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Network neighborhood for query Sequence : HS90A_HUMAN

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HS90A_HUMAN
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HS90A_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	144	Target Neighborhood Hits	144	Shared Neighborhood Hits	144
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

HS90A_MOUSE
θ value	0 (rank : 2)	NC score	0.987110 (rank : 2)
Query Neighborhood Hits	144	Target Neighborhood Hits	155	Shared Neighborhood Hits	104
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

HS90B_HUMAN
θ value	0 (rank : 3)	NC score	0.977168 (rank : 4)
Query Neighborhood Hits	144	Target Neighborhood Hits	98	Shared Neighborhood Hits	49
SwissProt Accessions	P08238, Q5T9W7, Q9NQW0	Gene names	HSP90AB1, HSP90B, HSPC2, HSPCB
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (HSP 90).

HS90B_MOUSE
θ value	0 (rank : 4)	NC score	0.977869 (rank : 3)
Query Neighborhood Hits	144	Target Neighborhood Hits	98	Shared Neighborhood Hits	50
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

ENPL_HUMAN
θ value	1.34698e-104 (rank : 5)	NC score	0.929734 (rank : 6)
Query Neighborhood Hits	144	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	P14625, Q96A97	Gene names	HSP90B1, TRA1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (gp96 homolog) (Tumor rejection antigen 1).

ENPL_MOUSE
θ value	1.14028e-103 (rank : 6)	NC score	0.929758 (rank : 5)
Query Neighborhood Hits	144	Target Neighborhood Hits	78	Shared Neighborhood Hits	25
SwissProt Accessions	P08113, P11427	Gene names	Hsp90b1, Tra-1, Tra1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (ERP99) (Polymorphic tumor rejection antigen 1) (Tumor rejection antigen gp96).

TRAP1_MOUSE
θ value	5.02714e-51 (rank : 7)	NC score	0.855933 (rank : 8)
Query Neighborhood Hits	144	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CQN1, Q542I4	Gene names	Trap1
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

TRAP1_HUMAN
θ value	4.25575e-50 (rank : 8)	NC score	0.857572 (rank : 7)
Query Neighborhood Hits	144	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q12931, O43642, O75235, Q9UHL5	Gene names	TRAP1, HSP75
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

SEC63_HUMAN
θ value	0.00665767 (rank : 9)	NC score	0.118079 (rank : 10)
Query Neighborhood Hits	144	Target Neighborhood Hits	586	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_MOUSE
θ value	0.00869519 (rank : 10)	NC score	0.112749 (rank : 11)
Query Neighborhood Hits	144	Target Neighborhood Hits	601	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

SMC2_MOUSE
θ value	0.0113563 (rank : 11)	NC score	0.067925 (rank : 15)
Query Neighborhood Hits	144	Target Neighborhood Hits	1131	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

TSH1_MOUSE
θ value	0.0193708 (rank : 12)	NC score	0.042810 (rank : 47)
Query Neighborhood Hits	144	Target Neighborhood Hits	675	Shared Neighborhood Hits	16
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

TCRG1_HUMAN
θ value	0.0252991 (rank : 13)	NC score	0.086941 (rank : 13)
Query Neighborhood Hits	144	Target Neighborhood Hits	929	Shared Neighborhood Hits	65
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	0.0252991 (rank : 14)	NC score	0.086331 (rank : 14)
Query Neighborhood Hits	144	Target Neighborhood Hits	947	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

HSF2B_HUMAN
θ value	0.0563607 (rank : 15)	NC score	0.154664 (rank : 9)
Query Neighborhood Hits	144	Target Neighborhood Hits	104	Shared Neighborhood Hits	22
SwissProt Accessions	O75031	Gene names	HSF2BP
Domain Architecture	No domain graphic available
Description	Heat shock factor 2-binding protein.

GOGA4_MOUSE
θ value	0.0736092 (rank : 16)	NC score	0.052233 (rank : 32)
Query Neighborhood Hits	144	Target Neighborhood Hits	1939	Shared Neighborhood Hits	91
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

RAD50_HUMAN
θ value	0.125558 (rank : 17)	NC score	0.054081 (rank : 25)
Query Neighborhood Hits	144	Target Neighborhood Hits	1317	Shared Neighborhood Hits	71
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

SYCP1_MOUSE
θ value	0.125558 (rank : 18)	NC score	0.055884 (rank : 23)
Query Neighborhood Hits	144	Target Neighborhood Hits	1456	Shared Neighborhood Hits	75
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

NIN_MOUSE
θ value	0.163984 (rank : 19)	NC score	0.050635 (rank : 38)
Query Neighborhood Hits	144	Target Neighborhood Hits	1376	Shared Neighborhood Hits	70
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

PEG3_MOUSE
θ value	0.163984 (rank : 20)	NC score	0.011017 (rank : 133)
Query Neighborhood Hits	144	Target Neighborhood Hits	1101	Shared Neighborhood Hits	28
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

PRI1_MOUSE
θ value	0.163984 (rank : 21)	NC score	0.091543 (rank : 12)
Query Neighborhood Hits	144	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	P20664	Gene names	Prim1
Domain Architecture
Description	DNA primase small subunit (EC 2.7.7.-) (DNA primase 49 kDa subunit) (p49).

SMC2_HUMAN
θ value	0.163984 (rank : 22)	NC score	0.063463 (rank : 16)
Query Neighborhood Hits	144	Target Neighborhood Hits	1405	Shared Neighborhood Hits	77
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

LEO1_MOUSE
θ value	0.279714 (rank : 23)	NC score	0.061701 (rank : 17)
Query Neighborhood Hits	144	Target Neighborhood Hits	946	Shared Neighborhood Hits	54
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

MINT_MOUSE
θ value	0.279714 (rank : 24)	NC score	0.037809 (rank : 74)
Query Neighborhood Hits	144	Target Neighborhood Hits	1514	Shared Neighborhood Hits	46
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SMC1A_HUMAN
θ value	0.279714 (rank : 25)	NC score	0.059969 (rank : 19)
Query Neighborhood Hits	144	Target Neighborhood Hits	1346	Shared Neighborhood Hits	75
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	0.279714 (rank : 26)	NC score	0.058637 (rank : 20)
Query Neighborhood Hits	144	Target Neighborhood Hits	1384	Shared Neighborhood Hits	74
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

LARP1_HUMAN
θ value	0.365318 (rank : 27)	NC score	0.050037 (rank : 39)
Query Neighborhood Hits	144	Target Neighborhood Hits	242	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

OXRP_HUMAN
θ value	0.365318 (rank : 28)	NC score	0.036938 (rank : 78)
Query Neighborhood Hits	144	Target Neighborhood Hits	544	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

UBP8_HUMAN
θ value	0.365318 (rank : 29)	NC score	0.033611 (rank : 87)
Query Neighborhood Hits	144	Target Neighborhood Hits	751	Shared Neighborhood Hits	63
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

E41L2_HUMAN
θ value	0.47712 (rank : 30)	NC score	0.022524 (rank : 111)
Query Neighborhood Hits	144	Target Neighborhood Hits	287	Shared Neighborhood Hits	36
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

LEO1_HUMAN
θ value	0.47712 (rank : 31)	NC score	0.060048 (rank : 18)
Query Neighborhood Hits	144	Target Neighborhood Hits	958	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MINT_HUMAN
θ value	0.47712 (rank : 32)	NC score	0.047903 (rank : 41)
Query Neighborhood Hits	144	Target Neighborhood Hits	1291	Shared Neighborhood Hits	56
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

OXSR1_MOUSE
θ value	0.47712 (rank : 33)	NC score	0.011698 (rank : 131)
Query Neighborhood Hits	144	Target Neighborhood Hits	865	Shared Neighborhood Hits	12
SwissProt Accessions	Q6P9R2, Q8BVZ9, Q8C0B9	Gene names	Oxsr1, Osr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

SDPR_HUMAN
θ value	0.47712 (rank : 34)	NC score	0.056757 (rank : 22)
Query Neighborhood Hits	144	Target Neighborhood Hits	337	Shared Neighborhood Hits	35
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

AN30A_HUMAN
θ value	0.62314 (rank : 35)	NC score	0.038107 (rank : 71)
Query Neighborhood Hits	144	Target Neighborhood Hits	1119	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

C8AP2_HUMAN
θ value	0.62314 (rank : 36)	NC score	0.038497 (rank : 68)
Query Neighborhood Hits	144	Target Neighborhood Hits	548	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

CKAP2_HUMAN
θ value	0.62314 (rank : 37)	NC score	0.034681 (rank : 83)
Query Neighborhood Hits	144	Target Neighborhood Hits	116	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

OXSR1_HUMAN
θ value	0.62314 (rank : 38)	NC score	0.010467 (rank : 137)
Query Neighborhood Hits	144	Target Neighborhood Hits	874	Shared Neighborhood Hits	11
SwissProt Accessions	O95747, Q3LR53, Q7Z501, Q9UPQ1	Gene names	OXSR1, KIAA1101, OSR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

TRIPB_HUMAN
θ value	0.62314 (rank : 39)	NC score	0.055323 (rank : 24)
Query Neighborhood Hits	144	Target Neighborhood Hits	1587	Shared Neighborhood Hits	69
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

ZN318_MOUSE
θ value	0.62314 (rank : 40)	NC score	0.053141 (rank : 28)
Query Neighborhood Hits	144	Target Neighborhood Hits	642	Shared Neighborhood Hits	50
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

CCD46_HUMAN
θ value	0.813845 (rank : 41)	NC score	0.042792 (rank : 48)
Query Neighborhood Hits	144	Target Neighborhood Hits	1430	Shared Neighborhood Hits	70
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

ST1E1_HUMAN
θ value	0.813845 (rank : 42)	NC score	0.025040 (rank : 104)
Query Neighborhood Hits	144	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	P49888, Q8N6X5	Gene names	SULT1E1, STE
Domain Architecture
Description	Estrogen sulfotransferase (EC 2.8.2.4) (Sulfotransferase, estrogen- preferring) (EST-1).

CT2NL_HUMAN
θ value	1.06291 (rank : 43)	NC score	0.042369 (rank : 50)
Query Neighborhood Hits	144	Target Neighborhood Hits	1059	Shared Neighborhood Hits	58
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CUL1_HUMAN
θ value	1.06291 (rank : 44)	NC score	0.025690 (rank : 101)
Query Neighborhood Hits	144	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q13616, O60719, Q8IYW1	Gene names	CUL1
Domain Architecture
Description	Cullin-1 (CUL-1).

CUL1_MOUSE
θ value	1.06291 (rank : 45)	NC score	0.025688 (rank : 102)
Query Neighborhood Hits	144	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WTX6, Q9WUI7	Gene names	Cul1
Domain Architecture
Description	Cullin-1 (CUL-1).

LRRF2_HUMAN
θ value	1.06291 (rank : 46)	NC score	0.039722 (rank : 64)
Query Neighborhood Hits	144	Target Neighborhood Hits	791	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

MPP8_HUMAN
θ value	1.06291 (rank : 47)	NC score	0.041881 (rank : 52)
Query Neighborhood Hits	144	Target Neighborhood Hits	948	Shared Neighborhood Hits	63
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

RAD50_MOUSE
θ value	1.06291 (rank : 48)	NC score	0.047093 (rank : 42)
Query Neighborhood Hits	144	Target Neighborhood Hits	1366	Shared Neighborhood Hits	63
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RB6I2_HUMAN
θ value	1.06291 (rank : 49)	NC score	0.038344 (rank : 70)
Query Neighborhood Hits	144	Target Neighborhood Hits	1584	Shared Neighborhood Hits	74
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

SDPR_MOUSE
θ value	1.06291 (rank : 50)	NC score	0.051722 (rank : 36)
Query Neighborhood Hits	144	Target Neighborhood Hits	485	Shared Neighborhood Hits	45
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

TTC1_HUMAN
θ value	1.06291 (rank : 51)	NC score	0.024343 (rank : 108)
Query Neighborhood Hits	144	Target Neighborhood Hits	417	Shared Neighborhood Hits	25
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

ACHA9_HUMAN
θ value	1.38821 (rank : 52)	NC score	0.009582 (rank : 139)
Query Neighborhood Hits	144	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGM1, Q4W5A2, Q9NYV2	Gene names	CHRNA9, NACHRA9
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-9 precursor (Nicotinic acetylcholine receptor subunit alpha 9) (NACHR alpha 9).

MYH13_HUMAN
θ value	1.38821 (rank : 53)	NC score	0.030554 (rank : 93)
Query Neighborhood Hits	144	Target Neighborhood Hits	1504	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

NUDC_MOUSE
θ value	1.38821 (rank : 54)	NC score	0.045269 (rank : 43)
Query Neighborhood Hits	144	Target Neighborhood Hits	42	Shared Neighborhood Hits	12
SwissProt Accessions	O35685, Q3UJS7	Gene names	Nudc
Domain Architecture	No domain graphic available
Description	Nuclear migration protein nudC (Nuclear distribution protein C homolog) (Silica-induced gene 92 protein) (SIG-92).

PHF20_MOUSE
θ value	1.38821 (rank : 55)	NC score	0.037045 (rank : 77)
Query Neighborhood Hits	144	Target Neighborhood Hits	513	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

TR150_HUMAN
θ value	1.38821 (rank : 56)	NC score	0.053636 (rank : 26)
Query Neighborhood Hits	144	Target Neighborhood Hits	313	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

TR150_MOUSE
θ value	1.38821 (rank : 57)	NC score	0.052464 (rank : 31)
Query Neighborhood Hits	144	Target Neighborhood Hits	468	Shared Neighborhood Hits	36
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

ANK2_HUMAN
θ value	1.81305 (rank : 58)	NC score	0.011427 (rank : 132)
Query Neighborhood Hits	144	Target Neighborhood Hits	1615	Shared Neighborhood Hits	54
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

ANR11_HUMAN
θ value	1.81305 (rank : 59)	NC score	0.037463 (rank : 75)
Query Neighborhood Hits	144	Target Neighborhood Hits	1289	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

MATR3_HUMAN
θ value	1.81305 (rank : 60)	NC score	0.030855 (rank : 92)
Query Neighborhood Hits	144	Target Neighborhood Hits	325	Shared Neighborhood Hits	25
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

TCAL3_HUMAN
θ value	1.81305 (rank : 61)	NC score	0.040050 (rank : 62)
Query Neighborhood Hits	144	Target Neighborhood Hits	274	Shared Neighborhood Hits	17
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

ARI5B_HUMAN
θ value	2.36792 (rank : 62)	NC score	0.031286 (rank : 90)
Query Neighborhood Hits	144	Target Neighborhood Hits	328	Shared Neighborhood Hits	23
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

BPAEA_MOUSE
θ value	2.36792 (rank : 63)	NC score	0.036180 (rank : 81)
Query Neighborhood Hits	144	Target Neighborhood Hits	1480	Shared Neighborhood Hits	69
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CJ118_HUMAN
θ value	2.36792 (rank : 64)	NC score	0.042391 (rank : 49)
Query Neighborhood Hits	144	Target Neighborhood Hits	937	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

HS105_HUMAN
θ value	2.36792 (rank : 65)	NC score	0.021647 (rank : 112)
Query Neighborhood Hits	144	Target Neighborhood Hits	209	Shared Neighborhood Hits	24
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

MYH3_HUMAN
θ value	2.36792 (rank : 66)	NC score	0.027119 (rank : 97)
Query Neighborhood Hits	144	Target Neighborhood Hits	1660	Shared Neighborhood Hits	74
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

NUDC_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.040283 (rank : 60)
Query Neighborhood Hits	144	Target Neighborhood Hits	48	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y266, Q5QP31, Q5QP35, Q9H0N2, Q9Y2B6	Gene names	NUDC
Domain Architecture	No domain graphic available
Description	Nuclear migration protein nudC (Nuclear distribution protein C homolog).

PITX2_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.011002 (rank : 134)
Query Neighborhood Hits	144	Target Neighborhood Hits	381	Shared Neighborhood Hits	7
SwissProt Accessions	Q99697, O60578, O60579, O60580, Q9BY17	Gene names	PITX2, ARP1, RGS, RIEG, RIEG1
Domain Architecture
Description	Pituitary homeobox 2 (RIEG bicoid-related homeobox transcription factor) (Solurshin) (ALL1-responsive protein ARP1).

TAF4_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.029823 (rank : 94)
Query Neighborhood Hits	144	Target Neighborhood Hits	687	Shared Neighborhood Hits	26
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

ARHG7_MOUSE
θ value	3.0926 (rank : 70)	NC score	0.008390 (rank : 144)
Query Neighborhood Hits	144	Target Neighborhood Hits	396	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

CT2NL_MOUSE
θ value	3.0926 (rank : 71)	NC score	0.040482 (rank : 59)
Query Neighborhood Hits	144	Target Neighborhood Hits	902	Shared Neighborhood Hits	55
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

DYH9_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.026758 (rank : 98)
Query Neighborhood Hits	144	Target Neighborhood Hits	291	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

HDGF_MOUSE
θ value	3.0926 (rank : 73)	NC score	0.026226 (rank : 99)
Query Neighborhood Hits	144	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	P51859, Q8BPG7, Q9CYA4, Q9JK87	Gene names	Hdgf, Tdrm1
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF).

NGAP_HUMAN
θ value	3.0926 (rank : 74)	NC score	0.025598 (rank : 103)
Query Neighborhood Hits	144	Target Neighborhood Hits	517	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

NKTR_HUMAN
θ value	3.0926 (rank : 75)	NC score	0.024465 (rank : 107)
Query Neighborhood Hits	144	Target Neighborhood Hits	658	Shared Neighborhood Hits	44
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

TACC3_HUMAN
θ value	3.0926 (rank : 76)	NC score	0.037406 (rank : 76)
Query Neighborhood Hits	144	Target Neighborhood Hits	779	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

TCAL5_HUMAN
θ value	3.0926 (rank : 77)	NC score	0.042141 (rank : 51)
Query Neighborhood Hits	144	Target Neighborhood Hits	806	Shared Neighborhood Hits	42
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

ZBT40_HUMAN
θ value	3.0926 (rank : 78)	NC score	-0.000315 (rank : 151)
Query Neighborhood Hits	144	Target Neighborhood Hits	949	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

CHD3_HUMAN
θ value	4.03905 (rank : 79)	NC score	0.010885 (rank : 135)
Query Neighborhood Hits	144	Target Neighborhood Hits	397	Shared Neighborhood Hits	26
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

IFT74_HUMAN
θ value	4.03905 (rank : 80)	NC score	0.043297 (rank : 46)
Query Neighborhood Hits	144	Target Neighborhood Hits	949	Shared Neighborhood Hits	61
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IWS1_HUMAN
θ value	4.03905 (rank : 81)	NC score	0.028697 (rank : 96)
Query Neighborhood Hits	144	Target Neighborhood Hits	1241	Shared Neighborhood Hits	65
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

KMHN1_HUMAN
θ value	4.03905 (rank : 82)	NC score	0.038564 (rank : 67)
Query Neighborhood Hits	144	Target Neighborhood Hits	950	Shared Neighborhood Hits	58
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

MAP1A_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.048913 (rank : 40)
Query Neighborhood Hits	144	Target Neighborhood Hits	1626	Shared Neighborhood Hits	87
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

REST_HUMAN
θ value	4.03905 (rank : 84)	NC score	0.036198 (rank : 80)
Query Neighborhood Hits	144	Target Neighborhood Hits	1605	Shared Neighborhood Hits	80
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

SURF2_MOUSE
θ value	4.03905 (rank : 85)	NC score	0.036534 (rank : 79)
Query Neighborhood Hits	144	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P09926	Gene names	Surf2, Surf-2
Domain Architecture
Description	Surfeit locus protein 2 (Surf-2).

ANLN_MOUSE
θ value	5.27518 (rank : 86)	NC score	0.038372 (rank : 69)
Query Neighborhood Hits	144	Target Neighborhood Hits	297	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

ANR12_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.039177 (rank : 65)
Query Neighborhood Hits	144	Target Neighborhood Hits	1081	Shared Neighborhood Hits	74
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

AXN2_MOUSE
θ value	5.27518 (rank : 88)	NC score	0.011809 (rank : 129)
Query Neighborhood Hits	144	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

CC47_MOUSE
θ value	5.27518 (rank : 89)	NC score	0.023770 (rank : 109)
Query Neighborhood Hits	144	Target Neighborhood Hits	245	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

CCD21_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.035639 (rank : 82)
Query Neighborhood Hits	144	Target Neighborhood Hits	1228	Shared Neighborhood Hits	66
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CENPE_HUMAN
θ value	5.27518 (rank : 91)	NC score	0.040857 (rank : 56)
Query Neighborhood Hits	144	Target Neighborhood Hits	2060	Shared Neighborhood Hits	89
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CHD9_HUMAN
θ value	5.27518 (rank : 92)	NC score	0.011701 (rank : 130)
Query Neighborhood Hits	144	Target Neighborhood Hits	343	Shared Neighborhood Hits	24
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

GOGA4_HUMAN
θ value	5.27518 (rank : 93)	NC score	0.045058 (rank : 45)
Query Neighborhood Hits	144	Target Neighborhood Hits	2034	Shared Neighborhood Hits	88
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

GOGB1_HUMAN
θ value	5.27518 (rank : 94)	NC score	0.039176 (rank : 66)
Query Neighborhood Hits	144	Target Neighborhood Hits	2297	Shared Neighborhood Hits	89
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

GRP78_HUMAN
θ value	5.27518 (rank : 95)	NC score	0.016462 (rank : 120)
Query Neighborhood Hits	144	Target Neighborhood Hits	218	Shared Neighborhood Hits	27
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

GRP78_MOUSE
θ value	5.27518 (rank : 96)	NC score	0.016397 (rank : 121)
Query Neighborhood Hits	144	Target Neighborhood Hits	216	Shared Neighborhood Hits	26
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

KTN1_HUMAN
θ value	5.27518 (rank : 97)	NC score	0.040611 (rank : 57)
Query Neighborhood Hits	144	Target Neighborhood Hits	1197	Shared Neighborhood Hits	60
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

MPIP3_HUMAN
θ value	5.27518 (rank : 98)	NC score	0.029393 (rank : 95)
Query Neighborhood Hits	144	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	P30307, Q96PL3, Q9H168, Q9H2E8, Q9H2E9, Q9H2F1	Gene names	CDC25C
Domain Architecture
Description	M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C).

NSBP1_MOUSE
θ value	5.27518 (rank : 99)	NC score	0.051671 (rank : 37)
Query Neighborhood Hits	144	Target Neighborhood Hits	681	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

P52K_HUMAN
θ value	5.27518 (rank : 100)	NC score	0.024942 (rank : 105)
Query Neighborhood Hits	144	Target Neighborhood Hits	142	Shared Neighborhood Hits	12
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

PPIG_HUMAN
θ value	5.27518 (rank : 101)	NC score	0.033892 (rank : 86)
Query Neighborhood Hits	144	Target Neighborhood Hits	670	Shared Neighborhood Hits	68
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

TAOK3_HUMAN
θ value	5.27518 (rank : 102)	NC score	0.009292 (rank : 140)
Query Neighborhood Hits	144	Target Neighborhood Hits	1494	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

TUFT1_MOUSE
θ value	5.27518 (rank : 103)	NC score	0.031179 (rank : 91)
Query Neighborhood Hits	144	Target Neighborhood Hits	732	Shared Neighborhood Hits	46
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

AT10A_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.014919 (rank : 123)
Query Neighborhood Hits	144	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	O60312, Q969I4	Gene names	ATP10A, ATP10C, ATPVC, KIAA0566
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase VA (EC 3.6.3.1) (ATPVA) (Aminophospholipid translocase VA).

CCD55_HUMAN
θ value	6.88961 (rank : 105)	NC score	0.032240 (rank : 89)
Query Neighborhood Hits	144	Target Neighborhood Hits	513	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CLGN_MOUSE
θ value	6.88961 (rank : 106)	NC score	0.009016 (rank : 143)
Query Neighborhood Hits	144	Target Neighborhood Hits	142	Shared Neighborhood Hits	12
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

CLSPN_HUMAN
θ value	6.88961 (rank : 107)	NC score	0.040520 (rank : 58)
Query Neighborhood Hits	144	Target Neighborhood Hits	433	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

CS029_HUMAN
θ value	6.88961 (rank : 108)	NC score	0.041496 (rank : 54)
Query Neighborhood Hits	144	Target Neighborhood Hits	329	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

GCC2_MOUSE
θ value	6.88961 (rank : 109)	NC score	0.040097 (rank : 61)
Query Neighborhood Hits	144	Target Neighborhood Hits	1619	Shared Neighborhood Hits	79
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

KIF4A_MOUSE
θ value	6.88961 (rank : 110)	NC score	0.023425 (rank : 110)
Query Neighborhood Hits	144	Target Neighborhood Hits	1033	Shared Neighborhood Hits	60
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

MY18A_MOUSE
θ value	6.88961 (rank : 111)	NC score	0.033471 (rank : 88)
Query Neighborhood Hits	144	Target Neighborhood Hits	1989	Shared Neighborhood Hits	81
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PHF3_HUMAN
θ value	6.88961 (rank : 112)	NC score	0.041070 (rank : 55)
Query Neighborhood Hits	144	Target Neighborhood Hits	419	Shared Neighborhood Hits	40
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

PITX2_MOUSE
θ value	6.88961 (rank : 113)	NC score	0.007773 (rank : 145)
Query Neighborhood Hits	144	Target Neighborhood Hits	383	Shared Neighborhood Hits	9
SwissProt Accessions	P97474, O08646, O70336, P97933, Q9JLA0, Q9QXB8, Q9R1V9, Q9Z141	Gene names	Pitx2, Arp1, Brx1, Otlx2, Ptx2, Rgs
Domain Architecture
Description	Pituitary homeobox 2 (Orthodenticle-like homeobox 2) (Solurshin) (ALL1-responsive protein ARP1) (BRX1 homeoprotein) (Paired-like homeodomain transcription factor Munc 30).

PMS2_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.024599 (rank : 106)
Query Neighborhood Hits	144	Target Neighborhood Hits	131	Shared Neighborhood Hits	11
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

POT15_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.020287 (rank : 113)
Query Neighborhood Hits	144	Target Neighborhood Hits	893	Shared Neighborhood Hits	57
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

RAE1_MOUSE
θ value	6.88961 (rank : 116)	NC score	0.007582 (rank : 146)
Query Neighborhood Hits	144	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXG2, Q80UV8	Gene names	Chm, Rep1
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 1 (Rab escort protein 1) (REP-1) (Choroideraemia protein homolog).

SHOX_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.006568 (rank : 148)
Query Neighborhood Hits	144	Target Neighborhood Hits	363	Shared Neighborhood Hits	7
SwissProt Accessions	O15266, O00412, O00413, O15267	Gene names	SHOX, PHOG
Domain Architecture
Description	Short stature homeobox protein (Short stature homeobox-containing protein) (Pseudoautosomal homeobox-containing osteogenic protein).

STK39_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.006400 (rank : 149)
Query Neighborhood Hits	144	Target Neighborhood Hits	882	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).

STK39_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.006969 (rank : 147)
Query Neighborhood Hits	144	Target Neighborhood Hits	915	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

SYCP1_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.045247 (rank : 44)
Query Neighborhood Hits	144	Target Neighborhood Hits	1313	Shared Neighborhood Hits	76
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYNE1_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.040030 (rank : 63)
Query Neighborhood Hits	144	Target Neighborhood Hits	1484	Shared Neighborhood Hits	69
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

SYNE2_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.034001 (rank : 85)
Query Neighborhood Hits	144	Target Neighborhood Hits	1323	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TEX14_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.014045 (rank : 126)
Query Neighborhood Hits	144	Target Neighborhood Hits	1103	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

VPS41_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.016617 (rank : 119)
Query Neighborhood Hits	144	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	P49754, Q99851, Q99852	Gene names	VPS41
Domain Architecture
Description	Vacuolar protein sorting-associated protein 41 homolog (S53).

VPS41_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.016923 (rank : 118)
Query Neighborhood Hits	144	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q5KU39, Q3TPS1, Q80V99, Q8BKK6, Q8CG01, Q8CJC3	Gene names	Vps41
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 41 homolog (VAM2 homolog) (mVAM2).

ANR26_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.037835 (rank : 72)
Query Neighborhood Hits	144	Target Neighborhood Hits	1614	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

BPAEA_HUMAN
θ value	8.99809 (rank : 127)	NC score	0.034205 (rank : 84)
Query Neighborhood Hits	144	Target Neighborhood Hits	1369	Shared Neighborhood Hits	67
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CHD6_HUMAN
θ value	8.99809 (rank : 128)	NC score	0.010819 (rank : 136)
Query Neighborhood Hits	144	Target Neighborhood Hits	342	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CP135_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.037816 (rank : 73)
Query Neighborhood Hits	144	Target Neighborhood Hits	1290	Shared Neighborhood Hits	67
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

DIAP3_HUMAN
θ value	8.99809 (rank : 130)	NC score	0.010172 (rank : 138)
Query Neighborhood Hits	144	Target Neighborhood Hits	209	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

DYH11_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.026151 (rank : 100)
Query Neighborhood Hits	144	Target Neighborhood Hits	234	Shared Neighborhood Hits	28
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).

E2F6_MOUSE
θ value	8.99809 (rank : 132)	NC score	0.014352 (rank : 125)
Query Neighborhood Hits	144	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	O54917	Gene names	E2f6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA).

FIBP_MOUSE
θ value	8.99809 (rank : 133)	NC score	0.020262 (rank : 114)
Query Neighborhood Hits	144	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JI19	Gene names	Fibp
Domain Architecture
Description	Acidic fibroblast growth factor intracellular-binding protein (aFGF intracellular-binding protein) (FGF-1 intracellular-binding protein).

LACTB_HUMAN
θ value	8.99809 (rank : 134)	NC score	0.018182 (rank : 116)
Query Neighborhood Hits	144	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	P83111, P83096	Gene names	LACTB
Domain Architecture
Description	Serine beta-lactamase-like protein LACTB.

MRE11_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.012736 (rank : 128)
Query Neighborhood Hits	144	Target Neighborhood Hits	95	Shared Neighborhood Hits	9
SwissProt Accessions	P49959, O43475	Gene names	MRE11A, HNGS1, MRE11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A).

MYRIP_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.013257 (rank : 127)
Query Neighborhood Hits	144	Target Neighborhood Hits	269	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

OSBL8_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.009138 (rank : 141)
Query Neighborhood Hits	144	Target Neighborhood Hits	289	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

PDCL2_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.009110 (rank : 142)
Query Neighborhood Hits	144	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N4E4	Gene names	PDCL2
Domain Architecture	No domain graphic available
Description	Phosducin-like protein 2.

ROCK1_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.015961 (rank : 122)
Query Neighborhood Hits	144	Target Neighborhood Hits	2000	Shared Neighborhood Hits	69
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

RPGR_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.014761 (rank : 124)
Query Neighborhood Hits	144	Target Neighborhood Hits	279	Shared Neighborhood Hits	29
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

SIL1_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.019907 (rank : 115)
Query Neighborhood Hits	144	Target Neighborhood Hits	68	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H173, Q8N2L3	Gene names	SIL1
Domain Architecture	No domain graphic available
Description	Nucleotide exchange factor SIL1 precursor (BiP-associated protein) (BAP).

SPTB1_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.017945 (rank : 117)
Query Neighborhood Hits	144	Target Neighborhood Hits	543	Shared Neighborhood Hits	42
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

TXND2_MOUSE
θ value	8.99809 (rank : 143)	NC score	0.041714 (rank : 53)
Query Neighborhood Hits	144	Target Neighborhood Hits	828	Shared Neighborhood Hits	59
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ZA2G_MOUSE
θ value	8.99809 (rank : 144)	NC score	0.006070 (rank : 150)
Query Neighborhood Hits	144	Target Neighborhood Hits	174	Shared Neighborhood Hits	5
SwissProt Accessions	Q64726	Gene names	Azgp1
Domain Architecture
Description	Zinc-alpha-2-glycoprotein precursor (Zn-alpha-2-glycoprotein) (Zn- alpha-2-GP).

CALD1_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.052117 (rank : 33)
Query Neighborhood Hits	144	Target Neighborhood Hits	959	Shared Neighborhood Hits	88
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

IF2P_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.052045 (rank : 34)
Query Neighborhood Hits	144	Target Neighborhood Hits	889	Shared Neighborhood Hits	93
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

NSBP1_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.052649 (rank : 29)
Query Neighborhood Hits	144	Target Neighborhood Hits	251	Shared Neighborhood Hits	52
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

RBM25_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.052549 (rank : 30)
Query Neighborhood Hits	144	Target Neighborhood Hits	682	Shared Neighborhood Hits	76
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

RENT2_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.051864 (rank : 35)
Query Neighborhood Hits	144	Target Neighborhood Hits	618	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

SFR12_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.053333 (rank : 27)
Query Neighborhood Hits	144	Target Neighborhood Hits	553	Shared Neighborhood Hits	69
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

TRDN_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.057476 (rank : 21)
Query Neighborhood Hits	144	Target Neighborhood Hits	542	Shared Neighborhood Hits	79
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

Hits sorted by NC score

HS90A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	144	Target Neighborhood Hits	144	Shared Neighborhood Hits	144
SwissProt Accessions	P07900, Q2PP14, Q9BVQ5	Gene names	HSP90AA1, HSP90A, HSPC1, HSPCA
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (NY-REN-38 antigen).

HS90A_MOUSE
NC score	0.987110 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	144	Target Neighborhood Hits	155	Shared Neighborhood Hits	104
SwissProt Accessions	P07901	Gene names	Hsp90aa1, Hsp86, Hsp86-1, Hspca
Domain Architecture
Description	Heat shock protein HSP 90-alpha (HSP 86) (Tumor-specific transplantation 86 kDa antigen) (TSTA).

HS90B_MOUSE
NC score	0.977869 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	144	Target Neighborhood Hits	98	Shared Neighborhood Hits	50
SwissProt Accessions	P11499, O89078	Gene names	Hsp90ab1, Hsp84, Hsp84-1, Hspcb
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (Tumor-specific transplantation 84 kDa antigen) (TSTA).

HS90B_HUMAN
NC score	0.977168 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	144	Target Neighborhood Hits	98	Shared Neighborhood Hits	49
SwissProt Accessions	P08238, Q5T9W7, Q9NQW0	Gene names	HSP90AB1, HSP90B, HSPC2, HSPCB
Domain Architecture
Description	Heat shock protein HSP 90-beta (HSP 84) (HSP 90).

ENPL_MOUSE
NC score	0.929758 (rank : 5)	θ value	1.14028e-103 (rank : 6)
Query Neighborhood Hits	144	Target Neighborhood Hits	78	Shared Neighborhood Hits	25
SwissProt Accessions	P08113, P11427	Gene names	Hsp90b1, Tra-1, Tra1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (ERP99) (Polymorphic tumor rejection antigen 1) (Tumor rejection antigen gp96).

ENPL_HUMAN
NC score	0.929734 (rank : 6)	θ value	1.34698e-104 (rank : 5)
Query Neighborhood Hits	144	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	P14625, Q96A97	Gene names	HSP90B1, TRA1
Domain Architecture
Description	Endoplasmin precursor (Heat shock protein 90 kDa beta member 1) (94 kDa glucose-regulated protein) (GRP94) (gp96 homolog) (Tumor rejection antigen 1).

TRAP1_HUMAN
NC score	0.857572 (rank : 7)	θ value	4.25575e-50 (rank : 8)
Query Neighborhood Hits	144	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q12931, O43642, O75235, Q9UHL5	Gene names	TRAP1, HSP75
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

TRAP1_MOUSE
NC score	0.855933 (rank : 8)	θ value	5.02714e-51 (rank : 7)
Query Neighborhood Hits	144	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CQN1, Q542I4	Gene names	Trap1
Domain Architecture
Description	Heat shock protein 75 kDa, mitochondrial precursor (HSP 75) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) (TNFR- associated protein 1).

HSF2B_HUMAN
NC score	0.154664 (rank : 9)	θ value	0.0563607 (rank : 15)
Query Neighborhood Hits	144	Target Neighborhood Hits	104	Shared Neighborhood Hits	22
SwissProt Accessions	O75031	Gene names	HSF2BP
Domain Architecture	No domain graphic available
Description	Heat shock factor 2-binding protein.

SEC63_HUMAN
NC score	0.118079 (rank : 10)	θ value	0.00665767 (rank : 9)
Query Neighborhood Hits	144	Target Neighborhood Hits	586	Shared Neighborhood Hits	36
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_MOUSE
NC score	0.112749 (rank : 11)	θ value	0.00869519 (rank : 10)
Query Neighborhood Hits	144	Target Neighborhood Hits	601	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

PRI1_MOUSE
NC score	0.091543 (rank : 12)	θ value	0.163984 (rank : 21)
Query Neighborhood Hits	144	Target Neighborhood Hits	16	Shared Neighborhood Hits	6
SwissProt Accessions	P20664	Gene names	Prim1
Domain Architecture
Description	DNA primase small subunit (EC 2.7.7.-) (DNA primase 49 kDa subunit) (p49).

TCRG1_HUMAN
NC score	0.086941 (rank : 13)	θ value	0.0252991 (rank : 13)
Query Neighborhood Hits	144	Target Neighborhood Hits	929	Shared Neighborhood Hits	65
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
NC score	0.086331 (rank : 14)	θ value	0.0252991 (rank : 14)
Query Neighborhood Hits	144	Target Neighborhood Hits	947	Shared Neighborhood Hits	64
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

SMC2_MOUSE
NC score	0.067925 (rank : 15)	θ value	0.0113563 (rank : 11)
Query Neighborhood Hits	144	Target Neighborhood Hits	1131	Shared Neighborhood Hits	66
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SMC2_HUMAN
NC score	0.063463 (rank : 16)	θ value	0.163984 (rank : 22)
Query Neighborhood Hits	144	Target Neighborhood Hits	1405	Shared Neighborhood Hits	77
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

LEO1_MOUSE
NC score	0.061701 (rank : 17)	θ value	0.279714 (rank : 23)
Query Neighborhood Hits	144	Target Neighborhood Hits	946	Shared Neighborhood Hits	54
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LEO1_HUMAN
NC score	0.060048 (rank : 18)	θ value	0.47712 (rank : 31)
Query Neighborhood Hits	144	Target Neighborhood Hits	958	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

SMC1A_HUMAN
NC score	0.059969 (rank : 19)	θ value	0.279714 (rank : 25)
Query Neighborhood Hits	144	Target Neighborhood Hits	1346	Shared Neighborhood Hits	75
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
NC score	0.058637 (rank : 20)	θ value	0.279714 (rank : 26)
Query Neighborhood Hits	144	Target Neighborhood Hits	1384	Shared Neighborhood Hits	74
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

TRDN_HUMAN
NC score	0.057476 (rank : 21)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	144	Target Neighborhood Hits	542	Shared Neighborhood Hits	79
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

SDPR_HUMAN
NC score	0.056757 (rank : 22)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	144	Target Neighborhood Hits	337	Shared Neighborhood Hits	35
SwissProt Accessions	O95810	Gene names	SDPR
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein) (PS-p68).

SYCP1_MOUSE
NC score	0.055884 (rank : 23)	θ value	0.125558 (rank : 18)
Query Neighborhood Hits	144	Target Neighborhood Hits	1456	Shared Neighborhood Hits	75
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TRIPB_HUMAN
NC score	0.055323 (rank : 24)	θ value	0.62314 (rank : 39)
Query Neighborhood Hits	144	Target Neighborhood Hits	1587	Shared Neighborhood Hits	69
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

RAD50_HUMAN
NC score	0.054081 (rank : 25)	θ value	0.125558 (rank : 17)
Query Neighborhood Hits	144	Target Neighborhood Hits	1317	Shared Neighborhood Hits	71
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

TR150_HUMAN
NC score	0.053636 (rank : 26)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	144	Target Neighborhood Hits	313	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

SFR12_HUMAN
NC score	0.053333 (rank : 27)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	144	Target Neighborhood Hits	553	Shared Neighborhood Hits	69
SwissProt Accessions	Q8WXA9, Q86X37	Gene names	SFRS12, SRRP86
Domain Architecture
Description	Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich- splicing regulatory protein 86) (SRrp86) (Splicing regulatory protein 508) (SRrp508).

ZN318_MOUSE
NC score	0.053141 (rank : 28)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	144	Target Neighborhood Hits	642	Shared Neighborhood Hits	50
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

NSBP1_HUMAN
NC score	0.052649 (rank : 29)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	144	Target Neighborhood Hits	251	Shared Neighborhood Hits	52
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

RBM25_HUMAN
NC score	0.052549 (rank : 30)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	144	Target Neighborhood Hits	682	Shared Neighborhood Hits	76
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

TR150_MOUSE
NC score	0.052464 (rank : 31)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	144	Target Neighborhood Hits	468	Shared Neighborhood Hits	36
SwissProt Accessions	Q569Z6	Gene names	Thrap3, Trap150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

GOGA4_MOUSE
NC score	0.052233 (rank : 32)	θ value	0.0736092 (rank : 16)
Query Neighborhood Hits	144	Target Neighborhood Hits	1939	Shared Neighborhood Hits	91
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

CALD1_HUMAN
NC score	0.052117 (rank : 33)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	144	Target Neighborhood Hits	959	Shared Neighborhood Hits	88
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

IF2P_HUMAN
NC score	0.052045 (rank : 34)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	144	Target Neighborhood Hits	889	Shared Neighborhood Hits	93
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

RENT2_HUMAN
NC score	0.051864 (rank : 35)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	144	Target Neighborhood Hits	618	Shared Neighborhood Hits	79
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

SDPR_MOUSE
NC score	0.051722 (rank : 36)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	144	Target Neighborhood Hits	485	Shared Neighborhood Hits	45
SwissProt Accessions	Q63918, Q3V1P6, Q78EC3, Q8CBT4	Gene names	Sdpr, Sdr
Domain Architecture	No domain graphic available
Description	Serum deprivation-response protein (Phosphatidylserine-binding protein).

NSBP1_MOUSE
NC score	0.051671 (rank : 37)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	144	Target Neighborhood Hits	681	Shared Neighborhood Hits	65
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

NIN_MOUSE
NC score	0.050635 (rank : 38)	θ value	0.163984 (rank : 19)
Query Neighborhood Hits	144	Target Neighborhood Hits	1376	Shared Neighborhood Hits	70
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

LARP1_HUMAN
NC score	0.050037 (rank : 39)	θ value	0.365318 (rank : 27)
Query Neighborhood Hits	144	Target Neighborhood Hits	242	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PKG0, O94836, Q8N4M2, Q8NB73, Q9UFD7	Gene names	LARP1, KIAA0731, LARP
Domain Architecture	No domain graphic available
Description	La-related protein 1 (La ribonucleoprotein domain family member 1).

MAP1A_HUMAN
NC score	0.048913 (rank : 40)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	144	Target Neighborhood Hits	1626	Shared Neighborhood Hits	87
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MINT_HUMAN
NC score	0.047903 (rank : 41)	θ value	0.47712 (rank : 32)
Query Neighborhood Hits	144	Target Neighborhood Hits	1291	Shared Neighborhood Hits	56
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

RAD50_MOUSE
NC score	0.047093 (rank : 42)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	144	Target Neighborhood Hits	1366	Shared Neighborhood Hits	63
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

NUDC_MOUSE
NC score	0.045269 (rank : 43)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	144	Target Neighborhood Hits	42	Shared Neighborhood Hits	12
SwissProt Accessions	O35685, Q3UJS7	Gene names	Nudc
Domain Architecture	No domain graphic available
Description	Nuclear migration protein nudC (Nuclear distribution protein C homolog) (Silica-induced gene 92 protein) (SIG-92).

SYCP1_HUMAN
NC score	0.045247 (rank : 44)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	144	Target Neighborhood Hits	1313	Shared Neighborhood Hits	76
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

GOGA4_HUMAN
NC score	0.045058 (rank : 45)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	144	Target Neighborhood Hits	2034	Shared Neighborhood Hits	88
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

IFT74_HUMAN
NC score	0.043297 (rank : 46)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	144	Target Neighborhood Hits	949	Shared Neighborhood Hits	61
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

TSH1_MOUSE
NC score	0.042810 (rank : 47)	θ value	0.0193708 (rank : 12)
Query Neighborhood Hits	144	Target Neighborhood Hits	675	Shared Neighborhood Hits	16
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

CCD46_HUMAN
NC score	0.042792 (rank : 48)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	144	Target Neighborhood Hits	1430	Shared Neighborhood Hits	70
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CJ118_HUMAN
NC score	0.042391 (rank : 49)	θ value	2.36792 (rank : 64)
Query Neighborhood Hits	144	Target Neighborhood Hits	937	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

CT2NL_HUMAN
NC score	0.042369 (rank : 50)	θ value	1.06291 (rank : 43)
Query Neighborhood Hits	144	Target Neighborhood Hits	1059	Shared Neighborhood Hits	58
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

TCAL5_HUMAN
NC score	0.042141 (rank : 51)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	144	Target Neighborhood Hits	806	Shared Neighborhood Hits	42
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

MPP8_HUMAN
NC score	0.041881 (rank : 52)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	144	Target Neighborhood Hits	948	Shared Neighborhood Hits	63
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

TXND2_MOUSE
NC score	0.041714 (rank : 53)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	144	Target Neighborhood Hits	828	Shared Neighborhood Hits	59
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

CS029_HUMAN
NC score	0.041496 (rank : 54)	θ value	6.88961 (rank : 108)
Query Neighborhood Hits	144	Target Neighborhood Hits	329	Shared Neighborhood Hits	31
SwissProt Accessions	Q8WUQ7, O75229, Q7LE08, Q9BTA6, Q9Y5A4	Gene names	C19orf29
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf29 (NY-REN-24 antigen).

PHF3_HUMAN
NC score	0.041070 (rank : 55)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	144	Target Neighborhood Hits	419	Shared Neighborhood Hits	40
SwissProt Accessions	Q92576, Q5T1T6, Q9NQ16, Q9UI45	Gene names	PHF3, KIAA0244
Domain Architecture
Description	PHD finger protein 3.

CENPE_HUMAN
NC score	0.040857 (rank : 56)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	144	Target Neighborhood Hits	2060	Shared Neighborhood Hits	89
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

KTN1_HUMAN
NC score	0.040611 (rank : 57)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	144	Target Neighborhood Hits	1197	Shared Neighborhood Hits	60
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

CLSPN_HUMAN
NC score	0.040520 (rank : 58)	θ value	6.88961 (rank : 107)
Query Neighborhood Hits	144	Target Neighborhood Hits	433	Shared Neighborhood Hits	60
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

CT2NL_MOUSE
NC score	0.040482 (rank : 59)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	144	Target Neighborhood Hits	902	Shared Neighborhood Hits	55
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

NUDC_HUMAN
NC score	0.040283 (rank : 60)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	144	Target Neighborhood Hits	48	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y266, Q5QP31, Q5QP35, Q9H0N2, Q9Y2B6	Gene names	NUDC
Domain Architecture	No domain graphic available
Description	Nuclear migration protein nudC (Nuclear distribution protein C homolog).

GCC2_MOUSE
NC score	0.040097 (rank : 61)	θ value	6.88961 (rank : 109)
Query Neighborhood Hits	144	Target Neighborhood Hits	1619	Shared Neighborhood Hits	79
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

TCAL3_HUMAN
NC score	0.040050 (rank : 62)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	144	Target Neighborhood Hits	274	Shared Neighborhood Hits	17
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

SYNE1_HUMAN
NC score	0.040030 (rank : 63)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	144	Target Neighborhood Hits	1484	Shared Neighborhood Hits	69
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

LRRF2_HUMAN
NC score	0.039722 (rank : 64)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	144	Target Neighborhood Hits	791	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

ANR12_HUMAN
NC score	0.039177 (rank : 65)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	144	Target Neighborhood Hits	1081	Shared Neighborhood Hits	74
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

GOGB1_HUMAN
NC score	0.039176 (rank : 66)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	144	Target Neighborhood Hits	2297	Shared Neighborhood Hits	89
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

KMHN1_HUMAN
NC score	0.038564 (rank : 67)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	144	Target Neighborhood Hits	950	Shared Neighborhood Hits	58
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

C8AP2_HUMAN
NC score	0.038497 (rank : 68)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	144	Target Neighborhood Hits	548	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UKL3, Q6PH76, Q7LCQ7, Q86YD9, Q9NUQ4, Q9NZV9, Q9P2N1, Q9Y563	Gene names	CASP8AP2, FLASH, KIAA1315, RIP25
Domain Architecture	No domain graphic available
Description	CASP8-associated protein 2 (FLICE-associated huge protein).

ANLN_MOUSE
NC score	0.038372 (rank : 69)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	144	Target Neighborhood Hits	297	Shared Neighborhood Hits	27
SwissProt Accessions	Q8K298, Q8BL79, Q8BLB3, Q8K2N0, Q9CUY0	Gene names	Anln
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

RB6I2_HUMAN
NC score	0.038344 (rank : 70)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	144	Target Neighborhood Hits	1584	Shared Neighborhood Hits	74
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

AN30A_HUMAN
NC score	0.038107 (rank : 71)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	144	Target Neighborhood Hits	1119	Shared Neighborhood Hits	64
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ANR26_HUMAN
NC score	0.037835 (rank : 72)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	144	Target Neighborhood Hits	1614	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CP135_HUMAN
NC score	0.037816 (rank : 73)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	144	Target Neighborhood Hits	1290	Shared Neighborhood Hits	67
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

MINT_MOUSE
NC score	0.037809 (rank : 74)	θ value	0.279714 (rank : 24)
Query Neighborhood Hits	144	Target Neighborhood Hits	1514	Shared Neighborhood Hits	46
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

ANR11_HUMAN
NC score	0.037463 (rank : 75)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	144	Target Neighborhood Hits	1289	Shared Neighborhood Hits	76
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

TACC3_HUMAN
NC score	0.037406 (rank : 76)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	144	Target Neighborhood Hits	779	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

PHF20_MOUSE
NC score	0.037045 (rank : 77)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	144	Target Neighborhood Hits	513	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

OXRP_HUMAN
NC score	0.036938 (rank : 78)	θ value	0.365318 (rank : 28)
Query Neighborhood Hits	144	Target Neighborhood Hits	544	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

SURF2_MOUSE
NC score	0.036534 (rank : 79)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	144	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	P09926	Gene names	Surf2, Surf-2
Domain Architecture
Description	Surfeit locus protein 2 (Surf-2).

REST_HUMAN
NC score	0.036198 (rank : 80)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	144	Target Neighborhood Hits	1605	Shared Neighborhood Hits	80
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

BPAEA_MOUSE
NC score	0.036180 (rank : 81)	θ value	2.36792 (rank : 63)
Query Neighborhood Hits	144	Target Neighborhood Hits	1480	Shared Neighborhood Hits	69
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCD21_HUMAN
NC score	0.035639 (rank : 82)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	144	Target Neighborhood Hits	1228	Shared Neighborhood Hits	66
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CKAP2_HUMAN
NC score	0.034681 (rank : 83)	θ value	0.62314 (rank : 37)
Query Neighborhood Hits	144	Target Neighborhood Hits	116	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WWK9, Q3KRA5, Q5VXB4, Q8IWV5, Q8IWV6, Q96FH9, Q9H012, Q9H0D0, Q9H988, Q9HC49, Q9NVG4	Gene names	CKAP2, LB1, TMAP
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2 (Tumor-associated microtubule- associated protein) (CTCL tumor antigen se20-10).

BPAEA_HUMAN
NC score	0.034205 (rank : 84)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	144	Target Neighborhood Hits	1369	Shared Neighborhood Hits	67
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

SYNE2_HUMAN
NC score	0.034001 (rank : 85)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	144	Target Neighborhood Hits	1323	Shared Neighborhood Hits	64
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

PPIG_HUMAN
NC score	0.033892 (rank : 86)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	144	Target Neighborhood Hits	670	Shared Neighborhood Hits	68
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

UBP8_HUMAN
NC score	0.033611 (rank : 87)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	144	Target Neighborhood Hits	751	Shared Neighborhood Hits	63
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

MY18A_MOUSE
NC score	0.033471 (rank : 88)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	144	Target Neighborhood Hits	1989	Shared Neighborhood Hits	81
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CCD55_HUMAN
NC score	0.032240 (rank : 89)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	144	Target Neighborhood Hits	513	Shared Neighborhood Hits	44
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

ARI5B_HUMAN
NC score	0.031286 (rank : 90)	θ value	2.36792 (rank : 62)
Query Neighborhood Hits	144	Target Neighborhood Hits	328	Shared Neighborhood Hits	23
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

TUFT1_MOUSE
NC score	0.031179 (rank : 91)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	144	Target Neighborhood Hits	732	Shared Neighborhood Hits	46
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

MATR3_HUMAN
NC score	0.030855 (rank : 92)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	144	Target Neighborhood Hits	325	Shared Neighborhood Hits	25
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

MYH13_HUMAN
NC score	0.030554 (rank : 93)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	144	Target Neighborhood Hits	1504	Shared Neighborhood Hits	75
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

TAF4_HUMAN
NC score	0.029823 (rank : 94)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	144	Target Neighborhood Hits	687	Shared Neighborhood Hits	26
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

MPIP3_HUMAN
NC score	0.029393 (rank : 95)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	144	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	P30307, Q96PL3, Q9H168, Q9H2E8, Q9H2E9, Q9H2F1	Gene names	CDC25C
Domain Architecture
Description	M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C).

IWS1_HUMAN
NC score	0.028697 (rank : 96)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	144	Target Neighborhood Hits	1241	Shared Neighborhood Hits	65
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

MYH3_HUMAN
NC score	0.027119 (rank : 97)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	144	Target Neighborhood Hits	1660	Shared Neighborhood Hits	74
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

DYH9_HUMAN
NC score	0.026758 (rank : 98)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	144	Target Neighborhood Hits	291	Shared Neighborhood Hits	33
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

HDGF_MOUSE
NC score	0.026226 (rank : 99)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	144	Target Neighborhood Hits	102	Shared Neighborhood Hits	11
SwissProt Accessions	P51859, Q8BPG7, Q9CYA4, Q9JK87	Gene names	Hdgf, Tdrm1
Domain Architecture
Description	Hepatoma-derived growth factor (HDGF).

DYH11_HUMAN
NC score	0.026151 (rank : 100)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	144	Target Neighborhood Hits	234	Shared Neighborhood Hits	28
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).

CUL1_HUMAN
NC score	0.025690 (rank : 101)	θ value	1.06291 (rank : 44)
Query Neighborhood Hits	144	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q13616, O60719, Q8IYW1	Gene names	CUL1
Domain Architecture
Description	Cullin-1 (CUL-1).

CUL1_MOUSE
NC score	0.025688 (rank : 102)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	144	Target Neighborhood Hits	38	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WTX6, Q9WUI7	Gene names	Cul1
Domain Architecture
Description	Cullin-1 (CUL-1).

NGAP_HUMAN
NC score	0.025598 (rank : 103)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	144	Target Neighborhood Hits	517	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UJF2, O95174, Q5TFU9	Gene names	RASAL2, NGAP
Domain Architecture
Description	Ras GTPase-activating protein nGAP (RAS protein activator-like 1).

ST1E1_HUMAN
NC score	0.025040 (rank : 104)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	144	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	P49888, Q8N6X5	Gene names	SULT1E1, STE
Domain Architecture
Description	Estrogen sulfotransferase (EC 2.8.2.4) (Sulfotransferase, estrogen- preferring) (EST-1).

P52K_HUMAN
NC score	0.024942 (rank : 105)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	144	Target Neighborhood Hits	142	Shared Neighborhood Hits	12
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

PMS2_HUMAN
NC score	0.024599 (rank : 106)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	144	Target Neighborhood Hits	131	Shared Neighborhood Hits	11
SwissProt Accessions	P54278	Gene names	PMS2, PMSL2
Domain Architecture
Description	PMS1 protein homolog 2 (DNA mismatch repair protein PMS2).

NKTR_HUMAN
NC score	0.024465 (rank : 107)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	144	Target Neighborhood Hits	658	Shared Neighborhood Hits	44
SwissProt Accessions	P30414	Gene names	NKTR
Domain Architecture
Description	NK-tumor recognition protein (Natural-killer cells cyclophilin-related protein) (NK-TR protein).

TTC1_HUMAN
NC score	0.024343 (rank : 108)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	144	Target Neighborhood Hits	417	Shared Neighborhood Hits	25
SwissProt Accessions	Q99614, Q9BVT3	Gene names	TTC1, TPR1
Domain Architecture
Description	Tetratricopeptide repeat protein 1 (TPR repeat protein 1).

CC47_MOUSE
NC score	0.023770 (rank : 109)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	144	Target Neighborhood Hits	245	Shared Neighborhood Hits	16
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

KIF4A_MOUSE
NC score	0.023425 (rank : 110)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	144	Target Neighborhood Hits	1033	Shared Neighborhood Hits	60
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

E41L2_HUMAN
NC score	0.022524 (rank : 111)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	144	Target Neighborhood Hits	287	Shared Neighborhood Hits	36
SwissProt Accessions	O43491	Gene names	EPB41L2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

HS105_HUMAN
NC score	0.021647 (rank : 112)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	144	Target Neighborhood Hits	209	Shared Neighborhood Hits	24
SwissProt Accessions	Q92598, O95739, Q5TBM6, Q5TBM8, Q9UPC4	Gene names	HSPH1, HSP105, HSP110, KIAA0201
Domain Architecture
Description	Heat-shock protein 105 kDa (Heat shock 110 kDa protein) (Antigen NY- CO-25).

POT15_HUMAN
NC score	0.020287 (rank : 113)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	144	Target Neighborhood Hits	893	Shared Neighborhood Hits	57
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

FIBP_MOUSE
NC score	0.020262 (rank : 114)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	144	Target Neighborhood Hits	9	Shared Neighborhood Hits	4
SwissProt Accessions	Q9JI19	Gene names	Fibp
Domain Architecture
Description	Acidic fibroblast growth factor intracellular-binding protein (aFGF intracellular-binding protein) (FGF-1 intracellular-binding protein).

SIL1_HUMAN
NC score	0.019907 (rank : 115)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	144	Target Neighborhood Hits	68	Shared Neighborhood Hits	12
SwissProt Accessions	Q9H173, Q8N2L3	Gene names	SIL1
Domain Architecture	No domain graphic available
Description	Nucleotide exchange factor SIL1 precursor (BiP-associated protein) (BAP).

LACTB_HUMAN
NC score	0.018182 (rank : 116)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	144	Target Neighborhood Hits	62	Shared Neighborhood Hits	9
SwissProt Accessions	P83111, P83096	Gene names	LACTB
Domain Architecture
Description	Serine beta-lactamase-like protein LACTB.

SPTB1_MOUSE
NC score	0.017945 (rank : 117)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	144	Target Neighborhood Hits	543	Shared Neighborhood Hits	42
SwissProt Accessions	P15508	Gene names	Sptb, Spnb-1, Spnb1, Sptb1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

VPS41_MOUSE
NC score	0.016923 (rank : 118)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	144	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q5KU39, Q3TPS1, Q80V99, Q8BKK6, Q8CG01, Q8CJC3	Gene names	Vps41
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 41 homolog (VAM2 homolog) (mVAM2).

VPS41_HUMAN
NC score	0.016617 (rank : 119)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	144	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	P49754, Q99851, Q99852	Gene names	VPS41
Domain Architecture
Description	Vacuolar protein sorting-associated protein 41 homolog (S53).

GRP78_HUMAN
NC score	0.016462 (rank : 120)	θ value	5.27518 (rank : 95)
Query Neighborhood Hits	144	Target Neighborhood Hits	218	Shared Neighborhood Hits	27
SwissProt Accessions	P11021, Q2EF78, Q9NPF1, Q9UK02	Gene names	HSPA5, GRP78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78).

GRP78_MOUSE
NC score	0.016397 (rank : 121)	θ value	5.27518 (rank : 96)
Query Neighborhood Hits	144	Target Neighborhood Hits	216	Shared Neighborhood Hits	26
SwissProt Accessions	P20029, O35642, Q3UFF2, Q61630	Gene names	Hspa5, Grp78
Domain Architecture
Description	78 kDa glucose-regulated protein precursor (GRP 78) (Heat shock 70 kDa protein 5) (Immunoglobulin heavy chain-binding protein) (BiP).

ROCK1_HUMAN
NC score	0.015961 (rank : 122)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	144	Target Neighborhood Hits	2000	Shared Neighborhood Hits	69
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

AT10A_HUMAN
NC score	0.014919 (rank : 123)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	144	Target Neighborhood Hits	98	Shared Neighborhood Hits	6
SwissProt Accessions	O60312, Q969I4	Gene names	ATP10A, ATP10C, ATPVC, KIAA0566
Domain Architecture	No domain graphic available
Description	Probable phospholipid-transporting ATPase VA (EC 3.6.3.1) (ATPVA) (Aminophospholipid translocase VA).

RPGR_HUMAN
NC score	0.014761 (rank : 124)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	144	Target Neighborhood Hits	279	Shared Neighborhood Hits	29
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

E2F6_MOUSE
NC score	0.014352 (rank : 125)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	144	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	O54917	Gene names	E2f6
Domain Architecture
Description	Transcription factor E2F6 (E2F-6) (E2F-binding site-modulating activity protein) (EMA).

TEX14_HUMAN
NC score	0.014045 (rank : 126)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	144	Target Neighborhood Hits	1103	Shared Neighborhood Hits	39
SwissProt Accessions	Q8IWB6, Q7RTP3, Q8ND97, Q9BXT9	Gene names	TEX14
Domain Architecture	No domain graphic available
Description	Testis-expressed protein 14 (Testis-expressed sequence 14).

MYRIP_HUMAN
NC score	0.013257 (rank : 127)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	144	Target Neighborhood Hits	269	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NFW9, Q8IUF5, Q9Y3V4	Gene names	MYRIP, SLAC2C
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

MRE11_HUMAN
NC score	0.012736 (rank : 128)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	144	Target Neighborhood Hits	95	Shared Neighborhood Hits	9
SwissProt Accessions	P49959, O43475	Gene names	MRE11A, HNGS1, MRE11
Domain Architecture
Description	Double-strand break repair protein MRE11A (MRE11 homolog 1) (MRE11 meiotic recombination 11 homolog A).

AXN2_MOUSE
NC score	0.011809 (rank : 129)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	144	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	O88566, Q9QXJ6	Gene names	Axin2
Domain Architecture
Description	Axin-2 (Axis inhibition protein 2) (Conductin) (Axin-like protein) (Axil).

CHD9_HUMAN
NC score	0.011701 (rank : 130)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	144	Target Neighborhood Hits	343	Shared Neighborhood Hits	24
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

OXSR1_MOUSE
NC score	0.011698 (rank : 131)	θ value	0.47712 (rank : 33)
Query Neighborhood Hits	144	Target Neighborhood Hits	865	Shared Neighborhood Hits	12
SwissProt Accessions	Q6P9R2, Q8BVZ9, Q8C0B9	Gene names	Oxsr1, Osr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

ANK2_HUMAN
NC score	0.011427 (rank : 132)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	144	Target Neighborhood Hits	1615	Shared Neighborhood Hits	54
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

PEG3_MOUSE
NC score	0.011017 (rank : 133)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	144	Target Neighborhood Hits	1101	Shared Neighborhood Hits	28
SwissProt Accessions	Q3URU2, O54978, Q3TQ69, Q5EBP7, Q61138, Q6GQS0, Q80U47, Q8R5N0, Q9QX53	Gene names	Peg3, Kiaa0287, Pw1
Domain Architecture	No domain graphic available
Description	Paternally expressed gene 3 protein (ASF-1).

PITX2_HUMAN
NC score	0.011002 (rank : 134)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	144	Target Neighborhood Hits	381	Shared Neighborhood Hits	7
SwissProt Accessions	Q99697, O60578, O60579, O60580, Q9BY17	Gene names	PITX2, ARP1, RGS, RIEG, RIEG1
Domain Architecture
Description	Pituitary homeobox 2 (RIEG bicoid-related homeobox transcription factor) (Solurshin) (ALL1-responsive protein ARP1).

CHD3_HUMAN
NC score	0.010885 (rank : 135)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	144	Target Neighborhood Hits	397	Shared Neighborhood Hits	26
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD6_HUMAN
NC score	0.010819 (rank : 136)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	144	Target Neighborhood Hits	342	Shared Neighborhood Hits	24
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

OXSR1_HUMAN
NC score	0.010467 (rank : 137)	θ value	0.62314 (rank : 38)
Query Neighborhood Hits	144	Target Neighborhood Hits	874	Shared Neighborhood Hits	11
SwissProt Accessions	O95747, Q3LR53, Q7Z501, Q9UPQ1	Gene names	OXSR1, KIAA1101, OSR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress- responsive 1 protein).

DIAP3_HUMAN
NC score	0.010172 (rank : 138)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	144	Target Neighborhood Hits	209	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

ACHA9_HUMAN
NC score	0.009582 (rank : 139)	θ value	1.38821 (rank : 52)
Query Neighborhood Hits	144	Target Neighborhood Hits	84	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGM1, Q4W5A2, Q9NYV2	Gene names	CHRNA9, NACHRA9
Domain Architecture
Description	Neuronal acetylcholine receptor protein subunit alpha-9 precursor (Nicotinic acetylcholine receptor subunit alpha 9) (NACHR alpha 9).

TAOK3_HUMAN
NC score	0.009292 (rank : 140)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	144	Target Neighborhood Hits	1494	Shared Neighborhood Hits	54
SwissProt Accessions	Q9H2K8, Q658N1, Q8IUM4, Q9HC79, Q9NZM9, Q9UHG7	Gene names	TAOK3, DPK, JIK, KDS, MAP3K18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO3 (EC 2.7.11.1) (Thousand and one amino acid protein 3) (Jun kinase-inhibitory kinase) (JNK/SAPK- inhibitory kinase) (Dendritic cell-derived protein kinase) (Cutaneous T-cell lymphoma tumor antigen HD-CL-09) (CTCL tumor antigen HD-CL-09) (Kinase from chicken homolog A) (hKFC-A).

OSBL8_HUMAN
NC score	0.009138 (rank : 141)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	144	Target Neighborhood Hits	289	Shared Neighborhood Hits	18
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

PDCL2_HUMAN
NC score	0.009110 (rank : 142)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	144	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N4E4	Gene names	PDCL2
Domain Architecture	No domain graphic available
Description	Phosducin-like protein 2.

CLGN_MOUSE
NC score	0.009016 (rank : 143)	θ value	6.88961 (rank : 106)
Query Neighborhood Hits	144	Target Neighborhood Hits	142	Shared Neighborhood Hits	12
SwissProt Accessions	P52194, Q9D2K5	Gene names	Clgn, Meg1
Domain Architecture
Description	Calmegin precursor (MEG 1 antigen) (Calnexin-T) (A2/6).

ARHG7_MOUSE
NC score	0.008390 (rank : 144)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	144	Target Neighborhood Hits	396	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ES28, O08757, Q9ES27	Gene names	Arhgef7, Pak3bp
Domain Architecture
Description	Rho guanine nucleotide exchange factor 7 (PAK-interacting exchange factor beta) (Beta-Pix) (p85SPR).

PITX2_MOUSE
NC score	0.007773 (rank : 145)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	144	Target Neighborhood Hits	383	Shared Neighborhood Hits	9
SwissProt Accessions	P97474, O08646, O70336, P97933, Q9JLA0, Q9QXB8, Q9R1V9, Q9Z141	Gene names	Pitx2, Arp1, Brx1, Otlx2, Ptx2, Rgs
Domain Architecture
Description	Pituitary homeobox 2 (Orthodenticle-like homeobox 2) (Solurshin) (ALL1-responsive protein ARP1) (BRX1 homeoprotein) (Paired-like homeodomain transcription factor Munc 30).

RAE1_MOUSE
NC score	0.007582 (rank : 146)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	144	Target Neighborhood Hits	32	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXG2, Q80UV8	Gene names	Chm, Rep1
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 1 (Rab escort protein 1) (REP-1) (Choroideraemia protein homolog).

STK39_MOUSE
NC score	0.006969 (rank : 147)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	144	Target Neighborhood Hits	915	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1W9, Q80W13	Gene names	Stk39, Spak
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39).

SHOX_HUMAN
NC score	0.006568 (rank : 148)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	144	Target Neighborhood Hits	363	Shared Neighborhood Hits	7
SwissProt Accessions	O15266, O00412, O00413, O15267	Gene names	SHOX, PHOG
Domain Architecture
Description	Short stature homeobox protein (Short stature homeobox-containing protein) (Pseudoautosomal homeobox-containing osteogenic protein).

STK39_HUMAN
NC score	0.006400 (rank : 149)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	144	Target Neighborhood Hits	882	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UEW8, O14774, Q9UER4	Gene names	STK39, SPAK
Domain Architecture
Description	STE20/SPS1-related proline-alanine-rich protein kinase (EC 2.7.11.1) (Ste-20-related kinase) (Serine/threonine-protein kinase 39) (DCHT).

ZA2G_MOUSE
NC score	0.006070 (rank : 150)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	144	Target Neighborhood Hits	174	Shared Neighborhood Hits	5
SwissProt Accessions	Q64726	Gene names	Azgp1
Domain Architecture
Description	Zinc-alpha-2-glycoprotein precursor (Zn-alpha-2-glycoprotein) (Zn- alpha-2-GP).

ZBT40_HUMAN
NC score	-0.000315 (rank : 151)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	144	Target Neighborhood Hits	949	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.