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Network neighborhood for query Sequence : SATB1_MOUSE

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SATB1_MOUSE
SwissProt Accessions	Q60611	Gene names	Satb1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SATB1_HUMAN
θ value	0 (rank : 1)	NC score	0.992823 (rank : 2)
Query Neighborhood Hits	130	Target Neighborhood Hits	130	Shared Neighborhood Hits	104
SwissProt Accessions	Q01826	Gene names	SATB1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

SATB1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	130	Target Neighborhood Hits	130	Shared Neighborhood Hits	130
SwissProt Accessions	Q60611	Gene names	Satb1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

SATB2_HUMAN
θ value	0 (rank : 3)	NC score	0.970475 (rank : 3)
Query Neighborhood Hits	130	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UPW6	Gene names	SATB2, KIAA1034
Domain Architecture
Description	DNA-binding protein SATB2 (Special AT-rich sequence-binding protein 2).

SATB2_MOUSE
θ value	0 (rank : 4)	NC score	0.970383 (rank : 4)
Query Neighborhood Hits	130	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VI24	Gene names	Satb2, Kiaa1034
Domain Architecture
Description	DNA-binding protein SATB2 (Special AT-rich sequence-binding protein 2).

ONEC2_HUMAN
θ value	7.1131e-05 (rank : 5)	NC score	0.279328 (rank : 5)
Query Neighborhood Hits	130	Target Neighborhood Hits	115	Shared Neighborhood Hits	31
SwissProt Accessions	O95948	Gene names	ONECUT2
Domain Architecture
Description	One cut domain family member 2 (Transcription factor ONECUT-2) (OC-2).

ONEC2_MOUSE
θ value	7.1131e-05 (rank : 6)	NC score	0.277212 (rank : 6)
Query Neighborhood Hits	130	Target Neighborhood Hits	123	Shared Neighborhood Hits	29
SwissProt Accessions	Q6XBJ3	Gene names	Onecut2, Oc2
Domain Architecture	No domain graphic available
Description	One cut domain family member 2 (Transcription factor ONECUT-2) (OC-2).

HNF6_HUMAN
θ value	0.00020696 (rank : 7)	NC score	0.270438 (rank : 8)
Query Neighborhood Hits	130	Target Neighborhood Hits	127	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBC0, Q99744, Q9UMR6	Gene names	ONECUT1, HNF6, HNF6A
Domain Architecture
Description	Hepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1).

HNF6_MOUSE
θ value	0.00020696 (rank : 8)	NC score	0.270711 (rank : 7)
Query Neighborhood Hits	130	Target Neighborhood Hits	124	Shared Neighborhood Hits	29
SwissProt Accessions	O08755	Gene names	Onecut1, Hnf6, Hnf6a
Domain Architecture
Description	Hepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1).

BPTF_HUMAN
θ value	0.000461057 (rank : 9)	NC score	0.076291 (rank : 31)
Query Neighborhood Hits	130	Target Neighborhood Hits	786	Shared Neighborhood Hits	25
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

ATBF1_MOUSE
θ value	0.00665767 (rank : 10)	NC score	0.111592 (rank : 13)
Query Neighborhood Hits	130	Target Neighborhood Hits	1841	Shared Neighborhood Hits	84
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

PO2F1_HUMAN
θ value	0.00869519 (rank : 11)	NC score	0.068593 (rank : 48)
Query Neighborhood Hits	130	Target Neighborhood Hits	426	Shared Neighborhood Hits	56
SwissProt Accessions	P14859, Q5TBT7, Q6PK46, Q8NEU9, Q9BPV1	Gene names	POU2F1, OCT1, OTF1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

ATBF1_HUMAN
θ value	0.0148317 (rank : 12)	NC score	0.112864 (rank : 12)
Query Neighborhood Hits	130	Target Neighborhood Hits	1547	Shared Neighborhood Hits	77
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CUTL1_HUMAN
θ value	0.0193708 (rank : 13)	NC score	0.079255 (rank : 27)
Query Neighborhood Hits	130	Target Neighborhood Hits	1574	Shared Neighborhood Hits	70
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

TNR6A_HUMAN
θ value	0.0330416 (rank : 14)	NC score	0.078474 (rank : 28)
Query Neighborhood Hits	130	Target Neighborhood Hits	343	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

ZFHX2_HUMAN
θ value	0.0330416 (rank : 15)	NC score	0.109798 (rank : 15)
Query Neighborhood Hits	130	Target Neighborhood Hits	1178	Shared Neighborhood Hits	69
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

HOMEZ_HUMAN
θ value	0.0736092 (rank : 16)	NC score	0.130329 (rank : 10)
Query Neighborhood Hits	130	Target Neighborhood Hits	110	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IX15, Q6P049, Q86XB6, Q9P2A5	Gene names	HOMEZ, KIAA1443
Domain Architecture
Description	Homeobox and leucine zipper protein Homez (Homeodomain leucine zipper- containing factor).

HOMEZ_MOUSE
θ value	0.0736092 (rank : 17)	NC score	0.154395 (rank : 9)
Query Neighborhood Hits	130	Target Neighborhood Hits	61	Shared Neighborhood Hits	12
SwissProt Accessions	Q80W88	Gene names	Homez, Kiaa1443
Domain Architecture
Description	Homeobox and leucine zipper protein Homez (Homeodomain leucine zipper- containing factor).

DVL2_MOUSE
θ value	0.163984 (rank : 18)	NC score	0.036386 (rank : 119)
Query Neighborhood Hits	130	Target Neighborhood Hits	233	Shared Neighborhood Hits	7
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

LHX61_HUMAN
θ value	0.163984 (rank : 19)	NC score	0.089044 (rank : 21)
Query Neighborhood Hits	130	Target Neighborhood Hits	412	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UPM6, Q5T7S8, Q9NTK3, Q9UPM5	Gene names	LHX6, LHX6.1
Domain Architecture
Description	LIM/homeobox protein Lhx6.1 (Lhx6).

LHX6_MOUSE
θ value	0.163984 (rank : 20)	NC score	0.091689 (rank : 19)
Query Neighborhood Hits	130	Target Neighborhood Hits	399	Shared Neighborhood Hits	50
SwissProt Accessions	O88706	Gene names	Lhx6
Domain Architecture
Description	LIM/homeobox protein Lhx6.

PEPP1_HUMAN
θ value	0.163984 (rank : 21)	NC score	0.072322 (rank : 38)
Query Neighborhood Hits	130	Target Neighborhood Hits	338	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NHV9, O95030, Q3SYE0	Gene names	PEPP1, OTEX
Domain Architecture
Description	Paired-like homeobox protein PEPP-1 (Ovary-, testis- and epididymis- expressed gene protein).

CUTL1_MOUSE
θ value	0.21417 (rank : 22)	NC score	0.071352 (rank : 39)
Query Neighborhood Hits	130	Target Neighborhood Hits	1620	Shared Neighborhood Hits	68
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

ESX1L_HUMAN
θ value	0.21417 (rank : 23)	NC score	0.094117 (rank : 17)
Query Neighborhood Hits	130	Target Neighborhood Hits	498	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

PAX6_HUMAN
θ value	0.21417 (rank : 24)	NC score	0.081261 (rank : 25)
Query Neighborhood Hits	130	Target Neighborhood Hits	383	Shared Neighborhood Hits	50
SwissProt Accessions	P26367, Q6N006, Q99413	Gene names	PAX6, AN2
Domain Architecture
Description	Paired box protein Pax-6 (Oculorhombin) (Aniridia type II protein).

PAX6_MOUSE
θ value	0.21417 (rank : 25)	NC score	0.081261 (rank : 26)
Query Neighborhood Hits	130	Target Neighborhood Hits	383	Shared Neighborhood Hits	50
SwissProt Accessions	P63015, P32117, P70601, Q62222, Q64037, Q8CEI5, Q8VDB5, Q921Q8	Gene names	Pax6, Pax-6, Sey
Domain Architecture	No domain graphic available
Description	Paired box protein Pax-6 (Oculorhombin).

VSX1_MOUSE
θ value	0.21417 (rank : 26)	NC score	0.097239 (rank : 16)
Query Neighborhood Hits	130	Target Neighborhood Hits	356	Shared Neighborhood Hits	49
SwissProt Accessions	Q91V10	Gene names	Vsx1, Rinx
Domain Architecture
Description	Visual system homeobox 1 (Transcription factor VSX1) (Retinal inner nuclear layer homeobox protein) (Homeodomain protein RINX).

HESX1_MOUSE
θ value	0.365318 (rank : 27)	NC score	0.076115 (rank : 32)
Query Neighborhood Hits	130	Target Neighborhood Hits	331	Shared Neighborhood Hits	49
SwissProt Accessions	Q61658, Q61047	Gene names	Hesx1, Hes-1, Rpx
Domain Architecture
Description	Homeobox expressed in ES cells 1 (Homeobox protein ANF) (Anterior- restricted homeobox protein) (Rathke pouch homeo box).

HME1_HUMAN
θ value	0.365318 (rank : 28)	NC score	0.072927 (rank : 35)
Query Neighborhood Hits	130	Target Neighborhood Hits	384	Shared Neighborhood Hits	49
SwissProt Accessions	Q05925	Gene names	EN1
Domain Architecture
Description	Homeobox protein engrailed-1 (Hu-En-1).

HME1_MOUSE
θ value	0.365318 (rank : 29)	NC score	0.072754 (rank : 36)
Query Neighborhood Hits	130	Target Neighborhood Hits	397	Shared Neighborhood Hits	48
SwissProt Accessions	P09065	Gene names	En1, En-1
Domain Architecture
Description	Homeobox protein engrailed-1 (Mo-En-1).

MA1B1_HUMAN
θ value	0.365318 (rank : 30)	NC score	0.037711 (rank : 117)
Query Neighborhood Hits	130	Target Neighborhood Hits	125	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

ALX3_HUMAN
θ value	0.47712 (rank : 31)	NC score	0.068711 (rank : 47)
Query Neighborhood Hits	130	Target Neighborhood Hits	380	Shared Neighborhood Hits	46
SwissProt Accessions	O95076, O95075	Gene names	ALX3
Domain Architecture
Description	Homeobox protein aristaless-like 3 (Proline-rich transcription factor ALX3).

AMOL2_HUMAN
θ value	0.47712 (rank : 32)	NC score	0.034280 (rank : 122)
Query Neighborhood Hits	130	Target Neighborhood Hits	603	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

LHX61_MOUSE
θ value	0.47712 (rank : 33)	NC score	0.081906 (rank : 24)
Query Neighborhood Hits	130	Target Neighborhood Hits	396	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R1R0, Q9R1R1	Gene names	Lhx6.1
Domain Architecture
Description	LIM/homeobox protein Lhx6.1.

ALX3_MOUSE
θ value	0.62314 (rank : 34)	NC score	0.067891 (rank : 49)
Query Neighborhood Hits	130	Target Neighborhood Hits	386	Shared Neighborhood Hits	46
SwissProt Accessions	O70137	Gene names	Alx3
Domain Architecture
Description	Homeobox protein aristaless-like 3 (Proline-rich transcription factor ALX3).

ALX4_HUMAN
θ value	0.62314 (rank : 35)	NC score	0.072425 (rank : 37)
Query Neighborhood Hits	130	Target Neighborhood Hits	394	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H161, Q96JN7, Q9H198, Q9HAY9	Gene names	ALX4, KIAA1788
Domain Architecture
Description	Homeobox protein aristaless-like 4.

FOXJ3_MOUSE
θ value	0.62314 (rank : 36)	NC score	0.020259 (rank : 146)
Query Neighborhood Hits	130	Target Neighborhood Hits	190	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BUR3, Q3UTD8	Gene names	Foxj3, Kiaa1041
Domain Architecture
Description	Forkhead box protein J3.

UBQL4_HUMAN
θ value	0.62314 (rank : 37)	NC score	0.039349 (rank : 113)
Query Neighborhood Hits	130	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRR5, Q9BR98, Q9UHX4	Gene names	UBQLN4, C1orf6, UBIN
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

ZHX2_MOUSE
θ value	0.62314 (rank : 38)	NC score	0.083249 (rank : 23)
Query Neighborhood Hits	130	Target Neighborhood Hits	435	Shared Neighborhood Hits	42
SwissProt Accessions	Q8C0C0	Gene names	Zhx2, Afr1, Raf
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

ZHX3_HUMAN
θ value	0.62314 (rank : 39)	NC score	0.077253 (rank : 30)
Query Neighborhood Hits	130	Target Neighborhood Hits	331	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H4I2, O43145	Gene names	ZHX3, KIAA0395, TIX1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

ZHX3_MOUSE
θ value	0.62314 (rank : 40)	NC score	0.078108 (rank : 29)
Query Neighborhood Hits	130	Target Neighborhood Hits	321	Shared Neighborhood Hits	45
SwissProt Accessions	Q8C0Q2, Q80U14	Gene names	Zhx3, Kiaa0395, Tix1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

HME2_HUMAN
θ value	0.813845 (rank : 41)	NC score	0.069364 (rank : 46)
Query Neighborhood Hits	130	Target Neighborhood Hits	355	Shared Neighborhood Hits	49
SwissProt Accessions	P19622	Gene names	EN2
Domain Architecture
Description	Homeobox protein engrailed-2 (Hu-En-2).

HME2_MOUSE
θ value	0.813845 (rank : 42)	NC score	0.069702 (rank : 45)
Query Neighborhood Hits	130	Target Neighborhood Hits	352	Shared Neighborhood Hits	49
SwissProt Accessions	P09066	Gene names	En2, En-2
Domain Architecture
Description	Homeobox protein engrailed-2 (Mo-En-2).

SRC8_MOUSE
θ value	0.813845 (rank : 43)	NC score	0.017999 (rank : 148)
Query Neighborhood Hits	130	Target Neighborhood Hits	292	Shared Neighborhood Hits	9
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

EEA1_HUMAN
θ value	1.06291 (rank : 44)	NC score	0.015509 (rank : 153)
Query Neighborhood Hits	130	Target Neighborhood Hits	1796	Shared Neighborhood Hits	28
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

NPBL_MOUSE
θ value	1.06291 (rank : 45)	NC score	0.031727 (rank : 125)
Query Neighborhood Hits	130	Target Neighborhood Hits	1041	Shared Neighborhood Hits	29
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PCQAP_HUMAN
θ value	1.06291 (rank : 46)	NC score	0.045508 (rank : 110)
Query Neighborhood Hits	130	Target Neighborhood Hits	549	Shared Neighborhood Hits	17
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

RX_HUMAN
θ value	1.06291 (rank : 47)	NC score	0.071251 (rank : 40)
Query Neighborhood Hits	130	Target Neighborhood Hits	423	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

SHOX2_HUMAN
θ value	1.06291 (rank : 48)	NC score	0.093848 (rank : 18)
Query Neighborhood Hits	130	Target Neighborhood Hits	353	Shared Neighborhood Hits	52
SwissProt Accessions	O60902, O60465, O60467, O60903	Gene names	SHOX2, OG12X, SHOT
Domain Architecture
Description	Short stature homeobox protein 2 (Paired-related homeobox protein SHOT) (Homeobox protein Og12X).

SHOX2_MOUSE
θ value	1.06291 (rank : 49)	NC score	0.091639 (rank : 20)
Query Neighborhood Hits	130	Target Neighborhood Hits	348	Shared Neighborhood Hits	52
SwissProt Accessions	P70390, P70369	Gene names	Shox2, Og12x, Prx3
Domain Architecture
Description	Short stature homeobox protein 2 (Homeobox protein Og12X) (OG-12) (Paired family homeodomain protein Prx3).

ARI1A_HUMAN
θ value	1.38821 (rank : 50)	NC score	0.034710 (rank : 121)
Query Neighborhood Hits	130	Target Neighborhood Hits	787	Shared Neighborhood Hits	32
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CUTL2_HUMAN
θ value	1.38821 (rank : 51)	NC score	0.110888 (rank : 14)
Query Neighborhood Hits	130	Target Neighborhood Hits	906	Shared Neighborhood Hits	58
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

HOOK2_MOUSE
θ value	1.38821 (rank : 52)	NC score	0.022123 (rank : 142)
Query Neighborhood Hits	130	Target Neighborhood Hits	736	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

KIF11_HUMAN
θ value	1.38821 (rank : 53)	NC score	0.011939 (rank : 161)
Query Neighborhood Hits	130	Target Neighborhood Hits	583	Shared Neighborhood Hits	11
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

OXRP_HUMAN
θ value	1.38821 (rank : 54)	NC score	0.017701 (rank : 150)
Query Neighborhood Hits	130	Target Neighborhood Hits	544	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PAX4_MOUSE
θ value	1.38821 (rank : 55)	NC score	0.070603 (rank : 41)
Query Neighborhood Hits	130	Target Neighborhood Hits	370	Shared Neighborhood Hits	53
SwissProt Accessions	P32115, P97341, Q9QUR1, Q9R091	Gene names	Pax4, Pax-4
Domain Architecture
Description	Paired box protein Pax-4.

SN1L2_MOUSE
θ value	1.38821 (rank : 56)	NC score	0.001883 (rank : 178)
Query Neighborhood Hits	130	Target Neighborhood Hits	944	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).

UBQL4_MOUSE
θ value	1.38821 (rank : 57)	NC score	0.035475 (rank : 120)
Query Neighborhood Hits	130	Target Neighborhood Hits	99	Shared Neighborhood Hits	8
SwissProt Accessions	Q99NB8, Q8BP88	Gene names	Ubqln4, Ubin
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

ZN142_HUMAN
θ value	1.38821 (rank : 58)	NC score	0.004094 (rank : 175)
Query Neighborhood Hits	130	Target Neighborhood Hits	1007	Shared Neighborhood Hits	24
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

ALX4_MOUSE
θ value	1.81305 (rank : 59)	NC score	0.075230 (rank : 34)
Query Neighborhood Hits	130	Target Neighborhood Hits	369	Shared Neighborhood Hits	48
SwissProt Accessions	O35137	Gene names	Alx4
Domain Architecture
Description	Homeobox protein aristaless-like 4 (ALX-4).

BAG3_MOUSE
θ value	1.81305 (rank : 60)	NC score	0.029123 (rank : 129)
Query Neighborhood Hits	130	Target Neighborhood Hits	513	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CHX10_HUMAN
θ value	1.81305 (rank : 61)	NC score	0.070531 (rank : 43)
Query Neighborhood Hits	130	Target Neighborhood Hits	340	Shared Neighborhood Hits	47
SwissProt Accessions	P58304	Gene names	CHX10, VSX2
Domain Architecture
Description	Homeobox protein CHX10 (Ceh-10 homeodomain-containing homolog).

CHX10_MOUSE
θ value	1.81305 (rank : 62)	NC score	0.070553 (rank : 42)
Query Neighborhood Hits	130	Target Neighborhood Hits	340	Shared Neighborhood Hits	48
SwissProt Accessions	Q61412	Gene names	Chx10, Vsx2
Domain Architecture
Description	Homeobox protein CHX10 (Ceh-10 homeodomain-containing homolog).

EP400_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.026516 (rank : 131)
Query Neighborhood Hits	130	Target Neighborhood Hits	556	Shared Neighborhood Hits	21
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

FYB_HUMAN
θ value	1.81305 (rank : 64)	NC score	0.037411 (rank : 118)
Query Neighborhood Hits	130	Target Neighborhood Hits	379	Shared Neighborhood Hits	16
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

MKL1_MOUSE
θ value	1.81305 (rank : 65)	NC score	0.029523 (rank : 128)
Query Neighborhood Hits	130	Target Neighborhood Hits	667	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

SHOX_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.085818 (rank : 22)
Query Neighborhood Hits	130	Target Neighborhood Hits	363	Shared Neighborhood Hits	54
SwissProt Accessions	O15266, O00412, O00413, O15267	Gene names	SHOX, PHOG
Domain Architecture
Description	Short stature homeobox protein (Short stature homeobox-containing protein) (Pseudoautosomal homeobox-containing osteogenic protein).

EEA1_MOUSE
θ value	2.36792 (rank : 67)	NC score	0.013721 (rank : 158)
Query Neighborhood Hits	130	Target Neighborhood Hits	1637	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

GSCR2_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.046762 (rank : 108)
Query Neighborhood Hits	130	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZM5, Q9BTC6, Q9HAX6, Q9NPP1, Q9NPR4, Q9UFI2	Gene names	GLTSCR2
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 2 protein (p60).

NCOA6_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.042960 (rank : 111)
Query Neighborhood Hits	130	Target Neighborhood Hits	1202	Shared Neighborhood Hits	47
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

RPGF1_HUMAN
θ value	2.36792 (rank : 70)	NC score	0.016805 (rank : 151)
Query Neighborhood Hits	130	Target Neighborhood Hits	262	Shared Neighborhood Hits	10
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

RX_MOUSE
θ value	2.36792 (rank : 71)	NC score	0.066813 (rank : 50)
Query Neighborhood Hits	130	Target Neighborhood Hits	429	Shared Neighborhood Hits	52
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

TBC10_MOUSE
θ value	2.36792 (rank : 72)	NC score	0.032028 (rank : 124)
Query Neighborhood Hits	130	Target Neighborhood Hits	94	Shared Neighborhood Hits	9
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

BOC_HUMAN
θ value	3.0926 (rank : 73)	NC score	0.005240 (rank : 173)
Query Neighborhood Hits	130	Target Neighborhood Hits	543	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

COG8_MOUSE
θ value	3.0926 (rank : 74)	NC score	0.023955 (rank : 137)
Query Neighborhood Hits	130	Target Neighborhood Hits	147	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

EP400_MOUSE
θ value	3.0926 (rank : 75)	NC score	0.024996 (rank : 135)
Query Neighborhood Hits	130	Target Neighborhood Hits	592	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

IZUM1_MOUSE
θ value	3.0926 (rank : 76)	NC score	0.025049 (rank : 133)
Query Neighborhood Hits	130	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D9J7	Gene names	Izumo1
Domain Architecture	No domain graphic available
Description	Izumo sperm-egg fusion protein 1 precursor (Sperm-specific protein izumo).

MLL3_HUMAN
θ value	3.0926 (rank : 77)	NC score	0.030596 (rank : 127)
Query Neighborhood Hits	130	Target Neighborhood Hits	1644	Shared Neighborhood Hits	53
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MLL4_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.027640 (rank : 130)
Query Neighborhood Hits	130	Target Neighborhood Hits	722	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

NEB1_HUMAN
θ value	3.0926 (rank : 79)	NC score	0.014044 (rank : 157)
Query Neighborhood Hits	130	Target Neighborhood Hits	829	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

NFAT5_HUMAN
θ value	3.0926 (rank : 80)	NC score	0.023147 (rank : 138)
Query Neighborhood Hits	130	Target Neighborhood Hits	217	Shared Neighborhood Hits	20
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

NIPBL_HUMAN
θ value	3.0926 (rank : 81)	NC score	0.024784 (rank : 136)
Query Neighborhood Hits	130	Target Neighborhood Hits	1311	Shared Neighborhood Hits	29
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PCQAP_MOUSE
θ value	3.0926 (rank : 82)	NC score	0.039332 (rank : 114)
Query Neighborhood Hits	130	Target Neighborhood Hits	506	Shared Neighborhood Hits	21
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

PHF14_MOUSE
θ value	3.0926 (rank : 83)	NC score	0.026117 (rank : 132)
Query Neighborhood Hits	130	Target Neighborhood Hits	342	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PO6F2_MOUSE
θ value	3.0926 (rank : 84)	NC score	0.060444 (rank : 55)
Query Neighborhood Hits	130	Target Neighborhood Hits	639	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

TSH1_HUMAN
θ value	3.0926 (rank : 85)	NC score	0.015775 (rank : 152)
Query Neighborhood Hits	130	Target Neighborhood Hits	558	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZSZ6, O60534, Q4LE29, Q53EU4	Gene names	TSHZ1, SDCCAG33, TSH1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3) (Antigen NY-CO-33).

US6NL_MOUSE
θ value	3.0926 (rank : 86)	NC score	0.022084 (rank : 143)
Query Neighborhood Hits	130	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

WIRE_MOUSE
θ value	3.0926 (rank : 87)	NC score	0.039533 (rank : 112)
Query Neighborhood Hits	130	Target Neighborhood Hits	310	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

CRK_HUMAN
θ value	4.03905 (rank : 88)	NC score	0.014267 (rank : 156)
Query Neighborhood Hits	130	Target Neighborhood Hits	308	Shared Neighborhood Hits	7
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

CUTL2_MOUSE
θ value	4.03905 (rank : 89)	NC score	0.114192 (rank : 11)
Query Neighborhood Hits	130	Target Neighborhood Hits	771	Shared Neighborhood Hits	55
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

LMX1A_HUMAN
θ value	4.03905 (rank : 90)	NC score	0.059473 (rank : 60)
Query Neighborhood Hits	130	Target Neighborhood Hits	406	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TE12, Q8TE11	Gene names	LMX1A
Domain Architecture
Description	LIM homeobox transcription factor 1 alpha (LIM/homeobox protein LMX1A) (LIM-homeobox protein 1.1) (LMX-1.1).

MLL2_HUMAN
θ value	4.03905 (rank : 91)	NC score	0.025001 (rank : 134)
Query Neighborhood Hits	130	Target Neighborhood Hits	1788	Shared Neighborhood Hits	46
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PO2F1_MOUSE
θ value	4.03905 (rank : 92)	NC score	0.046026 (rank : 109)
Query Neighborhood Hits	130	Target Neighborhood Hits	408	Shared Neighborhood Hits	52
SwissProt Accessions	P25425, Q61994, Q63891, Q6Y681, Q7TSD0, Q8BT04, Q8K570, Q99JH0, Q9WTZ4, Q9WTZ5, Q9WTZ6	Gene names	Pou2f1, Oct-1, Otf-1, Otf1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

SAMH1_MOUSE
θ value	4.03905 (rank : 93)	NC score	0.039284 (rank : 115)
Query Neighborhood Hits	130	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q60710, Q91VK8	Gene names	Samhd1, Mg11
Domain Architecture
Description	SAM domain and HD domain-containing protein 1 (Interferon-gamma- inducible protein Mg11).

TNKS1_HUMAN
θ value	4.03905 (rank : 94)	NC score	0.006333 (rank : 171)
Query Neighborhood Hits	130	Target Neighborhood Hits	477	Shared Neighborhood Hits	8
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

VSX1_HUMAN
θ value	4.03905 (rank : 95)	NC score	0.075669 (rank : 33)
Query Neighborhood Hits	130	Target Neighborhood Hits	344	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NZR4, Q5TF40, Q5TF41, Q9HCU3, Q9NU27	Gene names	VSX1, RINX
Domain Architecture
Description	Visual system homeobox 1 (Transcription factor VSX1) (Retinal inner nuclear layer homeobox protein) (Homeodomain protein RINX).

ANDR_MOUSE
θ value	5.27518 (rank : 96)	NC score	0.008445 (rank : 166)
Query Neighborhood Hits	130	Target Neighborhood Hits	133	Shared Neighborhood Hits	8
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

ASPP2_HUMAN
θ value	5.27518 (rank : 97)	NC score	0.011427 (rank : 163)
Query Neighborhood Hits	130	Target Neighborhood Hits	1156	Shared Neighborhood Hits	25
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

CI079_HUMAN
θ value	5.27518 (rank : 98)	NC score	0.031216 (rank : 126)
Query Neighborhood Hits	130	Target Neighborhood Hits	288	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

CO5A3_HUMAN
θ value	5.27518 (rank : 99)	NC score	0.007951 (rank : 168)
Query Neighborhood Hits	130	Target Neighborhood Hits	433	Shared Neighborhood Hits	13
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

LHX8_MOUSE
θ value	5.27518 (rank : 100)	NC score	0.062895 (rank : 52)
Query Neighborhood Hits	130	Target Neighborhood Hits	406	Shared Neighborhood Hits	49
SwissProt Accessions	O35652, O70163, O88707	Gene names	Lhx8, Lhx7
Domain Architecture
Description	LIM/homeobox protein Lhx8 (LIM homeodomain Lhx7) (L3).

NCOA6_MOUSE
θ value	5.27518 (rank : 101)	NC score	0.037845 (rank : 116)
Query Neighborhood Hits	130	Target Neighborhood Hits	1076	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

PI3R5_HUMAN
θ value	5.27518 (rank : 102)	NC score	0.021547 (rank : 144)
Query Neighborhood Hits	130	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WYR1, Q5G936, Q5G938, Q5G939, Q8IZ23, Q9Y2Y2	Gene names	PIK3R5
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p101 subunit) (PtdIns-3-kinase p101) (p101- PI3K) (Phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit) (PtdIns-3-kinase regulatory subunit) (Protein FOAP-2).

SALL3_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.005138 (rank : 174)
Query Neighborhood Hits	130	Target Neighborhood Hits	1066	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

SYNJ1_HUMAN
θ value	5.27518 (rank : 104)	NC score	0.013135 (rank : 159)
Query Neighborhood Hits	130	Target Neighborhood Hits	498	Shared Neighborhood Hits	30
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

USP9X_HUMAN
θ value	5.27518 (rank : 105)	NC score	0.007611 (rank : 169)
Query Neighborhood Hits	130	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

WIRE_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.033797 (rank : 123)
Query Neighborhood Hits	130	Target Neighborhood Hits	329	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

3BP1_HUMAN
θ value	6.88961 (rank : 107)	NC score	0.011258 (rank : 164)
Query Neighborhood Hits	130	Target Neighborhood Hits	376	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ARX_HUMAN
θ value	6.88961 (rank : 108)	NC score	0.059207 (rank : 61)
Query Neighborhood Hits	130	Target Neighborhood Hits	401	Shared Neighborhood Hits	49
SwissProt Accessions	Q96QS3	Gene names	ARX
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

ARX_MOUSE
θ value	6.88961 (rank : 109)	NC score	0.059018 (rank : 63)
Query Neighborhood Hits	130	Target Neighborhood Hits	398	Shared Neighborhood Hits	48
SwissProt Accessions	O35085, Q9QYT4	Gene names	Arx
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

COE4_HUMAN
θ value	6.88961 (rank : 110)	NC score	0.007187 (rank : 170)
Query Neighborhood Hits	130	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQW3, Q5JY53, Q9NUB6, Q9P2A6	Gene names	EBF4, COE4, KIAA1442
Domain Architecture
Description	Transcription factor COE4 (Early B-cell factor 4) (EBF-4) (Olf-1/EBF- like 4) (OE-4) (O/E-4).

GAK12_HUMAN
θ value	6.88961 (rank : 111)	NC score	0.008309 (rank : 167)
Query Neighborhood Hits	130	Target Neighborhood Hits	374	Shared Neighborhood Hits	24
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

HESX1_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.070029 (rank : 44)
Query Neighborhood Hits	130	Target Neighborhood Hits	326	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UBX0, Q99667	Gene names	HESX1, HANF
Domain Architecture
Description	Homeobox expressed in ES cells 1 (Homeobox protein ANF) (hAnf).

KPBB_HUMAN
θ value	6.88961 (rank : 113)	NC score	0.015400 (rank : 154)
Query Neighborhood Hits	130	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q93100, Q8N4T5	Gene names	PHKB
Domain Architecture
Description	Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta).

MAML3_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.019235 (rank : 147)
Query Neighborhood Hits	130	Target Neighborhood Hits	323	Shared Neighborhood Hits	16
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

MINT_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.017746 (rank : 149)
Query Neighborhood Hits	130	Target Neighborhood Hits	1291	Shared Neighborhood Hits	35
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

N4BP3_HUMAN
θ value	6.88961 (rank : 116)	NC score	0.011711 (rank : 162)
Query Neighborhood Hits	130	Target Neighborhood Hits	156	Shared Neighborhood Hits	5
SwissProt Accessions	O15049, Q7Z6I3	Gene names	N4BP3, KIAA0341
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

TENX_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.004022 (rank : 176)
Query Neighborhood Hits	130	Target Neighborhood Hits	789	Shared Neighborhood Hits	11
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

ZN342_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.001549 (rank : 179)
Query Neighborhood Hits	130	Target Neighborhood Hits	705	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WUU4	Gene names	ZNF342
Domain Architecture	No domain graphic available
Description	Zinc finger protein 342.

ZN516_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.003373 (rank : 177)
Query Neighborhood Hits	130	Target Neighborhood Hits	1197	Shared Neighborhood Hits	32
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

AKAP6_HUMAN
θ value	8.99809 (rank : 120)	NC score	0.012572 (rank : 160)
Query Neighborhood Hits	130	Target Neighborhood Hits	263	Shared Neighborhood Hits	9
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

CAC1G_HUMAN
θ value	8.99809 (rank : 121)	NC score	0.005517 (rank : 172)
Query Neighborhood Hits	130	Target Neighborhood Hits	587	Shared Neighborhood Hits	20
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

DLG5_HUMAN
θ value	8.99809 (rank : 122)	NC score	0.010122 (rank : 165)
Query Neighborhood Hits	130	Target Neighborhood Hits	1088	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DMRTC_MOUSE
θ value	8.99809 (rank : 123)	NC score	0.022534 (rank : 141)
Query Neighborhood Hits	130	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D9R7, Q2PMY0, Q9D5U3	Gene names	Dmrtc1, Dmrt8.1
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C1 (Doublesex- and mab-3-related transcription factor 8.1).

DNMBP_MOUSE
θ value	8.99809 (rank : 124)	NC score	0.015085 (rank : 155)
Query Neighborhood Hits	130	Target Neighborhood Hits	435	Shared Neighborhood Hits	10
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

HAP1_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.021183 (rank : 145)
Query Neighborhood Hits	130	Target Neighborhood Hits	388	Shared Neighborhood Hits	14
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

KSR1_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.000744 (rank : 180)
Query Neighborhood Hits	130	Target Neighborhood Hits	867	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

LMX1A_MOUSE
θ value	8.99809 (rank : 127)	NC score	0.055047 (rank : 81)
Query Neighborhood Hits	130	Target Neighborhood Hits	405	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JKU8	Gene names	Lmx1a
Domain Architecture
Description	LIM homeobox transcription factor 1 alpha (LIM/homeobox protein LMX1A) (LIM-homeobox protein 1.1) (LMX-1.1).

MBD6_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.022991 (rank : 139)
Query Neighborhood Hits	130	Target Neighborhood Hits	349	Shared Neighborhood Hits	21
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

PAX4_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.065281 (rank : 51)
Query Neighborhood Hits	130	Target Neighborhood Hits	367	Shared Neighborhood Hits	49
SwissProt Accessions	O43316, O95161, Q6B0H0	Gene names	PAX4
Domain Architecture
Description	Paired box protein Pax-4.

PRR3_MOUSE
θ value	8.99809 (rank : 130)	NC score	0.022660 (rank : 140)
Query Neighborhood Hits	130	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q811B5, Q91YI5	Gene names	Prr3, Cat56
Domain Architecture	No domain graphic available
Description	Proline-rich protein 3 (MHC class I region proline-rich protein CAT56).

CART1_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.055628 (rank : 71)
Query Neighborhood Hits	130	Target Neighborhood Hits	348	Shared Neighborhood Hits	43
SwissProt Accessions	Q15699, Q546C8, Q96FH4	Gene names	CART1
Domain Architecture
Description	Cartilage homeoprotein 1 (CART-1).

CART1_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.055533 (rank : 72)
Query Neighborhood Hits	130	Target Neighborhood Hits	344	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C8B0, Q8C370	Gene names	Cart1
Domain Architecture	No domain graphic available
Description	Cartilage homeoprotein 1 (CART-1).

CRX_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.055111 (rank : 79)
Query Neighborhood Hits	130	Target Neighborhood Hits	360	Shared Neighborhood Hits	49
SwissProt Accessions	O43186	Gene names	CRX, CORD2
Domain Architecture
Description	Cone-rod homeobox protein.

CRX_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.055184 (rank : 77)
Query Neighborhood Hits	130	Target Neighborhood Hits	359	Shared Neighborhood Hits	48
SwissProt Accessions	O54751	Gene names	Crx
Domain Architecture
Description	Cone-rod homeobox protein.

DUX1_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.057000 (rank : 68)
Query Neighborhood Hits	130	Target Neighborhood Hits	330	Shared Neighborhood Hits	46
SwissProt Accessions	O43812	Gene names	DUX1
Domain Architecture	No domain graphic available
Description	Double homeobox protein 1.

DUX2_HUMAN
θ value	θ > 10 (rank : 136)	NC score	0.060032 (rank : 57)
Query Neighborhood Hits	130	Target Neighborhood Hits	173	Shared Neighborhood Hits	41
SwissProt Accessions	O75505	Gene names	DUX2
Domain Architecture	No domain graphic available
Description	Putative double homeobox protein 2.

DUX3_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.054952 (rank : 82)
Query Neighborhood Hits	130	Target Neighborhood Hits	312	Shared Neighborhood Hits	46
SwissProt Accessions	Q96PT4, Q9UND2	Gene names	DUX3
Domain Architecture	No domain graphic available
Description	Putative double homeobox protein 3.

DUX4_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.055363 (rank : 74)
Query Neighborhood Hits	130	Target Neighborhood Hits	403	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UBX2	Gene names	DUX4, DUX10
Domain Architecture	No domain graphic available
Description	Double homeobox protein 4 (Double homeobox protein 10) (Double homeobox protein 4/10).

DUX5_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.056822 (rank : 69)
Query Neighborhood Hits	130	Target Neighborhood Hits	330	Shared Neighborhood Hits	46
SwissProt Accessions	Q96PT3	Gene names	DUX5
Domain Architecture	No domain graphic available
Description	Double homeobox protein 5.

GSCL_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.059143 (rank : 62)
Query Neighborhood Hits	130	Target Neighborhood Hits	343	Shared Neighborhood Hits	46
SwissProt Accessions	O15499	Gene names	GSCL
Domain Architecture
Description	Homeobox protein goosecoid-like (GSC-2).

GSCL_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.060884 (rank : 54)
Query Neighborhood Hits	130	Target Neighborhood Hits	339	Shared Neighborhood Hits	46
SwissProt Accessions	P56916	Gene names	Gscl
Domain Architecture	No domain graphic available
Description	Homeobox protein goosecoid-like (GSC-2).

GSC_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.057884 (rank : 66)
Query Neighborhood Hits	130	Target Neighborhood Hits	369	Shared Neighborhood Hits	48
SwissProt Accessions	P56915, Q86YR1	Gene names	GSC
Domain Architecture	No domain graphic available
Description	Homeobox protein goosecoid.

GSC_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.058028 (rank : 65)
Query Neighborhood Hits	130	Target Neighborhood Hits	368	Shared Neighborhood Hits	48
SwissProt Accessions	Q02591	Gene names	Gsc
Domain Architecture
Description	Homeobox protein goosecoid.

LHX3_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.054836 (rank : 84)
Query Neighborhood Hits	130	Target Neighborhood Hits	474	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UBR4, Q9NZB5, Q9P0I8, Q9P0I9	Gene names	LHX3
Domain Architecture
Description	LIM/homeobox protein Lhx3.

LHX3_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.054708 (rank : 85)
Query Neighborhood Hits	130	Target Neighborhood Hits	451	Shared Neighborhood Hits	51
SwissProt Accessions	P50481, Q61800, Q61801	Gene names	Lhx3, Lim-3, Lim3, Plim
Domain Architecture
Description	LIM/homeobox protein Lhx3 (Homeobox protein LIM-3) (Homeobox protein P-LIM) (LIM homeobox protein 3).

LHX4_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.053843 (rank : 90)
Query Neighborhood Hits	130	Target Neighborhood Hits	455	Shared Neighborhood Hits	49
SwissProt Accessions	Q969G2, Q8NHE0, Q8TCJ1, Q8WWX2, Q969W2	Gene names	LHX4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

LHX4_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.053575 (rank : 93)
Query Neighborhood Hits	130	Target Neighborhood Hits	457	Shared Neighborhood Hits	49
SwissProt Accessions	P53776, O08916, Q9R280	Gene names	Lhx4, Gsh-4, Gsh4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

LMX1B_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.051842 (rank : 103)
Query Neighborhood Hits	130	Target Neighborhood Hits	404	Shared Neighborhood Hits	46
SwissProt Accessions	O60663, O75463	Gene names	LMX1B
Domain Architecture
Description	LIM homeobox transcription factor 1 beta (LIM/homeobox protein LMX1B) (LIM-homeobox protein 1.2) (LMX-1.2).

LMX1B_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.051726 (rank : 104)
Query Neighborhood Hits	130	Target Neighborhood Hits	394	Shared Neighborhood Hits	46
SwissProt Accessions	O88609	Gene names	Lmx1b
Domain Architecture
Description	LIM homeobox transcription factor 1 beta (LIM/homeobox protein LMX1B) (LIM-homeobox protein 1.2) (LMX-1.2).

OTP_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.055081 (rank : 80)
Query Neighborhood Hits	130	Target Neighborhood Hits	387	Shared Neighborhood Hits	47
SwissProt Accessions	O09113	Gene names	Otp
Domain Architecture
Description	Homeobox protein orthopedia.

OTX1_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.061382 (rank : 53)
Query Neighborhood Hits	130	Target Neighborhood Hits	379	Shared Neighborhood Hits	53
SwissProt Accessions	P32242, Q53TG6	Gene names	OTX1
Domain Architecture
Description	Homeobox protein OTX1.

OTX1_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.060012 (rank : 58)
Query Neighborhood Hits	130	Target Neighborhood Hits	372	Shared Neighborhood Hits	51
SwissProt Accessions	P80205	Gene names	Otx1, Otx-1
Domain Architecture
Description	Homeobox protein OTX1.

OTX2_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.053325 (rank : 95)
Query Neighborhood Hits	130	Target Neighborhood Hits	341	Shared Neighborhood Hits	44
SwissProt Accessions	P32243, Q6GTV3, Q9HAW3, Q9P2R1	Gene names	OTX2
Domain Architecture
Description	Homeobox protein OTX2.

OTX2_MOUSE
θ value	θ > 10 (rank : 154)	NC score	0.053360 (rank : 94)
Query Neighborhood Hits	130	Target Neighborhood Hits	345	Shared Neighborhood Hits	45
SwissProt Accessions	P80206	Gene names	Otx2, Otx-2
Domain Architecture
Description	Homeobox protein OTX2.

PAX3_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.055390 (rank : 73)
Query Neighborhood Hits	130	Target Neighborhood Hits	513	Shared Neighborhood Hits	55
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

PAX3_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.055163 (rank : 78)
Query Neighborhood Hits	130	Target Neighborhood Hits	478	Shared Neighborhood Hits	54
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

PAX7_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.054845 (rank : 83)
Query Neighborhood Hits	130	Target Neighborhood Hits	456	Shared Neighborhood Hits	53
SwissProt Accessions	P23759	Gene names	PAX7, HUP1
Domain Architecture
Description	Paired box protein Pax-7 (HUP1).

PAX7_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.054604 (rank : 86)
Query Neighborhood Hits	130	Target Neighborhood Hits	422	Shared Neighborhood Hits	51
SwissProt Accessions	P47239, Q9ES16	Gene names	Pax7, Pax-7
Domain Architecture	No domain graphic available
Description	Paired box protein Pax-7.

PEPP2_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.051539 (rank : 105)
Query Neighborhood Hits	130	Target Neighborhood Hits	316	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BQY4, Q9BR00	Gene names	PEPP2, THG1
Domain Architecture
Description	Paired-like homeobox protein PEPP-2 (Testis homeobox gene 1).

PHX2A_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.053691 (rank : 91)
Query Neighborhood Hits	130	Target Neighborhood Hits	345	Shared Neighborhood Hits	45
SwissProt Accessions	O14813, Q8IVZ2	Gene names	PHOX2A, ARIX, PMX2A
Domain Architecture
Description	Paired mesoderm homeobox protein 2A (Paired-like homeobox 2A) (Aristaless homeobox protein homolog) (ARIX1 homeodomain protein).

PHX2A_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.053690 (rank : 92)
Query Neighborhood Hits	130	Target Neighborhood Hits	338	Shared Neighborhood Hits	45
SwissProt Accessions	Q62066	Gene names	Phox2a, Arix, Phox2, Pmx2, Pmx2a
Domain Architecture
Description	Paired mesoderm homeobox protein 2A (Paired-like homeobox 2A) (PHOX2A homeodomain protein) (Aristaless homeobox protein homolog).

PHX2B_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.053007 (rank : 96)
Query Neighborhood Hits	130	Target Neighborhood Hits	407	Shared Neighborhood Hits	47
SwissProt Accessions	Q99453, Q6PJD9	Gene names	PHOX2B, PMX2B
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

PHX2B_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.053007 (rank : 97)
Query Neighborhood Hits	130	Target Neighborhood Hits	407	Shared Neighborhood Hits	47
SwissProt Accessions	O35690	Gene names	Phox2b, Pmx2b
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

PITX1_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.051849 (rank : 102)
Query Neighborhood Hits	130	Target Neighborhood Hits	353	Shared Neighborhood Hits	45
SwissProt Accessions	P78337, O14677, O60425, Q9BTI5	Gene names	PITX1, BFT, PTX1
Domain Architecture
Description	Pituitary homeobox 1 (Hindlimb expressed homeobox protein backfoot).

PITX1_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.051505 (rank : 106)
Query Neighborhood Hits	130	Target Neighborhood Hits	362	Shared Neighborhood Hits	45
SwissProt Accessions	P70314, O54742, P70427	Gene names	Pitx1, Bft, Potx, Ptx1
Domain Architecture
Description	Pituitary homeobox 1 (Homeobox protein P-OTX) (Pituitary OTX-related factor) (Hindlimb expressed homeobox protein backfoot) (Ptx1).

PITX2_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.052431 (rank : 100)
Query Neighborhood Hits	130	Target Neighborhood Hits	381	Shared Neighborhood Hits	46
SwissProt Accessions	Q99697, O60578, O60579, O60580, Q9BY17	Gene names	PITX2, ARP1, RGS, RIEG, RIEG1
Domain Architecture
Description	Pituitary homeobox 2 (RIEG bicoid-related homeobox transcription factor) (Solurshin) (ALL1-responsive protein ARP1).

PITX2_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.052083 (rank : 101)
Query Neighborhood Hits	130	Target Neighborhood Hits	383	Shared Neighborhood Hits	46
SwissProt Accessions	P97474, O08646, O70336, P97933, Q9JLA0, Q9QXB8, Q9R1V9, Q9Z141	Gene names	Pitx2, Arp1, Brx1, Otlx2, Ptx2, Rgs
Domain Architecture
Description	Pituitary homeobox 2 (Orthodenticle-like homeobox 2) (Solurshin) (ALL1-responsive protein ARP1) (BRX1 homeoprotein) (Paired-like homeodomain transcription factor Munc 30).

PITX3_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.052832 (rank : 99)
Query Neighborhood Hits	130	Target Neighborhood Hits	366	Shared Neighborhood Hits	47
SwissProt Accessions	O75364	Gene names	PITX3, PTX3
Domain Architecture
Description	Pituitary homeobox 3 (Homeobox protein PITX3).

PITX3_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.052833 (rank : 98)
Query Neighborhood Hits	130	Target Neighborhood Hits	380	Shared Neighborhood Hits	49
SwissProt Accessions	O35160	Gene names	Pitx3
Domain Architecture
Description	Pituitary homeobox 3 (Homeobox protein PITX3).

PO6F2_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.051048 (rank : 107)
Query Neighborhood Hits	130	Target Neighborhood Hits	618	Shared Neighborhood Hits	61
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PROP1_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.060405 (rank : 56)
Query Neighborhood Hits	130	Target Neighborhood Hits	354	Shared Neighborhood Hits	46
SwissProt Accessions	O75360	Gene names	PROP1
Domain Architecture
Description	Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary-specific homeodomain factor).

PROP1_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.060007 (rank : 59)
Query Neighborhood Hits	130	Target Neighborhood Hits	361	Shared Neighborhood Hits	47
SwissProt Accessions	P97458	Gene names	Prop1, Prop-1
Domain Architecture
Description	Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary-specific homeodomain factor).

PRRX1_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.055303 (rank : 76)
Query Neighborhood Hits	130	Target Neighborhood Hits	347	Shared Neighborhood Hits	45
SwissProt Accessions	P54821, O60807	Gene names	PRRX1, PMX1
Domain Architecture
Description	Paired mesoderm homeobox protein 1 (PRX-1) (Paired-related homeobox protein 1) (Homeobox protein PHOX1).

PRRX1_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.055326 (rank : 75)
Query Neighborhood Hits	130	Target Neighborhood Hits	346	Shared Neighborhood Hits	45
SwissProt Accessions	P63013, P43271, Q02810	Gene names	Prrx1, Pmx, Pmx1
Domain Architecture	No domain graphic available
Description	Paired mesoderm homeobox protein 1 (PRX-1) (Paired-related homeobox protein 1) (Homeobox protein mHox) (Homeobox protein K-2).

PRRX2_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.056741 (rank : 70)
Query Neighborhood Hits	130	Target Neighborhood Hits	348	Shared Neighborhood Hits	45
SwissProt Accessions	Q99811, Q9UIB3	Gene names	PRRX2, PMX2, PRX2
Domain Architecture
Description	Paired mesoderm homeobox protein 2 (PRX-2) (Paired-related homeobox protein 2).

PRRX2_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.057059 (rank : 67)
Query Neighborhood Hits	130	Target Neighborhood Hits	351	Shared Neighborhood Hits	45
SwissProt Accessions	Q06348, Q61651	Gene names	Prrx2, Prx2, S8
Domain Architecture
Description	Paired mesoderm homeobox protein 2 (PRX-2) (Homeobox protein S8).

PRRXL_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.058682 (rank : 64)
Query Neighborhood Hits	130	Target Neighborhood Hits	350	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BYH0, Q8K3F8	Gene names	Prrxl1, Drg11
Domain Architecture	No domain graphic available
Description	Paired-related homeobox protein-like 1 (Dorsal root ganglion 11) (Homeobox protein DRG11).

ZHX1_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.054311 (rank : 87)
Query Neighborhood Hits	130	Target Neighborhood Hits	307	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UKY1, Q8IWD8	Gene names	ZHX1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

ZHX1_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.053976 (rank : 89)
Query Neighborhood Hits	130	Target Neighborhood Hits	334	Shared Neighborhood Hits	47
SwissProt Accessions	P70121, Q8BQ68, Q8C6T4, Q8CJG3	Gene names	Zhx1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

ZHX2_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.054161 (rank : 88)
Query Neighborhood Hits	130	Target Neighborhood Hits	347	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y6X8	Gene names	ZHX2, AFR1, KIAA0854, RAF
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

Hits sorted by NC score

SATB1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	130	Target Neighborhood Hits	130	Shared Neighborhood Hits	130
SwissProt Accessions	Q60611	Gene names	Satb1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

SATB1_HUMAN
NC score	0.992823 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	130	Target Neighborhood Hits	130	Shared Neighborhood Hits	104
SwissProt Accessions	Q01826	Gene names	SATB1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

SATB2_HUMAN
NC score	0.970475 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	130	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UPW6	Gene names	SATB2, KIAA1034
Domain Architecture
Description	DNA-binding protein SATB2 (Special AT-rich sequence-binding protein 2).

SATB2_MOUSE
NC score	0.970383 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	130	Target Neighborhood Hits	58	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VI24	Gene names	Satb2, Kiaa1034
Domain Architecture
Description	DNA-binding protein SATB2 (Special AT-rich sequence-binding protein 2).

ONEC2_HUMAN
NC score	0.279328 (rank : 5)	θ value	7.1131e-05 (rank : 5)
Query Neighborhood Hits	130	Target Neighborhood Hits	115	Shared Neighborhood Hits	31
SwissProt Accessions	O95948	Gene names	ONECUT2
Domain Architecture
Description	One cut domain family member 2 (Transcription factor ONECUT-2) (OC-2).

ONEC2_MOUSE
NC score	0.277212 (rank : 6)	θ value	7.1131e-05 (rank : 6)
Query Neighborhood Hits	130	Target Neighborhood Hits	123	Shared Neighborhood Hits	29
SwissProt Accessions	Q6XBJ3	Gene names	Onecut2, Oc2
Domain Architecture	No domain graphic available
Description	One cut domain family member 2 (Transcription factor ONECUT-2) (OC-2).

HNF6_MOUSE
NC score	0.270711 (rank : 7)	θ value	0.00020696 (rank : 8)
Query Neighborhood Hits	130	Target Neighborhood Hits	124	Shared Neighborhood Hits	29
SwissProt Accessions	O08755	Gene names	Onecut1, Hnf6, Hnf6a
Domain Architecture
Description	Hepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1).

HNF6_HUMAN
NC score	0.270438 (rank : 8)	θ value	0.00020696 (rank : 7)
Query Neighborhood Hits	130	Target Neighborhood Hits	127	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UBC0, Q99744, Q9UMR6	Gene names	ONECUT1, HNF6, HNF6A
Domain Architecture
Description	Hepatocyte nuclear factor 6 (HNF-6) (One cut domain family member 1).

HOMEZ_MOUSE
NC score	0.154395 (rank : 9)	θ value	0.0736092 (rank : 17)
Query Neighborhood Hits	130	Target Neighborhood Hits	61	Shared Neighborhood Hits	12
SwissProt Accessions	Q80W88	Gene names	Homez, Kiaa1443
Domain Architecture
Description	Homeobox and leucine zipper protein Homez (Homeodomain leucine zipper- containing factor).

HOMEZ_HUMAN
NC score	0.130329 (rank : 10)	θ value	0.0736092 (rank : 16)
Query Neighborhood Hits	130	Target Neighborhood Hits	110	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IX15, Q6P049, Q86XB6, Q9P2A5	Gene names	HOMEZ, KIAA1443
Domain Architecture
Description	Homeobox and leucine zipper protein Homez (Homeodomain leucine zipper- containing factor).

CUTL2_MOUSE
NC score	0.114192 (rank : 11)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	130	Target Neighborhood Hits	771	Shared Neighborhood Hits	55
SwissProt Accessions	P70298	Gene names	Cutl2
Domain Architecture
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

ATBF1_HUMAN
NC score	0.112864 (rank : 12)	θ value	0.0148317 (rank : 12)
Query Neighborhood Hits	130	Target Neighborhood Hits	1547	Shared Neighborhood Hits	77
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

ATBF1_MOUSE
NC score	0.111592 (rank : 13)	θ value	0.00665767 (rank : 10)
Query Neighborhood Hits	130	Target Neighborhood Hits	1841	Shared Neighborhood Hits	84
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CUTL2_HUMAN
NC score	0.110888 (rank : 14)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	130	Target Neighborhood Hits	906	Shared Neighborhood Hits	58
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

ZFHX2_HUMAN
NC score	0.109798 (rank : 15)	θ value	0.0330416 (rank : 15)
Query Neighborhood Hits	130	Target Neighborhood Hits	1178	Shared Neighborhood Hits	69
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

VSX1_MOUSE
NC score	0.097239 (rank : 16)	θ value	0.21417 (rank : 26)
Query Neighborhood Hits	130	Target Neighborhood Hits	356	Shared Neighborhood Hits	49
SwissProt Accessions	Q91V10	Gene names	Vsx1, Rinx
Domain Architecture
Description	Visual system homeobox 1 (Transcription factor VSX1) (Retinal inner nuclear layer homeobox protein) (Homeodomain protein RINX).

ESX1L_HUMAN
NC score	0.094117 (rank : 17)	θ value	0.21417 (rank : 23)
Query Neighborhood Hits	130	Target Neighborhood Hits	498	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N693, Q7Z6K7	Gene names	ESX1L, ESX1R
Domain Architecture
Description	Extraembryonic, spermatogenesis, homeobox 1-like protein.

SHOX2_HUMAN
NC score	0.093848 (rank : 18)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	130	Target Neighborhood Hits	353	Shared Neighborhood Hits	52
SwissProt Accessions	O60902, O60465, O60467, O60903	Gene names	SHOX2, OG12X, SHOT
Domain Architecture
Description	Short stature homeobox protein 2 (Paired-related homeobox protein SHOT) (Homeobox protein Og12X).

LHX6_MOUSE
NC score	0.091689 (rank : 19)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	130	Target Neighborhood Hits	399	Shared Neighborhood Hits	50
SwissProt Accessions	O88706	Gene names	Lhx6
Domain Architecture
Description	LIM/homeobox protein Lhx6.

SHOX2_MOUSE
NC score	0.091639 (rank : 20)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	130	Target Neighborhood Hits	348	Shared Neighborhood Hits	52
SwissProt Accessions	P70390, P70369	Gene names	Shox2, Og12x, Prx3
Domain Architecture
Description	Short stature homeobox protein 2 (Homeobox protein Og12X) (OG-12) (Paired family homeodomain protein Prx3).

LHX61_HUMAN
NC score	0.089044 (rank : 21)	θ value	0.163984 (rank : 19)
Query Neighborhood Hits	130	Target Neighborhood Hits	412	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UPM6, Q5T7S8, Q9NTK3, Q9UPM5	Gene names	LHX6, LHX6.1
Domain Architecture
Description	LIM/homeobox protein Lhx6.1 (Lhx6).

SHOX_HUMAN
NC score	0.085818 (rank : 22)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	130	Target Neighborhood Hits	363	Shared Neighborhood Hits	54
SwissProt Accessions	O15266, O00412, O00413, O15267	Gene names	SHOX, PHOG
Domain Architecture
Description	Short stature homeobox protein (Short stature homeobox-containing protein) (Pseudoautosomal homeobox-containing osteogenic protein).

ZHX2_MOUSE
NC score	0.083249 (rank : 23)	θ value	0.62314 (rank : 38)
Query Neighborhood Hits	130	Target Neighborhood Hits	435	Shared Neighborhood Hits	42
SwissProt Accessions	Q8C0C0	Gene names	Zhx2, Afr1, Raf
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

LHX61_MOUSE
NC score	0.081906 (rank : 24)	θ value	0.47712 (rank : 33)
Query Neighborhood Hits	130	Target Neighborhood Hits	396	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R1R0, Q9R1R1	Gene names	Lhx6.1
Domain Architecture
Description	LIM/homeobox protein Lhx6.1.

PAX6_HUMAN
NC score	0.081261 (rank : 25)	θ value	0.21417 (rank : 24)
Query Neighborhood Hits	130	Target Neighborhood Hits	383	Shared Neighborhood Hits	50
SwissProt Accessions	P26367, Q6N006, Q99413	Gene names	PAX6, AN2
Domain Architecture
Description	Paired box protein Pax-6 (Oculorhombin) (Aniridia type II protein).

PAX6_MOUSE
NC score	0.081261 (rank : 26)	θ value	0.21417 (rank : 25)
Query Neighborhood Hits	130	Target Neighborhood Hits	383	Shared Neighborhood Hits	50
SwissProt Accessions	P63015, P32117, P70601, Q62222, Q64037, Q8CEI5, Q8VDB5, Q921Q8	Gene names	Pax6, Pax-6, Sey
Domain Architecture	No domain graphic available
Description	Paired box protein Pax-6 (Oculorhombin).

CUTL1_HUMAN
NC score	0.079255 (rank : 27)	θ value	0.0193708 (rank : 13)
Query Neighborhood Hits	130	Target Neighborhood Hits	1574	Shared Neighborhood Hits	70
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

TNR6A_HUMAN
NC score	0.078474 (rank : 28)	θ value	0.0330416 (rank : 14)
Query Neighborhood Hits	130	Target Neighborhood Hits	343	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

ZHX3_MOUSE
NC score	0.078108 (rank : 29)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	130	Target Neighborhood Hits	321	Shared Neighborhood Hits	45
SwissProt Accessions	Q8C0Q2, Q80U14	Gene names	Zhx3, Kiaa0395, Tix1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

ZHX3_HUMAN
NC score	0.077253 (rank : 30)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	130	Target Neighborhood Hits	331	Shared Neighborhood Hits	42
SwissProt Accessions	Q9H4I2, O43145	Gene names	ZHX3, KIAA0395, TIX1
Domain Architecture
Description	Zinc finger and homeodomain protein 3 (Triple homeobox protein 1).

BPTF_HUMAN
NC score	0.076291 (rank : 31)	θ value	0.000461057 (rank : 9)
Query Neighborhood Hits	130	Target Neighborhood Hits	786	Shared Neighborhood Hits	25
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

HESX1_MOUSE
NC score	0.076115 (rank : 32)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	130	Target Neighborhood Hits	331	Shared Neighborhood Hits	49
SwissProt Accessions	Q61658, Q61047	Gene names	Hesx1, Hes-1, Rpx
Domain Architecture
Description	Homeobox expressed in ES cells 1 (Homeobox protein ANF) (Anterior- restricted homeobox protein) (Rathke pouch homeo box).

VSX1_HUMAN
NC score	0.075669 (rank : 33)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	130	Target Neighborhood Hits	344	Shared Neighborhood Hits	49
SwissProt Accessions	Q9NZR4, Q5TF40, Q5TF41, Q9HCU3, Q9NU27	Gene names	VSX1, RINX
Domain Architecture
Description	Visual system homeobox 1 (Transcription factor VSX1) (Retinal inner nuclear layer homeobox protein) (Homeodomain protein RINX).

ALX4_MOUSE
NC score	0.075230 (rank : 34)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	130	Target Neighborhood Hits	369	Shared Neighborhood Hits	48
SwissProt Accessions	O35137	Gene names	Alx4
Domain Architecture
Description	Homeobox protein aristaless-like 4 (ALX-4).

HME1_HUMAN
NC score	0.072927 (rank : 35)	θ value	0.365318 (rank : 28)
Query Neighborhood Hits	130	Target Neighborhood Hits	384	Shared Neighborhood Hits	49
SwissProt Accessions	Q05925	Gene names	EN1
Domain Architecture
Description	Homeobox protein engrailed-1 (Hu-En-1).

HME1_MOUSE
NC score	0.072754 (rank : 36)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	130	Target Neighborhood Hits	397	Shared Neighborhood Hits	48
SwissProt Accessions	P09065	Gene names	En1, En-1
Domain Architecture
Description	Homeobox protein engrailed-1 (Mo-En-1).

ALX4_HUMAN
NC score	0.072425 (rank : 37)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	130	Target Neighborhood Hits	394	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H161, Q96JN7, Q9H198, Q9HAY9	Gene names	ALX4, KIAA1788
Domain Architecture
Description	Homeobox protein aristaless-like 4.

PEPP1_HUMAN
NC score	0.072322 (rank : 38)	θ value	0.163984 (rank : 21)
Query Neighborhood Hits	130	Target Neighborhood Hits	338	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NHV9, O95030, Q3SYE0	Gene names	PEPP1, OTEX
Domain Architecture
Description	Paired-like homeobox protein PEPP-1 (Ovary-, testis- and epididymis- expressed gene protein).

CUTL1_MOUSE
NC score	0.071352 (rank : 39)	θ value	0.21417 (rank : 22)
Query Neighborhood Hits	130	Target Neighborhood Hits	1620	Shared Neighborhood Hits	68
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

RX_HUMAN
NC score	0.071251 (rank : 40)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	130	Target Neighborhood Hits	423	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2V3	Gene names	RAX, RX
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

PAX4_MOUSE
NC score	0.070603 (rank : 41)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	130	Target Neighborhood Hits	370	Shared Neighborhood Hits	53
SwissProt Accessions	P32115, P97341, Q9QUR1, Q9R091	Gene names	Pax4, Pax-4
Domain Architecture
Description	Paired box protein Pax-4.

CHX10_MOUSE
NC score	0.070553 (rank : 42)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	130	Target Neighborhood Hits	340	Shared Neighborhood Hits	48
SwissProt Accessions	Q61412	Gene names	Chx10, Vsx2
Domain Architecture
Description	Homeobox protein CHX10 (Ceh-10 homeodomain-containing homolog).

CHX10_HUMAN
NC score	0.070531 (rank : 43)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	130	Target Neighborhood Hits	340	Shared Neighborhood Hits	47
SwissProt Accessions	P58304	Gene names	CHX10, VSX2
Domain Architecture
Description	Homeobox protein CHX10 (Ceh-10 homeodomain-containing homolog).

HESX1_HUMAN
NC score	0.070029 (rank : 44)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	130	Target Neighborhood Hits	326	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UBX0, Q99667	Gene names	HESX1, HANF
Domain Architecture
Description	Homeobox expressed in ES cells 1 (Homeobox protein ANF) (hAnf).

HME2_MOUSE
NC score	0.069702 (rank : 45)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	130	Target Neighborhood Hits	352	Shared Neighborhood Hits	49
SwissProt Accessions	P09066	Gene names	En2, En-2
Domain Architecture
Description	Homeobox protein engrailed-2 (Mo-En-2).

HME2_HUMAN
NC score	0.069364 (rank : 46)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	130	Target Neighborhood Hits	355	Shared Neighborhood Hits	49
SwissProt Accessions	P19622	Gene names	EN2
Domain Architecture
Description	Homeobox protein engrailed-2 (Hu-En-2).

ALX3_HUMAN
NC score	0.068711 (rank : 47)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	130	Target Neighborhood Hits	380	Shared Neighborhood Hits	46
SwissProt Accessions	O95076, O95075	Gene names	ALX3
Domain Architecture
Description	Homeobox protein aristaless-like 3 (Proline-rich transcription factor ALX3).

PO2F1_HUMAN
NC score	0.068593 (rank : 48)	θ value	0.00869519 (rank : 11)
Query Neighborhood Hits	130	Target Neighborhood Hits	426	Shared Neighborhood Hits	56
SwissProt Accessions	P14859, Q5TBT7, Q6PK46, Q8NEU9, Q9BPV1	Gene names	POU2F1, OCT1, OTF1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

ALX3_MOUSE
NC score	0.067891 (rank : 49)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	130	Target Neighborhood Hits	386	Shared Neighborhood Hits	46
SwissProt Accessions	O70137	Gene names	Alx3
Domain Architecture
Description	Homeobox protein aristaless-like 3 (Proline-rich transcription factor ALX3).

RX_MOUSE
NC score	0.066813 (rank : 50)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	130	Target Neighborhood Hits	429	Shared Neighborhood Hits	52
SwissProt Accessions	O35602, O08748	Gene names	Rax, Rx
Domain Architecture
Description	Retinal homeobox protein Rx (Retina and anterior neural fold homeobox protein).

PAX4_HUMAN
NC score	0.065281 (rank : 51)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	130	Target Neighborhood Hits	367	Shared Neighborhood Hits	49
SwissProt Accessions	O43316, O95161, Q6B0H0	Gene names	PAX4
Domain Architecture
Description	Paired box protein Pax-4.

LHX8_MOUSE
NC score	0.062895 (rank : 52)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	130	Target Neighborhood Hits	406	Shared Neighborhood Hits	49
SwissProt Accessions	O35652, O70163, O88707	Gene names	Lhx8, Lhx7
Domain Architecture
Description	LIM/homeobox protein Lhx8 (LIM homeodomain Lhx7) (L3).

OTX1_HUMAN
NC score	0.061382 (rank : 53)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	130	Target Neighborhood Hits	379	Shared Neighborhood Hits	53
SwissProt Accessions	P32242, Q53TG6	Gene names	OTX1
Domain Architecture
Description	Homeobox protein OTX1.

GSCL_MOUSE
NC score	0.060884 (rank : 54)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	130	Target Neighborhood Hits	339	Shared Neighborhood Hits	46
SwissProt Accessions	P56916	Gene names	Gscl
Domain Architecture	No domain graphic available
Description	Homeobox protein goosecoid-like (GSC-2).

PO6F2_MOUSE
NC score	0.060444 (rank : 55)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	130	Target Neighborhood Hits	639	Shared Neighborhood Hits	63
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

PROP1_HUMAN
NC score	0.060405 (rank : 56)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	130	Target Neighborhood Hits	354	Shared Neighborhood Hits	46
SwissProt Accessions	O75360	Gene names	PROP1
Domain Architecture
Description	Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary-specific homeodomain factor).

DUX2_HUMAN
NC score	0.060032 (rank : 57)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	130	Target Neighborhood Hits	173	Shared Neighborhood Hits	41
SwissProt Accessions	O75505	Gene names	DUX2
Domain Architecture	No domain graphic available
Description	Putative double homeobox protein 2.

OTX1_MOUSE
NC score	0.060012 (rank : 58)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	130	Target Neighborhood Hits	372	Shared Neighborhood Hits	51
SwissProt Accessions	P80205	Gene names	Otx1, Otx-1
Domain Architecture
Description	Homeobox protein OTX1.

PROP1_MOUSE
NC score	0.060007 (rank : 59)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	130	Target Neighborhood Hits	361	Shared Neighborhood Hits	47
SwissProt Accessions	P97458	Gene names	Prop1, Prop-1
Domain Architecture
Description	Homeobox protein prophet of Pit-1 (PROP-1) (Pituitary-specific homeodomain factor).

LMX1A_HUMAN
NC score	0.059473 (rank : 60)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	130	Target Neighborhood Hits	406	Shared Neighborhood Hits	47
SwissProt Accessions	Q8TE12, Q8TE11	Gene names	LMX1A
Domain Architecture
Description	LIM homeobox transcription factor 1 alpha (LIM/homeobox protein LMX1A) (LIM-homeobox protein 1.1) (LMX-1.1).

ARX_HUMAN
NC score	0.059207 (rank : 61)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	130	Target Neighborhood Hits	401	Shared Neighborhood Hits	49
SwissProt Accessions	Q96QS3	Gene names	ARX
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

GSCL_HUMAN
NC score	0.059143 (rank : 62)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	130	Target Neighborhood Hits	343	Shared Neighborhood Hits	46
SwissProt Accessions	O15499	Gene names	GSCL
Domain Architecture
Description	Homeobox protein goosecoid-like (GSC-2).

ARX_MOUSE
NC score	0.059018 (rank : 63)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	130	Target Neighborhood Hits	398	Shared Neighborhood Hits	48
SwissProt Accessions	O35085, Q9QYT4	Gene names	Arx
Domain Architecture
Description	Homeobox protein ARX (Aristaless-related homeobox).

PRRXL_MOUSE
NC score	0.058682 (rank : 64)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	130	Target Neighborhood Hits	350	Shared Neighborhood Hits	47
SwissProt Accessions	Q8BYH0, Q8K3F8	Gene names	Prrxl1, Drg11
Domain Architecture	No domain graphic available
Description	Paired-related homeobox protein-like 1 (Dorsal root ganglion 11) (Homeobox protein DRG11).

GSC_MOUSE
NC score	0.058028 (rank : 65)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	130	Target Neighborhood Hits	368	Shared Neighborhood Hits	48
SwissProt Accessions	Q02591	Gene names	Gsc
Domain Architecture
Description	Homeobox protein goosecoid.

GSC_HUMAN
NC score	0.057884 (rank : 66)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	130	Target Neighborhood Hits	369	Shared Neighborhood Hits	48
SwissProt Accessions	P56915, Q86YR1	Gene names	GSC
Domain Architecture	No domain graphic available
Description	Homeobox protein goosecoid.

PRRX2_MOUSE
NC score	0.057059 (rank : 67)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	130	Target Neighborhood Hits	351	Shared Neighborhood Hits	45
SwissProt Accessions	Q06348, Q61651	Gene names	Prrx2, Prx2, S8
Domain Architecture
Description	Paired mesoderm homeobox protein 2 (PRX-2) (Homeobox protein S8).

DUX1_HUMAN
NC score	0.057000 (rank : 68)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	130	Target Neighborhood Hits	330	Shared Neighborhood Hits	46
SwissProt Accessions	O43812	Gene names	DUX1
Domain Architecture	No domain graphic available
Description	Double homeobox protein 1.

DUX5_HUMAN
NC score	0.056822 (rank : 69)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	130	Target Neighborhood Hits	330	Shared Neighborhood Hits	46
SwissProt Accessions	Q96PT3	Gene names	DUX5
Domain Architecture	No domain graphic available
Description	Double homeobox protein 5.

PRRX2_HUMAN
NC score	0.056741 (rank : 70)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	130	Target Neighborhood Hits	348	Shared Neighborhood Hits	45
SwissProt Accessions	Q99811, Q9UIB3	Gene names	PRRX2, PMX2, PRX2
Domain Architecture
Description	Paired mesoderm homeobox protein 2 (PRX-2) (Paired-related homeobox protein 2).

CART1_HUMAN
NC score	0.055628 (rank : 71)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	130	Target Neighborhood Hits	348	Shared Neighborhood Hits	43
SwissProt Accessions	Q15699, Q546C8, Q96FH4	Gene names	CART1
Domain Architecture
Description	Cartilage homeoprotein 1 (CART-1).

CART1_MOUSE
NC score	0.055533 (rank : 72)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	130	Target Neighborhood Hits	344	Shared Neighborhood Hits	43
SwissProt Accessions	Q8C8B0, Q8C370	Gene names	Cart1
Domain Architecture	No domain graphic available
Description	Cartilage homeoprotein 1 (CART-1).

PAX3_HUMAN
NC score	0.055390 (rank : 73)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	130	Target Neighborhood Hits	513	Shared Neighborhood Hits	55
SwissProt Accessions	P23760, Q16448	Gene names	PAX3, HUP2
Domain Architecture
Description	Paired box protein Pax-3 (HUP2).

DUX4_HUMAN
NC score	0.055363 (rank : 74)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	130	Target Neighborhood Hits	403	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UBX2	Gene names	DUX4, DUX10
Domain Architecture	No domain graphic available
Description	Double homeobox protein 4 (Double homeobox protein 10) (Double homeobox protein 4/10).

PRRX1_MOUSE
NC score	0.055326 (rank : 75)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	130	Target Neighborhood Hits	346	Shared Neighborhood Hits	45
SwissProt Accessions	P63013, P43271, Q02810	Gene names	Prrx1, Pmx, Pmx1
Domain Architecture	No domain graphic available
Description	Paired mesoderm homeobox protein 1 (PRX-1) (Paired-related homeobox protein 1) (Homeobox protein mHox) (Homeobox protein K-2).

PRRX1_HUMAN
NC score	0.055303 (rank : 76)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	130	Target Neighborhood Hits	347	Shared Neighborhood Hits	45
SwissProt Accessions	P54821, O60807	Gene names	PRRX1, PMX1
Domain Architecture
Description	Paired mesoderm homeobox protein 1 (PRX-1) (Paired-related homeobox protein 1) (Homeobox protein PHOX1).

CRX_MOUSE
NC score	0.055184 (rank : 77)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	130	Target Neighborhood Hits	359	Shared Neighborhood Hits	48
SwissProt Accessions	O54751	Gene names	Crx
Domain Architecture
Description	Cone-rod homeobox protein.

PAX3_MOUSE
NC score	0.055163 (rank : 78)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	130	Target Neighborhood Hits	478	Shared Neighborhood Hits	54
SwissProt Accessions	P24610, Q3UFQ9, Q8BRE7, Q9CXI6	Gene names	Pax3, Pax-3
Domain Architecture
Description	Paired box protein Pax-3.

CRX_HUMAN
NC score	0.055111 (rank : 79)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	130	Target Neighborhood Hits	360	Shared Neighborhood Hits	49
SwissProt Accessions	O43186	Gene names	CRX, CORD2
Domain Architecture
Description	Cone-rod homeobox protein.

OTP_MOUSE
NC score	0.055081 (rank : 80)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	130	Target Neighborhood Hits	387	Shared Neighborhood Hits	47
SwissProt Accessions	O09113	Gene names	Otp
Domain Architecture
Description	Homeobox protein orthopedia.

LMX1A_MOUSE
NC score	0.055047 (rank : 81)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	130	Target Neighborhood Hits	405	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JKU8	Gene names	Lmx1a
Domain Architecture
Description	LIM homeobox transcription factor 1 alpha (LIM/homeobox protein LMX1A) (LIM-homeobox protein 1.1) (LMX-1.1).

DUX3_HUMAN
NC score	0.054952 (rank : 82)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	130	Target Neighborhood Hits	312	Shared Neighborhood Hits	46
SwissProt Accessions	Q96PT4, Q9UND2	Gene names	DUX3
Domain Architecture	No domain graphic available
Description	Putative double homeobox protein 3.

PAX7_HUMAN
NC score	0.054845 (rank : 83)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	130	Target Neighborhood Hits	456	Shared Neighborhood Hits	53
SwissProt Accessions	P23759	Gene names	PAX7, HUP1
Domain Architecture
Description	Paired box protein Pax-7 (HUP1).

LHX3_HUMAN
NC score	0.054836 (rank : 84)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	130	Target Neighborhood Hits	474	Shared Neighborhood Hits	51
SwissProt Accessions	Q9UBR4, Q9NZB5, Q9P0I8, Q9P0I9	Gene names	LHX3
Domain Architecture
Description	LIM/homeobox protein Lhx3.

LHX3_MOUSE
NC score	0.054708 (rank : 85)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	130	Target Neighborhood Hits	451	Shared Neighborhood Hits	51
SwissProt Accessions	P50481, Q61800, Q61801	Gene names	Lhx3, Lim-3, Lim3, Plim
Domain Architecture
Description	LIM/homeobox protein Lhx3 (Homeobox protein LIM-3) (Homeobox protein P-LIM) (LIM homeobox protein 3).

PAX7_MOUSE
NC score	0.054604 (rank : 86)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	130	Target Neighborhood Hits	422	Shared Neighborhood Hits	51
SwissProt Accessions	P47239, Q9ES16	Gene names	Pax7, Pax-7
Domain Architecture	No domain graphic available
Description	Paired box protein Pax-7.

ZHX1_HUMAN
NC score	0.054311 (rank : 87)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	130	Target Neighborhood Hits	307	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UKY1, Q8IWD8	Gene names	ZHX1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

ZHX2_HUMAN
NC score	0.054161 (rank : 88)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	130	Target Neighborhood Hits	347	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y6X8	Gene names	ZHX2, AFR1, KIAA0854, RAF
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

ZHX1_MOUSE
NC score	0.053976 (rank : 89)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	130	Target Neighborhood Hits	334	Shared Neighborhood Hits	47
SwissProt Accessions	P70121, Q8BQ68, Q8C6T4, Q8CJG3	Gene names	Zhx1
Domain Architecture
Description	Zinc fingers and homeoboxes protein 1.

LHX4_HUMAN
NC score	0.053843 (rank : 90)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	130	Target Neighborhood Hits	455	Shared Neighborhood Hits	49
SwissProt Accessions	Q969G2, Q8NHE0, Q8TCJ1, Q8WWX2, Q969W2	Gene names	LHX4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

PHX2A_HUMAN
NC score	0.053691 (rank : 91)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	130	Target Neighborhood Hits	345	Shared Neighborhood Hits	45
SwissProt Accessions	O14813, Q8IVZ2	Gene names	PHOX2A, ARIX, PMX2A
Domain Architecture
Description	Paired mesoderm homeobox protein 2A (Paired-like homeobox 2A) (Aristaless homeobox protein homolog) (ARIX1 homeodomain protein).

PHX2A_MOUSE
NC score	0.053690 (rank : 92)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	130	Target Neighborhood Hits	338	Shared Neighborhood Hits	45
SwissProt Accessions	Q62066	Gene names	Phox2a, Arix, Phox2, Pmx2, Pmx2a
Domain Architecture
Description	Paired mesoderm homeobox protein 2A (Paired-like homeobox 2A) (PHOX2A homeodomain protein) (Aristaless homeobox protein homolog).

LHX4_MOUSE
NC score	0.053575 (rank : 93)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	130	Target Neighborhood Hits	457	Shared Neighborhood Hits	49
SwissProt Accessions	P53776, O08916, Q9R280	Gene names	Lhx4, Gsh-4, Gsh4
Domain Architecture
Description	LIM/homeobox protein Lhx4.

OTX2_MOUSE
NC score	0.053360 (rank : 94)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	130	Target Neighborhood Hits	345	Shared Neighborhood Hits	45
SwissProt Accessions	P80206	Gene names	Otx2, Otx-2
Domain Architecture
Description	Homeobox protein OTX2.

OTX2_HUMAN
NC score	0.053325 (rank : 95)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	130	Target Neighborhood Hits	341	Shared Neighborhood Hits	44
SwissProt Accessions	P32243, Q6GTV3, Q9HAW3, Q9P2R1	Gene names	OTX2
Domain Architecture
Description	Homeobox protein OTX2.

PHX2B_HUMAN
NC score	0.053007 (rank : 96)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	130	Target Neighborhood Hits	407	Shared Neighborhood Hits	47
SwissProt Accessions	Q99453, Q6PJD9	Gene names	PHOX2B, PMX2B
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

PHX2B_MOUSE
NC score	0.053007 (rank : 97)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	130	Target Neighborhood Hits	407	Shared Neighborhood Hits	47
SwissProt Accessions	O35690	Gene names	Phox2b, Pmx2b
Domain Architecture
Description	Paired mesoderm homeobox protein 2B (Paired-like homeobox 2B) (PHOX2B homeodomain protein) (Neuroblastoma Phox) (NBPhox).

PITX3_MOUSE
NC score	0.052833 (rank : 98)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	130	Target Neighborhood Hits	380	Shared Neighborhood Hits	49
SwissProt Accessions	O35160	Gene names	Pitx3
Domain Architecture
Description	Pituitary homeobox 3 (Homeobox protein PITX3).

PITX3_HUMAN
NC score	0.052832 (rank : 99)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	130	Target Neighborhood Hits	366	Shared Neighborhood Hits	47
SwissProt Accessions	O75364	Gene names	PITX3, PTX3
Domain Architecture
Description	Pituitary homeobox 3 (Homeobox protein PITX3).

PITX2_HUMAN
NC score	0.052431 (rank : 100)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	130	Target Neighborhood Hits	381	Shared Neighborhood Hits	46
SwissProt Accessions	Q99697, O60578, O60579, O60580, Q9BY17	Gene names	PITX2, ARP1, RGS, RIEG, RIEG1
Domain Architecture
Description	Pituitary homeobox 2 (RIEG bicoid-related homeobox transcription factor) (Solurshin) (ALL1-responsive protein ARP1).

PITX2_MOUSE
NC score	0.052083 (rank : 101)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	130	Target Neighborhood Hits	383	Shared Neighborhood Hits	46
SwissProt Accessions	P97474, O08646, O70336, P97933, Q9JLA0, Q9QXB8, Q9R1V9, Q9Z141	Gene names	Pitx2, Arp1, Brx1, Otlx2, Ptx2, Rgs
Domain Architecture
Description	Pituitary homeobox 2 (Orthodenticle-like homeobox 2) (Solurshin) (ALL1-responsive protein ARP1) (BRX1 homeoprotein) (Paired-like homeodomain transcription factor Munc 30).

PITX1_HUMAN
NC score	0.051849 (rank : 102)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	130	Target Neighborhood Hits	353	Shared Neighborhood Hits	45
SwissProt Accessions	P78337, O14677, O60425, Q9BTI5	Gene names	PITX1, BFT, PTX1
Domain Architecture
Description	Pituitary homeobox 1 (Hindlimb expressed homeobox protein backfoot).

LMX1B_HUMAN
NC score	0.051842 (rank : 103)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	130	Target Neighborhood Hits	404	Shared Neighborhood Hits	46
SwissProt Accessions	O60663, O75463	Gene names	LMX1B
Domain Architecture
Description	LIM homeobox transcription factor 1 beta (LIM/homeobox protein LMX1B) (LIM-homeobox protein 1.2) (LMX-1.2).

LMX1B_MOUSE
NC score	0.051726 (rank : 104)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	130	Target Neighborhood Hits	394	Shared Neighborhood Hits	46
SwissProt Accessions	O88609	Gene names	Lmx1b
Domain Architecture
Description	LIM homeobox transcription factor 1 beta (LIM/homeobox protein LMX1B) (LIM-homeobox protein 1.2) (LMX-1.2).

PEPP2_HUMAN
NC score	0.051539 (rank : 105)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	130	Target Neighborhood Hits	316	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BQY4, Q9BR00	Gene names	PEPP2, THG1
Domain Architecture
Description	Paired-like homeobox protein PEPP-2 (Testis homeobox gene 1).

PITX1_MOUSE
NC score	0.051505 (rank : 106)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	130	Target Neighborhood Hits	362	Shared Neighborhood Hits	45
SwissProt Accessions	P70314, O54742, P70427	Gene names	Pitx1, Bft, Potx, Ptx1
Domain Architecture
Description	Pituitary homeobox 1 (Homeobox protein P-OTX) (Pituitary OTX-related factor) (Hindlimb expressed homeobox protein backfoot) (Ptx1).

PO6F2_HUMAN
NC score	0.051048 (rank : 107)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	130	Target Neighborhood Hits	618	Shared Neighborhood Hits	61
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

GSCR2_HUMAN
NC score	0.046762 (rank : 108)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	130	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NZM5, Q9BTC6, Q9HAX6, Q9NPP1, Q9NPR4, Q9UFI2	Gene names	GLTSCR2
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 2 protein (p60).

PO2F1_MOUSE
NC score	0.046026 (rank : 109)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	130	Target Neighborhood Hits	408	Shared Neighborhood Hits	52
SwissProt Accessions	P25425, Q61994, Q63891, Q6Y681, Q7TSD0, Q8BT04, Q8K570, Q99JH0, Q9WTZ4, Q9WTZ5, Q9WTZ6	Gene names	Pou2f1, Oct-1, Otf-1, Otf1
Domain Architecture
Description	POU domain, class 2, transcription factor 1 (Octamer-binding transcription factor 1) (Oct-1) (OTF-1) (NF-A1).

PCQAP_HUMAN
NC score	0.045508 (rank : 110)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	130	Target Neighborhood Hits	549	Shared Neighborhood Hits	17
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

NCOA6_HUMAN
NC score	0.042960 (rank : 111)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	130	Target Neighborhood Hits	1202	Shared Neighborhood Hits	47
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

WIRE_MOUSE
NC score	0.039533 (rank : 112)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	130	Target Neighborhood Hits	310	Shared Neighborhood Hits	21
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

UBQL4_HUMAN
NC score	0.039349 (rank : 113)	θ value	0.62314 (rank : 37)
Query Neighborhood Hits	130	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NRR5, Q9BR98, Q9UHX4	Gene names	UBQLN4, C1orf6, UBIN
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

PCQAP_MOUSE
NC score	0.039332 (rank : 114)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	130	Target Neighborhood Hits	506	Shared Neighborhood Hits	21
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

SAMH1_MOUSE
NC score	0.039284 (rank : 115)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	130	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q60710, Q91VK8	Gene names	Samhd1, Mg11
Domain Architecture
Description	SAM domain and HD domain-containing protein 1 (Interferon-gamma- inducible protein Mg11).

NCOA6_MOUSE
NC score	0.037845 (rank : 116)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	130	Target Neighborhood Hits	1076	Shared Neighborhood Hits	43
SwissProt Accessions	Q9JL19, Q9JLT9	Gene names	Ncoa6, Aib3, Prip, Rap250, Trbp
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC) (Thyroid hormone receptor-binding protein).

MA1B1_HUMAN
NC score	0.037711 (rank : 117)	θ value	0.365318 (rank : 30)
Query Neighborhood Hits	130	Target Neighborhood Hits	125	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

FYB_HUMAN
NC score	0.037411 (rank : 118)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	130	Target Neighborhood Hits	379	Shared Neighborhood Hits	16
SwissProt Accessions	O15117, O00359	Gene names	FYB, SLAP130
Domain Architecture
Description	FYN-binding protein (FYN-T-binding protein) (FYB-120/130) (p120/p130) (SLP-76-associated phosphoprotein) (SLAP-130).

DVL2_MOUSE
NC score	0.036386 (rank : 119)	θ value	0.163984 (rank : 18)
Query Neighborhood Hits	130	Target Neighborhood Hits	233	Shared Neighborhood Hits	7
SwissProt Accessions	Q60838	Gene names	Dvl2
Domain Architecture
Description	Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2).

UBQL4_MOUSE
NC score	0.035475 (rank : 120)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	130	Target Neighborhood Hits	99	Shared Neighborhood Hits	8
SwissProt Accessions	Q99NB8, Q8BP88	Gene names	Ubqln4, Ubin
Domain Architecture
Description	Ubiquilin-4 (Ataxin-1 ubiquitin-like-interacting protein A1U).

ARI1A_HUMAN
NC score	0.034710 (rank : 121)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	130	Target Neighborhood Hits	787	Shared Neighborhood Hits	32
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

AMOL2_HUMAN
NC score	0.034280 (rank : 122)	θ value	0.47712 (rank : 32)
Query Neighborhood Hits	130	Target Neighborhood Hits	603	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

WIRE_HUMAN
NC score	0.033797 (rank : 123)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	130	Target Neighborhood Hits	329	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

TBC10_MOUSE
NC score	0.032028 (rank : 124)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	130	Target Neighborhood Hits	94	Shared Neighborhood Hits	9
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

NPBL_MOUSE
NC score	0.031727 (rank : 125)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	130	Target Neighborhood Hits	1041	Shared Neighborhood Hits	29
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

CI079_HUMAN
NC score	0.031216 (rank : 126)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	130	Target Neighborhood Hits	288	Shared Neighborhood Hits	16
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

MLL3_HUMAN
NC score	0.030596 (rank : 127)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	130	Target Neighborhood Hits	1644	Shared Neighborhood Hits	53
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MKL1_MOUSE
NC score	0.029523 (rank : 128)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	130	Target Neighborhood Hits	667	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

BAG3_MOUSE
NC score	0.029123 (rank : 129)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	130	Target Neighborhood Hits	513	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

MLL4_HUMAN
NC score	0.027640 (rank : 130)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	130	Target Neighborhood Hits	722	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

EP400_HUMAN
NC score	0.026516 (rank : 131)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	130	Target Neighborhood Hits	556	Shared Neighborhood Hits	21
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

PHF14_MOUSE
NC score	0.026117 (rank : 132)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	130	Target Neighborhood Hits	342	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

IZUM1_MOUSE
NC score	0.025049 (rank : 133)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	130	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D9J7	Gene names	Izumo1
Domain Architecture	No domain graphic available
Description	Izumo sperm-egg fusion protein 1 precursor (Sperm-specific protein izumo).

MLL2_HUMAN
NC score	0.025001 (rank : 134)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	130	Target Neighborhood Hits	1788	Shared Neighborhood Hits	46
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

EP400_MOUSE
NC score	0.024996 (rank : 135)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	130	Target Neighborhood Hits	592	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

NIPBL_HUMAN
NC score	0.024784 (rank : 136)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	130	Target Neighborhood Hits	1311	Shared Neighborhood Hits	29
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

COG8_MOUSE
NC score	0.023955 (rank : 137)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	130	Target Neighborhood Hits	147	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JJA2	Gene names	Cog8
Domain Architecture
Description	Conserved oligomeric Golgi complex component 8.

NFAT5_HUMAN
NC score	0.023147 (rank : 138)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	130	Target Neighborhood Hits	217	Shared Neighborhood Hits	20
SwissProt Accessions	O94916, O95693, Q9UN18	Gene names	NFAT5, KIAA0827, TONEBP
Domain Architecture
Description	Nuclear factor of activated T-cells 5 (T-cell transcription factor NFAT5) (NF-AT5) (Tonicity-responsive enhancer-binding protein) (TonE- binding protein) (TonEBP).

MBD6_HUMAN
NC score	0.022991 (rank : 139)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	130	Target Neighborhood Hits	349	Shared Neighborhood Hits	21
SwissProt Accessions	Q96DN6, Q8N3M0, Q8NA81, Q96Q00	Gene names	MBD6, KIAA1887
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 6 (Methyl-CpG-binding protein MBD6).

PRR3_MOUSE
NC score	0.022660 (rank : 140)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	130	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q811B5, Q91YI5	Gene names	Prr3, Cat56
Domain Architecture	No domain graphic available
Description	Proline-rich protein 3 (MHC class I region proline-rich protein CAT56).

DMRTC_MOUSE
NC score	0.022534 (rank : 141)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	130	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D9R7, Q2PMY0, Q9D5U3	Gene names	Dmrtc1, Dmrt8.1
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C1 (Doublesex- and mab-3-related transcription factor 8.1).

HOOK2_MOUSE
NC score	0.022123 (rank : 142)	θ value	1.38821 (rank : 52)
Query Neighborhood Hits	130	Target Neighborhood Hits	736	Shared Neighborhood Hits	18
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

US6NL_MOUSE
NC score	0.022084 (rank : 143)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	130	Target Neighborhood Hits	157	Shared Neighborhood Hits	6
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

PI3R5_HUMAN
NC score	0.021547 (rank : 144)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	130	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q8WYR1, Q5G936, Q5G938, Q5G939, Q8IZ23, Q9Y2Y2	Gene names	PIK3R5
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 5 (PI3-kinase regulatory subunit 5) (PI3-kinase p101 subunit) (PtdIns-3-kinase p101) (p101- PI3K) (Phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit) (PtdIns-3-kinase regulatory subunit) (Protein FOAP-2).

HAP1_MOUSE
NC score	0.021183 (rank : 145)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	130	Target Neighborhood Hits	388	Shared Neighborhood Hits	14
SwissProt Accessions	O35668, O35636	Gene names	Hap1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1).

FOXJ3_MOUSE
NC score	0.020259 (rank : 146)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	130	Target Neighborhood Hits	190	Shared Neighborhood Hits	10
SwissProt Accessions	Q8BUR3, Q3UTD8	Gene names	Foxj3, Kiaa1041
Domain Architecture
Description	Forkhead box protein J3.

MAML3_HUMAN
NC score	0.019235 (rank : 147)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	130	Target Neighborhood Hits	323	Shared Neighborhood Hits	16
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

SRC8_MOUSE
NC score	0.017999 (rank : 148)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	130	Target Neighborhood Hits	292	Shared Neighborhood Hits	9
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

MINT_HUMAN
NC score	0.017746 (rank : 149)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	130	Target Neighborhood Hits	1291	Shared Neighborhood Hits	35
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

OXRP_HUMAN
NC score	0.017701 (rank : 150)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	130	Target Neighborhood Hits	544	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

RPGF1_HUMAN
NC score	0.016805 (rank : 151)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	130	Target Neighborhood Hits	262	Shared Neighborhood Hits	10
SwissProt Accessions	Q13905	Gene names	RAPGEF1, GRF2
Domain Architecture
Description	Rap guanine nucleotide exchange factor 1 (Guanine nucleotide-releasing factor 2) (C3G protein) (CRK SH3-binding GNRP).

TSH1_HUMAN
NC score	0.015775 (rank : 152)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	130	Target Neighborhood Hits	558	Shared Neighborhood Hits	11
SwissProt Accessions	Q6ZSZ6, O60534, Q4LE29, Q53EU4	Gene names	TSHZ1, SDCCAG33, TSH1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3) (Antigen NY-CO-33).

EEA1_HUMAN
NC score	0.015509 (rank : 153)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	130	Target Neighborhood Hits	1796	Shared Neighborhood Hits	28
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

KPBB_HUMAN
NC score	0.015400 (rank : 154)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	130	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q93100, Q8N4T5	Gene names	PHKB
Domain Architecture
Description	Phosphorylase b kinase regulatory subunit beta (Phosphorylase kinase subunit beta).

DNMBP_MOUSE
NC score	0.015085 (rank : 155)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	130	Target Neighborhood Hits	435	Shared Neighborhood Hits	10
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

CRK_HUMAN
NC score	0.014267 (rank : 156)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	130	Target Neighborhood Hits	308	Shared Neighborhood Hits	7
SwissProt Accessions	P46108	Gene names	CRK
Domain Architecture
Description	Proto-oncogene C-crk (P38) (Adapter molecule crk).

NEB1_HUMAN
NC score	0.014044 (rank : 157)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	130	Target Neighborhood Hits	829	Shared Neighborhood Hits	17
SwissProt Accessions	Q9ULJ8, O76059, Q9NXT2	Gene names	PPP1R9A, KIAA1222
Domain Architecture	No domain graphic available
Description	Neurabin-1 (Neurabin-I) (Neural tissue-specific F-actin-binding protein I) (Protein phosphatase 1 regulatory subunit 9A).

EEA1_MOUSE
NC score	0.013721 (rank : 158)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	130	Target Neighborhood Hits	1637	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

SYNJ1_HUMAN
NC score	0.013135 (rank : 159)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	130	Target Neighborhood Hits	498	Shared Neighborhood Hits	30
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

AKAP6_HUMAN
NC score	0.012572 (rank : 160)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	130	Target Neighborhood Hits	263	Shared Neighborhood Hits	9
SwissProt Accessions	Q13023, O15028	Gene names	AKAP6, AKAP100, KIAA0311
Domain Architecture
Description	A-kinase anchor protein 6 (Protein kinase A-anchoring protein 6) (PRKA6) (A-kinase anchor protein 100 kDa) (AKAP 100) (mAKAP).

KIF11_HUMAN
NC score	0.011939 (rank : 161)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	130	Target Neighborhood Hits	583	Shared Neighborhood Hits	11
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

N4BP3_HUMAN
NC score	0.011711 (rank : 162)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	130	Target Neighborhood Hits	156	Shared Neighborhood Hits	5
SwissProt Accessions	O15049, Q7Z6I3	Gene names	N4BP3, KIAA0341
Domain Architecture
Description	NEDD4-binding protein 3 (N4BP3).

ASPP2_HUMAN
NC score	0.011427 (rank : 163)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	130	Target Neighborhood Hits	1156	Shared Neighborhood Hits	25
SwissProt Accessions	Q13625, Q12892, Q86X75, Q96KQ3	Gene names	TP53BP2, ASPP2, BBP
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (p53-binding protein 2) (p53BP2) (53BP2) (Bcl2-binding protein) (Bbp) (NY-REN-51 antigen).

3BP1_HUMAN
NC score	0.011258 (rank : 164)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	130	Target Neighborhood Hits	376	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

DLG5_HUMAN
NC score	0.010122 (rank : 165)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	130	Target Neighborhood Hits	1088	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

ANDR_MOUSE
NC score	0.008445 (rank : 166)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	130	Target Neighborhood Hits	133	Shared Neighborhood Hits	8
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

GAK12_HUMAN
NC score	0.008309 (rank : 167)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	130	Target Neighborhood Hits	374	Shared Neighborhood Hits	24
SwissProt Accessions	P63130, Q9UKI0	Gene names
Domain Architecture	No domain graphic available
Description	HERV-K_1q22 provirus ancestral Gag polyprotein (Gag polyprotein) (HERV-K102 Gag protein) (HERV-K(III) Gag protein) [Contains: Matrix protein; Capsid protein; Nucleocapsid protein].

CO5A3_HUMAN
NC score	0.007951 (rank : 168)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	130	Target Neighborhood Hits	433	Shared Neighborhood Hits	13
SwissProt Accessions	P25940, Q9NZQ6	Gene names	COL5A3
Domain Architecture
Description	Collagen alpha-3(V) chain precursor.

USP9X_HUMAN
NC score	0.007611 (rank : 169)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	130	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	Q93008, O75550, Q8WWT3, Q8WX12	Gene names	USP9X, DFFRX, USP9
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.1.2.15) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific-processing protease FAF-X) (Deubiquitinating enzyme FAF-X) (Fat facets protein-related, X- linked) (Ubiquitin-specific protease 9, X chromosome).

COE4_HUMAN
NC score	0.007187 (rank : 170)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	130	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BQW3, Q5JY53, Q9NUB6, Q9P2A6	Gene names	EBF4, COE4, KIAA1442
Domain Architecture
Description	Transcription factor COE4 (Early B-cell factor 4) (EBF-4) (Olf-1/EBF- like 4) (OE-4) (O/E-4).

TNKS1_HUMAN
NC score	0.006333 (rank : 171)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	130	Target Neighborhood Hits	477	Shared Neighborhood Hits	8
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

CAC1G_HUMAN
NC score	0.005517 (rank : 172)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	130	Target Neighborhood Hits	587	Shared Neighborhood Hits	20
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

BOC_HUMAN
NC score	0.005240 (rank : 173)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	130	Target Neighborhood Hits	543	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BWV1, Q6UXJ5, Q8N2P7, Q8NF26	Gene names	BOC
Domain Architecture	No domain graphic available
Description	Brother of CDO precursor (Protein BOC).

SALL3_HUMAN
NC score	0.005138 (rank : 174)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	130	Target Neighborhood Hits	1066	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BXA9, Q9UGH1	Gene names	SALL3
Domain Architecture	No domain graphic available
Description	Sal-like protein 3 (Zinc finger protein SALL3) (hSALL3).

ZN142_HUMAN
NC score	0.004094 (rank : 175)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	130	Target Neighborhood Hits	1007	Shared Neighborhood Hits	24
SwissProt Accessions	P52746, Q92510	Gene names	ZNF142, KIAA0236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 142 (HA4654).

TENX_HUMAN
NC score	0.004022 (rank : 176)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	130	Target Neighborhood Hits	789	Shared Neighborhood Hits	11
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

ZN516_MOUSE
NC score	0.003373 (rank : 177)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	130	Target Neighborhood Hits	1197	Shared Neighborhood Hits	32
SwissProt Accessions	Q7TSH3	Gene names	Znf516, Kiaa0222, Zfp516
Domain Architecture
Description	Zinc finger protein 516.

SN1L2_MOUSE
NC score	0.001883 (rank : 178)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	130	Target Neighborhood Hits	944	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).

ZN342_HUMAN
NC score	0.001549 (rank : 179)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	130	Target Neighborhood Hits	705	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WUU4	Gene names	ZNF342
Domain Architecture	No domain graphic available
Description	Zinc finger protein 342.

KSR1_HUMAN
NC score	0.000744 (rank : 180)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	130	Target Neighborhood Hits	867	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).