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Network neighborhood for query Sequence : DPOLL_MOUSE

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DPOLL_MOUSE
SwissProt Accessions	Q9QXE2, Q9CTJ1	Gene names	Poll, Polk
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DPOLL_HUMAN
θ value	0 (rank : 1)	NC score	0.985387 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UGP5, Q5JQP5, Q6NUM2, Q9HA10, Q9HB35	Gene names	POLL
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa) (DNA polymerase beta-2) (Pol beta2).

DPOLL_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QXE2, Q9CTJ1	Gene names	Poll, Polk
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa).

DPOLB_MOUSE
θ value	2.85459e-46 (rank : 3)	NC score	0.874461 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K409, Q3UAB6, Q922Z7	Gene names	Polb
Domain Architecture
Description	DNA polymerase beta (EC 2.7.7.7) (EC 4.2.99.-).

DPOLB_HUMAN
θ value	3.72821e-46 (rank : 4)	NC score	0.873157 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	P06746, Q6FI34	Gene names	POLB
Domain Architecture
Description	DNA polymerase beta (EC 2.7.7.7) (EC 4.2.99.-).

DPOLM_HUMAN
θ value	3.99248e-40 (rank : 5)	NC score	0.832994 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NP87	Gene names	POLM
Domain Architecture
Description	DNA polymerase mu (EC 2.7.7.7) (Pol Mu).

DPOLM_MOUSE
θ value	7.52953e-39 (rank : 6)	NC score	0.832447 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIW4, Q9JJW9	Gene names	Polm
Domain Architecture
Description	DNA polymerase mu (EC 2.7.7.7) (Pol Mu).

TDT_MOUSE
θ value	6.59618e-35 (rank : 7)	NC score	0.800468 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P09838, Q99PD0, Q99PD1	Gene names	Dntt, Tdt
Domain Architecture
Description	DNA nucleotidylexotransferase (EC 2.7.7.31) (Terminal addition enzyme) (Terminal deoxynucleotidyltransferase) (TDT) (Terminal transferase).

TDT_HUMAN
θ value	8.63488e-27 (rank : 8)	NC score	0.782462 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	P04053, Q96E50	Gene names	DNTT, TDT
Domain Architecture
Description	DNA nucleotidylexotransferase (EC 2.7.7.31) (Terminal addition enzyme) (Terminal deoxynucleotidyltransferase) (Terminal transferase).

CBP_HUMAN
θ value	0.0330416 (rank : 9)	NC score	0.038045 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	941	Shared Neighborhood Hits	21
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

NOLC1_HUMAN
θ value	0.0961366 (rank : 10)	NC score	0.047966 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	452	Shared Neighborhood Hits	14
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

MAGE1_HUMAN
θ value	0.163984 (rank : 11)	NC score	0.032925 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	1389	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

TSKS_HUMAN
θ value	0.279714 (rank : 12)	NC score	0.040463 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	220	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJT2, Q8WXJ0	Gene names	STK22S1, TSKS, TSKS1
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

IWS1_HUMAN
θ value	0.365318 (rank : 13)	NC score	0.029166 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	1241	Shared Neighborhood Hits	25
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ZCPW1_MOUSE
θ value	0.47712 (rank : 14)	NC score	0.038718 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	307	Shared Neighborhood Hits	10
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

BSN_MOUSE
θ value	0.62314 (rank : 15)	NC score	0.028543 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	2057	Shared Neighborhood Hits	40
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

PKHG1_HUMAN
θ value	0.62314 (rank : 16)	NC score	0.020304 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	174	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

RP3A_MOUSE
θ value	0.62314 (rank : 17)	NC score	0.021321 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	510	Shared Neighborhood Hits	17
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

ACM4_HUMAN
θ value	0.813845 (rank : 18)	NC score	0.008972 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	889	Shared Neighborhood Hits	3
SwissProt Accessions	P08173	Gene names	CHRM4
Domain Architecture
Description	Muscarinic acetylcholine receptor M4.

DNL4_MOUSE
θ value	0.813845 (rank : 19)	NC score	0.029301 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BTF7, Q3UG76	Gene names	Lig4
Domain Architecture	No domain graphic available
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

ACM4_MOUSE
θ value	1.06291 (rank : 20)	NC score	0.008707 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	894	Shared Neighborhood Hits	3
SwissProt Accessions	P32211, Q64056	Gene names	Chrm4, Chrm-4
Domain Architecture
Description	Muscarinic acetylcholine receptor M4 (Mm4 mAChR).

BASP_HUMAN
θ value	1.06291 (rank : 21)	NC score	0.035375 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	321	Shared Neighborhood Hits	11
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BAT2_MOUSE
θ value	1.38821 (rank : 22)	NC score	0.032367 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	947	Shared Neighborhood Hits	35
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

FMNL_MOUSE
θ value	1.38821 (rank : 23)	NC score	0.022519 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	428	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

TE2IP_MOUSE
θ value	1.38821 (rank : 24)	NC score	0.032592 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q91VL8, Q543F4, Q9JJE8, Q9JJE9	Gene names	Terf2ip, Rap1
Domain Architecture	No domain graphic available
Description	Telomeric repeat-binding factor 2-interacting protein 1 (TRF2- interacting telomeric protein Rap1).

CSKI1_MOUSE
θ value	1.81305 (rank : 25)	NC score	0.012969 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	1031	Shared Neighborhood Hits	25
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

MADCA_HUMAN
θ value	2.36792 (rank : 26)	NC score	0.033497 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	221	Shared Neighborhood Hits	12
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MUC2_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.016781 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	906	Shared Neighborhood Hits	17
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

DCAK1_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.000868 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	877	Shared Neighborhood Hits	6
SwissProt Accessions	O15075	Gene names	DCAMKL1, KIAA0369
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).

LCP2_HUMAN
θ value	3.0926 (rank : 29)	NC score	0.023872 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	531	Shared Neighborhood Hits	21
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

PO2F2_MOUSE
θ value	3.0926 (rank : 30)	NC score	0.008607 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	353	Shared Neighborhood Hits	7
SwissProt Accessions	Q00196, Q00197, Q00198, Q00199, Q00200, Q00201, Q05882, Q61995, Q61996, Q64245	Gene names	Pou2f2, Oct2, Otf2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

TIF1B_HUMAN
θ value	3.0926 (rank : 31)	NC score	0.012887 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	312	Shared Neighborhood Hits	5
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TMC2_HUMAN
θ value	3.0926 (rank : 32)	NC score	0.015376 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	149	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

ZC11A_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.022661 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

ATBF1_HUMAN
θ value	4.03905 (rank : 34)	NC score	0.006344 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	1547	Shared Neighborhood Hits	21
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

DAB2_HUMAN
θ value	4.03905 (rank : 35)	NC score	0.019024 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	197	Shared Neighborhood Hits	8
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

IWS1_MOUSE
θ value	4.03905 (rank : 36)	NC score	0.029215 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	1258	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

PRG4_HUMAN
θ value	4.03905 (rank : 37)	NC score	0.019939 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	764	Shared Neighborhood Hits	24
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

REXO1_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.016942 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	242	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

RP3A_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.015112 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	305	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

3BP1_HUMAN
θ value	5.27518 (rank : 40)	NC score	0.014634 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	376	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

BRSK1_HUMAN
θ value	5.27518 (rank : 41)	NC score	0.000587 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	942	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

FHOD1_MOUSE
θ value	5.27518 (rank : 42)	NC score	0.015949 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	217	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

IRX3_MOUSE
θ value	5.27518 (rank : 43)	NC score	0.008389 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	303	Shared Neighborhood Hits	4
SwissProt Accessions	P81067	Gene names	Irx3, Irxb1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

LIPB2_HUMAN
θ value	5.27518 (rank : 44)	NC score	0.008153 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	599	Shared Neighborhood Hits	10
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

SNPC2_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.020128 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q13487, Q13486	Gene names	SNAPC2, SNAP45
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2) (Proximal sequence element-binding transcription factor subunit delta) (PSE- binding factor subunit delta) (PTF subunit delta).

WWP2_HUMAN
θ value	5.27518 (rank : 46)	NC score	0.008140 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	177	Shared Neighborhood Hits	10
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

AN13D_HUMAN
θ value	6.88961 (rank : 47)	NC score	0.008748 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZTN6, Q6ZVD0, Q86SU1	Gene names	ANKRD13D
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

ASPP1_MOUSE
θ value	6.88961 (rank : 48)	NC score	0.010297 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	1244	Shared Neighborhood Hits	23
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

BAG3_MOUSE
θ value	6.88961 (rank : 49)	NC score	0.019004 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	513	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

DACT1_MOUSE
θ value	6.88961 (rank : 50)	NC score	0.017864 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R4A3, Q80VG9, Q8BP49, Q9JK89	Gene names	Dact1, Thyex3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (MDpr1) (Frodo) (Thymus-expressed novel gene 3 protein).

IF4G1_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.016201 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	347	Shared Neighborhood Hits	12
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

IF4G1_MOUSE
θ value	6.88961 (rank : 52)	NC score	0.020714 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	534	Shared Neighborhood Hits	17
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

K1543_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.019071 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	435	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MILK2_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.011348 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	457	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

MYLK2_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.000697 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	920	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

PAX5_MOUSE
θ value	6.88961 (rank : 56)	NC score	0.009425 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	106	Shared Neighborhood Hits	5
SwissProt Accessions	Q02650	Gene names	Pax5, Pax-5
Domain Architecture
Description	Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP).

REPS2_MOUSE
θ value	6.88961 (rank : 57)	NC score	0.011167 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

SIN3A_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.010628 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	180	Shared Neighborhood Hits	9
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

ST18_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.008526 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	252	Shared Neighborhood Hits	4
SwissProt Accessions	O60284	Gene names	ST18, KIAA0535, ZNF387
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18 (Zinc finger protein 387).

TCOF_MOUSE
θ value	6.88961 (rank : 60)	NC score	0.019487 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	471	Shared Neighborhood Hits	15
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

TRIPC_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.010809 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	319	Shared Neighborhood Hits	9
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

2A5D_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.007031 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q14738, O00494, O00696, Q15171	Gene names	PPP2R5D
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A, B subunit, B' delta isoform) (PP2A, B subunit, B56 delta isoform) (PP2A, B subunit, PR61 delta isoform) (PP2A, B subunit, R5 delta isoform).

3BP1_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.011125 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	238	Shared Neighborhood Hits	12
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

BAZ2A_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.013829 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	744	Shared Neighborhood Hits	26
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CSKI1_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.009495 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	997	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

PAX5_HUMAN
θ value	8.99809 (rank : 66)	NC score	0.008713 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	106	Shared Neighborhood Hits	5
SwissProt Accessions	Q02548, O75933	Gene names	PAX5
Domain Architecture
Description	Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP).

PRG4_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.017901 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	624	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

RTN1_MOUSE
θ value	8.99809 (rank : 68)	NC score	0.011746 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	189	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

UBP31_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.007763 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	293	Shared Neighborhood Hits	10
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

X3CL1_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.013938 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	P78423, O00672	Gene names	CX3CL1, A-152E5.2, FKN, NTT, SCYD1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

ZC3H3_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.011519 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	159	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

Hits sorted by NC score

DPOLL_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QXE2, Q9CTJ1	Gene names	Poll, Polk
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa).

DPOLL_HUMAN
NC score	0.985387 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UGP5, Q5JQP5, Q6NUM2, Q9HA10, Q9HB35	Gene names	POLL
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa) (DNA polymerase beta-2) (Pol beta2).

DPOLB_MOUSE
NC score	0.874461 (rank : 3)	θ value	2.85459e-46 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K409, Q3UAB6, Q922Z7	Gene names	Polb
Domain Architecture
Description	DNA polymerase beta (EC 2.7.7.7) (EC 4.2.99.-).

DPOLB_HUMAN
NC score	0.873157 (rank : 4)	θ value	3.72821e-46 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	P06746, Q6FI34	Gene names	POLB
Domain Architecture
Description	DNA polymerase beta (EC 2.7.7.7) (EC 4.2.99.-).

DPOLM_HUMAN
NC score	0.832994 (rank : 5)	θ value	3.99248e-40 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NP87	Gene names	POLM
Domain Architecture
Description	DNA polymerase mu (EC 2.7.7.7) (Pol Mu).

DPOLM_MOUSE
NC score	0.832447 (rank : 6)	θ value	7.52953e-39 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIW4, Q9JJW9	Gene names	Polm
Domain Architecture
Description	DNA polymerase mu (EC 2.7.7.7) (Pol Mu).

TDT_MOUSE
NC score	0.800468 (rank : 7)	θ value	6.59618e-35 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	11	Shared Neighborhood Hits	8
SwissProt Accessions	P09838, Q99PD0, Q99PD1	Gene names	Dntt, Tdt
Domain Architecture
Description	DNA nucleotidylexotransferase (EC 2.7.7.31) (Terminal addition enzyme) (Terminal deoxynucleotidyltransferase) (TDT) (Terminal transferase).

TDT_HUMAN
NC score	0.782462 (rank : 8)	θ value	8.63488e-27 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	P04053, Q96E50	Gene names	DNTT, TDT
Domain Architecture
Description	DNA nucleotidylexotransferase (EC 2.7.7.31) (Terminal addition enzyme) (Terminal deoxynucleotidyltransferase) (Terminal transferase).

NOLC1_HUMAN
NC score	0.047966 (rank : 9)	θ value	0.0961366 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	452	Shared Neighborhood Hits	14
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

TSKS_HUMAN
NC score	0.040463 (rank : 10)	θ value	0.279714 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	220	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJT2, Q8WXJ0	Gene names	STK22S1, TSKS, TSKS1
Domain Architecture	No domain graphic available
Description	Testis-specific serine kinase substrate (Testis-specific kinase substrate) (STK22 substrate 1).

ZCPW1_MOUSE
NC score	0.038718 (rank : 11)	θ value	0.47712 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	307	Shared Neighborhood Hits	10
SwissProt Accessions	Q6IR42	Gene names	Zcwpw1
Domain Architecture	No domain graphic available
Description	Zinc finger CW-type PWWP domain protein 1 homolog.

CBP_HUMAN
NC score	0.038045 (rank : 12)	θ value	0.0330416 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	941	Shared Neighborhood Hits	21
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

BASP_HUMAN
NC score	0.035375 (rank : 13)	θ value	1.06291 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	321	Shared Neighborhood Hits	11
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

MADCA_HUMAN
NC score	0.033497 (rank : 14)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	221	Shared Neighborhood Hits	12
SwissProt Accessions	Q13477, O60222, O75867	Gene names	MADCAM1
Domain Architecture	No domain graphic available
Description	Mucosal addressin cell adhesion molecule 1 precursor (MAdCAM-1) (hMAdCAM-1).

MAGE1_HUMAN
NC score	0.032925 (rank : 15)	θ value	0.163984 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	1389	Shared Neighborhood Hits	41
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

TE2IP_MOUSE
NC score	0.032592 (rank : 16)	θ value	1.38821 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q91VL8, Q543F4, Q9JJE8, Q9JJE9	Gene names	Terf2ip, Rap1
Domain Architecture	No domain graphic available
Description	Telomeric repeat-binding factor 2-interacting protein 1 (TRF2- interacting telomeric protein Rap1).

BAT2_MOUSE
NC score	0.032367 (rank : 17)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	947	Shared Neighborhood Hits	35
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

DNL4_MOUSE
NC score	0.029301 (rank : 18)	θ value	0.813845 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BTF7, Q3UG76	Gene names	Lig4
Domain Architecture	No domain graphic available
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

IWS1_MOUSE
NC score	0.029215 (rank : 19)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	1258	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_HUMAN
NC score	0.029166 (rank : 20)	θ value	0.365318 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	1241	Shared Neighborhood Hits	25
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

BSN_MOUSE
NC score	0.028543 (rank : 21)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	2057	Shared Neighborhood Hits	40
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

LCP2_HUMAN
NC score	0.023872 (rank : 22)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	531	Shared Neighborhood Hits	21
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

ZC11A_HUMAN
NC score	0.022661 (rank : 23)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	170	Shared Neighborhood Hits	7
SwissProt Accessions	O75152, Q6AHY4, Q6AHY9, Q6AW79, Q6AWA1, Q6PJK4, Q86XZ7	Gene names	ZC3H11A, KIAA0663
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 11A.

FMNL_MOUSE
NC score	0.022519 (rank : 24)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	428	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JL26, Q6KAN4, Q9Z2V7	Gene names	Fmnl1, Frl
Domain Architecture	No domain graphic available
Description	Formin-like protein 1 (Formin-related protein).

RP3A_MOUSE
NC score	0.021321 (rank : 25)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	510	Shared Neighborhood Hits	17
SwissProt Accessions	P47708	Gene names	Rph3a
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

IF4G1_MOUSE
NC score	0.020714 (rank : 26)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	534	Shared Neighborhood Hits	17
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

PKHG1_HUMAN
NC score	0.020304 (rank : 27)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	174	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

SNPC2_HUMAN
NC score	0.020128 (rank : 28)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q13487, Q13486	Gene names	SNAPC2, SNAP45
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 2 (SNAPc subunit 2) (snRNA- activating protein complex 45 kDa subunit) (SNAPc 45 kDa subunit) (Small nuclear RNA-activating complex polypeptide 2) (Proximal sequence element-binding transcription factor subunit delta) (PSE- binding factor subunit delta) (PTF subunit delta).

PRG4_HUMAN
NC score	0.019939 (rank : 29)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	764	Shared Neighborhood Hits	24
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

TCOF_MOUSE
NC score	0.019487 (rank : 30)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	471	Shared Neighborhood Hits	15
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

K1543_HUMAN
NC score	0.019071 (rank : 31)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	435	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

DAB2_HUMAN
NC score	0.019024 (rank : 32)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	197	Shared Neighborhood Hits	8
SwissProt Accessions	P98082, Q13598, Q9BTY0, Q9UK04	Gene names	DAB2, DOC2
Domain Architecture
Description	Disabled homolog 2 (Differentially expressed protein 2) (DOC-2).

BAG3_MOUSE
NC score	0.019004 (rank : 33)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	513	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

PRG4_MOUSE
NC score	0.017901 (rank : 34)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	624	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

DACT1_MOUSE
NC score	0.017864 (rank : 35)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R4A3, Q80VG9, Q8BP49, Q9JK89	Gene names	Dact1, Thyex3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (MDpr1) (Frodo) (Thymus-expressed novel gene 3 protein).

REXO1_HUMAN
NC score	0.016942 (rank : 36)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	242	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N1G1, Q9ULT2	Gene names	REXO1, ELOABP1, KIAA1138, TCEB3BP1
Domain Architecture	No domain graphic available
Description	RNA exonuclease 1 homolog (EC 3.1.-.-) (Elongin A-binding protein 1) (EloA-BP1) (Transcription elongation factor B polypeptide 3-binding protein 1).

MUC2_HUMAN
NC score	0.016781 (rank : 37)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	906	Shared Neighborhood Hits	17
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

IF4G1_HUMAN
NC score	0.016201 (rank : 38)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	347	Shared Neighborhood Hits	12
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

FHOD1_MOUSE
NC score	0.015949 (rank : 39)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	217	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P9Q4, Q8BMK2	Gene names	Fhod1, Fhos1
Domain Architecture	No domain graphic available
Description	FH1/FH2 domain-containing protein (Formin homolog overexpressed in spleen) (FHOS) (Formin homology 2 domain-containing protein 1).

TMC2_HUMAN
NC score	0.015376 (rank : 40)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	149	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TDI7, Q5JXT0, Q5JXT1, Q6UWW4, Q6ZS41, Q8N9F3, Q9BYN2, Q9BYN3, Q9BYN4, Q9BYN5	Gene names	TMC2
Domain Architecture	No domain graphic available
Description	Transmembrane cochlear-expressed protein 2.

RP3A_HUMAN
NC score	0.015112 (rank : 41)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	305	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y2J0, Q96AE0	Gene names	RPH3A, KIAA0985
Domain Architecture
Description	Rabphilin-3A (Exophilin-1).

3BP1_HUMAN
NC score	0.014634 (rank : 42)	θ value	5.27518 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	376	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

X3CL1_HUMAN
NC score	0.013938 (rank : 43)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	P78423, O00672	Gene names	CX3CL1, A-152E5.2, FKN, NTT, SCYD1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

BAZ2A_MOUSE
NC score	0.013829 (rank : 44)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	744	Shared Neighborhood Hits	26
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CSKI1_MOUSE
NC score	0.012969 (rank : 45)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	1031	Shared Neighborhood Hits	25
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

TIF1B_HUMAN
NC score	0.012887 (rank : 46)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	312	Shared Neighborhood Hits	5
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

RTN1_MOUSE
NC score	0.011746 (rank : 47)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	189	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

ZC3H3_HUMAN
NC score	0.011519 (rank : 48)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	159	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IXZ2, Q14163, Q8N4E2, Q9BUS4	Gene names	ZC3H3, KIAA0150, ZC3HDC3
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 3.

MILK2_HUMAN
NC score	0.011348 (rank : 49)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	457	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

REPS2_MOUSE
NC score	0.011167 (rank : 50)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	102	Shared Neighborhood Hits	3
SwissProt Accessions	Q80XA6	Gene names	Reps2, Pob1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 2 (RalBP1-interacting protein 2) (Partner of RalBP1).

3BP1_MOUSE
NC score	0.011125 (rank : 51)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	238	Shared Neighborhood Hits	12
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

TRIPC_HUMAN
NC score	0.010809 (rank : 52)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	319	Shared Neighborhood Hits	9
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

SIN3A_HUMAN
NC score	0.010628 (rank : 53)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	180	Shared Neighborhood Hits	9
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

ASPP1_MOUSE
NC score	0.010297 (rank : 54)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	1244	Shared Neighborhood Hits	23
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

CSKI1_HUMAN
NC score	0.009495 (rank : 55)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	997	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

PAX5_MOUSE
NC score	0.009425 (rank : 56)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	106	Shared Neighborhood Hits	5
SwissProt Accessions	Q02650	Gene names	Pax5, Pax-5
Domain Architecture
Description	Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP).

ACM4_HUMAN
NC score	0.008972 (rank : 57)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	889	Shared Neighborhood Hits	3
SwissProt Accessions	P08173	Gene names	CHRM4
Domain Architecture
Description	Muscarinic acetylcholine receptor M4.

AN13D_HUMAN
NC score	0.008748 (rank : 58)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZTN6, Q6ZVD0, Q86SU1	Gene names	ANKRD13D
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 13D.

PAX5_HUMAN
NC score	0.008713 (rank : 59)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	106	Shared Neighborhood Hits	5
SwissProt Accessions	Q02548, O75933	Gene names	PAX5
Domain Architecture
Description	Paired box protein Pax-5 (B-cell-specific transcription factor) (BSAP).

ACM4_MOUSE
NC score	0.008707 (rank : 60)	θ value	1.06291 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	894	Shared Neighborhood Hits	3
SwissProt Accessions	P32211, Q64056	Gene names	Chrm4, Chrm-4
Domain Architecture
Description	Muscarinic acetylcholine receptor M4 (Mm4 mAChR).

PO2F2_MOUSE
NC score	0.008607 (rank : 61)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	353	Shared Neighborhood Hits	7
SwissProt Accessions	Q00196, Q00197, Q00198, Q00199, Q00200, Q00201, Q05882, Q61995, Q61996, Q64245	Gene names	Pou2f2, Oct2, Otf2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

ST18_HUMAN
NC score	0.008526 (rank : 62)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	252	Shared Neighborhood Hits	4
SwissProt Accessions	O60284	Gene names	ST18, KIAA0535, ZNF387
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity protein 18 (Zinc finger protein 387).

IRX3_MOUSE
NC score	0.008389 (rank : 63)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	303	Shared Neighborhood Hits	4
SwissProt Accessions	P81067	Gene names	Irx3, Irxb1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

LIPB2_HUMAN
NC score	0.008153 (rank : 64)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	599	Shared Neighborhood Hits	10
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

WWP2_HUMAN
NC score	0.008140 (rank : 65)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	177	Shared Neighborhood Hits	10
SwissProt Accessions	O00308, Q96CZ2, Q9BWN6	Gene names	WWP2
Domain Architecture
Description	NEDD4-like E3 ubiquitin-protein ligase WWP2 (EC 6.3.2.-) (WW domain- containing protein 2) (Atrophin-1-interacting protein 2) (AIP2).

UBP31_HUMAN
NC score	0.007763 (rank : 66)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	293	Shared Neighborhood Hits	10
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

2A5D_HUMAN
NC score	0.007031 (rank : 67)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	59	Shared Neighborhood Hits	5
SwissProt Accessions	Q14738, O00494, O00696, Q15171	Gene names	PPP2R5D
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A, B subunit, B' delta isoform) (PP2A, B subunit, B56 delta isoform) (PP2A, B subunit, PR61 delta isoform) (PP2A, B subunit, R5 delta isoform).

ATBF1_HUMAN
NC score	0.006344 (rank : 68)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	1547	Shared Neighborhood Hits	21
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

DCAK1_HUMAN
NC score	0.000868 (rank : 69)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	877	Shared Neighborhood Hits	6
SwissProt Accessions	O15075	Gene names	DCAMKL1, KIAA0369
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase DCAMKL1 (EC 2.7.11.1) (Doublecortin- like and CAM kinase-like 1).

MYLK2_HUMAN
NC score	0.000697 (rank : 70)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	920	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H1R3, Q96I84	Gene names	MYLK2
Domain Architecture
Description	Myosin light chain kinase 2, skeletal/cardiac muscle (EC 2.7.11.18) (MLCK2).

BRSK1_HUMAN
NC score	0.000587 (rank : 71)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	942	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).