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Network neighborhood for query Sequence : PDIA3_HUMAN

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PDIA3_HUMAN
SwissProt Accessions	P30101, Q13453, Q14255, Q8IYF8, Q9UMU7	Gene names	PDIA3, ERP60, GRP58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57) (58 kDa glucose-regulated protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PDIA3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	57	Target Neighborhood Hits	57	Shared Neighborhood Hits	57
SwissProt Accessions	P30101, Q13453, Q14255, Q8IYF8, Q9UMU7	Gene names	PDIA3, ERP60, GRP58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57) (58 kDa glucose-regulated protein).

PDIA3_MOUSE
θ value	0 (rank : 2)	NC score	0.998436 (rank : 2)
Query Neighborhood Hits	57	Target Neighborhood Hits	58	Shared Neighborhood Hits	52
SwissProt Accessions	P27773	Gene names	Pdia3, Erp, Erp60, Grp58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57).

PDIA4_HUMAN
θ value	5.67233e-95 (rank : 3)	NC score	0.952521 (rank : 4)
Query Neighborhood Hits	57	Target Neighborhood Hits	60	Shared Neighborhood Hits	45
SwissProt Accessions	P13667	Gene names	PDIA4, ERP70, ERP72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

PDIA4_MOUSE
θ value	6.27148e-94 (rank : 4)	NC score	0.953166 (rank : 3)
Query Neighborhood Hits	57	Target Neighborhood Hits	57	Shared Neighborhood Hits	45
SwissProt Accessions	P08003, P15841	Gene names	Pdia4, Cai, Erp72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

PDIA1_MOUSE
θ value	1.11475e-66 (rank : 5)	NC score	0.931841 (rank : 6)
Query Neighborhood Hits	57	Target Neighborhood Hits	50	Shared Neighborhood Hits	44
SwissProt Accessions	P09103	Gene names	P4hb, Pdia1
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55) (Erp59).

PDIA1_HUMAN
θ value	1.2325e-65 (rank : 6)	NC score	0.935492 (rank : 5)
Query Neighborhood Hits	57	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	P07237, P30037, P32079, Q15205, Q6LDE5	Gene names	P4HB, PDI, PDIA1, PO4DB
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55).

PDIA2_HUMAN
θ value	2.66562e-52 (rank : 7)	NC score	0.927182 (rank : 7)
Query Neighborhood Hits	57	Target Neighborhood Hits	49	Shared Neighborhood Hits	41
SwissProt Accessions	Q13087, Q96KJ6, Q9BW95	Gene names	PDIA2, PDIP
Domain Architecture
Description	Protein disulfide-isomerase A2 precursor (EC 5.3.4.1) (PDIp).

PDIA6_MOUSE
θ value	8.08199e-25 (rank : 8)	NC score	0.825619 (rank : 9)
Query Neighborhood Hits	57	Target Neighborhood Hits	47	Shared Neighborhood Hits	44
SwissProt Accessions	Q922R8, Q8BK54	Gene names	Pdia6, Txndc7
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 7).

PDIA6_HUMAN
θ value	5.23862e-24 (rank : 9)	NC score	0.827577 (rank : 8)
Query Neighborhood Hits	57	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	Q15084, Q99778	Gene names	PDIA6, TXNDC7
Domain Architecture
Description	Protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7).

TXND5_MOUSE
θ value	5.79196e-23 (rank : 10)	NC score	0.820265 (rank : 10)
Query Neighborhood Hits	57	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	Q91W90, Q8R1I6	Gene names	Txndc5, Tlp46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46) (Plasma cell- specific thioredoxin-related protein) (PC-TRP).

TXND5_HUMAN
θ value	1.86321e-21 (rank : 11)	NC score	0.816032 (rank : 11)
Query Neighborhood Hits	57	Target Neighborhood Hits	54	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NBS9, Q8ND33, Q8TCT2, Q9BVH9	Gene names	TXNDC5, TLP46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46).

TXD10_MOUSE
θ value	1.47631e-18 (rank : 12)	NC score	0.760742 (rank : 12)
Query Neighborhood Hits	57	Target Neighborhood Hits	48	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BXZ1, Q3US84, Q6PGA1, Q6ZPH5, Q8BZB8	Gene names	Txndc10, Kiaa1830
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase TXNDC10 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 10).

TXD10_HUMAN
θ value	2.5182e-18 (rank : 13)	NC score	0.757717 (rank : 13)
Query Neighborhood Hits	57	Target Neighborhood Hits	47	Shared Neighborhood Hits	41
SwissProt Accessions	Q96JJ7, Q8N5J0, Q9NWJ9	Gene names	TXNDC10, KIAA1830, TMX3
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase TXNDC10 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 10) (Thioredoxin-related transmembrane protein 3).

TXND4_MOUSE
θ value	1.80466e-16 (rank : 14)	NC score	0.727193 (rank : 17)
Query Neighborhood Hits	57	Target Neighborhood Hits	44	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D1Q6, Q3TVI1, Q6A045	Gene names	Txndc4, Erp44, Kiaa0573
Domain Architecture
Description	Thioredoxin domain-containing protein 4 precursor (Endoplasmic reticulum resident protein ERp44).

TXND4_HUMAN
θ value	5.25075e-16 (rank : 15)	NC score	0.731577 (rank : 16)
Query Neighborhood Hits	57	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BS26, O60319, Q5VWZ7, Q6UW14, Q8WX67	Gene names	TXNDC4, ERP44, KIAA0573
Domain Architecture
Description	Thioredoxin domain-containing protein 4 precursor (Endoplasmic reticulum resident protein ERp44).

PDIA5_MOUSE
θ value	3.76295e-14 (rank : 16)	NC score	0.745988 (rank : 14)
Query Neighborhood Hits	57	Target Neighborhood Hits	46	Shared Neighborhood Hits	43
SwissProt Accessions	Q921X9	Gene names	Pdia5, Pdir
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

PDIA5_HUMAN
θ value	1.42992e-13 (rank : 17)	NC score	0.744954 (rank : 15)
Query Neighborhood Hits	57	Target Neighborhood Hits	42	Shared Neighborhood Hits	40
SwissProt Accessions	Q14554	Gene names	PDIA5, PDIR
Domain Architecture
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

TXD11_HUMAN
θ value	3.29651e-10 (rank : 18)	NC score	0.385160 (rank : 30)
Query Neighborhood Hits	57	Target Neighborhood Hits	402	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PKC3, O95887, Q6PJA6, Q8N2Q4, Q96K45, Q96K53	Gene names	TXNDC11, EFP1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1).

QSCN6_MOUSE
θ value	4.30538e-10 (rank : 19)	NC score	0.512544 (rank : 24)
Query Neighborhood Hits	57	Target Neighborhood Hits	62	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BND5, Q3TDY9, Q3TE19, Q3TR29, Q3UEL4, Q8K041, Q9DBL6	Gene names	Qscn6, Sox
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (Skin sulfhydryl oxidase) (mSOx).

TXND1_HUMAN
θ value	7.34386e-10 (rank : 20)	NC score	0.622282 (rank : 20)
Query Neighborhood Hits	57	Target Neighborhood Hits	38	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H3N1, Q8N487, Q8NBN5, Q9Y4T6	Gene names	TXNDC1, TMX, TXNDC
Domain Architecture
Description	Thioredoxin domain-containing protein 1 precursor (Transmembrane Trx- related protein) (Thioredoxin-related transmembrane protein).

TXND1_MOUSE
θ value	2.13673e-09 (rank : 21)	NC score	0.605522 (rank : 21)
Query Neighborhood Hits	57	Target Neighborhood Hits	36	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VBT0, Q3UCI8, Q9CSD5	Gene names	Txndc1, Txndc
Domain Architecture
Description	Thioredoxin domain-containing protein 1 precursor.

TXD11_MOUSE
θ value	3.64472e-09 (rank : 22)	NC score	0.417199 (rank : 29)
Query Neighborhood Hits	57	Target Neighborhood Hits	81	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K2W3, Q8BMR8, Q8VCK9	Gene names	Txndc11
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11.

QSCN6_HUMAN
θ value	4.76016e-09 (rank : 23)	NC score	0.492470 (rank : 25)
Query Neighborhood Hits	57	Target Neighborhood Hits	98	Shared Neighborhood Hits	32
SwissProt Accessions	O00391, Q59G29, Q5T2X0, Q8TDL6, Q8WVP4	Gene names	QSCN6, QSOX1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (hQSOX).

THIOM_HUMAN
θ value	4.76016e-09 (rank : 24)	NC score	0.677348 (rank : 18)
Query Neighborhood Hits	57	Target Neighborhood Hits	46	Shared Neighborhood Hits	41
SwissProt Accessions	Q99757, Q5JZA0, Q9UH29	Gene names	TXN2, TRX2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

THIOM_MOUSE
θ value	6.21693e-09 (rank : 25)	NC score	0.672758 (rank : 19)
Query Neighborhood Hits	57	Target Neighborhood Hits	45	Shared Neighborhood Hits	40
SwissProt Accessions	P97493, Q545D5	Gene names	Txn2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

QSC6L_HUMAN
θ value	4.92598e-06 (rank : 26)	NC score	0.477923 (rank : 27)
Query Neighborhood Hits	57	Target Neighborhood Hits	35	Shared Neighborhood Hits	30
SwissProt Accessions	Q6ZRP7, Q5TB37, Q7Z7B6, Q86VV7, Q8N3G2	Gene names	QSCN6L1, QSOX2, SOXN
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 2 precursor (EC 1.8.3.2) (Quiescin Q6-like protein 1) (Neuroblastoma-derived sulfhydryl oxidase).

QSC6L_MOUSE
θ value	6.43352e-06 (rank : 27)	NC score	0.448957 (rank : 28)
Query Neighborhood Hits	57	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	Q3TMX7, Q3TZA5, Q8C9I4, Q8K0M2	Gene names	Qscn6l1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 2 precursor (EC 1.8.3.2) (Quiescin Q6-like protein 1).

THIO_HUMAN
θ value	4.1701e-05 (rank : 28)	NC score	0.523023 (rank : 23)
Query Neighborhood Hits	57	Target Neighborhood Hits	43	Shared Neighborhood Hits	38
SwissProt Accessions	P10599, Q96KI3	Gene names	TXN, TRDX, TRX, TRX1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP).

TXND8_MOUSE
θ value	0.000158464 (rank : 29)	NC score	0.537242 (rank : 22)
Query Neighborhood Hits	57	Target Neighborhood Hits	41	Shared Neighborhood Hits	38
SwissProt Accessions	Q69AB2, Q78Y03, Q80YE0, Q9CQ96	Gene names	Txndc8, Sptrx3, Trx6
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6).

THIO_MOUSE
θ value	0.00035302 (rank : 30)	NC score	0.486626 (rank : 26)
Query Neighborhood Hits	57	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	P10639, Q52KC4, Q9D8R0	Gene names	Txn, Txn1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF).

TXNL2_MOUSE
θ value	0.00035302 (rank : 31)	NC score	0.368575 (rank : 31)
Query Neighborhood Hits	57	Target Neighborhood Hits	54	Shared Neighborhood Hits	36
SwissProt Accessions	Q9CQM9, Q9JLZ2	Gene names	Txnl2, Picot
Domain Architecture
Description	Thioredoxin-like protein 2 (PKC-interacting cousin of thioredoxin) (PKC-theta-interacting protein) (PKCq-interacting protein).

TXND2_MOUSE
θ value	0.00134147 (rank : 32)	NC score	0.223437 (rank : 39)
Query Neighborhood Hits	57	Target Neighborhood Hits	828	Shared Neighborhood Hits	41
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

TXNL2_HUMAN
θ value	0.00228821 (rank : 33)	NC score	0.363354 (rank : 32)
Query Neighborhood Hits	57	Target Neighborhood Hits	59	Shared Neighborhood Hits	37
SwissProt Accessions	O76003, Q96CE0, Q9P1B0, Q9P1B1	Gene names	TXNL2, PICOT
Domain Architecture
Description	Thioredoxin-like protein 2 (PKC-interacting cousin of thioredoxin) (PKC-theta-interacting protein) (PKCq-interacting protein).

TXND2_HUMAN
θ value	0.00298849 (rank : 34)	NC score	0.211608 (rank : 41)
Query Neighborhood Hits	57	Target Neighborhood Hits	793	Shared Neighborhood Hits	36
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

TXND3_HUMAN
θ value	0.00509761 (rank : 35)	NC score	0.185618 (rank : 44)
Query Neighborhood Hits	57	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N427, Q9NZH1	Gene names	TXNDC3, NME8, SPTRX2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2) (NM23-H8).

TXNL1_HUMAN
θ value	0.00509761 (rank : 36)	NC score	0.250547 (rank : 36)
Query Neighborhood Hits	57	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	O43396	Gene names	TXNL1, TRP32, TXL, TXNL
Domain Architecture
Description	Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein).

TXNL1_MOUSE
θ value	0.00509761 (rank : 37)	NC score	0.249224 (rank : 37)
Query Neighborhood Hits	57	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CDN6, O70379, Q3TI92	Gene names	Txnl1, Trp32, Txnl
Domain Architecture	No domain graphic available
Description	Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein).

TXD13_HUMAN
θ value	0.0961366 (rank : 38)	NC score	0.348931 (rank : 34)
Query Neighborhood Hits	57	Target Neighborhood Hits	106	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H1E5, Q8N4P7, Q8NCC1, Q9UJA1, Q9ULQ8	Gene names	TXNDC13, KIAA1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

CASQ1_HUMAN
θ value	0.125558 (rank : 39)	NC score	0.224796 (rank : 38)
Query Neighborhood Hits	57	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	P31415, Q8TBW7	Gene names	CASQ1, CASQ
Domain Architecture
Description	Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform) (Calmitin).

TXND3_MOUSE
θ value	0.125558 (rank : 40)	NC score	0.118336 (rank : 47)
Query Neighborhood Hits	57	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	Q715T0, Q80W74	Gene names	Txndc3, Sptrx2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2).

TXD13_MOUSE
θ value	0.163984 (rank : 41)	NC score	0.352829 (rank : 33)
Query Neighborhood Hits	57	Target Neighborhood Hits	61	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C0L0, Q3UHC6, Q6ZPW7, Q80X49	Gene names	Txndc13, D2Bwg1356e, Kiaa1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

CASQ2_HUMAN
θ value	0.279714 (rank : 42)	NC score	0.216094 (rank : 40)
Query Neighborhood Hits	57	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	O14958, Q8TBW8	Gene names	CASQ2
Domain Architecture
Description	Calsequestrin-2 precursor (Calsequestrin, cardiac muscle isoform).

DIAP1_HUMAN
θ value	0.279714 (rank : 43)	NC score	0.029373 (rank : 51)
Query Neighborhood Hits	57	Target Neighborhood Hits	784	Shared Neighborhood Hits	7
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

TXD12_HUMAN
θ value	0.279714 (rank : 44)	NC score	0.123239 (rank : 46)
Query Neighborhood Hits	57	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	O95881, Q5T1T4, Q96H50	Gene names	TXNDC12, TLP19
Domain Architecture
Description	Thioredoxin domain-containing protein 12 precursor (EC 1.8.4.2) (Thioredoxin-like protein p19) (Endoplasmic reticulum protein ERp19) (ERp18) (hTLP19).

NUF2_MOUSE
θ value	0.365318 (rank : 45)	NC score	0.019331 (rank : 53)
Query Neighborhood Hits	57	Target Neighborhood Hits	585	Shared Neighborhood Hits	8
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

TXD12_MOUSE
θ value	0.47712 (rank : 46)	NC score	0.116816 (rank : 48)
Query Neighborhood Hits	57	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CQU0, Q53YN1	Gene names	Txndc12, Tlp19
Domain Architecture
Description	Thioredoxin domain-containing protein 12 precursor (EC 1.8.4.2) (Thioredoxin-like protein p19) (Endoplasmic reticulum protein ERp19).

TXND8_HUMAN
θ value	0.47712 (rank : 47)	NC score	0.312372 (rank : 35)
Query Neighborhood Hits	57	Target Neighborhood Hits	27	Shared Neighborhood Hits	26
SwissProt Accessions	Q6A555, Q5T934	Gene names	TXNDC8, SPTRX3, TRX6
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6).

DIAP1_MOUSE
θ value	0.62314 (rank : 48)	NC score	0.027133 (rank : 52)
Query Neighborhood Hits	57	Target Neighborhood Hits	839	Shared Neighborhood Hits	7
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

CASQ1_MOUSE
θ value	0.813845 (rank : 49)	NC score	0.207330 (rank : 42)
Query Neighborhood Hits	57	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	O09165	Gene names	Casq1
Domain Architecture
Description	Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform).

DDX52_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.002817 (rank : 57)
Query Neighborhood Hits	57	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

DJC16_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.036697 (rank : 50)
Query Neighborhood Hits	57	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2G8, Q68D57, Q86X32, Q8N5P4	Gene names	DNAJC16, KIAA0962
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 16 precursor.

CE152_HUMAN
θ value	6.88961 (rank : 52)	NC score	0.005014 (rank : 56)
Query Neighborhood Hits	57	Target Neighborhood Hits	976	Shared Neighborhood Hits	8
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CJ084_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.013291 (rank : 55)
Query Neighborhood Hits	57	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H8W3, Q9H5V5	Gene names	C10orf84
Domain Architecture	No domain graphic available
Description	Protein C10orf84.

MCFD2_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.018585 (rank : 54)
Query Neighborhood Hits	57	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NI22, Q8N3M5	Gene names	MCFD2, SDNSF
Domain Architecture
Description	Multiple coagulation factor deficiency protein 2 precursor (Neural stem cell-derived neuronal survival protein).

AKAP9_HUMAN
θ value	8.99809 (rank : 55)	NC score	0.000541 (rank : 59)
Query Neighborhood Hits	57	Target Neighborhood Hits	1710	Shared Neighborhood Hits	8
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

EHMT1_HUMAN
θ value	8.99809 (rank : 56)	NC score	0.001962 (rank : 58)
Query Neighborhood Hits	57	Target Neighborhood Hits	417	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

TXND6_HUMAN
θ value	8.99809 (rank : 57)	NC score	0.155511 (rank : 45)
Query Neighborhood Hits	57	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	Q86XW9, Q7Z4A8, Q8N1V7	Gene names	TXNDC6, TXL2
Domain Architecture
Description	Thioredoxin domain-containing protein 6 (Thioredoxin-like protein 2) (Txl-2).

CASQ2_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.195044 (rank : 43)
Query Neighborhood Hits	57	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	O09161, O88505	Gene names	Casq2
Domain Architecture
Description	Calsequestrin-2 precursor (Calsequestrin, cardiac muscle isoform).

ERP29_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.050650 (rank : 49)
Query Neighborhood Hits	57	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	P30040, Q6FHT4	Gene names	ERP29, C12orf8, ERP28
Domain Architecture
Description	Endoplasmic reticulum protein ERp29 precursor (ERp31) (ERp28).

Hits sorted by NC score

PDIA3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	57	Target Neighborhood Hits	57	Shared Neighborhood Hits	57
SwissProt Accessions	P30101, Q13453, Q14255, Q8IYF8, Q9UMU7	Gene names	PDIA3, ERP60, GRP58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57) (58 kDa glucose-regulated protein).

PDIA3_MOUSE
NC score	0.998436 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	57	Target Neighborhood Hits	58	Shared Neighborhood Hits	52
SwissProt Accessions	P27773	Gene names	Pdia3, Erp, Erp60, Grp58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57).

PDIA4_MOUSE
NC score	0.953166 (rank : 3)	θ value	6.27148e-94 (rank : 4)
Query Neighborhood Hits	57	Target Neighborhood Hits	57	Shared Neighborhood Hits	45
SwissProt Accessions	P08003, P15841	Gene names	Pdia4, Cai, Erp72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

PDIA4_HUMAN
NC score	0.952521 (rank : 4)	θ value	5.67233e-95 (rank : 3)
Query Neighborhood Hits	57	Target Neighborhood Hits	60	Shared Neighborhood Hits	45
SwissProt Accessions	P13667	Gene names	PDIA4, ERP70, ERP72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

PDIA1_HUMAN
NC score	0.935492 (rank : 5)	θ value	1.2325e-65 (rank : 6)
Query Neighborhood Hits	57	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	P07237, P30037, P32079, Q15205, Q6LDE5	Gene names	P4HB, PDI, PDIA1, PO4DB
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55).

PDIA1_MOUSE
NC score	0.931841 (rank : 6)	θ value	1.11475e-66 (rank : 5)
Query Neighborhood Hits	57	Target Neighborhood Hits	50	Shared Neighborhood Hits	44
SwissProt Accessions	P09103	Gene names	P4hb, Pdia1
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55) (Erp59).

PDIA2_HUMAN
NC score	0.927182 (rank : 7)	θ value	2.66562e-52 (rank : 7)
Query Neighborhood Hits	57	Target Neighborhood Hits	49	Shared Neighborhood Hits	41
SwissProt Accessions	Q13087, Q96KJ6, Q9BW95	Gene names	PDIA2, PDIP
Domain Architecture
Description	Protein disulfide-isomerase A2 precursor (EC 5.3.4.1) (PDIp).

PDIA6_HUMAN
NC score	0.827577 (rank : 8)	θ value	5.23862e-24 (rank : 9)
Query Neighborhood Hits	57	Target Neighborhood Hits	46	Shared Neighborhood Hits	42
SwissProt Accessions	Q15084, Q99778	Gene names	PDIA6, TXNDC7
Domain Architecture
Description	Protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7).

PDIA6_MOUSE
NC score	0.825619 (rank : 9)	θ value	8.08199e-25 (rank : 8)
Query Neighborhood Hits	57	Target Neighborhood Hits	47	Shared Neighborhood Hits	44
SwissProt Accessions	Q922R8, Q8BK54	Gene names	Pdia6, Txndc7
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 7).

TXND5_MOUSE
NC score	0.820265 (rank : 10)	θ value	5.79196e-23 (rank : 10)
Query Neighborhood Hits	57	Target Neighborhood Hits	52	Shared Neighborhood Hits	44
SwissProt Accessions	Q91W90, Q8R1I6	Gene names	Txndc5, Tlp46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46) (Plasma cell- specific thioredoxin-related protein) (PC-TRP).

TXND5_HUMAN
NC score	0.816032 (rank : 11)	θ value	1.86321e-21 (rank : 11)
Query Neighborhood Hits	57	Target Neighborhood Hits	54	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NBS9, Q8ND33, Q8TCT2, Q9BVH9	Gene names	TXNDC5, TLP46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46).

TXD10_MOUSE
NC score	0.760742 (rank : 12)	θ value	1.47631e-18 (rank : 12)
Query Neighborhood Hits	57	Target Neighborhood Hits	48	Shared Neighborhood Hits	42
SwissProt Accessions	Q8BXZ1, Q3US84, Q6PGA1, Q6ZPH5, Q8BZB8	Gene names	Txndc10, Kiaa1830
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase TXNDC10 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 10).

TXD10_HUMAN
NC score	0.757717 (rank : 13)	θ value	2.5182e-18 (rank : 13)
Query Neighborhood Hits	57	Target Neighborhood Hits	47	Shared Neighborhood Hits	41
SwissProt Accessions	Q96JJ7, Q8N5J0, Q9NWJ9	Gene names	TXNDC10, KIAA1830, TMX3
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase TXNDC10 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 10) (Thioredoxin-related transmembrane protein 3).

PDIA5_MOUSE
NC score	0.745988 (rank : 14)	θ value	3.76295e-14 (rank : 16)
Query Neighborhood Hits	57	Target Neighborhood Hits	46	Shared Neighborhood Hits	43
SwissProt Accessions	Q921X9	Gene names	Pdia5, Pdir
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

PDIA5_HUMAN
NC score	0.744954 (rank : 15)	θ value	1.42992e-13 (rank : 17)
Query Neighborhood Hits	57	Target Neighborhood Hits	42	Shared Neighborhood Hits	40
SwissProt Accessions	Q14554	Gene names	PDIA5, PDIR
Domain Architecture
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

TXND4_HUMAN
NC score	0.731577 (rank : 16)	θ value	5.25075e-16 (rank : 15)
Query Neighborhood Hits	57	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BS26, O60319, Q5VWZ7, Q6UW14, Q8WX67	Gene names	TXNDC4, ERP44, KIAA0573
Domain Architecture
Description	Thioredoxin domain-containing protein 4 precursor (Endoplasmic reticulum resident protein ERp44).

TXND4_MOUSE
NC score	0.727193 (rank : 17)	θ value	1.80466e-16 (rank : 14)
Query Neighborhood Hits	57	Target Neighborhood Hits	44	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D1Q6, Q3TVI1, Q6A045	Gene names	Txndc4, Erp44, Kiaa0573
Domain Architecture
Description	Thioredoxin domain-containing protein 4 precursor (Endoplasmic reticulum resident protein ERp44).

THIOM_HUMAN
NC score	0.677348 (rank : 18)	θ value	4.76016e-09 (rank : 24)
Query Neighborhood Hits	57	Target Neighborhood Hits	46	Shared Neighborhood Hits	41
SwissProt Accessions	Q99757, Q5JZA0, Q9UH29	Gene names	TXN2, TRX2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

THIOM_MOUSE
NC score	0.672758 (rank : 19)	θ value	6.21693e-09 (rank : 25)
Query Neighborhood Hits	57	Target Neighborhood Hits	45	Shared Neighborhood Hits	40
SwissProt Accessions	P97493, Q545D5	Gene names	Txn2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

TXND1_HUMAN
NC score	0.622282 (rank : 20)	θ value	7.34386e-10 (rank : 20)
Query Neighborhood Hits	57	Target Neighborhood Hits	38	Shared Neighborhood Hits	37
SwissProt Accessions	Q9H3N1, Q8N487, Q8NBN5, Q9Y4T6	Gene names	TXNDC1, TMX, TXNDC
Domain Architecture
Description	Thioredoxin domain-containing protein 1 precursor (Transmembrane Trx- related protein) (Thioredoxin-related transmembrane protein).

TXND1_MOUSE
NC score	0.605522 (rank : 21)	θ value	2.13673e-09 (rank : 21)
Query Neighborhood Hits	57	Target Neighborhood Hits	36	Shared Neighborhood Hits	34
SwissProt Accessions	Q8VBT0, Q3UCI8, Q9CSD5	Gene names	Txndc1, Txndc
Domain Architecture
Description	Thioredoxin domain-containing protein 1 precursor.

TXND8_MOUSE
NC score	0.537242 (rank : 22)	θ value	0.000158464 (rank : 29)
Query Neighborhood Hits	57	Target Neighborhood Hits	41	Shared Neighborhood Hits	38
SwissProt Accessions	Q69AB2, Q78Y03, Q80YE0, Q9CQ96	Gene names	Txndc8, Sptrx3, Trx6
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6).

THIO_HUMAN
NC score	0.523023 (rank : 23)	θ value	4.1701e-05 (rank : 28)
Query Neighborhood Hits	57	Target Neighborhood Hits	43	Shared Neighborhood Hits	38
SwissProt Accessions	P10599, Q96KI3	Gene names	TXN, TRDX, TRX, TRX1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP).

QSCN6_MOUSE
NC score	0.512544 (rank : 24)	θ value	4.30538e-10 (rank : 19)
Query Neighborhood Hits	57	Target Neighborhood Hits	62	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BND5, Q3TDY9, Q3TE19, Q3TR29, Q3UEL4, Q8K041, Q9DBL6	Gene names	Qscn6, Sox
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (Skin sulfhydryl oxidase) (mSOx).

QSCN6_HUMAN
NC score	0.492470 (rank : 25)	θ value	4.76016e-09 (rank : 23)
Query Neighborhood Hits	57	Target Neighborhood Hits	98	Shared Neighborhood Hits	32
SwissProt Accessions	O00391, Q59G29, Q5T2X0, Q8TDL6, Q8WVP4	Gene names	QSCN6, QSOX1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (hQSOX).

THIO_MOUSE
NC score	0.486626 (rank : 26)	θ value	0.00035302 (rank : 30)
Query Neighborhood Hits	57	Target Neighborhood Hits	39	Shared Neighborhood Hits	36
SwissProt Accessions	P10639, Q52KC4, Q9D8R0	Gene names	Txn, Txn1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF).

QSC6L_HUMAN
NC score	0.477923 (rank : 27)	θ value	4.92598e-06 (rank : 26)
Query Neighborhood Hits	57	Target Neighborhood Hits	35	Shared Neighborhood Hits	30
SwissProt Accessions	Q6ZRP7, Q5TB37, Q7Z7B6, Q86VV7, Q8N3G2	Gene names	QSCN6L1, QSOX2, SOXN
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 2 precursor (EC 1.8.3.2) (Quiescin Q6-like protein 1) (Neuroblastoma-derived sulfhydryl oxidase).

QSC6L_MOUSE
NC score	0.448957 (rank : 28)	θ value	6.43352e-06 (rank : 27)
Query Neighborhood Hits	57	Target Neighborhood Hits	36	Shared Neighborhood Hits	25
SwissProt Accessions	Q3TMX7, Q3TZA5, Q8C9I4, Q8K0M2	Gene names	Qscn6l1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 2 precursor (EC 1.8.3.2) (Quiescin Q6-like protein 1).

TXD11_MOUSE
NC score	0.417199 (rank : 29)	θ value	3.64472e-09 (rank : 22)
Query Neighborhood Hits	57	Target Neighborhood Hits	81	Shared Neighborhood Hits	25
SwissProt Accessions	Q8K2W3, Q8BMR8, Q8VCK9	Gene names	Txndc11
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11.

TXD11_HUMAN
NC score	0.385160 (rank : 30)	θ value	3.29651e-10 (rank : 18)
Query Neighborhood Hits	57	Target Neighborhood Hits	402	Shared Neighborhood Hits	32
SwissProt Accessions	Q6PKC3, O95887, Q6PJA6, Q8N2Q4, Q96K45, Q96K53	Gene names	TXNDC11, EFP1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1).

TXNL2_MOUSE
NC score	0.368575 (rank : 31)	θ value	0.00035302 (rank : 31)
Query Neighborhood Hits	57	Target Neighborhood Hits	54	Shared Neighborhood Hits	36
SwissProt Accessions	Q9CQM9, Q9JLZ2	Gene names	Txnl2, Picot
Domain Architecture
Description	Thioredoxin-like protein 2 (PKC-interacting cousin of thioredoxin) (PKC-theta-interacting protein) (PKCq-interacting protein).

TXNL2_HUMAN
NC score	0.363354 (rank : 32)	θ value	0.00228821 (rank : 33)
Query Neighborhood Hits	57	Target Neighborhood Hits	59	Shared Neighborhood Hits	37
SwissProt Accessions	O76003, Q96CE0, Q9P1B0, Q9P1B1	Gene names	TXNL2, PICOT
Domain Architecture
Description	Thioredoxin-like protein 2 (PKC-interacting cousin of thioredoxin) (PKC-theta-interacting protein) (PKCq-interacting protein).

TXD13_MOUSE
NC score	0.352829 (rank : 33)	θ value	0.163984 (rank : 41)
Query Neighborhood Hits	57	Target Neighborhood Hits	61	Shared Neighborhood Hits	24
SwissProt Accessions	Q8C0L0, Q3UHC6, Q6ZPW7, Q80X49	Gene names	Txndc13, D2Bwg1356e, Kiaa1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

TXD13_HUMAN
NC score	0.348931 (rank : 34)	θ value	0.0961366 (rank : 38)
Query Neighborhood Hits	57	Target Neighborhood Hits	106	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H1E5, Q8N4P7, Q8NCC1, Q9UJA1, Q9ULQ8	Gene names	TXNDC13, KIAA1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

TXND8_HUMAN
NC score	0.312372 (rank : 35)	θ value	0.47712 (rank : 47)
Query Neighborhood Hits	57	Target Neighborhood Hits	27	Shared Neighborhood Hits	26
SwissProt Accessions	Q6A555, Q5T934	Gene names	TXNDC8, SPTRX3, TRX6
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6).

TXNL1_HUMAN
NC score	0.250547 (rank : 36)	θ value	0.00509761 (rank : 36)
Query Neighborhood Hits	57	Target Neighborhood Hits	30	Shared Neighborhood Hits	25
SwissProt Accessions	O43396	Gene names	TXNL1, TRP32, TXL, TXNL
Domain Architecture
Description	Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein).

TXNL1_MOUSE
NC score	0.249224 (rank : 37)	θ value	0.00509761 (rank : 37)
Query Neighborhood Hits	57	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CDN6, O70379, Q3TI92	Gene names	Txnl1, Trp32, Txnl
Domain Architecture	No domain graphic available
Description	Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein).

CASQ1_HUMAN
NC score	0.224796 (rank : 38)	θ value	0.125558 (rank : 39)
Query Neighborhood Hits	57	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	P31415, Q8TBW7	Gene names	CASQ1, CASQ
Domain Architecture
Description	Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform) (Calmitin).

TXND2_MOUSE
NC score	0.223437 (rank : 39)	θ value	0.00134147 (rank : 32)
Query Neighborhood Hits	57	Target Neighborhood Hits	828	Shared Neighborhood Hits	41
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

CASQ2_HUMAN
NC score	0.216094 (rank : 40)	θ value	0.279714 (rank : 42)
Query Neighborhood Hits	57	Target Neighborhood Hits	20	Shared Neighborhood Hits	12
SwissProt Accessions	O14958, Q8TBW8	Gene names	CASQ2
Domain Architecture
Description	Calsequestrin-2 precursor (Calsequestrin, cardiac muscle isoform).

TXND2_HUMAN
NC score	0.211608 (rank : 41)	θ value	0.00298849 (rank : 34)
Query Neighborhood Hits	57	Target Neighborhood Hits	793	Shared Neighborhood Hits	36
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

CASQ1_MOUSE
NC score	0.207330 (rank : 42)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	57	Target Neighborhood Hits	24	Shared Neighborhood Hits	16
SwissProt Accessions	O09165	Gene names	Casq1
Domain Architecture
Description	Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform).

CASQ2_MOUSE
NC score	0.195044 (rank : 43)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	57	Target Neighborhood Hits	34	Shared Neighborhood Hits	11
SwissProt Accessions	O09161, O88505	Gene names	Casq2
Domain Architecture
Description	Calsequestrin-2 precursor (Calsequestrin, cardiac muscle isoform).

TXND3_HUMAN
NC score	0.185618 (rank : 44)	θ value	0.00509761 (rank : 35)
Query Neighborhood Hits	57	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N427, Q9NZH1	Gene names	TXNDC3, NME8, SPTRX2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2) (NM23-H8).

TXND6_HUMAN
NC score	0.155511 (rank : 45)	θ value	8.99809 (rank : 57)
Query Neighborhood Hits	57	Target Neighborhood Hits	46	Shared Neighborhood Hits	27
SwissProt Accessions	Q86XW9, Q7Z4A8, Q8N1V7	Gene names	TXNDC6, TXL2
Domain Architecture
Description	Thioredoxin domain-containing protein 6 (Thioredoxin-like protein 2) (Txl-2).

TXD12_HUMAN
NC score	0.123239 (rank : 46)	θ value	0.279714 (rank : 44)
Query Neighborhood Hits	57	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	O95881, Q5T1T4, Q96H50	Gene names	TXNDC12, TLP19
Domain Architecture
Description	Thioredoxin domain-containing protein 12 precursor (EC 1.8.4.2) (Thioredoxin-like protein p19) (Endoplasmic reticulum protein ERp19) (ERp18) (hTLP19).

TXND3_MOUSE
NC score	0.118336 (rank : 47)	θ value	0.125558 (rank : 40)
Query Neighborhood Hits	57	Target Neighborhood Hits	51	Shared Neighborhood Hits	22
SwissProt Accessions	Q715T0, Q80W74	Gene names	Txndc3, Sptrx2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2).

TXD12_MOUSE
NC score	0.116816 (rank : 48)	θ value	0.47712 (rank : 46)
Query Neighborhood Hits	57	Target Neighborhood Hits	18	Shared Neighborhood Hits	12
SwissProt Accessions	Q9CQU0, Q53YN1	Gene names	Txndc12, Tlp19
Domain Architecture
Description	Thioredoxin domain-containing protein 12 precursor (EC 1.8.4.2) (Thioredoxin-like protein p19) (Endoplasmic reticulum protein ERp19).

ERP29_HUMAN
NC score	0.050650 (rank : 49)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	57	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	P30040, Q6FHT4	Gene names	ERP29, C12orf8, ERP28
Domain Architecture
Description	Endoplasmic reticulum protein ERp29 precursor (ERp31) (ERp28).

DJC16_HUMAN
NC score	0.036697 (rank : 50)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	57	Target Neighborhood Hits	100	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2G8, Q68D57, Q86X32, Q8N5P4	Gene names	DNAJC16, KIAA0962
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 16 precursor.

DIAP1_HUMAN
NC score	0.029373 (rank : 51)	θ value	0.279714 (rank : 43)
Query Neighborhood Hits	57	Target Neighborhood Hits	784	Shared Neighborhood Hits	7
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DIAP1_MOUSE
NC score	0.027133 (rank : 52)	θ value	0.62314 (rank : 48)
Query Neighborhood Hits	57	Target Neighborhood Hits	839	Shared Neighborhood Hits	7
SwissProt Accessions	O08808	Gene names	Diaph1, Diap1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1) (mDIA1) (p140mDIA).

NUF2_MOUSE
NC score	0.019331 (rank : 53)	θ value	0.365318 (rank : 45)
Query Neighborhood Hits	57	Target Neighborhood Hits	585	Shared Neighborhood Hits	8
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

MCFD2_HUMAN
NC score	0.018585 (rank : 54)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	57	Target Neighborhood Hits	62	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NI22, Q8N3M5	Gene names	MCFD2, SDNSF
Domain Architecture
Description	Multiple coagulation factor deficiency protein 2 precursor (Neural stem cell-derived neuronal survival protein).

CJ084_HUMAN
NC score	0.013291 (rank : 55)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	57	Target Neighborhood Hits	31	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H8W3, Q9H5V5	Gene names	C10orf84
Domain Architecture	No domain graphic available
Description	Protein C10orf84.

CE152_HUMAN
NC score	0.005014 (rank : 56)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	57	Target Neighborhood Hits	976	Shared Neighborhood Hits	8
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

DDX52_HUMAN
NC score	0.002817 (rank : 57)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	57	Target Neighborhood Hits	107	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2R4, Q86YG1, Q8N213, Q9NVE0, Q9Y482	Gene names	DDX52, ROK1
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.1.-) (DEAD box protein 52) (ATP-dependent RNA helicase ROK1-like).

EHMT1_HUMAN
NC score	0.001962 (rank : 58)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	57	Target Neighborhood Hits	417	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

AKAP9_HUMAN
NC score	0.000541 (rank : 59)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	57	Target Neighborhood Hits	1710	Shared Neighborhood Hits	8
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).