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Network neighborhood for query Sequence : EZH2_HUMAN

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EZH2_HUMAN
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EZH1_HUMAN
θ value	0 (rank : 1)	NC score	0.988594 (rank : 3)
Query Neighborhood Hits	84	Target Neighborhood Hits	121	Shared Neighborhood Hits	53
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
θ value	0 (rank : 2)	NC score	0.988470 (rank : 4)
Query Neighborhood Hits	84	Target Neighborhood Hits	126	Shared Neighborhood Hits	54
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH2_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	84	Target Neighborhood Hits	84	Shared Neighborhood Hits	84
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
θ value	0 (rank : 4)	NC score	0.999387 (rank : 2)
Query Neighborhood Hits	84	Target Neighborhood Hits	86	Shared Neighborhood Hits	80
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

HRX_HUMAN
θ value	3.17815e-21 (rank : 5)	NC score	0.558268 (rank : 15)
Query Neighborhood Hits	84	Target Neighborhood Hits	825	Shared Neighborhood Hits	32
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

NSD1_MOUSE
θ value	2.06002e-20 (rank : 6)	NC score	0.565590 (rank : 14)
Query Neighborhood Hits	84	Target Neighborhood Hits	472	Shared Neighborhood Hits	32
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

SUV91_HUMAN
θ value	2.06002e-20 (rank : 7)	NC score	0.701618 (rank : 5)
Query Neighborhood Hits	84	Target Neighborhood Hits	63	Shared Neighborhood Hits	28
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

SUV91_MOUSE
θ value	2.06002e-20 (rank : 8)	NC score	0.695477 (rank : 6)
Query Neighborhood Hits	84	Target Neighborhood Hits	69	Shared Neighborhood Hits	28
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

NSD1_HUMAN
θ value	2.69047e-20 (rank : 9)	NC score	0.568112 (rank : 13)
Query Neighborhood Hits	84	Target Neighborhood Hits	427	Shared Neighborhood Hits	28
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

SETD2_HUMAN
θ value	2.69047e-20 (rank : 10)	NC score	0.656445 (rank : 9)
Query Neighborhood Hits	84	Target Neighborhood Hits	412	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SET1A_HUMAN
θ value	3.51386e-20 (rank : 11)	NC score	0.614956 (rank : 10)
Query Neighborhood Hits	84	Target Neighborhood Hits	690	Shared Neighborhood Hits	33
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SUV92_MOUSE
θ value	2.97466e-19 (rank : 12)	NC score	0.685381 (rank : 8)
Query Neighborhood Hits	84	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV92_HUMAN
θ value	3.88503e-19 (rank : 13)	NC score	0.691368 (rank : 7)
Query Neighborhood Hits	84	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

MLL4_HUMAN
θ value	5.07402e-19 (rank : 14)	NC score	0.539904 (rank : 16)
Query Neighborhood Hits	84	Target Neighborhood Hits	722	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MLL3_HUMAN
θ value	8.65492e-19 (rank : 15)	NC score	0.415554 (rank : 22)
Query Neighborhood Hits	84	Target Neighborhood Hits	1644	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL3_MOUSE
θ value	8.65492e-19 (rank : 16)	NC score	0.436981 (rank : 20)
Query Neighborhood Hits	84	Target Neighborhood Hits	1399	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL2_HUMAN
θ value	2.5182e-18 (rank : 17)	NC score	0.424426 (rank : 21)
Query Neighborhood Hits	84	Target Neighborhood Hits	1788	Shared Neighborhood Hits	48
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

EHMT2_MOUSE
θ value	7.32683e-18 (rank : 18)	NC score	0.341998 (rank : 24)
Query Neighborhood Hits	84	Target Neighborhood Hits	750	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_HUMAN
θ value	1.63225e-17 (rank : 19)	NC score	0.344295 (rank : 23)
Query Neighborhood Hits	84	Target Neighborhood Hits	498	Shared Neighborhood Hits	35
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT1_HUMAN
θ value	2.60593e-15 (rank : 20)	NC score	0.333982 (rank : 25)
Query Neighborhood Hits	84	Target Neighborhood Hits	417	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

SETD8_HUMAN
θ value	3.29651e-10 (rank : 21)	NC score	0.612180 (rank : 11)
Query Neighborhood Hits	84	Target Neighborhood Hits	114	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SETD8_MOUSE
θ value	3.29651e-10 (rank : 22)	NC score	0.611189 (rank : 12)
Query Neighborhood Hits	84	Target Neighborhood Hits	131	Shared Neighborhood Hits	24
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SETB1_MOUSE
θ value	6.43352e-06 (rank : 23)	NC score	0.469258 (rank : 18)
Query Neighborhood Hits	84	Target Neighborhood Hits	150	Shared Neighborhood Hits	26
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB1_HUMAN
θ value	1.09739e-05 (rank : 24)	NC score	0.464149 (rank : 19)
Query Neighborhood Hits	84	Target Neighborhood Hits	141	Shared Neighborhood Hits	25
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB2_HUMAN
θ value	5.44631e-05 (rank : 25)	NC score	0.504110 (rank : 17)
Query Neighborhood Hits	84	Target Neighborhood Hits	62	Shared Neighborhood Hits	28
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

SETD7_MOUSE
θ value	0.0113563 (rank : 26)	NC score	0.196432 (rank : 26)
Query Neighborhood Hits	84	Target Neighborhood Hits	39	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VHL1	Gene names	Setd7, Set7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7).

SETD7_HUMAN
θ value	0.0252991 (rank : 27)	NC score	0.190698 (rank : 27)
Query Neighborhood Hits	84	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WTS6, Q9C0E6	Gene names	SETD7, KIAA1717, SET7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7) (Set9) (SET7/9).

MCSP_MOUSE
θ value	0.125558 (rank : 28)	NC score	0.160192 (rank : 28)
Query Neighborhood Hits	84	Target Neighborhood Hits	108	Shared Neighborhood Hits	17
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

KRA58_HUMAN
θ value	0.21417 (rank : 29)	NC score	0.093920 (rank : 31)
Query Neighborhood Hits	84	Target Neighborhood Hits	324	Shared Neighborhood Hits	24
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

LR37A_HUMAN
θ value	0.21417 (rank : 30)	NC score	0.049430 (rank : 79)
Query Neighborhood Hits	84	Target Neighborhood Hits	720	Shared Neighborhood Hits	13
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

NOTC2_HUMAN
θ value	0.365318 (rank : 31)	NC score	0.040558 (rank : 87)
Query Neighborhood Hits	84	Target Neighborhood Hits	1113	Shared Neighborhood Hits	44
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CENB5_HUMAN
θ value	0.47712 (rank : 32)	NC score	0.035757 (rank : 92)
Query Neighborhood Hits	84	Target Neighborhood Hits	395	Shared Neighborhood Hits	13
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

KR511_HUMAN
θ value	0.47712 (rank : 33)	NC score	0.088388 (rank : 32)
Query Neighborhood Hits	84	Target Neighborhood Hits	231	Shared Neighborhood Hits	22
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA24_HUMAN
θ value	0.47712 (rank : 34)	NC score	0.066491 (rank : 46)
Query Neighborhood Hits	84	Target Neighborhood Hits	192	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

ITB1_HUMAN
θ value	0.62314 (rank : 35)	NC score	0.036893 (rank : 90)
Query Neighborhood Hits	84	Target Neighborhood Hits	298	Shared Neighborhood Hits	28
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

KIF4A_HUMAN
θ value	0.62314 (rank : 36)	NC score	0.017989 (rank : 109)
Query Neighborhood Hits	84	Target Neighborhood Hits	1159	Shared Neighborhood Hits	20
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

KRA53_HUMAN
θ value	0.62314 (rank : 37)	NC score	0.076953 (rank : 41)
Query Neighborhood Hits	84	Target Neighborhood Hits	331	Shared Neighborhood Hits	25
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA57_HUMAN
θ value	0.62314 (rank : 38)	NC score	0.067761 (rank : 45)
Query Neighborhood Hits	84	Target Neighborhood Hits	269	Shared Neighborhood Hits	23
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

NPBL_MOUSE
θ value	0.62314 (rank : 39)	NC score	0.045007 (rank : 84)
Query Neighborhood Hits	84	Target Neighborhood Hits	1041	Shared Neighborhood Hits	18
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

DYNA_MOUSE
θ value	1.06291 (rank : 40)	NC score	0.013834 (rank : 114)
Query Neighborhood Hits	84	Target Neighborhood Hits	1084	Shared Neighborhood Hits	9
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

IF4G3_MOUSE
θ value	1.06291 (rank : 41)	NC score	0.025900 (rank : 105)
Query Neighborhood Hits	84	Target Neighborhood Hits	279	Shared Neighborhood Hits	7
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

ITB1_MOUSE
θ value	1.06291 (rank : 42)	NC score	0.029234 (rank : 100)
Query Neighborhood Hits	84	Target Neighborhood Hits	283	Shared Neighborhood Hits	25
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

NOTC2_MOUSE
θ value	1.06291 (rank : 43)	NC score	0.036583 (rank : 91)
Query Neighborhood Hits	84	Target Neighborhood Hits	1069	Shared Neighborhood Hits	39
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

SSPO_MOUSE
θ value	1.38821 (rank : 44)	NC score	0.031244 (rank : 95)
Query Neighborhood Hits	84	Target Neighborhood Hits	800	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

STAB1_HUMAN
θ value	1.38821 (rank : 45)	NC score	0.020825 (rank : 106)
Query Neighborhood Hits	84	Target Neighborhood Hits	546	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

ZNFX1_MOUSE
θ value	1.38821 (rank : 46)	NC score	0.047446 (rank : 82)
Query Neighborhood Hits	84	Target Neighborhood Hits	407	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ATS13_MOUSE
θ value	1.81305 (rank : 47)	NC score	0.013518 (rank : 115)
Query Neighborhood Hits	84	Target Neighborhood Hits	227	Shared Neighborhood Hits	11
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

NCOR2_MOUSE
θ value	1.81305 (rank : 48)	NC score	0.041615 (rank : 85)
Query Neighborhood Hits	84	Target Neighborhood Hits	790	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

NOTC1_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.031944 (rank : 94)
Query Neighborhood Hits	84	Target Neighborhood Hits	906	Shared Neighborhood Hits	32
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

RCOR3_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.030285 (rank : 99)
Query Neighborhood Hits	84	Target Neighborhood Hits	161	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

ZNFX1_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.045981 (rank : 83)
Query Neighborhood Hits	84	Target Neighborhood Hits	308	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

MT2_MOUSE
θ value	3.0926 (rank : 52)	NC score	0.047640 (rank : 81)
Query Neighborhood Hits	84	Target Neighborhood Hits	81	Shared Neighborhood Hits	12
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

ATL2_MOUSE
θ value	4.03905 (rank : 53)	NC score	0.011752 (rank : 116)
Query Neighborhood Hits	84	Target Neighborhood Hits	137	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

DYNA_HUMAN
θ value	4.03905 (rank : 54)	NC score	0.015647 (rank : 112)
Query Neighborhood Hits	84	Target Neighborhood Hits	1194	Shared Neighborhood Hits	14
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

KRA52_HUMAN
θ value	4.03905 (rank : 55)	NC score	0.031094 (rank : 96)
Query Neighborhood Hits	84	Target Neighborhood Hits	236	Shared Neighborhood Hits	20
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

MEGF6_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.019911 (rank : 107)
Query Neighborhood Hits	84	Target Neighborhood Hits	671	Shared Neighborhood Hits	32
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

NCOR2_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.047885 (rank : 80)
Query Neighborhood Hits	84	Target Neighborhood Hits	870	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

OXRP_HUMAN
θ value	4.03905 (rank : 58)	NC score	0.017869 (rank : 110)
Query Neighborhood Hits	84	Target Neighborhood Hits	544	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PGBM_MOUSE
θ value	4.03905 (rank : 59)	NC score	0.007592 (rank : 120)
Query Neighborhood Hits	84	Target Neighborhood Hits	1073	Shared Neighborhood Hits	26
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ZAN_MOUSE
θ value	4.03905 (rank : 60)	NC score	0.036993 (rank : 89)
Query Neighborhood Hits	84	Target Neighborhood Hits	808	Shared Neighborhood Hits	38
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

FGD4_HUMAN
θ value	5.27518 (rank : 61)	NC score	0.005645 (rank : 125)
Query Neighborhood Hits	84	Target Neighborhood Hits	219	Shared Neighborhood Hits	4
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

KRA59_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.059906 (rank : 58)
Query Neighborhood Hits	84	Target Neighborhood Hits	310	Shared Neighborhood Hits	28
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

RCOR2_HUMAN
θ value	5.27518 (rank : 63)	NC score	0.032372 (rank : 93)
Query Neighborhood Hits	84	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

RCOR2_MOUSE
θ value	5.27518 (rank : 64)	NC score	0.037295 (rank : 88)
Query Neighborhood Hits	84	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

UBP25_MOUSE
θ value	5.27518 (rank : 65)	NC score	0.007612 (rank : 119)
Query Neighborhood Hits	84	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

VEGFC_MOUSE
θ value	5.27518 (rank : 66)	NC score	0.027175 (rank : 104)
Query Neighborhood Hits	84	Target Neighborhood Hits	119	Shared Neighborhood Hits	14
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

ALBU_MOUSE
θ value	6.88961 (rank : 67)	NC score	0.007006 (rank : 121)
Query Neighborhood Hits	84	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	P07724, Q61802	Gene names	Alb, Alb-1, Alb1
Domain Architecture
Description	Serum albumin precursor.

GPC6A_MOUSE
θ value	6.88961 (rank : 68)	NC score	0.006242 (rank : 123)
Query Neighborhood Hits	84	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4Z6, Q5DK51, Q5DK52	Gene names	Gprc6a
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor.

KIF4A_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.010392 (rank : 118)
Query Neighborhood Hits	84	Target Neighborhood Hits	1033	Shared Neighborhood Hits	19
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

KR105_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.041224 (rank : 86)
Query Neighborhood Hits	84	Target Neighborhood Hits	271	Shared Neighborhood Hits	28
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

MYSM1_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.030674 (rank : 97)
Query Neighborhood Hits	84	Target Neighborhood Hits	73	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VVJ2, Q7Z3G8, Q96PX3	Gene names	MYSM1, KIAA1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

PKHA6_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.017578 (rank : 111)
Query Neighborhood Hits	84	Target Neighborhood Hits	556	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SMYD3_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.062266 (rank : 56)
Query Neighborhood Hits	84	Target Neighborhood Hits	56	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

TGON1_MOUSE
θ value	6.88961 (rank : 74)	NC score	0.019717 (rank : 108)
Query Neighborhood Hits	84	Target Neighborhood Hits	243	Shared Neighborhood Hits	8
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

UB7I4_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.011299 (rank : 117)
Query Neighborhood Hits	84	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

VWF_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.028645 (rank : 102)
Query Neighborhood Hits	84	Target Neighborhood Hits	381	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

BAI3_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.005793 (rank : 124)
Query Neighborhood Hits	84	Target Neighborhood Hits	246	Shared Neighborhood Hits	9
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

CJ012_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.029102 (rank : 101)
Query Neighborhood Hits	84	Target Neighborhood Hits	467	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

CRIM1_HUMAN
θ value	8.99809 (rank : 79)	NC score	0.030425 (rank : 98)
Query Neighborhood Hits	84	Target Neighborhood Hits	362	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

DLL1_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.015560 (rank : 113)
Query Neighborhood Hits	84	Target Neighborhood Hits	455	Shared Neighborhood Hits	29
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

EGFR_HUMAN
θ value	8.99809 (rank : 81)	NC score	-0.001354 (rank : 127)
Query Neighborhood Hits	84	Target Neighborhood Hits	939	Shared Neighborhood Hits	13
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).

GP116_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.006947 (rank : 122)
Query Neighborhood Hits	84	Target Neighborhood Hits	167	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

MIB1_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.028404 (rank : 103)
Query Neighborhood Hits	84	Target Neighborhood Hits	470	Shared Neighborhood Hits	12
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

TIE2_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.000123 (rank : 126)
Query Neighborhood Hits	84	Target Neighborhood Hits	1204	Shared Neighborhood Hits	19
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

AIRE_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.064092 (rank : 55)
Query Neighborhood Hits	84	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.066341 (rank : 48)
Query Neighborhood Hits	84	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

CBX1_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.057709 (rank : 64)
Query Neighborhood Hits	84	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.057709 (rank : 65)
Query Neighborhood Hits	84	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX3_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.059222 (rank : 63)
Query Neighborhood Hits	84	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX3_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.059807 (rank : 59)
Query Neighborhood Hits	84	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CBX5_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.054797 (rank : 71)
Query Neighborhood Hits	84	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.054493 (rank : 74)
Query Neighborhood Hits	84	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

DPF1_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.074748 (rank : 42)
Query Neighborhood Hits	84	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

DPF1_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.066159 (rank : 49)
Query Neighborhood Hits	84	Target Neighborhood Hits	491	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

K1333_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.065162 (rank : 53)
Query Neighborhood Hits	84	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

K1333_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.065221 (rank : 52)
Query Neighborhood Hits	84	Target Neighborhood Hits	53	Shared Neighborhood Hits	7
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

LCE1D_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.055227 (rank : 69)
Query Neighborhood Hits	84	Target Neighborhood Hits	44	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

LCE1E_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.054141 (rank : 75)
Query Neighborhood Hits	84	Target Neighborhood Hits	53	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

MYST3_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.055510 (rank : 68)
Query Neighborhood Hits	84	Target Neighborhood Hits	772	Shared Neighborhood Hits	14
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST3_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.057004 (rank : 66)
Query Neighborhood Hits	84	Target Neighborhood Hits	688	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

MYST4_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.065687 (rank : 50)
Query Neighborhood Hits	84	Target Neighborhood Hits	671	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

MYST4_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.059233 (rank : 62)
Query Neighborhood Hits	84	Target Neighborhood Hits	416	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

PF21A_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.059593 (rank : 60)
Query Neighborhood Hits	84	Target Neighborhood Hits	303	Shared Neighborhood Hits	9
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.059281 (rank : 61)
Query Neighborhood Hits	84	Target Neighborhood Hits	285	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21B_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.050131 (rank : 78)
Query Neighborhood Hits	84	Target Neighborhood Hits	197	Shared Neighborhood Hits	6
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.055847 (rank : 67)
Query Neighborhood Hits	84	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF10_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.084335 (rank : 36)
Query Neighborhood Hits	84	Target Neighborhood Hits	151	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.082816 (rank : 37)
Query Neighborhood Hits	84	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF11_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.114498 (rank : 30)
Query Neighborhood Hits	84	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

PHF12_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.054778 (rank : 72)
Query Neighborhood Hits	84	Target Neighborhood Hits	174	Shared Neighborhood Hits	8
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.054828 (rank : 70)
Query Neighborhood Hits	84	Target Neighborhood Hits	172	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF6_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.087525 (rank : 33)
Query Neighborhood Hits	84	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF6_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.084980 (rank : 35)
Query Neighborhood Hits	84	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

PHF7_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.071178 (rank : 44)
Query Neighborhood Hits	84	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PHF7_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.066462 (rank : 47)
Query Neighborhood Hits	84	Target Neighborhood Hits	65	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PTMA_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.114519 (rank : 29)
Query Neighborhood Hits	84	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

PTMA_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.080314 (rank : 38)
Query Neighborhood Hits	84	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

PYGO2_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.050458 (rank : 77)
Query Neighborhood Hits	84	Target Neighborhood Hits	189	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

RAI1_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.078618 (rank : 40)
Query Neighborhood Hits	84	Target Neighborhood Hits	360	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RAI1_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.085103 (rank : 34)
Query Neighborhood Hits	84	Target Neighborhood Hits	344	Shared Neighborhood Hits	13
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

REQU_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.065408 (rank : 51)
Query Neighborhood Hits	84	Target Neighborhood Hits	523	Shared Neighborhood Hits	7
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

REQU_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.064933 (rank : 54)
Query Neighborhood Hits	84	Target Neighborhood Hits	519	Shared Neighborhood Hits	7
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

SMYD3_MOUSE
θ value	θ > 10 (rank : 123)	NC score	0.060042 (rank : 57)
Query Neighborhood Hits	84	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CWR2, Q6P7V6, Q8BG90	Gene names	Smyd3, Zmynd1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

TCF20_HUMAN
θ value	θ > 10 (rank : 124)	NC score	0.078690 (rank : 39)
Query Neighborhood Hits	84	Target Neighborhood Hits	323	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TCF20_MOUSE
θ value	θ > 10 (rank : 125)	NC score	0.074307 (rank : 43)
Query Neighborhood Hits	84	Target Neighborhood Hits	396	Shared Neighborhood Hits	13
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

UHRF1_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.051107 (rank : 76)
Query Neighborhood Hits	84	Target Neighborhood Hits	272	Shared Neighborhood Hits	7
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

UHRF1_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.054607 (rank : 73)
Query Neighborhood Hits	84	Target Neighborhood Hits	278	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

Hits sorted by NC score

EZH2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	84	Target Neighborhood Hits	84	Shared Neighborhood Hits	84
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
NC score	0.999387 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	84	Target Neighborhood Hits	86	Shared Neighborhood Hits	80
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH1_HUMAN
NC score	0.988594 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	84	Target Neighborhood Hits	121	Shared Neighborhood Hits	53
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
NC score	0.988470 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	84	Target Neighborhood Hits	126	Shared Neighborhood Hits	54
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

SUV91_HUMAN
NC score	0.701618 (rank : 5)	θ value	2.06002e-20 (rank : 7)
Query Neighborhood Hits	84	Target Neighborhood Hits	63	Shared Neighborhood Hits	28
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

SUV91_MOUSE
NC score	0.695477 (rank : 6)	θ value	2.06002e-20 (rank : 8)
Query Neighborhood Hits	84	Target Neighborhood Hits	69	Shared Neighborhood Hits	28
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SUV92_HUMAN
NC score	0.691368 (rank : 7)	θ value	3.88503e-19 (rank : 13)
Query Neighborhood Hits	84	Target Neighborhood Hits	54	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV92_MOUSE
NC score	0.685381 (rank : 8)	θ value	2.97466e-19 (rank : 12)
Query Neighborhood Hits	84	Target Neighborhood Hits	59	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SETD2_HUMAN
NC score	0.656445 (rank : 9)	θ value	2.69047e-20 (rank : 10)
Query Neighborhood Hits	84	Target Neighborhood Hits	412	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SET1A_HUMAN
NC score	0.614956 (rank : 10)	θ value	3.51386e-20 (rank : 11)
Query Neighborhood Hits	84	Target Neighborhood Hits	690	Shared Neighborhood Hits	33
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

SETD8_HUMAN
NC score	0.612180 (rank : 11)	θ value	3.29651e-10 (rank : 21)
Query Neighborhood Hits	84	Target Neighborhood Hits	114	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SETD8_MOUSE
NC score	0.611189 (rank : 12)	θ value	3.29651e-10 (rank : 22)
Query Neighborhood Hits	84	Target Neighborhood Hits	131	Shared Neighborhood Hits	24
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

NSD1_HUMAN
NC score	0.568112 (rank : 13)	θ value	2.69047e-20 (rank : 9)
Query Neighborhood Hits	84	Target Neighborhood Hits	427	Shared Neighborhood Hits	28
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
NC score	0.565590 (rank : 14)	θ value	2.06002e-20 (rank : 6)
Query Neighborhood Hits	84	Target Neighborhood Hits	472	Shared Neighborhood Hits	32
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

HRX_HUMAN
NC score	0.558268 (rank : 15)	θ value	3.17815e-21 (rank : 5)
Query Neighborhood Hits	84	Target Neighborhood Hits	825	Shared Neighborhood Hits	32
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MLL4_HUMAN
NC score	0.539904 (rank : 16)	θ value	5.07402e-19 (rank : 14)
Query Neighborhood Hits	84	Target Neighborhood Hits	722	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SETB2_HUMAN
NC score	0.504110 (rank : 17)	θ value	5.44631e-05 (rank : 25)
Query Neighborhood Hits	84	Target Neighborhood Hits	62	Shared Neighborhood Hits	28
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

SETB1_MOUSE
NC score	0.469258 (rank : 18)	θ value	6.43352e-06 (rank : 23)
Query Neighborhood Hits	84	Target Neighborhood Hits	150	Shared Neighborhood Hits	26
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB1_HUMAN
NC score	0.464149 (rank : 19)	θ value	1.09739e-05 (rank : 24)
Query Neighborhood Hits	84	Target Neighborhood Hits	141	Shared Neighborhood Hits	25
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

MLL3_MOUSE
NC score	0.436981 (rank : 20)	θ value	8.65492e-19 (rank : 16)
Query Neighborhood Hits	84	Target Neighborhood Hits	1399	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL2_HUMAN
NC score	0.424426 (rank : 21)	θ value	2.5182e-18 (rank : 17)
Query Neighborhood Hits	84	Target Neighborhood Hits	1788	Shared Neighborhood Hits	48
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_HUMAN
NC score	0.415554 (rank : 22)	θ value	8.65492e-19 (rank : 15)
Query Neighborhood Hits	84	Target Neighborhood Hits	1644	Shared Neighborhood Hits	49
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

EHMT2_HUMAN
NC score	0.344295 (rank : 23)	θ value	1.63225e-17 (rank : 19)
Query Neighborhood Hits	84	Target Neighborhood Hits	498	Shared Neighborhood Hits	35
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
NC score	0.341998 (rank : 24)	θ value	7.32683e-18 (rank : 18)
Query Neighborhood Hits	84	Target Neighborhood Hits	750	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT1_HUMAN
NC score	0.333982 (rank : 25)	θ value	2.60593e-15 (rank : 20)
Query Neighborhood Hits	84	Target Neighborhood Hits	417	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

SETD7_MOUSE
NC score	0.196432 (rank : 26)	θ value	0.0113563 (rank : 26)
Query Neighborhood Hits	84	Target Neighborhood Hits	39	Shared Neighborhood Hits	14
SwissProt Accessions	Q8VHL1	Gene names	Setd7, Set7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7).

SETD7_HUMAN
NC score	0.190698 (rank : 27)	θ value	0.0252991 (rank : 27)
Query Neighborhood Hits	84	Target Neighborhood Hits	37	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WTS6, Q9C0E6	Gene names	SETD7, KIAA1717, SET7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7) (Set9) (SET7/9).

MCSP_MOUSE
NC score	0.160192 (rank : 28)	θ value	0.125558 (rank : 28)
Query Neighborhood Hits	84	Target Neighborhood Hits	108	Shared Neighborhood Hits	17
SwissProt Accessions	P15265, O70613, Q6P8N3	Gene names	Smcp, Mcs, Mcsp
Domain Architecture	No domain graphic available
Description	Sperm mitochondrial-associated cysteine-rich protein.

PTMA_HUMAN
NC score	0.114519 (rank : 29)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	84	Target Neighborhood Hits	88	Shared Neighborhood Hits	4
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

PHF11_HUMAN
NC score	0.114498 (rank : 30)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	84	Target Neighborhood Hits	42	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

KRA58_HUMAN
NC score	0.093920 (rank : 31)	θ value	0.21417 (rank : 29)
Query Neighborhood Hits	84	Target Neighborhood Hits	324	Shared Neighborhood Hits	24
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KR511_HUMAN
NC score	0.088388 (rank : 32)	θ value	0.47712 (rank : 33)
Query Neighborhood Hits	84	Target Neighborhood Hits	231	Shared Neighborhood Hits	22
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

PHF6_HUMAN
NC score	0.087525 (rank : 33)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	84	Target Neighborhood Hits	37	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

RAI1_MOUSE
NC score	0.085103 (rank : 34)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	84	Target Neighborhood Hits	344	Shared Neighborhood Hits	13
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

PHF6_MOUSE
NC score	0.084980 (rank : 35)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	84	Target Neighborhood Hits	39	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

PHF10_HUMAN
NC score	0.084335 (rank : 36)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	84	Target Neighborhood Hits	151	Shared Neighborhood Hits	8
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
NC score	0.082816 (rank : 37)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	84	Target Neighborhood Hits	131	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PTMA_MOUSE
NC score	0.080314 (rank : 38)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	84	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

TCF20_HUMAN
NC score	0.078690 (rank : 39)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	84	Target Neighborhood Hits	323	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

RAI1_HUMAN
NC score	0.078618 (rank : 40)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	84	Target Neighborhood Hits	360	Shared Neighborhood Hits	12
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

KRA53_HUMAN
NC score	0.076953 (rank : 41)	θ value	0.62314 (rank : 37)
Query Neighborhood Hits	84	Target Neighborhood Hits	331	Shared Neighborhood Hits	25
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

DPF1_HUMAN
NC score	0.074748 (rank : 42)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	84	Target Neighborhood Hits	136	Shared Neighborhood Hits	7
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

TCF20_MOUSE
NC score	0.074307 (rank : 43)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	84	Target Neighborhood Hits	396	Shared Neighborhood Hits	13
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

PHF7_HUMAN
NC score	0.071178 (rank : 44)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	84	Target Neighborhood Hits	71	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

KRA57_HUMAN
NC score	0.067761 (rank : 45)	θ value	0.62314 (rank : 38)
Query Neighborhood Hits	84	Target Neighborhood Hits	269	Shared Neighborhood Hits	23
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA24_HUMAN
NC score	0.066491 (rank : 46)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	84	Target Neighborhood Hits	192	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BYR9, Q495J2	Gene names	KRTAP2-4, KAP2.4, KRTAP2.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 2-4 (Keratin-associated protein 2.4) (High sulfur keratin-associated protein 2.4).

PHF7_MOUSE
NC score	0.066462 (rank : 47)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	84	Target Neighborhood Hits	65	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DAG9, Q6PG81	Gene names	Phf7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

AIRE_MOUSE
NC score	0.066341 (rank : 48)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	84	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

DPF1_MOUSE
NC score	0.066159 (rank : 49)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	84	Target Neighborhood Hits	491	Shared Neighborhood Hits	8
SwissProt Accessions	Q9QX66, Q9QX65, Q9QYA4	Gene names	Dpf1, Neud4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

MYST4_HUMAN
NC score	0.065687 (rank : 50)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	84	Target Neighborhood Hits	671	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

REQU_HUMAN
NC score	0.065408 (rank : 51)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	84	Target Neighborhood Hits	523	Shared Neighborhood Hits	7
SwissProt Accessions	Q92785	Gene names	DPF2, REQ, UBID4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

K1333_MOUSE
NC score	0.065221 (rank : 52)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	84	Target Neighborhood Hits	53	Shared Neighborhood Hits	7
SwissProt Accessions	Q5RJY2, Q6ZPT7, Q8BNA4	Gene names	Kiaa1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

K1333_HUMAN
NC score	0.065162 (rank : 53)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	84	Target Neighborhood Hits	50	Shared Neighborhood Hits	5
SwissProt Accessions	Q7L622, Q9BVR2, Q9H9E9, Q9NXC0, Q9P2L3	Gene names	KIAA1333
Domain Architecture	No domain graphic available
Description	Protein KIAA1333 (EC 6.3.2.-).

REQU_MOUSE
NC score	0.064933 (rank : 54)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	84	Target Neighborhood Hits	519	Shared Neighborhood Hits	7
SwissProt Accessions	Q61103, Q3UNP5, Q60663, Q9QYA3	Gene names	Dpf2, Req, Ubid4
Domain Architecture
Description	Zinc-finger protein ubi-d4 (Requiem) (Apoptosis response zinc finger protein) (D4, zinc and double PHD fingers family 2).

AIRE_HUMAN
NC score	0.064092 (rank : 55)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	84	Target Neighborhood Hits	144	Shared Neighborhood Hits	7
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

SMYD3_HUMAN
NC score	0.062266 (rank : 56)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	84	Target Neighborhood Hits	56	Shared Neighborhood Hits	19
SwissProt Accessions	Q9H7B4, Q86TL8, Q8N5Z6, Q96AI5	Gene names	SMYD3, ZMYND1, ZNFN3A1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

SMYD3_MOUSE
NC score	0.060042 (rank : 57)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	84	Target Neighborhood Hits	51	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CWR2, Q6P7V6, Q8BG90	Gene names	Smyd3, Zmynd1
Domain Architecture
Description	SET and MYND domain-containing protein 3 (EC 2.1.1.43) (Zinc finger MYND domain-containing protein 1).

KRA59_HUMAN
NC score	0.059906 (rank : 58)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	84	Target Neighborhood Hits	310	Shared Neighborhood Hits	28
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

CBX3_MOUSE
NC score	0.059807 (rank : 59)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	84	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

PF21A_HUMAN
NC score	0.059593 (rank : 60)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	84	Target Neighborhood Hits	303	Shared Neighborhood Hits	9
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
NC score	0.059281 (rank : 61)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	84	Target Neighborhood Hits	285	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

MYST4_MOUSE
NC score	0.059233 (rank : 62)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	84	Target Neighborhood Hits	416	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BRB7, Q7TNW5, Q8BG35, Q8C441, Q9JKX5	Gene names	Myst4
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Querkopf protein).

CBX3_HUMAN
NC score	0.059222 (rank : 63)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	84	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX1_HUMAN
NC score	0.057709 (rank : 64)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	84	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.057709 (rank : 65)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	84	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

MYST3_MOUSE
NC score	0.057004 (rank : 66)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	84	Target Neighborhood Hits	688	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

PF21B_MOUSE
NC score	0.055847 (rank : 67)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	84	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

MYST3_HUMAN
NC score	0.055510 (rank : 68)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	84	Target Neighborhood Hits	772	Shared Neighborhood Hits	14
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

LCE1D_HUMAN
NC score	0.055227 (rank : 69)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	84	Target Neighborhood Hits	44	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T752	Gene names	LCE1D, LEP4
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1D (Late envelope protein 4).

PHF12_MOUSE
NC score	0.054828 (rank : 70)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	84	Target Neighborhood Hits	172	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

CBX5_HUMAN
NC score	0.054797 (rank : 71)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	84	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

PHF12_HUMAN
NC score	0.054778 (rank : 72)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	84	Target Neighborhood Hits	174	Shared Neighborhood Hits	8
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

UHRF1_MOUSE
NC score	0.054607 (rank : 73)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	84	Target Neighborhood Hits	278	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VDF2, Q8C6F1, Q8VIA1, Q9Z1H6	Gene names	Uhrf1, Np95
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Nuclear zinc finger protein Np95) (Nuclear protein 95).

CBX5_MOUSE
NC score	0.054493 (rank : 74)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	84	Target Neighborhood Hits	67	Shared Neighborhood Hits	6
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

LCE1E_HUMAN
NC score	0.054141 (rank : 75)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	84	Target Neighborhood Hits	53	Shared Neighborhood Hits	13
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

UHRF1_HUMAN
NC score	0.051107 (rank : 76)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	84	Target Neighborhood Hits	272	Shared Neighborhood Hits	7
SwissProt Accessions	Q96T88, Q8J022, Q9H6S6, Q9P115, Q9P1U7	Gene names	UHRF1, ICBP90, NP95, RNF106
Domain Architecture	No domain graphic available
Description	Ubiquitin-like PHD and RING finger domain-containing protein 1 (EC 6.3.2.-) (Ubiquitin-like-containing PHD and RING finger domains protein 1) (Inverted CCAAT box-binding protein of 90 kDa) (Transcription factor ICBP90) (Nuclear zinc finger protein Np95) (Nuclear protein 95) (HuNp95) (RING finger protein 106).

PYGO2_HUMAN
NC score	0.050458 (rank : 77)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	84	Target Neighborhood Hits	189	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

PF21B_HUMAN
NC score	0.050131 (rank : 78)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	84	Target Neighborhood Hits	197	Shared Neighborhood Hits	6
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

LR37A_HUMAN
NC score	0.049430 (rank : 79)	θ value	0.21417 (rank : 30)
Query Neighborhood Hits	84	Target Neighborhood Hits	720	Shared Neighborhood Hits	13
SwissProt Accessions	O60309, Q49A01, Q49A80, Q8NB33	Gene names	LRRC37A, KIAA0563
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37A.

NCOR2_HUMAN
NC score	0.047885 (rank : 80)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	84	Target Neighborhood Hits	870	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

MT2_MOUSE
NC score	0.047640 (rank : 81)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	84	Target Neighborhood Hits	81	Shared Neighborhood Hits	12
SwissProt Accessions	P02798	Gene names	Mt2
Domain Architecture	No domain graphic available
Description	Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II).

ZNFX1_MOUSE
NC score	0.047446 (rank : 82)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	84	Target Neighborhood Hits	407	Shared Neighborhood Hits	27
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_HUMAN
NC score	0.045981 (rank : 83)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	84	Target Neighborhood Hits	308	Shared Neighborhood Hits	28
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

NPBL_MOUSE
NC score	0.045007 (rank : 84)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	84	Target Neighborhood Hits	1041	Shared Neighborhood Hits	18
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NCOR2_MOUSE
NC score	0.041615 (rank : 85)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	84	Target Neighborhood Hits	790	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

KR105_HUMAN
NC score	0.041224 (rank : 86)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	84	Target Neighborhood Hits	271	Shared Neighborhood Hits	28
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

NOTC2_HUMAN
NC score	0.040558 (rank : 87)	θ value	0.365318 (rank : 31)
Query Neighborhood Hits	84	Target Neighborhood Hits	1113	Shared Neighborhood Hits	44
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

RCOR2_MOUSE
NC score	0.037295 (rank : 88)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	84	Target Neighborhood Hits	107	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C796, Q9JMK4	Gene names	Rcor2
Domain Architecture	No domain graphic available
Description	REST corepressor 2 (M-CoREST).

ZAN_MOUSE
NC score	0.036993 (rank : 89)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	84	Target Neighborhood Hits	808	Shared Neighborhood Hits	38
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

ITB1_HUMAN
NC score	0.036893 (rank : 90)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	84	Target Neighborhood Hits	298	Shared Neighborhood Hits	28
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

NOTC2_MOUSE
NC score	0.036583 (rank : 91)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	84	Target Neighborhood Hits	1069	Shared Neighborhood Hits	39
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CENB5_HUMAN
NC score	0.035757 (rank : 92)	θ value	0.47712 (rank : 32)
Query Neighborhood Hits	84	Target Neighborhood Hits	395	Shared Neighborhood Hits	13
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

RCOR2_HUMAN
NC score	0.032372 (rank : 93)	θ value	5.27518 (rank : 63)
Query Neighborhood Hits	84	Target Neighborhood Hits	114	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZ40, Q96FP3	Gene names	RCOR2
Domain Architecture	No domain graphic available
Description	REST corepressor 2.

NOTC1_HUMAN
NC score	0.031944 (rank : 94)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	84	Target Neighborhood Hits	906	Shared Neighborhood Hits	32
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SSPO_MOUSE
NC score	0.031244 (rank : 95)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	84	Target Neighborhood Hits	800	Shared Neighborhood Hits	40
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

KRA52_HUMAN
NC score	0.031094 (rank : 96)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	84	Target Neighborhood Hits	236	Shared Neighborhood Hits	20
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

MYSM1_HUMAN
NC score	0.030674 (rank : 97)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	84	Target Neighborhood Hits	73	Shared Neighborhood Hits	10
SwissProt Accessions	Q5VVJ2, Q7Z3G8, Q96PX3	Gene names	MYSM1, KIAA1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

CRIM1_HUMAN
NC score	0.030425 (rank : 98)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	84	Target Neighborhood Hits	362	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

RCOR3_HUMAN
NC score	0.030285 (rank : 99)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	84	Target Neighborhood Hits	161	Shared Neighborhood Hits	9
SwissProt Accessions	Q9P2K3, Q5VT47, Q7L9I5, Q8N5U3, Q9NV83	Gene names	RCOR3, KIAA1343
Domain Architecture	No domain graphic available
Description	REST corepressor 3.

ITB1_MOUSE
NC score	0.029234 (rank : 100)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	84	Target Neighborhood Hits	283	Shared Neighborhood Hits	25
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

CJ012_HUMAN
NC score	0.029102 (rank : 101)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	84	Target Neighborhood Hits	467	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

VWF_MOUSE
NC score	0.028645 (rank : 102)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	84	Target Neighborhood Hits	381	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CIZ8, Q60863, Q6XUV6, Q8BIU9, Q8CGN0, Q9JK16	Gene names	Vwf
Domain Architecture	No domain graphic available
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

MIB1_HUMAN
NC score	0.028404 (rank : 103)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	84	Target Neighborhood Hits	470	Shared Neighborhood Hits	12
SwissProt Accessions	Q86YT6, Q68D01, Q6YI51, Q8NBY0, Q8TCB5, Q8TCL7, Q9P2M3	Gene names	MIB1, DIP1, KIAA1323, ZZANK2
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein MIB1 (EC 6.3.2.-) (Mind bomb homolog 1) (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ type with ankyrin repeat domain protein 2).

VEGFC_MOUSE
NC score	0.027175 (rank : 104)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	84	Target Neighborhood Hits	119	Shared Neighborhood Hits	14
SwissProt Accessions	P97953, Q543R6	Gene names	Vegfc
Domain Architecture
Description	Vascular endothelial growth factor C precursor (VEGF-C) (Vascular endothelial growth factor-related protein) (VRP) (Flt4 ligand) (Flt4- L).

IF4G3_MOUSE
NC score	0.025900 (rank : 105)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	84	Target Neighborhood Hits	279	Shared Neighborhood Hits	7
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

STAB1_HUMAN
NC score	0.020825 (rank : 106)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	84	Target Neighborhood Hits	546	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

MEGF6_HUMAN
NC score	0.019911 (rank : 107)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	84	Target Neighborhood Hits	671	Shared Neighborhood Hits	32
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

TGON1_MOUSE
NC score	0.019717 (rank : 108)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	84	Target Neighborhood Hits	243	Shared Neighborhood Hits	8
SwissProt Accessions	Q62313	Gene names	Tgoln1, Ttgn1
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 1 precursor (TGN38A).

KIF4A_HUMAN
NC score	0.017989 (rank : 109)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	84	Target Neighborhood Hits	1159	Shared Neighborhood Hits	20
SwissProt Accessions	O95239, Q86TN3, Q86XX7, Q9NNY6, Q9NY24, Q9UMW3	Gene names	KIF4A, KIF4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

OXRP_HUMAN
NC score	0.017869 (rank : 110)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	84	Target Neighborhood Hits	544	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PKHA6_HUMAN
NC score	0.017578 (rank : 111)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	84	Target Neighborhood Hits	556	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

DYNA_HUMAN
NC score	0.015647 (rank : 112)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	84	Target Neighborhood Hits	1194	Shared Neighborhood Hits	14
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

DLL1_HUMAN
NC score	0.015560 (rank : 113)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	84	Target Neighborhood Hits	455	Shared Neighborhood Hits	29
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DYNA_MOUSE
NC score	0.013834 (rank : 114)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	84	Target Neighborhood Hits	1084	Shared Neighborhood Hits	9
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

ATS13_MOUSE
NC score	0.013518 (rank : 115)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	84	Target Neighborhood Hits	227	Shared Neighborhood Hits	11
SwissProt Accessions	Q769J6, Q76LW1	Gene names	Adamts13
Domain Architecture	No domain graphic available
Description	ADAMTS-13 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 13) (ADAM-TS 13) (ADAM-TS13) (von Willebrand factor-cleaving protease) (vWF-cleaving protease) (vWF-CP).

ATL2_MOUSE
NC score	0.011752 (rank : 116)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	84	Target Neighborhood Hits	137	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TSK7, Q3U0C8	Gene names	Adamtsl2, Kiaa0605, Tcp1
Domain Architecture	No domain graphic available
Description	ADAMTS-like protein 2 precursor (ADAMTSL-2) (TSP1-repeats-containing protein 1) (TCP-1).

UB7I4_MOUSE
NC score	0.011299 (rank : 117)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	84	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	Q925F3, Q6A0B4	Gene names	Rnf144, Kiaa0161, Ubce7ip4, Uip4
Domain Architecture
Description	Ubiquitin-conjugating enzyme 7-interacting protein 4 (UbcM4- interacting protein 4) (RING finger protein 144).

KIF4A_MOUSE
NC score	0.010392 (rank : 118)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	84	Target Neighborhood Hits	1033	Shared Neighborhood Hits	19
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

UBP25_MOUSE
NC score	0.007612 (rank : 119)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	84	Target Neighborhood Hits	116	Shared Neighborhood Hits	4
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

PGBM_MOUSE
NC score	0.007592 (rank : 120)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	84	Target Neighborhood Hits	1073	Shared Neighborhood Hits	26
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

ALBU_MOUSE
NC score	0.007006 (rank : 121)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	84	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	P07724, Q61802	Gene names	Alb, Alb-1, Alb1
Domain Architecture
Description	Serum albumin precursor.

GP116_HUMAN
NC score	0.006947 (rank : 122)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	84	Target Neighborhood Hits	167	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZF2, O94858, Q6RGN2, Q86SP0, Q9Y3Z2	Gene names	GPR116, KIAA0758
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 116 precursor.

GPC6A_MOUSE
NC score	0.006242 (rank : 123)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	84	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K4Z6, Q5DK51, Q5DK52	Gene names	Gprc6a
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor.

BAI3_HUMAN
NC score	0.005793 (rank : 124)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	84	Target Neighborhood Hits	246	Shared Neighborhood Hits	9
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

FGD4_HUMAN
NC score	0.005645 (rank : 125)	θ value	5.27518 (rank : 61)
Query Neighborhood Hits	84	Target Neighborhood Hits	219	Shared Neighborhood Hits	4
SwissProt Accessions	Q96M96, Q6ULS2, Q8TCP6	Gene names	FGD4, FRABP, ZFYVE6
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 4 (Actin filament- binding protein frabin) (FGD1-related F-actin-binding protein) (Zinc finger FYVE domain-containing protein 6).

TIE2_MOUSE
NC score	0.000123 (rank : 126)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	84	Target Neighborhood Hits	1204	Shared Neighborhood Hits	19
SwissProt Accessions	Q02858	Gene names	Tek, Hyk, Tie-2, Tie2
Domain Architecture
Description	Angiopoietin-1 receptor precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor TIE-2) (mTIE2) (Tyrosine-protein kinase receptor TEK) (p140 TEK) (Tunica interna endothelial cell kinase) (HYK) (STK1) (CD202b antigen).

EGFR_HUMAN
NC score	-0.001354 (rank : 127)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	84	Target Neighborhood Hits	939	Shared Neighborhood Hits	13
SwissProt Accessions	P00533, O00688, O00732, P06268, Q14225, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5	Gene names	EGFR, ERBB1
Domain Architecture
Description	Epidermal growth factor receptor precursor (EC 2.7.10.1) (Receptor tyrosine-protein kinase ErbB-1).