Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : CDKN3_HUMAN

For an explanation of this page, click here

CDKN3_HUMAN
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CDKN3_HUMAN
θ value	2.00348e-116 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	27	Target Neighborhood Hits	27	Shared Neighborhood Hits	27
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

TP4A2_HUMAN
θ value	0.125558 (rank : 2)	NC score	0.228027 (rank : 2)
Query Neighborhood Hits	27	Target Neighborhood Hits	56	Shared Neighborhood Hits	12
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
θ value	0.125558 (rank : 3)	NC score	0.228027 (rank : 3)
Query Neighborhood Hits	27	Target Neighborhood Hits	56	Shared Neighborhood Hits	12
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

PTN5_MOUSE
θ value	0.163984 (rank : 4)	NC score	0.118177 (rank : 8)
Query Neighborhood Hits	27	Target Neighborhood Hits	85	Shared Neighborhood Hits	18
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN3_HUMAN
θ value	0.21417 (rank : 5)	NC score	0.083889 (rank : 23)
Query Neighborhood Hits	27	Target Neighborhood Hits	258	Shared Neighborhood Hits	18
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTN7_MOUSE
θ value	0.21417 (rank : 6)	NC score	0.116602 (rank : 11)
Query Neighborhood Hits	27	Target Neighborhood Hits	71	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

TP4A3_MOUSE
θ value	0.21417 (rank : 7)	NC score	0.220547 (rank : 4)
Query Neighborhood Hits	27	Target Neighborhood Hits	60	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

TP4A1_HUMAN
θ value	0.47712 (rank : 8)	NC score	0.218493 (rank : 5)
Query Neighborhood Hits	27	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
θ value	0.47712 (rank : 9)	NC score	0.218493 (rank : 6)
Query Neighborhood Hits	27	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

TP4A3_HUMAN
θ value	0.47712 (rank : 10)	NC score	0.214942 (rank : 7)
Query Neighborhood Hits	27	Target Neighborhood Hits	62	Shared Neighborhood Hits	12
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

PTPRT_HUMAN
θ value	0.62314 (rank : 11)	NC score	0.088711 (rank : 16)
Query Neighborhood Hits	27	Target Neighborhood Hits	217	Shared Neighborhood Hits	14
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
θ value	0.62314 (rank : 12)	NC score	0.088663 (rank : 17)
Query Neighborhood Hits	27	Target Neighborhood Hits	219	Shared Neighborhood Hits	14
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRR_HUMAN
θ value	0.813845 (rank : 13)	NC score	0.117139 (rank : 10)
Query Neighborhood Hits	27	Target Neighborhood Hits	77	Shared Neighborhood Hits	14
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTN7_HUMAN
θ value	1.06291 (rank : 14)	NC score	0.112290 (rank : 12)
Query Neighborhood Hits	27	Target Neighborhood Hits	75	Shared Neighborhood Hits	14
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTPRR_MOUSE
θ value	1.06291 (rank : 15)	NC score	0.117141 (rank : 9)
Query Neighborhood Hits	27	Target Neighborhood Hits	84	Shared Neighborhood Hits	16
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

CC14B_HUMAN
θ value	1.81305 (rank : 16)	NC score	0.096838 (rank : 14)
Query Neighborhood Hits	27	Target Neighborhood Hits	114	Shared Neighborhood Hits	21
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

PAPPA_MOUSE
θ value	4.03905 (rank : 17)	NC score	0.026744 (rank : 79)
Query Neighborhood Hits	27	Target Neighborhood Hits	153	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PTEN_HUMAN
θ value	4.03905 (rank : 18)	NC score	0.082179 (rank : 24)
Query Neighborhood Hits	27	Target Neighborhood Hits	72	Shared Neighborhood Hits	14
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
θ value	4.03905 (rank : 19)	NC score	0.082177 (rank : 25)
Query Neighborhood Hits	27	Target Neighborhood Hits	73	Shared Neighborhood Hits	14
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

PTN2_HUMAN
θ value	4.03905 (rank : 20)	NC score	0.085016 (rank : 19)
Query Neighborhood Hits	27	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTPRV_MOUSE
θ value	4.03905 (rank : 21)	NC score	0.088220 (rank : 18)
Query Neighborhood Hits	27	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTPRB_HUMAN
θ value	5.27518 (rank : 22)	NC score	0.088723 (rank : 15)
Query Neighborhood Hits	27	Target Neighborhood Hits	242	Shared Neighborhood Hits	23
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

DUS12_MOUSE
θ value	6.88961 (rank : 23)	NC score	0.020947 (rank : 80)
Query Neighborhood Hits	27	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D0T2, Q9EQD3	Gene names	Dusp12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity phosphatase T-DSP4) (Dual specificity phosphatase VH1).

UBP34_HUMAN
θ value	6.88961 (rank : 24)	NC score	0.028075 (rank : 78)
Query Neighborhood Hits	27	Target Neighborhood Hits	210	Shared Neighborhood Hits	3
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_MOUSE
θ value	6.88961 (rank : 25)	NC score	0.028210 (rank : 77)
Query Neighborhood Hits	27	Target Neighborhood Hits	189	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

ATM_HUMAN
θ value	8.99809 (rank : 26)	NC score	0.016465 (rank : 81)
Query Neighborhood Hits	27	Target Neighborhood Hits	78	Shared Neighborhood Hits	2
SwissProt Accessions	Q13315, O15429, Q12758, Q16551, Q93007, Q9NP02, Q9UCX7	Gene names	ATM
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T, mutated).

PTPRU_HUMAN
θ value	8.99809 (rank : 27)	NC score	0.080952 (rank : 27)
Query Neighborhood Hits	27	Target Neighborhood Hits	237	Shared Neighborhood Hits	16
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

CC14A_HUMAN
θ value	θ > 10 (rank : 28)	NC score	0.073477 (rank : 59)
Query Neighborhood Hits	27	Target Neighborhood Hits	133	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14A_MOUSE
θ value	θ > 10 (rank : 29)	NC score	0.072933 (rank : 60)
Query Neighborhood Hits	27	Target Neighborhood Hits	117	Shared Neighborhood Hits	20
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14B_MOUSE
θ value	θ > 10 (rank : 30)	NC score	0.081798 (rank : 26)
Query Neighborhood Hits	27	Target Neighborhood Hits	103	Shared Neighborhood Hits	20
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

CD45_HUMAN
θ value	θ > 10 (rank : 31)	NC score	0.076253 (rank : 47)
Query Neighborhood Hits	27	Target Neighborhood Hits	243	Shared Neighborhood Hits	16
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

CD45_MOUSE
θ value	θ > 10 (rank : 32)	NC score	0.076599 (rank : 44)
Query Neighborhood Hits	27	Target Neighborhood Hits	178	Shared Neighborhood Hits	15
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

DUS23_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.074615 (rank : 55)
Query Neighborhood Hits	27	Target Neighborhood Hits	98	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

DUS23_MOUSE
θ value	θ > 10 (rank : 34)	NC score	0.076176 (rank : 48)
Query Neighborhood Hits	27	Target Neighborhood Hits	94	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

PTN11_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.074491 (rank : 58)
Query Neighborhood Hits	27	Target Neighborhood Hits	227	Shared Neighborhood Hits	19
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

PTN11_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.074522 (rank : 57)
Query Neighborhood Hits	27	Target Neighborhood Hits	227	Shared Neighborhood Hits	19
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN12_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.084496 (rank : 20)
Query Neighborhood Hits	27	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTN12_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.084239 (rank : 22)
Query Neighborhood Hits	27	Target Neighborhood Hits	123	Shared Neighborhood Hits	20
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN13_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.058452 (rank : 75)
Query Neighborhood Hits	27	Target Neighborhood Hits	471	Shared Neighborhood Hits	19
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTN13_MOUSE
θ value	θ > 10 (rank : 40)	NC score	0.059638 (rank : 72)
Query Neighborhood Hits	27	Target Neighborhood Hits	426	Shared Neighborhood Hits	19
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTN14_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.063793 (rank : 67)
Query Neighborhood Hits	27	Target Neighborhood Hits	163	Shared Neighborhood Hits	17
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN14_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.061881 (rank : 68)
Query Neighborhood Hits	27	Target Neighborhood Hits	142	Shared Neighborhood Hits	15
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN18_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.076640 (rank : 43)
Query Neighborhood Hits	27	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

PTN18_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.080007 (rank : 28)
Query Neighborhood Hits	27	Target Neighborhood Hits	134	Shared Neighborhood Hits	17
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTN1_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.079332 (rank : 31)
Query Neighborhood Hits	27	Target Neighborhood Hits	84	Shared Neighborhood Hits	15
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTN1_MOUSE
θ value	θ > 10 (rank : 46)	NC score	0.079016 (rank : 33)
Query Neighborhood Hits	27	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN21_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.061472 (rank : 70)
Query Neighborhood Hits	27	Target Neighborhood Hits	143	Shared Neighborhood Hits	15
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTN21_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.061618 (rank : 69)
Query Neighborhood Hits	27	Target Neighborhood Hits	155	Shared Neighborhood Hits	16
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN22_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.077842 (rank : 38)
Query Neighborhood Hits	27	Target Neighborhood Hits	109	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTN22_MOUSE
θ value	θ > 10 (rank : 50)	NC score	0.076865 (rank : 41)
Query Neighborhood Hits	27	Target Neighborhood Hits	179	Shared Neighborhood Hits	16
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTN23_HUMAN
θ value	θ > 10 (rank : 51)	NC score	0.064754 (rank : 66)
Query Neighborhood Hits	27	Target Neighborhood Hits	646	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	θ > 10 (rank : 52)	NC score	0.065661 (rank : 65)
Query Neighborhood Hits	27	Target Neighborhood Hits	726	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN2_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.078318 (rank : 36)
Query Neighborhood Hits	27	Target Neighborhood Hits	107	Shared Neighborhood Hits	13
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTN4_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.069935 (rank : 61)
Query Neighborhood Hits	27	Target Neighborhood Hits	303	Shared Neighborhood Hits	19
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTN5_HUMAN
θ value	θ > 10 (rank : 55)	NC score	0.103850 (rank : 13)
Query Neighborhood Hits	27	Target Neighborhood Hits	80	Shared Neighborhood Hits	19
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTN6_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.075821 (rank : 52)
Query Neighborhood Hits	27	Target Neighborhood Hits	234	Shared Neighborhood Hits	17
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN6_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.075866 (rank : 51)
Query Neighborhood Hits	27	Target Neighborhood Hits	225	Shared Neighborhood Hits	19
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN9_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.075802 (rank : 53)
Query Neighborhood Hits	27	Target Neighborhood Hits	79	Shared Neighborhood Hits	13
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN9_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.075926 (rank : 50)
Query Neighborhood Hits	27	Target Neighborhood Hits	78	Shared Neighborhood Hits	13
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPR2_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.076531 (rank : 45)
Query Neighborhood Hits	27	Target Neighborhood Hits	103	Shared Neighborhood Hits	16
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPR2_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.076026 (rank : 49)
Query Neighborhood Hits	27	Target Neighborhood Hits	120	Shared Neighborhood Hits	16
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTPRA_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.076303 (rank : 46)
Query Neighborhood Hits	27	Target Neighborhood Hits	101	Shared Neighborhood Hits	17
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PTPRA_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.076701 (rank : 42)
Query Neighborhood Hits	27	Target Neighborhood Hits	93	Shared Neighborhood Hits	17
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRD_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.058739 (rank : 73)
Query Neighborhood Hits	27	Target Neighborhood Hits	485	Shared Neighborhood Hits	22
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRD_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.058065 (rank : 76)
Query Neighborhood Hits	27	Target Neighborhood Hits	491	Shared Neighborhood Hits	22
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRE_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.079268 (rank : 32)
Query Neighborhood Hits	27	Target Neighborhood Hits	92	Shared Neighborhood Hits	19
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRE_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.078887 (rank : 34)
Query Neighborhood Hits	27	Target Neighborhood Hits	86	Shared Neighborhood Hits	19
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRF_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.058518 (rank : 74)
Query Neighborhood Hits	27	Target Neighborhood Hits	489	Shared Neighborhood Hits	22
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTPRG_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.068456 (rank : 63)
Query Neighborhood Hits	27	Target Neighborhood Hits	231	Shared Neighborhood Hits	15
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.068525 (rank : 62)
Query Neighborhood Hits	27	Target Neighborhood Hits	260	Shared Neighborhood Hits	15
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRJ_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.079913 (rank : 30)
Query Neighborhood Hits	27	Target Neighborhood Hits	207	Shared Neighborhood Hits	18
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTPRJ_MOUSE
θ value	θ > 10 (rank : 72)	NC score	0.079968 (rank : 29)
Query Neighborhood Hits	27	Target Neighborhood Hits	188	Shared Neighborhood Hits	17
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRK_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.078533 (rank : 35)
Query Neighborhood Hits	27	Target Neighborhood Hits	228	Shared Neighborhood Hits	15
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRK_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.078210 (rank : 37)
Query Neighborhood Hits	27	Target Neighborhood Hits	223	Shared Neighborhood Hits	15
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTPRM_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.077035 (rank : 40)
Query Neighborhood Hits	27	Target Neighborhood Hits	244	Shared Neighborhood Hits	17
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.077350 (rank : 39)
Query Neighborhood Hits	27	Target Neighborhood Hits	238	Shared Neighborhood Hits	17
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRN_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.075221 (rank : 54)
Query Neighborhood Hits	27	Target Neighborhood Hits	156	Shared Neighborhood Hits	16
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

PTPRN_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.074597 (rank : 56)
Query Neighborhood Hits	27	Target Neighborhood Hits	240	Shared Neighborhood Hits	16
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTPRO_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.084384 (rank : 21)
Query Neighborhood Hits	27	Target Neighborhood Hits	139	Shared Neighborhood Hits	17
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTPRS_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.059930 (rank : 71)
Query Neighborhood Hits	27	Target Neighborhood Hits	472	Shared Neighborhood Hits	22
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTPRZ_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.067949 (rank : 64)
Query Neighborhood Hits	27	Target Neighborhood Hits	255	Shared Neighborhood Hits	13
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

Hits sorted by NC score

CDKN3_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.00348e-116 (rank : 1)
Query Neighborhood Hits	27	Target Neighborhood Hits	27	Shared Neighborhood Hits	27
SwissProt Accessions	Q16667, Q99585, Q9BPW7, Q9BY36, Q9C042, Q9C047, Q9C049, Q9C051, Q9C053	Gene names	CDKN3, CDI1, CIP2, KAP
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.48) (EC 3.1.3.16) (CDK2- associated dual-specificity phosphatase) (Kinase-associated phosphatase) (Cyclin-dependent kinase-interacting protein 2) (Cyclin- dependent kinase interactor 1).

TP4A2_HUMAN
NC score	0.228027 (rank : 2)	θ value	0.125558 (rank : 2)
Query Neighborhood Hits	27	Target Neighborhood Hits	56	Shared Neighborhood Hits	12
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
NC score	0.228027 (rank : 3)	θ value	0.125558 (rank : 3)
Query Neighborhood Hits	27	Target Neighborhood Hits	56	Shared Neighborhood Hits	12
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

TP4A3_MOUSE
NC score	0.220547 (rank : 4)	θ value	0.21417 (rank : 7)
Query Neighborhood Hits	27	Target Neighborhood Hits	60	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

TP4A1_HUMAN
NC score	0.218493 (rank : 5)	θ value	0.47712 (rank : 8)
Query Neighborhood Hits	27	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
NC score	0.218493 (rank : 6)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	27	Target Neighborhood Hits	68	Shared Neighborhood Hits	14
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

TP4A3_HUMAN
NC score	0.214942 (rank : 7)	θ value	0.47712 (rank : 10)
Query Neighborhood Hits	27	Target Neighborhood Hits	62	Shared Neighborhood Hits	12
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

PTN5_MOUSE
NC score	0.118177 (rank : 8)	θ value	0.163984 (rank : 4)
Query Neighborhood Hits	27	Target Neighborhood Hits	85	Shared Neighborhood Hits	18
SwissProt Accessions	P54830, Q64694	Gene names	Ptpn5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

PTPRR_MOUSE
NC score	0.117141 (rank : 9)	θ value	1.06291 (rank : 15)
Query Neighborhood Hits	27	Target Neighborhood Hits	84	Shared Neighborhood Hits	16
SwissProt Accessions	Q62132, Q64491, Q64492, Q9QUH9	Gene names	Ptprr, Ptp13
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine-phosphatase SL) (Phosphotyrosine phosphatase 13).

PTPRR_HUMAN
NC score	0.117139 (rank : 10)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	27	Target Neighborhood Hits	77	Shared Neighborhood Hits	14
SwissProt Accessions	Q15256, O00342, Q92682, Q9UE65	Gene names	PTPRR, ECPTP
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase R precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase PCPTP1) (NC-PTPCOM1) (Ch-1PTPase).

PTN7_MOUSE
NC score	0.116602 (rank : 11)	θ value	0.21417 (rank : 6)
Query Neighborhood Hits	27	Target Neighborhood Hits	71	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BUM3	Gene names	Ptpn7
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48).

PTN7_HUMAN
NC score	0.112290 (rank : 12)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	27	Target Neighborhood Hits	75	Shared Neighborhood Hits	14
SwissProt Accessions	P35236, Q9BV05	Gene names	PTPN7
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 7 (EC 3.1.3.48) (Protein-tyrosine phosphatase LC-PTP) (Hematopoietic protein-tyrosine phosphatase) (HEPTP).

PTN5_HUMAN
NC score	0.103850 (rank : 13)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	27	Target Neighborhood Hits	80	Shared Neighborhood Hits	19
SwissProt Accessions	P54829, Q8N2A1	Gene names	PTPN5
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Protein-tyrosine phosphatase striatum-enriched) (STEP) (Neural- specific protein-tyrosine phosphatase).

CC14B_HUMAN
NC score	0.096838 (rank : 14)	θ value	1.81305 (rank : 16)
Query Neighborhood Hits	27	Target Neighborhood Hits	114	Shared Neighborhood Hits	21
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

PTPRB_HUMAN
NC score	0.088723 (rank : 15)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	27	Target Neighborhood Hits	242	Shared Neighborhood Hits	23
SwissProt Accessions	P23467	Gene names	PTPRB, PTPB
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase beta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase beta) (R-PTP-beta).

PTPRT_HUMAN
NC score	0.088711 (rank : 16)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	27	Target Neighborhood Hits	217	Shared Neighborhood Hits	14
SwissProt Accessions	O14522, O43655, O75664, Q5W0X9, Q5W0Y1, Q9BR24, Q9BR28, Q9H0Y8, Q9NTL1, Q9NU72, Q9UBD2, Q9UJL7	Gene names	PTPRT, KIAA0283
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho).

PTPRT_MOUSE
NC score	0.088663 (rank : 17)	θ value	0.62314 (rank : 12)
Query Neighborhood Hits	27	Target Neighborhood Hits	219	Shared Neighborhood Hits	14
SwissProt Accessions	Q99M80, Q99M81, Q99M82, Q9JIZ1, Q9JIZ2, Q9JKC2, Q9JLP0	Gene names	Ptprt
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase T precursor (EC 3.1.3.48) (R-PTP-T) (RPTP-rho) (mRPTPrho) (RPTPmam4).

PTPRV_MOUSE
NC score	0.088220 (rank : 18)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	27	Target Neighborhood Hits	179	Shared Neighborhood Hits	17
SwissProt Accessions	P70289	Gene names	Ptprv, Esp
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase V precursor (EC 3.1.3.48) (Embryonic stem cell protein-tyrosine phosphatase) (ES cell phosphatase).

PTN2_HUMAN
NC score	0.085016 (rank : 19)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	27	Target Neighborhood Hits	92	Shared Neighborhood Hits	13
SwissProt Accessions	P17706, Q96HR2	Gene names	PTPN2, PTPT
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP).

PTN12_HUMAN
NC score	0.084496 (rank : 20)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	27	Target Neighborhood Hits	102	Shared Neighborhood Hits	21
SwissProt Accessions	Q05209, Q16130, Q59FD6, Q75MN8, Q86XU4	Gene names	PTPN12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase G1) (PTPG1).

PTPRO_HUMAN
NC score	0.084384 (rank : 21)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	27	Target Neighborhood Hits	139	Shared Neighborhood Hits	17
SwissProt Accessions	Q16827, Q13101	Gene names	PTPRO, GLEPP1, PTPU2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase O precursor (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTPase U2) (PTP-U2).

PTN12_MOUSE
NC score	0.084239 (rank : 22)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	27	Target Neighborhood Hits	123	Shared Neighborhood Hits	20
SwissProt Accessions	P35831	Gene names	Ptpn12
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (Protein-tyrosine phosphatase P19) (P19-PTP) (MPTP-PEST).

PTN3_HUMAN
NC score	0.083889 (rank : 23)	θ value	0.21417 (rank : 5)
Query Neighborhood Hits	27	Target Neighborhood Hits	258	Shared Neighborhood Hits	18
SwissProt Accessions	P26045	Gene names	PTPN3, PTPH1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1).

PTEN_HUMAN
NC score	0.082179 (rank : 24)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	27	Target Neighborhood Hits	72	Shared Neighborhood Hits	14
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
NC score	0.082177 (rank : 25)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	27	Target Neighborhood Hits	73	Shared Neighborhood Hits	14
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

CC14B_MOUSE
NC score	0.081798 (rank : 26)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	27	Target Neighborhood Hits	103	Shared Neighborhood Hits	20
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

PTPRU_HUMAN
NC score	0.080952 (rank : 27)	θ value	8.99809 (rank : 27)
Query Neighborhood Hits	27	Target Neighborhood Hits	237	Shared Neighborhood Hits	16
SwissProt Accessions	Q92729	Gene names	PTPRU, PCP2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase U precursor (EC 3.1.3.48) (R-PTP-U) (Protein-tyrosine phosphatase J) (PTP-J) (Pancreatic carcinoma phosphatase 2) (PCP-2).

PTN18_MOUSE
NC score	0.080007 (rank : 28)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	27	Target Neighborhood Hits	134	Shared Neighborhood Hits	17
SwissProt Accessions	Q61152, Q4JFH4, Q62404, Q922E3	Gene names	Ptpn18, Flp1, Ptpk1
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Fetal liver phosphatase 1) (FLP-1) (PTP-K1).

PTPRJ_MOUSE
NC score	0.079968 (rank : 29)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	27	Target Neighborhood Hits	188	Shared Neighborhood Hits	17
SwissProt Accessions	Q64455	Gene names	Ptprj, Byp, Scc1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP beta-like tyrosine phosphatase) (Protein-tyrosine phosphatase receptor type J) (Susceptibility to colon cancer 1).

PTPRJ_HUMAN
NC score	0.079913 (rank : 30)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	27	Target Neighborhood Hits	207	Shared Neighborhood Hits	18
SwissProt Accessions	Q12913, Q15255, Q8NHM2	Gene names	PTPRJ, DEP1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase eta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase eta) (R-PTP-eta) (HPTP eta) (Protein- tyrosine phosphatase receptor type J) (Density-enhanced phosphatase 1) (DEP-1) (CD148 antigen).

PTN1_HUMAN
NC score	0.079332 (rank : 31)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	27	Target Neighborhood Hits	84	Shared Neighborhood Hits	15
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

PTPRE_HUMAN
NC score	0.079268 (rank : 32)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	27	Target Neighborhood Hits	92	Shared Neighborhood Hits	19
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTN1_MOUSE
NC score	0.079016 (rank : 33)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	27	Target Neighborhood Hits	85	Shared Neighborhood Hits	13
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTPRE_MOUSE
NC score	0.078887 (rank : 34)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	27	Target Neighborhood Hits	86	Shared Neighborhood Hits	19
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRK_HUMAN
NC score	0.078533 (rank : 35)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	27	Target Neighborhood Hits	228	Shared Neighborhood Hits	15
SwissProt Accessions	Q15262, Q14763	Gene names	PTPRK, PTPK
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTN2_MOUSE
NC score	0.078318 (rank : 36)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	27	Target Neighborhood Hits	107	Shared Neighborhood Hits	13
SwissProt Accessions	Q06180, Q3V259, Q922E7	Gene names	Ptpn2, Ptpt
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-2) (MPTP).

PTPRK_MOUSE
NC score	0.078210 (rank : 37)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	27	Target Neighborhood Hits	223	Shared Neighborhood Hits	15
SwissProt Accessions	P35822	Gene names	Ptprk, Ptpk
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase kappa precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase kappa) (R-PTP-kappa).

PTN22_HUMAN
NC score	0.077842 (rank : 38)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	27	Target Neighborhood Hits	109	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2R2, O95063, O95064	Gene names	PTPN22, PTPN8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP) (Lymphoid phosphatase) (LyP).

PTPRM_MOUSE
NC score	0.077350 (rank : 39)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	27	Target Neighborhood Hits	238	Shared Neighborhood Hits	17
SwissProt Accessions	P28828	Gene names	Ptprm
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTPRM_HUMAN
NC score	0.077035 (rank : 40)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	27	Target Neighborhood Hits	244	Shared Neighborhood Hits	17
SwissProt Accessions	P28827	Gene names	PTPRM, PTPRL1
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase mu precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase mu) (R-PTP-mu).

PTN22_MOUSE
NC score	0.076865 (rank : 41)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	27	Target Neighborhood Hits	179	Shared Neighborhood Hits	16
SwissProt Accessions	P29352, Q7TMP9	Gene names	Ptpn22, Ptpn8
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 22 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP).

PTPRA_MOUSE
NC score	0.076701 (rank : 42)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	27	Target Neighborhood Hits	93	Shared Neighborhood Hits	17
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTN18_HUMAN
NC score	0.076640 (rank : 43)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	27	Target Neighborhood Hits	73	Shared Neighborhood Hits	12
SwissProt Accessions	Q99952	Gene names	PTPN18, BDP1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 18 (EC 3.1.3.48) (Brain-derived phosphatase).

CD45_MOUSE
NC score	0.076599 (rank : 44)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	27	Target Neighborhood Hits	178	Shared Neighborhood Hits	15
SwissProt Accessions	P06800, Q61812, Q61813, Q61814, Q61815, Q78EF1	Gene names	Ptprc, Ly-5
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (Lymphocyte common antigen Ly-5) (CD45 antigen) (T200).

PTPR2_HUMAN
NC score	0.076531 (rank : 45)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	27	Target Neighborhood Hits	103	Shared Neighborhood Hits	16
SwissProt Accessions	Q92932, Q8N4I5, Q92662	Gene names	PTPRN2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (Islet cell autoantigen-related protein) (ICAAR) (IAR) (Phogrin).

PTPRA_HUMAN
NC score	0.076303 (rank : 46)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	27	Target Neighborhood Hits	101	Shared Neighborhood Hits	17
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

CD45_HUMAN
NC score	0.076253 (rank : 47)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	27	Target Neighborhood Hits	243	Shared Neighborhood Hits	16
SwissProt Accessions	P08575, Q16614, Q9H0Y6	Gene names	PTPRC, CD45
Domain Architecture
Description	Leukocyte common antigen precursor (EC 3.1.3.48) (L-CA) (CD45 antigen) (T200).

DUS23_MOUSE
NC score	0.076176 (rank : 48)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	27	Target Neighborhood Hits	94	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

PTPR2_MOUSE
NC score	0.076026 (rank : 49)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	27	Target Neighborhood Hits	120	Shared Neighborhood Hits	16
SwissProt Accessions	P80560, O09134, P70328	Gene names	Ptprn2
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase N2 precursor (EC 3.1.3.48) (R-PTP-N2) (PTP IA-2beta) (Protein tyrosine phosphatase-NP) (PTP-NP).

PTN9_MOUSE
NC score	0.075926 (rank : 50)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	27	Target Neighborhood Hits	78	Shared Neighborhood Hits	13
SwissProt Accessions	O35239, Q7TSK0	Gene names	Ptpn9
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTN6_MOUSE
NC score	0.075866 (rank : 51)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	27	Target Neighborhood Hits	225	Shared Neighborhood Hits	19
SwissProt Accessions	P29351, O35128, Q63872, Q63873, Q63874, Q921G3, Q9QVA6, Q9QVA7, Q9QVA8, Q9R0V6	Gene names	Ptpn6, Hcp, Hcph, Ptp1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (70Z-SHP) (SH-PTP1) (SHP-1) (PTPTY-42).

PTN6_HUMAN
NC score	0.075821 (rank : 52)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	27	Target Neighborhood Hits	234	Shared Neighborhood Hits	17
SwissProt Accessions	P29350, Q969V8	Gene names	PTPN6, HCP, PTP1C
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1).

PTN9_HUMAN
NC score	0.075802 (rank : 53)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	27	Target Neighborhood Hits	79	Shared Neighborhood Hits	13
SwissProt Accessions	P43378	Gene names	PTPN9
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2).

PTPRN_HUMAN
NC score	0.075221 (rank : 54)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	27	Target Neighborhood Hits	156	Shared Neighborhood Hits	16
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

DUS23_HUMAN
NC score	0.074615 (rank : 55)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	27	Target Neighborhood Hits	98	Shared Neighborhood Hits	22
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

PTPRN_MOUSE
NC score	0.074597 (rank : 56)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	27	Target Neighborhood Hits	240	Shared Neighborhood Hits	16
SwissProt Accessions	Q60673, Q62129	Gene names	Ptprn, Ptp35
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2).

PTN11_MOUSE
NC score	0.074522 (rank : 57)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	27	Target Neighborhood Hits	227	Shared Neighborhood Hits	19
SwissProt Accessions	P35235, Q3TQ84, Q64509, Q6PCL5	Gene names	Ptpn11
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2).

PTN11_HUMAN
NC score	0.074491 (rank : 58)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	27	Target Neighborhood Hits	227	Shared Neighborhood Hits	19
SwissProt Accessions	Q06124, Q96HD7	Gene names	PTPN11, PTP2C, SHPTP2
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase 2C) (PTP-2C) (PTP-1D) (SH-PTP3) (SH- PTP2) (SHP-2) (Shp2).

CC14A_HUMAN
NC score	0.073477 (rank : 59)	θ value	θ > 10 (rank : 28)
Query Neighborhood Hits	27	Target Neighborhood Hits	133	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14A_MOUSE
NC score	0.072933 (rank : 60)	θ value	θ > 10 (rank : 29)
Query Neighborhood Hits	27	Target Neighborhood Hits	117	Shared Neighborhood Hits	20
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

PTN4_HUMAN
NC score	0.069935 (rank : 61)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	27	Target Neighborhood Hits	303	Shared Neighborhood Hits	19
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PTPRG_MOUSE
NC score	0.068525 (rank : 62)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	27	Target Neighborhood Hits	260	Shared Neighborhood Hits	15
SwissProt Accessions	Q05909	Gene names	Ptprg
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRG_HUMAN
NC score	0.068456 (rank : 63)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	27	Target Neighborhood Hits	231	Shared Neighborhood Hits	15
SwissProt Accessions	P23470, Q15623	Gene names	PTPRG
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase gamma precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase gamma) (R-PTP-gamma).

PTPRZ_HUMAN
NC score	0.067949 (rank : 64)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	27	Target Neighborhood Hits	255	Shared Neighborhood Hits	13
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

PTN23_MOUSE
NC score	0.065661 (rank : 65)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	27	Target Neighborhood Hits	726	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PTN23_HUMAN
NC score	0.064754 (rank : 66)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	27	Target Neighborhood Hits	646	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN14_HUMAN
NC score	0.063793 (rank : 67)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	27	Target Neighborhood Hits	163	Shared Neighborhood Hits	17
SwissProt Accessions	Q15678	Gene names	PTPN14, PEZ
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez).

PTN14_MOUSE
NC score	0.061881 (rank : 68)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	27	Target Neighborhood Hits	142	Shared Neighborhood Hits	15
SwissProt Accessions	Q62130	Gene names	Ptpn14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP36).

PTN21_MOUSE
NC score	0.061618 (rank : 69)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	27	Target Neighborhood Hits	155	Shared Neighborhood Hits	16
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

PTN21_HUMAN
NC score	0.061472 (rank : 70)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	27	Target Neighborhood Hits	143	Shared Neighborhood Hits	15
SwissProt Accessions	Q16825	Gene names	PTPN21, PTPD1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1).

PTPRS_HUMAN
NC score	0.059930 (rank : 71)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	27	Target Neighborhood Hits	472	Shared Neighborhood Hits	22
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

PTN13_MOUSE
NC score	0.059638 (rank : 72)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	27	Target Neighborhood Hits	426	Shared Neighborhood Hits	19
SwissProt Accessions	Q64512, Q61494, Q62135, Q64499	Gene names	Ptpn13, Ptp14
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein tyrosine phosphatase PTP-BL) (Protein-tyrosine phosphatase RIP) (protein tyrosine phosphatase DPZPTP) (PTP36).

PTPRD_HUMAN
NC score	0.058739 (rank : 73)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	27	Target Neighborhood Hits	485	Shared Neighborhood Hits	22
SwissProt Accessions	P23468	Gene names	PTPRD
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

PTPRF_HUMAN
NC score	0.058518 (rank : 74)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	27	Target Neighborhood Hits	489	Shared Neighborhood Hits	22
SwissProt Accessions	P10586	Gene names	PTPRF, LAR
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase F precursor (EC 3.1.3.48) (LAR protein) (Leukocyte antigen related).

PTN13_HUMAN
NC score	0.058452 (rank : 75)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	27	Target Neighborhood Hits	471	Shared Neighborhood Hits	19
SwissProt Accessions	Q12923, Q15159, Q15263, Q15264, Q15265, Q15674, Q16826, Q8IWH7, Q9NYN9	Gene names	PTPN13, PNP1, PTP1E, PTPL1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (PTP-BAS) (Protein-tyrosine phosphatase PTPL1) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1).

PTPRD_MOUSE
NC score	0.058065 (rank : 76)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	27	Target Neighborhood Hits	491	Shared Neighborhood Hits	22
SwissProt Accessions	Q64487, Q64486, Q64488, Q64495	Gene names	Ptprd
Domain Architecture	No domain graphic available
Description	Receptor-type tyrosine-protein phosphatase delta precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase delta) (R-PTP-delta).

UBP34_MOUSE
NC score	0.028210 (rank : 77)	θ value	6.88961 (rank : 25)
Query Neighborhood Hits	27	Target Neighborhood Hits	189	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_HUMAN
NC score	0.028075 (rank : 78)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	27	Target Neighborhood Hits	210	Shared Neighborhood Hits	3
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

PAPPA_MOUSE
NC score	0.026744 (rank : 79)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	27	Target Neighborhood Hits	153	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

DUS12_MOUSE
NC score	0.020947 (rank : 80)	θ value	6.88961 (rank : 23)
Query Neighborhood Hits	27	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D0T2, Q9EQD3	Gene names	Dusp12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity phosphatase T-DSP4) (Dual specificity phosphatase VH1).

ATM_HUMAN
NC score	0.016465 (rank : 81)	θ value	8.99809 (rank : 26)
Query Neighborhood Hits	27	Target Neighborhood Hits	78	Shared Neighborhood Hits	2
SwissProt Accessions	Q13315, O15429, Q12758, Q16551, Q93007, Q9NP02, Q9UCX7	Gene names	ATM
Domain Architecture
Description	Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T, mutated).