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Network neighborhood for query Sequence : STON2_HUMAN

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STON2_HUMAN
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

STON2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	115	Target Neighborhood Hits	115	Shared Neighborhood Hits	115
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

STON2_MOUSE
θ value	0 (rank : 2)	NC score	0.973763 (rank : 2)
Query Neighborhood Hits	115	Target Neighborhood Hits	75	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BZ60	Gene names	Ston2, Stn2, Stnb
Domain Architecture
Description	Stonin-2 (Stoned B).

STON1_MOUSE
θ value	1.58745e-113 (rank : 3)	NC score	0.904887 (rank : 4)
Query Neighborhood Hits	115	Target Neighborhood Hits	50	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CDJ8, Q8CDL8, Q9D5T3	Gene names	Ston1, Salf, Sblf, Stn1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

STON1_HUMAN
θ value	2.70778e-113 (rank : 4)	NC score	0.906721 (rank : 3)
Query Neighborhood Hits	115	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6Q2, Q96JE3, Q9BYX3	Gene names	STON1, SALF, SBLF, STN1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

AP2M1_HUMAN
θ value	1.09485e-13 (rank : 5)	NC score	0.469648 (rank : 5)
Query Neighborhood Hits	115	Target Neighborhood Hits	33	Shared Neighborhood Hits	11
SwissProt Accessions	Q96CW1, P20172, P53679	Gene names	AP2M1, CLAPM1, KIAA0109
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit mu-1 (Adaptin mu-1) (AP-2 mu-2 chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Plasma membrane adaptor AP-2 50 kDa protein) (HA2 50 kDa subunit) (Clathrin assembly protein complex 2 medium chain).

AP2M1_MOUSE
θ value	1.09485e-13 (rank : 6)	NC score	0.469648 (rank : 6)
Query Neighborhood Hits	115	Target Neighborhood Hits	33	Shared Neighborhood Hits	11
SwissProt Accessions	P84091, P20172, P53679	Gene names	Ap2m1, Clapm1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit mu-1 (Adaptin mu-1) (AP-2 mu-2 chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Plasma membrane adaptor AP-2 50 kDa protein) (Clathrin assembly protein complex 2 medium chain).

AP1M1_HUMAN
θ value	1.42992e-13 (rank : 7)	NC score	0.460841 (rank : 7)
Query Neighborhood Hits	115	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BXS5	Gene names	AP1M1, CLTNM
Domain Architecture
Description	AP-1 complex subunit mu-1 (Adaptor-related protein complex 1 mu-1 subunit) (Mu-adaptin 1) (Adaptor protein complex AP-1 mu-1 subunit) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 1) (AP-mu chain family member mu1A) (Clathrin coat assembly protein AP47) (Clathrin coat- associated protein AP47).

AP1M1_MOUSE
θ value	3.18553e-13 (rank : 8)	NC score	0.458140 (rank : 8)
Query Neighborhood Hits	115	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	P35585	Gene names	Ap1m1, Cltnm
Domain Architecture
Description	AP-1 complex subunit mu-1 (Adaptor-related protein complex 1 mu-1 subunit) (Mu-adaptin 1) (Adaptor protein complex AP-1 mu-1 subunit) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 1) (AP-mu chain family member mu1A) (Clathrin coat assembly protein AP47) (Clathrin coat- associated protein AP47).

AP1M2_HUMAN
θ value	5.43371e-13 (rank : 9)	NC score	0.448017 (rank : 9)
Query Neighborhood Hits	115	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y6Q5, Q9BSI8	Gene names	AP1M2
Domain Architecture
Description	AP-1 complex subunit mu-2 (Adaptor-related protein complex 1 mu-2 subunit) (Mu-adaptin 2) (Adaptor protein complex AP-1 mu-2 subunit) (Golgi adaptor HA1/AP1 adaptin mu-2 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 2) (AP-mu chain family member mu1B).

AP1M2_MOUSE
θ value	9.26847e-13 (rank : 10)	NC score	0.447466 (rank : 10)
Query Neighborhood Hits	115	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WVP1, Q99LA4, Q9CWP7	Gene names	Ap1m2
Domain Architecture
Description	AP-1 complex subunit mu-2 (Adaptor-related protein complex 1 mu-2 subunit) (Mu-adaptin 2) (Adaptor protein complex AP-1 mu-2 subunit) (Golgi adaptor HA1/AP1 adaptin mu-2 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 2) (AP-mu chain family member mu1B).

ECM2_HUMAN
θ value	0.000270298 (rank : 11)	NC score	0.040513 (rank : 36)
Query Neighborhood Hits	115	Target Neighborhood Hits	402	Shared Neighborhood Hits	8
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

LMO7_HUMAN
θ value	0.00228821 (rank : 12)	NC score	0.070160 (rank : 20)
Query Neighborhood Hits	115	Target Neighborhood Hits	507	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

SRRM2_HUMAN
θ value	0.00298849 (rank : 13)	NC score	0.055764 (rank : 25)
Query Neighborhood Hits	115	Target Neighborhood Hits	1296	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

SET1A_HUMAN
θ value	0.00390308 (rank : 14)	NC score	0.061615 (rank : 23)
Query Neighborhood Hits	115	Target Neighborhood Hits	690	Shared Neighborhood Hits	26
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

AFF1_MOUSE
θ value	0.00665767 (rank : 15)	NC score	0.072474 (rank : 19)
Query Neighborhood Hits	115	Target Neighborhood Hits	351	Shared Neighborhood Hits	18
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

AP4M1_HUMAN
θ value	0.0113563 (rank : 16)	NC score	0.304589 (rank : 11)
Query Neighborhood Hits	115	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	O00189, Q9UHK9	Gene names	AP4M1, MUARP2
Domain Architecture
Description	AP-4 complex subunit mu-1 (Adapter-related protein complex 4 mu-1 subunit) (Mu subunit of AP-4) (AP-4 adapter complex mu subunit) (Mu- adaptin-related protein 2) (mu-ARP2) (mu4).

DCP1A_HUMAN
θ value	0.0193708 (rank : 17)	NC score	0.064068 (rank : 22)
Query Neighborhood Hits	115	Target Neighborhood Hits	228	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

EYA3_MOUSE
θ value	0.0330416 (rank : 18)	NC score	0.036151 (rank : 43)
Query Neighborhood Hits	115	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	P97480, P97768	Gene names	Eya3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

MUC7_HUMAN
θ value	0.0330416 (rank : 19)	NC score	0.075374 (rank : 18)
Query Neighborhood Hits	115	Target Neighborhood Hits	538	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

PALB2_MOUSE
θ value	0.0563607 (rank : 20)	NC score	0.078085 (rank : 17)
Query Neighborhood Hits	115	Target Neighborhood Hits	133	Shared Neighborhood Hits	8
SwissProt Accessions	Q3U0P1, Q6NZG9, Q7TMQ4, Q8CEA9	Gene names	Palb2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

BIRC2_HUMAN
θ value	0.0961366 (rank : 21)	NC score	0.026517 (rank : 57)
Query Neighborhood Hits	115	Target Neighborhood Hits	142	Shared Neighborhood Hits	3
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

MKL2_MOUSE
θ value	0.0961366 (rank : 22)	NC score	0.038150 (rank : 39)
Query Neighborhood Hits	115	Target Neighborhood Hits	269	Shared Neighborhood Hits	11
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

TCGAP_HUMAN
θ value	0.125558 (rank : 23)	NC score	0.039066 (rank : 38)
Query Neighborhood Hits	115	Target Neighborhood Hits	872	Shared Neighborhood Hits	29
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

LEUK_MOUSE
θ value	0.163984 (rank : 24)	NC score	0.064483 (rank : 21)
Query Neighborhood Hits	115	Target Neighborhood Hits	147	Shared Neighborhood Hits	13
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

TAOK2_HUMAN
θ value	0.163984 (rank : 25)	NC score	0.004673 (rank : 114)
Query Neighborhood Hits	115	Target Neighborhood Hits	1172	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UL54, O94957, Q6UW73, Q7LC09, Q9NSW2	Gene names	TAOK2, KIAA0881, MAP3K17, PSK, PSK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C).

MUC2_HUMAN
θ value	0.21417 (rank : 26)	NC score	0.028448 (rank : 52)
Query Neighborhood Hits	115	Target Neighborhood Hits	906	Shared Neighborhood Hits	25
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PATZ1_HUMAN
θ value	0.21417 (rank : 27)	NC score	0.002628 (rank : 117)
Query Neighborhood Hits	115	Target Neighborhood Hits	802	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBE1, Q9HBE2, Q9HBE3, Q9P1A9, Q9UDU0, Q9Y529	Gene names	PATZ1, PATZ, RIAZ, ZBTB19, ZNF278, ZSG
Domain Architecture
Description	POZ-, AT hook-, and zinc finger-containing protein 1 (Zinc finger protein 278) (Zinc finger sarcoma gene protein) (BTB-POZ domain zinc finger transcription factor) (Protein kinase A RI-subunit alpha- associated protein) (Zinc finger and BTB domain-containing protein 19).

APBB2_HUMAN
θ value	0.279714 (rank : 28)	NC score	0.040644 (rank : 35)
Query Neighborhood Hits	115	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

NCA11_MOUSE
θ value	0.279714 (rank : 29)	NC score	0.012096 (rank : 100)
Query Neighborhood Hits	115	Target Neighborhood Hits	661	Shared Neighborhood Hits	11
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

MAP1A_HUMAN
θ value	0.365318 (rank : 30)	NC score	0.032791 (rank : 47)
Query Neighborhood Hits	115	Target Neighborhood Hits	1626	Shared Neighborhood Hits	53
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

PCGF2_HUMAN
θ value	0.365318 (rank : 31)	NC score	0.038056 (rank : 41)
Query Neighborhood Hits	115	Target Neighborhood Hits	222	Shared Neighborhood Hits	9
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

PTN4_HUMAN
θ value	0.365318 (rank : 32)	NC score	0.012022 (rank : 101)
Query Neighborhood Hits	115	Target Neighborhood Hits	303	Shared Neighborhood Hits	10
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

RBM12_HUMAN
θ value	0.365318 (rank : 33)	NC score	0.032472 (rank : 48)
Query Neighborhood Hits	115	Target Neighborhood Hits	298	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

CSPG5_HUMAN
θ value	0.47712 (rank : 34)	NC score	0.055069 (rank : 26)
Query Neighborhood Hits	115	Target Neighborhood Hits	199	Shared Neighborhood Hits	12
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

MUC1_MOUSE
θ value	0.47712 (rank : 35)	NC score	0.052620 (rank : 27)
Query Neighborhood Hits	115	Target Neighborhood Hits	388	Shared Neighborhood Hits	25
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

CSPG5_MOUSE
θ value	0.62314 (rank : 36)	NC score	0.051905 (rank : 28)
Query Neighborhood Hits	115	Target Neighborhood Hits	211	Shared Neighborhood Hits	10
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

HIF1A_HUMAN
θ value	0.62314 (rank : 37)	NC score	0.018980 (rank : 76)
Query Neighborhood Hits	115	Target Neighborhood Hits	118	Shared Neighborhood Hits	9
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

PCGF2_MOUSE
θ value	0.813845 (rank : 38)	NC score	0.034990 (rank : 45)
Query Neighborhood Hits	115	Target Neighborhood Hits	213	Shared Neighborhood Hits	9
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

PININ_HUMAN
θ value	1.06291 (rank : 39)	NC score	0.025515 (rank : 58)
Query Neighborhood Hits	115	Target Neighborhood Hits	753	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

WIRE_MOUSE
θ value	1.06291 (rank : 40)	NC score	0.033588 (rank : 46)
Query Neighborhood Hits	115	Target Neighborhood Hits	310	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

CBP_HUMAN
θ value	1.38821 (rank : 41)	NC score	0.022798 (rank : 64)
Query Neighborhood Hits	115	Target Neighborhood Hits	941	Shared Neighborhood Hits	33
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DSPP_MOUSE
θ value	1.38821 (rank : 42)	NC score	0.048696 (rank : 29)
Query Neighborhood Hits	115	Target Neighborhood Hits	491	Shared Neighborhood Hits	23
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

PTPRZ_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.013119 (rank : 95)
Query Neighborhood Hits	115	Target Neighborhood Hits	255	Shared Neighborhood Hits	16
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

SRCA_MOUSE
θ value	1.38821 (rank : 44)	NC score	0.024925 (rank : 60)
Query Neighborhood Hits	115	Target Neighborhood Hits	212	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

SYNJ1_HUMAN
θ value	1.38821 (rank : 45)	NC score	0.022613 (rank : 65)
Query Neighborhood Hits	115	Target Neighborhood Hits	498	Shared Neighborhood Hits	24
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ANK3_HUMAN
θ value	1.81305 (rank : 46)	NC score	0.009085 (rank : 105)
Query Neighborhood Hits	115	Target Neighborhood Hits	853	Shared Neighborhood Hits	27
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

CE025_HUMAN
θ value	1.81305 (rank : 47)	NC score	0.037677 (rank : 42)
Query Neighborhood Hits	115	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NDZ2, Q6NXN8, Q6ZTU4, Q8IZ15	Gene names	C5orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf25.

CNGB3_HUMAN
θ value	1.81305 (rank : 48)	NC score	0.015484 (rank : 85)
Query Neighborhood Hits	115	Target Neighborhood Hits	206	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

DSPP_HUMAN
θ value	1.81305 (rank : 49)	NC score	0.048057 (rank : 30)
Query Neighborhood Hits	115	Target Neighborhood Hits	645	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

LRCH4_MOUSE
θ value	1.81305 (rank : 50)	NC score	0.017823 (rank : 78)
Query Neighborhood Hits	115	Target Neighborhood Hits	302	Shared Neighborhood Hits	7
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

PRR11_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.031456 (rank : 49)
Query Neighborhood Hits	115	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q96HE9, Q9NUZ7, Q9NXE9	Gene names	PRR11
Domain Architecture	No domain graphic available
Description	Proline-rich protein 11.

RGS3_MOUSE
θ value	1.81305 (rank : 52)	NC score	0.038103 (rank : 40)
Query Neighborhood Hits	115	Target Neighborhood Hits	1621	Shared Neighborhood Hits	67
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SC24B_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.021086 (rank : 70)
Query Neighborhood Hits	115	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	O95487	Gene names	SEC24B
Domain Architecture
Description	Protein transport protein Sec24B (SEC24-related protein B).

SUHW3_MOUSE
θ value	1.81305 (rank : 54)	NC score	0.005217 (rank : 112)
Query Neighborhood Hits	115	Target Neighborhood Hits	697	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P3Y5, Q6ZPM2, Q8K145	Gene names	Suhw3, Kiaa1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 3.

UBP2L_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.028833 (rank : 51)
Query Neighborhood Hits	115	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

ABLM1_MOUSE
θ value	2.36792 (rank : 56)	NC score	0.007411 (rank : 109)
Query Neighborhood Hits	115	Target Neighborhood Hits	356	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K4G5, Q80U86, Q8BIR9, Q8K4G3, Q8K4G4	Gene names	Ablim1, Ablim, Kiaa0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1).

AFF1_HUMAN
θ value	2.36792 (rank : 57)	NC score	0.058327 (rank : 24)
Query Neighborhood Hits	115	Target Neighborhood Hits	506	Shared Neighborhood Hits	25
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

AFF4_MOUSE
θ value	2.36792 (rank : 58)	NC score	0.044001 (rank : 33)
Query Neighborhood Hits	115	Target Neighborhood Hits	581	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

CXX1_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.044859 (rank : 32)
Query Neighborhood Hits	115	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	O15255	Gene names	CXX1
Domain Architecture	No domain graphic available
Description	CAAX box protein 1 (Cerebral protein 5).

MATR3_HUMAN
θ value	2.36792 (rank : 60)	NC score	0.022821 (rank : 63)
Query Neighborhood Hits	115	Target Neighborhood Hits	325	Shared Neighborhood Hits	16
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

NCKX1_HUMAN
θ value	2.36792 (rank : 61)	NC score	0.021411 (rank : 67)
Query Neighborhood Hits	115	Target Neighborhood Hits	223	Shared Neighborhood Hits	11
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

SON_HUMAN
θ value	2.36792 (rank : 62)	NC score	0.040145 (rank : 37)
Query Neighborhood Hits	115	Target Neighborhood Hits	1568	Shared Neighborhood Hits	56
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TAF1C_HUMAN
θ value	2.36792 (rank : 63)	NC score	0.024753 (rank : 61)
Query Neighborhood Hits	115	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q15572, Q59F67, Q8N6V3	Gene names	TAF1C
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor RNA polymerase I subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 110 kDa) (TAFI110).

TARA_HUMAN
θ value	2.36792 (rank : 64)	NC score	0.047224 (rank : 31)
Query Neighborhood Hits	115	Target Neighborhood Hits	1626	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TNR21_MOUSE
θ value	2.36792 (rank : 65)	NC score	0.015927 (rank : 84)
Query Neighborhood Hits	115	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

CJ078_MOUSE
θ value	3.0926 (rank : 66)	NC score	0.027401 (rank : 54)
Query Neighborhood Hits	115	Target Neighborhood Hits	559	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

FYV1_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.012816 (rank : 97)
Query Neighborhood Hits	115	Target Neighborhood Hits	217	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

IWS1_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.030948 (rank : 50)
Query Neighborhood Hits	115	Target Neighborhood Hits	1241	Shared Neighborhood Hits	44
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

K1949_MOUSE
θ value	4.03905 (rank : 69)	NC score	0.020286 (rank : 73)
Query Neighborhood Hits	115	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

MYST3_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.012131 (rank : 99)
Query Neighborhood Hits	115	Target Neighborhood Hits	688	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

PACS1_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.021367 (rank : 69)
Query Neighborhood Hits	115	Target Neighborhood Hits	82	Shared Neighborhood Hits	10
SwissProt Accessions	Q6VY07, Q6PJY6, Q6PKB6, Q7Z590, Q7Z5W4, Q8N8K6, Q96MW0, Q9NW92, Q9ULP5	Gene names	PACS1, KIAA1175
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

RNF12_MOUSE
θ value	4.03905 (rank : 72)	NC score	0.014825 (rank : 89)
Query Neighborhood Hits	115	Target Neighborhood Hits	159	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

SAPS1_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.016975 (rank : 81)
Query Neighborhood Hits	115	Target Neighborhood Hits	144	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

TAOK2_MOUSE
θ value	4.03905 (rank : 74)	NC score	0.001710 (rank : 119)
Query Neighborhood Hits	115	Target Neighborhood Hits	1373	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

AFF2_MOUSE
θ value	5.27518 (rank : 75)	NC score	0.035616 (rank : 44)
Query Neighborhood Hits	115	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

CELR3_MOUSE
θ value	5.27518 (rank : 76)	NC score	0.000366 (rank : 120)
Query Neighborhood Hits	115	Target Neighborhood Hits	687	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

MAP9_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.017179 (rank : 80)
Query Neighborhood Hits	115	Target Neighborhood Hits	518	Shared Neighborhood Hits	14
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

MY116_MOUSE
θ value	5.27518 (rank : 78)	NC score	0.026896 (rank : 55)
Query Neighborhood Hits	115	Target Neighborhood Hits	70	Shared Neighborhood Hits	9
SwissProt Accessions	P17564	Gene names	Myd116
Domain Architecture	No domain graphic available
Description	Myeloid differentiation primary response protein MyD116.

NOLC1_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.020761 (rank : 72)
Query Neighborhood Hits	115	Target Neighborhood Hits	452	Shared Neighborhood Hits	21
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

RAPH1_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.020230 (rank : 74)
Query Neighborhood Hits	115	Target Neighborhood Hits	593	Shared Neighborhood Hits	26
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

RFX1_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.017509 (rank : 79)
Query Neighborhood Hits	115	Target Neighborhood Hits	181	Shared Neighborhood Hits	7
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

SYRM_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.014301 (rank : 91)
Query Neighborhood Hits	115	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T160, Q96FU5, Q9H8K8	Gene names	RARSL, RARS2
Domain Architecture	No domain graphic available
Description	Probable arginyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.19) (Arginine--tRNA ligase) (ArgRS) (Arginyl-tRNA synthetase-like).

TAU_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.026659 (rank : 56)
Query Neighborhood Hits	115	Target Neighborhood Hits	502	Shared Neighborhood Hits	27
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TCGAP_MOUSE
θ value	5.27518 (rank : 84)	NC score	0.028273 (rank : 53)
Query Neighborhood Hits	115	Target Neighborhood Hits	409	Shared Neighborhood Hits	17
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TM131_MOUSE
θ value	5.27518 (rank : 85)	NC score	0.021474 (rank : 66)
Query Neighborhood Hits	115	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	O70472	Gene names	Tmem131, D1Bwg0491e, Rw1
Domain Architecture	No domain graphic available
Description	Transmembrane protein 131 (Protein RW1).

USP9Y_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.007207 (rank : 110)
Query Neighborhood Hits	115	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

3BP1_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.014881 (rank : 88)
Query Neighborhood Hits	115	Target Neighborhood Hits	376	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

AFF4_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.042463 (rank : 34)
Query Neighborhood Hits	115	Target Neighborhood Hits	611	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

ANKS1_MOUSE
θ value	6.88961 (rank : 89)	NC score	0.003937 (rank : 115)
Query Neighborhood Hits	115	Target Neighborhood Hits	453	Shared Neighborhood Hits	3
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

AP3B2_HUMAN
θ value	6.88961 (rank : 90)	NC score	0.009282 (rank : 104)
Query Neighborhood Hits	115	Target Neighborhood Hits	246	Shared Neighborhood Hits	11
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

CPSF7_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.014030 (rank : 92)
Query Neighborhood Hits	115	Target Neighborhood Hits	123	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BTV2, Q3TNF1, Q8BKE7, Q8CFS8	Gene names	Cpsf7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7.

DEN1A_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.012772 (rank : 98)
Query Neighborhood Hits	115	Target Neighborhood Hits	178	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

DIAP2_MOUSE
θ value	6.88961 (rank : 93)	NC score	0.007907 (rank : 108)
Query Neighborhood Hits	115	Target Neighborhood Hits	260	Shared Neighborhood Hits	7
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

EM55_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.004875 (rank : 113)
Query Neighborhood Hits	115	Target Neighborhood Hits	221	Shared Neighborhood Hits	3
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

HXA3_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.002334 (rank : 118)
Query Neighborhood Hits	115	Target Neighborhood Hits	535	Shared Neighborhood Hits	7
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

MDM2_MOUSE
θ value	6.88961 (rank : 96)	NC score	0.013513 (rank : 93)
Query Neighborhood Hits	115	Target Neighborhood Hits	77	Shared Neighborhood Hits	7
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

MRIP_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.016665 (rank : 83)
Query Neighborhood Hits	115	Target Neighborhood Hits	578	Shared Neighborhood Hits	8
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

NCOR2_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.014888 (rank : 87)
Query Neighborhood Hits	115	Target Neighborhood Hits	870	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

OXRP_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.008224 (rank : 106)
Query Neighborhood Hits	115	Target Neighborhood Hits	544	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

PER2_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.010926 (rank : 102)
Query Neighborhood Hits	115	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

PHF3_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.023437 (rank : 62)
Query Neighborhood Hits	115	Target Neighborhood Hits	419	Shared Neighborhood Hits	13
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

SOS2_HUMAN
θ value	6.88961 (rank : 102)	NC score	0.008123 (rank : 107)
Query Neighborhood Hits	115	Target Neighborhood Hits	193	Shared Neighborhood Hits	6
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

ZN207_HUMAN
θ value	6.88961 (rank : 103)	NC score	0.021377 (rank : 68)
Query Neighborhood Hits	115	Target Neighborhood Hits	326	Shared Neighborhood Hits	6
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

ZN414_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.009462 (rank : 103)
Query Neighborhood Hits	115	Target Neighborhood Hits	548	Shared Neighborhood Hits	8
SwissProt Accessions	Q96IQ9	Gene names	ZNF414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

ATS14_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.003276 (rank : 116)
Query Neighborhood Hits	115	Target Neighborhood Hits	382	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

BIN1_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.015055 (rank : 86)
Query Neighborhood Hits	115	Target Neighborhood Hits	335	Shared Neighborhood Hits	19
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

CC054_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.013254 (rank : 94)
Query Neighborhood Hits	115	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EL1	Gene names	C3orf54
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf54.

CN155_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.025341 (rank : 59)
Query Neighborhood Hits	115	Target Neighborhood Hits	385	Shared Neighborhood Hits	18
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

K2027_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.019469 (rank : 75)
Query Neighborhood Hits	115	Target Neighborhood Hits	194	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

KCNH7_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.005416 (rank : 111)
Query Neighborhood Hits	115	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

PDZD2_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.018665 (rank : 77)
Query Neighborhood Hits	115	Target Neighborhood Hits	772	Shared Neighborhood Hits	32
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PININ_MOUSE
θ value	8.99809 (rank : 112)	NC score	0.020924 (rank : 71)
Query Neighborhood Hits	115	Target Neighborhood Hits	777	Shared Neighborhood Hits	20
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

SGIP1_HUMAN
θ value	8.99809 (rank : 113)	NC score	0.014404 (rank : 90)
Query Neighborhood Hits	115	Target Neighborhood Hits	198	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

TB182_HUMAN
θ value	8.99809 (rank : 114)	NC score	0.016936 (rank : 82)
Query Neighborhood Hits	115	Target Neighborhood Hits	414	Shared Neighborhood Hits	16
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

TCF19_MOUSE
θ value	8.99809 (rank : 115)	NC score	0.012891 (rank : 96)
Query Neighborhood Hits	115	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q99KJ5, Q8BPA3, Q9CT93	Gene names	Tcf19, Sc1
Domain Architecture
Description	Transcription factor 19-like protein (SC1 protein homolog).

AP3M1_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.193346 (rank : 13)
Query Neighborhood Hits	115	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2T2	Gene names	AP3M1
Domain Architecture
Description	AP-3 complex subunit mu-1 (Adapter-related protein complex 3 mu-1 subunit) (Mu-adaptin 3A) (AP-3 adapter complex mu3A subunit).

AP3M1_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.193214 (rank : 14)
Query Neighborhood Hits	115	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JKC8, Q5BKQ6	Gene names	Ap3m1
Domain Architecture
Description	AP-3 complex subunit mu-1 (Adapter-related protein complex 3 mu-1 subunit) (Mu-adaptin 3A) (AP-3 adapter complex mu3A subunit).

AP3M2_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.191147 (rank : 16)
Query Neighborhood Hits	115	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	P53677	Gene names	AP3M2
Domain Architecture
Description	AP-3 complex subunit mu-2 (Adapter-related protein complex 3 mu-2 subunit) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Clathrin assembly protein assembly protein complex 1 medium chain homolog 2) (P47B).

AP3M2_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.192339 (rank : 15)
Query Neighborhood Hits	115	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R2R9, Q3UYJ3, Q923G7	Gene names	Ap3m2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit mu-2 (Adapter-related protein complex 3 mu-2 subunit) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Clathrin assembly protein assembly protein complex 1 medium chain homolog 2) (P47B) (m3B).

AP4M1_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.264709 (rank : 12)
Query Neighborhood Hits	115	Target Neighborhood Hits	23	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKC7	Gene names	Ap4m1
Domain Architecture
Description	AP-4 complex subunit mu-1 (Adapter-related protein complex 4 mu-1 subunit) (Mu subunit of AP-4) (AP-4 adapter complex mu subunit) (Mu- adaptin-related protein 2) (mu-ARP2) (mu4).

Hits sorted by NC score

STON2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	115	Target Neighborhood Hits	115	Shared Neighborhood Hits	115
SwissProt Accessions	Q8WXE9, Q6NT47, Q96RI7, Q96RU6	Gene names	STON2, STN2, STNB
Domain Architecture
Description	Stonin-2 (Stoned B).

STON2_MOUSE
NC score	0.973763 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	115	Target Neighborhood Hits	75	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BZ60	Gene names	Ston2, Stn2, Stnb
Domain Architecture
Description	Stonin-2 (Stoned B).

STON1_HUMAN
NC score	0.906721 (rank : 3)	θ value	2.70778e-113 (rank : 4)
Query Neighborhood Hits	115	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6Q2, Q96JE3, Q9BYX3	Gene names	STON1, SALF, SBLF, STN1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

STON1_MOUSE
NC score	0.904887 (rank : 4)	θ value	1.58745e-113 (rank : 3)
Query Neighborhood Hits	115	Target Neighborhood Hits	50	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CDJ8, Q8CDL8, Q9D5T3	Gene names	Ston1, Salf, Sblf, Stn1
Domain Architecture
Description	Stonin-1 (Stoned B-like factor).

AP2M1_HUMAN
NC score	0.469648 (rank : 5)	θ value	1.09485e-13 (rank : 5)
Query Neighborhood Hits	115	Target Neighborhood Hits	33	Shared Neighborhood Hits	11
SwissProt Accessions	Q96CW1, P20172, P53679	Gene names	AP2M1, CLAPM1, KIAA0109
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit mu-1 (Adaptin mu-1) (AP-2 mu-2 chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Plasma membrane adaptor AP-2 50 kDa protein) (HA2 50 kDa subunit) (Clathrin assembly protein complex 2 medium chain).

AP2M1_MOUSE
NC score	0.469648 (rank : 6)	θ value	1.09485e-13 (rank : 6)
Query Neighborhood Hits	115	Target Neighborhood Hits	33	Shared Neighborhood Hits	11
SwissProt Accessions	P84091, P20172, P53679	Gene names	Ap2m1, Clapm1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit mu-1 (Adaptin mu-1) (AP-2 mu-2 chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Plasma membrane adaptor AP-2 50 kDa protein) (Clathrin assembly protein complex 2 medium chain).

AP1M1_HUMAN
NC score	0.460841 (rank : 7)	θ value	1.42992e-13 (rank : 7)
Query Neighborhood Hits	115	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BXS5	Gene names	AP1M1, CLTNM
Domain Architecture
Description	AP-1 complex subunit mu-1 (Adaptor-related protein complex 1 mu-1 subunit) (Mu-adaptin 1) (Adaptor protein complex AP-1 mu-1 subunit) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 1) (AP-mu chain family member mu1A) (Clathrin coat assembly protein AP47) (Clathrin coat- associated protein AP47).

AP1M1_MOUSE
NC score	0.458140 (rank : 8)	θ value	3.18553e-13 (rank : 8)
Query Neighborhood Hits	115	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	P35585	Gene names	Ap1m1, Cltnm
Domain Architecture
Description	AP-1 complex subunit mu-1 (Adaptor-related protein complex 1 mu-1 subunit) (Mu-adaptin 1) (Adaptor protein complex AP-1 mu-1 subunit) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 1) (AP-mu chain family member mu1A) (Clathrin coat assembly protein AP47) (Clathrin coat- associated protein AP47).

AP1M2_HUMAN
NC score	0.448017 (rank : 9)	θ value	5.43371e-13 (rank : 9)
Query Neighborhood Hits	115	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y6Q5, Q9BSI8	Gene names	AP1M2
Domain Architecture
Description	AP-1 complex subunit mu-2 (Adaptor-related protein complex 1 mu-2 subunit) (Mu-adaptin 2) (Adaptor protein complex AP-1 mu-2 subunit) (Golgi adaptor HA1/AP1 adaptin mu-2 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 2) (AP-mu chain family member mu1B).

AP1M2_MOUSE
NC score	0.447466 (rank : 10)	θ value	9.26847e-13 (rank : 10)
Query Neighborhood Hits	115	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	Q9WVP1, Q99LA4, Q9CWP7	Gene names	Ap1m2
Domain Architecture
Description	AP-1 complex subunit mu-2 (Adaptor-related protein complex 1 mu-2 subunit) (Mu-adaptin 2) (Adaptor protein complex AP-1 mu-2 subunit) (Golgi adaptor HA1/AP1 adaptin mu-2 subunit) (Clathrin assembly protein assembly protein complex 1 medium chain 2) (AP-mu chain family member mu1B).

AP4M1_HUMAN
NC score	0.304589 (rank : 11)	θ value	0.0113563 (rank : 16)
Query Neighborhood Hits	115	Target Neighborhood Hits	27	Shared Neighborhood Hits	11
SwissProt Accessions	O00189, Q9UHK9	Gene names	AP4M1, MUARP2
Domain Architecture
Description	AP-4 complex subunit mu-1 (Adapter-related protein complex 4 mu-1 subunit) (Mu subunit of AP-4) (AP-4 adapter complex mu subunit) (Mu- adaptin-related protein 2) (mu-ARP2) (mu4).

AP4M1_MOUSE
NC score	0.264709 (rank : 12)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	115	Target Neighborhood Hits	23	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKC7	Gene names	Ap4m1
Domain Architecture
Description	AP-4 complex subunit mu-1 (Adapter-related protein complex 4 mu-1 subunit) (Mu subunit of AP-4) (AP-4 adapter complex mu subunit) (Mu- adaptin-related protein 2) (mu-ARP2) (mu4).

AP3M1_HUMAN
NC score	0.193346 (rank : 13)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	115	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y2T2	Gene names	AP3M1
Domain Architecture
Description	AP-3 complex subunit mu-1 (Adapter-related protein complex 3 mu-1 subunit) (Mu-adaptin 3A) (AP-3 adapter complex mu3A subunit).

AP3M1_MOUSE
NC score	0.193214 (rank : 14)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	115	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q9JKC8, Q5BKQ6	Gene names	Ap3m1
Domain Architecture
Description	AP-3 complex subunit mu-1 (Adapter-related protein complex 3 mu-1 subunit) (Mu-adaptin 3A) (AP-3 adapter complex mu3A subunit).

AP3M2_MOUSE
NC score	0.192339 (rank : 15)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	115	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q8R2R9, Q3UYJ3, Q923G7	Gene names	Ap3m2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit mu-2 (Adapter-related protein complex 3 mu-2 subunit) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Clathrin assembly protein assembly protein complex 1 medium chain homolog 2) (P47B) (m3B).

AP3M2_HUMAN
NC score	0.191147 (rank : 16)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	115	Target Neighborhood Hits	32	Shared Neighborhood Hits	9
SwissProt Accessions	P53677	Gene names	AP3M2
Domain Architecture
Description	AP-3 complex subunit mu-2 (Adapter-related protein complex 3 mu-2 subunit) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Clathrin assembly protein assembly protein complex 1 medium chain homolog 2) (P47B).

PALB2_MOUSE
NC score	0.078085 (rank : 17)	θ value	0.0563607 (rank : 20)
Query Neighborhood Hits	115	Target Neighborhood Hits	133	Shared Neighborhood Hits	8
SwissProt Accessions	Q3U0P1, Q6NZG9, Q7TMQ4, Q8CEA9	Gene names	Palb2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

MUC7_HUMAN
NC score	0.075374 (rank : 18)	θ value	0.0330416 (rank : 19)
Query Neighborhood Hits	115	Target Neighborhood Hits	538	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TAX7	Gene names	MUC7, MG2
Domain Architecture	No domain graphic available
Description	Mucin-7 precursor (MUC-7) (Salivary mucin-7) (Apo-MG2).

AFF1_MOUSE
NC score	0.072474 (rank : 19)	θ value	0.00665767 (rank : 15)
Query Neighborhood Hits	115	Target Neighborhood Hits	351	Shared Neighborhood Hits	18
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

LMO7_HUMAN
NC score	0.070160 (rank : 20)	θ value	0.00228821 (rank : 12)
Query Neighborhood Hits	115	Target Neighborhood Hits	507	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WWI1, O15462, O95346, Q9UKC1, Q9UQM5, Q9Y6A7	Gene names	LMO7, FBX20, FBXO20, KIAA0858
Domain Architecture
Description	LIM domain only protein 7 (LOMP) (F-box only protein 20).

LEUK_MOUSE
NC score	0.064483 (rank : 21)	θ value	0.163984 (rank : 24)
Query Neighborhood Hits	115	Target Neighborhood Hits	147	Shared Neighborhood Hits	13
SwissProt Accessions	P15702	Gene names	Spn
Domain Architecture	No domain graphic available
Description	Leukosialin precursor (Leukocyte sialoglycoprotein) (Sialophorin) (Ly- 48) (B cell differentiation antigen LP-3) (CD43 antigen).

DCP1A_HUMAN
NC score	0.064068 (rank : 22)	θ value	0.0193708 (rank : 17)
Query Neighborhood Hits	115	Target Neighborhood Hits	228	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NPI6	Gene names	DCP1A, SMIF
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (Smad4-interacting transcriptional co-activator).

SET1A_HUMAN
NC score	0.061615 (rank : 23)	θ value	0.00390308 (rank : 14)
Query Neighborhood Hits	115	Target Neighborhood Hits	690	Shared Neighborhood Hits	26
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

AFF1_HUMAN
NC score	0.058327 (rank : 24)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	115	Target Neighborhood Hits	506	Shared Neighborhood Hits	25
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

SRRM2_HUMAN
NC score	0.055764 (rank : 25)	θ value	0.00298849 (rank : 13)
Query Neighborhood Hits	115	Target Neighborhood Hits	1296	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CSPG5_HUMAN
NC score	0.055069 (rank : 26)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	115	Target Neighborhood Hits	199	Shared Neighborhood Hits	12
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

MUC1_MOUSE
NC score	0.052620 (rank : 27)	θ value	0.47712 (rank : 35)
Query Neighborhood Hits	115	Target Neighborhood Hits	388	Shared Neighborhood Hits	25
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

CSPG5_MOUSE
NC score	0.051905 (rank : 28)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	115	Target Neighborhood Hits	211	Shared Neighborhood Hits	10
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

DSPP_MOUSE
NC score	0.048696 (rank : 29)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	115	Target Neighborhood Hits	491	Shared Neighborhood Hits	23
SwissProt Accessions	P97399, O70567	Gene names	Dspp
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor (Dentin matrix protein 3) (DMP-3) [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

DSPP_HUMAN
NC score	0.048057 (rank : 30)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	115	Target Neighborhood Hits	645	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

TARA_HUMAN
NC score	0.047224 (rank : 31)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	115	Target Neighborhood Hits	1626	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CXX1_HUMAN
NC score	0.044859 (rank : 32)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	115	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	O15255	Gene names	CXX1
Domain Architecture	No domain graphic available
Description	CAAX box protein 1 (Cerebral protein 5).

AFF4_MOUSE
NC score	0.044001 (rank : 33)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	115	Target Neighborhood Hits	581	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

AFF4_HUMAN
NC score	0.042463 (rank : 34)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	115	Target Neighborhood Hits	611	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

APBB2_HUMAN
NC score	0.040644 (rank : 35)	θ value	0.279714 (rank : 28)
Query Neighborhood Hits	115	Target Neighborhood Hits	96	Shared Neighborhood Hits	7
SwissProt Accessions	Q92870, Q8IUI6	Gene names	APBB2, FE65L, FE65L1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 2 (Fe65-like protein).

ECM2_HUMAN
NC score	0.040513 (rank : 36)	θ value	0.000270298 (rank : 11)
Query Neighborhood Hits	115	Target Neighborhood Hits	402	Shared Neighborhood Hits	8
SwissProt Accessions	O94769	Gene names	ECM2
Domain Architecture
Description	Extracellular matrix protein 2 precursor (Matrix glycoprotein SC1/ECM2).

SON_HUMAN
NC score	0.040145 (rank : 37)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	115	Target Neighborhood Hits	1568	Shared Neighborhood Hits	56
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TCGAP_HUMAN
NC score	0.039066 (rank : 38)	θ value	0.125558 (rank : 23)
Query Neighborhood Hits	115	Target Neighborhood Hits	872	Shared Neighborhood Hits	29
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

MKL2_MOUSE
NC score	0.038150 (rank : 39)	θ value	0.0961366 (rank : 22)
Query Neighborhood Hits	115	Target Neighborhood Hits	269	Shared Neighborhood Hits	11
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

RGS3_MOUSE
NC score	0.038103 (rank : 40)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	115	Target Neighborhood Hits	1621	Shared Neighborhood Hits	67
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

PCGF2_HUMAN
NC score	0.038056 (rank : 41)	θ value	0.365318 (rank : 31)
Query Neighborhood Hits	115	Target Neighborhood Hits	222	Shared Neighborhood Hits	9
SwissProt Accessions	P35227	Gene names	PCGF2, MEL18, RNF110, ZNF144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144).

CE025_HUMAN
NC score	0.037677 (rank : 42)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	115	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NDZ2, Q6NXN8, Q6ZTU4, Q8IZ15	Gene names	C5orf25
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C5orf25.

EYA3_MOUSE
NC score	0.036151 (rank : 43)	θ value	0.0330416 (rank : 18)
Query Neighborhood Hits	115	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	P97480, P97768	Gene names	Eya3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

AFF2_MOUSE
NC score	0.035616 (rank : 44)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	115	Target Neighborhood Hits	225	Shared Neighborhood Hits	15
SwissProt Accessions	O55112	Gene names	Aff2, Fmr2, Ox19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (FMR2P) (Protein Ox19).

PCGF2_MOUSE
NC score	0.034990 (rank : 45)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	115	Target Neighborhood Hits	213	Shared Neighborhood Hits	9
SwissProt Accessions	P23798	Gene names	Pcgf2, Mel-18, Mel18, Rnf110, Zfp144, Znf144
Domain Architecture
Description	Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) (Zfp-144).

WIRE_MOUSE
NC score	0.033588 (rank : 46)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	115	Target Neighborhood Hits	310	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PEV3	Gene names	Wire
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein).

MAP1A_HUMAN
NC score	0.032791 (rank : 47)	θ value	0.365318 (rank : 30)
Query Neighborhood Hits	115	Target Neighborhood Hits	1626	Shared Neighborhood Hits	53
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

RBM12_HUMAN
NC score	0.032472 (rank : 48)	θ value	0.365318 (rank : 33)
Query Neighborhood Hits	115	Target Neighborhood Hits	298	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

PRR11_HUMAN
NC score	0.031456 (rank : 49)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	115	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	Q96HE9, Q9NUZ7, Q9NXE9	Gene names	PRR11
Domain Architecture	No domain graphic available
Description	Proline-rich protein 11.

IWS1_HUMAN
NC score	0.030948 (rank : 50)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	115	Target Neighborhood Hits	1241	Shared Neighborhood Hits	44
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

UBP2L_HUMAN
NC score	0.028833 (rank : 51)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	115	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

MUC2_HUMAN
NC score	0.028448 (rank : 52)	θ value	0.21417 (rank : 26)
Query Neighborhood Hits	115	Target Neighborhood Hits	906	Shared Neighborhood Hits	25
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

TCGAP_MOUSE
NC score	0.028273 (rank : 53)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	115	Target Neighborhood Hits	409	Shared Neighborhood Hits	17
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

CJ078_MOUSE
NC score	0.027401 (rank : 54)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	115	Target Neighborhood Hits	559	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BP27, Q3UIQ6, Q8R3W0, Q9CRT7, Q9D0D7, Q9D116, Q9D4W4	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf78 homolog.

MY116_MOUSE
NC score	0.026896 (rank : 55)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	115	Target Neighborhood Hits	70	Shared Neighborhood Hits	9
SwissProt Accessions	P17564	Gene names	Myd116
Domain Architecture	No domain graphic available
Description	Myeloid differentiation primary response protein MyD116.

TAU_MOUSE
NC score	0.026659 (rank : 56)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	115	Target Neighborhood Hits	502	Shared Neighborhood Hits	27
SwissProt Accessions	P10637, P10638, Q60684, Q60685, Q60686, Q62286	Gene names	Mapt, Mtapt, Tau
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

BIRC2_HUMAN
NC score	0.026517 (rank : 57)	θ value	0.0961366 (rank : 21)
Query Neighborhood Hits	115	Target Neighborhood Hits	142	Shared Neighborhood Hits	3
SwissProt Accessions	Q13490, Q16516, Q4TTG0	Gene names	BIRC2, API1, IAP2, MIHB
Domain Architecture
Description	Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF signaling complex protein 2) (IAP homolog B).

PININ_HUMAN
NC score	0.025515 (rank : 58)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	115	Target Neighborhood Hits	753	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

CN155_HUMAN
NC score	0.025341 (rank : 59)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	115	Target Neighborhood Hits	385	Shared Neighborhood Hits	18
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

SRCA_MOUSE
NC score	0.024925 (rank : 60)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	115	Target Neighborhood Hits	212	Shared Neighborhood Hits	8
SwissProt Accessions	Q7TQ48, Q8BS43	Gene names	Srl, Sar
Domain Architecture	No domain graphic available
Description	Sarcalumenin precursor.

TAF1C_HUMAN
NC score	0.024753 (rank : 61)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	115	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q15572, Q59F67, Q8N6V3	Gene names	TAF1C
Domain Architecture	No domain graphic available
Description	TATA box-binding protein-associated factor RNA polymerase I subunit C (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (TBP-associated factor RNA polymerase I 110 kDa) (TAFI110).

PHF3_HUMAN
NC score	0.023437 (rank : 62)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	115	Target Neighborhood Hits	419	Shared Neighborhood Hits	13
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

MATR3_HUMAN
NC score	0.022821 (rank : 63)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	115	Target Neighborhood Hits	325	Shared Neighborhood Hits	16
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

CBP_HUMAN
NC score	0.022798 (rank : 64)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	115	Target Neighborhood Hits	941	Shared Neighborhood Hits	33
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SYNJ1_HUMAN
NC score	0.022613 (rank : 65)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	115	Target Neighborhood Hits	498	Shared Neighborhood Hits	24
SwissProt Accessions	O43426, O43425, O94984	Gene names	SYNJ1, KIAA0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TM131_MOUSE
NC score	0.021474 (rank : 66)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	115	Target Neighborhood Hits	156	Shared Neighborhood Hits	8
SwissProt Accessions	O70472	Gene names	Tmem131, D1Bwg0491e, Rw1
Domain Architecture	No domain graphic available
Description	Transmembrane protein 131 (Protein RW1).

NCKX1_HUMAN
NC score	0.021411 (rank : 67)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	115	Target Neighborhood Hits	223	Shared Neighborhood Hits	11
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

ZN207_HUMAN
NC score	0.021377 (rank : 68)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	115	Target Neighborhood Hits	326	Shared Neighborhood Hits	6
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

PACS1_HUMAN
NC score	0.021367 (rank : 69)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	115	Target Neighborhood Hits	82	Shared Neighborhood Hits	10
SwissProt Accessions	Q6VY07, Q6PJY6, Q6PKB6, Q7Z590, Q7Z5W4, Q8N8K6, Q96MW0, Q9NW92, Q9ULP5	Gene names	PACS1, KIAA1175
Domain Architecture	No domain graphic available
Description	Phosphofurin acidic cluster sorting protein 1 (PACS-1).

SC24B_HUMAN
NC score	0.021086 (rank : 70)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	115	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	O95487	Gene names	SEC24B
Domain Architecture
Description	Protein transport protein Sec24B (SEC24-related protein B).

PININ_MOUSE
NC score	0.020924 (rank : 71)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	115	Target Neighborhood Hits	777	Shared Neighborhood Hits	20
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

NOLC1_HUMAN
NC score	0.020761 (rank : 72)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	115	Target Neighborhood Hits	452	Shared Neighborhood Hits	21
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

K1949_MOUSE
NC score	0.020286 (rank : 73)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	115	Target Neighborhood Hits	134	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BQ30, Q3UDS6, Q8CEY9, Q8R3D8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1949 homolog.

RAPH1_HUMAN
NC score	0.020230 (rank : 74)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	115	Target Neighborhood Hits	593	Shared Neighborhood Hits	26
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

K2027_HUMAN
NC score	0.019469 (rank : 75)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	115	Target Neighborhood Hits	194	Shared Neighborhood Hits	14
SwissProt Accessions	Q6ZVF9, Q8IVE4	Gene names	KIAA2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

HIF1A_HUMAN
NC score	0.018980 (rank : 76)	θ value	0.62314 (rank : 37)
Query Neighborhood Hits	115	Target Neighborhood Hits	118	Shared Neighborhood Hits	9
SwissProt Accessions	Q16665, Q96PT9, Q9UPB1	Gene names	HIF1A
Domain Architecture
Description	Hypoxia-inducible factor 1 alpha (HIF-1 alpha) (HIF1 alpha) (ARNT- interacting protein) (Member of PAS protein 1) (MOP1).

PDZD2_HUMAN
NC score	0.018665 (rank : 77)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	115	Target Neighborhood Hits	772	Shared Neighborhood Hits	32
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

LRCH4_MOUSE
NC score	0.017823 (rank : 78)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	115	Target Neighborhood Hits	302	Shared Neighborhood Hits	7
SwissProt Accessions	Q921G6	Gene names	Lrch4
Domain Architecture
Description	Leucine-rich repeats and calponin homology domain-containing protein 4.

RFX1_MOUSE
NC score	0.017509 (rank : 79)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	115	Target Neighborhood Hits	181	Shared Neighborhood Hits	7
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

MAP9_HUMAN
NC score	0.017179 (rank : 80)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	115	Target Neighborhood Hits	518	Shared Neighborhood Hits	14
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

SAPS1_MOUSE
NC score	0.016975 (rank : 81)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	115	Target Neighborhood Hits	144	Shared Neighborhood Hits	17
SwissProt Accessions	Q7TSI3, Q80TJ4	Gene names	Saps1, Kiaa1115
Domain Architecture	No domain graphic available
Description	SAPS domain family member 1.

TB182_HUMAN
NC score	0.016936 (rank : 82)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	115	Target Neighborhood Hits	414	Shared Neighborhood Hits	16
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

MRIP_HUMAN
NC score	0.016665 (rank : 83)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	115	Target Neighborhood Hits	578	Shared Neighborhood Hits	8
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

TNR21_MOUSE
NC score	0.015927 (rank : 84)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	115	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q9EPU5, Q91W77, Q91XH9	Gene names	Tnfrsf21, Dr6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 21 precursor (TNFR- related death receptor 6) (Death receptor 6).

CNGB3_HUMAN
NC score	0.015484 (rank : 85)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	115	Target Neighborhood Hits	206	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NQW8, Q9NRE9	Gene names	CNGB3
Domain Architecture
Description	Cyclic nucleotide-gated cation channel beta 3 (CNG channel beta 3) (Cyclic nucleotide-gated channel beta 3) (Cone photoreceptor cGMP- gated channel subunit beta) (Cyclic nucleotide-gated cation channel modulatory subunit).

BIN1_HUMAN
NC score	0.015055 (rank : 86)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	115	Target Neighborhood Hits	335	Shared Neighborhood Hits	19
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

NCOR2_HUMAN
NC score	0.014888 (rank : 87)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	115	Target Neighborhood Hits	870	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

3BP1_HUMAN
NC score	0.014881 (rank : 88)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	115	Target Neighborhood Hits	376	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RNF12_MOUSE
NC score	0.014825 (rank : 89)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	115	Target Neighborhood Hits	159	Shared Neighborhood Hits	8
SwissProt Accessions	Q9WTV7	Gene names	Rnf12, Rlim
Domain Architecture
Description	RING finger protein 12 (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM).

SGIP1_HUMAN
NC score	0.014404 (rank : 90)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	115	Target Neighborhood Hits	198	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BQI5, Q4LE32, Q5VYE2, Q5VYE3, Q5VYE4, Q68D76, Q6MZY6, Q8IWC2	Gene names	SGIP1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

SYRM_HUMAN
NC score	0.014301 (rank : 91)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	115	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q5T160, Q96FU5, Q9H8K8	Gene names	RARSL, RARS2
Domain Architecture	No domain graphic available
Description	Probable arginyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.19) (Arginine--tRNA ligase) (ArgRS) (Arginyl-tRNA synthetase-like).

CPSF7_MOUSE
NC score	0.014030 (rank : 92)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	115	Target Neighborhood Hits	123	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BTV2, Q3TNF1, Q8BKE7, Q8CFS8	Gene names	Cpsf7
Domain Architecture	No domain graphic available
Description	Cleavage and polyadenylation specificity factor 7.

MDM2_MOUSE
NC score	0.013513 (rank : 93)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	115	Target Neighborhood Hits	77	Shared Neighborhood Hits	7
SwissProt Accessions	P23804, Q61040, Q64330	Gene names	Mdm2
Domain Architecture
Description	Ubiquitin-protein ligase E3 Mdm2 (EC 6.3.2.-) (p53-binding protein Mdm2) (Oncoprotein Mdm2) (Double minute 2 protein).

CC054_HUMAN
NC score	0.013254 (rank : 94)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	115	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EL1	Gene names	C3orf54
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C3orf54.

PTPRZ_HUMAN
NC score	0.013119 (rank : 95)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	115	Target Neighborhood Hits	255	Shared Neighborhood Hits	16
SwissProt Accessions	P23471	Gene names	PTPRZ1, PTPRZ, PTPZ
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase zeta precursor (EC 3.1.3.48) (R-PTP-zeta).

TCF19_MOUSE
NC score	0.012891 (rank : 96)	θ value	8.99809 (rank : 115)
Query Neighborhood Hits	115	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	Q99KJ5, Q8BPA3, Q9CT93	Gene names	Tcf19, Sc1
Domain Architecture
Description	Transcription factor 19-like protein (SC1 protein homolog).

FYV1_HUMAN
NC score	0.012816 (rank : 97)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	115	Target Neighborhood Hits	217	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y2I7, Q8NB67	Gene names	PIP5K3, KIAA0981, PIKFYVE
Domain Architecture
Description	FYVE finger-containing phosphoinositide kinase (EC 2.7.1.68) (1- phosphatidylinositol-4-phosphate 5-kinase) (Phosphatidylinositol-3- phosphate 5-kinase type III) (PIP5K) (PtdIns(4)P-5-kinase) (PIKfyve) (p235).

DEN1A_MOUSE
NC score	0.012772 (rank : 98)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	115	Target Neighborhood Hits	178	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

MYST3_MOUSE
NC score	0.012131 (rank : 99)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	115	Target Neighborhood Hits	688	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

NCA11_MOUSE
NC score	0.012096 (rank : 100)	θ value	0.279714 (rank : 29)
Query Neighborhood Hits	115	Target Neighborhood Hits	661	Shared Neighborhood Hits	11
SwissProt Accessions	P13595, Q61949	Gene names	Ncam1, Ncam
Domain Architecture
Description	Neural cell adhesion molecule 1, 180 kDa isoform precursor (N-CAM 180) (NCAM-180).

PTN4_HUMAN
NC score	0.012022 (rank : 101)	θ value	0.365318 (rank : 32)
Query Neighborhood Hits	115	Target Neighborhood Hits	303	Shared Neighborhood Hits	10
SwissProt Accessions	P29074	Gene names	PTPN4
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 4 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG).

PER2_HUMAN
NC score	0.010926 (rank : 102)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	115	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	O15055	Gene names	PER2, KIAA0347
Domain Architecture
Description	Period circadian protein 2.

ZN414_HUMAN
NC score	0.009462 (rank : 103)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	115	Target Neighborhood Hits	548	Shared Neighborhood Hits	8
SwissProt Accessions	Q96IQ9	Gene names	ZNF414
Domain Architecture	No domain graphic available
Description	Zinc finger protein 414.

AP3B2_HUMAN
NC score	0.009282 (rank : 104)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	115	Target Neighborhood Hits	246	Shared Neighborhood Hits	11
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

ANK3_HUMAN
NC score	0.009085 (rank : 105)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	115	Target Neighborhood Hits	853	Shared Neighborhood Hits	27
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

OXRP_HUMAN
NC score	0.008224 (rank : 106)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	115	Target Neighborhood Hits	544	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

SOS2_HUMAN
NC score	0.008123 (rank : 107)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	115	Target Neighborhood Hits	193	Shared Neighborhood Hits	6
SwissProt Accessions	Q07890, Q15503	Gene names	SOS2
Domain Architecture
Description	Son of sevenless homolog 2 (SOS-2).

DIAP2_MOUSE
NC score	0.007907 (rank : 108)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	115	Target Neighborhood Hits	260	Shared Neighborhood Hits	7
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

ABLM1_MOUSE
NC score	0.007411 (rank : 109)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	115	Target Neighborhood Hits	356	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K4G5, Q80U86, Q8BIR9, Q8K4G3, Q8K4G4	Gene names	Ablim1, Ablim, Kiaa0059
Domain Architecture	No domain graphic available
Description	Actin-binding LIM protein 1 (Actin-binding LIM protein family member 1) (abLIM-1).

USP9Y_HUMAN
NC score	0.007207 (rank : 110)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	115	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	O00507, O14601	Gene names	USP9Y, DFFRY, USP10
Domain Architecture
Description	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (EC 3.1.2.15) (Ubiquitin thioesterase FAF-Y) (Ubiquitin-specific-processing protease FAF-Y) (Deubiquitinating enzyme FAF-Y) (Fat facets protein-related, Y- linked) (Ubiquitin-specific protease 9, Y chromosome).

KCNH7_HUMAN
NC score	0.005416 (rank : 111)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	115	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NS40	Gene names	KCNH7, ERG3
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 7 (Voltage-gated potassium channel subunit Kv11.3) (Ether-a-go-go-related gene potassium channel 3) (HERG-3) (Ether-a-go-go-related protein 3) (Eag- related protein 3).

SUHW3_MOUSE
NC score	0.005217 (rank : 112)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	115	Target Neighborhood Hits	697	Shared Neighborhood Hits	8
SwissProt Accessions	Q6P3Y5, Q6ZPM2, Q8K145	Gene names	Suhw3, Kiaa1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 3.

EM55_MOUSE
NC score	0.004875 (rank : 113)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	115	Target Neighborhood Hits	221	Shared Neighborhood Hits	3
SwissProt Accessions	P70290	Gene names	Mpp1
Domain Architecture
Description	55 kDa erythrocyte membrane protein (p55) (Membrane protein, palmitoylated 1) (Palmitoylated protein p55).

TAOK2_HUMAN
NC score	0.004673 (rank : 114)	θ value	0.163984 (rank : 25)
Query Neighborhood Hits	115	Target Neighborhood Hits	1172	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UL54, O94957, Q6UW73, Q7LC09, Q9NSW2	Gene names	TAOK2, KIAA0881, MAP3K17, PSK, PSK1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2) (Prostate-derived STE20-like kinase 1) (PSK-1) (Kinase from chicken homolog C) (hKFC-C).

ANKS1_MOUSE
NC score	0.003937 (rank : 115)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	115	Target Neighborhood Hits	453	Shared Neighborhood Hits	3
SwissProt Accessions	P59672, Q6ZQG0	Gene names	Anks1a, Anks1, Kiaa0229
Domain Architecture
Description	Ankyrin repeat and SAM domain-containing protein 1A.

ATS14_HUMAN
NC score	0.003276 (rank : 116)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	115	Target Neighborhood Hits	382	Shared Neighborhood Hits	11
SwissProt Accessions	Q8WXS8, Q8TE55, Q8TEY8	Gene names	ADAMTS14
Domain Architecture
Description	ADAMTS-14 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 14) (ADAM-TS 14) (ADAM-TS14).

PATZ1_HUMAN
NC score	0.002628 (rank : 117)	θ value	0.21417 (rank : 27)
Query Neighborhood Hits	115	Target Neighborhood Hits	802	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HBE1, Q9HBE2, Q9HBE3, Q9P1A9, Q9UDU0, Q9Y529	Gene names	PATZ1, PATZ, RIAZ, ZBTB19, ZNF278, ZSG
Domain Architecture
Description	POZ-, AT hook-, and zinc finger-containing protein 1 (Zinc finger protein 278) (Zinc finger sarcoma gene protein) (BTB-POZ domain zinc finger transcription factor) (Protein kinase A RI-subunit alpha- associated protein) (Zinc finger and BTB domain-containing protein 19).

HXA3_HUMAN
NC score	0.002334 (rank : 118)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	115	Target Neighborhood Hits	535	Shared Neighborhood Hits	7
SwissProt Accessions	O43365	Gene names	HOXA3, HOX1E
Domain Architecture
Description	Homeobox protein Hox-A3 (Hox-1E).

TAOK2_MOUSE
NC score	0.001710 (rank : 119)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	115	Target Neighborhood Hits	1373	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZQ29, Q7TSS8	Gene names	Taok2, Kiaa0881
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2).

CELR3_MOUSE
NC score	0.000366 (rank : 120)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	115	Target Neighborhood Hits	687	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.