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Network neighborhood for query Sequence : M10L1_HUMAN

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M10L1_HUMAN
SwissProt Accessions	Q9BXT6, Q5TGD5, Q8NBD4, Q9NXW3, Q9UFB3, Q9UGX9	Gene names	MOV10L1
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

M10L1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BXT6, Q5TGD5, Q8NBD4, Q9NXW3, Q9UFB3, Q9UGX9	Gene names	MOV10L1
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1).

M10L1_MOUSE
θ value	0 (rank : 2)	NC score	0.980439 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	59	Shared Neighborhood Hits	24
SwissProt Accessions	Q99MV5, Q7TPA9, Q8C3W0, Q924C2	Gene names	Mov10l1, Champ
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase).

MOV10_HUMAN
θ value	2.79562e-118 (rank : 3)	NC score	0.903020 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

MOV10_MOUSE
θ value	2.89973e-107 (rank : 4)	NC score	0.899971 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	39	Shared Neighborhood Hits	21
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

CX048_HUMAN
θ value	4.38363e-63 (rank : 5)	NC score	0.651600 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WUE5, Q9NWY8	Gene names	CXorf48
Domain Architecture	No domain graphic available
Description	Protein CXorf48 (Tumor antigen BJ-HCC-20).

HELZ_HUMAN
θ value	2.75849e-49 (rank : 6)	NC score	0.774404 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

RENT1_MOUSE
θ value	6.37413e-38 (rank : 7)	NC score	0.765928 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	54	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

RENT1_HUMAN
θ value	8.32485e-38 (rank : 8)	NC score	0.765880 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

PR285_HUMAN
θ value	1.37539e-32 (rank : 9)	NC score	0.729842 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	63	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

SMBP2_MOUSE
θ value	4.14116e-29 (rank : 10)	NC score	0.713428 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	104	Shared Neighborhood Hits	19
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

SMBP2_HUMAN
θ value	2.05525e-28 (rank : 11)	NC score	0.722401 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	107	Shared Neighborhood Hits	19
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

SETX_HUMAN
θ value	1.42661e-21 (rank : 12)	NC score	0.628625 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	368	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

ZNFX1_HUMAN
θ value	2.28291e-11 (rank : 13)	NC score	0.421412 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	308	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_MOUSE
θ value	8.67504e-11 (rank : 14)	NC score	0.420480 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	407	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

AQR_HUMAN
θ value	2.88788e-06 (rank : 15)	NC score	0.386528 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

AQR_MOUSE
θ value	2.88788e-06 (rank : 16)	NC score	0.389054 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

DYHC_HUMAN
θ value	0.125558 (rank : 17)	NC score	0.050534 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	733	Shared Neighborhood Hits	13
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	0.125558 (rank : 18)	NC score	0.050577 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	729	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

RFC2_MOUSE
θ value	0.62314 (rank : 19)	NC score	0.053594 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	46	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WUK4	Gene names	Rfc2
Domain Architecture
Description	Replication factor C subunit 2 (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) (Activator 1 40 kDa subunit) (A1 40 kDa subunit).

MPP4_HUMAN
θ value	0.813845 (rank : 20)	NC score	0.022759 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	205	Shared Neighborhood Hits	4
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

RFC5_MOUSE
θ value	0.813845 (rank : 21)	NC score	0.090937 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	58	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC2_HUMAN
θ value	1.06291 (rank : 22)	NC score	0.052950 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	P35250, P32846, Q9BU93	Gene names	RFC2
Domain Architecture
Description	Replication factor C subunit 2 (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) (Activator 1 40 kDa subunit) (A1 40 kDa subunit).

RFC4_HUMAN
θ value	1.38821 (rank : 23)	NC score	0.080486 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	64	Shared Neighborhood Hits	15
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

RFC5_HUMAN
θ value	1.81305 (rank : 24)	NC score	0.084261 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	60	Shared Neighborhood Hits	15
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

MPP4_MOUSE
θ value	2.36792 (rank : 25)	NC score	0.018135 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	188	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

RFC4_MOUSE
θ value	2.36792 (rank : 26)	NC score	0.084057 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

TCPG_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.009673 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	P49368, Q5SZY1, Q9BR64	Gene names	CCT3, CCTG, TRIC5
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (hTRiC5).

CCAR1_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.021549 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	444	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

ATRX_MOUSE
θ value	4.03905 (rank : 29)	NC score	0.007126 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	682	Shared Neighborhood Hits	6
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

CCAR1_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.019966 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	414	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

DSRAD_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.010609 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	P55265, O15223, O43859, O43860, Q9BYM3, Q9BYM4	Gene names	ADAR, ADAR1, DSRAD, IFI4
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (136 kDa double-stranded RNA-binding protein) (P136) (K88DSRBP) (Interferon-inducible protein 4) (IFI-4 protein).

O10R2_HUMAN
θ value	5.27518 (rank : 32)	NC score	-0.001602 (rank : 37)
Query Neighborhood Hits	36	Target Neighborhood Hits	689	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NGX6, Q5VWM8, Q96R61	Gene names	OR10R2
Domain Architecture
Description	Olfactory receptor 10R2.

RBBP8_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.009430 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	476	Shared Neighborhood Hits	5
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

EPC2_HUMAN
θ value	8.99809 (rank : 34)	NC score	0.007458 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q52LR7, Q7L9J1, Q96RR7, Q9NUT8, Q9NVR1, Q9UFM9	Gene names	EPC2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

MLL3_HUMAN
θ value	8.99809 (rank : 35)	NC score	0.010653 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	1644	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

RAD17_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.018374 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	O75943, O75714, Q7Z3S4, Q9UNK7, Q9UNR7, Q9UNR8, Q9UPF5	Gene names	RAD17, R24L
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog).

RRP44_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.058011 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	35	Shared Neighborhood Hits	1
SwissProt Accessions	Q9Y2L1, Q5W0P7, Q5W0P8, Q658Z7, Q7Z481, Q8WWI2, Q9UG36	Gene names	DIS3, KIAA1008, RRP44
Domain Architecture
Description	Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Ribosomal RNA- processing protein 44) (DIS3 protein homolog).

Hits sorted by NC score

M10L1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	Q9BXT6, Q5TGD5, Q8NBD4, Q9NXW3, Q9UFB3, Q9UGX9	Gene names	MOV10L1
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1).

M10L1_MOUSE
NC score	0.980439 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	59	Shared Neighborhood Hits	24
SwissProt Accessions	Q99MV5, Q7TPA9, Q8C3W0, Q924C2	Gene names	Mov10l1, Champ
Domain Architecture
Description	Putative helicase Mov10l1 (EC 3.6.1.-) (Moloney leukemia virus 10-like protein 1) (MOV10-like 1) (Cardiac helicase activated by MEF2 protein) (Cardiac-specific RNA helicase).

MOV10_HUMAN
NC score	0.903020 (rank : 3)	θ value	2.79562e-118 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	Q9HCE1, Q8TEF0, Q9BSY3, Q9BUJ9	Gene names	MOV10, KIAA1631
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

MOV10_MOUSE
NC score	0.899971 (rank : 4)	θ value	2.89973e-107 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	39	Shared Neighborhood Hits	21
SwissProt Accessions	P23249, Q9DC64	Gene names	Mov10, Gb110
Domain Architecture
Description	Putative helicase MOV-10 (EC 3.6.1.-) (Moloney leukemia virus 10 protein).

HELZ_HUMAN
NC score	0.774404 (rank : 5)	θ value	2.75849e-49 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	198	Shared Neighborhood Hits	20
SwissProt Accessions	P42694	Gene names	HELZ, KIAA0054
Domain Architecture	No domain graphic available
Description	Probable helicase with zinc-finger domain (EC 3.6.1.-).

RENT1_MOUSE
NC score	0.765928 (rank : 6)	θ value	6.37413e-38 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	54	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EPU0, Q99PR4	Gene names	Upf1, Rent1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (mUpf1).

RENT1_HUMAN
NC score	0.765880 (rank : 7)	θ value	8.32485e-38 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q92900, O00239, O43343, Q86Z25, Q92842	Gene names	UPF1, KIAA0221, RENT1
Domain Architecture
Description	Regulator of nonsense transcripts 1 (EC 3.6.1.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up- frameshift suppressor 1 homolog) (hUpf1).

PR285_HUMAN
NC score	0.729842 (rank : 8)	θ value	1.37539e-32 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	63	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BYK8, Q3C2G2, Q4VXQ1, Q8TEF3, Q96ND3, Q9C094	Gene names	PRIC285, KIAA1769
Domain Architecture
Description	Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein (EC 3.6.1.-) (ATP-dependent helicase PRIC285) (PPAR-alpha- interacting complex protein 285) (PPAR-gamma DBD-interacting protein 1) (PDIP1).

SMBP2_HUMAN
NC score	0.722401 (rank : 9)	θ value	2.05525e-28 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	107	Shared Neighborhood Hits	19
SwissProt Accessions	P38935, Q00443, Q14177	Gene names	IGHMBP2, SMBP2, SMUBP2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Glial factor 1) (GF-1).

SMBP2_MOUSE
NC score	0.713428 (rank : 10)	θ value	4.14116e-29 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	104	Shared Neighborhood Hits	19
SwissProt Accessions	P40694	Gene names	Ighmbp2, Smbp-2, Smbp2
Domain Architecture
Description	DNA-binding protein SMUBP-2 (EC 3.6.1.-) (ATP-dependent helicase IGHMBP2) (Immunoglobulin mu-binding protein 2) (SMUBP-2) (Cardiac transcription factor 1) (CATF1).

CX048_HUMAN
NC score	0.651600 (rank : 11)	θ value	4.38363e-63 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WUE5, Q9NWY8	Gene names	CXorf48
Domain Architecture	No domain graphic available
Description	Protein CXorf48 (Tumor antigen BJ-HCC-20).

SETX_HUMAN
NC score	0.628625 (rank : 12)	θ value	1.42661e-21 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	368	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

ZNFX1_HUMAN
NC score	0.421412 (rank : 13)	θ value	2.28291e-11 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	308	Shared Neighborhood Hits	17
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_MOUSE
NC score	0.420480 (rank : 14)	θ value	8.67504e-11 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	407	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

AQR_MOUSE
NC score	0.389054 (rank : 15)	θ value	2.88788e-06 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	62	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CFQ3, P97871, Q3U9N1, Q3ULE8, Q80TX8	Gene names	Aqr, Kiaa0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius.

AQR_HUMAN
NC score	0.386528 (rank : 16)	θ value	2.88788e-06 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	O60306, Q2YDX9, Q6IRU8, Q6PIC8	Gene names	AQR, KIAA0560
Domain Architecture	No domain graphic available
Description	Intron-binding protein aquarius (Intron-binding protein of 160 kDa) (IBP160).

RFC5_MOUSE
NC score	0.090937 (rank : 17)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	58	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D0F6	Gene names	Rfc5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC5_HUMAN
NC score	0.084261 (rank : 18)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	60	Shared Neighborhood Hits	15
SwissProt Accessions	P40937	Gene names	RFC5
Domain Architecture
Description	Replication factor C subunit 5 (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36) (Activator 1 36 kDa subunit) (A1 36 kDa subunit).

RFC4_MOUSE
NC score	0.084057 (rank : 19)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	65	Shared Neighborhood Hits	15
SwissProt Accessions	Q99J62	Gene names	Rfc4
Domain Architecture	No domain graphic available
Description	Replication factor C subunit 4.

RFC4_HUMAN
NC score	0.080486 (rank : 20)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	64	Shared Neighborhood Hits	15
SwissProt Accessions	P35249, Q6FHX7	Gene names	RFC4
Domain Architecture
Description	Replication factor C subunit 4 (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37) (Activator 1 37 kDa subunit) (A1 37 kDa subunit).

RRP44_HUMAN
NC score	0.058011 (rank : 21)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	36	Target Neighborhood Hits	35	Shared Neighborhood Hits	1
SwissProt Accessions	Q9Y2L1, Q5W0P7, Q5W0P8, Q658Z7, Q7Z481, Q8WWI2, Q9UG36	Gene names	DIS3, KIAA1008, RRP44
Domain Architecture
Description	Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Ribosomal RNA- processing protein 44) (DIS3 protein homolog).

RFC2_MOUSE
NC score	0.053594 (rank : 22)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	46	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WUK4	Gene names	Rfc2
Domain Architecture
Description	Replication factor C subunit 2 (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) (Activator 1 40 kDa subunit) (A1 40 kDa subunit).

RFC2_HUMAN
NC score	0.052950 (rank : 23)	θ value	1.06291 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	46	Shared Neighborhood Hits	9
SwissProt Accessions	P35250, P32846, Q9BU93	Gene names	RFC2
Domain Architecture
Description	Replication factor C subunit 2 (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40) (Activator 1 40 kDa subunit) (A1 40 kDa subunit).

DYHC_MOUSE
NC score	0.050577 (rank : 24)	θ value	0.125558 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	729	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_HUMAN
NC score	0.050534 (rank : 25)	θ value	0.125558 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	733	Shared Neighborhood Hits	13
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

MPP4_HUMAN
NC score	0.022759 (rank : 26)	θ value	0.813845 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	205	Shared Neighborhood Hits	4
SwissProt Accessions	Q96JB8, Q6ZNH6, Q96Q43, Q96Q44	Gene names	MPP4, ALS2CR5, DLG6
Domain Architecture
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein).

CCAR1_HUMAN
NC score	0.021549 (rank : 27)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	444	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

CCAR1_MOUSE
NC score	0.019966 (rank : 28)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	414	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

RAD17_HUMAN
NC score	0.018374 (rank : 29)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	44	Shared Neighborhood Hits	8
SwissProt Accessions	O75943, O75714, Q7Z3S4, Q9UNK7, Q9UNR7, Q9UNR8, Q9UPF5	Gene names	RAD17, R24L
Domain Architecture	No domain graphic available
Description	Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog).

MPP4_MOUSE
NC score	0.018135 (rank : 30)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	188	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P7F1, Q8BTT3, Q8BXM5, Q920P7, Q920P8	Gene names	Mpp4, Dlg6
Domain Architecture	No domain graphic available
Description	MAGUK p55 subfamily member 4 (Discs large homolog 6) (MDLG6).

MLL3_HUMAN
NC score	0.010653 (rank : 31)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	1644	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

DSRAD_HUMAN
NC score	0.010609 (rank : 32)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	P55265, O15223, O43859, O43860, Q9BYM3, Q9BYM4	Gene names	ADAR, ADAR1, DSRAD, IFI4
Domain Architecture
Description	Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (136 kDa double-stranded RNA-binding protein) (P136) (K88DSRBP) (Interferon-inducible protein 4) (IFI-4 protein).

TCPG_HUMAN
NC score	0.009673 (rank : 33)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	P49368, Q5SZY1, Q9BR64	Gene names	CCT3, CCTG, TRIC5
Domain Architecture
Description	T-complex protein 1 subunit gamma (TCP-1-gamma) (CCT-gamma) (hTRiC5).

RBBP8_HUMAN
NC score	0.009430 (rank : 34)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	476	Shared Neighborhood Hits	5
SwissProt Accessions	Q99708, O75371	Gene names	RBBP8, CTIP
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 8 (RBBP-8) (CtBP-interacting protein) (CtIP) (Retinoblastoma-interacting protein and myosin-like) (RIM).

EPC2_HUMAN
NC score	0.007458 (rank : 35)	θ value	8.99809 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q52LR7, Q7L9J1, Q96RR7, Q9NUT8, Q9NVR1, Q9UFM9	Gene names	EPC2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

ATRX_MOUSE
NC score	0.007126 (rank : 36)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	682	Shared Neighborhood Hits	6
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

O10R2_HUMAN
NC score	-0.001602 (rank : 37)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	689	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NGX6, Q5VWM8, Q96R61	Gene names	OR10R2
Domain Architecture
Description	Olfactory receptor 10R2.