	22
SwissProt Accessions	Q5SZK8, Q4QQG1, Q5H9N8, Q5T6Q1, Q6N057, Q6ZSB4, Q7Z305, Q7Z341	Gene names	FREM2
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog).

FREM2_MOUSE
NC score	0.985262 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	49	Target Neighborhood Hits	73	Shared Neighborhood Hits	24
SwissProt Accessions	Q6NVD0, Q4W2Q5, Q5H8C0, Q811G9, Q8C4G5, Q8CD46	Gene names	Frem2, Nv1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 2 precursor (ECM3 homolog) (NV domain-containing protein 1).

FREM1_HUMAN
NC score	0.869829 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	49	Target Neighborhood Hits	170	Shared Neighborhood Hits	21
SwissProt Accessions	Q5H8C1, Q5VV00, Q5VV01, Q6MZI4, Q8NEG9, Q96LI3	Gene names	FREM1, C9orf154
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

FREM1_MOUSE
NC score	0.856969 (rank : 6)	θ value	0 (rank : 2)
Query Neighborhood Hits	49	Target Neighborhood Hits	163	Shared Neighborhood Hits	22
SwissProt Accessions	Q684R7, Q5H8C2, Q5M7B3, Q8C732	Gene names	Frem1
Domain Architecture	No domain graphic available
Description	FRAS1-related extracellular matrix protein 1 precursor (Protein QBRICK).

CSPG4_HUMAN
NC score	0.718976 (rank : 7)	θ value	9.81109e-47 (rank : 10)
Query Neighborhood Hits	49	Target Neighborhood Hits	112	Shared Neighborhood Hits	14
SwissProt Accessions	Q6UVK1, Q92675	Gene names	CSPG4, MCSP
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (Melanoma chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate proteoglycan).

CSPG4_MOUSE
NC score	0.707684 (rank : 8)	θ value	2.25659e-51 (rank : 9)
Query Neighborhood Hits	49	Target Neighborhood Hits	105	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VHY0, Q5DTG1, Q8BPI8, Q8CE79	Gene names	Cspg4, An2, Kiaa4232, Ng2
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (AN2 proteoglycan).

FRAS1_HUMAN
NC score	0.644265 (rank : 9)	θ value	1.36511e-173 (rank : 7)
Query Neighborhood Hits	49	Target Neighborhood Hits	759	Shared Neighborhood Hits	21
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_MOUSE
NC score	0.638378 (rank : 10)	θ value	1.51281e-164 (rank : 8)
Query Neighborhood Hits	49	Target Neighborhood Hits	747	Shared Neighborhood Hits	21
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

NAC1_HUMAN
NC score	0.392581 (rank : 11)	θ value	4.30538e-10 (rank : 13)
Query Neighborhood Hits	49	Target Neighborhood Hits	43	Shared Neighborhood Hits	15
SwissProt Accessions	P32418, O95849, Q9UBL8, Q9UDN1, Q9UDN2, Q9UKX6	Gene names	SLC8A1, CNC, NCX1
Domain Architecture
Description	Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1).

NAC1_MOUSE
NC score	0.385294 (rank : 12)	θ value	3.64472e-09 (rank : 15)
Query Neighborhood Hits	49	Target Neighborhood Hits	41	Shared Neighborhood Hits	15
SwissProt Accessions	P70414	Gene names	Slc8a1, Ncx
Domain Architecture
Description	Sodium/calcium exchanger 1 precursor (Na(+)/Ca(2+)-exchange protein 1).

NAC3_HUMAN
NC score	0.376838 (rank : 13)	θ value	1.58096e-12 (rank : 11)
Query Neighborhood Hits	49	Target Neighborhood Hits	42	Shared Neighborhood Hits	15
SwissProt Accessions	P57103, Q8IUE9, Q8IUF0, Q8NFI7	Gene names	SLC8A3, NCX3
Domain Architecture
Description	Sodium/calcium exchanger 3 precursor (Na(+)/Ca(2+)-exchange protein 3).

NAC2_HUMAN
NC score	0.349006 (rank : 14)	θ value	6.21693e-09 (rank : 16)
Query Neighborhood Hits	49	Target Neighborhood Hits	33	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UPR5	Gene names	SLC8A2, KIAA1087, NCX2
Domain Architecture
Description	Sodium/calcium exchanger 2 precursor (Na(+)/Ca(2+)-exchange protein 2).

GPR98_MOUSE
NC score	0.316587 (rank : 15)	θ value	1.02475e-11 (rank : 12)
Query Neighborhood Hits	49	Target Neighborhood Hits	206	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VHN7, Q6ZQ69, Q810D2, Q810D3, Q91ZS0, Q91ZS1	Gene names	Gpr98, Kiaa0686, Mass1, Vlgr1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1) (Very large G-protein coupled receptor 1) (Neurepin).

GPR98_HUMAN
NC score	0.304159 (rank : 16)	θ value	7.34386e-10 (rank : 14)
Query Neighborhood Hits	49	Target Neighborhood Hits	202	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

ITB4_HUMAN
NC score	0.092093 (rank : 17)	θ value	0.000602161 (rank : 17)
Query Neighborhood Hits	49	Target Neighborhood Hits	458	Shared Neighborhood Hits	17
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

CHRD_HUMAN
NC score	0.090317 (rank : 18)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	49	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H2X0, O95254, Q6UW83, Q9H2D3, Q9H2W8, Q9H2W9, Q9P0Z2, Q9P0Z3, Q9P0Z4, Q9P0Z5	Gene names	CHRD
Domain Architecture
Description	Chordin precursor.

BMPER_HUMAN
NC score	0.090001 (rank : 19)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	49	Target Neighborhood Hits	175	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N8U9	Gene names	BMPER
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2).

CHRD_MOUSE
NC score	0.085544 (rank : 20)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	49	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0E2	Gene names	Chrd
Domain Architecture
Description	Chordin precursor.

CRIM1_HUMAN
NC score	0.084796 (rank : 21)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	49	Target Neighborhood Hits	362	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

BMPER_MOUSE
NC score	0.084464 (rank : 22)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	49	Target Neighborhood Hits	194	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CJ69, Q7TN57, Q80UZ1, Q9CXM8	Gene names	Bmper, Cv2
Domain Architecture
Description	BMP-binding endothelial regulator protein precursor (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (mCV2).

KRA52_HUMAN
NC score	0.083751 (rank : 23)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	49	Target Neighborhood Hits	236	Shared Neighborhood Hits	4
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA54_HUMAN
NC score	0.082298 (rank : 24)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	49	Target Neighborhood Hits	270	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA51_HUMAN
NC score	0.081993 (rank : 25)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	49	Target Neighborhood Hits	288	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA55_HUMAN
NC score	0.080502 (rank : 26)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	49	Target Neighborhood Hits	257	Shared Neighborhood Hits	3
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

PCSK5_MOUSE
NC score	0.079506 (rank : 27)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	49	Target Neighborhood Hits	613	Shared Neighborhood Hits	4
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

CRDL1_HUMAN
NC score	0.070875 (rank : 28)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	49	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BU40, Q9Y3H7	Gene names	CHRDL1, NRLN1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

CRDL2_HUMAN
NC score	0.070866 (rank : 29)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	49	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	Q6WN34, Q6WN30, Q6WN31, Q6WN32, Q7Z5J3	Gene names	CHRDL2, BNF1, CHL2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor (Chordin-related protein 2) (Breast tumor novel factor 1) (BNF-1).

KRA56_HUMAN
NC score	0.068248 (rank : 30)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	49	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8G9	Gene names	KRTAP5-6, KAP5.6, KRTAP5.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-6 (Keratin-associated protein 5.6) (Ultrahigh sulfur keratin-associated protein 5.6).

CRDL2_MOUSE
NC score	0.066399 (rank : 31)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	49	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VEA6, Q925I3	Gene names	Chrdl2, Chl2
Domain Architecture	No domain graphic available
Description	Chordin-like protein 2 precursor.

KR510_HUMAN
NC score	0.066163 (rank : 32)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	49	Target Neighborhood Hits	217	Shared Neighborhood Hits	3
SwissProt Accessions	Q6L8G5	Gene names	KRTAP5-10, KAP5.10, KRTAP5.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-10 (Keratin-associated protein 5.10) (Ultrahigh sulfur keratin-associated protein 5.10).

KR108_HUMAN
NC score	0.065725 (rank : 33)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	49	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

CRDL1_MOUSE
NC score	0.064216 (rank : 34)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	49	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q920C1, Q924K0, Q9EPZ9	Gene names	Chrdl1, Ng1, Nrln1
Domain Architecture
Description	Chordin-like protein 1 precursor (Neuralin-1) (Ventroptin) (Neurogenesin-1).

PCSK5_HUMAN
NC score	0.062863 (rank : 35)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	49	Target Neighborhood Hits	291	Shared Neighborhood Hits	3
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

RSPO4_MOUSE
NC score	0.062211 (rank : 36)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	49	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJ73	Gene names	Rspo4
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (Cysteine-rich and single thrombospondin domain-containing protein 4) (Cristin-4) (mCristin-4).

RSPO4_HUMAN
NC score	0.061935 (rank : 37)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	49	Target Neighborhood Hits	110	Shared Neighborhood Hits	2
SwissProt Accessions	Q2I0M5, Q9UGB2	Gene names	RSPO4, C20orf182
Domain Architecture	No domain graphic available
Description	R-spondin-4 precursor (Roof plate-specific spondin-4) (hRspo4).

KR104_HUMAN
NC score	0.061430 (rank : 38)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	49	Target Neighborhood Hits	313	Shared Neighborhood Hits	2
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

PCSK6_HUMAN
NC score	0.061179 (rank : 39)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	49	Target Neighborhood Hits	298	Shared Neighborhood Hits	3
SwissProt Accessions	P29122, Q15099, Q15100, Q9UEG7, Q9UEJ1, Q9UEJ2, Q9UEJ7, Q9UEJ8, Q9UEJ9, Q9Y4G9, Q9Y4H0, Q9Y4H1	Gene names	PCSK6, PACE4
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 6 precursor (EC 3.4.21.-) (Paired basic amino acid cleaving enzyme 4) (Subtilisin/kexin-like protease PACE4) (Subtilisin-like proprotein convertase 4) (SPC4).

KRA57_HUMAN
NC score	0.060123 (rank : 40)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	49	Target Neighborhood Hits	269	Shared Neighborhood Hits	3
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA59_HUMAN
NC score	0.058751 (rank : 41)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	49	Target Neighborhood Hits	310	Shared Neighborhood Hits	4
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KR107_HUMAN
NC score	0.057939 (rank : 42)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	49	Target Neighborhood Hits	330	Shared Neighborhood Hits	2
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR101_HUMAN
NC score	0.057607 (rank : 43)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	49	Target Neighborhood Hits	261	Shared Neighborhood Hits	2
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KRA53_HUMAN
NC score	0.056652 (rank : 44)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	49	Target Neighborhood Hits	331	Shared Neighborhood Hits	4
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KR410_HUMAN
NC score	0.055621 (rank : 45)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	49	Target Neighborhood Hits	156	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYQ7	Gene names	KRTAP4-10, KAP4.10, KRTAP4.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-10 (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10).

RSPO2_HUMAN
NC score	0.054781 (rank : 46)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	49	Target Neighborhood Hits	90	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UXX9, Q4G0U4, Q8N6X6	Gene names	RSPO2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (hRspo2).

RSPO2_MOUSE
NC score	0.054407 (rank : 47)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	49	Target Neighborhood Hits	88	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BFU0, Q7TPX3	Gene names	Rspo2
Domain Architecture	No domain graphic available
Description	R-spondin-2 precursor (Roof plate-specific spondin-2) (Cysteine-rich and single thrombospondin domain-containing protein 2) (Cristin-2) (mCristin-2).

KRA45_HUMAN
NC score	0.052406 (rank : 48)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	49	Target Neighborhood Hits	194	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

LCE5A_HUMAN
NC score	0.052274 (rank : 49)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	49	Target Neighborhood Hits	43	Shared Neighborhood Hits	2
SwissProt Accessions	Q5TCM9	Gene names	LCE5A, LEP18, SPRL5A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 5A (Late envelope protein 18) (Small proline-rich-like epidermal differentiation complex protein 5A).

KR105_HUMAN
NC score	0.051822 (rank : 50)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	49	Target Neighborhood Hits	271	Shared Neighborhood Hits	2
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KRA47_HUMAN
NC score	0.051821 (rank : 51)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	49	Target Neighborhood Hits	204	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

RSPO3_HUMAN
NC score	0.051518 (rank : 52)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	49	Target Neighborhood Hits	128	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXY4, Q5VTV4, Q96K87	Gene names	RSPO3, PWTSR, THSD2
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2) (Protein with TSP type-1 repeat) (hPWTSR).

KR109_HUMAN
NC score	0.051306 (rank : 53)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	49	Target Neighborhood Hits	226	Shared Neighborhood Hits	2
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

REG3G_MOUSE
NC score	0.050931 (rank : 54)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	49	Target Neighborhood Hits	91	Shared Neighborhood Hits	2
SwissProt Accessions	O09049	Gene names	Reg3g, Pap3
Domain Architecture
Description	Regenerating islet-derived protein 3 gamma precursor (Reg III-gamma) (Pancreatitis-associated protein 3).

RSPO3_MOUSE
NC score	0.050908 (rank : 55)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	49	Target Neighborhood Hits	120	Shared Neighborhood Hits	2
SwissProt Accessions	Q2TJ95, Q3SYI9, Q5R2V4, Q8BVW2, Q9CSB2	Gene names	Rspo3
Domain Architecture	No domain graphic available
Description	R-spondin-3 precursor (Roof plate-specific spondin-3) (Cysteine-rich and single thrombospondin domain-containing protein 1) (Cristin-1) (Nucleopondin) (Cabriolet).

KRA58_HUMAN
NC score	0.050278 (rank : 56)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	49	Target Neighborhood Hits	324	Shared Neighborhood Hits	4
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

ZAN_MOUSE
NC score	0.050229 (rank : 57)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	49	Target Neighborhood Hits	808	Shared Neighborhood Hits	8
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

K0319_HUMAN
NC score	0.040280 (rank : 58)	θ value	0.125558 (rank : 19)
Query Neighborhood Hits	49	Target Neighborhood Hits	154	Shared Neighborhood Hits	7
SwissProt Accessions	Q5VV43, Q9UJC8, Q9Y4G7	Gene names	KIAA0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

FAT2_HUMAN
NC score	0.040207 (rank : 59)	θ value	0.00102713 (rank : 18)
Query Neighborhood Hits	49	Target Neighborhood Hits	507	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

CAD23_MOUSE
NC score	0.033689 (rank : 60)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	49	Target Neighborhood Hits	208	Shared Neighborhood Hits	24
SwissProt Accessions	Q99PF4, Q99NH1, Q9D4N9	Gene names	Cdh23
Domain Architecture
Description	Cadherin-23 precursor (Otocadherin).

K0319_MOUSE
NC score	0.031815 (rank : 61)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	49	Target Neighborhood Hits	134	Shared Neighborhood Hits	5
SwissProt Accessions	Q5SZV5, Q80U39	Gene names	Kiaa0319
Domain Architecture	No domain graphic available
Description	Protein KIAA0319 precursor.

PCD15_HUMAN
NC score	0.031566 (rank : 62)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	49	Target Neighborhood Hits	289	Shared Neighborhood Hits	17
SwissProt Accessions	Q96QU1, Q96QT8	Gene names	PCDH15
Domain Architecture
Description	Protocadherin-15 precursor.

PCD16_HUMAN
NC score	0.026700 (rank : 63)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	49	Target Neighborhood Hits	245	Shared Neighborhood Hits	23
SwissProt Accessions	Q96JQ0, O15098	Gene names	DCHS1, CDH19, FIB1, KIAA1773, PCDH16
Domain Architecture
Description	Protocadherin-16 precursor (Dachsous 1) (Cadherin-19) (Fibroblast cadherin 1).

PGBM_HUMAN
NC score	0.025705 (rank : 64)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	49	Target Neighborhood Hits	1113	Shared Neighborhood Hits	14
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PCD15_MOUSE
NC score	0.025574 (rank : 65)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	49	Target Neighborhood Hits	262	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PJ1	Gene names	Pcdh15
Domain Architecture
Description	Protocadherin-15 precursor.

PCDLK_HUMAN
NC score	0.024833 (rank : 66)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	49	Target Neighborhood Hits	172	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BYE9, Q9NXP8	Gene names	PCLKC
Domain Architecture	No domain graphic available
Description	Protocadherin LKC precursor (PC-LKC).

CAD26_MOUSE
NC score	0.020894 (rank : 67)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	49	Target Neighborhood Hits	153	Shared Neighborhood Hits	15
SwissProt Accessions	P59862	Gene names	Cdh26
Domain Architecture
Description	Cadherin-like protein 26 precursor.

PCDBB_HUMAN
NC score	0.020464 (rank : 68)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	49	Target Neighborhood Hits	159	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5F2	Gene names	PCDHB11
Domain Architecture
Description	Protocadherin beta 11 precursor (PCDH-beta11).

CAD24_HUMAN
NC score	0.020179 (rank : 69)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	49	Target Neighborhood Hits	166	Shared Neighborhood Hits	16
SwissProt Accessions	Q86UP0, Q86UP1, Q9NT84	Gene names	CDH24, CDH11L
Domain Architecture
Description	Cadherin-24 precursor.

PCDGE_HUMAN
NC score	0.014789 (rank : 70)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	49	Target Neighborhood Hits	164	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y5G2, Q9UN65	Gene names	PCDHGB2
Domain Architecture
Description	Protocadherin gamma B2 precursor (PCDH-gamma-B2).

PCDB2_HUMAN
NC score	0.014591 (rank : 71)	θ value	2.36792 (rank : 32)
Query Neighborhood Hits	49	Target Neighborhood Hits	159	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y5E7	Gene names	PCDHB2
Domain Architecture
Description	Protocadherin beta 2 precursor (PCDH-beta2).

DSC1_MOUSE
NC score	0.014514 (rank : 72)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	49	Target Neighborhood Hits	150	Shared Neighborhood Hits	14
SwissProt Accessions	P55849	Gene names	Dsc1
Domain Architecture
Description	Desmocollin-1 precursor.

FA5_HUMAN
NC score	0.010633 (rank : 73)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	49	Target Neighborhood Hits	172	Shared Neighborhood Hits	6
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

MFGM_MOUSE
NC score	0.009716 (rank : 74)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	49	Target Neighborhood Hits	233	Shared Neighborhood Hits	6
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

UNC5B_HUMAN
NC score	0.009437 (rank : 75)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	49	Target Neighborhood Hits	225	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZJ1, Q86SN3, Q8N1Y2, Q9H9F3	Gene names	UNC5B, P53RDL1, UNC5H2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2) (p53-regulated receptor for death and life protein 1).

WBP11_MOUSE
NC score	0.009394 (rank : 76)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	49	Target Neighborhood Hits	362	Shared Neighborhood Hits	2
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

UNC5B_MOUSE
NC score	0.008848 (rank : 77)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	49	Target Neighborhood Hits	226	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K1S3, Q3U4F2, Q6PFH0, Q80Y85, Q9D398	Gene names	Unc5b, Unc5h2
Domain Architecture	No domain graphic available
Description	Netrin receptor UNC5B precursor (Unc-5 homolog B) (Unc-5 homolog 2).

DMXL1_HUMAN
NC score	0.008811 (rank : 78)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	49	Target Neighborhood Hits	259	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y485	Gene names	DMXL1, XL1
Domain Architecture	No domain graphic available
Description	Protein DmX-like 1 (X-like 1 protein).

JIP2_MOUSE
NC score	0.008504 (rank : 79)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	49	Target Neighborhood Hits	144	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERE9, Q9CXI4	Gene names	Mapk8ip2, Ib2, Jip2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 2 (JNK-interacting protein 2) (JIP-2) (JNK MAP kinase scaffold protein 2) (Islet-brain-2) (IB-2) (Mitogen-activated protein kinase 8-interacting protein 2).

ZC11A_HUMAN
NC score	0.006436 (rank : 80)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	49	Target Neighborhood Hits	170	Shared Neighborhood Hits	2
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

CD45_HUMAN
NC score	0.004454 (rank : 81)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	49	Target Neighborhood Hits	243	Shared Neighborhood Hits	4
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

SPAG5_HUMAN
NC score	0.003807 (rank : 82)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	49	Target Neighborhood Hits	625	Shared Neighborhood Hits	2
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

NMD3B_HUMAN
NC score	0.003665 (rank : 83)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	49	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	O60391, Q5EAK7, Q7RTW9	Gene names	GRIN3B
Domain Architecture	No domain graphic available
Description	Glutamate [NMDA] receptor subunit 3B precursor (N-methyl-D-aspartate receptor subtype NR3B) (NR3B) (NMDAR3B).

KI13A_HUMAN
NC score	0.003014 (rank : 84)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	49	Target Neighborhood Hits	359	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H1H9, Q9H1H8	Gene names	KIF13A, RBKIN
Domain Architecture
Description	Kinesin-like protein KIF13A (Kinesin-like protein RBKIN).

PGFRB_HUMAN
NC score	0.002669 (rank : 85)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	49	Target Neighborhood Hits	962	Shared Neighborhood Hits	4
SwissProt Accessions	P09619, Q8N5L4	Gene names	PDGFRB
Domain Architecture
Description	Beta platelet-derived growth factor receptor precursor (EC 2.7.10.1) (PDGF-R-beta) (CD140b antigen).

COHA1_MOUSE
NC score	0.002033 (rank : 86)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	49	Target Neighborhood Hits	414	Shared Neighborhood Hits	3
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

TEP1_HUMAN
NC score	0.001976 (rank : 87)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	49	Target Neighborhood Hits	371	Shared Neighborhood Hits	3
SwissProt Accessions	Q99973	Gene names	TEP1, TLP1, TP1
Domain Architecture
Description	Telomerase protein component 1 (Telomerase-associated protein 1) (Telomerase protein 1) (p240) (p80 telomerase homolog).

GCR_HUMAN
NC score	0.001624 (rank : 88)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	49	Target Neighborhood Hits	113	Shared Neighborhood Hits	2
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

AAK1_MOUSE
NC score	-0.000049 (rank : 89)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	49	Target Neighborhood Hits	1051	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).