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Network neighborhood for query Sequence : KCNK4_MOUSE

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KCNK4_MOUSE
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

KCNK4_MOUSE
θ value	8.84838e-173 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	118	Target Neighborhood Hits	118	Shared Neighborhood Hits	118
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KCNK4_HUMAN
θ value	3.28708e-135 (rank : 2)	NC score	0.984754 (rank : 2)
Query Neighborhood Hits	118	Target Neighborhood Hits	109	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK2_MOUSE
θ value	3.12697e-77 (rank : 3)	NC score	0.963420 (rank : 3)
Query Neighborhood Hits	118	Target Neighborhood Hits	88	Shared Neighborhood Hits	63
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK2_HUMAN
θ value	5.8972e-76 (rank : 4)	NC score	0.963271 (rank : 4)
Query Neighborhood Hits	118	Target Neighborhood Hits	86	Shared Neighborhood Hits	62
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNKA_HUMAN
θ value	2.4834e-66 (rank : 5)	NC score	0.953985 (rank : 5)
Query Neighborhood Hits	118	Target Neighborhood Hits	111	Shared Neighborhood Hits	68
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNK5_HUMAN
θ value	4.13158e-37 (rank : 6)	NC score	0.926790 (rank : 7)
Query Neighborhood Hits	118	Target Neighborhood Hits	102	Shared Neighborhood Hits	66
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

KCNKG_HUMAN
θ value	3.86705e-35 (rank : 7)	NC score	0.942563 (rank : 6)
Query Neighborhood Hits	118	Target Neighborhood Hits	90	Shared Neighborhood Hits	68
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNKH_HUMAN
θ value	1.28732e-30 (rank : 8)	NC score	0.919199 (rank : 8)
Query Neighborhood Hits	118	Target Neighborhood Hits	89	Shared Neighborhood Hits	64
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KCNK6_HUMAN
θ value	4.89182e-30 (rank : 9)	NC score	0.896030 (rank : 9)
Query Neighborhood Hits	118	Target Neighborhood Hits	79	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNK3_MOUSE
θ value	3.62785e-25 (rank : 10)	NC score	0.848998 (rank : 16)
Query Neighborhood Hits	118	Target Neighborhood Hits	93	Shared Neighborhood Hits	67
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK1_HUMAN
θ value	2.35151e-24 (rank : 11)	NC score	0.874501 (rank : 10)
Query Neighborhood Hits	118	Target Neighborhood Hits	68	Shared Neighborhood Hits	56
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

KCNK3_HUMAN
θ value	5.23862e-24 (rank : 12)	NC score	0.849493 (rank : 15)
Query Neighborhood Hits	118	Target Neighborhood Hits	88	Shared Neighborhood Hits	64
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK9_HUMAN
θ value	8.93572e-24 (rank : 13)	NC score	0.853804 (rank : 13)
Query Neighborhood Hits	118	Target Neighborhood Hits	86	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCNK9_MOUSE
θ value	8.93572e-24 (rank : 14)	NC score	0.858395 (rank : 12)
Query Neighborhood Hits	118	Target Neighborhood Hits	86	Shared Neighborhood Hits	63
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

KCNK1_MOUSE
θ value	1.16704e-23 (rank : 15)	NC score	0.872193 (rank : 11)
Query Neighborhood Hits	118	Target Neighborhood Hits	70	Shared Neighborhood Hits	54
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

KCNKF_HUMAN
θ value	2.69047e-20 (rank : 16)	NC score	0.853658 (rank : 14)
Query Neighborhood Hits	118	Target Neighborhood Hits	87	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNKD_MOUSE
θ value	6.85773e-16 (rank : 17)	NC score	0.790999 (rank : 20)
Query Neighborhood Hits	118	Target Neighborhood Hits	51	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R1P5	Gene names	Kcnk13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KCNKD_HUMAN
θ value	2.60593e-15 (rank : 18)	NC score	0.783818 (rank : 21)
Query Neighborhood Hits	118	Target Neighborhood Hits	58	Shared Neighborhood Hits	44
SwissProt Accessions	Q9HB14, Q96E79	Gene names	KCNK13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KCNKC_HUMAN
θ value	3.76295e-14 (rank : 19)	NC score	0.795262 (rank : 19)
Query Neighborhood Hits	118	Target Neighborhood Hits	51	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

KCNK7_MOUSE
θ value	1.2105e-12 (rank : 20)	NC score	0.819799 (rank : 17)
Query Neighborhood Hits	118	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCNK7_HUMAN
θ value	1.80886e-08 (rank : 21)	NC score	0.803023 (rank : 18)
Query Neighborhood Hits	118	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCMA1_HUMAN
θ value	0.00298849 (rank : 22)	NC score	0.203466 (rank : 23)
Query Neighborhood Hits	118	Target Neighborhood Hits	96	Shared Neighborhood Hits	54
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCMA1_MOUSE
θ value	0.00298849 (rank : 23)	NC score	0.203763 (rank : 22)
Query Neighborhood Hits	118	Target Neighborhood Hits	94	Shared Neighborhood Hits	54
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCNH5_HUMAN
θ value	0.0252991 (rank : 24)	NC score	0.193867 (rank : 24)
Query Neighborhood Hits	118	Target Neighborhood Hits	99	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH5_MOUSE
θ value	0.0252991 (rank : 25)	NC score	0.193814 (rank : 25)
Query Neighborhood Hits	118	Target Neighborhood Hits	102	Shared Neighborhood Hits	49
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

OGFR_HUMAN
θ value	0.0431538 (rank : 26)	NC score	0.034196 (rank : 103)
Query Neighborhood Hits	118	Target Neighborhood Hits	1582	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MYRIP_HUMAN
θ value	0.0563607 (rank : 27)	NC score	0.037095 (rank : 102)
Query Neighborhood Hits	118	Target Neighborhood Hits	269	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

WNK2_HUMAN
θ value	0.0736092 (rank : 28)	NC score	0.008440 (rank : 130)
Query Neighborhood Hits	118	Target Neighborhood Hits	1407	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

KCNH1_HUMAN
θ value	0.0961366 (rank : 29)	NC score	0.185188 (rank : 28)
Query Neighborhood Hits	118	Target Neighborhood Hits	98	Shared Neighborhood Hits	49
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH1_MOUSE
θ value	0.0961366 (rank : 30)	NC score	0.185399 (rank : 27)
Query Neighborhood Hits	118	Target Neighborhood Hits	94	Shared Neighborhood Hits	51
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

MUC1_HUMAN
θ value	0.0961366 (rank : 31)	NC score	0.017677 (rank : 115)
Query Neighborhood Hits	118	Target Neighborhood Hits	975	Shared Neighborhood Hits	24
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

KCNH4_HUMAN
θ value	0.125558 (rank : 32)	NC score	0.148131 (rank : 38)
Query Neighborhood Hits	118	Target Neighborhood Hits	177	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNH8_HUMAN
θ value	0.125558 (rank : 33)	NC score	0.160256 (rank : 30)
Query Neighborhood Hits	118	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNQ4_HUMAN
θ value	0.125558 (rank : 34)	NC score	0.147490 (rank : 39)
Query Neighborhood Hits	118	Target Neighborhood Hits	136	Shared Neighborhood Hits	54
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCNT1_HUMAN
θ value	0.163984 (rank : 35)	NC score	0.193549 (rank : 26)
Query Neighborhood Hits	118	Target Neighborhood Hits	87	Shared Neighborhood Hits	53
SwissProt Accessions	Q5JUK3, Q9P2C5	Gene names	KCNT1, KIAA1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1 (KCa4.1).

KCNT1_MOUSE
θ value	0.163984 (rank : 36)	NC score	0.183320 (rank : 29)
Query Neighborhood Hits	118	Target Neighborhood Hits	69	Shared Neighborhood Hits	46
SwissProt Accessions	Q6ZPR4, Q8C3E7	Gene names	Kcnt1, Kiaa1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1.

KCNH7_HUMAN
θ value	0.279714 (rank : 37)	NC score	0.158648 (rank : 32)
Query Neighborhood Hits	118	Target Neighborhood Hits	107	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH7_MOUSE
θ value	0.279714 (rank : 38)	NC score	0.156996 (rank : 33)
Query Neighborhood Hits	118	Target Neighborhood Hits	98	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNQ1_HUMAN
θ value	0.279714 (rank : 39)	NC score	0.119950 (rank : 49)
Query Neighborhood Hits	118	Target Neighborhood Hits	99	Shared Neighborhood Hits	49
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ1_MOUSE
θ value	0.279714 (rank : 40)	NC score	0.118875 (rank : 50)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	50
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCND1_HUMAN
θ value	0.365318 (rank : 41)	NC score	0.128531 (rank : 40)
Query Neighborhood Hits	118	Target Neighborhood Hits	160	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCNH2_HUMAN
θ value	0.47712 (rank : 42)	NC score	0.152788 (rank : 35)
Query Neighborhood Hits	118	Target Neighborhood Hits	158	Shared Neighborhood Hits	50
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
θ value	0.47712 (rank : 43)	NC score	0.152683 (rank : 36)
Query Neighborhood Hits	118	Target Neighborhood Hits	165	Shared Neighborhood Hits	49
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCND2_HUMAN
θ value	0.62314 (rank : 44)	NC score	0.127291 (rank : 42)
Query Neighborhood Hits	118	Target Neighborhood Hits	154	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_MOUSE
θ value	0.62314 (rank : 45)	NC score	0.127314 (rank : 41)
Query Neighborhood Hits	118	Target Neighborhood Hits	156	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND3_HUMAN
θ value	0.62314 (rank : 46)	NC score	0.126436 (rank : 45)
Query Neighborhood Hits	118	Target Neighborhood Hits	162	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_MOUSE
θ value	0.62314 (rank : 47)	NC score	0.126484 (rank : 44)
Query Neighborhood Hits	118	Target Neighborhood Hits	162	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCNH6_HUMAN
θ value	0.62314 (rank : 48)	NC score	0.159051 (rank : 31)
Query Neighborhood Hits	118	Target Neighborhood Hits	222	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNQ2_HUMAN
θ value	0.62314 (rank : 49)	NC score	0.123754 (rank : 47)
Query Neighborhood Hits	118	Target Neighborhood Hits	114	Shared Neighborhood Hits	57
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
θ value	0.62314 (rank : 50)	NC score	0.123263 (rank : 48)
Query Neighborhood Hits	118	Target Neighborhood Hits	163	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNB2_HUMAN
θ value	0.813845 (rank : 51)	NC score	0.087966 (rank : 69)
Query Neighborhood Hits	118	Target Neighborhood Hits	212	Shared Neighborhood Hits	55
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

ANR11_HUMAN
θ value	1.06291 (rank : 52)	NC score	0.008395 (rank : 131)
Query Neighborhood Hits	118	Target Neighborhood Hits	1289	Shared Neighborhood Hits	20
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

CS007_MOUSE
θ value	1.06291 (rank : 53)	NC score	0.023724 (rank : 108)
Query Neighborhood Hits	118	Target Neighborhood Hits	464	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

KCNA6_HUMAN
θ value	1.06291 (rank : 54)	NC score	0.099309 (rank : 56)
Query Neighborhood Hits	118	Target Neighborhood Hits	100	Shared Neighborhood Hits	53
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNH3_HUMAN
θ value	1.06291 (rank : 55)	NC score	0.152361 (rank : 37)
Query Neighborhood Hits	118	Target Neighborhood Hits	148	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH3_MOUSE
θ value	1.06291 (rank : 56)	NC score	0.154005 (rank : 34)
Query Neighborhood Hits	118	Target Neighborhood Hits	133	Shared Neighborhood Hits	36
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNS1_HUMAN
θ value	1.06291 (rank : 57)	NC score	0.074211 (rank : 89)
Query Neighborhood Hits	118	Target Neighborhood Hits	116	Shared Neighborhood Hits	43
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

NRAM1_MOUSE
θ value	1.06291 (rank : 58)	NC score	0.048644 (rank : 99)
Query Neighborhood Hits	118	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	P41251	Gene names	Slc11a1, Bcg, Ity, Lsh, Nramp1
Domain Architecture
Description	Natural resistance-associated macrophage protein 1 (NRAMP 1).

CAC1H_MOUSE
θ value	1.38821 (rank : 59)	NC score	0.017882 (rank : 114)
Query Neighborhood Hits	118	Target Neighborhood Hits	230	Shared Neighborhood Hits	28
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

KCND1_MOUSE
θ value	1.38821 (rank : 60)	NC score	0.124644 (rank : 46)
Query Neighborhood Hits	118	Target Neighborhood Hits	165	Shared Neighborhood Hits	68
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

PCLO_MOUSE
θ value	1.38821 (rank : 61)	NC score	0.016059 (rank : 119)
Query Neighborhood Hits	118	Target Neighborhood Hits	2275	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

TOPB1_MOUSE
θ value	1.38821 (rank : 62)	NC score	0.020357 (rank : 111)
Query Neighborhood Hits	118	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

GLIS3_MOUSE
θ value	1.81305 (rank : 63)	NC score	-0.000430 (rank : 145)
Query Neighborhood Hits	118	Target Neighborhood Hits	861	Shared Neighborhood Hits	10
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

KCNN1_HUMAN
θ value	1.81305 (rank : 64)	NC score	0.082353 (rank : 82)
Query Neighborhood Hits	118	Target Neighborhood Hits	125	Shared Neighborhood Hits	49
SwissProt Accessions	Q92952	Gene names	KCNN1, SK
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

KCNN1_MOUSE
θ value	1.81305 (rank : 65)	NC score	0.084871 (rank : 77)
Query Neighborhood Hits	118	Target Neighborhood Hits	117	Shared Neighborhood Hits	51
SwissProt Accessions	Q9EQR3, Q99JA9	Gene names	Kcnn1, Sk1
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

KCNN3_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.077435 (rank : 85)
Query Neighborhood Hits	118	Target Neighborhood Hits	216	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UGI6, O43517	Gene names	KCNN3, K3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa3).

KCNN3_MOUSE
θ value	1.81305 (rank : 67)	NC score	0.076817 (rank : 86)
Query Neighborhood Hits	118	Target Neighborhood Hits	171	Shared Neighborhood Hits	49
SwissProt Accessions	P58391	Gene names	Kcnn3, Sk3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3).

SNPC4_HUMAN
θ value	1.81305 (rank : 68)	NC score	0.022935 (rank : 109)
Query Neighborhood Hits	118	Target Neighborhood Hits	589	Shared Neighborhood Hits	18
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

CJ078_MOUSE
θ value	2.36792 (rank : 69)	NC score	0.027446 (rank : 106)
Query Neighborhood Hits	118	Target Neighborhood Hits	559	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

EPHAA_HUMAN
θ value	2.36792 (rank : 70)	NC score	-0.000619 (rank : 146)
Query Neighborhood Hits	118	Target Neighborhood Hits	960	Shared Neighborhood Hits	8
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

NRAM1_HUMAN
θ value	2.36792 (rank : 71)	NC score	0.049365 (rank : 98)
Query Neighborhood Hits	118	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	P49279	Gene names	SLC11A1, NRAMP, NRAMP1
Domain Architecture
Description	Natural resistance-associated macrophage protein 1 (NRAMP 1).

PPIP2_HUMAN
θ value	2.36792 (rank : 72)	NC score	0.012109 (rank : 123)
Query Neighborhood Hits	118	Target Neighborhood Hits	254	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

APBA2_HUMAN
θ value	3.0926 (rank : 73)	NC score	0.009590 (rank : 128)
Query Neighborhood Hits	118	Target Neighborhood Hits	220	Shared Neighborhood Hits	6
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

KCNF1_HUMAN
θ value	3.0926 (rank : 74)	NC score	0.096716 (rank : 58)
Query Neighborhood Hits	118	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNQ5_HUMAN
θ value	3.0926 (rank : 75)	NC score	0.127181 (rank : 43)
Query Neighborhood Hits	118	Target Neighborhood Hits	163	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCNS2_HUMAN
θ value	3.0926 (rank : 76)	NC score	0.088106 (rank : 67)
Query Neighborhood Hits	118	Target Neighborhood Hits	129	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_MOUSE
θ value	3.0926 (rank : 77)	NC score	0.088044 (rank : 68)
Query Neighborhood Hits	118	Target Neighborhood Hits	130	Shared Neighborhood Hits	52
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

NRAM2_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.041618 (rank : 100)
Query Neighborhood Hits	118	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	P49281, O43288, O60932, Q96J35	Gene names	SLC11A2, NRAMP2
Domain Architecture
Description	Natural resistance-associated macrophage protein 2 (NRAMP 2) (Divalent metal transporter 1) (DMT1).

SON_MOUSE
θ value	3.0926 (rank : 79)	NC score	0.015916 (rank : 120)
Query Neighborhood Hits	118	Target Neighborhood Hits	957	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

IF4B_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.029160 (rank : 105)
Query Neighborhood Hits	118	Target Neighborhood Hits	417	Shared Neighborhood Hits	9
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

IF4B_MOUSE
θ value	4.03905 (rank : 81)	NC score	0.025005 (rank : 107)
Query Neighborhood Hits	118	Target Neighborhood Hits	368	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

KCNS1_MOUSE
θ value	4.03905 (rank : 82)	NC score	0.084294 (rank : 80)
Query Neighborhood Hits	118	Target Neighborhood Hits	114	Shared Neighborhood Hits	52
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

NRAM2_MOUSE
θ value	4.03905 (rank : 83)	NC score	0.040325 (rank : 101)
Query Neighborhood Hits	118	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	P49282, O54903	Gene names	Slc11a2, Nramp2
Domain Architecture
Description	Natural resistance-associated macrophage protein 2 (NRAMP 2).

PRRT3_HUMAN
θ value	4.03905 (rank : 84)	NC score	0.018952 (rank : 113)
Query Neighborhood Hits	118	Target Neighborhood Hits	998	Shared Neighborhood Hits	24
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SRC8_MOUSE
θ value	4.03905 (rank : 85)	NC score	0.006784 (rank : 136)
Query Neighborhood Hits	118	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

STK6_MOUSE
θ value	4.03905 (rank : 86)	NC score	-0.002312 (rank : 147)
Query Neighborhood Hits	118	Target Neighborhood Hits	886	Shared Neighborhood Hits	6
SwissProt Accessions	P97477, O35624, Q91YU4	Gene names	Stk6, Ark1, Aurka, Ayk1, Iak1
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1).

ASPP1_MOUSE
θ value	5.27518 (rank : 87)	NC score	0.010415 (rank : 125)
Query Neighborhood Hits	118	Target Neighborhood Hits	1244	Shared Neighborhood Hits	22
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

BAP1_HUMAN
θ value	5.27518 (rank : 88)	NC score	0.017466 (rank : 117)
Query Neighborhood Hits	118	Target Neighborhood Hits	106	Shared Neighborhood Hits	7
SwissProt Accessions	Q92560, Q6LEM0, Q7Z5E8	Gene names	BAP1, KIAA0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Cerebral protein 6).

BAP1_MOUSE
θ value	5.27518 (rank : 89)	NC score	0.017491 (rank : 116)
Query Neighborhood Hits	118	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	Q99PU7, Q6ZQE6	Gene names	Bap1, Kiaa0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Ubiquitin C-terminal hydrolase X4) (UCH-X4).

INP5E_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.011278 (rank : 124)
Query Neighborhood Hits	118	Target Neighborhood Hits	201	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

KCNA6_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.096493 (rank : 59)
Query Neighborhood Hits	118	Target Neighborhood Hits	106	Shared Neighborhood Hits	51
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNG1_HUMAN
θ value	5.27518 (rank : 92)	NC score	0.082038 (rank : 83)
Query Neighborhood Hits	118	Target Neighborhood Hits	103	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNQ3_HUMAN
θ value	5.27518 (rank : 93)	NC score	0.117603 (rank : 51)
Query Neighborhood Hits	118	Target Neighborhood Hits	114	Shared Neighborhood Hits	53
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
θ value	5.27518 (rank : 94)	NC score	0.117001 (rank : 52)
Query Neighborhood Hits	118	Target Neighborhood Hits	105	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNV2_HUMAN
θ value	5.27518 (rank : 95)	NC score	0.094852 (rank : 61)
Query Neighborhood Hits	118	Target Neighborhood Hits	137	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

MEGF9_MOUSE
θ value	5.27518 (rank : 96)	NC score	0.005967 (rank : 139)
Query Neighborhood Hits	118	Target Neighborhood Hits	896	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

SEPT9_HUMAN
θ value	5.27518 (rank : 97)	NC score	0.006987 (rank : 134)
Query Neighborhood Hits	118	Target Neighborhood Hits	706	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

YIF1A_MOUSE
θ value	5.27518 (rank : 98)	NC score	0.020462 (rank : 110)
Query Neighborhood Hits	118	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q91XB7, Q9CWB2	Gene names	Yif1a
Domain Architecture	No domain graphic available
Description	Protein YIF1A (YIP1-interacting factor homolog A).

BAZ2A_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.014617 (rank : 121)
Query Neighborhood Hits	118	Target Neighborhood Hits	780	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CIKS_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.017230 (rank : 118)
Query Neighborhood Hits	118	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	O43734, Q5R3A3, Q9H5W2, Q9H6Y3, Q9NS14, Q9UG72	Gene names	TRAF3IP2, C6orf4, C6orf5
Domain Architecture	No domain graphic available
Description	Adapter protein CIKS (Connection to IKK and SAPK/JNK) (TRAF3- interacting protein 2) (Nuclear factor NF-kappa-B activator 1) (ACT1).

HSF1_MOUSE
θ value	6.88961 (rank : 101)	NC score	0.009728 (rank : 127)
Query Neighborhood Hits	118	Target Neighborhood Hits	267	Shared Neighborhood Hits	9
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

K1849_MOUSE
θ value	6.88961 (rank : 102)	NC score	0.007746 (rank : 132)
Query Neighborhood Hits	118	Target Neighborhood Hits	335	Shared Neighborhood Hits	8
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

KCNB1_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.086176 (rank : 73)
Query Neighborhood Hits	118	Target Neighborhood Hits	169	Shared Neighborhood Hits	54
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNB1_MOUSE
θ value	6.88961 (rank : 104)	NC score	0.086100 (rank : 75)
Query Neighborhood Hits	118	Target Neighborhood Hits	154	Shared Neighborhood Hits	53
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

L2GL1_HUMAN
θ value	6.88961 (rank : 105)	NC score	0.006566 (rank : 137)
Query Neighborhood Hits	118	Target Neighborhood Hits	64	Shared Neighborhood Hits	5
SwissProt Accessions	Q15334, O00188, Q58F11, Q86UK6	Gene names	LLGL1, HUGL
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 1 (LLGL) (Human homolog to the D-lgl gene) (Hugl-1) (DLG4).

MAP1A_HUMAN
θ value	6.88961 (rank : 106)	NC score	0.009959 (rank : 126)
Query Neighborhood Hits	118	Target Neighborhood Hits	1626	Shared Neighborhood Hits	25
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

SPEG_MOUSE
θ value	6.88961 (rank : 107)	NC score	-0.000241 (rank : 144)
Query Neighborhood Hits	118	Target Neighborhood Hits	1959	Shared Neighborhood Hits	33
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

UBP31_HUMAN
θ value	6.88961 (rank : 108)	NC score	0.006057 (rank : 138)
Query Neighborhood Hits	118	Target Neighborhood Hits	293	Shared Neighborhood Hits	11
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

YIF1A_HUMAN
θ value	6.88961 (rank : 109)	NC score	0.031712 (rank : 104)
Query Neighborhood Hits	118	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	O95070, Q96G83, Q9BVD0	Gene names	YIF1A, 54TM, HYIF1P, YIF1
Domain Architecture	No domain graphic available
Description	Protein YIF1A (YIP1-interacting factor homolog A) (54TMp).

AQP8_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.005630 (rank : 140)
Query Neighborhood Hits	118	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	O94778, Q8IUU3, Q9UIA4	Gene names	AQP8
Domain Architecture
Description	Aquaporin-8 (AQP-8).

CASC3_MOUSE
θ value	8.99809 (rank : 111)	NC score	0.012153 (rank : 122)
Query Neighborhood Hits	118	Target Neighborhood Hits	333	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

CK024_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.019715 (rank : 112)
Query Neighborhood Hits	118	Target Neighborhood Hits	408	Shared Neighborhood Hits	16
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

CSPG5_MOUSE
θ value	8.99809 (rank : 113)	NC score	0.009022 (rank : 129)
Query Neighborhood Hits	118	Target Neighborhood Hits	211	Shared Neighborhood Hits	6
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

HIRA_MOUSE
θ value	8.99809 (rank : 114)	NC score	0.002670 (rank : 142)
Query Neighborhood Hits	118	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q61666, O08845, Q62365	Gene names	Hira, Tuple1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

MAGE1_HUMAN
θ value	8.99809 (rank : 115)	NC score	0.007718 (rank : 133)
Query Neighborhood Hits	118	Target Neighborhood Hits	1389	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

MAST4_HUMAN
θ value	8.99809 (rank : 116)	NC score	0.000752 (rank : 143)
Query Neighborhood Hits	118	Target Neighborhood Hits	1804	Shared Neighborhood Hits	40
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

NFH_MOUSE
θ value	8.99809 (rank : 117)	NC score	0.006952 (rank : 135)
Query Neighborhood Hits	118	Target Neighborhood Hits	2247	Shared Neighborhood Hits	32
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PO6F1_MOUSE
θ value	8.99809 (rank : 118)	NC score	0.002796 (rank : 141)
Query Neighborhood Hits	118	Target Neighborhood Hits	581	Shared Neighborhood Hits	10
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

CNGA2_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.051720 (rank : 94)
Query Neighborhood Hits	118	Target Neighborhood Hits	86	Shared Neighborhood Hits	18
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA3_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.050891 (rank : 95)
Query Neighborhood Hits	118	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

HCN2_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.050601 (rank : 96)
Query Neighborhood Hits	118	Target Neighborhood Hits	369	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HCN2_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.050211 (rank : 97)
Query Neighborhood Hits	118	Target Neighborhood Hits	278	Shared Neighborhood Hits	32
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

KCNA1_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.084624 (rank : 79)
Query Neighborhood Hits	118	Target Neighborhood Hits	104	Shared Neighborhood Hits	49
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNA1_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.084667 (rank : 78)
Query Neighborhood Hits	118	Target Neighborhood Hits	103	Shared Neighborhood Hits	49
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA2_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.090049 (rank : 65)
Query Neighborhood Hits	118	Target Neighborhood Hits	101	Shared Neighborhood Hits	54
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA2_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.089981 (rank : 66)
Query Neighborhood Hits	118	Target Neighborhood Hits	102	Shared Neighborhood Hits	54
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNA3_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.091411 (rank : 64)
Query Neighborhood Hits	118	Target Neighborhood Hits	101	Shared Neighborhood Hits	50
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA3_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.093305 (rank : 63)
Query Neighborhood Hits	118	Target Neighborhood Hits	103	Shared Neighborhood Hits	53
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA4_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.104106 (rank : 55)
Query Neighborhood Hits	118	Target Neighborhood Hits	108	Shared Neighborhood Hits	56
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNA4_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.093386 (rank : 62)
Query Neighborhood Hits	118	Target Neighborhood Hits	98	Shared Neighborhood Hits	50
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA5_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.097901 (rank : 57)
Query Neighborhood Hits	118	Target Neighborhood Hits	124	Shared Neighborhood Hits	55
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNA5_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.095174 (rank : 60)
Query Neighborhood Hits	118	Target Neighborhood Hits	119	Shared Neighborhood Hits	51
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNC1_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.086081 (rank : 76)
Query Neighborhood Hits	118	Target Neighborhood Hits	133	Shared Neighborhood Hits	47
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC1_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.086134 (rank : 74)
Query Neighborhood Hits	118	Target Neighborhood Hits	133	Shared Neighborhood Hits	47
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNC3_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.086639 (rank : 72)
Query Neighborhood Hits	118	Target Neighborhood Hits	256	Shared Neighborhood Hits	56
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC3_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.079120 (rank : 84)
Query Neighborhood Hits	118	Target Neighborhood Hits	173	Shared Neighborhood Hits	49
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNC4_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.086669 (rank : 71)
Query Neighborhood Hits	118	Target Neighborhood Hits	141	Shared Neighborhood Hits	46
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNC4_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.086816 (rank : 70)
Query Neighborhood Hits	118	Target Neighborhood Hits	130	Shared Neighborhood Hits	46
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNG2_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.083384 (rank : 81)
Query Neighborhood Hits	118	Target Neighborhood Hits	83	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNG3_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.064371 (rank : 93)
Query Neighborhood Hits	118	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.064410 (rank : 92)
Query Neighborhood Hits	118	Target Neighborhood Hits	91	Shared Neighborhood Hits	40
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG4_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.071720 (rank : 90)
Query Neighborhood Hits	118	Target Neighborhood Hits	99	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNN2_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.076468 (rank : 88)
Query Neighborhood Hits	118	Target Neighborhood Hits	117	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.076473 (rank : 87)
Query Neighborhood Hits	118	Target Neighborhood Hits	120	Shared Neighborhood Hits	50
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN4_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.115370 (rank : 54)
Query Neighborhood Hits	118	Target Neighborhood Hits	90	Shared Neighborhood Hits	55
SwissProt Accessions	O15554	Gene names	KCNN4, IK1, IKCA1, KCA4, SK4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1) (IKCa1) (Putative Gardos channel).

KCNN4_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.116199 (rank : 53)
Query Neighborhood Hits	118	Target Neighborhood Hits	85	Shared Neighborhood Hits	55
SwissProt Accessions	O89109, Q3U1J8, Q9CY39	Gene names	Kcnn4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1).

KCNS3_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.067178 (rank : 91)
Query Neighborhood Hits	118	Target Neighborhood Hits	125	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

Hits sorted by NC score

KCNK4_MOUSE
NC score	0.999962 (rank : 1)	θ value	8.84838e-173 (rank : 1)
Query Neighborhood Hits	118	Target Neighborhood Hits	118	Shared Neighborhood Hits	118
SwissProt Accessions	O88454	Gene names	Kcnk4, Traak
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK).

KCNK4_HUMAN
NC score	0.984754 (rank : 2)	θ value	3.28708e-135 (rank : 2)
Query Neighborhood Hits	118	Target Neighborhood Hits	109	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NYG8, Q96T94	Gene names	KCNK4, TRAAK
Domain Architecture
Description	Potassium channel subfamily K member 4 (TWIK-related arachidonic acid- stimulated potassium channel protein) (TRAAK) (Two pore K(+) channel KT4.1).

KCNK2_MOUSE
NC score	0.963420 (rank : 3)	θ value	3.12697e-77 (rank : 3)
Query Neighborhood Hits	118	Target Neighborhood Hits	88	Shared Neighborhood Hits	63
SwissProt Accessions	P97438	Gene names	Kcnk2
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (Two-pore potassium channel TPKC1) (TREK-1 K(+) channel subunit).

KCNK2_HUMAN
NC score	0.963271 (rank : 4)	θ value	5.8972e-76 (rank : 4)
Query Neighborhood Hits	118	Target Neighborhood Hits	86	Shared Neighborhood Hits	62
SwissProt Accessions	O95069, Q9UNE3	Gene names	KCNK2, TREK, TREK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 2 (Outward rectifying potassium channel protein TREK-1) (TREK-1 K(+) channel subunit) (Two-pore potassium channel TPKC1).

KCNKA_HUMAN
NC score	0.953985 (rank : 5)	θ value	2.4834e-66 (rank : 5)
Query Neighborhood Hits	118	Target Neighborhood Hits	111	Shared Neighborhood Hits	68
SwissProt Accessions	P57789, Q8TDK7, Q8TDK8, Q9HB59	Gene names	KCNK10, TREK2
Domain Architecture
Description	Potassium channel subfamily K member 10 (Outward rectifying potassium channel protein TREK-2) (TREK-2 K(+) channel subunit).

KCNKG_HUMAN
NC score	0.942563 (rank : 6)	θ value	3.86705e-35 (rank : 7)
Query Neighborhood Hits	118	Target Neighborhood Hits	90	Shared Neighborhood Hits	68
SwissProt Accessions	Q96T55, Q5TCF3, Q9H591	Gene names	KCNK16, TALK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 16 (TWIK-related alkaline pH- activated K(+) channel 1) (2P domain potassium channel Talk-1).

KCNK5_HUMAN
NC score	0.926790 (rank : 7)	θ value	4.13158e-37 (rank : 6)
Query Neighborhood Hits	118	Target Neighborhood Hits	102	Shared Neighborhood Hits	66
SwissProt Accessions	O95279	Gene names	KCNK5, TASK2
Domain Architecture
Description	Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2).

KCNKH_HUMAN
NC score	0.919199 (rank : 8)	θ value	1.28732e-30 (rank : 8)
Query Neighborhood Hits	118	Target Neighborhood Hits	89	Shared Neighborhood Hits	64
SwissProt Accessions	Q96T54, Q5TCF4, Q8TAW4, Q9BXD1, Q9H592	Gene names	KCNK17, TALK2, TASK4
Domain Architecture
Description	Potassium channel subfamily K member 17 (TWIK-related alkaline pH- activated K(+) channel 2) (2P domain potassium channel Talk-2) (TWIK- related acid-sensitive K(+) channel 4) (TASK-4).

KCNK6_HUMAN
NC score	0.896030 (rank : 9)	θ value	4.89182e-30 (rank : 9)
Query Neighborhood Hits	118	Target Neighborhood Hits	79	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y257, Q9HB47	Gene names	KCNK6, TOSS, TWIK2
Domain Architecture
Description	Potassium channel subfamily K member 6 (Inward rectifying potassium channel protein TWIK-2) (TWIK-originated similarity sequence).

KCNK1_HUMAN
NC score	0.874501 (rank : 10)	θ value	2.35151e-24 (rank : 11)
Query Neighborhood Hits	118	Target Neighborhood Hits	68	Shared Neighborhood Hits	56
SwissProt Accessions	O00180, Q13307	Gene names	KCNK1, HOHO1, KCNO1, TWIK1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1) (Potassium channel KCNO1).

KCNK1_MOUSE
NC score	0.872193 (rank : 11)	θ value	1.16704e-23 (rank : 15)
Query Neighborhood Hits	118	Target Neighborhood Hits	70	Shared Neighborhood Hits	54
SwissProt Accessions	O08581	Gene names	Kcnk1
Domain Architecture
Description	Potassium channel subfamily K member 1 (Inward rectifying potassium channel protein TWIK-1).

KCNK9_MOUSE
NC score	0.858395 (rank : 12)	θ value	8.93572e-24 (rank : 14)
Query Neighborhood Hits	118	Target Neighborhood Hits	86	Shared Neighborhood Hits	63
SwissProt Accessions	Q3LS21	Gene names	Kcnk9, Task3
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3).

KCNK9_HUMAN
NC score	0.853804 (rank : 13)	θ value	8.93572e-24 (rank : 13)
Query Neighborhood Hits	118	Target Neighborhood Hits	86	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NPC2, Q2M290, Q540F2	Gene names	KCNK9, TASK3
Domain Architecture
Description	Potassium channel subfamily K member 9 (Acid-sensitive potassium channel protein TASK-3) (TWIK-related acid-sensitive K(+) channel 3) (Two pore potassium channel KT3.2).

KCNKF_HUMAN
NC score	0.853658 (rank : 14)	θ value	2.69047e-20 (rank : 16)
Query Neighborhood Hits	118	Target Neighborhood Hits	87	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H427, Q9HBC8	Gene names	KCNK15, TASK5
Domain Architecture
Description	Potassium channel subfamily K member 15 (Acid-sensitive potassium channel protein TASK-5) (TWIK-related acid-sensitive K(+) channel 5) (Two pore potassium channel KT3.3).

KCNK3_HUMAN
NC score	0.849493 (rank : 15)	θ value	5.23862e-24 (rank : 12)
Query Neighborhood Hits	118	Target Neighborhood Hits	88	Shared Neighborhood Hits	64
SwissProt Accessions	O14649	Gene names	KCNK3, TASK, TASK1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Two pore potassium channel KT3.1).

KCNK3_MOUSE
NC score	0.848998 (rank : 16)	θ value	3.62785e-25 (rank : 10)
Query Neighborhood Hits	118	Target Neighborhood Hits	93	Shared Neighborhood Hits	67
SwissProt Accessions	O35111, O35163	Gene names	Kcnk3, Ctbak, Task, Task1
Domain Architecture
Description	Potassium channel subfamily K member 3 (Acid-sensitive potassium channel protein TASK-1) (TWIK-related acid-sensitive K(+) channel 1) (Cardiac two-pore background K(+) channel) (cTBAK-1) (Two pore potassium channel KT3.1).

KCNK7_MOUSE
NC score	0.819799 (rank : 17)	θ value	1.2105e-12 (rank : 20)
Query Neighborhood Hits	118	Target Neighborhood Hits	53	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z2T1, Q9QXY0, Q9QYE8, Q9R1V1, Q9R242	Gene names	Kcnk7, Dpkch3, Kcnk6, Kcnk8, Knot1
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7 (Putative potassium channel DP3) (Double-pore K(+) channel 3) (Neuromuscular two p domain potassium channel).

KCNK7_HUMAN
NC score	0.803023 (rank : 18)	θ value	1.80886e-08 (rank : 21)
Query Neighborhood Hits	118	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y2U2, Q9Y2U3, Q9Y2U4	Gene names	KCNK7
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 7.

KCNKC_HUMAN
NC score	0.795262 (rank : 19)	θ value	3.76295e-14 (rank : 19)
Query Neighborhood Hits	118	Target Neighborhood Hits	51	Shared Neighborhood Hits	39
SwissProt Accessions	Q9HB15	Gene names	KCNK12
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily K member 12 (Tandem pore domain halothane- inhibited potassium channel 2) (THIK-2).

KCNKD_MOUSE
NC score	0.790999 (rank : 20)	θ value	6.85773e-16 (rank : 17)
Query Neighborhood Hits	118	Target Neighborhood Hits	51	Shared Neighborhood Hits	41
SwissProt Accessions	Q8R1P5	Gene names	Kcnk13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KCNKD_HUMAN
NC score	0.783818 (rank : 21)	θ value	2.60593e-15 (rank : 18)
Query Neighborhood Hits	118	Target Neighborhood Hits	58	Shared Neighborhood Hits	44
SwissProt Accessions	Q9HB14, Q96E79	Gene names	KCNK13
Domain Architecture
Description	Potassium channel subfamily K member 13 (Tandem pore domain halothane- inhibited potassium channel 1) (THIK-1).

KCMA1_MOUSE
NC score	0.203763 (rank : 22)	θ value	0.00298849 (rank : 23)
Query Neighborhood Hits	118	Target Neighborhood Hits	94	Shared Neighborhood Hits	54
SwissProt Accessions	Q08460, Q64703, Q8VHF1, Q9R196	Gene names	Kcnma1, Kcnma
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (mSlo) (mSlo1).

KCMA1_HUMAN
NC score	0.203466 (rank : 23)	θ value	0.00298849 (rank : 22)
Query Neighborhood Hits	118	Target Neighborhood Hits	96	Shared Neighborhood Hits	54
SwissProt Accessions	Q12791, Q12886, Q12917, Q12921, Q12960, Q13150, Q96LG8, Q9UBB0, Q9UQK6	Gene names	KCNMA1, KCNMA
Domain Architecture
Description	Calcium-activated potassium channel subunit alpha 1 (Calcium-activated potassium channel, subfamily M subunit alpha 1) (Maxi K channel) (MaxiK) (BK channel) (K(VCA)alpha) (BKCA alpha) (KCa1.1) (Slowpoke homolog) (Slo homolog) (Slo-alpha) (Slo1) (hSlo).

KCNH5_HUMAN
NC score	0.193867 (rank : 24)	θ value	0.0252991 (rank : 24)
Query Neighborhood Hits	118	Target Neighborhood Hits	99	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NCM2	Gene names	KCNH5, EAG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (hEAG2).

KCNH5_MOUSE
NC score	0.193814 (rank : 25)	θ value	0.0252991 (rank : 25)
Query Neighborhood Hits	118	Target Neighborhood Hits	102	Shared Neighborhood Hits	49
SwissProt Accessions	Q920E3, Q8C035	Gene names	Kcnh5, Eag2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily H member 5 (Voltage-gated potassium channel subunit Kv10.2) (Ether-a-go-go potassium channel 2) (Eag2).

KCNT1_HUMAN
NC score	0.193549 (rank : 26)	θ value	0.163984 (rank : 35)
Query Neighborhood Hits	118	Target Neighborhood Hits	87	Shared Neighborhood Hits	53
SwissProt Accessions	Q5JUK3, Q9P2C5	Gene names	KCNT1, KIAA1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1 (KCa4.1).

KCNH1_MOUSE
NC score	0.185399 (rank : 27)	θ value	0.0961366 (rank : 30)
Query Neighborhood Hits	118	Target Neighborhood Hits	94	Shared Neighborhood Hits	51
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH1_HUMAN
NC score	0.185188 (rank : 28)	θ value	0.0961366 (rank : 29)
Query Neighborhood Hits	118	Target Neighborhood Hits	98	Shared Neighborhood Hits	49
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNT1_MOUSE
NC score	0.183320 (rank : 29)	θ value	0.163984 (rank : 36)
Query Neighborhood Hits	118	Target Neighborhood Hits	69	Shared Neighborhood Hits	46
SwissProt Accessions	Q6ZPR4, Q8C3E7	Gene names	Kcnt1, Kiaa1422
Domain Architecture	No domain graphic available
Description	Potassium channel subfamily T member 1.

KCNH8_HUMAN
NC score	0.160256 (rank : 30)	θ value	0.125558 (rank : 33)
Query Neighborhood Hits	118	Target Neighborhood Hits	104	Shared Neighborhood Hits	40
SwissProt Accessions	Q96L42	Gene names	KCNH8
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 8 (Voltage-gated potassium channel subunit Kv12.1) (Ether-a-go-go-like potassium channel 3) (ELK channel 3) (ELK3) (ELK1) (hElk1).

KCNH6_HUMAN
NC score	0.159051 (rank : 31)	θ value	0.62314 (rank : 48)
Query Neighborhood Hits	118	Target Neighborhood Hits	222	Shared Neighborhood Hits	53
SwissProt Accessions	Q9H252, Q9BRD7	Gene names	KCNH6, ERG2, HERG2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 6 (Voltage-gated potassium channel subunit Kv11.2) (Ether-a-go-go-related gene potassium channel 2) (Ether-a-go-go-related protein 2) (Eag-related protein 2).

KCNH7_HUMAN
NC score	0.158648 (rank : 32)	θ value	0.279714 (rank : 37)
Query Neighborhood Hits	118	Target Neighborhood Hits	107	Shared Neighborhood Hits	46
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

KCNH7_MOUSE
NC score	0.156996 (rank : 33)	θ value	0.279714 (rank : 38)
Query Neighborhood Hits	118	Target Neighborhood Hits	98	Shared Neighborhood Hits	46
SwissProt Accessions	Q9ER47	Gene names	Kcnh7, Erg3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (Ether-a-go-go-related protein 3) (Eag-related protein 3).

KCNH3_MOUSE
NC score	0.154005 (rank : 34)	θ value	1.06291 (rank : 56)
Query Neighborhood Hits	118	Target Neighborhood Hits	133	Shared Neighborhood Hits	36
SwissProt Accessions	Q9WVJ0	Gene names	Kcnh3, Elk2
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (mElk2).

KCNH2_HUMAN
NC score	0.152788 (rank : 35)	θ value	0.47712 (rank : 42)
Query Neighborhood Hits	118	Target Neighborhood Hits	158	Shared Neighborhood Hits	50
SwissProt Accessions	Q12809, O75418, O75680, Q9BT72, Q9BUT7, Q9H3P0	Gene names	KCNH2, ERG, ERG1, HERG, HERG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (H-ERG) (Erg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (eag homolog).

KCNH2_MOUSE
NC score	0.152683 (rank : 36)	θ value	0.47712 (rank : 43)
Query Neighborhood Hits	118	Target Neighborhood Hits	165	Shared Neighborhood Hits	49
SwissProt Accessions	O35219, O35220, O35221, O35989	Gene names	Kcnh2, Erg, Merg1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 2 (Voltage-gated potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium channel 1) (ERG1) (MERG) (Merg1) (Ether-a-go-go-related protein 1) (Eag-related protein 1).

KCNH3_HUMAN
NC score	0.152361 (rank : 37)	θ value	1.06291 (rank : 55)
Query Neighborhood Hits	118	Target Neighborhood Hits	148	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ULD8, Q9UQ06	Gene names	KCNH3, KIAA1282
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 3 (Voltage-gated potassium channel subunit Kv12.2) (Ether-a-go-go-like potassium channel 2) (ELK channel 2) (ELK2) (Brain-specific eag-like channel 1) (BEC1).

KCNH4_HUMAN
NC score	0.148131 (rank : 38)	θ value	0.125558 (rank : 32)
Query Neighborhood Hits	118	Target Neighborhood Hits	177	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UQ05	Gene names	KCNH4
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 4 (Voltage-gated potassium channel subunit Kv12.3) (Ether-a-go-go-like potassium channel 1) (ELK channel 1) (ELK1) (Brain-specific eag-like channel 2) (BEC2).

KCNQ4_HUMAN
NC score	0.147490 (rank : 39)	θ value	0.125558 (rank : 34)
Query Neighborhood Hits	118	Target Neighborhood Hits	136	Shared Neighborhood Hits	54
SwissProt Accessions	P56696, O96025	Gene names	KCNQ4
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 4 (Voltage-gated potassium channel subunit Kv7.4) (Potassium channel subunit alpha KvLQT4) (KQT-like 4).

KCND1_HUMAN
NC score	0.128531 (rank : 40)	θ value	0.365318 (rank : 41)
Query Neighborhood Hits	118	Target Neighborhood Hits	160	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NSA2, O75671	Gene names	KCND1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1).

KCND2_MOUSE
NC score	0.127314 (rank : 41)	θ value	0.62314 (rank : 45)
Query Neighborhood Hits	118	Target Neighborhood Hits	156	Shared Neighborhood Hits	65
SwissProt Accessions	Q9Z0V2, Q8BSK3, Q8CHB7, Q9JJ60	Gene names	Kcnd2, Kiaa1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCND2_HUMAN
NC score	0.127291 (rank : 42)	θ value	0.62314 (rank : 44)
Query Neighborhood Hits	118	Target Neighborhood Hits	154	Shared Neighborhood Hits	65
SwissProt Accessions	Q9NZV8, O95012, O95021, Q9UBY7, Q9UN98, Q9UNH9	Gene names	KCND2, KIAA1044
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 2 (Voltage-gated potassium channel subunit Kv4.2).

KCNQ5_HUMAN
NC score	0.127181 (rank : 43)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	118	Target Neighborhood Hits	163	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NR82, Q9NRN0, Q9NYA6	Gene names	KCNQ5
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 5 (Voltage-gated potassium channel subunit Kv7.5) (Potassium channel subunit alpha KvLQT5) (KQT-like 5).

KCND3_MOUSE
NC score	0.126484 (rank : 44)	θ value	0.62314 (rank : 47)
Query Neighborhood Hits	118	Target Neighborhood Hits	162	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Z0V1, Q8CC44, Q9Z0V0	Gene names	Kcnd3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND3_HUMAN
NC score	0.126436 (rank : 45)	θ value	0.62314 (rank : 46)
Query Neighborhood Hits	118	Target Neighborhood Hits	162	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UK17, O60576, O60577, Q5T0M0, Q9UH85, Q9UH86, Q9UK16	Gene names	KCND3
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 3 (Voltage-gated potassium channel subunit Kv4.3).

KCND1_MOUSE
NC score	0.124644 (rank : 46)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	118	Target Neighborhood Hits	165	Shared Neighborhood Hits	68
SwissProt Accessions	Q03719, Q8CC68	Gene names	Kcnd1
Domain Architecture
Description	Potassium voltage-gated channel subfamily D member 1 (Voltage-gated potassium channel subunit Kv4.1) (mShal).

KCNQ2_HUMAN
NC score	0.123754 (rank : 47)	θ value	0.62314 (rank : 49)
Query Neighborhood Hits	118	Target Neighborhood Hits	114	Shared Neighborhood Hits	57
SwissProt Accessions	O43526, O43796, O75580, O95845, Q5VYT8, Q96J59, Q99454	Gene names	KCNQ2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Neuroblastoma-specific potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ2_MOUSE
NC score	0.123263 (rank : 48)	θ value	0.62314 (rank : 50)
Query Neighborhood Hits	118	Target Neighborhood Hits	163	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

KCNQ1_HUMAN
NC score	0.119950 (rank : 49)	θ value	0.279714 (rank : 39)
Query Neighborhood Hits	118	Target Neighborhood Hits	99	Shared Neighborhood Hits	49
SwissProt Accessions	P51787, O00347, O60607, O94787, Q7Z6G9, Q92960, Q9UMN8, Q9UMN9	Gene names	KCNQ1, KCNA8, KCNA9, KVLQT1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ1_MOUSE
NC score	0.118875 (rank : 50)	θ value	0.279714 (rank : 40)
Query Neighborhood Hits	118	Target Neighborhood Hits	175	Shared Neighborhood Hits	50
SwissProt Accessions	P97414, O88702, Q7TNZ1, Q7TPL7, Q80VR7	Gene names	Kcnq1, Kcna9, Kvlqt1
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 1 (Voltage-gated potassium channel subunit Kv7.1) (IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1) (KQT-like 1).

KCNQ3_HUMAN
NC score	0.117603 (rank : 51)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	118	Target Neighborhood Hits	114	Shared Neighborhood Hits	53
SwissProt Accessions	O43525	Gene names	KCNQ3
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNQ3_MOUSE
NC score	0.117001 (rank : 52)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	118	Target Neighborhood Hits	105	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K3F6	Gene names	Kcnq3
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily KQT member 3 (Voltage-gated potassium channel subunit Kv7.3) (Potassium channel subunit alpha KvLQT3) (KQT-like 3).

KCNN4_MOUSE
NC score	0.116199 (rank : 53)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	118	Target Neighborhood Hits	85	Shared Neighborhood Hits	55
SwissProt Accessions	O89109, Q3U1J8, Q9CY39	Gene names	Kcnn4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1).

KCNN4_HUMAN
NC score	0.115370 (rank : 54)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	118	Target Neighborhood Hits	90	Shared Neighborhood Hits	55
SwissProt Accessions	O15554	Gene names	KCNN4, IK1, IKCA1, KCA4, SK4
Domain Architecture
Description	Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (KCa4) (IK1) (IKCa1) (Putative Gardos channel).

KCNA4_HUMAN
NC score	0.104106 (rank : 55)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	118	Target Neighborhood Hits	108	Shared Neighborhood Hits	56
SwissProt Accessions	P22459	Gene names	KCNA4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4) (HK1) (HPCN2) (HBK4) (HUKII).

KCNA6_HUMAN
NC score	0.099309 (rank : 56)	θ value	1.06291 (rank : 54)
Query Neighborhood Hits	118	Target Neighborhood Hits	100	Shared Neighborhood Hits	53
SwissProt Accessions	P17658	Gene names	KCNA6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (HBK2).

KCNA5_HUMAN
NC score	0.097901 (rank : 57)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	118	Target Neighborhood Hits	124	Shared Neighborhood Hits	55
SwissProt Accessions	P22460	Gene names	KCNA5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (HK2) (HPCN1).

KCNF1_HUMAN
NC score	0.096716 (rank : 58)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	118	Target Neighborhood Hits	109	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H3M0, O43527	Gene names	KCNF1
Domain Architecture
Description	Potassium voltage-gated channel subfamily F member 1 (Voltage-gated potassium channel subunit Kv5.1) (kH1).

KCNA6_MOUSE
NC score	0.096493 (rank : 59)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	118	Target Neighborhood Hits	106	Shared Neighborhood Hits	51
SwissProt Accessions	Q61923	Gene names	Kcna6
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel subunit Kv1.6) (MK1.6).

KCNA5_MOUSE
NC score	0.095174 (rank : 60)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	118	Target Neighborhood Hits	119	Shared Neighborhood Hits	51
SwissProt Accessions	Q61762	Gene names	Kcna5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 5 (Voltage-gated potassium channel subunit Kv1.5) (KV1-5).

KCNV2_HUMAN
NC score	0.094852 (rank : 61)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	118	Target Neighborhood Hits	137	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDN2	Gene names	KCNV2
Domain Architecture
Description	Potassium voltage-gated channel subfamily V member 2 (Voltage-gated potassium channel subunit Kv8.2).

KCNA4_MOUSE
NC score	0.093386 (rank : 62)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	118	Target Neighborhood Hits	98	Shared Neighborhood Hits	50
SwissProt Accessions	Q61423	Gene names	Kcna4
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 4 (Voltage-gated potassium channel subunit Kv1.4).

KCNA3_MOUSE
NC score	0.093305 (rank : 63)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	118	Target Neighborhood Hits	103	Shared Neighborhood Hits	53
SwissProt Accessions	P16390	Gene names	Kcna3
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (MK3).

KCNA3_HUMAN
NC score	0.091411 (rank : 64)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	118	Target Neighborhood Hits	101	Shared Neighborhood Hits	50
SwissProt Accessions	P22001	Gene names	KCNA3, HGK5
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 3 (Voltage-gated potassium channel subunit Kv1.3) (HPCN3) (HGK5) (HuKIII) (HLK3).

KCNA2_HUMAN
NC score	0.090049 (rank : 65)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	118	Target Neighborhood Hits	101	Shared Neighborhood Hits	54
SwissProt Accessions	P16389	Gene names	KCNA2
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (HBK5) (NGK1) (HUKIV).

KCNA2_MOUSE
NC score	0.089981 (rank : 66)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	118	Target Neighborhood Hits	102	Shared Neighborhood Hits	54
SwissProt Accessions	P63141, P15386, Q02010, Q8C8W4	Gene names	Kcna2
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily A member 2 (Voltage-gated potassium channel subunit Kv1.2) (MK2).

KCNS2_HUMAN
NC score	0.088106 (rank : 67)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	118	Target Neighborhood Hits	129	Shared Neighborhood Hits	52
SwissProt Accessions	Q9ULS6	Gene names	KCNS2, KIAA1144
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNS2_MOUSE
NC score	0.088044 (rank : 68)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	118	Target Neighborhood Hits	130	Shared Neighborhood Hits	52
SwissProt Accessions	O35174, Q543P3	Gene names	Kcns2
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 2 (Voltage-gated potassium channel subunit Kv9.2) (Delayed-rectifier K(+) channel alpha subunit 2).

KCNB2_HUMAN
NC score	0.087966 (rank : 69)	θ value	0.813845 (rank : 51)
Query Neighborhood Hits	118	Target Neighborhood Hits	212	Shared Neighborhood Hits	55
SwissProt Accessions	Q92953, Q9BXD3	Gene names	KCNB2
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 2 (Voltage-gated potassium channel subunit Kv2.2).

KCNC4_MOUSE
NC score	0.086816 (rank : 70)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	118	Target Neighborhood Hits	130	Shared Neighborhood Hits	46
SwissProt Accessions	Q8R1C0	Gene names	Kcnc4
Domain Architecture	No domain graphic available
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4).

KCNC4_HUMAN
NC score	0.086669 (rank : 71)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	118	Target Neighborhood Hits	141	Shared Neighborhood Hits	46
SwissProt Accessions	Q03721, Q3MIM4, Q5TBI6	Gene names	KCNC4
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 4 (Voltage-gated potassium channel subunit Kv3.4) (KSHIIIC).

KCNC3_HUMAN
NC score	0.086639 (rank : 72)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	118	Target Neighborhood Hits	256	Shared Neighborhood Hits	56
SwissProt Accessions	Q14003	Gene names	KCNC3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNB1_HUMAN
NC score	0.086176 (rank : 73)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	118	Target Neighborhood Hits	169	Shared Neighborhood Hits	54
SwissProt Accessions	Q14721, Q14193	Gene names	KCNB1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (h-DRK1).

KCNC1_MOUSE
NC score	0.086134 (rank : 74)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	118	Target Neighborhood Hits	133	Shared Neighborhood Hits	47
SwissProt Accessions	P15388	Gene names	Kcnc1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNB1_MOUSE
NC score	0.086100 (rank : 75)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	118	Target Neighborhood Hits	154	Shared Neighborhood Hits	53
SwissProt Accessions	Q03717	Gene names	Kcnb1
Domain Architecture
Description	Potassium voltage-gated channel subfamily B member 1 (Voltage-gated potassium channel subunit Kv2.1) (mShab).

KCNC1_HUMAN
NC score	0.086081 (rank : 76)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	118	Target Neighborhood Hits	133	Shared Neighborhood Hits	47
SwissProt Accessions	P48547	Gene names	KCNC1
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 1 (Voltage-gated potassium channel subunit Kv3.1) (Kv4) (NGK2).

KCNN1_MOUSE
NC score	0.084871 (rank : 77)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	118	Target Neighborhood Hits	117	Shared Neighborhood Hits	51
SwissProt Accessions	Q9EQR3, Q99JA9	Gene names	Kcnn1, Sk1
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

KCNA1_MOUSE
NC score	0.084667 (rank : 78)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	118	Target Neighborhood Hits	103	Shared Neighborhood Hits	49
SwissProt Accessions	P16388	Gene names	Kcna1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (MKI) (MBK1).

KCNA1_HUMAN
NC score	0.084624 (rank : 79)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	118	Target Neighborhood Hits	104	Shared Neighborhood Hits	49
SwissProt Accessions	Q09470	Gene names	KCNA1
Domain Architecture
Description	Potassium voltage-gated channel subfamily A member 1 (Voltage-gated potassium channel subunit Kv1.1) (HUKI) (HBK1).

KCNS1_MOUSE
NC score	0.084294 (rank : 80)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	118	Target Neighborhood Hits	114	Shared Neighborhood Hits	52
SwissProt Accessions	O35173	Gene names	Kcns1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNG2_HUMAN
NC score	0.083384 (rank : 81)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	118	Target Neighborhood Hits	83	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UJ96	Gene names	KCNG2, KCNF2
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 2 (Voltage-gated potassium channel subunit Kv6.2) (Cardiac potassium channel subunit).

KCNN1_HUMAN
NC score	0.082353 (rank : 82)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	118	Target Neighborhood Hits	125	Shared Neighborhood Hits	49
SwissProt Accessions	Q92952	Gene names	KCNN1, SK
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 1 (SK1).

KCNG1_HUMAN
NC score	0.082038 (rank : 83)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	118	Target Neighborhood Hits	103	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UIX4, O43528, Q9BRC1	Gene names	KCNG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 1 (Voltage-gated potassium channel subunit Kv6.1) (kH2).

KCNC3_MOUSE
NC score	0.079120 (rank : 84)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	118	Target Neighborhood Hits	173	Shared Neighborhood Hits	49
SwissProt Accessions	Q63959, Q62088	Gene names	Kcnc3
Domain Architecture
Description	Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3) (KSHIIID).

KCNN3_HUMAN
NC score	0.077435 (rank : 85)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	118	Target Neighborhood Hits	216	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UGI6, O43517	Gene names	KCNN3, K3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3) (SKCa3).

KCNN3_MOUSE
NC score	0.076817 (rank : 86)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	118	Target Neighborhood Hits	171	Shared Neighborhood Hits	49
SwissProt Accessions	P58391	Gene names	Kcnn3, Sk3
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 3 (SK3).

KCNN2_MOUSE
NC score	0.076473 (rank : 87)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	118	Target Neighborhood Hits	120	Shared Neighborhood Hits	50
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_HUMAN
NC score	0.076468 (rank : 88)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	118	Target Neighborhood Hits	117	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNS1_HUMAN
NC score	0.074211 (rank : 89)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	118	Target Neighborhood Hits	116	Shared Neighborhood Hits	43
SwissProt Accessions	Q96KK3, O43652, Q6DJU6	Gene names	KCNS1
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 1 (Voltage-gated potassium channel subunit Kv9.1) (Delayed-rectifier K(+) channel alpha subunit 1).

KCNG4_HUMAN
NC score	0.071720 (rank : 90)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	118	Target Neighborhood Hits	99	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TDN1, Q96H24	Gene names	KCNG4, KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4).

KCNS3_HUMAN
NC score	0.067178 (rank : 91)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	118	Target Neighborhood Hits	125	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BQ31, O43651, Q96B56	Gene names	KCNS3
Domain Architecture
Description	Potassium voltage-gated channel subfamily S member 3 (Voltage-gated potassium channel subunit Kv9.3) (Delayed-rectifier K(+) channel alpha subunit 3).

KCNG3_MOUSE
NC score	0.064410 (rank : 92)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	118	Target Neighborhood Hits	91	Shared Neighborhood Hits	40
SwissProt Accessions	P59053	Gene names	Kcng3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

KCNG3_HUMAN
NC score	0.064371 (rank : 93)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	118	Target Neighborhood Hits	91	Shared Neighborhood Hits	39
SwissProt Accessions	Q8TAE7	Gene names	KCNG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily G member 3 (Voltage-gated potassium channel subunit Kv6.3) (Kv10.1).

CNGA2_MOUSE
NC score	0.051720 (rank : 94)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	118	Target Neighborhood Hits	86	Shared Neighborhood Hits	18
SwissProt Accessions	Q62398	Gene names	Cnga2, Cncg2, Cncg4
Domain Architecture
Description	Cyclic nucleotide-gated olfactory channel (Cyclic nucleotide-gated cation channel 2) (CNG channel 2) (CNG-2) (CNG2).

CNGA3_MOUSE
NC score	0.050891 (rank : 95)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	118	Target Neighborhood Hits	84	Shared Neighborhood Hits	19
SwissProt Accessions	Q9JJZ8, Q9WV01	Gene names	Cnga3, Cng3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel alpha 3 (CNG channel alpha 3) (CNG-3) (CNG3) (Cyclic nucleotide-gated channel alpha 3) (Cone photoreceptor cGMP-gated channel subunit alpha).

HCN2_HUMAN
NC score	0.050601 (rank : 96)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	118	Target Neighborhood Hits	369	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UL51, O60742, O60743, O75267, Q9UBS2	Gene names	HCN2, BCNG2
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2).

HCN2_MOUSE
NC score	0.050211 (rank : 97)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	118	Target Neighborhood Hits	278	Shared Neighborhood Hits	32
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

NRAM1_HUMAN
NC score	0.049365 (rank : 98)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	118	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	P49279	Gene names	SLC11A1, NRAMP, NRAMP1
Domain Architecture
Description	Natural resistance-associated macrophage protein 1 (NRAMP 1).

NRAM1_MOUSE
NC score	0.048644 (rank : 99)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	118	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	P41251	Gene names	Slc11a1, Bcg, Ity, Lsh, Nramp1
Domain Architecture
Description	Natural resistance-associated macrophage protein 1 (NRAMP 1).

NRAM2_HUMAN
NC score	0.041618 (rank : 100)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	118	Target Neighborhood Hits	11	Shared Neighborhood Hits	6
SwissProt Accessions	P49281, O43288, O60932, Q96J35	Gene names	SLC11A2, NRAMP2
Domain Architecture
Description	Natural resistance-associated macrophage protein 2 (NRAMP 2) (Divalent metal transporter 1) (DMT1).

NRAM2_MOUSE
NC score	0.040325 (rank : 101)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	118	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	P49282, O54903	Gene names	Slc11a2, Nramp2
Domain Architecture
Description	Natural resistance-associated macrophage protein 2 (NRAMP 2).

MYRIP_HUMAN
NC score	0.037095 (rank : 102)	θ value	0.0563607 (rank : 27)
Query Neighborhood Hits	118	Target Neighborhood Hits	269	Shared Neighborhood Hits	10
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

OGFR_HUMAN
NC score	0.034196 (rank : 103)	θ value	0.0431538 (rank : 26)
Query Neighborhood Hits	118	Target Neighborhood Hits	1582	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

YIF1A_HUMAN
NC score	0.031712 (rank : 104)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	118	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	O95070, Q96G83, Q9BVD0	Gene names	YIF1A, 54TM, HYIF1P, YIF1
Domain Architecture	No domain graphic available
Description	Protein YIF1A (YIP1-interacting factor homolog A) (54TMp).

IF4B_HUMAN
NC score	0.029160 (rank : 105)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	118	Target Neighborhood Hits	417	Shared Neighborhood Hits	9
SwissProt Accessions	P23588	Gene names	EIF4B
Domain Architecture
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

CJ078_MOUSE
NC score	0.027446 (rank : 106)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	118	Target Neighborhood Hits	559	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

IF4B_MOUSE
NC score	0.025005 (rank : 107)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	118	Target Neighborhood Hits	368	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

CS007_MOUSE
NC score	0.023724 (rank : 108)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	118	Target Neighborhood Hits	464	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

SNPC4_HUMAN
NC score	0.022935 (rank : 109)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	118	Target Neighborhood Hits	589	Shared Neighborhood Hits	18
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

YIF1A_MOUSE
NC score	0.020462 (rank : 110)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	118	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	Q91XB7, Q9CWB2	Gene names	Yif1a
Domain Architecture	No domain graphic available
Description	Protein YIF1A (YIP1-interacting factor homolog A).

TOPB1_MOUSE
NC score	0.020357 (rank : 111)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	118	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q6ZQF0, Q6P6P0, Q80Y33, Q8BUI0, Q8BUK1, Q8R348, Q91VX3, Q922X8	Gene names	Topbp1, Kiaa0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase II-binding protein 1 (DNA topoisomerase IIbeta- binding protein 1) (TopBP1).

CK024_HUMAN
NC score	0.019715 (rank : 112)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	118	Target Neighborhood Hits	408	Shared Neighborhood Hits	16
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

PRRT3_HUMAN
NC score	0.018952 (rank : 113)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	118	Target Neighborhood Hits	998	Shared Neighborhood Hits	24
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

CAC1H_MOUSE
NC score	0.017882 (rank : 114)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	118	Target Neighborhood Hits	230	Shared Neighborhood Hits	28
SwissProt Accessions	O88427, Q80TJ2, Q9JKU5	Gene names	Cacna1h, Kiaa1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1H (Voltage- gated calcium channel subunit alpha Cav3.2).

MUC1_HUMAN
NC score	0.017677 (rank : 115)	θ value	0.0961366 (rank : 31)
Query Neighborhood Hits	118	Target Neighborhood Hits	975	Shared Neighborhood Hits	24
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

BAP1_MOUSE
NC score	0.017491 (rank : 116)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	118	Target Neighborhood Hits	118	Shared Neighborhood Hits	8
SwissProt Accessions	Q99PU7, Q6ZQE6	Gene names	Bap1, Kiaa0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Ubiquitin C-terminal hydrolase X4) (UCH-X4).

BAP1_HUMAN
NC score	0.017466 (rank : 117)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	118	Target Neighborhood Hits	106	Shared Neighborhood Hits	7
SwissProt Accessions	Q92560, Q6LEM0, Q7Z5E8	Gene names	BAP1, KIAA0272
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1- associated protein 1) (Cerebral protein 6).

CIKS_HUMAN
NC score	0.017230 (rank : 118)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	118	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	O43734, Q5R3A3, Q9H5W2, Q9H6Y3, Q9NS14, Q9UG72	Gene names	TRAF3IP2, C6orf4, C6orf5
Domain Architecture	No domain graphic available
Description	Adapter protein CIKS (Connection to IKK and SAPK/JNK) (TRAF3- interacting protein 2) (Nuclear factor NF-kappa-B activator 1) (ACT1).

PCLO_MOUSE
NC score	0.016059 (rank : 119)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	118	Target Neighborhood Hits	2275	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SON_MOUSE
NC score	0.015916 (rank : 120)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	118	Target Neighborhood Hits	957	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

BAZ2A_HUMAN
NC score	0.014617 (rank : 121)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	118	Target Neighborhood Hits	780	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CASC3_MOUSE
NC score	0.012153 (rank : 122)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	118	Target Neighborhood Hits	333	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K3W3, Q8K219, Q99NF0	Gene names	Casc3, Mln51
Domain Architecture	No domain graphic available
Description	Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node protein 51 homolog) (Protein MLN 51 homolog) (Protein barentsz) (Btz).

PPIP2_HUMAN
NC score	0.012109 (rank : 123)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	118	Target Neighborhood Hits	254	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H939	Gene names	PSTPIP2
Domain Architecture
Description	Proline-serine-threonine phosphatase-interacting protein 2.

INP5E_HUMAN
NC score	0.011278 (rank : 124)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	118	Target Neighborhood Hits	201	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NRR6, Q15734	Gene names	INPP5E
Domain Architecture
Description	72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol-4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV).

ASPP1_MOUSE
NC score	0.010415 (rank : 125)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	118	Target Neighborhood Hits	1244	Shared Neighborhood Hits	22
SwissProt Accessions	Q62415	Gene names	Ppp1r13b, Aspp1
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

MAP1A_HUMAN
NC score	0.009959 (rank : 126)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	118	Target Neighborhood Hits	1626	Shared Neighborhood Hits	25
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

HSF1_MOUSE
NC score	0.009728 (rank : 127)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	118	Target Neighborhood Hits	267	Shared Neighborhood Hits	9
SwissProt Accessions	P38532, O70462	Gene names	Hsf1
Domain Architecture
Description	Heat shock factor protein 1 (HSF 1) (Heat shock transcription factor 1) (HSTF 1).

APBA2_HUMAN
NC score	0.009590 (rank : 128)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	118	Target Neighborhood Hits	220	Shared Neighborhood Hits	6
SwissProt Accessions	Q99767, O60571	Gene names	APBA2, MINT2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

CSPG5_MOUSE
NC score	0.009022 (rank : 129)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	118	Target Neighborhood Hits	211	Shared Neighborhood Hits	6
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

WNK2_HUMAN
NC score	0.008440 (rank : 130)	θ value	0.0736092 (rank : 28)
Query Neighborhood Hits	118	Target Neighborhood Hits	1407	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ANR11_HUMAN
NC score	0.008395 (rank : 131)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	118	Target Neighborhood Hits	1289	Shared Neighborhood Hits	20
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

K1849_MOUSE
NC score	0.007746 (rank : 132)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	118	Target Neighborhood Hits	335	Shared Neighborhood Hits	8
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

MAGE1_HUMAN
NC score	0.007718 (rank : 133)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	118	Target Neighborhood Hits	1389	Shared Neighborhood Hits	34
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

SEPT9_HUMAN
NC score	0.006987 (rank : 134)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	118	Target Neighborhood Hits	706	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

NFH_MOUSE
NC score	0.006952 (rank : 135)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	118	Target Neighborhood Hits	2247	Shared Neighborhood Hits	32
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SRC8_MOUSE
NC score	0.006784 (rank : 136)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	118	Target Neighborhood Hits	292	Shared Neighborhood Hits	3
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

L2GL1_HUMAN
NC score	0.006566 (rank : 137)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	118	Target Neighborhood Hits	64	Shared Neighborhood Hits	5
SwissProt Accessions	Q15334, O00188, Q58F11, Q86UK6	Gene names	LLGL1, HUGL
Domain Architecture	No domain graphic available
Description	Lethal(2) giant larvae protein homolog 1 (LLGL) (Human homolog to the D-lgl gene) (Hugl-1) (DLG4).

UBP31_HUMAN
NC score	0.006057 (rank : 138)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	118	Target Neighborhood Hits	293	Shared Neighborhood Hits	11
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

MEGF9_MOUSE
NC score	0.005967 (rank : 139)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	118	Target Neighborhood Hits	896	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

AQP8_HUMAN
NC score	0.005630 (rank : 140)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	118	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	O94778, Q8IUU3, Q9UIA4	Gene names	AQP8
Domain Architecture
Description	Aquaporin-8 (AQP-8).

PO6F1_MOUSE
NC score	0.002796 (rank : 141)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	118	Target Neighborhood Hits	581	Shared Neighborhood Hits	10
SwissProt Accessions	Q07916, Q91XK3	Gene names	Pou6f1, Emb
Domain Architecture
Description	POU domain, class 6, transcription factor 1 (Octamer-binding transcription factor EMB) (Transcription regulatory protein MCP-1).

HIRA_MOUSE
NC score	0.002670 (rank : 142)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	118	Target Neighborhood Hits	274	Shared Neighborhood Hits	4
SwissProt Accessions	Q61666, O08845, Q62365	Gene names	Hira, Tuple1
Domain Architecture
Description	HIRA protein (TUP1-like enhancer of split protein 1).

MAST4_HUMAN
NC score	0.000752 (rank : 143)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	118	Target Neighborhood Hits	1804	Shared Neighborhood Hits	40
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

SPEG_MOUSE
NC score	-0.000241 (rank : 144)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	118	Target Neighborhood Hits	1959	Shared Neighborhood Hits	33
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

GLIS3_MOUSE
NC score	-0.000430 (rank : 145)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	118	Target Neighborhood Hits	861	Shared Neighborhood Hits	10
SwissProt Accessions	Q6XP49, Q8BI60	Gene names	Glis3
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3).

EPHAA_HUMAN
NC score	-0.000619 (rank : 146)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	118	Target Neighborhood Hits	960	Shared Neighborhood Hits	8
SwissProt Accessions	Q5JZY3, Q6NW42	Gene names	EPHA10
Domain Architecture	No domain graphic available
Description	Ephrin type-A receptor 10 precursor (EC 2.7.10.1).

STK6_MOUSE
NC score	-0.002312 (rank : 147)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	118	Target Neighborhood Hits	886	Shared Neighborhood Hits	6
SwissProt Accessions	P97477, O35624, Q91YU4	Gene names	Stk6, Ark1, Aurka, Ayk1, Iak1
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1).