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Network neighborhood for query Sequence : UBP10_MOUSE

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UBP10_MOUSE
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

UBP10_HUMAN
θ value	0 (rank : 1)	NC score	0.975313 (rank : 2)
Query Neighborhood Hits	150	Target Neighborhood Hits	153	Shared Neighborhood Hits	85
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP10_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	150	Target Neighborhood Hits	150	Shared Neighborhood Hits	150
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP8_HUMAN
θ value	9.24701e-21 (rank : 3)	NC score	0.709194 (rank : 20)
Query Neighborhood Hits	150	Target Neighborhood Hits	751	Shared Neighborhood Hits	82
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP8_MOUSE
θ value	3.51386e-20 (rank : 4)	NC score	0.741246 (rank : 6)
Query Neighborhood Hits	150	Target Neighborhood Hits	362	Shared Neighborhood Hits	74
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UB17L_HUMAN
θ value	8.95645e-16 (rank : 5)	NC score	0.750550 (rank : 5)
Query Neighborhood Hits	150	Target Neighborhood Hits	83	Shared Neighborhood Hits	69
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP42_HUMAN
θ value	1.16975e-15 (rank : 6)	NC score	0.716165 (rank : 18)
Query Neighborhood Hits	150	Target Neighborhood Hits	445	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP50_MOUSE
θ value	3.40345e-15 (rank : 7)	NC score	0.753422 (rank : 3)
Query Neighborhood Hits	150	Target Neighborhood Hits	80	Shared Neighborhood Hits	69
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBP46_HUMAN
θ value	4.44505e-15 (rank : 8)	NC score	0.739653 (rank : 7)
Query Neighborhood Hits	150	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
θ value	4.44505e-15 (rank : 9)	NC score	0.739653 (rank : 8)
Query Neighborhood Hits	150	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBPW_MOUSE
θ value	4.91457e-14 (rank : 10)	NC score	0.752280 (rank : 4)
Query Neighborhood Hits	150	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UBP36_HUMAN
θ value	2.43908e-13 (rank : 11)	NC score	0.722768 (rank : 15)
Query Neighborhood Hits	150	Target Neighborhood Hits	232	Shared Neighborhood Hits	75
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP3_MOUSE
θ value	3.18553e-13 (rank : 12)	NC score	0.736033 (rank : 10)
Query Neighborhood Hits	150	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP15_HUMAN
θ value	5.43371e-13 (rank : 13)	NC score	0.668979 (rank : 29)
Query Neighborhood Hits	150	Target Neighborhood Hits	92	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP15_MOUSE
θ value	5.43371e-13 (rank : 14)	NC score	0.669330 (rank : 27)
Query Neighborhood Hits	150	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP12_HUMAN
θ value	1.2105e-12 (rank : 15)	NC score	0.736049 (rank : 9)
Query Neighborhood Hits	150	Target Neighborhood Hits	85	Shared Neighborhood Hits	69
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP21_HUMAN
θ value	1.58096e-12 (rank : 16)	NC score	0.729330 (rank : 12)
Query Neighborhood Hits	150	Target Neighborhood Hits	95	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP21_MOUSE
θ value	7.84624e-12 (rank : 17)	NC score	0.726307 (rank : 14)
Query Neighborhood Hits	150	Target Neighborhood Hits	101	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP11_HUMAN
θ value	1.02475e-11 (rank : 18)	NC score	0.671024 (rank : 26)
Query Neighborhood Hits	150	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP2_HUMAN
θ value	5.08577e-11 (rank : 19)	NC score	0.721643 (rank : 16)
Query Neighborhood Hits	150	Target Neighborhood Hits	84	Shared Neighborhood Hits	70
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP3_HUMAN
θ value	1.47974e-10 (rank : 20)	NC score	0.729326 (rank : 13)
Query Neighborhood Hits	150	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP44_HUMAN
θ value	1.47974e-10 (rank : 21)	NC score	0.690967 (rank : 23)
Query Neighborhood Hits	150	Target Neighborhood Hits	91	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP50_HUMAN
θ value	1.9326e-10 (rank : 22)	NC score	0.730346 (rank : 11)
Query Neighborhood Hits	150	Target Neighborhood Hits	75	Shared Neighborhood Hits	64
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP22_MOUSE
θ value	9.59137e-10 (rank : 23)	NC score	0.711265 (rank : 19)
Query Neighborhood Hits	150	Target Neighborhood Hits	87	Shared Neighborhood Hits	69
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP2_MOUSE
θ value	9.59137e-10 (rank : 24)	NC score	0.716386 (rank : 17)
Query Neighborhood Hits	150	Target Neighborhood Hits	86	Shared Neighborhood Hits	69
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP48_HUMAN
θ value	1.63604e-09 (rank : 25)	NC score	0.647255 (rank : 32)
Query Neighborhood Hits	150	Target Neighborhood Hits	101	Shared Neighborhood Hits	69
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP48_MOUSE
θ value	1.63604e-09 (rank : 26)	NC score	0.645152 (rank : 33)
Query Neighborhood Hits	150	Target Neighborhood Hits	124	Shared Neighborhood Hits	69
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP22_HUMAN
θ value	2.79066e-09 (rank : 27)	NC score	0.708998 (rank : 21)
Query Neighborhood Hits	150	Target Neighborhood Hits	87	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP49_MOUSE
θ value	2.79066e-09 (rank : 28)	NC score	0.674604 (rank : 25)
Query Neighborhood Hits	150	Target Neighborhood Hits	91	Shared Neighborhood Hits	69
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP49_HUMAN
θ value	3.64472e-09 (rank : 29)	NC score	0.675131 (rank : 24)
Query Neighborhood Hits	150	Target Neighborhood Hits	100	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP14_HUMAN
θ value	1.38499e-08 (rank : 30)	NC score	0.596021 (rank : 41)
Query Neighborhood Hits	150	Target Neighborhood Hits	89	Shared Neighborhood Hits	67
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP14_MOUSE
θ value	1.38499e-08 (rank : 31)	NC score	0.592282 (rank : 42)
Query Neighborhood Hits	150	Target Neighborhood Hits	87	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

USP9X_MOUSE
θ value	1.80886e-08 (rank : 32)	NC score	0.538301 (rank : 51)
Query Neighborhood Hits	150	Target Neighborhood Hits	171	Shared Neighborhood Hits	70
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

UBP4_HUMAN
θ value	5.26297e-08 (rank : 33)	NC score	0.645034 (rank : 34)
Query Neighborhood Hits	150	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP4_MOUSE
θ value	5.26297e-08 (rank : 34)	NC score	0.643611 (rank : 35)
Query Neighborhood Hits	150	Target Neighborhood Hits	90	Shared Neighborhood Hits	69
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP33_HUMAN
θ value	6.87365e-08 (rank : 35)	NC score	0.669310 (rank : 28)
Query Neighborhood Hits	150	Target Neighborhood Hits	157	Shared Neighborhood Hits	71
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

USP9X_HUMAN
θ value	8.97725e-08 (rank : 36)	NC score	0.535439 (rank : 53)
Query Neighborhood Hits	150	Target Neighborhood Hits	161	Shared Neighborhood Hits	70
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

UBP51_HUMAN
θ value	3.41135e-07 (rank : 37)	NC score	0.699301 (rank : 22)
Query Neighborhood Hits	150	Target Neighborhood Hits	162	Shared Neighborhood Hits	72
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

USP9Y_HUMAN
θ value	1.69304e-06 (rank : 38)	NC score	0.530778 (rank : 54)
Query Neighborhood Hits	150	Target Neighborhood Hits	109	Shared Neighborhood Hits	69
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

UBP20_HUMAN
θ value	6.43352e-06 (rank : 39)	NC score	0.661555 (rank : 31)
Query Neighborhood Hits	150	Target Neighborhood Hits	113	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP37_HUMAN
θ value	1.09739e-05 (rank : 40)	NC score	0.550982 (rank : 47)
Query Neighborhood Hits	150	Target Neighborhood Hits	208	Shared Neighborhood Hits	69
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

UBP43_MOUSE
θ value	1.09739e-05 (rank : 41)	NC score	0.618843 (rank : 36)
Query Neighborhood Hits	150	Target Neighborhood Hits	130	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP16_HUMAN
θ value	1.43324e-05 (rank : 42)	NC score	0.663391 (rank : 30)
Query Neighborhood Hits	150	Target Neighborhood Hits	126	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP43_HUMAN
θ value	1.43324e-05 (rank : 43)	NC score	0.615127 (rank : 38)
Query Neighborhood Hits	150	Target Neighborhood Hits	144	Shared Neighborhood Hits	71
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP7_HUMAN
θ value	1.43324e-05 (rank : 44)	NC score	0.587265 (rank : 43)
Query Neighborhood Hits	150	Target Neighborhood Hits	93	Shared Neighborhood Hits	66
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP18_HUMAN
θ value	3.19293e-05 (rank : 45)	NC score	0.615357 (rank : 37)
Query Neighborhood Hits	150	Target Neighborhood Hits	81	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP1_HUMAN
θ value	3.19293e-05 (rank : 46)	NC score	0.611951 (rank : 39)
Query Neighborhood Hits	150	Target Neighborhood Hits	259	Shared Neighborhood Hits	74
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

SNUT2_MOUSE
θ value	4.1701e-05 (rank : 47)	NC score	0.565106 (rank : 46)
Query Neighborhood Hits	150	Target Neighborhood Hits	80	Shared Neighborhood Hits	57
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

SNUT2_HUMAN
θ value	0.000158464 (rank : 48)	NC score	0.548050 (rank : 48)
Query Neighborhood Hits	150	Target Neighborhood Hits	79	Shared Neighborhood Hits	55
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

UBP31_HUMAN
θ value	0.00020696 (rank : 49)	NC score	0.607191 (rank : 40)
Query Neighborhood Hits	150	Target Neighborhood Hits	293	Shared Neighborhood Hits	82
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP24_HUMAN
θ value	0.000602161 (rank : 50)	NC score	0.567658 (rank : 44)
Query Neighborhood Hits	150	Target Neighborhood Hits	96	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP26_MOUSE
θ value	0.000786445 (rank : 51)	NC score	0.436234 (rank : 66)
Query Neighborhood Hits	150	Target Neighborhood Hits	107	Shared Neighborhood Hits	69
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP26_HUMAN
θ value	0.00102713 (rank : 52)	NC score	0.484729 (rank : 61)
Query Neighborhood Hits	150	Target Neighborhood Hits	108	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP47_MOUSE
θ value	0.00102713 (rank : 53)	NC score	0.542144 (rank : 50)
Query Neighborhood Hits	150	Target Neighborhood Hits	135	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP29_HUMAN
θ value	0.00390308 (rank : 54)	NC score	0.493668 (rank : 59)
Query Neighborhood Hits	150	Target Neighborhood Hits	94	Shared Neighborhood Hits	67
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP47_HUMAN
θ value	0.00390308 (rank : 55)	NC score	0.538127 (rank : 52)
Query Neighborhood Hits	150	Target Neighborhood Hits	149	Shared Neighborhood Hits	68
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

UBP29_MOUSE
θ value	0.0113563 (rank : 56)	NC score	0.470823 (rank : 63)
Query Neighborhood Hits	150	Target Neighborhood Hits	95	Shared Neighborhood Hits	67
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

BASP_HUMAN
θ value	0.0148317 (rank : 57)	NC score	0.068600 (rank : 77)
Query Neighborhood Hits	150	Target Neighborhood Hits	321	Shared Neighborhood Hits	17
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

UBP35_HUMAN
θ value	0.0148317 (rank : 58)	NC score	0.524328 (rank : 55)
Query Neighborhood Hits	150	Target Neighborhood Hits	223	Shared Neighborhood Hits	70
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

RBM19_MOUSE
θ value	0.0193708 (rank : 59)	NC score	0.027602 (rank : 102)
Query Neighborhood Hits	150	Target Neighborhood Hits	296	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

UBP30_HUMAN
θ value	0.0193708 (rank : 60)	NC score	0.566845 (rank : 45)
Query Neighborhood Hits	150	Target Neighborhood Hits	94	Shared Neighborhood Hits	66
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

UBP5_HUMAN
θ value	0.0252991 (rank : 61)	NC score	0.423973 (rank : 67)
Query Neighborhood Hits	150	Target Neighborhood Hits	109	Shared Neighborhood Hits	70
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP38_HUMAN
θ value	0.0330416 (rank : 62)	NC score	0.492363 (rank : 60)
Query Neighborhood Hits	150	Target Neighborhood Hits	97	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP13_HUMAN
θ value	0.0563607 (rank : 63)	NC score	0.406520 (rank : 69)
Query Neighborhood Hits	150	Target Neighborhood Hits	99	Shared Neighborhood Hits	69
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP32_HUMAN
θ value	0.0563607 (rank : 64)	NC score	0.523349 (rank : 56)
Query Neighborhood Hits	150	Target Neighborhood Hits	170	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

NFH_MOUSE
θ value	0.0736092 (rank : 65)	NC score	0.035488 (rank : 94)
Query Neighborhood Hits	150	Target Neighborhood Hits	2247	Shared Neighborhood Hits	67
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

UBP25_HUMAN
θ value	0.0736092 (rank : 66)	NC score	0.297859 (rank : 70)
Query Neighborhood Hits	150	Target Neighborhood Hits	124	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP5_MOUSE
θ value	0.0736092 (rank : 67)	NC score	0.415108 (rank : 68)
Query Neighborhood Hits	150	Target Neighborhood Hits	106	Shared Neighborhood Hits	70
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP6_HUMAN
θ value	0.0736092 (rank : 68)	NC score	0.496556 (rank : 58)
Query Neighborhood Hits	150	Target Neighborhood Hits	188	Shared Neighborhood Hits	73
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

NACAM_MOUSE
θ value	0.125558 (rank : 69)	NC score	0.047925 (rank : 84)
Query Neighborhood Hits	150	Target Neighborhood Hits	1866	Shared Neighborhood Hits	56
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NFH_HUMAN
θ value	0.125558 (rank : 70)	NC score	0.022152 (rank : 113)
Query Neighborhood Hits	150	Target Neighborhood Hits	1242	Shared Neighborhood Hits	33
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

HSP74_MOUSE
θ value	0.163984 (rank : 71)	NC score	0.021122 (rank : 117)
Query Neighborhood Hits	150	Target Neighborhood Hits	257	Shared Neighborhood Hits	7
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

AP180_HUMAN
θ value	0.21417 (rank : 72)	NC score	0.055674 (rank : 81)
Query Neighborhood Hits	150	Target Neighborhood Hits	183	Shared Neighborhood Hits	12
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

RD23B_HUMAN
θ value	0.21417 (rank : 73)	NC score	0.045129 (rank : 86)
Query Neighborhood Hits	150	Target Neighborhood Hits	115	Shared Neighborhood Hits	13
SwissProt Accessions	P54727, Q8WUB0	Gene names	RAD23B
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (hHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

HCN1_HUMAN
θ value	0.279714 (rank : 74)	NC score	0.021725 (rank : 114)
Query Neighborhood Hits	150	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

OKL38_HUMAN
θ value	0.365318 (rank : 75)	NC score	0.040523 (rank : 88)
Query Neighborhood Hits	150	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJX0, Q86UQ1, Q96S88, Q9BZ70	Gene names	OKL38
Domain Architecture
Description	Pregnancy-induced growth inhibitor OKL38 (huOKL38) (Ovary, kidney and liver protein 38).

CJ030_MOUSE
θ value	0.47712 (rank : 76)	NC score	0.036353 (rank : 93)
Query Neighborhood Hits	150	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BSV3, Q4VAD9, Q6PHN3, Q8BPJ4, Q8C973	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf30 homolog.

HCN1_MOUSE
θ value	0.47712 (rank : 77)	NC score	0.020935 (rank : 118)
Query Neighborhood Hits	150	Target Neighborhood Hits	172	Shared Neighborhood Hits	8
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

LDB3_MOUSE
θ value	0.47712 (rank : 78)	NC score	0.015162 (rank : 127)
Query Neighborhood Hits	150	Target Neighborhood Hits	510	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

MAGE1_HUMAN
θ value	0.47712 (rank : 79)	NC score	0.036514 (rank : 92)
Query Neighborhood Hits	150	Target Neighborhood Hits	1389	Shared Neighborhood Hits	46
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

NFRKB_MOUSE
θ value	0.47712 (rank : 80)	NC score	0.042238 (rank : 87)
Query Neighborhood Hits	150	Target Neighborhood Hits	393	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

TBX6_HUMAN
θ value	0.47712 (rank : 81)	NC score	0.012917 (rank : 131)
Query Neighborhood Hits	150	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	O95947, Q8TAS4	Gene names	TBX6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

TIAM1_MOUSE
θ value	0.47712 (rank : 82)	NC score	0.018540 (rank : 120)
Query Neighborhood Hits	150	Target Neighborhood Hits	205	Shared Neighborhood Hits	6
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

UBP38_MOUSE
θ value	0.62314 (rank : 83)	NC score	0.477954 (rank : 62)
Query Neighborhood Hits	150	Target Neighborhood Hits	100	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

MUC7_HUMAN
θ value	0.813845 (rank : 84)	NC score	0.037748 (rank : 90)
Query Neighborhood Hits	150	Target Neighborhood Hits	538	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PO2F1_MOUSE
θ value	0.813845 (rank : 85)	NC score	0.013480 (rank : 130)
Query Neighborhood Hits	150	Target Neighborhood Hits	408	Shared Neighborhood Hits	13
SwissProt Accessions	P25425, Q61994, Q63891, Q6Y681, Q7TSD0, Q8BT04, Q8K570, Q99JH0, Q9WTZ4, Q9WTZ5, Q9WTZ6	Gene names	Pou2f1, Oct-1, Otf-1, Otf1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

TGON2_HUMAN
θ value	0.813845 (rank : 86)	NC score	0.046320 (rank : 85)
Query Neighborhood Hits	150	Target Neighborhood Hits	1037	Shared Neighborhood Hits	44
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

AP180_MOUSE
θ value	1.06291 (rank : 87)	NC score	0.048232 (rank : 83)
Query Neighborhood Hits	150	Target Neighborhood Hits	194	Shared Neighborhood Hits	12
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

FMN2_HUMAN
θ value	1.06291 (rank : 88)	NC score	0.021701 (rank : 115)
Query Neighborhood Hits	150	Target Neighborhood Hits	484	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

PKHA6_HUMAN
θ value	1.06291 (rank : 89)	NC score	0.031409 (rank : 97)
Query Neighborhood Hits	150	Target Neighborhood Hits	556	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

X3CL1_HUMAN
θ value	1.06291 (rank : 90)	NC score	0.029056 (rank : 99)
Query Neighborhood Hits	150	Target Neighborhood Hits	152	Shared Neighborhood Hits	9
SwissProt Accessions	P78423, O00672	Gene names	CX3CL1, A-152E5.2, FKN, NTT, SCYD1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

GPR98_HUMAN
θ value	1.38821 (rank : 91)	NC score	0.016156 (rank : 124)
Query Neighborhood Hits	150	Target Neighborhood Hits	202	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

LAP4_MOUSE
θ value	1.38821 (rank : 92)	NC score	0.007786 (rank : 143)
Query Neighborhood Hits	150	Target Neighborhood Hits	590	Shared Neighborhood Hits	11
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

RBBP6_MOUSE
θ value	1.38821 (rank : 93)	NC score	0.028678 (rank : 100)
Query Neighborhood Hits	150	Target Neighborhood Hits	1014	Shared Neighborhood Hits	24
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

UBP25_MOUSE
θ value	1.38821 (rank : 94)	NC score	0.288665 (rank : 73)
Query Neighborhood Hits	150	Target Neighborhood Hits	116	Shared Neighborhood Hits	68
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

DDX24_HUMAN
θ value	1.81305 (rank : 95)	NC score	0.009318 (rank : 139)
Query Neighborhood Hits	150	Target Neighborhood Hits	190	Shared Neighborhood Hits	10
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

K0460_MOUSE
θ value	1.81305 (rank : 96)	NC score	0.027624 (rank : 101)
Query Neighborhood Hits	150	Target Neighborhood Hits	374	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

MAP4_MOUSE
θ value	1.81305 (rank : 97)	NC score	0.034179 (rank : 95)
Query Neighborhood Hits	150	Target Neighborhood Hits	409	Shared Neighborhood Hits	26
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

RUFY2_HUMAN
θ value	1.81305 (rank : 98)	NC score	0.007755 (rank : 144)
Query Neighborhood Hits	150	Target Neighborhood Hits	1208	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

SLIK6_MOUSE
θ value	1.81305 (rank : 99)	NC score	0.004746 (rank : 152)
Query Neighborhood Hits	150	Target Neighborhood Hits	302	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C110, Q8BLL0	Gene names	Slitrk6, Sltk6
Domain Architecture
Description	SLIT and NTRK-like protein 6 precursor.

HSP74_HUMAN
θ value	2.36792 (rank : 100)	NC score	0.016758 (rank : 122)
Query Neighborhood Hits	150	Target Neighborhood Hits	154	Shared Neighborhood Hits	8
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

INT1_MOUSE
θ value	2.36792 (rank : 101)	NC score	0.021522 (rank : 116)
Query Neighborhood Hits	150	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P4S8, Q80UQ7, Q91Z01, Q9CTF7	Gene names	Ints1
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 1 (Int1).

PK3C3_MOUSE
θ value	2.36792 (rank : 102)	NC score	0.014134 (rank : 128)
Query Neighborhood Hits	150	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PF93, Q8R3S8	Gene names	Pik3c3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3).

THAP8_HUMAN
θ value	2.36792 (rank : 103)	NC score	0.026216 (rank : 106)
Query Neighborhood Hits	150	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NA92, Q96M21	Gene names	THAP8
Domain Architecture
Description	THAP domain-containing protein 8.

UBP28_HUMAN
θ value	2.36792 (rank : 104)	NC score	0.296849 (rank : 71)
Query Neighborhood Hits	150	Target Neighborhood Hits	117	Shared Neighborhood Hits	68
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

ABL1_MOUSE
θ value	3.0926 (rank : 105)	NC score	-0.002546 (rank : 158)
Query Neighborhood Hits	150	Target Neighborhood Hits	1178	Shared Neighborhood Hits	18
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

BASP_MOUSE
θ value	3.0926 (rank : 106)	NC score	0.050824 (rank : 82)
Query Neighborhood Hits	150	Target Neighborhood Hits	260	Shared Neighborhood Hits	18
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

BSN_HUMAN
θ value	3.0926 (rank : 107)	NC score	0.026588 (rank : 104)
Query Neighborhood Hits	150	Target Neighborhood Hits	1537	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BSN_MOUSE
θ value	3.0926 (rank : 108)	NC score	0.026473 (rank : 105)
Query Neighborhood Hits	150	Target Neighborhood Hits	2057	Shared Neighborhood Hits	55
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CD2L2_HUMAN
θ value	3.0926 (rank : 109)	NC score	-0.001840 (rank : 157)
Query Neighborhood Hits	150	Target Neighborhood Hits	1439	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CIZ1_HUMAN
θ value	3.0926 (rank : 110)	NC score	0.026030 (rank : 108)
Query Neighborhood Hits	150	Target Neighborhood Hits	359	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

GNAS1_MOUSE
θ value	3.0926 (rank : 111)	NC score	0.009601 (rank : 137)
Query Neighborhood Hits	150	Target Neighborhood Hits	651	Shared Neighborhood Hits	20
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

LATS1_MOUSE
θ value	3.0926 (rank : 112)	NC score	-0.000148 (rank : 156)
Query Neighborhood Hits	150	Target Neighborhood Hits	1027	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

RERE_HUMAN
θ value	3.0926 (rank : 113)	NC score	0.024727 (rank : 109)
Query Neighborhood Hits	150	Target Neighborhood Hits	779	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

RERE_MOUSE
θ value	3.0926 (rank : 114)	NC score	0.026176 (rank : 107)
Query Neighborhood Hits	150	Target Neighborhood Hits	785	Shared Neighborhood Hits	28
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

UBP28_MOUSE
θ value	3.0926 (rank : 115)	NC score	0.292529 (rank : 72)
Query Neighborhood Hits	150	Target Neighborhood Hits	178	Shared Neighborhood Hits	70
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

ZN335_HUMAN
θ value	3.0926 (rank : 116)	NC score	-0.002669 (rank : 159)
Query Neighborhood Hits	150	Target Neighborhood Hits	973	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

ZN592_MOUSE
θ value	3.0926 (rank : 117)	NC score	0.002677 (rank : 154)
Query Neighborhood Hits	150	Target Neighborhood Hits	768	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).

ANC5_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.016079 (rank : 125)
Query Neighborhood Hits	150	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJX4, Q8N4H7, Q9BQD4	Gene names	ANAPC5, APC5
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5).

LAP4_HUMAN
θ value	4.03905 (rank : 119)	NC score	0.007232 (rank : 146)
Query Neighborhood Hits	150	Target Neighborhood Hits	608	Shared Neighborhood Hits	14
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

MAP1B_HUMAN
θ value	4.03905 (rank : 120)	NC score	0.022531 (rank : 112)
Query Neighborhood Hits	150	Target Neighborhood Hits	903	Shared Neighborhood Hits	25
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

NCA11_MOUSE
θ value	4.03905 (rank : 121)	NC score	0.008723 (rank : 141)
Query Neighborhood Hits	150	Target Neighborhood Hits	661	Shared Neighborhood Hits	20
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

NFRKB_HUMAN
θ value	4.03905 (rank : 122)	NC score	0.036774 (rank : 91)
Query Neighborhood Hits	150	Target Neighborhood Hits	211	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

PKHA6_MOUSE
θ value	4.03905 (rank : 123)	NC score	0.026924 (rank : 103)
Query Neighborhood Hits	150	Target Neighborhood Hits	591	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

SAPS2_HUMAN
θ value	4.03905 (rank : 124)	NC score	0.011259 (rank : 134)
Query Neighborhood Hits	150	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	O75170, Q9UGB9	Gene names	SAPS2, KIAA0685
Domain Architecture
Description	SAPS domain family member 2.

SREC_HUMAN
θ value	4.03905 (rank : 125)	NC score	0.003138 (rank : 153)
Query Neighborhood Hits	150	Target Neighborhood Hits	645	Shared Neighborhood Hits	7
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

SRRM2_HUMAN
θ value	4.03905 (rank : 126)	NC score	0.022684 (rank : 111)
Query Neighborhood Hits	150	Target Neighborhood Hits	1296	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

EVL_MOUSE
θ value	5.27518 (rank : 127)	NC score	0.023208 (rank : 110)
Query Neighborhood Hits	150	Target Neighborhood Hits	203	Shared Neighborhood Hits	18
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

FGD5_MOUSE
θ value	5.27518 (rank : 128)	NC score	0.009173 (rank : 140)
Query Neighborhood Hits	150	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

RUFY2_MOUSE
θ value	5.27518 (rank : 129)	NC score	0.007208 (rank : 147)
Query Neighborhood Hits	150	Target Neighborhood Hits	820	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

CUL4B_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.006017 (rank : 149)
Query Neighborhood Hits	150	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q13620, Q6PIE4, Q6UP07, Q7Z673, Q9BY37, Q9UEB7, Q9UED7	Gene names	CUL4B, KIAA0695
Domain Architecture
Description	Cullin-4B (CUL-4B).

DDX51_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.007891 (rank : 142)
Query Neighborhood Hits	150	Target Neighborhood Hits	332	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

IL4RA_MOUSE
θ value	6.88961 (rank : 132)	NC score	0.012786 (rank : 132)
Query Neighborhood Hits	150	Target Neighborhood Hits	194	Shared Neighborhood Hits	12
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

KCC2B_HUMAN
θ value	6.88961 (rank : 133)	NC score	-0.004346 (rank : 160)
Query Neighborhood Hits	150	Target Neighborhood Hits	866	Shared Neighborhood Hits	8
SwissProt Accessions	Q13554, O95437, O95438, O95599, Q9UGH7, Q9UGH8, Q9UGH9, Q9UNX0, Q9UNX7, Q9UP00, Q9Y5N4, Q9Y6F4	Gene names	CAMK2B, CAM2, CAMKB
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).

MINT_MOUSE
θ value	6.88961 (rank : 134)	NC score	0.030200 (rank : 98)
Query Neighborhood Hits	150	Target Neighborhood Hits	1514	Shared Neighborhood Hits	47
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SYNJ1_MOUSE
θ value	6.88961 (rank : 135)	NC score	0.013986 (rank : 129)
Query Neighborhood Hits	150	Target Neighborhood Hits	516	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ZN592_HUMAN
θ value	6.88961 (rank : 136)	NC score	0.001549 (rank : 155)
Query Neighborhood Hits	150	Target Neighborhood Hits	762	Shared Neighborhood Hits	11
SwissProt Accessions	Q92610	Gene names	ZNF592, KIAA0211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592.

AMOT_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.009524 (rank : 138)
Query Neighborhood Hits	150	Target Neighborhood Hits	712	Shared Neighborhood Hits	17
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

ASXL1_MOUSE
θ value	8.99809 (rank : 138)	NC score	0.018339 (rank : 121)
Query Neighborhood Hits	150	Target Neighborhood Hits	182	Shared Neighborhood Hits	15
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

BICD2_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.005206 (rank : 151)
Query Neighborhood Hits	150	Target Neighborhood Hits	856	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.005661 (rank : 150)
Query Neighborhood Hits	150	Target Neighborhood Hits	864	Shared Neighborhood Hits	18
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

CENPB_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.007742 (rank : 145)
Query Neighborhood Hits	150	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	P07199	Gene names	CENPB
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

ELK4_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.006305 (rank : 148)
Query Neighborhood Hits	150	Target Neighborhood Hits	184	Shared Neighborhood Hits	11
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

MAP1B_MOUSE
θ value	8.99809 (rank : 143)	NC score	0.020021 (rank : 119)
Query Neighborhood Hits	150	Target Neighborhood Hits	977	Shared Neighborhood Hits	29
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

NU214_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.039742 (rank : 89)
Query Neighborhood Hits	150	Target Neighborhood Hits	657	Shared Neighborhood Hits	24
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

OXA1L_HUMAN
θ value	8.99809 (rank : 145)	NC score	0.015437 (rank : 126)
Query Neighborhood Hits	150	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q15070	Gene names	OXA1L
Domain Architecture
Description	Inner membrane protein OXA1L, mitochondrial precursor (Oxidase assembly 1-like protein) (OXA1-like protein) (OXA1Hs) (Hsa).

PK3C3_HUMAN
θ value	8.99809 (rank : 146)	NC score	0.010843 (rank : 135)
Query Neighborhood Hits	150	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NEB9, Q15134	Gene names	PIK3C3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3) (Phosphatidylinositol 3-kinase p100 subunit).

RANB3_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.016573 (rank : 123)
Query Neighborhood Hits	150	Target Neighborhood Hits	117	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H6Z4, O60405, O75759, O75760, Q9BT47, Q9UG74	Gene names	RANBP3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

SRRM2_MOUSE
θ value	8.99809 (rank : 148)	NC score	0.033277 (rank : 96)
Query Neighborhood Hits	150	Target Neighborhood Hits	1470	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TBCD4_MOUSE
θ value	8.99809 (rank : 149)	NC score	0.011908 (rank : 133)
Query Neighborhood Hits	150	Target Neighborhood Hits	276	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TENS1_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.010044 (rank : 136)
Query Neighborhood Hits	150	Target Neighborhood Hits	400	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

BRAP_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.074548 (rank : 76)
Query Neighborhood Hits	150	Target Neighborhood Hits	560	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.086237 (rank : 74)
Query Neighborhood Hits	150	Target Neighborhood Hits	409	Shared Neighborhood Hits	19
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

GGNB1_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.062788 (rank : 78)
Query Neighborhood Hits	150	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q5YKI7, Q5YKI8	Gene names	GGNBP1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

GGNB1_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.078273 (rank : 75)
Query Neighborhood Hits	150	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q6K1E7, Q8C5T9	Gene names	Ggnbp1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

HDAC6_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.058105 (rank : 80)
Query Neighborhood Hits	150	Target Neighborhood Hits	145	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

HDAC6_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.060666 (rank : 79)
Query Neighborhood Hits	150	Target Neighborhood Hits	88	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

UBP18_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.543926 (rank : 49)
Query Neighborhood Hits	150	Target Neighborhood Hits	77	Shared Neighborhood Hits	65
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP34_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.441461 (rank : 64)
Query Neighborhood Hits	150	Target Neighborhood Hits	210	Shared Neighborhood Hits	71
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.441285 (rank : 65)
Query Neighborhood Hits	150	Target Neighborhood Hits	189	Shared Neighborhood Hits	71
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP40_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.511225 (rank : 57)
Query Neighborhood Hits	150	Target Neighborhood Hits	81	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

Hits sorted by NC score

UBP10_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	150	Target Neighborhood Hits	150	Shared Neighborhood Hits	150
SwissProt Accessions	P52479, Q91VY7	Gene names	Usp10, Ode-1, Uchrp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP10_HUMAN
NC score	0.975313 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	150	Target Neighborhood Hits	153	Shared Neighborhood Hits	85
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

UBP50_MOUSE
NC score	0.753422 (rank : 3)	θ value	3.40345e-15 (rank : 7)
Query Neighborhood Hits	150	Target Neighborhood Hits	80	Shared Neighborhood Hits	69
SwissProt Accessions	Q6P8X6, Q9D558, Q9D9E7	Gene names	Usp50
Domain Architecture	No domain graphic available
Description	Putative ubiquitin carboxyl-terminal hydrolase 50 (EC 3.1.2.15) (Ubiquitin thioesterase 50) (Ubiquitin-specific-processing protease 50) (Deubiquitinating enzyme 50).

UBPW_MOUSE
NC score	0.752280 (rank : 4)	θ value	4.91457e-14 (rank : 10)
Query Neighborhood Hits	150	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	Q61068	Gene names	Dub1, Dub-1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase DUB-1 (EC 3.1.2.15) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1) (Deubiquitinating enzyme 1).

UB17L_HUMAN
NC score	0.750550 (rank : 5)	θ value	8.95645e-16 (rank : 5)
Query Neighborhood Hits	150	Target Neighborhood Hits	83	Shared Neighborhood Hits	69
SwissProt Accessions	Q7RTZ2	Gene names	USP17L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 17-like protein (EC 3.1.2.15) (Ubiquitin thioesterase 17-like) (Ubiquitin-specific-processing protease 17-like) (Deubiquitinating enzyme 17-like).

UBP8_MOUSE
NC score	0.741246 (rank : 6)	θ value	3.51386e-20 (rank : 4)
Query Neighborhood Hits	150	Target Neighborhood Hits	362	Shared Neighborhood Hits	74
SwissProt Accessions	Q80U87, Q80YP2, Q8R0D3, Q9EQU1, Q9WVP5	Gene names	Usp8, Kiaa0055, Ubpy
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (mUBPy).

UBP46_HUMAN
NC score	0.739653 (rank : 7)	θ value	4.44505e-15 (rank : 8)
Query Neighborhood Hits	150	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	P62068, Q80V95, Q9H7U4, Q9H9T8	Gene names	USP46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP46_MOUSE
NC score	0.739653 (rank : 8)	θ value	4.44505e-15 (rank : 9)
Query Neighborhood Hits	150	Target Neighborhood Hits	81	Shared Neighborhood Hits	69
SwissProt Accessions	P62069, Q80V95, Q9H7U4, Q9H9T8	Gene names	Usp46
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.1.2.15) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) (Deubiquitinating enzyme 46).

UBP12_HUMAN
NC score	0.736049 (rank : 9)	θ value	1.2105e-12 (rank : 15)
Query Neighborhood Hits	150	Target Neighborhood Hits	85	Shared Neighborhood Hits	69
SwissProt Accessions	O75317	Gene names	USP12, UBH1, USP12L1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.1.2.15) (Ubiquitin thioesterase 12) (Ubiquitin-specific-processing protease 12) (Deubiquitinating enzyme 12) (Ubiquitin-hydrolyzing enzyme 1).

UBP3_MOUSE
NC score	0.736033 (rank : 10)	θ value	3.18553e-13 (rank : 12)
Query Neighborhood Hits	150	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	Q91W36	Gene names	Usp3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP50_HUMAN
NC score	0.730346 (rank : 11)	θ value	1.9326e-10 (rank : 22)
Query Neighborhood Hits	150	Target Neighborhood Hits	75	Shared Neighborhood Hits	64
SwissProt Accessions	Q70EL3	Gene names	USP50
Domain Architecture	No domain graphic available
Description	Inactive ubiquitin carboxyl-terminal hydrolase 50 (Inactive ubiquitin- specific peptidase 50).

UBP21_HUMAN
NC score	0.729330 (rank : 12)	θ value	1.58096e-12 (rank : 16)
Query Neighborhood Hits	150	Target Neighborhood Hits	95	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UK80, Q9BTV1, Q9NYN4	Gene names	USP21, USP23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21) (NEDD8-specific protease).

UBP3_HUMAN
NC score	0.729326 (rank : 13)	θ value	1.47974e-10 (rank : 20)
Query Neighborhood Hits	150	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y6I4	Gene names	USP3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 3 (EC 3.1.2.15) (Ubiquitin thioesterase 3) (Ubiquitin-specific-processing protease 3) (Deubiquitinating enzyme 3).

UBP21_MOUSE
NC score	0.726307 (rank : 14)	θ value	7.84624e-12 (rank : 17)
Query Neighborhood Hits	150	Target Neighborhood Hits	101	Shared Neighborhood Hits	69
SwissProt Accessions	Q9QZL6, Q9D0R1	Gene names	Usp21, Usp23
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.1.2.15) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21) (Deubiquitinating enzyme 21).

UBP36_HUMAN
NC score	0.722768 (rank : 15)	θ value	2.43908e-13 (rank : 11)
Query Neighborhood Hits	150	Target Neighborhood Hits	232	Shared Neighborhood Hits	75
SwissProt Accessions	Q9P275, Q8NDM8, Q9NVC8	Gene names	USP36, KIAA1453
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 36 (EC 3.1.2.15) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36) (Deubiquitinating enzyme 36).

UBP2_HUMAN
NC score	0.721643 (rank : 16)	θ value	5.08577e-11 (rank : 19)
Query Neighborhood Hits	150	Target Neighborhood Hits	84	Shared Neighborhood Hits	70
SwissProt Accessions	O75604, Q96MB9, Q9BQ21	Gene names	USP2, UBP41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP2_MOUSE
NC score	0.716386 (rank : 17)	θ value	9.59137e-10 (rank : 24)
Query Neighborhood Hits	150	Target Neighborhood Hits	86	Shared Neighborhood Hits	69
SwissProt Accessions	O88623, Q6X4T9, Q6X4U1, Q8VD74, Q9JJ87	Gene names	Usp2, Ubp41
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.1.2.15) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2) (Deubiquitinating enzyme 2) (41 kDa ubiquitin-specific protease).

UBP42_HUMAN
NC score	0.716165 (rank : 18)	θ value	1.16975e-15 (rank : 6)
Query Neighborhood Hits	150	Target Neighborhood Hits	445	Shared Neighborhood Hits	85
SwissProt Accessions	Q9H9J4, Q3C166, Q6P9B4	Gene names	USP42
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 42 (EC 3.1.2.15) (Ubiquitin thioesterase 42) (Ubiquitin-specific-processing protease 42) (Deubiquitinating enzyme 42).

UBP22_MOUSE
NC score	0.711265 (rank : 19)	θ value	9.59137e-10 (rank : 23)
Query Neighborhood Hits	150	Target Neighborhood Hits	87	Shared Neighborhood Hits	69
SwissProt Accessions	Q5DU02, Q5SU81, Q66JV8	Gene names	Usp22, Kiaa1063
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP8_HUMAN
NC score	0.709194 (rank : 20)	θ value	9.24701e-21 (rank : 3)
Query Neighborhood Hits	150	Target Neighborhood Hits	751	Shared Neighborhood Hits	82
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

UBP22_HUMAN
NC score	0.708998 (rank : 21)	θ value	2.79066e-09 (rank : 27)
Query Neighborhood Hits	150	Target Neighborhood Hits	87	Shared Neighborhood Hits	69
SwissProt Accessions	Q9UPT9	Gene names	USP22, KIAA1063, USP3L
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.1.2.15) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22) (Deubiquitinating enzyme 22).

UBP51_HUMAN
NC score	0.699301 (rank : 22)	θ value	3.41135e-07 (rank : 37)
Query Neighborhood Hits	150	Target Neighborhood Hits	162	Shared Neighborhood Hits	72
SwissProt Accessions	Q70EK9, Q8IWJ8	Gene names	USP51
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 51 (EC 3.1.2.15) (Ubiquitin thioesterase 51) (Ubiquitin-specific-processing protease 51) (Deubiquitinating enzyme 51).

UBP44_HUMAN
NC score	0.690967 (rank : 23)	θ value	1.47974e-10 (rank : 21)
Query Neighborhood Hits	150	Target Neighborhood Hits	91	Shared Neighborhood Hits	69
SwissProt Accessions	Q9H0E7	Gene names	USP44
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.1.2.15) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44) (Deubiquitinating enzyme 44).

UBP49_HUMAN
NC score	0.675131 (rank : 24)	θ value	3.64472e-09 (rank : 29)
Query Neighborhood Hits	150	Target Neighborhood Hits	100	Shared Neighborhood Hits	70
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP49_MOUSE
NC score	0.674604 (rank : 25)	θ value	2.79066e-09 (rank : 28)
Query Neighborhood Hits	150	Target Neighborhood Hits	91	Shared Neighborhood Hits	69
SwissProt Accessions	Q6P9L4	Gene names	Usp49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

UBP11_HUMAN
NC score	0.671024 (rank : 26)	θ value	1.02475e-11 (rank : 18)
Query Neighborhood Hits	150	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	P51784, Q8IUG6, Q9BWE1	Gene names	USP11, UHX1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.1.2.15) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) (Deubiquitinating enzyme 11).

UBP15_MOUSE
NC score	0.669330 (rank : 27)	θ value	5.43371e-13 (rank : 14)
Query Neighborhood Hits	150	Target Neighborhood Hits	88	Shared Neighborhood Hits	69
SwissProt Accessions	Q8R5H1, Q3UL25	Gene names	Usp15
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15).

UBP33_HUMAN
NC score	0.669310 (rank : 28)	θ value	6.87365e-08 (rank : 35)
Query Neighborhood Hits	150	Target Neighborhood Hits	157	Shared Neighborhood Hits	71
SwissProt Accessions	Q8TEY7, Q8TEY6, Q96AV6, Q9H9F0, Q9UPQ5	Gene names	USP33, KIAA1097, VDU1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.1.2.15) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (Deubiquitinating enzyme 33) (VHL-interacting deubiquitinating enzyme 1).

UBP15_HUMAN
NC score	0.668979 (rank : 29)	θ value	5.43371e-13 (rank : 13)
Query Neighborhood Hits	150	Target Neighborhood Hits	92	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y4E8, Q9HCA6, Q9UNP0, Q9Y5B5	Gene names	USP15, KIAA0529
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.1.2.15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15) (Deubiquitinating enzyme 15) (Unph-2) (Unph4).

UBP16_HUMAN
NC score	0.663391 (rank : 30)	θ value	1.43324e-05 (rank : 42)
Query Neighborhood Hits	150	Target Neighborhood Hits	126	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y5T5, Q8NEL3	Gene names	USP16
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.1.2.15) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16) (Deubiquitinating enzyme 16) (Ubiquitin-processing protease UBP-M).

UBP20_HUMAN
NC score	0.661555 (rank : 31)	θ value	6.43352e-06 (rank : 39)
Query Neighborhood Hits	150	Target Neighborhood Hits	113	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y2K6, Q96LG5, Q9UQN8, Q9UQP0	Gene names	USP20, KIAA1003, LSFR3A
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 20 (EC 3.1.2.15) (Ubiquitin thioesterase 20) (Ubiquitin-specific-processing protease 20) (Deubiquitinating enzyme 20).

UBP48_HUMAN
NC score	0.647255 (rank : 32)	θ value	1.63604e-09 (rank : 25)
Query Neighborhood Hits	150	Target Neighborhood Hits	101	Shared Neighborhood Hits	69
SwissProt Accessions	Q86UV5, Q2M3I4, Q5SZI4, Q5T3T5, Q6NX53, Q8N3F6, Q96F64, Q96IQ3, Q9H5N3, Q9H5T7, Q9NUJ6, Q9NXR0	Gene names	USP48
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP48_MOUSE
NC score	0.645152 (rank : 33)	θ value	1.63604e-09 (rank : 26)
Query Neighborhood Hits	150	Target Neighborhood Hits	124	Shared Neighborhood Hits	69
SwissProt Accessions	Q3V0C5, Q3TM39, Q571J9, Q8VDJ1	Gene names	Usp48, Kiaa4202
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.1.2.15) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48) (Deubiquitinating enzyme 48).

UBP4_HUMAN
NC score	0.645034 (rank : 34)	θ value	5.26297e-08 (rank : 33)
Query Neighborhood Hits	150	Target Neighborhood Hits	89	Shared Neighborhood Hits	69
SwissProt Accessions	Q13107, O43452, O43453	Gene names	USP4, UNP, UNPH
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein homolog).

UBP4_MOUSE
NC score	0.643611 (rank : 35)	θ value	5.26297e-08 (rank : 34)
Query Neighborhood Hits	150	Target Neighborhood Hits	90	Shared Neighborhood Hits	69
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

UBP43_MOUSE
NC score	0.618843 (rank : 36)	θ value	1.09739e-05 (rank : 41)
Query Neighborhood Hits	150	Target Neighborhood Hits	130	Shared Neighborhood Hits	70
SwissProt Accessions	Q8BUM9, Q8VDP5	Gene names	Usp43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP18_HUMAN
NC score	0.615357 (rank : 37)	θ value	3.19293e-05 (rank : 45)
Query Neighborhood Hits	150	Target Neighborhood Hits	81	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UMW8, Q9NY71	Gene names	USP18, ISG43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease) (hUBP43).

UBP43_HUMAN
NC score	0.615127 (rank : 38)	θ value	1.43324e-05 (rank : 43)
Query Neighborhood Hits	150	Target Neighborhood Hits	144	Shared Neighborhood Hits	71
SwissProt Accessions	Q70EL4, Q8N2C5, Q96DQ6	Gene names	USP43
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.1.2.15) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43) (Deubiquitinating enzyme 43).

UBP1_HUMAN
NC score	0.611951 (rank : 39)	θ value	3.19293e-05 (rank : 46)
Query Neighborhood Hits	150	Target Neighborhood Hits	259	Shared Neighborhood Hits	74
SwissProt Accessions	O94782, Q9UFR0, Q9UNJ3	Gene names	USP1
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 1 (EC 3.1.2.15) (Ubiquitin thioesterase 1) (Ubiquitin-specific-processing protease 1) (Deubiquitinating enzyme 1) (hUBP).

UBP31_HUMAN
NC score	0.607191 (rank : 40)	θ value	0.00020696 (rank : 49)
Query Neighborhood Hits	150	Target Neighborhood Hits	293	Shared Neighborhood Hits	82
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

UBP14_HUMAN
NC score	0.596021 (rank : 41)	θ value	1.38499e-08 (rank : 30)
Query Neighborhood Hits	150	Target Neighborhood Hits	89	Shared Neighborhood Hits	67
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP14_MOUSE
NC score	0.592282 (rank : 42)	θ value	1.38499e-08 (rank : 31)
Query Neighborhood Hits	150	Target Neighborhood Hits	87	Shared Neighborhood Hits	66
SwissProt Accessions	Q9JMA1, Q543U5, Q923F2, Q9D0L0	Gene names	Usp14
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

UBP7_HUMAN
NC score	0.587265 (rank : 43)	θ value	1.43324e-05 (rank : 44)
Query Neighborhood Hits	150	Target Neighborhood Hits	93	Shared Neighborhood Hits	66
SwissProt Accessions	Q93009	Gene names	USP7, HAUSP
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.1.2.15) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease).

UBP24_HUMAN
NC score	0.567658 (rank : 44)	θ value	0.000602161 (rank : 50)
Query Neighborhood Hits	150	Target Neighborhood Hits	96	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

UBP30_HUMAN
NC score	0.566845 (rank : 45)	θ value	0.0193708 (rank : 60)
Query Neighborhood Hits	150	Target Neighborhood Hits	94	Shared Neighborhood Hits	66
SwissProt Accessions	Q70CQ3, Q8WTU7, Q96JX4, Q9BSS3	Gene names	USP30
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 30 (EC 3.1.2.15) (Ubiquitin thioesterase 30) (Ubiquitin-specific-processing protease 30) (Deubiquitinating enzyme 30).

SNUT2_MOUSE
NC score	0.565106 (rank : 46)	θ value	4.1701e-05 (rank : 47)
Query Neighborhood Hits	150	Target Neighborhood Hits	80	Shared Neighborhood Hits	57
SwissProt Accessions	Q3TIX9, Q3TI55, Q8BLI5, Q8BZZ5, Q9CQR1	Gene names	Usp39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39).

UBP37_HUMAN
NC score	0.550982 (rank : 47)	θ value	1.09739e-05 (rank : 40)
Query Neighborhood Hits	150	Target Neighborhood Hits	208	Shared Neighborhood Hits	69
SwissProt Accessions	Q86T82, Q9HCH8	Gene names	USP37, KIAA1594
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 37 (EC 3.1.2.15) (Ubiquitin thioesterase 37) (Ubiquitin-specific-processing protease 37) (Deubiquitinating enzyme 37).

SNUT2_HUMAN
NC score	0.548050 (rank : 48)	θ value	0.000158464 (rank : 48)
Query Neighborhood Hits	150	Target Neighborhood Hits	79	Shared Neighborhood Hits	55
SwissProt Accessions	Q53GS9, Q6NX47, Q96RK9, Q9BV89, Q9H381, Q9P050, Q9Y310	Gene names	USP39
Domain Architecture	No domain graphic available
Description	U4/U6.U5 tri-snRNP-associated protein 2 (U4/U6.U5 tri-snRNP-associated 65 kDa protein) (65K) (Inactive ubiquitin-specific peptidase 39) (SAD1 homolog).

UBP18_MOUSE
NC score	0.543926 (rank : 49)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	150	Target Neighborhood Hits	77	Shared Neighborhood Hits	65
SwissProt Accessions	Q9WTV6	Gene names	Usp18, Ubp43
Domain Architecture
Description	Ubl carboxyl-terminal hydrolase 18 (EC 3.1.2.-) (Ubl thioesterase 18) (ISG15-specific-processing protease) (43 kDa ISG15-specific protease).

UBP47_MOUSE
NC score	0.542144 (rank : 50)	θ value	0.00102713 (rank : 53)
Query Neighborhood Hits	150	Target Neighborhood Hits	135	Shared Neighborhood Hits	68
SwissProt Accessions	Q8BY87, Q5EBP2, Q6KAR9, Q80V06, Q8BHU1, Q8BI15, Q8BI16, Q8BUW4, Q91X25	Gene names	Usp47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

USP9X_MOUSE
NC score	0.538301 (rank : 51)	θ value	1.80886e-08 (rank : 32)
Query Neighborhood Hits	150	Target Neighborhood Hits	171	Shared Neighborhood Hits	70
SwissProt Accessions	P70398, Q62497	Gene names	Usp9x, Fafl, Fam
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin carboxyl-terminal hydrolase FAM) (Fat facets homolog).

UBP47_HUMAN
NC score	0.538127 (rank : 52)	θ value	0.00390308 (rank : 55)
Query Neighborhood Hits	150	Target Neighborhood Hits	149	Shared Neighborhood Hits	68
SwissProt Accessions	Q96K76, Q658U0, Q86Y73, Q8TEP6, Q9BWI0, Q9NWN1	Gene names	USP47
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.1.2.15) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47) (Deubiquitinating enzyme 47).

USP9X_HUMAN
NC score	0.535439 (rank : 53)	θ value	8.97725e-08 (rank : 36)
Query Neighborhood Hits	150	Target Neighborhood Hits	161	Shared Neighborhood Hits	70
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

USP9Y_HUMAN
NC score	0.530778 (rank : 54)	θ value	1.69304e-06 (rank : 38)
Query Neighborhood Hits	150	Target Neighborhood Hits	109	Shared Neighborhood Hits	69
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

UBP35_HUMAN
NC score	0.524328 (rank : 55)	θ value	0.0148317 (rank : 58)
Query Neighborhood Hits	150	Target Neighborhood Hits	223	Shared Neighborhood Hits	70
SwissProt Accessions	Q9P2H5	Gene names	USP35, KIAA1372, USP34
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 35 (EC 3.1.2.15) (Ubiquitin thioesterase 35) (Ubiquitin-specific-processing protease 35) (Deubiquitinating enzyme 35).

UBP32_HUMAN
NC score	0.523349 (rank : 56)	θ value	0.0563607 (rank : 64)
Query Neighborhood Hits	150	Target Neighborhood Hits	170	Shared Neighborhood Hits	71
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

UBP40_HUMAN
NC score	0.511225 (rank : 57)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	150	Target Neighborhood Hits	81	Shared Neighborhood Hits	67
SwissProt Accessions	Q9NVE5, Q6NX38, Q70EL0	Gene names	USP40
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.1.2.15) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40) (Deubiquitinating enzyme 40).

UBP6_HUMAN
NC score	0.496556 (rank : 58)	θ value	0.0736092 (rank : 68)
Query Neighborhood Hits	150	Target Neighborhood Hits	188	Shared Neighborhood Hits	73
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

UBP29_HUMAN
NC score	0.493668 (rank : 59)	θ value	0.00390308 (rank : 54)
Query Neighborhood Hits	150	Target Neighborhood Hits	94	Shared Neighborhood Hits	67
SwissProt Accessions	Q9HBJ7	Gene names	USP29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP38_HUMAN
NC score	0.492363 (rank : 60)	θ value	0.0330416 (rank : 62)
Query Neighborhood Hits	150	Target Neighborhood Hits	97	Shared Neighborhood Hits	67
SwissProt Accessions	Q8NB14, Q8NDF5, Q96DK6, Q96PZ6, Q9BY55	Gene names	USP38, KIAA1891
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38) (HP43.8KD).

UBP26_HUMAN
NC score	0.484729 (rank : 61)	θ value	0.00102713 (rank : 52)
Query Neighborhood Hits	150	Target Neighborhood Hits	108	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BXU7	Gene names	USP26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP38_MOUSE
NC score	0.477954 (rank : 62)	θ value	0.62314 (rank : 83)
Query Neighborhood Hits	150	Target Neighborhood Hits	100	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BW70, Q8BWL1, Q8BX03	Gene names	Usp38
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.1.2.15) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38) (Deubiquitinating enzyme 38).

UBP29_MOUSE
NC score	0.470823 (rank : 63)	θ value	0.0113563 (rank : 56)
Query Neighborhood Hits	150	Target Neighborhood Hits	95	Shared Neighborhood Hits	67
SwissProt Accessions	Q9ES63	Gene names	Usp29
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 29 (EC 3.1.2.15) (Ubiquitin thioesterase 29) (Ubiquitin-specific-processing protease 29) (Deubiquitinating enzyme 29).

UBP34_HUMAN
NC score	0.441461 (rank : 64)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	150	Target Neighborhood Hits	210	Shared Neighborhood Hits	71
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_MOUSE
NC score	0.441285 (rank : 65)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	150	Target Neighborhood Hits	189	Shared Neighborhood Hits	71
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP26_MOUSE
NC score	0.436234 (rank : 66)	θ value	0.000786445 (rank : 51)
Query Neighborhood Hits	150	Target Neighborhood Hits	107	Shared Neighborhood Hits	69
SwissProt Accessions	Q99MX1	Gene names	Usp26
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.1.2.15) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26) (Deubiquitinating enzyme 26).

UBP5_HUMAN
NC score	0.423973 (rank : 67)	θ value	0.0252991 (rank : 61)
Query Neighborhood Hits	150	Target Neighborhood Hits	109	Shared Neighborhood Hits	70
SwissProt Accessions	P45974, Q96J22	Gene names	USP5, ISOT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP5_MOUSE
NC score	0.415108 (rank : 68)	θ value	0.0736092 (rank : 67)
Query Neighborhood Hits	150	Target Neighborhood Hits	106	Shared Neighborhood Hits	70
SwissProt Accessions	P56399	Gene names	Usp5, Isot
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 5 (EC 3.1.2.15) (Ubiquitin thioesterase 5) (Ubiquitin-specific-processing protease 5) (Deubiquitinating enzyme 5) (Isopeptidase T).

UBP13_HUMAN
NC score	0.406520 (rank : 69)	θ value	0.0563607 (rank : 63)
Query Neighborhood Hits	150	Target Neighborhood Hits	99	Shared Neighborhood Hits	69
SwissProt Accessions	Q92995	Gene names	USP13, ISOT3
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.1.2.15) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3).

UBP25_HUMAN
NC score	0.297859 (rank : 70)	θ value	0.0736092 (rank : 66)
Query Neighborhood Hits	150	Target Neighborhood Hits	124	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UHP3, Q9H9W1	Gene names	USP25, USP21
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (USP on chromosome 21).

UBP28_HUMAN
NC score	0.296849 (rank : 71)	θ value	2.36792 (rank : 104)
Query Neighborhood Hits	150	Target Neighborhood Hits	117	Shared Neighborhood Hits	68
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP28_MOUSE
NC score	0.292529 (rank : 72)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	150	Target Neighborhood Hits	178	Shared Neighborhood Hits	70
SwissProt Accessions	Q5I043, Q6NZP3, Q6ZPP1, Q8BWI1	Gene names	Usp28, Kiaa1515
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

UBP25_MOUSE
NC score	0.288665 (rank : 73)	θ value	1.38821 (rank : 94)
Query Neighborhood Hits	150	Target Neighborhood Hits	116	Shared Neighborhood Hits	68
SwissProt Accessions	P57080, Q80ZT9	Gene names	Usp25
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.1.2.15) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25) (Deubiquitinating enzyme 25) (mUSP25).

BRAP_MOUSE
NC score	0.086237 (rank : 74)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	150	Target Neighborhood Hits	409	Shared Neighborhood Hits	19
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

GGNB1_MOUSE
NC score	0.078273 (rank : 75)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	150	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	Q6K1E7, Q8C5T9	Gene names	Ggnbp1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

BRAP_HUMAN
NC score	0.074548 (rank : 76)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	150	Target Neighborhood Hits	560	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BASP_HUMAN
NC score	0.068600 (rank : 77)	θ value	0.0148317 (rank : 57)
Query Neighborhood Hits	150	Target Neighborhood Hits	321	Shared Neighborhood Hits	17
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

GGNB1_HUMAN
NC score	0.062788 (rank : 78)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	150	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	Q5YKI7, Q5YKI8	Gene names	GGNBP1
Domain Architecture	No domain graphic available
Description	Gametogenetin-binding protein 1.

HDAC6_MOUSE
NC score	0.060666 (rank : 79)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	150	Target Neighborhood Hits	88	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Z2V5	Gene names	Hdac6
Domain Architecture
Description	Histone deacetylase 6 (HD6) (Histone deacetylase mHDA2).

HDAC6_HUMAN
NC score	0.058105 (rank : 80)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	150	Target Neighborhood Hits	145	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UBN7	Gene names	HDAC6
Domain Architecture
Description	Histone deacetylase 6 (HD6).

AP180_HUMAN
NC score	0.055674 (rank : 81)	θ value	0.21417 (rank : 72)
Query Neighborhood Hits	150	Target Neighborhood Hits	183	Shared Neighborhood Hits	12
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

BASP_MOUSE
NC score	0.050824 (rank : 82)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	150	Target Neighborhood Hits	260	Shared Neighborhood Hits	18
SwissProt Accessions	Q91XV3	Gene names	Basp1, Nap22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

AP180_MOUSE
NC score	0.048232 (rank : 83)	θ value	1.06291 (rank : 87)
Query Neighborhood Hits	150	Target Neighborhood Hits	194	Shared Neighborhood Hits	12
SwissProt Accessions	Q61548, Q61547	Gene names	Snap91
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein) (Phosphoprotein F1- 20).

NACAM_MOUSE
NC score	0.047925 (rank : 84)	θ value	0.125558 (rank : 69)
Query Neighborhood Hits	150	Target Neighborhood Hits	1866	Shared Neighborhood Hits	56
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TGON2_HUMAN
NC score	0.046320 (rank : 85)	θ value	0.813845 (rank : 86)
Query Neighborhood Hits	150	Target Neighborhood Hits	1037	Shared Neighborhood Hits	44
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

RD23B_HUMAN
NC score	0.045129 (rank : 86)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	150	Target Neighborhood Hits	115	Shared Neighborhood Hits	13
SwissProt Accessions	P54727, Q8WUB0	Gene names	RAD23B
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (hHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

NFRKB_MOUSE
NC score	0.042238 (rank : 87)	θ value	0.47712 (rank : 80)
Query Neighborhood Hits	150	Target Neighborhood Hits	393	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

OKL38_HUMAN
NC score	0.040523 (rank : 88)	θ value	0.365318 (rank : 75)
Query Neighborhood Hits	150	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJX0, Q86UQ1, Q96S88, Q9BZ70	Gene names	OKL38
Domain Architecture
Description	Pregnancy-induced growth inhibitor OKL38 (huOKL38) (Ovary, kidney and liver protein 38).

NU214_HUMAN
NC score	0.039742 (rank : 89)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	150	Target Neighborhood Hits	657	Shared Neighborhood Hits	24
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

MUC7_HUMAN
NC score	0.037748 (rank : 90)	θ value	0.813845 (rank : 84)
Query Neighborhood Hits	150	Target Neighborhood Hits	538	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

NFRKB_HUMAN
NC score	0.036774 (rank : 91)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	150	Target Neighborhood Hits	211	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

MAGE1_HUMAN
NC score	0.036514 (rank : 92)	θ value	0.47712 (rank : 79)
Query Neighborhood Hits	150	Target Neighborhood Hits	1389	Shared Neighborhood Hits	46
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

CJ030_MOUSE
NC score	0.036353 (rank : 93)	θ value	0.47712 (rank : 76)
Query Neighborhood Hits	150	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BSV3, Q4VAD9, Q6PHN3, Q8BPJ4, Q8C973	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C10orf30 homolog.

NFH_MOUSE
NC score	0.035488 (rank : 94)	θ value	0.0736092 (rank : 65)
Query Neighborhood Hits	150	Target Neighborhood Hits	2247	Shared Neighborhood Hits	67
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MAP4_MOUSE
NC score	0.034179 (rank : 95)	θ value	1.81305 (rank : 97)
Query Neighborhood Hits	150	Target Neighborhood Hits	409	Shared Neighborhood Hits	26
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

SRRM2_MOUSE
NC score	0.033277 (rank : 96)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	150	Target Neighborhood Hits	1470	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PKHA6_HUMAN
NC score	0.031409 (rank : 97)	θ value	1.06291 (rank : 89)
Query Neighborhood Hits	150	Target Neighborhood Hits	556	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

MINT_MOUSE
NC score	0.030200 (rank : 98)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	150	Target Neighborhood Hits	1514	Shared Neighborhood Hits	47
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

X3CL1_HUMAN
NC score	0.029056 (rank : 99)	θ value	1.06291 (rank : 90)
Query Neighborhood Hits	150	Target Neighborhood Hits	152	Shared Neighborhood Hits	9
SwissProt Accessions	P78423, O00672	Gene names	CX3CL1, A-152E5.2, FKN, NTT, SCYD1
Domain Architecture
Description	Fractalkine precursor (CX3CL1) (Neurotactin) (CX3C membrane-anchored chemokine) (Small inducible cytokine D1).

RBBP6_MOUSE
NC score	0.028678 (rank : 100)	θ value	1.38821 (rank : 93)
Query Neighborhood Hits	150	Target Neighborhood Hits	1014	Shared Neighborhood Hits	24
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

K0460_MOUSE
NC score	0.027624 (rank : 101)	θ value	1.81305 (rank : 96)
Query Neighborhood Hits	150	Target Neighborhood Hits	374	Shared Neighborhood Hits	21
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

RBM19_MOUSE
NC score	0.027602 (rank : 102)	θ value	0.0193708 (rank : 59)
Query Neighborhood Hits	150	Target Neighborhood Hits	296	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

PKHA6_MOUSE
NC score	0.026924 (rank : 103)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	150	Target Neighborhood Hits	591	Shared Neighborhood Hits	19
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

BSN_HUMAN
NC score	0.026588 (rank : 104)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	150	Target Neighborhood Hits	1537	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

BSN_MOUSE
NC score	0.026473 (rank : 105)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	150	Target Neighborhood Hits	2057	Shared Neighborhood Hits	55
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

THAP8_HUMAN
NC score	0.026216 (rank : 106)	θ value	2.36792 (rank : 103)
Query Neighborhood Hits	150	Target Neighborhood Hits	35	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NA92, Q96M21	Gene names	THAP8
Domain Architecture
Description	THAP domain-containing protein 8.

RERE_MOUSE
NC score	0.026176 (rank : 107)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	150	Target Neighborhood Hits	785	Shared Neighborhood Hits	28
SwissProt Accessions	Q80TZ9	Gene names	Rere, Atr2, Kiaa0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-2).

CIZ1_HUMAN
NC score	0.026030 (rank : 108)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	150	Target Neighborhood Hits	359	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

RERE_HUMAN
NC score	0.024727 (rank : 109)	θ value	3.0926 (rank : 113)
Query Neighborhood Hits	150	Target Neighborhood Hits	779	Shared Neighborhood Hits	22
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

EVL_MOUSE
NC score	0.023208 (rank : 110)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	150	Target Neighborhood Hits	203	Shared Neighborhood Hits	18
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

SRRM2_HUMAN
NC score	0.022684 (rank : 111)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	150	Target Neighborhood Hits	1296	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

MAP1B_HUMAN
NC score	0.022531 (rank : 112)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	150	Target Neighborhood Hits	903	Shared Neighborhood Hits	25
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

NFH_HUMAN
NC score	0.022152 (rank : 113)	θ value	0.125558 (rank : 70)
Query Neighborhood Hits	150	Target Neighborhood Hits	1242	Shared Neighborhood Hits	33
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

HCN1_HUMAN
NC score	0.021725 (rank : 114)	θ value	0.279714 (rank : 74)
Query Neighborhood Hits	150	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	O60741	Gene names	HCN1, BCNG1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1).

FMN2_HUMAN
NC score	0.021701 (rank : 115)	θ value	1.06291 (rank : 88)
Query Neighborhood Hits	150	Target Neighborhood Hits	484	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZ56, Q59GF6, Q5VU37, Q9NZ55	Gene names	FMN2
Domain Architecture	No domain graphic available
Description	Formin-2.

INT1_MOUSE
NC score	0.021522 (rank : 116)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	150	Target Neighborhood Hits	44	Shared Neighborhood Hits	6
SwissProt Accessions	Q6P4S8, Q80UQ7, Q91Z01, Q9CTF7	Gene names	Ints1
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 1 (Int1).

HSP74_MOUSE
NC score	0.021122 (rank : 117)	θ value	0.163984 (rank : 71)
Query Neighborhood Hits	150	Target Neighborhood Hits	257	Shared Neighborhood Hits	7
SwissProt Accessions	Q61316	Gene names	Hspa4, Hsp110
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2).

HCN1_MOUSE
NC score	0.020935 (rank : 118)	θ value	0.47712 (rank : 77)
Query Neighborhood Hits	150	Target Neighborhood Hits	172	Shared Neighborhood Hits	8
SwissProt Accessions	O88704, O54899, Q9D613	Gene names	Hcn1, Bcng1, Hac2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2).

MAP1B_MOUSE
NC score	0.020021 (rank : 119)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	150	Target Neighborhood Hits	977	Shared Neighborhood Hits	29
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

TIAM1_MOUSE
NC score	0.018540 (rank : 120)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	150	Target Neighborhood Hits	205	Shared Neighborhood Hits	6
SwissProt Accessions	Q60610	Gene names	Tiam1, Tiam-1
Domain Architecture
Description	T-lymphoma invasion and metastasis-inducing protein 1 (TIAM-1 protein).

ASXL1_MOUSE
NC score	0.018339 (rank : 121)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	150	Target Neighborhood Hits	182	Shared Neighborhood Hits	15
SwissProt Accessions	P59598	Gene names	Asxl1, Kiaa0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

HSP74_HUMAN
NC score	0.016758 (rank : 122)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	150	Target Neighborhood Hits	154	Shared Neighborhood Hits	8
SwissProt Accessions	P34932, O95756	Gene names	HSPA4
Domain Architecture
Description	Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) (HSP70RY).

RANB3_HUMAN
NC score	0.016573 (rank : 123)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	150	Target Neighborhood Hits	117	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H6Z4, O60405, O75759, O75760, Q9BT47, Q9UG74	Gene names	RANBP3
Domain Architecture	No domain graphic available
Description	Ran-binding protein 3 (RanBP3).

GPR98_HUMAN
NC score	0.016156 (rank : 124)	θ value	1.38821 (rank : 91)
Query Neighborhood Hits	150	Target Neighborhood Hits	202	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXG9, O75171, Q9H0X5, Q9UL61	Gene names	GPR98, KIAA0686, MASS1, VLGR1
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor 98 precursor (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Very large G-protein coupled receptor 1) (Usher syndrome type-2C protein).

ANC5_HUMAN
NC score	0.016079 (rank : 125)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	150	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJX4, Q8N4H7, Q9BQD4	Gene names	ANAPC5, APC5
Domain Architecture	No domain graphic available
Description	Anaphase-promoting complex subunit 5 (APC5) (Cyclosome subunit 5).

OXA1L_HUMAN
NC score	0.015437 (rank : 126)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	150	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q15070	Gene names	OXA1L
Domain Architecture
Description	Inner membrane protein OXA1L, mitochondrial precursor (Oxidase assembly 1-like protein) (OXA1-like protein) (OXA1Hs) (Hsa).

LDB3_MOUSE
NC score	0.015162 (rank : 127)	θ value	0.47712 (rank : 78)
Query Neighborhood Hits	150	Target Neighborhood Hits	510	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

PK3C3_MOUSE
NC score	0.014134 (rank : 128)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	150	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PF93, Q8R3S8	Gene names	Pik3c3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3).

SYNJ1_MOUSE
NC score	0.013986 (rank : 129)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	150	Target Neighborhood Hits	516	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

PO2F1_MOUSE
NC score	0.013480 (rank : 130)	θ value	0.813845 (rank : 85)
Query Neighborhood Hits	150	Target Neighborhood Hits	408	Shared Neighborhood Hits	13
SwissProt Accessions	P25425, Q61994, Q63891, Q6Y681, Q7TSD0, Q8BT04, Q8K570, Q99JH0, Q9WTZ4, Q9WTZ5, Q9WTZ6	Gene names	Pou2f1, Oct-1, Otf-1, Otf1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

TBX6_HUMAN
NC score	0.012917 (rank : 131)	θ value	0.47712 (rank : 81)
Query Neighborhood Hits	150	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	O95947, Q8TAS4	Gene names	TBX6
Domain Architecture
Description	T-box transcription factor TBX6 (T-box protein 6).

IL4RA_MOUSE
NC score	0.012786 (rank : 132)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	150	Target Neighborhood Hits	194	Shared Neighborhood Hits	12
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

TBCD4_MOUSE
NC score	0.011908 (rank : 133)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	150	Target Neighborhood Hits	276	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

SAPS2_HUMAN
NC score	0.011259 (rank : 134)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	150	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	O75170, Q9UGB9	Gene names	SAPS2, KIAA0685
Domain Architecture
Description	SAPS domain family member 2.

PK3C3_HUMAN
NC score	0.010843 (rank : 135)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	150	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NEB9, Q15134	Gene names	PIK3C3
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC 2.7.1.137) (PtdIns-3-kinase type 3) (PI3-kinase type 3) (PI3K type 3) (Phosphoinositide-3-kinase class 3) (Phosphatidylinositol 3-kinase p100 subunit).

TENS1_HUMAN
NC score	0.010044 (rank : 136)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	150	Target Neighborhood Hits	400	Shared Neighborhood Hits	13
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

GNAS1_MOUSE
NC score	0.009601 (rank : 137)	θ value	3.0926 (rank : 111)
Query Neighborhood Hits	150	Target Neighborhood Hits	651	Shared Neighborhood Hits	20
SwissProt Accessions	Q6R0H7, Q6R0H4, Q6R0H5, Q6R2J5, Q9JJX0, Q9Z1N8	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas (Adenylate cyclase-stimulating G alpha protein) (Extra large alphas protein) (XLalphas).

AMOT_HUMAN
NC score	0.009524 (rank : 138)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	150	Target Neighborhood Hits	712	Shared Neighborhood Hits	17
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

DDX24_HUMAN
NC score	0.009318 (rank : 139)	θ value	1.81305 (rank : 95)
Query Neighborhood Hits	150	Target Neighborhood Hits	190	Shared Neighborhood Hits	10
SwissProt Accessions	Q9GZR7	Gene names	DDX24
Domain Architecture
Description	ATP-dependent RNA helicase DDX24 (EC 3.6.1.-) (DEAD box protein 24).

FGD5_MOUSE
NC score	0.009173 (rank : 140)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	150	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	Q80UZ0, Q8BHM5	Gene names	Fgd5
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5.

NCA11_MOUSE
NC score	0.008723 (rank : 141)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	150	Target Neighborhood Hits	661	Shared Neighborhood Hits	20
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

DDX51_HUMAN
NC score	0.007891 (rank : 142)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	150	Target Neighborhood Hits	332	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

LAP4_MOUSE
NC score	0.007786 (rank : 143)	θ value	1.38821 (rank : 92)
Query Neighborhood Hits	150	Target Neighborhood Hits	590	Shared Neighborhood Hits	11
SwissProt Accessions	Q80U72, Q6P5H7, Q7TPH8, Q80VB1, Q8CI48, Q8VII1, Q922S3	Gene names	Scrib, Kiaa0147, Lap4, Scrib1
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog).

RUFY2_HUMAN
NC score	0.007755 (rank : 144)	θ value	1.81305 (rank : 98)
Query Neighborhood Hits	150	Target Neighborhood Hits	1208	Shared Neighborhood Hits	20
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

CENPB_HUMAN
NC score	0.007742 (rank : 145)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	150	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	P07199	Gene names	CENPB
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

LAP4_HUMAN
NC score	0.007232 (rank : 146)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	150	Target Neighborhood Hits	608	Shared Neighborhood Hits	14
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

RUFY2_MOUSE
NC score	0.007208 (rank : 147)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	150	Target Neighborhood Hits	820	Shared Neighborhood Hits	12
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

ELK4_HUMAN
NC score	0.006305 (rank : 148)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	150	Target Neighborhood Hits	184	Shared Neighborhood Hits	11
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

CUL4B_HUMAN
NC score	0.006017 (rank : 149)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	150	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q13620, Q6PIE4, Q6UP07, Q7Z673, Q9BY37, Q9UEB7, Q9UED7	Gene names	CUL4B, KIAA0695
Domain Architecture
Description	Cullin-4B (CUL-4B).

BICD2_MOUSE
NC score	0.005661 (rank : 150)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	150	Target Neighborhood Hits	864	Shared Neighborhood Hits	18
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BICD2_HUMAN
NC score	0.005206 (rank : 151)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	150	Target Neighborhood Hits	856	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TD16, O75181, Q5TBQ2, Q5TBQ3, Q96LH2, Q9BT84, Q9H561	Gene names	BICD2, KIAA0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

SLIK6_MOUSE
NC score	0.004746 (rank : 152)	θ value	1.81305 (rank : 99)
Query Neighborhood Hits	150	Target Neighborhood Hits	302	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C110, Q8BLL0	Gene names	Slitrk6, Sltk6
Domain Architecture
Description	SLIT and NTRK-like protein 6 precursor.

SREC_HUMAN
NC score	0.003138 (rank : 153)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	150	Target Neighborhood Hits	645	Shared Neighborhood Hits	7
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

ZN592_MOUSE
NC score	0.002677 (rank : 154)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	150	Target Neighborhood Hits	768	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BHZ4, Q80XM1	Gene names	Znf592, Kiaa0211, Zfp592
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592 (Zfp-592).

ZN592_HUMAN
NC score	0.001549 (rank : 155)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	150	Target Neighborhood Hits	762	Shared Neighborhood Hits	11
SwissProt Accessions	Q92610	Gene names	ZNF592, KIAA0211
Domain Architecture	No domain graphic available
Description	Zinc finger protein 592.

LATS1_MOUSE
NC score	-0.000148 (rank : 156)	θ value	3.0926 (rank : 112)
Query Neighborhood Hits	150	Target Neighborhood Hits	1027	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

CD2L2_HUMAN
NC score	-0.001840 (rank : 157)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	150	Target Neighborhood Hits	1439	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

ABL1_MOUSE
NC score	-0.002546 (rank : 158)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	150	Target Neighborhood Hits	1178	Shared Neighborhood Hits	18
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ZN335_HUMAN
NC score	-0.002669 (rank : 159)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	150	Target Neighborhood Hits	973	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

KCC2B_HUMAN
NC score	-0.004346 (rank : 160)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	150	Target Neighborhood Hits	866	Shared Neighborhood Hits	8
SwissProt Accessions	Q13554, O95437, O95438, O95599, Q9UGH7, Q9UGH8, Q9UGH9, Q9UNX0, Q9UNX7, Q9UP00, Q9Y5N4, Q9Y6F4	Gene names	CAMK2B, CAM2, CAMKB
Domain Architecture
Description	Calcium/calmodulin-dependent protein kinase type II beta chain (EC 2.7.11.17) (CaM-kinase II beta chain) (CaM kinase II subunit beta) (CaMK-II subunit beta).