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Network neighborhood for query Sequence : SET_HUMAN

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SET_HUMAN
SwissProt Accessions	Q01105, Q15541, Q5VXV1	Gene names	SET
Domain Architecture
Description	Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template- activating factor I) (TAF-I) (HLA-DR-associated protein II) (PHAPII) (Inhibitor of granzyme A-activated DNase) (IGAAD).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SET_HUMAN
θ value	2.36115e-125 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	Q01105, Q15541, Q5VXV1	Gene names	SET
Domain Architecture
Description	Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template- activating factor I) (TAF-I) (HLA-DR-associated protein II) (PHAPII) (Inhibitor of granzyme A-activated DNase) (IGAAD).

SET_MOUSE
θ value	2.70151e-121 (rank : 2)	NC score	0.994480 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	61	Shared Neighborhood Hits	50
SwissProt Accessions	Q9EQU5, Q9CY82, Q9D0A9, Q9Z181	Gene names	Set
Domain Architecture
Description	Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template- activating factor I) (TAF-I).

TSYL1_HUMAN
θ value	8.89434e-40 (rank : 3)	NC score	0.907027 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H0U9, O75885	Gene names	TSPYL1, TSPYL
Domain Architecture
Description	Testis-specific Y-encoded-like protein 1 (TSPY-like 1).

TSYL1_MOUSE
θ value	1.16164e-39 (rank : 4)	NC score	0.893117 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	105	Shared Neighborhood Hits	17
SwissProt Accessions	O88852, Q3TKW0	Gene names	Tspyl1, Tspyl
Domain Architecture
Description	Testis-specific Y-encoded-like protein 1 (TSPY-like 1).

TSYL4_HUMAN
θ value	1.28434e-38 (rank : 5)	NC score	0.903677 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UJ04, O94828, Q96GW8	Gene names	TSPYL4, KIAA0721
Domain Architecture
Description	Testis-specific Y-encoded-like protein 4 (TSPY-like 4).

TSYL3_HUMAN
θ value	8.32485e-38 (rank : 6)	NC score	0.902713 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H489, Q3MJ63, Q3MJ65	Gene names	TSPYL3
Domain Architecture
Description	Testis-specific Y-encoded-like protein 3 (TSPY-like 3).

TSYL4_MOUSE
θ value	8.32485e-38 (rank : 7)	NC score	0.903643 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VD63	Gene names	Tspyl4, D10Bwg0791e
Domain Architecture
Description	Testis-specific Y-encoded-like protein 4 (TSPY-like 4).

TSPY1_HUMAN
θ value	3.86705e-35 (rank : 8)	NC score	0.908758 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q01534, O00216, P09002, Q9UNN7	Gene names	TSPY1, TSPY
Domain Architecture
Description	Testis-specific Y-encoded protein 1.

NP1L1_MOUSE
θ value	1.133e-10 (rank : 9)	NC score	0.572280 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	52	Shared Neighborhood Hits	19
SwissProt Accessions	P28656, Q3UL14	Gene names	Nap1l1, Nrp
Domain Architecture
Description	Nucleosome assembly protein 1-like 1 (NAP-1-related protein) (Brain protein DN38).

NP1L1_HUMAN
θ value	1.47974e-10 (rank : 10)	NC score	0.573550 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	54	Shared Neighborhood Hits	19
SwissProt Accessions	P55209	Gene names	NAP1L1, NRP
Domain Architecture
Description	Nucleosome assembly protein 1-like 1 (NAP-1-related protein) (hNRP).

NP1L4_HUMAN
θ value	1.63604e-09 (rank : 11)	NC score	0.548122 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	30	Shared Neighborhood Hits	19
SwissProt Accessions	Q99733	Gene names	NAP1L4, NAP2
Domain Architecture
Description	Nucleosome assembly protein 1-like 4 (Nucleosome assembly protein 2) (NAP2).

NP1L4_MOUSE
θ value	1.63604e-09 (rank : 12)	NC score	0.542983 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q78ZA7, O88701	Gene names	Nap1l4
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 4.

NP1L2_HUMAN
θ value	6.21693e-09 (rank : 13)	NC score	0.560805 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULW6, Q8TAN6	Gene names	NAP1L2, BPX
Domain Architecture
Description	Nucleosome assembly protein 1-like 2 (Brain-specific protein, X- linked).

NP1L3_HUMAN
θ value	8.11959e-09 (rank : 14)	NC score	0.568135 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	172	Shared Neighborhood Hits	26
SwissProt Accessions	Q99457, O60788	Gene names	NAP1L3, BNAP
Domain Architecture
Description	Nucleosome assembly protein 1-like 3.

NP1L2_MOUSE
θ value	2.61198e-07 (rank : 15)	NC score	0.545914 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	P51860	Gene names	Nap1l2, Bpx
Domain Architecture
Description	Nucleosome assembly protein 1-like 2 (Brain-specific protein, X- linked).

NP1L3_MOUSE
θ value	3.41135e-07 (rank : 16)	NC score	0.549228 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	233	Shared Neighborhood Hits	29
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

NSBP1_MOUSE
θ value	0.00102713 (rank : 17)	NC score	0.111260 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	681	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

LEO1_HUMAN
θ value	0.00298849 (rank : 18)	NC score	0.099999 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	958	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
θ value	0.00509761 (rank : 19)	NC score	0.093077 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	946	Shared Neighborhood Hits	35
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

TCAL5_HUMAN
θ value	0.00665767 (rank : 20)	NC score	0.080897 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	806	Shared Neighborhood Hits	27
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

CC47_MOUSE
θ value	0.0330416 (rank : 21)	NC score	0.100064 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	245	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

ERIC1_HUMAN
θ value	0.0431538 (rank : 22)	NC score	0.094514 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	364	Shared Neighborhood Hits	18
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

RBCC1_HUMAN
θ value	0.0961366 (rank : 23)	NC score	0.029992 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	1023	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

SYAC_MOUSE
θ value	0.0961366 (rank : 24)	NC score	0.042761 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGQ7, Q8BXR0	Gene names	Aars
Domain Architecture
Description	Alanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS).

BMS1_HUMAN
θ value	0.163984 (rank : 25)	NC score	0.102878 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

VPS72_HUMAN
θ value	0.47712 (rank : 26)	NC score	0.068068 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	274	Shared Neighborhood Hits	14
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

VPS72_MOUSE
θ value	0.47712 (rank : 27)	NC score	0.067332 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	286	Shared Neighborhood Hits	16
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

SEC63_HUMAN
θ value	0.62314 (rank : 28)	NC score	0.060294 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	586	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

TCAL3_HUMAN
θ value	0.62314 (rank : 29)	NC score	0.081478 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	274	Shared Neighborhood Hits	17
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

GOGB1_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.016303 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	2297	Shared Neighborhood Hits	25
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

PLCB1_MOUSE
θ value	0.813845 (rank : 31)	NC score	0.024207 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	531	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

DCDC2_MOUSE
θ value	1.38821 (rank : 32)	NC score	0.042065 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	247	Shared Neighborhood Hits	13
SwissProt Accessions	Q5DU00, Q5SZU0, Q80Y99	Gene names	Dcdc2, Kiaa1154
Domain Architecture	No domain graphic available
Description	Doublecortin domain-containing protein 2.

KIF2C_MOUSE
θ value	1.38821 (rank : 33)	NC score	0.011064 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q922S8	Gene names	Kif2c
Domain Architecture
Description	Kinesin-like protein KIF2C (Mitotic centromere-associated kinesin) (MCAK).

SMRC1_MOUSE
θ value	1.38821 (rank : 34)	NC score	0.039548 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	459	Shared Neighborhood Hits	20
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

RP1L1_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.053138 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	1072	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SEC63_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.056738 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	601	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

TF3C4_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.022443 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKN8	Gene names	GTF3C4
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (Transcription factor IIIC subunit delta) (TF3C-delta) (TFIIIC 90 kDa subunit) (TFIIIC 90).

BRD8_MOUSE
θ value	3.0926 (rank : 38)	NC score	0.038401 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	422	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

CS007_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.026214 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	401	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

KS6B1_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.001725 (rank : 76)
Query Neighborhood Hits	71	Target Neighborhood Hits	850	Shared Neighborhood Hits	5
SwissProt Accessions	P23443	Gene names	RPS6KB1
Domain Architecture
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K) (p70-alpha).

KS6B1_MOUSE
θ value	3.0926 (rank : 41)	NC score	0.001725 (rank : 75)
Query Neighborhood Hits	71	Target Neighborhood Hits	849	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BSK8, Q8CHX0	Gene names	Rps6kb1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K).

STK4_HUMAN
θ value	3.0926 (rank : 42)	NC score	-0.000447 (rank : 77)
Query Neighborhood Hits	71	Target Neighborhood Hits	870	Shared Neighborhood Hits	5
SwissProt Accessions	Q13043, Q15802, Q4G156, Q5H982, Q6PD60, Q9BR32, Q9NTZ4	Gene names	STK4, MST1
Domain Architecture
Description	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2).

SV2C_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.021514 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	124	Shared Neighborhood Hits	10
SwissProt Accessions	Q496J9, Q496K1, Q9UPU8	Gene names	SV2C, KIAA1054
Domain Architecture	No domain graphic available
Description	Synaptic vesicle glycoprotein 2C.

AKA12_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.042622 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	825	Shared Neighborhood Hits	26
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

CF141_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.029475 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SZD1, Q8N400, Q96NQ1	Gene names	C6orf141
Domain Architecture	No domain graphic available
Description	Protein C6orf141.

DDX46_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.013032 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	358	Shared Neighborhood Hits	15
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

IF2B_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.022575 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	P20042, Q9BVU0, Q9UJE4	Gene names	EIF2S2, EIF2B
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta).

LRC45_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.010029 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	933	Shared Neighborhood Hits	11
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

RAI14_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.004550 (rank : 73)
Query Neighborhood Hits	71	Target Neighborhood Hits	1367	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

TBA1_HUMAN
θ value	4.03905 (rank : 50)	NC score	0.008378 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	P68366, P05215	Gene names	TUBA1
Domain Architecture	No domain graphic available
Description	Tubulin alpha-1 chain (Alpha-tubulin 1) (Testis-specific alpha- tubulin) (Tubulin H2-alpha).

TBA4_MOUSE
θ value	4.03905 (rank : 51)	NC score	0.008378 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	P68368, P05215	Gene names	Tuba4
Domain Architecture	No domain graphic available
Description	Tubulin alpha-4 chain (Alpha-tubulin 4) (Alpha-tubulin isotype M- alpha-4).

VAV_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.007816 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	452	Shared Neighborhood Hits	4
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

ARRS_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.009517 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	P20443, Q91W62	Gene names	Sag
Domain Architecture
Description	S-arrestin (Retinal S-antigen) (48 kDa protein) (S-AG) (Rod photoreceptor arrestin).

CCD47_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.072246 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	119	Shared Neighborhood Hits	8
SwissProt Accessions	Q96A33, Q96D00, Q96JZ7, Q9H3E4, Q9NRG3	Gene names	CCDC47
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor.

CENPC_MOUSE
θ value	5.27518 (rank : 55)	NC score	0.026496 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	154	Shared Neighborhood Hits	7
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

EEA1_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.007471 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	1796	Shared Neighborhood Hits	16
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

IRX2_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.010536 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	358	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BZI1, Q7Z2I7	Gene names	IRX2, IRXA2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

BRD8_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.022752 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	292	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

CCD46_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.015987 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	1430	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CIC_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.008505 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	992	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
θ value	6.88961 (rank : 61)	NC score	0.009812 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	742	Shared Neighborhood Hits	6
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

DCDC2_HUMAN
θ value	6.88961 (rank : 62)	NC score	0.030836 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	127	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHG0, Q5VTR8, Q5VTR9, Q86W35, Q9UFD1, Q9ULR6	Gene names	DCDC2, KIAA1154
Domain Architecture
Description	Doublecortin domain-containing protein 2 (RU2S protein).

OSBL8_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.022283 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	289	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

RASF5_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.014169 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q5EBH1, O70407, Q6KAR0, Q8C2E8	Gene names	Rassf5, Nore1, Rapl
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

TCF8_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.004262 (rank : 74)
Query Neighborhood Hits	71	Target Neighborhood Hits	1057	Shared Neighborhood Hits	21
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

TRPM3_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.010884 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	121	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

VAV_MOUSE
θ value	6.88961 (rank : 67)	NC score	0.006952 (rank : 72)
Query Neighborhood Hits	71	Target Neighborhood Hits	430	Shared Neighborhood Hits	3
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

PCLO_MOUSE
θ value	8.99809 (rank : 68)	NC score	0.010373 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	2275	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RASF5_HUMAN
θ value	8.99809 (rank : 69)	NC score	0.013370 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWW0, Q5SY32, Q8WWV9, Q8WXF4, Q9BT99	Gene names	RASSF5, NORE1, RAPL
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

RASF6_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.010736 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZTQ3, Q68DT2, Q6PDA6, Q86WG9, Q86WH0	Gene names	RASSF6
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 6.

SMRC2_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.031125 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	499	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

NSBP1_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.064210 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	251	Shared Neighborhood Hits	19
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

PTMA_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.086229 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

PTMA_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.081258 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

PTMS_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.063986 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	111	Shared Neighborhood Hits	14
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

PTMS_MOUSE
θ value	θ > 10 (rank : 76)	NC score	0.073640 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	68	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

TCAL6_HUMAN
θ value	θ > 10 (rank : 77)	NC score	0.053041 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	122	Shared Neighborhood Hits	9
SwissProt Accessions	Q6IPX3, Q5H9J8	Gene names	TCEAL6
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 6 (TCEA-like protein 6) (Transcription elongation factor S-II protein-like 6).

Hits sorted by NC score

SET_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.36115e-125 (rank : 1)
Query Neighborhood Hits	71	Target Neighborhood Hits	71	Shared Neighborhood Hits	71
SwissProt Accessions	Q01105, Q15541, Q5VXV1	Gene names	SET
Domain Architecture
Description	Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template- activating factor I) (TAF-I) (HLA-DR-associated protein II) (PHAPII) (Inhibitor of granzyme A-activated DNase) (IGAAD).

SET_MOUSE
NC score	0.994480 (rank : 2)	θ value	2.70151e-121 (rank : 2)
Query Neighborhood Hits	71	Target Neighborhood Hits	61	Shared Neighborhood Hits	50
SwissProt Accessions	Q9EQU5, Q9CY82, Q9D0A9, Q9Z181	Gene names	Set
Domain Architecture
Description	Protein SET (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template- activating factor I) (TAF-I).

TSPY1_HUMAN
NC score	0.908758 (rank : 3)	θ value	3.86705e-35 (rank : 8)
Query Neighborhood Hits	71	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q01534, O00216, P09002, Q9UNN7	Gene names	TSPY1, TSPY
Domain Architecture
Description	Testis-specific Y-encoded protein 1.

TSYL1_HUMAN
NC score	0.907027 (rank : 4)	θ value	8.89434e-40 (rank : 3)
Query Neighborhood Hits	71	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H0U9, O75885	Gene names	TSPYL1, TSPYL
Domain Architecture
Description	Testis-specific Y-encoded-like protein 1 (TSPY-like 1).

TSYL4_HUMAN
NC score	0.903677 (rank : 5)	θ value	1.28434e-38 (rank : 5)
Query Neighborhood Hits	71	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UJ04, O94828, Q96GW8	Gene names	TSPYL4, KIAA0721
Domain Architecture
Description	Testis-specific Y-encoded-like protein 4 (TSPY-like 4).

TSYL4_MOUSE
NC score	0.903643 (rank : 6)	θ value	8.32485e-38 (rank : 7)
Query Neighborhood Hits	71	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	Q8VD63	Gene names	Tspyl4, D10Bwg0791e
Domain Architecture
Description	Testis-specific Y-encoded-like protein 4 (TSPY-like 4).

TSYL3_HUMAN
NC score	0.902713 (rank : 7)	θ value	8.32485e-38 (rank : 6)
Query Neighborhood Hits	71	Target Neighborhood Hits	36	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H489, Q3MJ63, Q3MJ65	Gene names	TSPYL3
Domain Architecture
Description	Testis-specific Y-encoded-like protein 3 (TSPY-like 3).

TSYL1_MOUSE
NC score	0.893117 (rank : 8)	θ value	1.16164e-39 (rank : 4)
Query Neighborhood Hits	71	Target Neighborhood Hits	105	Shared Neighborhood Hits	17
SwissProt Accessions	O88852, Q3TKW0	Gene names	Tspyl1, Tspyl
Domain Architecture
Description	Testis-specific Y-encoded-like protein 1 (TSPY-like 1).

NP1L1_HUMAN
NC score	0.573550 (rank : 9)	θ value	1.47974e-10 (rank : 10)
Query Neighborhood Hits	71	Target Neighborhood Hits	54	Shared Neighborhood Hits	19
SwissProt Accessions	P55209	Gene names	NAP1L1, NRP
Domain Architecture
Description	Nucleosome assembly protein 1-like 1 (NAP-1-related protein) (hNRP).

NP1L1_MOUSE
NC score	0.572280 (rank : 10)	θ value	1.133e-10 (rank : 9)
Query Neighborhood Hits	71	Target Neighborhood Hits	52	Shared Neighborhood Hits	19
SwissProt Accessions	P28656, Q3UL14	Gene names	Nap1l1, Nrp
Domain Architecture
Description	Nucleosome assembly protein 1-like 1 (NAP-1-related protein) (Brain protein DN38).

NP1L3_HUMAN
NC score	0.568135 (rank : 11)	θ value	8.11959e-09 (rank : 14)
Query Neighborhood Hits	71	Target Neighborhood Hits	172	Shared Neighborhood Hits	26
SwissProt Accessions	Q99457, O60788	Gene names	NAP1L3, BNAP
Domain Architecture
Description	Nucleosome assembly protein 1-like 3.

NP1L2_HUMAN
NC score	0.560805 (rank : 12)	θ value	6.21693e-09 (rank : 13)
Query Neighborhood Hits	71	Target Neighborhood Hits	34	Shared Neighborhood Hits	22
SwissProt Accessions	Q9ULW6, Q8TAN6	Gene names	NAP1L2, BPX
Domain Architecture
Description	Nucleosome assembly protein 1-like 2 (Brain-specific protein, X- linked).

NP1L3_MOUSE
NC score	0.549228 (rank : 13)	θ value	3.41135e-07 (rank : 16)
Query Neighborhood Hits	71	Target Neighborhood Hits	233	Shared Neighborhood Hits	29
SwissProt Accessions	Q794H2, O54802	Gene names	Nap1l3, Mb20
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 3 (Brain-specific protein MB20).

NP1L4_HUMAN
NC score	0.548122 (rank : 14)	θ value	1.63604e-09 (rank : 11)
Query Neighborhood Hits	71	Target Neighborhood Hits	30	Shared Neighborhood Hits	19
SwissProt Accessions	Q99733	Gene names	NAP1L4, NAP2
Domain Architecture
Description	Nucleosome assembly protein 1-like 4 (Nucleosome assembly protein 2) (NAP2).

NP1L2_MOUSE
NC score	0.545914 (rank : 15)	θ value	2.61198e-07 (rank : 15)
Query Neighborhood Hits	71	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	P51860	Gene names	Nap1l2, Bpx
Domain Architecture
Description	Nucleosome assembly protein 1-like 2 (Brain-specific protein, X- linked).

NP1L4_MOUSE
NC score	0.542983 (rank : 16)	θ value	1.63604e-09 (rank : 12)
Query Neighborhood Hits	71	Target Neighborhood Hits	41	Shared Neighborhood Hits	18
SwissProt Accessions	Q78ZA7, O88701	Gene names	Nap1l4
Domain Architecture	No domain graphic available
Description	Nucleosome assembly protein 1-like 4.

NSBP1_MOUSE
NC score	0.111260 (rank : 17)	θ value	0.00102713 (rank : 17)
Query Neighborhood Hits	71	Target Neighborhood Hits	681	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

BMS1_HUMAN
NC score	0.102878 (rank : 18)	θ value	0.163984 (rank : 25)
Query Neighborhood Hits	71	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

CC47_MOUSE
NC score	0.100064 (rank : 19)	θ value	0.0330416 (rank : 21)
Query Neighborhood Hits	71	Target Neighborhood Hits	245	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

LEO1_HUMAN
NC score	0.099999 (rank : 20)	θ value	0.00298849 (rank : 18)
Query Neighborhood Hits	71	Target Neighborhood Hits	958	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

ERIC1_HUMAN
NC score	0.094514 (rank : 21)	θ value	0.0431538 (rank : 22)
Query Neighborhood Hits	71	Target Neighborhood Hits	364	Shared Neighborhood Hits	18
SwissProt Accessions	Q86X53, Q9P063	Gene names	ERICH1
Domain Architecture	No domain graphic available
Description	Glutamate-rich protein 1.

LEO1_MOUSE
NC score	0.093077 (rank : 22)	θ value	0.00509761 (rank : 19)
Query Neighborhood Hits	71	Target Neighborhood Hits	946	Shared Neighborhood Hits	35
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

PTMA_HUMAN
NC score	0.086229 (rank : 23)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	71	Target Neighborhood Hits	88	Shared Neighborhood Hits	15
SwissProt Accessions	P06454, Q15249, Q15592	Gene names	PTMA, TMSA
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha-1].

TCAL3_HUMAN
NC score	0.081478 (rank : 24)	θ value	0.62314 (rank : 29)
Query Neighborhood Hits	71	Target Neighborhood Hits	274	Shared Neighborhood Hits	17
SwissProt Accessions	Q969E4	Gene names	TCEAL3
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 3 (TCEA-like protein 3) (Transcription elongation factor S-II protein-like 3).

PTMA_MOUSE
NC score	0.081258 (rank : 25)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	71	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	P26350, Q3UQV6	Gene names	Ptma
Domain Architecture	No domain graphic available
Description	Prothymosin alpha [Contains: Thymosin alpha].

TCAL5_HUMAN
NC score	0.080897 (rank : 26)	θ value	0.00665767 (rank : 20)
Query Neighborhood Hits	71	Target Neighborhood Hits	806	Shared Neighborhood Hits	27
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

PTMS_MOUSE
NC score	0.073640 (rank : 27)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	71	Target Neighborhood Hits	68	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D0J8	Gene names	Ptms
Domain Architecture	No domain graphic available
Description	Parathymosin.

CCD47_HUMAN
NC score	0.072246 (rank : 28)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	71	Target Neighborhood Hits	119	Shared Neighborhood Hits	8
SwissProt Accessions	Q96A33, Q96D00, Q96JZ7, Q9H3E4, Q9NRG3	Gene names	CCDC47
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor.

VPS72_HUMAN
NC score	0.068068 (rank : 29)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	71	Target Neighborhood Hits	274	Shared Neighborhood Hits	14
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

VPS72_MOUSE
NC score	0.067332 (rank : 30)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	71	Target Neighborhood Hits	286	Shared Neighborhood Hits	16
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

NSBP1_HUMAN
NC score	0.064210 (rank : 31)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	71	Target Neighborhood Hits	251	Shared Neighborhood Hits	19
SwissProt Accessions	P82970	Gene names	NSBP1
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1.

PTMS_HUMAN
NC score	0.063986 (rank : 32)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	71	Target Neighborhood Hits	111	Shared Neighborhood Hits	14
SwissProt Accessions	P20962	Gene names	PTMS
Domain Architecture	No domain graphic available
Description	Parathymosin.

SEC63_HUMAN
NC score	0.060294 (rank : 33)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	71	Target Neighborhood Hits	586	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UGP8, O95380, Q86VS9, Q8IWL0, Q9NTE0	Gene names	SEC63, SEC63L
Domain Architecture
Description	Translocation protein SEC63 homolog.

SEC63_MOUSE
NC score	0.056738 (rank : 34)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	71	Target Neighborhood Hits	601	Shared Neighborhood Hits	24
SwissProt Accessions	Q8VHE0, Q8VEB9	Gene names	Sec63, Sec63l
Domain Architecture
Description	Translocation protein SEC63 homolog.

RP1L1_HUMAN
NC score	0.053138 (rank : 35)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	71	Target Neighborhood Hits	1072	Shared Neighborhood Hits	27
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

TCAL6_HUMAN
NC score	0.053041 (rank : 36)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	71	Target Neighborhood Hits	122	Shared Neighborhood Hits	9
SwissProt Accessions	Q6IPX3, Q5H9J8	Gene names	TCEAL6
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 6 (TCEA-like protein 6) (Transcription elongation factor S-II protein-like 6).

SYAC_MOUSE
NC score	0.042761 (rank : 37)	θ value	0.0961366 (rank : 24)
Query Neighborhood Hits	71	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGQ7, Q8BXR0	Gene names	Aars
Domain Architecture
Description	Alanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.7) (Alanine--tRNA ligase) (AlaRS).

AKA12_HUMAN
NC score	0.042622 (rank : 38)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	71	Target Neighborhood Hits	825	Shared Neighborhood Hits	26
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

DCDC2_MOUSE
NC score	0.042065 (rank : 39)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	71	Target Neighborhood Hits	247	Shared Neighborhood Hits	13
SwissProt Accessions	Q5DU00, Q5SZU0, Q80Y99	Gene names	Dcdc2, Kiaa1154
Domain Architecture	No domain graphic available
Description	Doublecortin domain-containing protein 2.

SMRC1_MOUSE
NC score	0.039548 (rank : 40)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	71	Target Neighborhood Hits	459	Shared Neighborhood Hits	20
SwissProt Accessions	P97496, Q7TS80, Q7TT29	Gene names	Smarcc1, Baf155, Srg3
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 (SWI/SNF complex 155 kDa subunit) (BRG1-associated factor 155) (SWI3-related protein).

BRD8_MOUSE
NC score	0.038401 (rank : 41)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	71	Target Neighborhood Hits	422	Shared Neighborhood Hits	17
SwissProt Accessions	Q8R3B7, Q8C049, Q8R583, Q8VDP0	Gene names	Brd8
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8.

SMRC2_HUMAN
NC score	0.031125 (rank : 42)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	71	Target Neighborhood Hits	499	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

DCDC2_HUMAN
NC score	0.030836 (rank : 43)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	71	Target Neighborhood Hits	127	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHG0, Q5VTR8, Q5VTR9, Q86W35, Q9UFD1, Q9ULR6	Gene names	DCDC2, KIAA1154
Domain Architecture
Description	Doublecortin domain-containing protein 2 (RU2S protein).

RBCC1_HUMAN
NC score	0.029992 (rank : 44)	θ value	0.0961366 (rank : 23)
Query Neighborhood Hits	71	Target Neighborhood Hits	1023	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

CF141_HUMAN
NC score	0.029475 (rank : 45)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	71	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SZD1, Q8N400, Q96NQ1	Gene names	C6orf141
Domain Architecture	No domain graphic available
Description	Protein C6orf141.

CENPC_MOUSE
NC score	0.026496 (rank : 46)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	71	Target Neighborhood Hits	154	Shared Neighborhood Hits	7
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

CS007_HUMAN
NC score	0.026214 (rank : 47)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	71	Target Neighborhood Hits	401	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UPT8, Q9Y420	Gene names	C19orf7, KIAA1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7.

PLCB1_MOUSE
NC score	0.024207 (rank : 48)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	71	Target Neighborhood Hits	531	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1B3, Q62075, Q8K5A5, Q8K5A6, Q9Z0E5, Q9Z2T5	Gene names	Plcb1, Plcb
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (Phospholipase C- beta-1) (PLC-beta-1) (PLC-I) (PLC-154).

BRD8_HUMAN
NC score	0.022752 (rank : 49)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	71	Target Neighborhood Hits	292	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H0E9, O43178, Q15355, Q59GN0, Q969M9	Gene names	BRD8, SMAP
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 8 (p120) (Skeletal muscle abundant protein) (Thyroid hormone receptor coactivating protein 120kDa) (TrCP120).

IF2B_HUMAN
NC score	0.022575 (rank : 50)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	71	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	P20042, Q9BVU0, Q9UJE4	Gene names	EIF2S2, EIF2B
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta).

TF3C4_HUMAN
NC score	0.022443 (rank : 51)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	71	Target Neighborhood Hits	25	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UKN8	Gene names	GTF3C4
Domain Architecture	No domain graphic available
Description	General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (Transcription factor IIIC subunit delta) (TF3C-delta) (TFIIIC 90 kDa subunit) (TFIIIC 90).

OSBL8_HUMAN
NC score	0.022283 (rank : 52)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	71	Target Neighborhood Hits	289	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BZF1, Q8WXP8, Q9P277	Gene names	OSBPL8, KIAA1451, ORP8, OSBP10
Domain Architecture
Description	Oxysterol-binding protein-related protein 8 (OSBP-related protein 8) (ORP-8).

SV2C_HUMAN
NC score	0.021514 (rank : 53)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	71	Target Neighborhood Hits	124	Shared Neighborhood Hits	10
SwissProt Accessions	Q496J9, Q496K1, Q9UPU8	Gene names	SV2C, KIAA1054
Domain Architecture	No domain graphic available
Description	Synaptic vesicle glycoprotein 2C.

GOGB1_HUMAN
NC score	0.016303 (rank : 54)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	71	Target Neighborhood Hits	2297	Shared Neighborhood Hits	25
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CCD46_HUMAN
NC score	0.015987 (rank : 55)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	71	Target Neighborhood Hits	1430	Shared Neighborhood Hits	19
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

RASF5_MOUSE
NC score	0.014169 (rank : 56)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	71	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	Q5EBH1, O70407, Q6KAR0, Q8C2E8	Gene names	Rassf5, Nore1, Rapl
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

RASF5_HUMAN
NC score	0.013370 (rank : 57)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	71	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWW0, Q5SY32, Q8WWV9, Q8WXF4, Q9BT99	Gene names	RASSF5, NORE1, RAPL
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

DDX46_MOUSE
NC score	0.013032 (rank : 58)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	71	Target Neighborhood Hits	358	Shared Neighborhood Hits	15
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

KIF2C_MOUSE
NC score	0.011064 (rank : 59)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	71	Target Neighborhood Hits	96	Shared Neighborhood Hits	3
SwissProt Accessions	Q922S8	Gene names	Kif2c
Domain Architecture
Description	Kinesin-like protein KIF2C (Mitotic centromere-associated kinesin) (MCAK).

TRPM3_HUMAN
NC score	0.010884 (rank : 60)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	71	Target Neighborhood Hits	121	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

RASF6_HUMAN
NC score	0.010736 (rank : 61)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	71	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q6ZTQ3, Q68DT2, Q6PDA6, Q86WG9, Q86WH0	Gene names	RASSF6
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 6.

IRX2_HUMAN
NC score	0.010536 (rank : 62)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	71	Target Neighborhood Hits	358	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BZI1, Q7Z2I7	Gene names	IRX2, IRXA2
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-2 (Iroquois homeobox protein 2) (Homeodomain protein IRXA2).

PCLO_MOUSE
NC score	0.010373 (rank : 63)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	71	Target Neighborhood Hits	2275	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

LRC45_HUMAN
NC score	0.010029 (rank : 64)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	71	Target Neighborhood Hits	933	Shared Neighborhood Hits	11
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

CIC_MOUSE
NC score	0.009812 (rank : 65)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	71	Target Neighborhood Hits	742	Shared Neighborhood Hits	6
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

ARRS_MOUSE
NC score	0.009517 (rank : 66)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	71	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	P20443, Q91W62	Gene names	Sag
Domain Architecture
Description	S-arrestin (Retinal S-antigen) (48 kDa protein) (S-AG) (Rod photoreceptor arrestin).

CIC_HUMAN
NC score	0.008505 (rank : 67)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	71	Target Neighborhood Hits	992	Shared Neighborhood Hits	8
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

TBA1_HUMAN
NC score	0.008378 (rank : 68)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	71	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	P68366, P05215	Gene names	TUBA1
Domain Architecture	No domain graphic available
Description	Tubulin alpha-1 chain (Alpha-tubulin 1) (Testis-specific alpha- tubulin) (Tubulin H2-alpha).

TBA4_MOUSE
NC score	0.008378 (rank : 69)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	71	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	P68368, P05215	Gene names	Tuba4
Domain Architecture	No domain graphic available
Description	Tubulin alpha-4 chain (Alpha-tubulin 4) (Alpha-tubulin isotype M- alpha-4).

VAV_HUMAN
NC score	0.007816 (rank : 70)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	71	Target Neighborhood Hits	452	Shared Neighborhood Hits	4
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

EEA1_HUMAN
NC score	0.007471 (rank : 71)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	71	Target Neighborhood Hits	1796	Shared Neighborhood Hits	16
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

VAV_MOUSE
NC score	0.006952 (rank : 72)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	71	Target Neighborhood Hits	430	Shared Neighborhood Hits	3
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

RAI14_HUMAN
NC score	0.004550 (rank : 73)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	71	Target Neighborhood Hits	1367	Shared Neighborhood Hits	11
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

TCF8_HUMAN
NC score	0.004262 (rank : 74)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	71	Target Neighborhood Hits	1057	Shared Neighborhood Hits	21
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

KS6B1_MOUSE
NC score	0.001725 (rank : 75)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	71	Target Neighborhood Hits	849	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BSK8, Q8CHX0	Gene names	Rps6kb1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K).

KS6B1_HUMAN
NC score	0.001725 (rank : 76)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	71	Target Neighborhood Hits	850	Shared Neighborhood Hits	5
SwissProt Accessions	P23443	Gene names	RPS6KB1
Domain Architecture
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K) (p70-alpha).

STK4_HUMAN
NC score	-0.000447 (rank : 77)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	71	Target Neighborhood Hits	870	Shared Neighborhood Hits	5
SwissProt Accessions	Q13043, Q15802, Q4G156, Q5H982, Q6PD60, Q9BR32, Q9NTZ4	Gene names	STK4, MST1
Domain Architecture
Description	Serine/threonine-protein kinase 4 (EC 2.7.11.1) (STE20-like kinase MST1) (MST-1) (Mammalian STE20-like protein kinase 1) (Serine/threonine-protein kinase Krs-2).