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Network neighborhood for query Sequence : TXND3_MOUSE

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TXND3_MOUSE
SwissProt Accessions	Q715T0, Q80W74	Gene names	Txndc3, Sptrx2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TXND3_HUMAN
θ value	0 (rank : 1)	NC score	0.984788 (rank : 2)
Query Neighborhood Hits	51	Target Neighborhood Hits	70	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N427, Q9NZH1	Gene names	TXNDC3, NME8, SPTRX2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2) (NM23-H8).

TXND3_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	51
SwissProt Accessions	Q715T0, Q80W74	Gene names	Txndc3, Sptrx2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2).

TXND6_HUMAN
θ value	7.03111e-45 (rank : 3)	NC score	0.899340 (rank : 3)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	35
SwissProt Accessions	Q86XW9, Q7Z4A8, Q8N1V7	Gene names	TXNDC6, TXL2
Domain Architecture
Description	Thioredoxin domain-containing protein 6 (Thioredoxin-like protein 2) (Txl-2).

NDK7_HUMAN
θ value	4.73814e-25 (rank : 4)	NC score	0.777914 (rank : 4)
Query Neighborhood Hits	51	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5B8, Q5TGZ4	Gene names	NME7
Domain Architecture
Description	Nucleoside diphosphate kinase 7 (EC 2.7.4.6) (NDK 7) (NDP kinase 7) (nm23-H7).

NDK5_MOUSE
θ value	5.42112e-21 (rank : 5)	NC score	0.762501 (rank : 6)
Query Neighborhood Hits	51	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q99MH5, Q810R1	Gene names	Nme5
Domain Architecture
Description	Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (nm23-M5).

NDK7_MOUSE
θ value	7.0802e-21 (rank : 6)	NC score	0.763462 (rank : 5)
Query Neighborhood Hits	51	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXL8	Gene names	Nme7
Domain Architecture
Description	Nucleoside diphosphate kinase 7 (EC 2.7.4.6) (NDK 7) (NDP kinase 7) (nm23-M7).

NDK5_HUMAN
θ value	1.33526e-19 (rank : 7)	NC score	0.757864 (rank : 7)
Query Neighborhood Hits	51	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	P56597	Gene names	NME5
Domain Architecture
Description	Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (nm23-H5) (Testis-specific nm23 homolog) (Inhibitor of p53-induced apoptosis-beta) (IPIA-beta).

NDK6_HUMAN
θ value	2.28291e-11 (rank : 8)	NC score	0.713121 (rank : 8)
Query Neighborhood Hits	51	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	O75414, Q96E73, Q9BQ63	Gene names	NME6
Domain Architecture
Description	Nucleoside diphosphate kinase 6 (EC 2.7.4.6) (NDK 6) (NDP kinase 6) (nm23-H6) (Inhibitor of p53-induced apoptosis-alpha) (IPIA-alpha).

NDK6_MOUSE
θ value	1.133e-10 (rank : 9)	NC score	0.704433 (rank : 9)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	O88425, Q99M53	Gene names	Nme6
Domain Architecture
Description	Nucleoside diphosphate kinase 6 (EC 2.7.4.6) (NDK 6) (NDP kinase 6) (nm23-M6).

NDKB_HUMAN
θ value	2.79066e-09 (rank : 10)	NC score	0.578333 (rank : 10)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	P22392	Gene names	NME2, NM23B
Domain Architecture
Description	Nucleoside diphosphate kinase B (EC 2.7.4.6) (NDK B) (NDP kinase B) (nm23-H2) (C-myc purine-binding transcription factor PUF).

NDKB_MOUSE
θ value	8.11959e-09 (rank : 11)	NC score	0.576544 (rank : 11)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	Q01768	Gene names	Nme2
Domain Architecture
Description	Nucleoside diphosphate kinase B (EC 2.7.4.6) (NDK B) (NDP kinase B) (nm23-M2) (P18).

NDK8_HUMAN
θ value	3.08544e-08 (rank : 12)	NC score	0.561207 (rank : 14)
Query Neighborhood Hits	51	Target Neighborhood Hits	20	Shared Neighborhood Hits	18
SwissProt Accessions	O60361	Gene names	NME2P1
Domain Architecture
Description	Putative nucleoside diphosphate kinase (EC 2.7.4.6) (NDK) (NDP kinase).

NDK3_MOUSE
θ value	1.17247e-07 (rank : 13)	NC score	0.571153 (rank : 12)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WV85, Q9D931, Q9EPA2	Gene names	Nme3
Domain Architecture
Description	Nucleoside diphosphate kinase 3 (EC 2.7.4.6) (NDK 3) (NDP kinase 3) (Nucleoside diphosphate kinase C) (NDPKC) (nm23-M3) (DR-nm23).

NDKA_HUMAN
θ value	1.69304e-06 (rank : 14)	NC score	0.556051 (rank : 16)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	P15531	Gene names	NME1, NDPKA, NM23
Domain Architecture
Description	Nucleoside diphosphate kinase A (EC 2.7.4.6) (NDK A) (NDP kinase A) (Tumor metastatic process-associated protein) (Metastasis inhibition factor nm23) (nm23-H1) (Granzyme A-activated DNase) (GAAD).

NDKA_MOUSE
θ value	1.69304e-06 (rank : 15)	NC score	0.556689 (rank : 15)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	P15532	Gene names	Nme1, Nm23
Domain Architecture
Description	Nucleoside diphosphate kinase A (EC 2.7.4.6) (NDK A) (NDP kinase A) (Tumor metastatic process-associated protein) (Metastasis inhibition factor NM23) (NDPK-A) (nm23-M1).

NDKM_HUMAN
θ value	2.88788e-06 (rank : 16)	NC score	0.564618 (rank : 13)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	O00746	Gene names	NME4, NM23D
Domain Architecture
Description	Nucleoside diphosphate kinase, mitochondrial precursor (EC 2.7.4.6) (NDP kinase, mitochondrial) (NDK) (nm23-H4) (Nucleoside diphosphate kinase D) (NDPKD).

NDKM_MOUSE
θ value	6.43352e-06 (rank : 17)	NC score	0.553726 (rank : 18)
Query Neighborhood Hits	51	Target Neighborhood Hits	20	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WV84	Gene names	Nme4
Domain Architecture
Description	Nucleoside diphosphate kinase, mitochondrial precursor (EC 2.7.4.6) (NDP kinase, mitochondrial) (NDK) (nm23-M4) (Nucleoside diphosphate kinase D) (NDPKD).

NDK3_HUMAN
θ value	1.09739e-05 (rank : 18)	NC score	0.554319 (rank : 17)
Query Neighborhood Hits	51	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q13232, Q9BWH4	Gene names	NME3
Domain Architecture
Description	Nucleoside diphosphate kinase 3 (EC 2.7.4.6) (NDK 3) (NDP kinase 3) (Nucleoside diphosphate kinase C) (NDPKC) (nm23-H3) (DR-nm23).

THIO_HUMAN
θ value	5.44631e-05 (rank : 19)	NC score	0.293398 (rank : 20)
Query Neighborhood Hits	51	Target Neighborhood Hits	43	Shared Neighborhood Hits	20
SwissProt Accessions	P10599, Q96KI3	Gene names	TXN, TRDX, TRX, TRX1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP).

THIO_MOUSE
θ value	5.44631e-05 (rank : 20)	NC score	0.297995 (rank : 19)
Query Neighborhood Hits	51	Target Neighborhood Hits	39	Shared Neighborhood Hits	20
SwissProt Accessions	P10639, Q52KC4, Q9D8R0	Gene names	Txn, Txn1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF).

TXND2_MOUSE
θ value	0.000786445 (rank : 21)	NC score	0.144545 (rank : 28)
Query Neighborhood Hits	51	Target Neighborhood Hits	828	Shared Neighborhood Hits	23
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

TXNL2_HUMAN
θ value	0.00134147 (rank : 22)	NC score	0.222880 (rank : 21)
Query Neighborhood Hits	51	Target Neighborhood Hits	59	Shared Neighborhood Hits	21
SwissProt Accessions	O76003, Q96CE0, Q9P1B0, Q9P1B1	Gene names	TXNL2, PICOT
Domain Architecture
Description	Thioredoxin-like protein 2 (PKC-interacting cousin of thioredoxin) (PKC-theta-interacting protein) (PKCq-interacting protein).

TXNL2_MOUSE
θ value	0.0431538 (rank : 23)	NC score	0.197467 (rank : 22)
Query Neighborhood Hits	51	Target Neighborhood Hits	54	Shared Neighborhood Hits	20
SwissProt Accessions	Q9CQM9, Q9JLZ2	Gene names	Txnl2, Picot
Domain Architecture
Description	Thioredoxin-like protein 2 (PKC-interacting cousin of thioredoxin) (PKC-theta-interacting protein) (PKCq-interacting protein).

PDIA3_HUMAN
θ value	0.125558 (rank : 24)	NC score	0.118336 (rank : 29)
Query Neighborhood Hits	51	Target Neighborhood Hits	57	Shared Neighborhood Hits	22
SwissProt Accessions	P30101, Q13453, Q14255, Q8IYF8, Q9UMU7	Gene names	PDIA3, ERP60, GRP58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57) (58 kDa glucose-regulated protein).

TXND2_HUMAN
θ value	0.163984 (rank : 25)	NC score	0.112093 (rank : 32)
Query Neighborhood Hits	51	Target Neighborhood Hits	793	Shared Neighborhood Hits	23
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

CEP35_HUMAN
θ value	0.21417 (rank : 26)	NC score	0.047754 (rank : 51)
Query Neighborhood Hits	51	Target Neighborhood Hits	811	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

PDIA3_MOUSE
θ value	0.279714 (rank : 27)	NC score	0.115200 (rank : 31)
Query Neighborhood Hits	51	Target Neighborhood Hits	58	Shared Neighborhood Hits	22
SwissProt Accessions	P27773	Gene names	Pdia3, Erp, Erp60, Grp58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57).

PDIA4_HUMAN
θ value	0.813845 (rank : 28)	NC score	0.104039 (rank : 33)
Query Neighborhood Hits	51	Target Neighborhood Hits	60	Shared Neighborhood Hits	22
SwissProt Accessions	P13667	Gene names	PDIA4, ERP70, ERP72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

TXD11_MOUSE
θ value	0.813845 (rank : 29)	NC score	0.084248 (rank : 38)
Query Neighborhood Hits	51	Target Neighborhood Hits	81	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K2W3, Q8BMR8, Q8VCK9	Gene names	Txndc11
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11.

TXNL1_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.154228 (rank : 27)
Query Neighborhood Hits	51	Target Neighborhood Hits	30	Shared Neighborhood Hits	19
SwissProt Accessions	O43396	Gene names	TXNL1, TRP32, TXL, TXNL
Domain Architecture
Description	Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein).

TXNL1_MOUSE
θ value	0.813845 (rank : 31)	NC score	0.157495 (rank : 25)
Query Neighborhood Hits	51	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CDN6, O70379, Q3TI92	Gene names	Txnl1, Trp32, Txnl
Domain Architecture	No domain graphic available
Description	Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein).

PDIA4_MOUSE
θ value	1.06291 (rank : 32)	NC score	0.101905 (rank : 34)
Query Neighborhood Hits	51	Target Neighborhood Hits	57	Shared Neighborhood Hits	23
SwissProt Accessions	P08003, P15841	Gene names	Pdia4, Cai, Erp72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

TXD11_HUMAN
θ value	1.38821 (rank : 33)	NC score	0.079217 (rank : 40)
Query Neighborhood Hits	51	Target Neighborhood Hits	402	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PKC3, O95887, Q6PJA6, Q8N2Q4, Q96K45, Q96K53	Gene names	TXNDC11, EFP1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1).

FEZ1_MOUSE
θ value	1.81305 (rank : 34)	NC score	0.024993 (rank : 52)
Query Neighborhood Hits	51	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K0X8	Gene names	Fez1
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 1 (Zygin-1) (Zygin I).

THIOM_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.157772 (rank : 24)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	22
SwissProt Accessions	Q99757, Q5JZA0, Q9UH29	Gene names	TXN2, TRX2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

THIOM_MOUSE
θ value	1.81305 (rank : 36)	NC score	0.156964 (rank : 26)
Query Neighborhood Hits	51	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	P97493, Q545D5	Gene names	Txn2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

BICD1_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.011550 (rank : 55)
Query Neighborhood Hits	51	Target Neighborhood Hits	844	Shared Neighborhood Hits	7
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

GHR_MOUSE
θ value	2.36792 (rank : 38)	NC score	0.023825 (rank : 53)
Query Neighborhood Hits	51	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	P16882, P16590, Q61653, Q6DI66, Q80W86, Q8R1M5, Q920Z3, Q9R264	Gene names	Ghr
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

BICD1_MOUSE
θ value	3.0926 (rank : 39)	NC score	0.010418 (rank : 56)
Query Neighborhood Hits	51	Target Neighborhood Hits	837	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

TITIN_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.002288 (rank : 64)
Query Neighborhood Hits	51	Target Neighborhood Hits	2923	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

AR13B_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.008305 (rank : 60)
Query Neighborhood Hits	51	Target Neighborhood Hits	245	Shared Neighborhood Hits	2
SwissProt Accessions	Q640N2	Gene names	Arl13b, Arl2l1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

GABP2_HUMAN
θ value	4.03905 (rank : 42)	NC score	0.008426 (rank : 59)
Query Neighborhood Hits	51	Target Neighborhood Hits	454	Shared Neighborhood Hits	4
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

PDE6C_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.010229 (rank : 57)
Query Neighborhood Hits	51	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P51160, Q5VY29	Gene names	PDE6C, PDEA2
Domain Architecture
Description	Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).

GABP2_MOUSE
θ value	5.27518 (rank : 44)	NC score	0.007912 (rank : 61)
Query Neighborhood Hits	51	Target Neighborhood Hits	429	Shared Neighborhood Hits	4
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

PDIA1_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.083733 (rank : 39)
Query Neighborhood Hits	51	Target Neighborhood Hits	56	Shared Neighborhood Hits	23
SwissProt Accessions	P07237, P30037, P32079, Q15205, Q6LDE5	Gene names	P4HB, PDI, PDIA1, PO4DB
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55).

PADI4_MOUSE
θ value	6.88961 (rank : 46)	NC score	0.007347 (rank : 62)
Query Neighborhood Hits	51	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z183, Q75WC7	Gene names	Padi4, Pdi4
Domain Architecture
Description	Protein-arginine deiminase type-4 (EC 3.5.3.15) (Protein-arginine deiminase type IV) (Peptidylarginine deiminase IV).

TGON2_MOUSE
θ value	6.88961 (rank : 47)	NC score	0.022005 (rank : 54)
Query Neighborhood Hits	51	Target Neighborhood Hits	277	Shared Neighborhood Hits	5
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

TXND5_HUMAN
θ value	6.88961 (rank : 48)	NC score	0.091402 (rank : 36)
Query Neighborhood Hits	51	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NBS9, Q8ND33, Q8TCT2, Q9BVH9	Gene names	TXNDC5, TLP46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46).

DIAP3_HUMAN
θ value	8.99809 (rank : 49)	NC score	0.005527 (rank : 63)
Query Neighborhood Hits	51	Target Neighborhood Hits	209	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

PDE6C_MOUSE
θ value	8.99809 (rank : 50)	NC score	0.008659 (rank : 58)
Query Neighborhood Hits	51	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZQ1, Q8R0D4	Gene names	Pde6c
Domain Architecture	No domain graphic available
Description	Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).

TXND8_MOUSE
θ value	8.99809 (rank : 51)	NC score	0.164537 (rank : 23)
Query Neighborhood Hits	51	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	Q69AB2, Q78Y03, Q80YE0, Q9CQ96	Gene names	Txndc8, Sptrx3, Trx6
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6).

DPY30_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.050572 (rank : 50)
Query Neighborhood Hits	51	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C005	Gene names
Domain Architecture
Description	Dpy-30-like protein.

DPY30_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.050626 (rank : 49)
Query Neighborhood Hits	51	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LT0	Gene names
Domain Architecture
Description	Dpy-30-like protein.

PDIA1_MOUSE
θ value	θ > 10 (rank : 54)	NC score	0.085686 (rank : 37)
Query Neighborhood Hits	51	Target Neighborhood Hits	50	Shared Neighborhood Hits	20
SwissProt Accessions	P09103	Gene names	P4hb, Pdia1
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55) (Erp59).

PDIA2_HUMAN
θ value	θ > 10 (rank : 55)	NC score	0.061438 (rank : 45)
Query Neighborhood Hits	51	Target Neighborhood Hits	49	Shared Neighborhood Hits	19
SwissProt Accessions	Q13087, Q96KJ6, Q9BW95	Gene names	PDIA2, PDIP
Domain Architecture
Description	Protein disulfide-isomerase A2 precursor (EC 5.3.4.1) (PDIp).

PDIA5_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.055605 (rank : 47)
Query Neighborhood Hits	51	Target Neighborhood Hits	42	Shared Neighborhood Hits	18
SwissProt Accessions	Q14554	Gene names	PDIA5, PDIR
Domain Architecture
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

PDIA5_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.067540 (rank : 42)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	Q921X9	Gene names	Pdia5, Pdir
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

PDIA6_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.061629 (rank : 44)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	19
SwissProt Accessions	Q15084, Q99778	Gene names	PDIA6, TXNDC7
Domain Architecture
Description	Protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7).

PDIA6_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.067541 (rank : 41)
Query Neighborhood Hits	51	Target Neighborhood Hits	47	Shared Neighborhood Hits	19
SwissProt Accessions	Q922R8, Q8BK54	Gene names	Pdia6, Txndc7
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 7).

TXD10_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.051062 (rank : 48)
Query Neighborhood Hits	51	Target Neighborhood Hits	47	Shared Neighborhood Hits	18
SwissProt Accessions	Q96JJ7, Q8N5J0, Q9NWJ9	Gene names	TXNDC10, KIAA1830, TMX3
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase TXNDC10 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 10) (Thioredoxin-related transmembrane protein 3).

TXND4_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.061854 (rank : 43)
Query Neighborhood Hits	51	Target Neighborhood Hits	43	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BS26, O60319, Q5VWZ7, Q6UW14, Q8WX67	Gene names	TXNDC4, ERP44, KIAA0573
Domain Architecture
Description	Thioredoxin domain-containing protein 4 precursor (Endoplasmic reticulum resident protein ERp44).

TXND4_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.060477 (rank : 46)
Query Neighborhood Hits	51	Target Neighborhood Hits	44	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D1Q6, Q3TVI1, Q6A045	Gene names	Txndc4, Erp44, Kiaa0573
Domain Architecture
Description	Thioredoxin domain-containing protein 4 precursor (Endoplasmic reticulum resident protein ERp44).

TXND5_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.095563 (rank : 35)
Query Neighborhood Hits	51	Target Neighborhood Hits	52	Shared Neighborhood Hits	21
SwissProt Accessions	Q91W90, Q8R1I6	Gene names	Txndc5, Tlp46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46) (Plasma cell- specific thioredoxin-related protein) (PC-TRP).

TXND8_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.116169 (rank : 30)
Query Neighborhood Hits	51	Target Neighborhood Hits	27	Shared Neighborhood Hits	17
SwissProt Accessions	Q6A555, Q5T934	Gene names	TXNDC8, SPTRX3, TRX6
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6).

Hits sorted by NC score

TXND3_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	51	Target Neighborhood Hits	51	Shared Neighborhood Hits	51
SwissProt Accessions	Q715T0, Q80W74	Gene names	Txndc3, Sptrx2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2).

TXND3_HUMAN
NC score	0.984788 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	51	Target Neighborhood Hits	70	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N427, Q9NZH1	Gene names	TXNDC3, NME8, SPTRX2
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 3 (Spermatid-specific thioredoxin-2) (Sptrx-2) (NM23-H8).

TXND6_HUMAN
NC score	0.899340 (rank : 3)	θ value	7.03111e-45 (rank : 3)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	35
SwissProt Accessions	Q86XW9, Q7Z4A8, Q8N1V7	Gene names	TXNDC6, TXL2
Domain Architecture
Description	Thioredoxin domain-containing protein 6 (Thioredoxin-like protein 2) (Txl-2).

NDK7_HUMAN
NC score	0.777914 (rank : 4)	θ value	4.73814e-25 (rank : 4)
Query Neighborhood Hits	51	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y5B8, Q5TGZ4	Gene names	NME7
Domain Architecture
Description	Nucleoside diphosphate kinase 7 (EC 2.7.4.6) (NDK 7) (NDP kinase 7) (nm23-H7).

NDK7_MOUSE
NC score	0.763462 (rank : 5)	θ value	7.0802e-21 (rank : 6)
Query Neighborhood Hits	51	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXL8	Gene names	Nme7
Domain Architecture
Description	Nucleoside diphosphate kinase 7 (EC 2.7.4.6) (NDK 7) (NDP kinase 7) (nm23-M7).

NDK5_MOUSE
NC score	0.762501 (rank : 6)	θ value	5.42112e-21 (rank : 5)
Query Neighborhood Hits	51	Target Neighborhood Hits	24	Shared Neighborhood Hits	18
SwissProt Accessions	Q99MH5, Q810R1	Gene names	Nme5
Domain Architecture
Description	Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (nm23-M5).

NDK5_HUMAN
NC score	0.757864 (rank : 7)	θ value	1.33526e-19 (rank : 7)
Query Neighborhood Hits	51	Target Neighborhood Hits	28	Shared Neighborhood Hits	18
SwissProt Accessions	P56597	Gene names	NME5
Domain Architecture
Description	Nucleoside diphosphate kinase homolog 5 (NDK-H 5) (NDP kinase homolog 5) (nm23-H5) (Testis-specific nm23 homolog) (Inhibitor of p53-induced apoptosis-beta) (IPIA-beta).

NDK6_HUMAN
NC score	0.713121 (rank : 8)	θ value	2.28291e-11 (rank : 8)
Query Neighborhood Hits	51	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	O75414, Q96E73, Q9BQ63	Gene names	NME6
Domain Architecture
Description	Nucleoside diphosphate kinase 6 (EC 2.7.4.6) (NDK 6) (NDP kinase 6) (nm23-H6) (Inhibitor of p53-induced apoptosis-alpha) (IPIA-alpha).

NDK6_MOUSE
NC score	0.704433 (rank : 9)	θ value	1.133e-10 (rank : 9)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	O88425, Q99M53	Gene names	Nme6
Domain Architecture
Description	Nucleoside diphosphate kinase 6 (EC 2.7.4.6) (NDK 6) (NDP kinase 6) (nm23-M6).

NDKB_HUMAN
NC score	0.578333 (rank : 10)	θ value	2.79066e-09 (rank : 10)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	P22392	Gene names	NME2, NM23B
Domain Architecture
Description	Nucleoside diphosphate kinase B (EC 2.7.4.6) (NDK B) (NDP kinase B) (nm23-H2) (C-myc purine-binding transcription factor PUF).

NDKB_MOUSE
NC score	0.576544 (rank : 11)	θ value	8.11959e-09 (rank : 11)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	Q01768	Gene names	Nme2
Domain Architecture
Description	Nucleoside diphosphate kinase B (EC 2.7.4.6) (NDK B) (NDP kinase B) (nm23-M2) (P18).

NDK3_MOUSE
NC score	0.571153 (rank : 12)	θ value	1.17247e-07 (rank : 13)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WV85, Q9D931, Q9EPA2	Gene names	Nme3
Domain Architecture
Description	Nucleoside diphosphate kinase 3 (EC 2.7.4.6) (NDK 3) (NDP kinase 3) (Nucleoside diphosphate kinase C) (NDPKC) (nm23-M3) (DR-nm23).

NDKM_HUMAN
NC score	0.564618 (rank : 13)	θ value	2.88788e-06 (rank : 16)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	O00746	Gene names	NME4, NM23D
Domain Architecture
Description	Nucleoside diphosphate kinase, mitochondrial precursor (EC 2.7.4.6) (NDP kinase, mitochondrial) (NDK) (nm23-H4) (Nucleoside diphosphate kinase D) (NDPKD).

NDK8_HUMAN
NC score	0.561207 (rank : 14)	θ value	3.08544e-08 (rank : 12)
Query Neighborhood Hits	51	Target Neighborhood Hits	20	Shared Neighborhood Hits	18
SwissProt Accessions	O60361	Gene names	NME2P1
Domain Architecture
Description	Putative nucleoside diphosphate kinase (EC 2.7.4.6) (NDK) (NDP kinase).

NDKA_MOUSE
NC score	0.556689 (rank : 15)	θ value	1.69304e-06 (rank : 15)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	P15532	Gene names	Nme1, Nm23
Domain Architecture
Description	Nucleoside diphosphate kinase A (EC 2.7.4.6) (NDK A) (NDP kinase A) (Tumor metastatic process-associated protein) (Metastasis inhibition factor NM23) (NDPK-A) (nm23-M1).

NDKA_HUMAN
NC score	0.556051 (rank : 16)	θ value	1.69304e-06 (rank : 14)
Query Neighborhood Hits	51	Target Neighborhood Hits	19	Shared Neighborhood Hits	18
SwissProt Accessions	P15531	Gene names	NME1, NDPKA, NM23
Domain Architecture
Description	Nucleoside diphosphate kinase A (EC 2.7.4.6) (NDK A) (NDP kinase A) (Tumor metastatic process-associated protein) (Metastasis inhibition factor nm23) (nm23-H1) (Granzyme A-activated DNase) (GAAD).

NDK3_HUMAN
NC score	0.554319 (rank : 17)	θ value	1.09739e-05 (rank : 18)
Query Neighborhood Hits	51	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q13232, Q9BWH4	Gene names	NME3
Domain Architecture
Description	Nucleoside diphosphate kinase 3 (EC 2.7.4.6) (NDK 3) (NDP kinase 3) (Nucleoside diphosphate kinase C) (NDPKC) (nm23-H3) (DR-nm23).

NDKM_MOUSE
NC score	0.553726 (rank : 18)	θ value	6.43352e-06 (rank : 17)
Query Neighborhood Hits	51	Target Neighborhood Hits	20	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WV84	Gene names	Nme4
Domain Architecture
Description	Nucleoside diphosphate kinase, mitochondrial precursor (EC 2.7.4.6) (NDP kinase, mitochondrial) (NDK) (nm23-M4) (Nucleoside diphosphate kinase D) (NDPKD).

THIO_MOUSE
NC score	0.297995 (rank : 19)	θ value	5.44631e-05 (rank : 20)
Query Neighborhood Hits	51	Target Neighborhood Hits	39	Shared Neighborhood Hits	20
SwissProt Accessions	P10639, Q52KC4, Q9D8R0	Gene names	Txn, Txn1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF).

THIO_HUMAN
NC score	0.293398 (rank : 20)	θ value	5.44631e-05 (rank : 19)
Query Neighborhood Hits	51	Target Neighborhood Hits	43	Shared Neighborhood Hits	20
SwissProt Accessions	P10599, Q96KI3	Gene names	TXN, TRDX, TRX, TRX1
Domain Architecture
Description	Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP).

TXNL2_HUMAN
NC score	0.222880 (rank : 21)	θ value	0.00134147 (rank : 22)
Query Neighborhood Hits	51	Target Neighborhood Hits	59	Shared Neighborhood Hits	21
SwissProt Accessions	O76003, Q96CE0, Q9P1B0, Q9P1B1	Gene names	TXNL2, PICOT
Domain Architecture
Description	Thioredoxin-like protein 2 (PKC-interacting cousin of thioredoxin) (PKC-theta-interacting protein) (PKCq-interacting protein).

TXNL2_MOUSE
NC score	0.197467 (rank : 22)	θ value	0.0431538 (rank : 23)
Query Neighborhood Hits	51	Target Neighborhood Hits	54	Shared Neighborhood Hits	20
SwissProt Accessions	Q9CQM9, Q9JLZ2	Gene names	Txnl2, Picot
Domain Architecture
Description	Thioredoxin-like protein 2 (PKC-interacting cousin of thioredoxin) (PKC-theta-interacting protein) (PKCq-interacting protein).

TXND8_MOUSE
NC score	0.164537 (rank : 23)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	51	Target Neighborhood Hits	41	Shared Neighborhood Hits	21
SwissProt Accessions	Q69AB2, Q78Y03, Q80YE0, Q9CQ96	Gene names	Txndc8, Sptrx3, Trx6
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6).

THIOM_HUMAN
NC score	0.157772 (rank : 24)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	22
SwissProt Accessions	Q99757, Q5JZA0, Q9UH29	Gene names	TXN2, TRX2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

TXNL1_MOUSE
NC score	0.157495 (rank : 25)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	51	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CDN6, O70379, Q3TI92	Gene names	Txnl1, Trp32, Txnl
Domain Architecture	No domain graphic available
Description	Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein).

THIOM_MOUSE
NC score	0.156964 (rank : 26)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	51	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	P97493, Q545D5	Gene names	Txn2
Domain Architecture
Description	Thioredoxin, mitochondrial precursor (Mt-Trx) (MTRX) (Thioredoxin-2).

TXNL1_HUMAN
NC score	0.154228 (rank : 27)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	51	Target Neighborhood Hits	30	Shared Neighborhood Hits	19
SwissProt Accessions	O43396	Gene names	TXNL1, TRP32, TXL, TXNL
Domain Architecture
Description	Thioredoxin-like protein 1 (32 kDa thioredoxin-related protein).

TXND2_MOUSE
NC score	0.144545 (rank : 28)	θ value	0.000786445 (rank : 21)
Query Neighborhood Hits	51	Target Neighborhood Hits	828	Shared Neighborhood Hits	23
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

PDIA3_HUMAN
NC score	0.118336 (rank : 29)	θ value	0.125558 (rank : 24)
Query Neighborhood Hits	51	Target Neighborhood Hits	57	Shared Neighborhood Hits	22
SwissProt Accessions	P30101, Q13453, Q14255, Q8IYF8, Q9UMU7	Gene names	PDIA3, ERP60, GRP58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57) (58 kDa glucose-regulated protein).

TXND8_HUMAN
NC score	0.116169 (rank : 30)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	51	Target Neighborhood Hits	27	Shared Neighborhood Hits	17
SwissProt Accessions	Q6A555, Q5T934	Gene names	TXNDC8, SPTRX3, TRX6
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 8 (Spermatid-specific thioredoxin-3) (Sptrx-3) (Thioredoxin-6).

PDIA3_MOUSE
NC score	0.115200 (rank : 31)	θ value	0.279714 (rank : 27)
Query Neighborhood Hits	51	Target Neighborhood Hits	58	Shared Neighborhood Hits	22
SwissProt Accessions	P27773	Gene names	Pdia3, Erp, Erp60, Grp58
Domain Architecture
Description	Protein disulfide-isomerase A3 precursor (EC 5.3.4.1) (Disulfide isomerase ER-60) (ERp60) (58 kDa microsomal protein) (p58) (ERp57).

TXND2_HUMAN
NC score	0.112093 (rank : 32)	θ value	0.163984 (rank : 25)
Query Neighborhood Hits	51	Target Neighborhood Hits	793	Shared Neighborhood Hits	23
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

PDIA4_HUMAN
NC score	0.104039 (rank : 33)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	51	Target Neighborhood Hits	60	Shared Neighborhood Hits	22
SwissProt Accessions	P13667	Gene names	PDIA4, ERP70, ERP72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

PDIA4_MOUSE
NC score	0.101905 (rank : 34)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	51	Target Neighborhood Hits	57	Shared Neighborhood Hits	23
SwissProt Accessions	P08003, P15841	Gene names	Pdia4, Cai, Erp72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

TXND5_MOUSE
NC score	0.095563 (rank : 35)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	51	Target Neighborhood Hits	52	Shared Neighborhood Hits	21
SwissProt Accessions	Q91W90, Q8R1I6	Gene names	Txndc5, Tlp46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46) (Plasma cell- specific thioredoxin-related protein) (PC-TRP).

TXND5_HUMAN
NC score	0.091402 (rank : 36)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	51	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q8NBS9, Q8ND33, Q8TCT2, Q9BVH9	Gene names	TXNDC5, TLP46
Domain Architecture
Description	Thioredoxin domain-containing protein 5 precursor (Thioredoxin-like protein p46) (Endoplasmic reticulum protein ERp46).

PDIA1_MOUSE
NC score	0.085686 (rank : 37)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	51	Target Neighborhood Hits	50	Shared Neighborhood Hits	20
SwissProt Accessions	P09103	Gene names	P4hb, Pdia1
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55) (Erp59).

TXD11_MOUSE
NC score	0.084248 (rank : 38)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	51	Target Neighborhood Hits	81	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K2W3, Q8BMR8, Q8VCK9	Gene names	Txndc11
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11.

PDIA1_HUMAN
NC score	0.083733 (rank : 39)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	51	Target Neighborhood Hits	56	Shared Neighborhood Hits	23
SwissProt Accessions	P07237, P30037, P32079, Q15205, Q6LDE5	Gene names	P4HB, PDI, PDIA1, PO4DB
Domain Architecture
Description	Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) (Prolyl 4- hydroxylase subunit beta) (Cellular thyroid hormone-binding protein) (p55).

TXD11_HUMAN
NC score	0.079217 (rank : 40)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	51	Target Neighborhood Hits	402	Shared Neighborhood Hits	17
SwissProt Accessions	Q6PKC3, O95887, Q6PJA6, Q8N2Q4, Q96K45, Q96K53	Gene names	TXNDC11, EFP1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 11 (EF-hand-binding protein 1).

PDIA6_MOUSE
NC score	0.067541 (rank : 41)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	51	Target Neighborhood Hits	47	Shared Neighborhood Hits	19
SwissProt Accessions	Q922R8, Q8BK54	Gene names	Pdia6, Txndc7
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 7).

PDIA5_MOUSE
NC score	0.067540 (rank : 42)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	21
SwissProt Accessions	Q921X9	Gene names	Pdia5, Pdir
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

TXND4_HUMAN
NC score	0.061854 (rank : 43)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	51	Target Neighborhood Hits	43	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BS26, O60319, Q5VWZ7, Q6UW14, Q8WX67	Gene names	TXNDC4, ERP44, KIAA0573
Domain Architecture
Description	Thioredoxin domain-containing protein 4 precursor (Endoplasmic reticulum resident protein ERp44).

PDIA6_HUMAN
NC score	0.061629 (rank : 44)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	51	Target Neighborhood Hits	46	Shared Neighborhood Hits	19
SwissProt Accessions	Q15084, Q99778	Gene names	PDIA6, TXNDC7
Domain Architecture
Description	Protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7).

PDIA2_HUMAN
NC score	0.061438 (rank : 45)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	51	Target Neighborhood Hits	49	Shared Neighborhood Hits	19
SwissProt Accessions	Q13087, Q96KJ6, Q9BW95	Gene names	PDIA2, PDIP
Domain Architecture
Description	Protein disulfide-isomerase A2 precursor (EC 5.3.4.1) (PDIp).

TXND4_MOUSE
NC score	0.060477 (rank : 46)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	51	Target Neighborhood Hits	44	Shared Neighborhood Hits	20
SwissProt Accessions	Q9D1Q6, Q3TVI1, Q6A045	Gene names	Txndc4, Erp44, Kiaa0573
Domain Architecture
Description	Thioredoxin domain-containing protein 4 precursor (Endoplasmic reticulum resident protein ERp44).

PDIA5_HUMAN
NC score	0.055605 (rank : 47)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	51	Target Neighborhood Hits	42	Shared Neighborhood Hits	18
SwissProt Accessions	Q14554	Gene names	PDIA5, PDIR
Domain Architecture
Description	Protein disulfide-isomerase A5 precursor (EC 5.3.4.1) (Protein disulfide isomerase-related protein).

TXD10_HUMAN
NC score	0.051062 (rank : 48)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	51	Target Neighborhood Hits	47	Shared Neighborhood Hits	18
SwissProt Accessions	Q96JJ7, Q8N5J0, Q9NWJ9	Gene names	TXNDC10, KIAA1830, TMX3
Domain Architecture	No domain graphic available
Description	Protein disulfide-isomerase TXNDC10 precursor (EC 5.3.4.1) (Thioredoxin domain-containing protein 10) (Thioredoxin-related transmembrane protein 3).

DPY30_MOUSE
NC score	0.050626 (rank : 49)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	51	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q99LT0	Gene names
Domain Architecture
Description	Dpy-30-like protein.

DPY30_HUMAN
NC score	0.050572 (rank : 50)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	51	Target Neighborhood Hits	9	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C005	Gene names
Domain Architecture
Description	Dpy-30-like protein.

CEP35_HUMAN
NC score	0.047754 (rank : 51)	θ value	0.21417 (rank : 26)
Query Neighborhood Hits	51	Target Neighborhood Hits	811	Shared Neighborhood Hits	9
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

FEZ1_MOUSE
NC score	0.024993 (rank : 52)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	51	Target Neighborhood Hits	93	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K0X8	Gene names	Fez1
Domain Architecture	No domain graphic available
Description	Fasciculation and elongation protein zeta 1 (Zygin-1) (Zygin I).

GHR_MOUSE
NC score	0.023825 (rank : 53)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	51	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	P16882, P16590, Q61653, Q6DI66, Q80W86, Q8R1M5, Q920Z3, Q9R264	Gene names	Ghr
Domain Architecture
Description	Growth hormone receptor precursor (GH receptor) (Somatotropin receptor) [Contains: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)].

TGON2_MOUSE
NC score	0.022005 (rank : 54)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	51	Target Neighborhood Hits	277	Shared Neighborhood Hits	5
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

BICD1_HUMAN
NC score	0.011550 (rank : 55)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	51	Target Neighborhood Hits	844	Shared Neighborhood Hits	7
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BICD1_MOUSE
NC score	0.010418 (rank : 56)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	51	Target Neighborhood Hits	837	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

PDE6C_HUMAN
NC score	0.010229 (rank : 57)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	51	Target Neighborhood Hits	56	Shared Neighborhood Hits	3
SwissProt Accessions	P51160, Q5VY29	Gene names	PDE6C, PDEA2
Domain Architecture
Description	Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).

PDE6C_MOUSE
NC score	0.008659 (rank : 58)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	51	Target Neighborhood Hits	45	Shared Neighborhood Hits	4
SwissProt Accessions	Q91ZQ1, Q8R0D4	Gene names	Pde6c
Domain Architecture	No domain graphic available
Description	Cone cGMP-specific 3',5'-cyclic phosphodiesterase alpha'-subunit (EC 3.1.4.35) (cGMP phosphodiesterase 6C).

GABP2_HUMAN
NC score	0.008426 (rank : 59)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	51	Target Neighborhood Hits	454	Shared Neighborhood Hits	4
SwissProt Accessions	Q06547, Q06545, Q12940, Q12941, Q12942, Q8IYD0	Gene names	GABPB2, E4TF1B, GABPB, GABPB1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1) (Transcription factor E4TF1-53) (Transcription factor E4TF1-47) (Nuclear respiratory factor 2).

AR13B_MOUSE
NC score	0.008305 (rank : 60)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	51	Target Neighborhood Hits	245	Shared Neighborhood Hits	2
SwissProt Accessions	Q640N2	Gene names	Arl13b, Arl2l1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-like protein 13B (ADP-ribosylation factor-like protein 2-like 1) (ARL2-like protein 1).

GABP2_MOUSE
NC score	0.007912 (rank : 61)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	51	Target Neighborhood Hits	429	Shared Neighborhood Hits	4
SwissProt Accessions	Q00420, Q00421, Q8BS31, Q91YZ0, Q9QVV2	Gene names	Gabpb2, Gabpb, Gabpb1
Domain Architecture
Description	GA-binding protein beta chain (GABP subunit beta-2) (GABP-2) (GABP subunit beta-1) (GABPB-1).

PADI4_MOUSE
NC score	0.007347 (rank : 62)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	51	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z183, Q75WC7	Gene names	Padi4, Pdi4
Domain Architecture
Description	Protein-arginine deiminase type-4 (EC 3.5.3.15) (Protein-arginine deiminase type IV) (Peptidylarginine deiminase IV).

DIAP3_HUMAN
NC score	0.005527 (rank : 63)	θ value	8.99809 (rank : 49)
Query Neighborhood Hits	51	Target Neighborhood Hits	209	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

TITIN_HUMAN
NC score	0.002288 (rank : 64)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	51	Target Neighborhood Hits	2923	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).