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Network neighborhood for query Sequence : CASQ1_HUMAN

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CASQ1_HUMAN
SwissProt Accessions	P31415, Q8TBW7	Gene names	CASQ1, CASQ
Domain Architecture
Description	Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform) (Calmitin).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CASQ1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	P31415, Q8TBW7	Gene names	CASQ1, CASQ
Domain Architecture
Description	Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform) (Calmitin).

CASQ1_MOUSE
θ value	0 (rank : 2)	NC score	0.998860 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	24	Shared Neighborhood Hits	19
SwissProt Accessions	O09165	Gene names	Casq1
Domain Architecture
Description	Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform).

CASQ2_MOUSE
θ value	1.08919e-146 (rank : 3)	NC score	0.984586 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	O09161, O88505	Gene names	Casq2
Domain Architecture
Description	Calsequestrin-2 precursor (Calsequestrin, cardiac muscle isoform).

CASQ2_HUMAN
θ value	2.05413e-145 (rank : 4)	NC score	0.989743 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	O14958, Q8TBW8	Gene names	CASQ2
Domain Architecture
Description	Calsequestrin-2 precursor (Calsequestrin, cardiac muscle isoform).

TXND4_HUMAN
θ value	1.99992e-07 (rank : 5)	NC score	0.428801 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	43	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BS26, O60319, Q5VWZ7, Q6UW14, Q8WX67	Gene names	TXNDC4, ERP44, KIAA0573
Domain Architecture
Description	Thioredoxin domain-containing protein 4 precursor (Endoplasmic reticulum resident protein ERp44).

PDIA4_HUMAN
θ value	4.45536e-07 (rank : 6)	NC score	0.345058 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	P13667	Gene names	PDIA4, ERP70, ERP72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

TXND4_MOUSE
θ value	5.81887e-07 (rank : 7)	NC score	0.430237 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	44	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D1Q6, Q3TVI1, Q6A045	Gene names	Txndc4, Erp44, Kiaa0573
Domain Architecture
Description	Thioredoxin domain-containing protein 4 precursor (Endoplasmic reticulum resident protein ERp44).

PDIA4_MOUSE
θ value	1.69304e-06 (rank : 8)	NC score	0.336012 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	57	Shared Neighborhood Hits	17
SwissProt Accessions	P08003, P15841	Gene names	Pdia4, Cai, Erp72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

TXD10_HUMAN
θ value	4.92598e-06 (rank : 9)	NC score	0.344106 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	47	Shared Neighborhood Hits	17
SwissProt Accessions	Q96JJ7, Q8N5J0, Q9NWJ9	Gene names	TXNDC10, KIAA1830, TMX3
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase TXNDC10 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 10) (Thioredoxin-related transmembrane protein 3).

PDIA1_MOUSE
θ value	9.29e-05 (rank : 10)	NC score	0.322529 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	50	Shared Neighborhood Hits	17
SwissProt Accessions	P09103	Gene names	P4hb, Pdia1
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55) (Erp59).

PDIA1_HUMAN
θ value	0.000602161 (rank : 11)	NC score	0.301955 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	56	Shared Neighborhood Hits	17
SwissProt Accessions	P07237, P30037, P32079, Q15205, Q6LDE5	Gene names	P4HB, PDI, PDIA1, PO4DB
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55).

TXD10_MOUSE
θ value	0.000786445 (rank : 12)	NC score	0.291225 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	48	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BXZ1, Q3US84, Q6PGA1, Q6ZPH5, Q8BZB8	Gene names	Txndc10, Kiaa1830
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase TXNDC10 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 10).

PDIA3_MOUSE
θ value	0.0431538 (rank : 13)	NC score	0.216734 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	58	Shared Neighborhood Hits	15
SwissProt Accessions	P27773	Gene names	Pdia3, Erp, Erp60, Grp58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57).

PDIA3_HUMAN
θ value	0.125558 (rank : 14)	NC score	0.224796 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	P30101, Q13453, Q14255, Q8IYF8, Q9UMU7	Gene names	PDIA3, ERP60, GRP58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57) (58 kDa glucose-regulated protein).

PDIA6_HUMAN
θ value	1.06291 (rank : 15)	NC score	0.176792 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	46	Shared Neighborhood Hits	15
SwissProt Accessions	Q15084, Q99778	Gene names	PDIA6, TXNDC7
Domain Architecture
Description	Protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7).

PDIA6_MOUSE
θ value	1.38821 (rank : 16)	NC score	0.173824 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	Q922R8, Q8BK54	Gene names	Pdia6, Txndc7
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 7).

SAMN1_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.035152 (rank : 38)
Query Neighborhood Hits	22	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NSI8, Q8NFF7, Q9C041	Gene names	SAMSN1, HACS1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1) (SH3-SAM adaptor protein) (Hematopoietic adaptor containing SH3 and SAM domains 1).

AFAM_HUMAN
θ value	4.03905 (rank : 18)	NC score	0.013077 (rank : 40)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	P43652	Gene names	AFM, ALB2, ALBA
Domain Architecture
Description	Afamin precursor (Alpha-albumin) (Alpha-Alb).

PKHG1_HUMAN
θ value	4.03905 (rank : 19)	NC score	0.010272 (rank : 41)
Query Neighborhood Hits	22	Target Neighborhood Hits	174	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

TXND5_MOUSE
θ value	4.03905 (rank : 20)	NC score	0.156571 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	52	Shared Neighborhood Hits	15
SwissProt Accessions	Q91W90, Q8R1I6	Gene names	Txndc5, Tlp46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46) (Plasma cell- specific thioredoxin-related protein) (PC-TRP).

BMS1_HUMAN
θ value	6.88961 (rank : 21)	NC score	0.017403 (rank : 39)
Query Neighborhood Hits	22	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

SM1L2_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.004432 (rank : 42)
Query Neighborhood Hits	22	Target Neighborhood Hits	918	Shared Neighborhood Hits	3
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

PDIA2_HUMAN
θ value	θ > 10 (rank : 23)	NC score	0.180215 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q13087, Q96KJ6, Q9BW95	Gene names	PDIA2, PDIP
Domain Architecture
Description	Protein disulfide-isomerase A2 precursor (EC 5.3.4.1) (PDIp).

PDIA5_HUMAN
θ value	θ > 10 (rank : 24)	NC score	0.126828 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	42	Shared Neighborhood Hits	13
SwissProt Accessions	Q14554	Gene names	PDIA5, PDIR
Domain Architecture
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

PDIA5_MOUSE
θ value	θ > 10 (rank : 25)	NC score	0.125262 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	Q921X9	Gene names	Pdia5, Pdir
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

QSC6L_HUMAN
θ value	θ > 10 (rank : 26)	NC score	0.066776 (rank : 31)
Query Neighborhood Hits	22	Target Neighborhood Hits	35	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZRP7, Q5TB37, Q7Z7B6, Q86VV7, Q8N3G2	Gene names	QSCN6L1, QSOX2, SOXN
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 2 precursor (EC 1.8.3.2) (Quiescin Q6-like protein 1) (Neuroblastoma-derived sulfhydryl oxidase).

QSC6L_MOUSE
θ value	θ > 10 (rank : 27)	NC score	0.057042 (rank : 33)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	Q3TMX7, Q3TZA5, Q8C9I4, Q8K0M2	Gene names	Qscn6l1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 2 precursor (EC 1.8.3.2) (Quiescin Q6-like protein 1).

QSCN6_HUMAN
θ value	θ > 10 (rank : 28)	NC score	0.067186 (rank : 30)
Query Neighborhood Hits	22	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	O00391, Q59G29, Q5T2X0, Q8TDL6, Q8WVP4	Gene names	QSCN6, QSOX1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (hQSOX).

QSCN6_MOUSE
θ value	θ > 10 (rank : 29)	NC score	0.077237 (rank : 28)
Query Neighborhood Hits	22	Target Neighborhood Hits	62	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BND5, Q3TDY9, Q3TE19, Q3TR29, Q3UEL4, Q8K041, Q9DBL6	Gene names	Qscn6, Sox
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (Skin sulfhydryl oxidase) (mSOx).

THIOM_HUMAN
θ value	θ > 10 (rank : 30)	NC score	0.118878 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	Q99757, Q5JZA0, Q9UH29	Gene names	TXN2, TRX2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

THIOM_MOUSE
θ value	θ > 10 (rank : 31)	NC score	0.118154 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	45	Shared Neighborhood Hits	13
SwissProt Accessions	P97493, Q545D5	Gene names	Txn2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

THIO_HUMAN
θ value	θ > 10 (rank : 32)	NC score	0.079207 (rank : 27)
Query Neighborhood Hits	22	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	P10599, Q96KI3	Gene names	TXN, TRDX, TRX, TRX1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP).

THIO_MOUSE
θ value	θ > 10 (rank : 33)	NC score	0.072410 (rank : 29)
Query Neighborhood Hits	22	Target Neighborhood Hits	39	Shared Neighborhood Hits	13
SwissProt Accessions	P10639, Q52KC4, Q9D8R0	Gene names	Txn, Txn1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF).

TXD11_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.053843 (rank : 35)
Query Neighborhood Hits	22	Target Neighborhood Hits	402	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PKC3, O95887, Q6PJA6, Q8N2Q4, Q96K45, Q96K53	Gene names	TXNDC11, EFP1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1).

TXD11_MOUSE
θ value	θ > 10 (rank : 35)	NC score	0.060889 (rank : 32)
Query Neighborhood Hits	22	Target Neighborhood Hits	81	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K2W3, Q8BMR8, Q8VCK9	Gene names	Txndc11
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11.

TXD13_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.052241 (rank : 36)
Query Neighborhood Hits	22	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H1E5, Q8N4P7, Q8NCC1, Q9UJA1, Q9ULQ8	Gene names	TXNDC13, KIAA1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

TXD13_MOUSE
θ value	θ > 10 (rank : 37)	NC score	0.054894 (rank : 34)
Query Neighborhood Hits	22	Target Neighborhood Hits	61	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C0L0, Q3UHC6, Q6ZPW7, Q80X49	Gene names	Txndc13, D2Bwg1356e, Kiaa1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

TXND1_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.109866 (rank : 24)
Query Neighborhood Hits	22	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H3N1, Q8N487, Q8NBN5, Q9Y4T6	Gene names	TXNDC1, TMX, TXNDC
Domain Architecture
Description	Thioredoxin domain-containing protein 1 precursor (Transmembrane Trx- related protein) (Thioredoxin-related transmembrane protein).

TXND1_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.106644 (rank : 25)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VBT0, Q3UCI8, Q9CSD5	Gene names	Txndc1, Txndc
Domain Architecture
Description	Thioredoxin domain-containing protein 1 precursor.

TXND5_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.145663 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NBS9, Q8ND33, Q8TCT2, Q9BVH9	Gene names	TXNDC5, TLP46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46).

TXND8_MOUSE
θ value	θ > 10 (rank : 41)	NC score	0.083407 (rank : 26)
Query Neighborhood Hits	22	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q69AB2, Q78Y03, Q80YE0, Q9CQ96	Gene names	Txndc8, Sptrx3, Trx6
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6).

TXNL2_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.050900 (rank : 37)
Query Neighborhood Hits	22	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CQM9, Q9JLZ2	Gene names	Txnl2, Picot
Domain Architecture
Description	Thioredoxin-like protein 2 (PKC-interacting cousin of thioredoxin) (PKC-theta-interacting protein) (PKCq-interacting protein).

Hits sorted by NC score

CASQ1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	P31415, Q8TBW7	Gene names	CASQ1, CASQ
Domain Architecture
Description	Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform) (Calmitin).

CASQ1_MOUSE
NC score	0.998860 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	24	Shared Neighborhood Hits	19
SwissProt Accessions	O09165	Gene names	Casq1
Domain Architecture
Description	Calsequestrin-1 precursor (Calsequestrin, skeletal muscle isoform).

CASQ2_HUMAN
NC score	0.989743 (rank : 3)	θ value	2.05413e-145 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	O14958, Q8TBW8	Gene names	CASQ2
Domain Architecture
Description	Calsequestrin-2 precursor (Calsequestrin, cardiac muscle isoform).

CASQ2_MOUSE
NC score	0.984586 (rank : 4)	θ value	1.08919e-146 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	34	Shared Neighborhood Hits	12
SwissProt Accessions	O09161, O88505	Gene names	Casq2
Domain Architecture
Description	Calsequestrin-2 precursor (Calsequestrin, cardiac muscle isoform).

TXND4_MOUSE
NC score	0.430237 (rank : 5)	θ value	5.81887e-07 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	44	Shared Neighborhood Hits	17
SwissProt Accessions	Q9D1Q6, Q3TVI1, Q6A045	Gene names	Txndc4, Erp44, Kiaa0573
Domain Architecture
Description	Thioredoxin domain-containing protein 4 precursor (Endoplasmic reticulum resident protein ERp44).

TXND4_HUMAN
NC score	0.428801 (rank : 6)	θ value	1.99992e-07 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	43	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BS26, O60319, Q5VWZ7, Q6UW14, Q8WX67	Gene names	TXNDC4, ERP44, KIAA0573
Domain Architecture
Description	Thioredoxin domain-containing protein 4 precursor (Endoplasmic reticulum resident protein ERp44).

PDIA4_HUMAN
NC score	0.345058 (rank : 7)	θ value	4.45536e-07 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	P13667	Gene names	PDIA4, ERP70, ERP72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

TXD10_HUMAN
NC score	0.344106 (rank : 8)	θ value	4.92598e-06 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	47	Shared Neighborhood Hits	17
SwissProt Accessions	Q96JJ7, Q8N5J0, Q9NWJ9	Gene names	TXNDC10, KIAA1830, TMX3
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase TXNDC10 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 10) (Thioredoxin-related transmembrane protein 3).

PDIA4_MOUSE
NC score	0.336012 (rank : 9)	θ value	1.69304e-06 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	57	Shared Neighborhood Hits	17
SwissProt Accessions	P08003, P15841	Gene names	Pdia4, Cai, Erp72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

PDIA1_MOUSE
NC score	0.322529 (rank : 10)	θ value	9.29e-05 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	50	Shared Neighborhood Hits	17
SwissProt Accessions	P09103	Gene names	P4hb, Pdia1
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55) (Erp59).

PDIA1_HUMAN
NC score	0.301955 (rank : 11)	θ value	0.000602161 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	56	Shared Neighborhood Hits	17
SwissProt Accessions	P07237, P30037, P32079, Q15205, Q6LDE5	Gene names	P4HB, PDI, PDIA1, PO4DB
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55).

TXD10_MOUSE
NC score	0.291225 (rank : 12)	θ value	0.000786445 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	48	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BXZ1, Q3US84, Q6PGA1, Q6ZPH5, Q8BZB8	Gene names	Txndc10, Kiaa1830
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase TXNDC10 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 10).

PDIA3_HUMAN
NC score	0.224796 (rank : 13)	θ value	0.125558 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	P30101, Q13453, Q14255, Q8IYF8, Q9UMU7	Gene names	PDIA3, ERP60, GRP58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57) (58 kDa glucose-regulated protein).

PDIA3_MOUSE
NC score	0.216734 (rank : 14)	θ value	0.0431538 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	58	Shared Neighborhood Hits	15
SwissProt Accessions	P27773	Gene names	Pdia3, Erp, Erp60, Grp58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57).

PDIA2_HUMAN
NC score	0.180215 (rank : 15)	θ value	θ > 10 (rank : 23)
Query Neighborhood Hits	22	Target Neighborhood Hits	49	Shared Neighborhood Hits	13
SwissProt Accessions	Q13087, Q96KJ6, Q9BW95	Gene names	PDIA2, PDIP
Domain Architecture
Description	Protein disulfide-isomerase A2 precursor (EC 5.3.4.1) (PDIp).

PDIA6_HUMAN
NC score	0.176792 (rank : 16)	θ value	1.06291 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	46	Shared Neighborhood Hits	15
SwissProt Accessions	Q15084, Q99778	Gene names	PDIA6, TXNDC7
Domain Architecture
Description	Protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7).

PDIA6_MOUSE
NC score	0.173824 (rank : 17)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	47	Shared Neighborhood Hits	15
SwissProt Accessions	Q922R8, Q8BK54	Gene names	Pdia6, Txndc7
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 7).

TXND5_MOUSE
NC score	0.156571 (rank : 18)	θ value	4.03905 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	52	Shared Neighborhood Hits	15
SwissProt Accessions	Q91W90, Q8R1I6	Gene names	Txndc5, Tlp46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46) (Plasma cell- specific thioredoxin-related protein) (PC-TRP).

TXND5_HUMAN
NC score	0.145663 (rank : 19)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	22	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NBS9, Q8ND33, Q8TCT2, Q9BVH9	Gene names	TXNDC5, TLP46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46).

PDIA5_HUMAN
NC score	0.126828 (rank : 20)	θ value	θ > 10 (rank : 24)
Query Neighborhood Hits	22	Target Neighborhood Hits	42	Shared Neighborhood Hits	13
SwissProt Accessions	Q14554	Gene names	PDIA5, PDIR
Domain Architecture
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

PDIA5_MOUSE
NC score	0.125262 (rank : 21)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	22	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	Q921X9	Gene names	Pdia5, Pdir
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

THIOM_HUMAN
NC score	0.118878 (rank : 22)	θ value	θ > 10 (rank : 30)
Query Neighborhood Hits	22	Target Neighborhood Hits	46	Shared Neighborhood Hits	13
SwissProt Accessions	Q99757, Q5JZA0, Q9UH29	Gene names	TXN2, TRX2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

THIOM_MOUSE
NC score	0.118154 (rank : 23)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	22	Target Neighborhood Hits	45	Shared Neighborhood Hits	13
SwissProt Accessions	P97493, Q545D5	Gene names	Txn2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

TXND1_HUMAN
NC score	0.109866 (rank : 24)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	22	Target Neighborhood Hits	38	Shared Neighborhood Hits	13
SwissProt Accessions	Q9H3N1, Q8N487, Q8NBN5, Q9Y4T6	Gene names	TXNDC1, TMX, TXNDC
Domain Architecture
Description	Thioredoxin domain-containing protein 1 precursor (Transmembrane Trx- related protein) (Thioredoxin-related transmembrane protein).

TXND1_MOUSE
NC score	0.106644 (rank : 25)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VBT0, Q3UCI8, Q9CSD5	Gene names	Txndc1, Txndc
Domain Architecture
Description	Thioredoxin domain-containing protein 1 precursor.

TXND8_MOUSE
NC score	0.083407 (rank : 26)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	22	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q69AB2, Q78Y03, Q80YE0, Q9CQ96	Gene names	Txndc8, Sptrx3, Trx6
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6).

THIO_HUMAN
NC score	0.079207 (rank : 27)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	22	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	P10599, Q96KI3	Gene names	TXN, TRDX, TRX, TRX1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP).

QSCN6_MOUSE
NC score	0.077237 (rank : 28)	θ value	θ > 10 (rank : 29)
Query Neighborhood Hits	22	Target Neighborhood Hits	62	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BND5, Q3TDY9, Q3TE19, Q3TR29, Q3UEL4, Q8K041, Q9DBL6	Gene names	Qscn6, Sox
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (Skin sulfhydryl oxidase) (mSOx).

THIO_MOUSE
NC score	0.072410 (rank : 29)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	22	Target Neighborhood Hits	39	Shared Neighborhood Hits	13
SwissProt Accessions	P10639, Q52KC4, Q9D8R0	Gene names	Txn, Txn1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF).

QSCN6_HUMAN
NC score	0.067186 (rank : 30)	θ value	θ > 10 (rank : 28)
Query Neighborhood Hits	22	Target Neighborhood Hits	98	Shared Neighborhood Hits	13
SwissProt Accessions	O00391, Q59G29, Q5T2X0, Q8TDL6, Q8WVP4	Gene names	QSCN6, QSOX1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (hQSOX).

QSC6L_HUMAN
NC score	0.066776 (rank : 31)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	22	Target Neighborhood Hits	35	Shared Neighborhood Hits	13
SwissProt Accessions	Q6ZRP7, Q5TB37, Q7Z7B6, Q86VV7, Q8N3G2	Gene names	QSCN6L1, QSOX2, SOXN
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 2 precursor (EC 1.8.3.2) (Quiescin Q6-like protein 1) (Neuroblastoma-derived sulfhydryl oxidase).

TXD11_MOUSE
NC score	0.060889 (rank : 32)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	22	Target Neighborhood Hits	81	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K2W3, Q8BMR8, Q8VCK9	Gene names	Txndc11
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11.

QSC6L_MOUSE
NC score	0.057042 (rank : 33)	θ value	θ > 10 (rank : 27)
Query Neighborhood Hits	22	Target Neighborhood Hits	36	Shared Neighborhood Hits	11
SwissProt Accessions	Q3TMX7, Q3TZA5, Q8C9I4, Q8K0M2	Gene names	Qscn6l1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 2 precursor (EC 1.8.3.2) (Quiescin Q6-like protein 1).

TXD13_MOUSE
NC score	0.054894 (rank : 34)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	22	Target Neighborhood Hits	61	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C0L0, Q3UHC6, Q6ZPW7, Q80X49	Gene names	Txndc13, D2Bwg1356e, Kiaa1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

TXD11_HUMAN
NC score	0.053843 (rank : 35)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	22	Target Neighborhood Hits	402	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PKC3, O95887, Q6PJA6, Q8N2Q4, Q96K45, Q96K53	Gene names	TXNDC11, EFP1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1).

TXD13_HUMAN
NC score	0.052241 (rank : 36)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	22	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H1E5, Q8N4P7, Q8NCC1, Q9UJA1, Q9ULQ8	Gene names	TXNDC13, KIAA1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

TXNL2_MOUSE
NC score	0.050900 (rank : 37)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	22	Target Neighborhood Hits	54	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CQM9, Q9JLZ2	Gene names	Txnl2, Picot
Domain Architecture
Description	Thioredoxin-like protein 2 (PKC-interacting cousin of thioredoxin) (PKC-theta-interacting protein) (PKCq-interacting protein).

SAMN1_HUMAN
NC score	0.035152 (rank : 38)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NSI8, Q8NFF7, Q9C041	Gene names	SAMSN1, HACS1
Domain Architecture
Description	SAM domain-containing protein SAMSN-1 (SAM domain, SH3 domain and nuclear localization signals protein 1) (SH3-SAM adaptor protein) (Hematopoietic adaptor containing SH3 and SAM domains 1).

BMS1_HUMAN
NC score	0.017403 (rank : 39)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q14692, Q86XJ9	Gene names	BMS1L, KIAA0187
Domain Architecture
Description	Ribosome biogenesis protein BMS1 homolog.

AFAM_HUMAN
NC score	0.013077 (rank : 40)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	P43652	Gene names	AFM, ALB2, ALBA
Domain Architecture
Description	Afamin precursor (Alpha-albumin) (Alpha-Alb).

PKHG1_HUMAN
NC score	0.010272 (rank : 41)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	174	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULL1, Q5T1F2	Gene names	PLEKHG1, KIAA1209
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family G member 1.

SM1L2_MOUSE
NC score	0.004432 (rank : 42)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	918	Shared Neighborhood Hits	3
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).