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Network neighborhood for query Sequence : SMS2_HUMAN

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SMS2_HUMAN
SwissProt Accessions	Q8NHU3	Gene names
Domain Architecture	No domain graphic available
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 2 (EC 2.7.-.-) (Sphingomyelin synthase 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SMS2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NHU3	Gene names
Domain Architecture	No domain graphic available
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 2 (EC 2.7.-.-) (Sphingomyelin synthase 2).

SMS2_MOUSE
θ value	0 (rank : 2)	NC score	0.998965 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D4B1	Gene names
Domain Architecture	No domain graphic available
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 2 (EC 2.7.-.-) (Sphingomyelin synthase 2).

SMS1_MOUSE
θ value	2.88631e-123 (rank : 3)	NC score	0.983638 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VCQ6, Q8C464, Q8C583, Q8C652	Gene names	Tmem23
Domain Architecture
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 1 (EC 2.7.-.-) (Transmembrane protein 23) (Sphingomyelin synthase 1) (Mob protein).

SMS1_HUMAN
θ value	2.06847e-121 (rank : 4)	NC score	0.983296 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q86VZ5	Gene names	TMEM23, MOB
Domain Architecture
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 1 (EC 2.7.-.-) (Transmembrane protein 23) (Sphingomyelin synthase 1) (Mob protein).

SAMD8_MOUSE
θ value	1.40689e-69 (rank : 5)	NC score	0.929817 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DA37	Gene names	Samd8
Domain Architecture
Description	Sphingomyelin synthase-related protein 1 (Sterile alpha motif domain- containing 8).

SAMD8_HUMAN
θ value	4.52582e-68 (rank : 6)	NC score	0.932876 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q96LT4	Gene names	SAMD8
Domain Architecture
Description	Sphingomyelin synthase-related protein 1 (Sterile alpha motif domain- containing 8).

EHMT2_MOUSE
θ value	1.06291 (rank : 7)	NC score	0.013445 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	750	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_HUMAN
θ value	1.38821 (rank : 8)	NC score	0.013390 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	498	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

USH2A_HUMAN
θ value	1.38821 (rank : 9)	NC score	0.010609 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	600	Shared Neighborhood Hits	3
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

JHD3A_MOUSE
θ value	6.88961 (rank : 10)	NC score	0.006125 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).

PAQRB_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.023898 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q15546, Q8TAN7	Gene names	MMD, PAQR11
Domain Architecture
Description	Monocyte to macrophage differentiation protein (Progestin and adipoQ receptor family member XI).

PAQRB_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.023940 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQY7, Q3TAU1, Q5SVU7	Gene names	Mmd, Paqr11
Domain Architecture	No domain graphic available
Description	Monocyte to macrophage differentiation protein (Progestin and adipoQ receptor family member XI).

Hits sorted by NC score

SMS2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	12	Target Neighborhood Hits	12	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NHU3	Gene names
Domain Architecture	No domain graphic available
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 2 (EC 2.7.-.-) (Sphingomyelin synthase 2).

SMS2_MOUSE
NC score	0.998965 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	12	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D4B1	Gene names
Domain Architecture	No domain graphic available
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 2 (EC 2.7.-.-) (Sphingomyelin synthase 2).

SMS1_MOUSE
NC score	0.983638 (rank : 3)	θ value	2.88631e-123 (rank : 3)
Query Neighborhood Hits	12	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VCQ6, Q8C464, Q8C583, Q8C652	Gene names	Tmem23
Domain Architecture
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 1 (EC 2.7.-.-) (Transmembrane protein 23) (Sphingomyelin synthase 1) (Mob protein).

SMS1_HUMAN
NC score	0.983296 (rank : 4)	θ value	2.06847e-121 (rank : 4)
Query Neighborhood Hits	12	Target Neighborhood Hits	17	Shared Neighborhood Hits	6
SwissProt Accessions	Q86VZ5	Gene names	TMEM23, MOB
Domain Architecture
Description	Phosphatidylcholine:ceramide cholinephosphotransferase 1 (EC 2.7.-.-) (Transmembrane protein 23) (Sphingomyelin synthase 1) (Mob protein).

SAMD8_HUMAN
NC score	0.932876 (rank : 5)	θ value	4.52582e-68 (rank : 6)
Query Neighborhood Hits	12	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q96LT4	Gene names	SAMD8
Domain Architecture
Description	Sphingomyelin synthase-related protein 1 (Sterile alpha motif domain- containing 8).

SAMD8_MOUSE
NC score	0.929817 (rank : 6)	θ value	1.40689e-69 (rank : 5)
Query Neighborhood Hits	12	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	Q9DA37	Gene names	Samd8
Domain Architecture
Description	Sphingomyelin synthase-related protein 1 (Sterile alpha motif domain- containing 8).

PAQRB_MOUSE
NC score	0.023940 (rank : 7)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	12	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQY7, Q3TAU1, Q5SVU7	Gene names	Mmd, Paqr11
Domain Architecture	No domain graphic available
Description	Monocyte to macrophage differentiation protein (Progestin and adipoQ receptor family member XI).

PAQRB_HUMAN
NC score	0.023898 (rank : 8)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	12	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q15546, Q8TAN7	Gene names	MMD, PAQR11
Domain Architecture
Description	Monocyte to macrophage differentiation protein (Progestin and adipoQ receptor family member XI).

EHMT2_MOUSE
NC score	0.013445 (rank : 9)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	12	Target Neighborhood Hits	750	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_HUMAN
NC score	0.013390 (rank : 10)	θ value	1.38821 (rank : 8)
Query Neighborhood Hits	12	Target Neighborhood Hits	498	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

USH2A_HUMAN
NC score	0.010609 (rank : 11)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	12	Target Neighborhood Hits	600	Shared Neighborhood Hits	3
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

JHD3A_MOUSE
NC score	0.006125 (rank : 12)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	12	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BW72, Q3UKM5, Q3UM81, Q3UWV2, Q6ZQ72, Q8K137	Gene names	Jmjd2a, Jhdm3a, Jmjd2, Kiaa0677
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 3A (EC 1.14.11.-) (Jumonji domain-containing protein 2A).