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Network neighborhood for query Sequence : PACS1_MOUSE

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PACS1_MOUSE
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PACS1_HUMAN
θ value	0 (rank : 1)	NC score	0.988326 (rank : 2)
Query Neighborhood Hits	87	Target Neighborhood Hits	82	Shared Neighborhood Hits	55
SwissProt Accessions	Q6VY07, Q6PJY6, Q6PKB6, Q7Z590, Q7Z5W4, Q8N8K6, Q96MW0, Q9NW92, Q9ULP5	Gene names	PACS1, KIAA1175
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

PACS1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	87	Target Neighborhood Hits	87	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

DSPP_HUMAN
θ value	0.00228821 (rank : 3)	NC score	0.115728 (rank : 3)
Query Neighborhood Hits	87	Target Neighborhood Hits	645	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

NFH_HUMAN
θ value	0.00509761 (rank : 4)	NC score	0.059725 (rank : 15)
Query Neighborhood Hits	87	Target Neighborhood Hits	1242	Shared Neighborhood Hits	41
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CASP_MOUSE
θ value	0.00869519 (rank : 5)	NC score	0.073910 (rank : 10)
Query Neighborhood Hits	87	Target Neighborhood Hits	1152	Shared Neighborhood Hits	23
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_HUMAN
θ value	0.0113563 (rank : 6)	NC score	0.072722 (rank : 11)
Query Neighborhood Hits	87	Target Neighborhood Hits	1131	Shared Neighborhood Hits	22
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

AFF4_HUMAN
θ value	0.0148317 (rank : 7)	NC score	0.111413 (rank : 4)
Query Neighborhood Hits	87	Target Neighborhood Hits	611	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

AFF4_MOUSE
θ value	0.163984 (rank : 8)	NC score	0.100714 (rank : 5)
Query Neighborhood Hits	87	Target Neighborhood Hits	581	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

CUTL1_HUMAN
θ value	0.163984 (rank : 9)	NC score	0.066026 (rank : 14)
Query Neighborhood Hits	87	Target Neighborhood Hits	1574	Shared Neighborhood Hits	30
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CUTL1_MOUSE
θ value	0.163984 (rank : 10)	NC score	0.067894 (rank : 13)
Query Neighborhood Hits	87	Target Neighborhood Hits	1620	Shared Neighborhood Hits	33
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

RBBP6_HUMAN
θ value	0.21417 (rank : 11)	NC score	0.069170 (rank : 12)
Query Neighborhood Hits	87	Target Neighborhood Hits	1135	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

FOXE2_HUMAN
θ value	0.279714 (rank : 12)	NC score	0.023652 (rank : 57)
Query Neighborhood Hits	87	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

GP158_HUMAN
θ value	0.279714 (rank : 13)	NC score	0.075833 (rank : 9)
Query Neighborhood Hits	87	Target Neighborhood Hits	221	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

TBX21_MOUSE
θ value	0.279714 (rank : 14)	NC score	0.035794 (rank : 37)
Query Neighborhood Hits	87	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

TP53B_MOUSE
θ value	0.279714 (rank : 15)	NC score	0.080327 (rank : 7)
Query Neighborhood Hits	87	Target Neighborhood Hits	644	Shared Neighborhood Hits	23
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

AP3B2_HUMAN
θ value	0.365318 (rank : 16)	NC score	0.059709 (rank : 16)
Query Neighborhood Hits	87	Target Neighborhood Hits	246	Shared Neighborhood Hits	12
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

JHD1B_MOUSE
θ value	0.365318 (rank : 17)	NC score	0.041071 (rank : 34)
Query Neighborhood Hits	87	Target Neighborhood Hits	214	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

NEST_HUMAN
θ value	0.62314 (rank : 18)	NC score	0.040353 (rank : 36)
Query Neighborhood Hits	87	Target Neighborhood Hits	1305	Shared Neighborhood Hits	28
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

DSPP_MOUSE
θ value	0.813845 (rank : 19)	NC score	0.076378 (rank : 8)
Query Neighborhood Hits	87	Target Neighborhood Hits	491	Shared Neighborhood Hits	21
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

NFH_MOUSE
θ value	0.813845 (rank : 20)	NC score	0.047513 (rank : 27)
Query Neighborhood Hits	87	Target Neighborhood Hits	2247	Shared Neighborhood Hits	50
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PCLO_MOUSE
θ value	0.813845 (rank : 21)	NC score	0.042918 (rank : 32)
Query Neighborhood Hits	87	Target Neighborhood Hits	2275	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PTN13_HUMAN
θ value	0.813845 (rank : 22)	NC score	0.022111 (rank : 62)
Query Neighborhood Hits	87	Target Neighborhood Hits	471	Shared Neighborhood Hits	13
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

TCOF_MOUSE
θ value	0.813845 (rank : 23)	NC score	0.080348 (rank : 6)
Query Neighborhood Hits	87	Target Neighborhood Hits	471	Shared Neighborhood Hits	27
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

ARI1B_HUMAN
θ value	1.06291 (rank : 24)	NC score	0.035514 (rank : 39)
Query Neighborhood Hits	87	Target Neighborhood Hits	567	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

NACAM_MOUSE
θ value	1.06291 (rank : 25)	NC score	0.054270 (rank : 22)
Query Neighborhood Hits	87	Target Neighborhood Hits	1866	Shared Neighborhood Hits	48
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

WNK1_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.012658 (rank : 75)
Query Neighborhood Hits	87	Target Neighborhood Hits	1158	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

AP3B1_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.047245 (rank : 28)
Query Neighborhood Hits	87	Target Neighborhood Hits	283	Shared Neighborhood Hits	16
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

K0240_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.033746 (rank : 41)
Query Neighborhood Hits	87	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	Q6AI39, Q5TFZ3, Q92514	Gene names	KIAA0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

MDC1_MOUSE
θ value	1.38821 (rank : 29)	NC score	0.057834 (rank : 17)
Query Neighborhood Hits	87	Target Neighborhood Hits	998	Shared Neighborhood Hits	38
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MKL2_MOUSE
θ value	1.38821 (rank : 30)	NC score	0.031715 (rank : 45)
Query Neighborhood Hits	87	Target Neighborhood Hits	269	Shared Neighborhood Hits	14
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

CIC_MOUSE
θ value	1.81305 (rank : 31)	NC score	0.033624 (rank : 42)
Query Neighborhood Hits	87	Target Neighborhood Hits	742	Shared Neighborhood Hits	18
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CRTC1_MOUSE
θ value	1.81305 (rank : 32)	NC score	0.054575 (rank : 21)
Query Neighborhood Hits	87	Target Neighborhood Hits	230	Shared Neighborhood Hits	14
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

K1219_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.040784 (rank : 35)
Query Neighborhood Hits	87	Target Neighborhood Hits	85	Shared Neighborhood Hits	6
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

PALM_MOUSE
θ value	1.81305 (rank : 34)	NC score	0.057660 (rank : 18)
Query Neighborhood Hits	87	Target Neighborhood Hits	228	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

ANLN_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.035704 (rank : 38)
Query Neighborhood Hits	87	Target Neighborhood Hits	222	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

CJ055_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.054938 (rank : 20)
Query Neighborhood Hits	87	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SWW7, Q8NAK4	Gene names	C10orf55
Domain Architecture	No domain graphic available
Description	Protein C10orf55.

IPR1_MOUSE
θ value	2.36792 (rank : 37)	NC score	0.044620 (rank : 31)
Query Neighborhood Hits	87	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BVK9, Q3UCV7, Q80V00	Gene names	Ipr1, Ifi75
Domain Architecture	No domain graphic available
Description	Intracellular pathogen resistance protein 1.

JIP3_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.031378 (rank : 46)
Query Neighborhood Hits	87	Target Neighborhood Hits	1039	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

NCOA1_MOUSE
θ value	2.36792 (rank : 39)	NC score	0.022175 (rank : 61)
Query Neighborhood Hits	87	Target Neighborhood Hits	196	Shared Neighborhood Hits	11
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

SI1L1_MOUSE
θ value	2.36792 (rank : 40)	NC score	0.023795 (rank : 56)
Query Neighborhood Hits	87	Target Neighborhood Hits	189	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

TARA_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.056684 (rank : 19)
Query Neighborhood Hits	87	Target Neighborhood Hits	1626	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ABL1_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.003358 (rank : 87)
Query Neighborhood Hits	87	Target Neighborhood Hits	1220	Shared Neighborhood Hits	15
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ACD_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.047566 (rank : 26)
Query Neighborhood Hits	87	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

MAP1B_MOUSE
θ value	3.0926 (rank : 44)	NC score	0.053379 (rank : 23)
Query Neighborhood Hits	87	Target Neighborhood Hits	977	Shared Neighborhood Hits	44
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MYPT1_HUMAN
θ value	3.0926 (rank : 45)	NC score	0.017652 (rank : 67)
Query Neighborhood Hits	87	Target Neighborhood Hits	723	Shared Neighborhood Hits	15
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

SMG1_MOUSE
θ value	3.0926 (rank : 46)	NC score	0.024049 (rank : 55)
Query Neighborhood Hits	87	Target Neighborhood Hits	212	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

TRAK1_HUMAN
θ value	3.0926 (rank : 47)	NC score	0.026199 (rank : 53)
Query Neighborhood Hits	87	Target Neighborhood Hits	660	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

AP3B1_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.046711 (rank : 29)
Query Neighborhood Hits	87	Target Neighborhood Hits	302	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

CAC1G_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.015949 (rank : 69)
Query Neighborhood Hits	87	Target Neighborhood Hits	587	Shared Neighborhood Hits	15
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

HIP1R_MOUSE
θ value	4.03905 (rank : 50)	NC score	0.024909 (rank : 54)
Query Neighborhood Hits	87	Target Neighborhood Hits	959	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

SLAF6_HUMAN
θ value	4.03905 (rank : 51)	NC score	0.030324 (rank : 49)
Query Neighborhood Hits	87	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q96DU3, Q5TAT3, Q96DV0	Gene names	SLAMF6, KALI
Domain Architecture	No domain graphic available
Description	SLAM family member 6 precursor (NK-T-B-antigen) (NTB-A) (Activating NK receptor).

TRPS1_MOUSE
θ value	4.03905 (rank : 52)	NC score	0.030404 (rank : 48)
Query Neighborhood Hits	87	Target Neighborhood Hits	609	Shared Neighborhood Hits	10
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

ZFA_MOUSE
θ value	4.03905 (rank : 53)	NC score	0.000391 (rank : 88)
Query Neighborhood Hits	87	Target Neighborhood Hits	746	Shared Neighborhood Hits	3
SwissProt Accessions	P23607	Gene names	Zfa
Domain Architecture
Description	Zinc finger autosomal protein.

ESPL1_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.018629 (rank : 66)
Query Neighborhood Hits	87	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

HIF1A_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.011837 (rank : 76)
Query Neighborhood Hits	87	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

MAGAB_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.014185 (rank : 72)
Query Neighborhood Hits	87	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P43364, Q5ETU4, Q6ZRZ5	Gene names	MAGEA11, MAGE11
Domain Architecture
Description	Melanoma-associated antigen 11 (MAGE-11 antigen).

MAML1_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.022835 (rank : 59)
Query Neighborhood Hits	87	Target Neighborhood Hits	228	Shared Neighborhood Hits	11
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MAP1A_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.042650 (rank : 33)
Query Neighborhood Hits	87	Target Neighborhood Hits	1626	Shared Neighborhood Hits	38
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

ANK3_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.011823 (rank : 77)
Query Neighborhood Hits	87	Target Neighborhood Hits	853	Shared Neighborhood Hits	28
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

APC_MOUSE
θ value	6.88961 (rank : 60)	NC score	0.044734 (rank : 30)
Query Neighborhood Hits	87	Target Neighborhood Hits	441	Shared Neighborhood Hits	23
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

IF4B_MOUSE
θ value	6.88961 (rank : 61)	NC score	0.026556 (rank : 52)
Query Neighborhood Hits	87	Target Neighborhood Hits	368	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

MAGB6_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.022403 (rank : 60)
Query Neighborhood Hits	87	Target Neighborhood Hits	184	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N7X4, Q6GS19, Q9H219	Gene names	MAGEB6
Domain Architecture
Description	Melanoma-associated antigen B6 (MAGE-B6 antigen).

MUCDL_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.015470 (rank : 70)
Query Neighborhood Hits	87	Target Neighborhood Hits	777	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

PCOC1_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.011589 (rank : 78)
Query Neighborhood Hits	87	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PGCB_MOUSE
θ value	6.88961 (rank : 65)	NC score	0.008277 (rank : 85)
Query Neighborhood Hits	87	Target Neighborhood Hits	459	Shared Neighborhood Hits	10
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PKDRE_MOUSE
θ value	6.88961 (rank : 66)	NC score	0.013355 (rank : 74)
Query Neighborhood Hits	87	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

RL1D1_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.053232 (rank : 24)
Query Neighborhood Hits	87	Target Neighborhood Hits	180	Shared Neighborhood Hits	19
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

SDPR_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.029303 (rank : 50)
Query Neighborhood Hits	87	Target Neighborhood Hits	337	Shared Neighborhood Hits	16
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

SETD2_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.033283 (rank : 43)
Query Neighborhood Hits	87	Target Neighborhood Hits	412	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SMG1_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.021110 (rank : 63)
Query Neighborhood Hits	87	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

TITIN_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.011334 (rank : 79)
Query Neighborhood Hits	87	Target Neighborhood Hits	2923	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

AHI1_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.008879 (rank : 82)
Query Neighborhood Hits	87	Target Neighborhood Hits	537	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

APC_HUMAN
θ value	8.99809 (rank : 73)	NC score	0.034758 (rank : 40)
Query Neighborhood Hits	87	Target Neighborhood Hits	603	Shared Neighborhood Hits	26
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

BPTF_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.027647 (rank : 51)
Query Neighborhood Hits	87	Target Neighborhood Hits	786	Shared Neighborhood Hits	27
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CX033_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.016972 (rank : 68)
Query Neighborhood Hits	87	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UXV4, Q5H9D1	Gene names	CXorf33
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf33 precursor.

DDX23_HUMAN
θ value	8.99809 (rank : 76)	NC score	0.010542 (rank : 80)
Query Neighborhood Hits	87	Target Neighborhood Hits	486	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

IF4B_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.033102 (rank : 44)
Query Neighborhood Hits	87	Target Neighborhood Hits	417	Shared Neighborhood Hits	19
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

MLL2_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.019390 (rank : 65)
Query Neighborhood Hits	87	Target Neighborhood Hits	1788	Shared Neighborhood Hits	35
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYPT1_MOUSE
θ value	8.99809 (rank : 79)	NC score	0.014172 (rank : 73)
Query Neighborhood Hits	87	Target Neighborhood Hits	539	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

PRG4_MOUSE
θ value	8.99809 (rank : 80)	NC score	0.030954 (rank : 47)
Query Neighborhood Hits	87	Target Neighborhood Hits	624	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

PRP40_MOUSE
θ value	8.99809 (rank : 81)	NC score	0.023229 (rank : 58)
Query Neighborhood Hits	87	Target Neighborhood Hits	447	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

RAE1_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.010235 (rank : 81)
Query Neighborhood Hits	87	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	P24386, O43732	Gene names	CHM, REP1, TCD
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 1 (Rab escort protein 1) (REP-1) (Choroideraemia protein) (TCD protein).

TAF6L_MOUSE
θ value	8.99809 (rank : 83)	NC score	0.020091 (rank : 64)
Query Neighborhood Hits	87	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

TIF1B_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.007775 (rank : 86)
Query Neighborhood Hits	87	Target Neighborhood Hits	312	Shared Neighborhood Hits	5
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TRA2B_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.008571 (rank : 83)
Query Neighborhood Hits	87	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	P62995, O15449, Q15815, Q64283	Gene names	SFRS10, TRA2B
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich-splicing factor 10 (Transformer-2-beta) (HTRA2- beta) (Transformer 2 protein homolog).

TRA2B_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.008571 (rank : 84)
Query Neighborhood Hits	87	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	P62996, O15449, Q15815, Q64283	Gene names	Sfrs10, Silg41, Tra2b
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich-splicing factor 10 (Transformer-2-beta) (HTRA2- beta) (Transformer 2 protein homolog) (Silica-induced gene 41 protein) (SIG-41).

ZAN_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.014298 (rank : 71)
Query Neighborhood Hits	87	Target Neighborhood Hits	679	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

CUTL2_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.050905 (rank : 25)
Query Neighborhood Hits	87	Target Neighborhood Hits	771	Shared Neighborhood Hits	15
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

Hits sorted by NC score

PACS1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	87	Target Neighborhood Hits	87	Shared Neighborhood Hits	87
SwissProt Accessions	Q8K212, Q6P5H8	Gene names	Pacs1
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

PACS1_HUMAN
NC score	0.988326 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	87	Target Neighborhood Hits	82	Shared Neighborhood Hits	55
SwissProt Accessions	Q6VY07, Q6PJY6, Q6PKB6, Q7Z590, Q7Z5W4, Q8N8K6, Q96MW0, Q9NW92, Q9ULP5	Gene names	PACS1, KIAA1175
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

DSPP_HUMAN
NC score	0.115728 (rank : 3)	θ value	0.00228821 (rank : 3)
Query Neighborhood Hits	87	Target Neighborhood Hits	645	Shared Neighborhood Hits	26
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

AFF4_HUMAN
NC score	0.111413 (rank : 4)	θ value	0.0148317 (rank : 7)
Query Neighborhood Hits	87	Target Neighborhood Hits	611	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

AFF4_MOUSE
NC score	0.100714 (rank : 5)	θ value	0.163984 (rank : 8)
Query Neighborhood Hits	87	Target Neighborhood Hits	581	Shared Neighborhood Hits	33
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

TCOF_MOUSE
NC score	0.080348 (rank : 6)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	87	Target Neighborhood Hits	471	Shared Neighborhood Hits	27
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TP53B_MOUSE
NC score	0.080327 (rank : 7)	θ value	0.279714 (rank : 15)
Query Neighborhood Hits	87	Target Neighborhood Hits	644	Shared Neighborhood Hits	23
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

DSPP_MOUSE
NC score	0.076378 (rank : 8)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	87	Target Neighborhood Hits	491	Shared Neighborhood Hits	21
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

GP158_HUMAN
NC score	0.075833 (rank : 9)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	87	Target Neighborhood Hits	221	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

CASP_MOUSE
NC score	0.073910 (rank : 10)	θ value	0.00869519 (rank : 5)
Query Neighborhood Hits	87	Target Neighborhood Hits	1152	Shared Neighborhood Hits	23
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_HUMAN
NC score	0.072722 (rank : 11)	θ value	0.0113563 (rank : 6)
Query Neighborhood Hits	87	Target Neighborhood Hits	1131	Shared Neighborhood Hits	22
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

RBBP6_HUMAN
NC score	0.069170 (rank : 12)	θ value	0.21417 (rank : 11)
Query Neighborhood Hits	87	Target Neighborhood Hits	1135	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

CUTL1_MOUSE
NC score	0.067894 (rank : 13)	θ value	0.163984 (rank : 10)
Query Neighborhood Hits	87	Target Neighborhood Hits	1620	Shared Neighborhood Hits	33
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CUTL1_HUMAN
NC score	0.066026 (rank : 14)	θ value	0.163984 (rank : 9)
Query Neighborhood Hits	87	Target Neighborhood Hits	1574	Shared Neighborhood Hits	30
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

NFH_HUMAN
NC score	0.059725 (rank : 15)	θ value	0.00509761 (rank : 4)
Query Neighborhood Hits	87	Target Neighborhood Hits	1242	Shared Neighborhood Hits	41
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

AP3B2_HUMAN
NC score	0.059709 (rank : 16)	θ value	0.365318 (rank : 16)
Query Neighborhood Hits	87	Target Neighborhood Hits	246	Shared Neighborhood Hits	12
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

MDC1_MOUSE
NC score	0.057834 (rank : 17)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	87	Target Neighborhood Hits	998	Shared Neighborhood Hits	38
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PALM_MOUSE
NC score	0.057660 (rank : 18)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	87	Target Neighborhood Hits	228	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z0P4, Q9Z0P3	Gene names	Palm
Domain Architecture
Description	Paralemmin.

TARA_HUMAN
NC score	0.056684 (rank : 19)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	87	Target Neighborhood Hits	1626	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CJ055_HUMAN
NC score	0.054938 (rank : 20)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	87	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	Q5SWW7, Q8NAK4	Gene names	C10orf55
Domain Architecture	No domain graphic available
Description	Protein C10orf55.

CRTC1_MOUSE
NC score	0.054575 (rank : 21)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	87	Target Neighborhood Hits	230	Shared Neighborhood Hits	14
SwissProt Accessions	Q68ED7, Q6ZQ85	Gene names	Crtc1, Kiaa0616, Mect1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1 homolog).

NACAM_MOUSE
NC score	0.054270 (rank : 22)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	87	Target Neighborhood Hits	1866	Shared Neighborhood Hits	48
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

MAP1B_MOUSE
NC score	0.053379 (rank : 23)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	87	Target Neighborhood Hits	977	Shared Neighborhood Hits	44
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

RL1D1_HUMAN
NC score	0.053232 (rank : 24)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	87	Target Neighborhood Hits	180	Shared Neighborhood Hits	19
SwissProt Accessions	O76021, Q6PL22, Q8IWS7, Q8WUZ1, Q9HDA9, Q9Y3Z9	Gene names	RSL1D1, CATX11, CSIG, PBK1
Domain Architecture	No domain graphic available
Description	Ribosomal L1 domain-containing protein 1 (Cellular senescence- inhibited gene protein) (Protein PBK1) (CATX-11).

CUTL2_MOUSE
NC score	0.050905 (rank : 25)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	87	Target Neighborhood Hits	771	Shared Neighborhood Hits	15
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

ACD_HUMAN
NC score	0.047566 (rank : 26)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	87	Target Neighborhood Hits	143	Shared Neighborhood Hits	7
SwissProt Accessions	Q96AP0, Q562H5, Q9H8F9	Gene names	ACD, PIP1, PTOP
Domain Architecture	No domain graphic available
Description	Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein).

NFH_MOUSE
NC score	0.047513 (rank : 27)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	87	Target Neighborhood Hits	2247	Shared Neighborhood Hits	50
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

AP3B1_HUMAN
NC score	0.047245 (rank : 28)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	87	Target Neighborhood Hits	283	Shared Neighborhood Hits	16
SwissProt Accessions	O00203, O00580, Q7Z393, Q9HD66	Gene names	AP3B1, ADTB3A
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

AP3B1_MOUSE
NC score	0.046711 (rank : 29)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	87	Target Neighborhood Hits	302	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1T1, Q91YR4	Gene names	Ap3b1
Domain Architecture
Description	AP-3 complex subunit beta-1 (Adapter-related protein complex 3 beta-1 subunit) (Beta3A-adaptin) (Adaptor protein complex AP-3 beta-1 subunit) (Clathrin assembly protein complex 3 beta-1 large chain).

APC_MOUSE
NC score	0.044734 (rank : 30)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	87	Target Neighborhood Hits	441	Shared Neighborhood Hits	23
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

IPR1_MOUSE
NC score	0.044620 (rank : 31)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	87	Target Neighborhood Hits	65	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BVK9, Q3UCV7, Q80V00	Gene names	Ipr1, Ifi75
Domain Architecture	No domain graphic available
Description	Intracellular pathogen resistance protein 1.

PCLO_MOUSE
NC score	0.042918 (rank : 32)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	87	Target Neighborhood Hits	2275	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

MAP1A_HUMAN
NC score	0.042650 (rank : 33)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	87	Target Neighborhood Hits	1626	Shared Neighborhood Hits	38
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

JHD1B_MOUSE
NC score	0.041071 (rank : 34)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	87	Target Neighborhood Hits	214	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P1G2, Q3V396, Q6PFD0, Q6ZPE8, Q9CSF7, Q9QZN6	Gene names	Fbxl10, Fbl10, Jhdm1b, Kiaa3014
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 1B (EC 1.14.11.-) (F-box/LRR-repeat protein 10) (F-box and leucine-rich repeat protein 10) (F-box protein FBL10).

K1219_HUMAN
NC score	0.040784 (rank : 35)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	87	Target Neighborhood Hits	85	Shared Neighborhood Hits	6
SwissProt Accessions	Q86X10, Q5TG31, Q8N3D1, Q8WWC0, Q9H3X8, Q9UJR1, Q9ULK1, Q9Y3G9	Gene names	KIAA1219
Domain Architecture	No domain graphic available
Description	Protein KIAA1219.

NEST_HUMAN
NC score	0.040353 (rank : 36)	θ value	0.62314 (rank : 18)
Query Neighborhood Hits	87	Target Neighborhood Hits	1305	Shared Neighborhood Hits	28
SwissProt Accessions	P48681, O00552	Gene names	NES
Domain Architecture
Description	Nestin.

TBX21_MOUSE
NC score	0.035794 (rank : 37)	θ value	0.279714 (rank : 14)
Query Neighborhood Hits	87	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JKD8, Q9R0A6	Gene names	Tbx21, Tbet, Tblym
Domain Architecture	No domain graphic available
Description	T-box transcription factor TBX21 (T-box protein 21) (Transcription factor TBLYM) (T-cell-specific T-box transcription factor T-bet).

ANLN_HUMAN
NC score	0.035704 (rank : 38)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	87	Target Neighborhood Hits	222	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

ARI1B_HUMAN
NC score	0.035514 (rank : 39)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	87	Target Neighborhood Hits	567	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NFD5, Q5JRD1, Q5VYC4, Q8IZY8, Q8TEV0, Q8TF02, Q99491, Q9ULI5	Gene names	ARID1B, DAN15, KIAA1235, OSA2
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 1B (ARID domain- containing protein 1B) (Osa homolog 2) (hOsa2) (p250R) (BRG1-binding protein hELD/OSA1) (BRG1-associated factor 250b) (BAF250B).

APC_HUMAN
NC score	0.034758 (rank : 40)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	87	Target Neighborhood Hits	603	Shared Neighborhood Hits	26
SwissProt Accessions	P25054, Q15162, Q15163, Q93042	Gene names	APC, DP2.5
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC).

K0240_HUMAN
NC score	0.033746 (rank : 41)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	87	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	Q6AI39, Q5TFZ3, Q92514	Gene names	KIAA0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

CIC_MOUSE
NC score	0.033624 (rank : 42)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	87	Target Neighborhood Hits	742	Shared Neighborhood Hits	18
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

SETD2_HUMAN
NC score	0.033283 (rank : 43)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	87	Target Neighborhood Hits	412	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

IF4B_HUMAN
NC score	0.033102 (rank : 44)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	87	Target Neighborhood Hits	417	Shared Neighborhood Hits	19
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

MKL2_MOUSE
NC score	0.031715 (rank : 45)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	87	Target Neighborhood Hits	269	Shared Neighborhood Hits	14
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

JIP3_HUMAN
NC score	0.031378 (rank : 46)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	87	Target Neighborhood Hits	1039	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

PRG4_MOUSE
NC score	0.030954 (rank : 47)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	87	Target Neighborhood Hits	624	Shared Neighborhood Hits	33
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

TRPS1_MOUSE
NC score	0.030404 (rank : 48)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	87	Target Neighborhood Hits	609	Shared Neighborhood Hits	10
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

SLAF6_HUMAN
NC score	0.030324 (rank : 49)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	87	Target Neighborhood Hits	62	Shared Neighborhood Hits	4
SwissProt Accessions	Q96DU3, Q5TAT3, Q96DV0	Gene names	SLAMF6, KALI
Domain Architecture	No domain graphic available
Description	SLAM family member 6 precursor (NK-T-B-antigen) (NTB-A) (Activating NK receptor).

SDPR_HUMAN
NC score	0.029303 (rank : 50)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	87	Target Neighborhood Hits	337	Shared Neighborhood Hits	16
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

BPTF_HUMAN
NC score	0.027647 (rank : 51)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	87	Target Neighborhood Hits	786	Shared Neighborhood Hits	27
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

IF4B_MOUSE
NC score	0.026556 (rank : 52)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	87	Target Neighborhood Hits	368	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

TRAK1_HUMAN
NC score	0.026199 (rank : 53)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	87	Target Neighborhood Hits	660	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

HIP1R_MOUSE
NC score	0.024909 (rank : 54)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	87	Target Neighborhood Hits	959	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

SMG1_MOUSE
NC score	0.024049 (rank : 55)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	87	Target Neighborhood Hits	212	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BKX6, Q5DU42, Q6ZQC0, Q8BLU4, Q8BWJ5, Q8BXD3	Gene names	Smg1, Kiaa0421
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1).

SI1L1_MOUSE
NC score	0.023795 (rank : 56)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	87	Target Neighborhood Hits	189	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C0T5, Q6PDI8, Q80U02, Q8C026	Gene names	Sipa1l1, Kiaa0440
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 1.

FOXE2_HUMAN
NC score	0.023652 (rank : 57)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	87	Target Neighborhood Hits	236	Shared Neighborhood Hits	7
SwissProt Accessions	Q99526	Gene names	FOXE2
Domain Architecture
Description	Forkhead box protein E2 (HNF-3/fork head-like protein 5) (HFKL5) (HFKH4).

PRP40_MOUSE
NC score	0.023229 (rank : 58)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	87	Target Neighborhood Hits	447	Shared Neighborhood Hits	17
SwissProt Accessions	Q9R1C7, Q61049, Q8BQ76, Q8BRW4, Q8C2U1	Gene names	Prpf40a, Fbp11, Fnbp3
Domain Architecture
Description	Pre-mRNA-processing factor 40 homolog A (Formin-binding protein 3) (Formin-binding protein 11) (FBP-11).

MAML1_HUMAN
NC score	0.022835 (rank : 59)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	87	Target Neighborhood Hits	228	Shared Neighborhood Hits	11
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

MAGB6_HUMAN
NC score	0.022403 (rank : 60)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	87	Target Neighborhood Hits	184	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N7X4, Q6GS19, Q9H219	Gene names	MAGEB6
Domain Architecture
Description	Melanoma-associated antigen B6 (MAGE-B6 antigen).

NCOA1_MOUSE
NC score	0.022175 (rank : 61)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	87	Target Neighborhood Hits	196	Shared Neighborhood Hits	11
SwissProt Accessions	P70365, P70366, Q61202, Q8CBI9	Gene names	Ncoa1, Src1
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 1 (EC 2.3.1.48) (NCoA-1) (Steroid receptor coactivator 1) (SRC-1) (Nuclear receptor coactivator protein 1) (mNRC-1).

PTN13_HUMAN
NC score	0.022111 (rank : 62)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	87	Target Neighborhood Hits	471	Shared Neighborhood Hits	13
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

SMG1_HUMAN
NC score	0.021110 (rank : 63)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	87	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

TAF6L_MOUSE
NC score	0.020091 (rank : 64)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	87	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R2K4, Q8C5T2	Gene names	Taf6l, Paf65a
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

MLL2_HUMAN
NC score	0.019390 (rank : 65)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	87	Target Neighborhood Hits	1788	Shared Neighborhood Hits	35
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ESPL1_HUMAN
NC score	0.018629 (rank : 66)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	87	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

MYPT1_HUMAN
NC score	0.017652 (rank : 67)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	87	Target Neighborhood Hits	723	Shared Neighborhood Hits	15
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

CX033_HUMAN
NC score	0.016972 (rank : 68)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	87	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q6UXV4, Q5H9D1	Gene names	CXorf33
Domain Architecture	No domain graphic available
Description	Uncharacterized protein CXorf33 precursor.

CAC1G_HUMAN
NC score	0.015949 (rank : 69)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	87	Target Neighborhood Hits	587	Shared Neighborhood Hits	15
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

MUCDL_HUMAN
NC score	0.015470 (rank : 70)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	87	Target Neighborhood Hits	777	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

ZAN_HUMAN
NC score	0.014298 (rank : 71)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	87	Target Neighborhood Hits	679	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

MAGAB_HUMAN
NC score	0.014185 (rank : 72)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	87	Target Neighborhood Hits	51	Shared Neighborhood Hits	4
SwissProt Accessions	P43364, Q5ETU4, Q6ZRZ5	Gene names	MAGEA11, MAGE11
Domain Architecture
Description	Melanoma-associated antigen 11 (MAGE-11 antigen).

MYPT1_MOUSE
NC score	0.014172 (rank : 73)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	87	Target Neighborhood Hits	539	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DBR7, Q8CBV2, Q99NB6	Gene names	Ppp1r12a, Mypt1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1).

PKDRE_MOUSE
NC score	0.013355 (rank : 74)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	87	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

WNK1_HUMAN
NC score	0.012658 (rank : 75)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	87	Target Neighborhood Hits	1158	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

HIF1A_HUMAN
NC score	0.011837 (rank : 76)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	87	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

ANK3_HUMAN
NC score	0.011823 (rank : 77)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	87	Target Neighborhood Hits	853	Shared Neighborhood Hits	28
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

PCOC1_HUMAN
NC score	0.011589 (rank : 78)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	87	Target Neighborhood Hits	146	Shared Neighborhood Hits	7
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

TITIN_HUMAN
NC score	0.011334 (rank : 79)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	87	Target Neighborhood Hits	2923	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

DDX23_HUMAN
NC score	0.010542 (rank : 80)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	87	Target Neighborhood Hits	486	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BUQ8, O43188	Gene names	DDX23
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX23 (EC 3.6.1.-) (DEAD box protein 23) (100 kDa U5 snRNP-specific protein) (U5-100kD) (PRP28 homolog).

RAE1_HUMAN
NC score	0.010235 (rank : 81)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	87	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	P24386, O43732	Gene names	CHM, REP1, TCD
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 1 (Rab escort protein 1) (REP-1) (Choroideraemia protein) (TCD protein).

AHI1_HUMAN
NC score	0.008879 (rank : 82)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	87	Target Neighborhood Hits	537	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N157, Q504T3, Q5TCP9, Q6P098, Q6PIT6, Q8NDX0, Q9H0H2	Gene names	AHI1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein homolog) (AHI-1).

TRA2B_HUMAN
NC score	0.008571 (rank : 83)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	87	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	P62995, O15449, Q15815, Q64283	Gene names	SFRS10, TRA2B
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich-splicing factor 10 (Transformer-2-beta) (HTRA2- beta) (Transformer 2 protein homolog).

TRA2B_MOUSE
NC score	0.008571 (rank : 84)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	87	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	P62996, O15449, Q15815, Q64283	Gene names	Sfrs10, Silg41, Tra2b
Domain Architecture	No domain graphic available
Description	Arginine/serine-rich-splicing factor 10 (Transformer-2-beta) (HTRA2- beta) (Transformer 2 protein homolog) (Silica-induced gene 41 protein) (SIG-41).

PGCB_MOUSE
NC score	0.008277 (rank : 85)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	87	Target Neighborhood Hits	459	Shared Neighborhood Hits	10
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

TIF1B_HUMAN
NC score	0.007775 (rank : 86)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	87	Target Neighborhood Hits	312	Shared Neighborhood Hits	5
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

ABL1_HUMAN
NC score	0.003358 (rank : 87)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	87	Target Neighborhood Hits	1220	Shared Neighborhood Hits	15
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ZFA_MOUSE
NC score	0.000391 (rank : 88)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	87	Target Neighborhood Hits	746	Shared Neighborhood Hits	3
SwissProt Accessions	P23607	Gene names	Zfa
Domain Architecture
Description	Zinc finger autosomal protein.