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Network neighborhood for query Sequence : TBC10_MOUSE

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TBC10_MOUSE
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TBC10_HUMAN
θ value	0 (rank : 1)	NC score	0.988274 (rank : 2)
Query Neighborhood Hits	94	Target Neighborhood Hits	64	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXI6, O76053, Q543A2	Gene names	TBC1D10A, EPI64, TBC1D10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

TBC10_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	94	Target Neighborhood Hits	94	Shared Neighborhood Hits	94
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

TBCD8_MOUSE
θ value	5.77852e-31 (rank : 3)	NC score	0.756369 (rank : 6)
Query Neighborhood Hits	94	Target Neighborhood Hits	64	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1A9	Gene names	Tbc1d8, Hblp1, Vrp
Domain Architecture
Description	TBC1 domain family member 8 (Vascular Rab-GAP/TBC-containing protein) (BUB2-like protein 1).

US6NL_MOUSE
θ value	9.8567e-31 (rank : 4)	NC score	0.805776 (rank : 3)
Query Neighborhood Hits	94	Target Neighborhood Hits	157	Shared Neighborhood Hits	34
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

US6NL_HUMAN
θ value	4.89182e-30 (rank : 5)	NC score	0.798564 (rank : 4)
Query Neighborhood Hits	94	Target Neighborhood Hits	201	Shared Neighborhood Hits	37
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

TBCD8_HUMAN
θ value	1.08979e-29 (rank : 6)	NC score	0.748758 (rank : 7)
Query Neighborhood Hits	94	Target Neighborhood Hits	65	Shared Neighborhood Hits	22
SwissProt Accessions	O95759, Q9UQ32	Gene names	TBC1D8, VRP
Domain Architecture
Description	TBC1 domain family member 8 (Vascular Rab-GAP/TBC-containing protein) (AD 3).

TBCD4_MOUSE
θ value	1.02001e-27 (rank : 7)	NC score	0.716757 (rank : 11)
Query Neighborhood Hits	94	Target Neighborhood Hits	276	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TBCD4_HUMAN
θ value	1.47289e-26 (rank : 8)	NC score	0.704490 (rank : 14)
Query Neighborhood Hits	94	Target Neighborhood Hits	357	Shared Neighborhood Hits	27
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TBCD1_HUMAN
θ value	9.54697e-26 (rank : 9)	NC score	0.739316 (rank : 9)
Query Neighborhood Hits	94	Target Neighborhood Hits	276	Shared Neighborhood Hits	32
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

TBCD1_MOUSE
θ value	6.18819e-25 (rank : 10)	NC score	0.731423 (rank : 10)
Query Neighborhood Hits	94	Target Neighborhood Hits	241	Shared Neighborhood Hits	30
SwissProt Accessions	Q60949, Q80TJ9, Q923F8	Gene names	Tbc1d1, Kiaa1108, Tbc1
Domain Architecture
Description	TBC1 domain family member 1.

TBCD2_HUMAN
θ value	5.23862e-24 (rank : 11)	NC score	0.681383 (rank : 15)
Query Neighborhood Hits	94	Target Neighborhood Hits	419	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

UBP6_HUMAN
θ value	3.39556e-23 (rank : 12)	NC score	0.447868 (rank : 21)
Query Neighborhood Hits	94	Target Neighborhood Hits	188	Shared Neighborhood Hits	25
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

TBCD3_HUMAN
θ value	2.20094e-22 (rank : 13)	NC score	0.756895 (rank : 5)
Query Neighborhood Hits	94	Target Neighborhood Hits	51	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

TBC12_HUMAN
θ value	2.27762e-19 (rank : 14)	NC score	0.743441 (rank : 8)
Query Neighborhood Hits	94	Target Neighborhood Hits	80	Shared Neighborhood Hits	29
SwissProt Accessions	O60347, Q5VYA6, Q8WX26, Q8WX59, Q9UG83	Gene names	TBC1D12, KIAA0608
Domain Architecture
Description	TBC1 domain family member 12.

TBC14_HUMAN
θ value	5.07402e-19 (rank : 15)	NC score	0.715431 (rank : 12)
Query Neighborhood Hits	94	Target Neighborhood Hits	124	Shared Neighborhood Hits	30
SwissProt Accessions	Q9P2M4, Q8IW15	Gene names	TBC1D14, KIAA1322
Domain Architecture
Description	TBC1 domain family member 14.

TBC14_MOUSE
θ value	1.92812e-18 (rank : 16)	NC score	0.710303 (rank : 13)
Query Neighborhood Hits	94	Target Neighborhood Hits	135	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CGA2, Q8CHA5	Gene names	Tbc1d14, D5Ertd110e, Kiaa1322
Domain Architecture
Description	TBC1 domain family member 14.

TBC15_MOUSE
θ value	2.13673e-09 (rank : 17)	NC score	0.476731 (rank : 17)
Query Neighborhood Hits	94	Target Neighborhood Hits	40	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CXF4, Q3UI41	Gene names	Tbc1d15
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 15.

TBC17_HUMAN
θ value	2.79066e-09 (rank : 18)	NC score	0.466730 (rank : 19)
Query Neighborhood Hits	94	Target Neighborhood Hits	60	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HA65	Gene names	TBC1D17
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 17.

TBC15_HUMAN
θ value	1.38499e-08 (rank : 19)	NC score	0.468996 (rank : 18)
Query Neighborhood Hits	94	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TC07	Gene names	TBC1D15
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 15.

TBC16_HUMAN
θ value	8.97725e-08 (rank : 20)	NC score	0.571164 (rank : 16)
Query Neighborhood Hits	94	Target Neighborhood Hits	55	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TBP0	Gene names	TBC1D16
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 16.

TBC17_MOUSE
θ value	1.53129e-07 (rank : 21)	NC score	0.466480 (rank : 20)
Query Neighborhood Hits	94	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BYH7	Gene names	Tbc1d17
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 17.

TBCD5_HUMAN
θ value	0.000461057 (rank : 22)	NC score	0.293398 (rank : 26)
Query Neighborhood Hits	94	Target Neighborhood Hits	70	Shared Neighborhood Hits	23
SwissProt Accessions	Q92609	Gene names	TBC1D5, KIAA0210
Domain Architecture
Description	TBC1 domain family member 5.

TB22A_HUMAN
θ value	0.00102713 (rank : 23)	NC score	0.340577 (rank : 24)
Query Neighborhood Hits	94	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WUA7, Q5TE47, Q6ZUH2, Q92680, Q9BVD6, Q9UGG0, Q9UGT2, Q9UGU6, Q9UH25, Q9Y4W5	Gene names	TBC1D22A, C22orf4
Domain Architecture
Description	TBC1 domain family member 22A.

TBCD5_MOUSE
θ value	0.00102713 (rank : 24)	NC score	0.274468 (rank : 27)
Query Neighborhood Hits	94	Target Neighborhood Hits	71	Shared Neighborhood Hits	22
SwissProt Accessions	Q80XQ2	Gene names	Tbc1d5
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 5.

TB22B_HUMAN
θ value	0.00134147 (rank : 25)	NC score	0.363734 (rank : 22)
Query Neighborhood Hits	94	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NU19, Q5VUK9, Q7Z6P7, Q9BPV6, Q9BUT5, Q9NXB6	Gene names	TBC1D22B, C6orf197
Domain Architecture
Description	TBC1 domain family member 22B.

TB22A_MOUSE
θ value	0.00228821 (rank : 26)	NC score	0.341428 (rank : 23)
Query Neighborhood Hits	94	Target Neighborhood Hits	42	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R5A6, Q3U268, Q3U3T0, Q8CA49	Gene names	Tbc1d22a, D15Ertd781e
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 22A.

DLG5_HUMAN
θ value	0.0961366 (rank : 27)	NC score	0.019238 (rank : 70)
Query Neighborhood Hits	94	Target Neighborhood Hits	1088	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

CSKI1_HUMAN
θ value	0.21417 (rank : 28)	NC score	0.019428 (rank : 69)
Query Neighborhood Hits	94	Target Neighborhood Hits	997	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

TAF9_HUMAN
θ value	0.21417 (rank : 29)	NC score	0.040202 (rank : 39)
Query Neighborhood Hits	94	Target Neighborhood Hits	41	Shared Neighborhood Hits	7
SwissProt Accessions	Q16594, Q9BTS1	Gene names	TAF9, TAF2G, TAFII31
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32) (STAF31/32).

ATBF1_MOUSE
θ value	0.279714 (rank : 30)	NC score	0.018061 (rank : 74)
Query Neighborhood Hits	94	Target Neighborhood Hits	1841	Shared Neighborhood Hits	29
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

PDLI5_MOUSE
θ value	0.279714 (rank : 31)	NC score	0.015114 (rank : 82)
Query Neighborhood Hits	94	Target Neighborhood Hits	287	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

PRG4_MOUSE
θ value	0.365318 (rank : 32)	NC score	0.030130 (rank : 42)
Query Neighborhood Hits	94	Target Neighborhood Hits	624	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

TBCD7_HUMAN
θ value	0.365318 (rank : 33)	NC score	0.136912 (rank : 30)
Query Neighborhood Hits	94	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P0N9	Gene names	TBC1D7
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 7.

MLL4_HUMAN
θ value	0.47712 (rank : 34)	NC score	0.025347 (rank : 55)
Query Neighborhood Hits	94	Target Neighborhood Hits	722	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

APBA3_HUMAN
θ value	0.813845 (rank : 35)	NC score	0.020979 (rank : 65)
Query Neighborhood Hits	94	Target Neighborhood Hits	201	Shared Neighborhood Hits	6
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

PCLO_MOUSE
θ value	0.813845 (rank : 36)	NC score	0.026578 (rank : 52)
Query Neighborhood Hits	94	Target Neighborhood Hits	2275	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

AFF3_HUMAN
θ value	1.06291 (rank : 37)	NC score	0.022573 (rank : 60)
Query Neighborhood Hits	94	Target Neighborhood Hits	190	Shared Neighborhood Hits	8
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

PRG4_HUMAN
θ value	1.06291 (rank : 38)	NC score	0.027996 (rank : 47)
Query Neighborhood Hits	94	Target Neighborhood Hits	764	Shared Neighborhood Hits	26
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SATB1_HUMAN
θ value	1.06291 (rank : 39)	NC score	0.034335 (rank : 40)
Query Neighborhood Hits	94	Target Neighborhood Hits	130	Shared Neighborhood Hits	8
SwissProt Accessions	Q01826	Gene names	SATB1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

SPEG_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.008150 (rank : 92)
Query Neighborhood Hits	94	Target Neighborhood Hits	1762	Shared Neighborhood Hits	30
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TBCD7_MOUSE
θ value	1.06291 (rank : 41)	NC score	0.137605 (rank : 29)
Query Neighborhood Hits	94	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D0K0, Q3U0V0	Gene names	Tbc1d7
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 7.

TTC15_HUMAN
θ value	1.06291 (rank : 42)	NC score	0.028190 (rank : 46)
Query Neighborhood Hits	94	Target Neighborhood Hits	112	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WVT3, Q8WVW1, Q9Y395	Gene names	TTC15
Domain Architecture
Description	Tetratricopeptide repeat protein 15 (TPR repeat protein 15).

3BP2_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.025726 (rank : 54)
Query Neighborhood Hits	94	Target Neighborhood Hits	296	Shared Neighborhood Hits	12
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

ATBF1_HUMAN
θ value	1.38821 (rank : 44)	NC score	0.015130 (rank : 81)
Query Neighborhood Hits	94	Target Neighborhood Hits	1547	Shared Neighborhood Hits	22
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

G3BP2_MOUSE
θ value	1.38821 (rank : 45)	NC score	0.023576 (rank : 59)
Query Neighborhood Hits	94	Target Neighborhood Hits	258	Shared Neighborhood Hits	7
SwissProt Accessions	P97379, Q9R1B8	Gene names	G3bp2
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

RGS3_HUMAN
θ value	1.38821 (rank : 46)	NC score	0.026573 (rank : 53)
Query Neighborhood Hits	94	Target Neighborhood Hits	1375	Shared Neighborhood Hits	38
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SRRM1_MOUSE
θ value	1.38821 (rank : 47)	NC score	0.044852 (rank : 37)
Query Neighborhood Hits	94	Target Neighborhood Hits	966	Shared Neighborhood Hits	34
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

BPTF_HUMAN
θ value	1.81305 (rank : 48)	NC score	0.016899 (rank : 76)
Query Neighborhood Hits	94	Target Neighborhood Hits	786	Shared Neighborhood Hits	18
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CNOT3_MOUSE
θ value	1.81305 (rank : 49)	NC score	0.026667 (rank : 51)
Query Neighborhood Hits	94	Target Neighborhood Hits	504	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

FA61A_MOUSE
θ value	1.81305 (rank : 50)	NC score	0.023954 (rank : 58)
Query Neighborhood Hits	94	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K2F8, Q9CTG8	Gene names	Fam61a
Domain Architecture	No domain graphic available
Description	Protein FAM61A.

LETM1_MOUSE
θ value	1.81305 (rank : 51)	NC score	0.029051 (rank : 43)
Query Neighborhood Hits	94	Target Neighborhood Hits	240	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

RP1L1_MOUSE
θ value	1.81305 (rank : 52)	NC score	0.021161 (rank : 63)
Query Neighborhood Hits	94	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

SL9A5_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.015296 (rank : 79)
Query Neighborhood Hits	94	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q14940, Q9Y626	Gene names	SLC9A5, NHE5
Domain Architecture
Description	Sodium/hydrogen exchanger 5 (Na(+)/H(+) exchanger 5) (NHE-5) (Solute carrier family 9 member 5).

TBC13_MOUSE
θ value	1.81305 (rank : 54)	NC score	0.299471 (rank : 25)
Query Neighborhood Hits	94	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R3D1	Gene names	Tbc1d13
Domain Architecture
Description	TBC1 domain family member 13.

ZC313_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.021191 (rank : 62)
Query Neighborhood Hits	94	Target Neighborhood Hits	772	Shared Neighborhood Hits	16
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

ACHA4_HUMAN
θ value	2.36792 (rank : 56)	NC score	0.006044 (rank : 97)
Query Neighborhood Hits	94	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	P43681, Q4JGR7	Gene names	CHRNA4, NACRA4
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-4 precursor.

HXD3_HUMAN
θ value	2.36792 (rank : 57)	NC score	0.009399 (rank : 89)
Query Neighborhood Hits	94	Target Neighborhood Hits	433	Shared Neighborhood Hits	9
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

SATB1_MOUSE
θ value	2.36792 (rank : 58)	NC score	0.032028 (rank : 41)
Query Neighborhood Hits	94	Target Neighborhood Hits	130	Shared Neighborhood Hits	9
SwissProt Accessions	Q60611	Gene names	Satb1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

SFR11_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.027063 (rank : 50)
Query Neighborhood Hits	94	Target Neighborhood Hits	246	Shared Neighborhood Hits	8
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

SPEG_MOUSE
θ value	2.36792 (rank : 60)	NC score	0.007282 (rank : 93)
Query Neighborhood Hits	94	Target Neighborhood Hits	1959	Shared Neighborhood Hits	36
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SYNJ1_MOUSE
θ value	2.36792 (rank : 61)	NC score	0.018584 (rank : 71)
Query Neighborhood Hits	94	Target Neighborhood Hits	516	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ADDB_MOUSE
θ value	3.0926 (rank : 62)	NC score	0.019921 (rank : 67)
Query Neighborhood Hits	94	Target Neighborhood Hits	574	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

PDZD8_HUMAN
θ value	3.0926 (rank : 63)	NC score	0.021078 (rank : 64)
Query Neighborhood Hits	94	Target Neighborhood Hits	185	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

TJAP1_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.017787 (rank : 75)
Query Neighborhood Hits	94	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q5JTD0, Q5JTD1, Q5JWW1, Q68DB2, Q6P2P3, Q9H7V7	Gene names	TJAP1, PILT, TJP4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

WNK1_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.001451 (rank : 100)
Query Neighborhood Hits	94	Target Neighborhood Hits	1158	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

ADDB_HUMAN
θ value	4.03905 (rank : 66)	NC score	0.016722 (rank : 77)
Query Neighborhood Hits	94	Target Neighborhood Hits	142	Shared Neighborhood Hits	6
SwissProt Accessions	P35612, Q13482, Q16412, Q59G82, Q5U5P4, Q6P0P2, Q6PGQ4, Q7Z688, Q7Z689, Q7Z690, Q7Z691	Gene names	ADD2, ADDB
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta).

AF17_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.010494 (rank : 86)
Query Neighborhood Hits	94	Target Neighborhood Hits	230	Shared Neighborhood Hits	10
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

BMP8B_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.009138 (rank : 90)
Query Neighborhood Hits	94	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	P55105	Gene names	Bmp8b
Domain Architecture
Description	Bone morphogenetic protein 8B precursor (BMP-8B).

BSN_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.024640 (rank : 57)
Query Neighborhood Hits	94	Target Neighborhood Hits	1537	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CAC1E_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.006987 (rank : 95)
Query Neighborhood Hits	94	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

G3BP2_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.020648 (rank : 66)
Query Neighborhood Hits	94	Target Neighborhood Hits	260	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UN86, O60606, O75149, Q9UPA1	Gene names	G3BP2, KIAA0660
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

K1543_HUMAN
θ value	4.03905 (rank : 72)	NC score	0.029030 (rank : 44)
Query Neighborhood Hits	94	Target Neighborhood Hits	435	Shared Neighborhood Hits	23
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

TCOF_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.027106 (rank : 49)
Query Neighborhood Hits	94	Target Neighborhood Hits	543	Shared Neighborhood Hits	18
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

BAT3_HUMAN
θ value	5.27518 (rank : 74)	NC score	0.018496 (rank : 72)
Query Neighborhood Hits	94	Target Neighborhood Hits	490	Shared Neighborhood Hits	17
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

K0999_MOUSE
θ value	5.27518 (rank : 75)	NC score	-0.001038 (rank : 101)
Query Neighborhood Hits	94	Target Neighborhood Hits	931	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).

MAP4_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.022083 (rank : 61)
Query Neighborhood Hits	94	Target Neighborhood Hits	428	Shared Neighborhood Hits	23
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MILK2_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.009032 (rank : 91)
Query Neighborhood Hits	94	Target Neighborhood Hits	457	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

SRRM1_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.044622 (rank : 38)
Query Neighborhood Hits	94	Target Neighborhood Hits	690	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

BAZ1A_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.016450 (rank : 78)
Query Neighborhood Hits	94	Target Neighborhood Hits	693	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

CD2AP_MOUSE
θ value	6.88961 (rank : 80)	NC score	0.005435 (rank : 99)
Query Neighborhood Hits	94	Target Neighborhood Hits	336	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

GP158_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.009413 (rank : 87)
Query Neighborhood Hits	94	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

LCTL_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.012133 (rank : 85)
Query Neighborhood Hits	94	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q6UWM7	Gene names	LCTL, KLPH
Domain Architecture	No domain graphic available
Description	Lactase-like protein precursor (Klotho/lactase-phlorizin hydrolase- related protein).

MORC2_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.009410 (rank : 88)
Query Neighborhood Hits	94	Target Neighborhood Hits	207	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

MUC1_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.019795 (rank : 68)
Query Neighborhood Hits	94	Target Neighborhood Hits	975	Shared Neighborhood Hits	32
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

RABE2_MOUSE
θ value	6.88961 (rank : 85)	NC score	0.013220 (rank : 84)
Query Neighborhood Hits	94	Target Neighborhood Hits	598	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

SYN1_MOUSE
θ value	6.88961 (rank : 86)	NC score	0.015287 (rank : 80)
Query Neighborhood Hits	94	Target Neighborhood Hits	363	Shared Neighborhood Hits	18
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

TAF9_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.027317 (rank : 48)
Query Neighborhood Hits	94	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VI33, Q32P09, Q80XS3, Q9CV61	Gene names	Taf9, Taf2g
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32).

ZMY10_MOUSE
θ value	6.88961 (rank : 88)	NC score	0.018202 (rank : 73)
Query Neighborhood Hits	94	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q99ML0, Q80W73	Gene names	Zmynd10, Blu
Domain Architecture
Description	Zinc finger MYND domain-containing protein 10 (BLu protein).

ATX7_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.013680 (rank : 83)
Query Neighborhood Hits	94	Target Neighborhood Hits	328	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

CAC1B_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.005900 (rank : 98)
Query Neighborhood Hits	94	Target Neighborhood Hits	257	Shared Neighborhood Hits	10
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

HXA3_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.006058 (rank : 96)
Query Neighborhood Hits	94	Target Neighborhood Hits	535	Shared Neighborhood Hits	19
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

K1543_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.025190 (rank : 56)
Query Neighborhood Hits	94	Target Neighborhood Hits	497	Shared Neighborhood Hits	21
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

NACAM_MOUSE
θ value	8.99809 (rank : 93)	NC score	0.028830 (rank : 45)
Query Neighborhood Hits	94	Target Neighborhood Hits	1866	Shared Neighborhood Hits	48
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TOB1_MOUSE
θ value	8.99809 (rank : 94)	NC score	0.007087 (rank : 94)
Query Neighborhood Hits	94	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q61471	Gene names	Tob1, Tob, Trob
Domain Architecture
Description	Tob1 protein (Transducer of erbB-2 1).

GRAM3_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.054275 (rank : 35)
Query Neighborhood Hits	94	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q96HH9, Q9H753	Gene names	GRAMD3, NS3TP2
Domain Architecture	No domain graphic available
Description	GRAM domain-containing protein 3 (HCV NS3-transactivated protein 2).

GRAM3_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.054256 (rank : 36)
Query Neighborhood Hits	94	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PEM6	Gene names	Gramd3
Domain Architecture	No domain graphic available
Description	GRAM domain-containing protein 3.

TBC13_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.124578 (rank : 31)
Query Neighborhood Hits	94	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NVG8	Gene names	TBC1D13
Domain Architecture
Description	TBC1 domain family member 13.

TBC20_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.056411 (rank : 33)
Query Neighborhood Hits	94	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q96BZ9, Q5JWQ7, Q96NE1, Q9BYM7, Q9H140	Gene names	TBC1D20, C20orf140
Domain Architecture
Description	TBC1 domain family member 20.

TBC20_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.055581 (rank : 34)
Query Neighborhood Hits	94	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D9I4, Q3TYW9, Q99LW2	Gene names	Tbc1d20
Domain Architecture
Description	TBC1 domain family member 20.

TBC21_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.163931 (rank : 28)
Query Neighborhood Hits	94	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IYX1	Gene names	TBC1D21
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 21.

UBP32_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.061107 (rank : 32)
Query Neighborhood Hits	94	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

Hits sorted by NC score

TBC10_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	94	Target Neighborhood Hits	94	Shared Neighborhood Hits	94
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

TBC10_HUMAN
NC score	0.988274 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	94	Target Neighborhood Hits	64	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BXI6, O76053, Q543A2	Gene names	TBC1D10A, EPI64, TBC1D10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

US6NL_MOUSE
NC score	0.805776 (rank : 3)	θ value	9.8567e-31 (rank : 4)
Query Neighborhood Hits	94	Target Neighborhood Hits	157	Shared Neighborhood Hits	34
SwissProt Accessions	Q80XC3, Q6ZQK8	Gene names	Usp6nl, Kiaa0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein.

US6NL_HUMAN
NC score	0.798564 (rank : 4)	θ value	4.89182e-30 (rank : 5)
Query Neighborhood Hits	94	Target Neighborhood Hits	201	Shared Neighborhood Hits	37
SwissProt Accessions	Q92738, Q15400, Q7L0K9	Gene names	USP6NL, KIAA0019
Domain Architecture	No domain graphic available
Description	USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN- tre).

TBCD3_HUMAN
NC score	0.756895 (rank : 5)	θ value	2.20094e-22 (rank : 13)
Query Neighborhood Hits	94	Target Neighborhood Hits	51	Shared Neighborhood Hits	21
SwissProt Accessions	Q8IZP1, Q9H0B9, Q9UDD4	Gene names	TBC1D3, PRC17
Domain Architecture
Description	TBC1 domain family member 3 (Rab GTPase-activating protein PRC17) (Prostate cancer gene 17 protein) (TRE17 alpha protein).

TBCD8_MOUSE
NC score	0.756369 (rank : 6)	θ value	5.77852e-31 (rank : 3)
Query Neighborhood Hits	94	Target Neighborhood Hits	64	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z1A9	Gene names	Tbc1d8, Hblp1, Vrp
Domain Architecture
Description	TBC1 domain family member 8 (Vascular Rab-GAP/TBC-containing protein) (BUB2-like protein 1).

TBCD8_HUMAN
NC score	0.748758 (rank : 7)	θ value	1.08979e-29 (rank : 6)
Query Neighborhood Hits	94	Target Neighborhood Hits	65	Shared Neighborhood Hits	22
SwissProt Accessions	O95759, Q9UQ32	Gene names	TBC1D8, VRP
Domain Architecture
Description	TBC1 domain family member 8 (Vascular Rab-GAP/TBC-containing protein) (AD 3).

TBC12_HUMAN
NC score	0.743441 (rank : 8)	θ value	2.27762e-19 (rank : 14)
Query Neighborhood Hits	94	Target Neighborhood Hits	80	Shared Neighborhood Hits	29
SwissProt Accessions	O60347, Q5VYA6, Q8WX26, Q8WX59, Q9UG83	Gene names	TBC1D12, KIAA0608
Domain Architecture
Description	TBC1 domain family member 12.

TBCD1_HUMAN
NC score	0.739316 (rank : 9)	θ value	9.54697e-26 (rank : 9)
Query Neighborhood Hits	94	Target Neighborhood Hits	276	Shared Neighborhood Hits	32
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

TBCD1_MOUSE
NC score	0.731423 (rank : 10)	θ value	6.18819e-25 (rank : 10)
Query Neighborhood Hits	94	Target Neighborhood Hits	241	Shared Neighborhood Hits	30
SwissProt Accessions	Q60949, Q80TJ9, Q923F8	Gene names	Tbc1d1, Kiaa1108, Tbc1
Domain Architecture
Description	TBC1 domain family member 1.

TBCD4_MOUSE
NC score	0.716757 (rank : 11)	θ value	1.02001e-27 (rank : 7)
Query Neighborhood Hits	94	Target Neighborhood Hits	276	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BYJ6, Q5DU23, Q66JU2, Q6P2M2, Q8BMH6, Q8BXM2	Gene names	Tbc1d4, Kiaa0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TBC14_HUMAN
NC score	0.715431 (rank : 12)	θ value	5.07402e-19 (rank : 15)
Query Neighborhood Hits	94	Target Neighborhood Hits	124	Shared Neighborhood Hits	30
SwissProt Accessions	Q9P2M4, Q8IW15	Gene names	TBC1D14, KIAA1322
Domain Architecture
Description	TBC1 domain family member 14.

TBC14_MOUSE
NC score	0.710303 (rank : 13)	θ value	1.92812e-18 (rank : 16)
Query Neighborhood Hits	94	Target Neighborhood Hits	135	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CGA2, Q8CHA5	Gene names	Tbc1d14, D5Ertd110e, Kiaa1322
Domain Architecture
Description	TBC1 domain family member 14.

TBCD4_HUMAN
NC score	0.704490 (rank : 14)	θ value	1.47289e-26 (rank : 8)
Query Neighborhood Hits	94	Target Neighborhood Hits	357	Shared Neighborhood Hits	27
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TBCD2_HUMAN
NC score	0.681383 (rank : 15)	θ value	5.23862e-24 (rank : 11)
Query Neighborhood Hits	94	Target Neighborhood Hits	419	Shared Neighborhood Hits	34
SwissProt Accessions	Q9BYX2	Gene names	TBC1D2, PARIS1
Domain Architecture
Description	TBC1 domain family member 2 (Prostate antigen recognized and identified by SEREX) (PARIS-1).

TBC16_HUMAN
NC score	0.571164 (rank : 16)	θ value	8.97725e-08 (rank : 20)
Query Neighborhood Hits	94	Target Neighborhood Hits	55	Shared Neighborhood Hits	30
SwissProt Accessions	Q8TBP0	Gene names	TBC1D16
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 16.

TBC15_MOUSE
NC score	0.476731 (rank : 17)	θ value	2.13673e-09 (rank : 17)
Query Neighborhood Hits	94	Target Neighborhood Hits	40	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CXF4, Q3UI41	Gene names	Tbc1d15
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 15.

TBC15_HUMAN
NC score	0.468996 (rank : 18)	θ value	1.38499e-08 (rank : 19)
Query Neighborhood Hits	94	Target Neighborhood Hits	36	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TC07	Gene names	TBC1D15
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 15.

TBC17_HUMAN
NC score	0.466730 (rank : 19)	θ value	2.79066e-09 (rank : 18)
Query Neighborhood Hits	94	Target Neighborhood Hits	60	Shared Neighborhood Hits	27
SwissProt Accessions	Q9HA65	Gene names	TBC1D17
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 17.

TBC17_MOUSE
NC score	0.466480 (rank : 20)	θ value	1.53129e-07 (rank : 21)
Query Neighborhood Hits	94	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q8BYH7	Gene names	Tbc1d17
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 17.

UBP6_HUMAN
NC score	0.447868 (rank : 21)	θ value	3.39556e-23 (rank : 12)
Query Neighborhood Hits	94	Target Neighborhood Hits	188	Shared Neighborhood Hits	25
SwissProt Accessions	P35125, Q15634, Q86WP6, Q8IWT4	Gene names	USP6, TRE2
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 6 (EC 3.1.2.15) (Ubiquitin thioesterase 6) (Ubiquitin-specific-processing protease 6) (Deubiquitinating enzyme 6) (Proto-oncogene TRE-2).

TB22B_HUMAN
NC score	0.363734 (rank : 22)	θ value	0.00134147 (rank : 25)
Query Neighborhood Hits	94	Target Neighborhood Hits	35	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NU19, Q5VUK9, Q7Z6P7, Q9BPV6, Q9BUT5, Q9NXB6	Gene names	TBC1D22B, C6orf197
Domain Architecture
Description	TBC1 domain family member 22B.

TB22A_MOUSE
NC score	0.341428 (rank : 23)	θ value	0.00228821 (rank : 26)
Query Neighborhood Hits	94	Target Neighborhood Hits	42	Shared Neighborhood Hits	24
SwissProt Accessions	Q8R5A6, Q3U268, Q3U3T0, Q8CA49	Gene names	Tbc1d22a, D15Ertd781e
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 22A.

TB22A_HUMAN
NC score	0.340577 (rank : 24)	θ value	0.00102713 (rank : 23)
Query Neighborhood Hits	94	Target Neighborhood Hits	34	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WUA7, Q5TE47, Q6ZUH2, Q92680, Q9BVD6, Q9UGG0, Q9UGT2, Q9UGU6, Q9UH25, Q9Y4W5	Gene names	TBC1D22A, C22orf4
Domain Architecture
Description	TBC1 domain family member 22A.

TBC13_MOUSE
NC score	0.299471 (rank : 25)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	94	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R3D1	Gene names	Tbc1d13
Domain Architecture
Description	TBC1 domain family member 13.

TBCD5_HUMAN
NC score	0.293398 (rank : 26)	θ value	0.000461057 (rank : 22)
Query Neighborhood Hits	94	Target Neighborhood Hits	70	Shared Neighborhood Hits	23
SwissProt Accessions	Q92609	Gene names	TBC1D5, KIAA0210
Domain Architecture
Description	TBC1 domain family member 5.

TBCD5_MOUSE
NC score	0.274468 (rank : 27)	θ value	0.00102713 (rank : 24)
Query Neighborhood Hits	94	Target Neighborhood Hits	71	Shared Neighborhood Hits	22
SwissProt Accessions	Q80XQ2	Gene names	Tbc1d5
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 5.

TBC21_HUMAN
NC score	0.163931 (rank : 28)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	94	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IYX1	Gene names	TBC1D21
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 21.

TBCD7_MOUSE
NC score	0.137605 (rank : 29)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	94	Target Neighborhood Hits	18	Shared Neighborhood Hits	14
SwissProt Accessions	Q9D0K0, Q3U0V0	Gene names	Tbc1d7
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 7.

TBCD7_HUMAN
NC score	0.136912 (rank : 30)	θ value	0.365318 (rank : 33)
Query Neighborhood Hits	94	Target Neighborhood Hits	14	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P0N9	Gene names	TBC1D7
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 7.

TBC13_HUMAN
NC score	0.124578 (rank : 31)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	94	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NVG8	Gene names	TBC1D13
Domain Architecture
Description	TBC1 domain family member 13.

UBP32_HUMAN
NC score	0.061107 (rank : 32)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	94	Target Neighborhood Hits	170	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

TBC20_HUMAN
NC score	0.056411 (rank : 33)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	94	Target Neighborhood Hits	16	Shared Neighborhood Hits	9
SwissProt Accessions	Q96BZ9, Q5JWQ7, Q96NE1, Q9BYM7, Q9H140	Gene names	TBC1D20, C20orf140
Domain Architecture
Description	TBC1 domain family member 20.

TBC20_MOUSE
NC score	0.055581 (rank : 34)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	94	Target Neighborhood Hits	17	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D9I4, Q3TYW9, Q99LW2	Gene names	Tbc1d20
Domain Architecture
Description	TBC1 domain family member 20.

GRAM3_HUMAN
NC score	0.054275 (rank : 35)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	94	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q96HH9, Q9H753	Gene names	GRAMD3, NS3TP2
Domain Architecture	No domain graphic available
Description	GRAM domain-containing protein 3 (HCV NS3-transactivated protein 2).

GRAM3_MOUSE
NC score	0.054256 (rank : 36)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	94	Target Neighborhood Hits	24	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PEM6	Gene names	Gramd3
Domain Architecture	No domain graphic available
Description	GRAM domain-containing protein 3.

SRRM1_MOUSE
NC score	0.044852 (rank : 37)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	94	Target Neighborhood Hits	966	Shared Neighborhood Hits	34
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

SRRM1_HUMAN
NC score	0.044622 (rank : 38)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	94	Target Neighborhood Hits	690	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

TAF9_HUMAN
NC score	0.040202 (rank : 39)	θ value	0.21417 (rank : 29)
Query Neighborhood Hits	94	Target Neighborhood Hits	41	Shared Neighborhood Hits	7
SwissProt Accessions	Q16594, Q9BTS1	Gene names	TAF9, TAF2G, TAFII31
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32) (STAF31/32).

SATB1_HUMAN
NC score	0.034335 (rank : 40)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	94	Target Neighborhood Hits	130	Shared Neighborhood Hits	8
SwissProt Accessions	Q01826	Gene names	SATB1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

SATB1_MOUSE
NC score	0.032028 (rank : 41)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	94	Target Neighborhood Hits	130	Shared Neighborhood Hits	9
SwissProt Accessions	Q60611	Gene names	Satb1
Domain Architecture
Description	DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1).

PRG4_MOUSE
NC score	0.030130 (rank : 42)	θ value	0.365318 (rank : 32)
Query Neighborhood Hits	94	Target Neighborhood Hits	624	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

LETM1_MOUSE
NC score	0.029051 (rank : 43)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	94	Target Neighborhood Hits	240	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z2I0, Q5PQC5, Q7TMK8, Q80ZX6, Q8CGJ3, Q8K5E5	Gene names	Letm1
Domain Architecture	No domain graphic available
Description	Leucine zipper-EF-hand-containing transmembrane protein 1, mitochondrial precursor.

K1543_HUMAN
NC score	0.029030 (rank : 44)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	94	Target Neighborhood Hits	435	Shared Neighborhood Hits	23
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

NACAM_MOUSE
NC score	0.028830 (rank : 45)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	94	Target Neighborhood Hits	1866	Shared Neighborhood Hits	48
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TTC15_HUMAN
NC score	0.028190 (rank : 46)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	94	Target Neighborhood Hits	112	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WVT3, Q8WVW1, Q9Y395	Gene names	TTC15
Domain Architecture
Description	Tetratricopeptide repeat protein 15 (TPR repeat protein 15).

PRG4_HUMAN
NC score	0.027996 (rank : 47)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	94	Target Neighborhood Hits	764	Shared Neighborhood Hits	26
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

TAF9_MOUSE
NC score	0.027317 (rank : 48)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	94	Target Neighborhood Hits	69	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VI33, Q32P09, Q80XS3, Q9CV61	Gene names	Taf9, Taf2g
Domain Architecture
Description	Transcription initiation factor TFIID subunit 9 (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII-32) (TAFII32).

TCOF_HUMAN
NC score	0.027106 (rank : 49)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	94	Target Neighborhood Hits	543	Shared Neighborhood Hits	18
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

SFR11_HUMAN
NC score	0.027063 (rank : 50)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	94	Target Neighborhood Hits	246	Shared Neighborhood Hits	8
SwissProt Accessions	Q05519	Gene names	SFRS11
Domain Architecture
Description	Splicing factor arginine/serine-rich 11 (Arginine-rich 54 kDa nuclear protein) (p54).

CNOT3_MOUSE
NC score	0.026667 (rank : 51)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	94	Target Neighborhood Hits	504	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

PCLO_MOUSE
NC score	0.026578 (rank : 52)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	94	Target Neighborhood Hits	2275	Shared Neighborhood Hits	44
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RGS3_HUMAN
NC score	0.026573 (rank : 53)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	94	Target Neighborhood Hits	1375	Shared Neighborhood Hits	38
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

3BP2_HUMAN
NC score	0.025726 (rank : 54)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	94	Target Neighborhood Hits	296	Shared Neighborhood Hits	12
SwissProt Accessions	P78314, O00500, O15373, P78315	Gene names	SH3BP2, 3BP2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

MLL4_HUMAN
NC score	0.025347 (rank : 55)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	94	Target Neighborhood Hits	722	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

K1543_MOUSE
NC score	0.025190 (rank : 56)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	94	Target Neighborhood Hits	497	Shared Neighborhood Hits	21
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

BSN_HUMAN
NC score	0.024640 (rank : 57)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	94	Target Neighborhood Hits	1537	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

FA61A_MOUSE
NC score	0.023954 (rank : 58)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	94	Target Neighborhood Hits	81	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K2F8, Q9CTG8	Gene names	Fam61a
Domain Architecture	No domain graphic available
Description	Protein FAM61A.

G3BP2_MOUSE
NC score	0.023576 (rank : 59)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	94	Target Neighborhood Hits	258	Shared Neighborhood Hits	7
SwissProt Accessions	P97379, Q9R1B8	Gene names	G3bp2
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

AFF3_HUMAN
NC score	0.022573 (rank : 60)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	94	Target Neighborhood Hits	190	Shared Neighborhood Hits	8
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

MAP4_HUMAN
NC score	0.022083 (rank : 61)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	94	Target Neighborhood Hits	428	Shared Neighborhood Hits	23
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

ZC313_HUMAN
NC score	0.021191 (rank : 62)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	94	Target Neighborhood Hits	772	Shared Neighborhood Hits	16
SwissProt Accessions	Q5T200, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6	Gene names	ZC3H13, KIAA0853
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 13.

RP1L1_MOUSE
NC score	0.021161 (rank : 63)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	94	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

PDZD8_HUMAN
NC score	0.021078 (rank : 64)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	94	Target Neighborhood Hits	185	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

APBA3_HUMAN
NC score	0.020979 (rank : 65)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	94	Target Neighborhood Hits	201	Shared Neighborhood Hits	6
SwissProt Accessions	O96018, O60483	Gene names	APBA3, MINT3, X11L2
Domain Architecture
Description	Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma).

G3BP2_HUMAN
NC score	0.020648 (rank : 66)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	94	Target Neighborhood Hits	260	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UN86, O60606, O75149, Q9UPA1	Gene names	G3BP2, KIAA0660
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

ADDB_MOUSE
NC score	0.019921 (rank : 67)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	94	Target Neighborhood Hits	574	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

MUC1_HUMAN
NC score	0.019795 (rank : 68)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	94	Target Neighborhood Hits	975	Shared Neighborhood Hits	32
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

CSKI1_HUMAN
NC score	0.019428 (rank : 69)	θ value	0.21417 (rank : 28)
Query Neighborhood Hits	94	Target Neighborhood Hits	997	Shared Neighborhood Hits	28
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

DLG5_HUMAN
NC score	0.019238 (rank : 70)	θ value	0.0961366 (rank : 27)
Query Neighborhood Hits	94	Target Neighborhood Hits	1088	Shared Neighborhood Hits	25
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

SYNJ1_MOUSE
NC score	0.018584 (rank : 71)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	94	Target Neighborhood Hits	516	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

BAT3_HUMAN
NC score	0.018496 (rank : 72)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	94	Target Neighborhood Hits	490	Shared Neighborhood Hits	17
SwissProt Accessions	P46379, O95874, Q5SQ35, Q5SQ36, Q5SQ37, Q5SRP8, Q96SA6, Q9BCN4	Gene names	BAT3, G3
Domain Architecture
Description	Large proline-rich protein BAT3 (HLA-B-associated transcript 3) (Protein G3).

ZMY10_MOUSE
NC score	0.018202 (rank : 73)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	94	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	Q99ML0, Q80W73	Gene names	Zmynd10, Blu
Domain Architecture
Description	Zinc finger MYND domain-containing protein 10 (BLu protein).

ATBF1_MOUSE
NC score	0.018061 (rank : 74)	θ value	0.279714 (rank : 30)
Query Neighborhood Hits	94	Target Neighborhood Hits	1841	Shared Neighborhood Hits	29
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

TJAP1_HUMAN
NC score	0.017787 (rank : 75)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	94	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q5JTD0, Q5JTD1, Q5JWW1, Q68DB2, Q6P2P3, Q9H7V7	Gene names	TJAP1, PILT, TJP4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

BPTF_HUMAN
NC score	0.016899 (rank : 76)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	94	Target Neighborhood Hits	786	Shared Neighborhood Hits	18
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

ADDB_HUMAN
NC score	0.016722 (rank : 77)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	94	Target Neighborhood Hits	142	Shared Neighborhood Hits	6
SwissProt Accessions	P35612, Q13482, Q16412, Q59G82, Q5U5P4, Q6P0P2, Q6PGQ4, Q7Z688, Q7Z689, Q7Z690, Q7Z691	Gene names	ADD2, ADDB
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta).

BAZ1A_HUMAN
NC score	0.016450 (rank : 78)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	94	Target Neighborhood Hits	693	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

SL9A5_HUMAN
NC score	0.015296 (rank : 79)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	94	Target Neighborhood Hits	55	Shared Neighborhood Hits	4
SwissProt Accessions	Q14940, Q9Y626	Gene names	SLC9A5, NHE5
Domain Architecture
Description	Sodium/hydrogen exchanger 5 (Na(+)/H(+) exchanger 5) (NHE-5) (Solute carrier family 9 member 5).

SYN1_MOUSE
NC score	0.015287 (rank : 80)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	94	Target Neighborhood Hits	363	Shared Neighborhood Hits	18
SwissProt Accessions	O88935, Q62279, Q8QZT8	Gene names	Syn1, Syn-1
Domain Architecture
Description	Synapsin-1 (Synapsin I).

ATBF1_HUMAN
NC score	0.015130 (rank : 81)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	94	Target Neighborhood Hits	1547	Shared Neighborhood Hits	22
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

PDLI5_MOUSE
NC score	0.015114 (rank : 82)	θ value	0.279714 (rank : 31)
Query Neighborhood Hits	94	Target Neighborhood Hits	287	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CI51, Q9QYN0, Q9QYN1, Q9QYN2	Gene names	Pdlim5, Enh
Domain Architecture
Description	PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein).

ATX7_MOUSE
NC score	0.013680 (rank : 83)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	94	Target Neighborhood Hits	328	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R4I1, Q8BL17	Gene names	Atxn7, Sca7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein homolog).

RABE2_MOUSE
NC score	0.013220 (rank : 84)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	94	Target Neighborhood Hits	598	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

LCTL_HUMAN
NC score	0.012133 (rank : 85)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	94	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q6UWM7	Gene names	LCTL, KLPH
Domain Architecture	No domain graphic available
Description	Lactase-like protein precursor (Klotho/lactase-phlorizin hydrolase- related protein).

AF17_HUMAN
NC score	0.010494 (rank : 86)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	94	Target Neighborhood Hits	230	Shared Neighborhood Hits	10
SwissProt Accessions	P55198, Q9UF49	Gene names	MLLT6, AF17
Domain Architecture
Description	Protein AF-17.

GP158_MOUSE
NC score	0.009413 (rank : 87)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	94	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

MORC2_HUMAN
NC score	0.009410 (rank : 88)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	94	Target Neighborhood Hits	207	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

HXD3_HUMAN
NC score	0.009399 (rank : 89)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	94	Target Neighborhood Hits	433	Shared Neighborhood Hits	9
SwissProt Accessions	P31249, Q99955, Q9BSC5	Gene names	HOXD3, HOX4A
Domain Architecture
Description	Homeobox protein Hox-D3 (Hox-4A).

BMP8B_MOUSE
NC score	0.009138 (rank : 90)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	94	Target Neighborhood Hits	70	Shared Neighborhood Hits	3
SwissProt Accessions	P55105	Gene names	Bmp8b
Domain Architecture
Description	Bone morphogenetic protein 8B precursor (BMP-8B).

MILK2_HUMAN
NC score	0.009032 (rank : 91)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	94	Target Neighborhood Hits	457	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

SPEG_HUMAN
NC score	0.008150 (rank : 92)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	94	Target Neighborhood Hits	1762	Shared Neighborhood Hits	30
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

SPEG_MOUSE
NC score	0.007282 (rank : 93)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	94	Target Neighborhood Hits	1959	Shared Neighborhood Hits	36
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TOB1_MOUSE
NC score	0.007087 (rank : 94)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	94	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q61471	Gene names	Tob1, Tob, Trob
Domain Architecture
Description	Tob1 protein (Transducer of erbB-2 1).

CAC1E_MOUSE
NC score	0.006987 (rank : 95)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	94	Target Neighborhood Hits	167	Shared Neighborhood Hits	4
SwissProt Accessions	Q61290	Gene names	Cacna1e, Cach6, Cacnl1a6, Cchra1
Domain Architecture
Description	Voltage-dependent R-type calcium channel subunit alpha-1E (Voltage- gated calcium channel subunit alpha Cav2.3) (Calcium channel, L type, alpha-1 polypeptide, isoform 6) (Brain calcium channel II) (BII).

HXA3_HUMAN
NC score	0.006058 (rank : 96)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	94	Target Neighborhood Hits	535	Shared Neighborhood Hits	19
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

ACHA4_HUMAN
NC score	0.006044 (rank : 97)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	94	Target Neighborhood Hits	131	Shared Neighborhood Hits	5
SwissProt Accessions	P43681, Q4JGR7	Gene names	CHRNA4, NACRA4
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-4 precursor.

CAC1B_HUMAN
NC score	0.005900 (rank : 98)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	94	Target Neighborhood Hits	257	Shared Neighborhood Hits	10
SwissProt Accessions	Q00975	Gene names	CACNA1B, CACH5, CACNL1A5
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CD2AP_MOUSE
NC score	0.005435 (rank : 99)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	94	Target Neighborhood Hits	336	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JLQ0, O88903, Q8K4Z1, Q8VCI9	Gene names	Cd2ap, Mets1
Domain Architecture
Description	CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1).

WNK1_HUMAN
NC score	0.001451 (rank : 100)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	94	Target Neighborhood Hits	1158	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

K0999_MOUSE
NC score	-0.001038 (rank : 101)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	94	Target Neighborhood Hits	931	Shared Neighborhood Hits	10
SwissProt Accessions	Q6P4S6, Q641L5, Q66JZ5, Q6ZQ09, Q8K075, Q9CYD5	Gene names	Kiaa0999
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase KIAA0999 (EC 2.7.11.1).