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Network neighborhood for query Sequence : SAMD8_HUMAN

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SAMD8_HUMAN
SwissProt Accessions	Q96LT4	Gene names	SAMD8
Domain Architecture
Description	Sphingomyelin synthase-related protein 1 (Sterile alpha motif domain- containing 8).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SAMD8_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q96LT4	Gene names	SAMD8
Domain Architecture
Description	Sphingomyelin synthase-related protein 1 (Sterile alpha motif domain- containing 8).

SAMD8_MOUSE
θ value	0 (rank : 2)	NC score	0.999077 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DA37	Gene names	Samd8
Domain Architecture
Description	Sphingomyelin synthase-related protein 1 (Sterile alpha motif domain- containing 8).

SMS1_HUMAN
θ value	1.04096e-72 (rank : 3)	NC score	0.931520 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q86VZ5	Gene names	TMEM23, MOB
Domain Architecture
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 1 (EC 2.7.-.-) (Transmembrane protein 23) (Sphingomyelin synthase 1) (Mob protein).

SMS1_MOUSE
θ value	6.7473e-72 (rank : 4)	NC score	0.930586 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VCQ6, Q8C464, Q8C583, Q8C652	Gene names	Tmem23
Domain Architecture
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 1 (EC 2.7.-.-) (Transmembrane protein 23) (Sphingomyelin synthase 1) (Mob protein).

SMS2_HUMAN
θ value	4.52582e-68 (rank : 5)	NC score	0.932876 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NHU3	Gene names
Domain Architecture	No domain graphic available
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 2 (EC 2.7.-.-) (Sphingomyelin synthase 2).

SMS2_MOUSE
θ value	2.24614e-67 (rank : 6)	NC score	0.932721 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D4B1	Gene names
Domain Architecture	No domain graphic available
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 2 (EC 2.7.-.-) (Sphingomyelin synthase 2).

DGKD_HUMAN
θ value	0.00509761 (rank : 7)	NC score	0.086137 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	231	Shared Neighborhood Hits	10
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

DGKH_HUMAN
θ value	0.00665767 (rank : 8)	NC score	0.085350 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	255	Shared Neighborhood Hits	12
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

LIPB2_HUMAN
θ value	0.0563607 (rank : 9)	NC score	0.067483 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	599	Shared Neighborhood Hits	12
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

LIPB2_MOUSE
θ value	0.0961366 (rank : 10)	NC score	0.064605 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	570	Shared Neighborhood Hits	11
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

CSKI1_HUMAN
θ value	0.365318 (rank : 11)	NC score	0.029635 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	997	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_MOUSE
θ value	0.62314 (rank : 12)	NC score	0.030805 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	1031	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

SARM1_MOUSE
θ value	0.813845 (rank : 13)	NC score	0.059876 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	54	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

TLR13_MOUSE
θ value	1.81305 (rank : 14)	NC score	0.013659 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	335	Shared Neighborhood Hits	5
SwissProt Accessions	Q6R5N8, Q3TDS2	Gene names	Tlr13
Domain Architecture	No domain graphic available
Description	Toll-like receptor 13 precursor.

BFAR_HUMAN
θ value	3.0926 (rank : 15)	NC score	0.034084 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	222	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

PKCB1_HUMAN
θ value	4.03905 (rank : 16)	NC score	0.020318 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	488	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

SAMH1_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.031488 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3Z3, Q5JXG8, Q9H004, Q9H005, Q9H3U9	Gene names	SAMHD1, MOP5
Domain Architecture
Description	SAM domain and HD domain-containing protein 1 (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5).

LIPB1_HUMAN
θ value	5.27518 (rank : 18)	NC score	0.048979 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	640	Shared Neighborhood Hits	12
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

LIPB1_MOUSE
θ value	5.27518 (rank : 19)	NC score	0.044358 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	727	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

SLIK5_MOUSE
θ value	5.27518 (rank : 20)	NC score	0.007788 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	301	Shared Neighborhood Hits	4
SwissProt Accessions	Q810B7, Q9CT21	Gene names	Slitrk5
Domain Architecture
Description	SLIT and NTRK-like protein 5 precursor.

BFAR_MOUSE
θ value	8.99809 (rank : 21)	NC score	0.022013 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	232	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

SLIK5_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.006953 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	302	Shared Neighborhood Hits	4
SwissProt Accessions	O94991	Gene names	SLITRK5, KIAA0918, LRRC11
Domain Architecture
Description	SLIT and NTRK-like protein 5 precursor (Leucine-rich repeat-containing protein 11).

Hits sorted by NC score

SAMD8_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q96LT4	Gene names	SAMD8
Domain Architecture
Description	Sphingomyelin synthase-related protein 1 (Sterile alpha motif domain- containing 8).

SAMD8_MOUSE
NC score	0.999077 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	20
SwissProt Accessions	Q9DA37	Gene names	Samd8
Domain Architecture
Description	Sphingomyelin synthase-related protein 1 (Sterile alpha motif domain- containing 8).

SMS2_HUMAN
NC score	0.932876 (rank : 3)	θ value	4.52582e-68 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NHU3	Gene names
Domain Architecture	No domain graphic available
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 2 (EC 2.7.-.-) (Sphingomyelin synthase 2).

SMS2_MOUSE
NC score	0.932721 (rank : 4)	θ value	2.24614e-67 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D4B1	Gene names
Domain Architecture	No domain graphic available
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 2 (EC 2.7.-.-) (Sphingomyelin synthase 2).

SMS1_HUMAN
NC score	0.931520 (rank : 5)	θ value	1.04096e-72 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q86VZ5	Gene names	TMEM23, MOB
Domain Architecture
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 1 (EC 2.7.-.-) (Transmembrane protein 23) (Sphingomyelin synthase 1) (Mob protein).

SMS1_MOUSE
NC score	0.930586 (rank : 6)	θ value	6.7473e-72 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VCQ6, Q8C464, Q8C583, Q8C652	Gene names	Tmem23
Domain Architecture
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 1 (EC 2.7.-.-) (Transmembrane protein 23) (Sphingomyelin synthase 1) (Mob protein).

DGKD_HUMAN
NC score	0.086137 (rank : 7)	θ value	0.00509761 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	231	Shared Neighborhood Hits	10
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

DGKH_HUMAN
NC score	0.085350 (rank : 8)	θ value	0.00665767 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	255	Shared Neighborhood Hits	12
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

LIPB2_HUMAN
NC score	0.067483 (rank : 9)	θ value	0.0563607 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	599	Shared Neighborhood Hits	12
SwissProt Accessions	Q8ND30, O75337, Q8WW26	Gene names	PPFIBP2
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2).

LIPB2_MOUSE
NC score	0.064605 (rank : 10)	θ value	0.0961366 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	570	Shared Neighborhood Hits	11
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

SARM1_MOUSE
NC score	0.059876 (rank : 11)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	54	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PDS3, Q5SYG5, Q5SYG6, Q6A054, Q6SZW0, Q8BRI9	Gene names	Sarm1, Kiaa0524
Domain Architecture	No domain graphic available
Description	Sterile alpha and TIR motif-containing protein 1 (Tir-1 homolog).

LIPB1_HUMAN
NC score	0.048979 (rank : 12)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	640	Shared Neighborhood Hits	12
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

LIPB1_MOUSE
NC score	0.044358 (rank : 13)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	727	Shared Neighborhood Hits	12
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

BFAR_HUMAN
NC score	0.034084 (rank : 14)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	222	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NZS9	Gene names	BFAR, BAR, RNF47
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator (RING finger protein 47).

SAMH1_HUMAN
NC score	0.031488 (rank : 15)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y3Z3, Q5JXG8, Q9H004, Q9H005, Q9H3U9	Gene names	SAMHD1, MOP5
Domain Architecture
Description	SAM domain and HD domain-containing protein 1 (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5).

CSKI1_MOUSE
NC score	0.030805 (rank : 16)	θ value	0.62314 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	1031	Shared Neighborhood Hits	9
SwissProt Accessions	Q6P9K8, Q6ZPU2, Q8BWU2, Q8BX99, Q9CXH0	Gene names	Caskin1, Kiaa1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CSKI1_HUMAN
NC score	0.029635 (rank : 17)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	997	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

BFAR_MOUSE
NC score	0.022013 (rank : 18)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	232	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R079, Q8C1A7, Q9CXY3	Gene names	Bfar
Domain Architecture	No domain graphic available
Description	Bifunctional apoptosis regulator.

PKCB1_HUMAN
NC score	0.020318 (rank : 19)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	488	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

TLR13_MOUSE
NC score	0.013659 (rank : 20)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	335	Shared Neighborhood Hits	5
SwissProt Accessions	Q6R5N8, Q3TDS2	Gene names	Tlr13
Domain Architecture	No domain graphic available
Description	Toll-like receptor 13 precursor.

SLIK5_MOUSE
NC score	0.007788 (rank : 21)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	301	Shared Neighborhood Hits	4
SwissProt Accessions	Q810B7, Q9CT21	Gene names	Slitrk5
Domain Architecture
Description	SLIT and NTRK-like protein 5 precursor.

SLIK5_HUMAN
NC score	0.006953 (rank : 22)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	302	Shared Neighborhood Hits	4
SwissProt Accessions	O94991	Gene names	SLITRK5, KIAA0918, LRRC11
Domain Architecture
Description	SLIT and NTRK-like protein 5 precursor (Leucine-rich repeat-containing protein 11).