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Network neighborhood for query Sequence : TRPM2_HUMAN

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TRPM2_HUMAN
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TRPM2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	64	Target Neighborhood Hits	64	Shared Neighborhood Hits	64
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

TRPM2_MOUSE
θ value	0 (rank : 2)	NC score	0.996452 (rank : 2)
Query Neighborhood Hits	64	Target Neighborhood Hits	61	Shared Neighborhood Hits	41
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

TRPM8_HUMAN
θ value	0 (rank : 3)	NC score	0.938026 (rank : 3)
Query Neighborhood Hits	64	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

TRPM8_MOUSE
θ value	0 (rank : 4)	NC score	0.937109 (rank : 4)
Query Neighborhood Hits	64	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

TRPM7_HUMAN
θ value	3.27947e-143 (rank : 5)	NC score	0.858745 (rank : 6)
Query Neighborhood Hits	64	Target Neighborhood Hits	104	Shared Neighborhood Hits	33
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

TRPM3_HUMAN
θ value	9.035e-101 (rank : 6)	NC score	0.862323 (rank : 5)
Query Neighborhood Hits	64	Target Neighborhood Hits	121	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

TRPM7_MOUSE
θ value	1.10445e-98 (rank : 7)	NC score	0.845341 (rank : 8)
Query Neighborhood Hits	64	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

TRPM6_MOUSE
θ value	1.44581e-90 (rank : 8)	NC score	0.847341 (rank : 7)
Query Neighborhood Hits	64	Target Neighborhood Hits	78	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM6_HUMAN
θ value	7.42547e-87 (rank : 9)	NC score	0.841428 (rank : 9)
Query Neighborhood Hits	64	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

NUDT9_MOUSE
θ value	2.26708e-35 (rank : 10)	NC score	0.472803 (rank : 14)
Query Neighborhood Hits	64	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BVU5, Q3TZ68, Q8K1J4	Gene names	Nudt9
Domain Architecture	No domain graphic available
Description	ADP-ribose pyrophosphatase, mitochondrial precursor (EC 3.6.1.13) (ADP-ribose diphosphatase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) (Nucleoside diphosphate- linked moiety X motif 9) (Nudix motif 9).

NUDT9_HUMAN
θ value	1.9192e-34 (rank : 11)	NC score	0.471962 (rank : 15)
Query Neighborhood Hits	64	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BW91, Q8NBN1, Q8NCB9, Q8NG25	Gene names	NUDT9, NUDT10
Domain Architecture
Description	ADP-ribose pyrophosphatase, mitochondrial precursor (EC 3.6.1.13) (ADP-ribose diphosphatase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) (Nucleoside diphosphate- linked moiety X motif 9) (Nudix motif 9).

TRPC5_HUMAN
θ value	2.88119e-14 (rank : 12)	NC score	0.492399 (rank : 13)
Query Neighborhood Hits	64	Target Neighborhood Hits	122	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

TRPC5_MOUSE
θ value	2.88119e-14 (rank : 13)	NC score	0.492460 (rank : 12)
Query Neighborhood Hits	64	Target Neighborhood Hits	124	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC3_HUMAN
θ value	4.91457e-14 (rank : 14)	NC score	0.423160 (rank : 18)
Query Neighborhood Hits	64	Target Neighborhood Hits	137	Shared Neighborhood Hits	34
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

TRPC4_HUMAN
θ value	4.91457e-14 (rank : 15)	NC score	0.503932 (rank : 10)
Query Neighborhood Hits	64	Target Neighborhood Hits	140	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
θ value	6.41864e-14 (rank : 16)	NC score	0.502609 (rank : 11)
Query Neighborhood Hits	64	Target Neighborhood Hits	141	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC3_MOUSE
θ value	3.18553e-13 (rank : 17)	NC score	0.428018 (rank : 17)
Query Neighborhood Hits	64	Target Neighborhood Hits	131	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

NUD9P_HUMAN
θ value	1.33837e-11 (rank : 18)	NC score	0.408060 (rank : 19)
Query Neighborhood Hits	64	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N2Z3	Gene names	NUDT9P1, C10orf98
Domain Architecture	No domain graphic available
Description	Putative nucleoside diphosphate-linked moiety X motif 9P1.

TRPC1_HUMAN
θ value	6.21693e-09 (rank : 19)	NC score	0.394132 (rank : 21)
Query Neighborhood Hits	64	Target Neighborhood Hits	91	Shared Neighborhood Hits	32
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC1_MOUSE
θ value	6.21693e-09 (rank : 20)	NC score	0.394487 (rank : 20)
Query Neighborhood Hits	64	Target Neighborhood Hits	87	Shared Neighborhood Hits	32
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPV3_HUMAN
θ value	6.43352e-06 (rank : 21)	NC score	0.269122 (rank : 26)
Query Neighborhood Hits	64	Target Neighborhood Hits	198	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPC6_MOUSE
θ value	1.87187e-05 (rank : 22)	NC score	0.384573 (rank : 22)
Query Neighborhood Hits	64	Target Neighborhood Hits	171	Shared Neighborhood Hits	35
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPV3_MOUSE
θ value	2.44474e-05 (rank : 23)	NC score	0.264683 (rank : 27)
Query Neighborhood Hits	64	Target Neighborhood Hits	188	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV4_HUMAN
θ value	3.19293e-05 (rank : 24)	NC score	0.210217 (rank : 28)
Query Neighborhood Hits	64	Target Neighborhood Hits	150	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPC6_HUMAN
θ value	5.44631e-05 (rank : 25)	NC score	0.382065 (rank : 23)
Query Neighborhood Hits	64	Target Neighborhood Hits	171	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPC7_HUMAN
θ value	0.000270298 (rank : 26)	NC score	0.374968 (rank : 25)
Query Neighborhood Hits	64	Target Neighborhood Hits	123	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPC7_MOUSE
θ value	0.000270298 (rank : 27)	NC score	0.375934 (rank : 24)
Query Neighborhood Hits	64	Target Neighborhood Hits	114	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC2_MOUSE
θ value	0.000461057 (rank : 28)	NC score	0.438888 (rank : 16)
Query Neighborhood Hits	64	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

TRPV4_MOUSE
θ value	0.000786445 (rank : 29)	NC score	0.190275 (rank : 31)
Query Neighborhood Hits	64	Target Neighborhood Hits	117	Shared Neighborhood Hits	32
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV1_HUMAN
θ value	0.00102713 (rank : 30)	NC score	0.208889 (rank : 29)
Query Neighborhood Hits	64	Target Neighborhood Hits	184	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV1_MOUSE
θ value	0.00102713 (rank : 31)	NC score	0.204112 (rank : 30)
Query Neighborhood Hits	64	Target Neighborhood Hits	189	Shared Neighborhood Hits	34
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV6_HUMAN
θ value	0.0961366 (rank : 32)	NC score	0.176260 (rank : 32)
Query Neighborhood Hits	64	Target Neighborhood Hits	262	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TRPV6_MOUSE
θ value	0.163984 (rank : 33)	NC score	0.160690 (rank : 33)
Query Neighborhood Hits	64	Target Neighborhood Hits	284	Shared Neighborhood Hits	35
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

TRPV5_HUMAN
θ value	0.62314 (rank : 34)	NC score	0.151262 (rank : 34)
Query Neighborhood Hits	64	Target Neighborhood Hits	261	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

OSBL1_MOUSE
θ value	0.813845 (rank : 35)	NC score	0.010980 (rank : 49)
Query Neighborhood Hits	64	Target Neighborhood Hits	336	Shared Neighborhood Hits	13
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

CCD42_MOUSE
θ value	1.06291 (rank : 36)	NC score	0.027785 (rank : 43)
Query Neighborhood Hits	64	Target Neighborhood Hits	284	Shared Neighborhood Hits	10
SwissProt Accessions	Q5SV66, Q8BNY1	Gene names	Ccdc42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

MYH3_HUMAN
θ value	1.38821 (rank : 37)	NC score	0.004967 (rank : 62)
Query Neighborhood Hits	64	Target Neighborhood Hits	1660	Shared Neighborhood Hits	15
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

SCN7A_HUMAN
θ value	1.38821 (rank : 38)	NC score	0.016592 (rank : 45)
Query Neighborhood Hits	64	Target Neighborhood Hits	135	Shared Neighborhood Hits	10
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

CAC1G_HUMAN
θ value	1.81305 (rank : 39)	NC score	0.015725 (rank : 47)
Query Neighborhood Hits	64	Target Neighborhood Hits	587	Shared Neighborhood Hits	6
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

KIF2A_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.008806 (rank : 55)
Query Neighborhood Hits	64	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	O00139, Q8N5Q7	Gene names	KIF2A, KIF2, KNS2
Domain Architecture
Description	Kinesin-like protein KIF2A (Kinesin-2) (HK2).

KIF2A_MOUSE
θ value	1.81305 (rank : 41)	NC score	0.008935 (rank : 54)
Query Neighborhood Hits	64	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	P28740	Gene names	Kif2a, Kif2, Kns2
Domain Architecture
Description	Kinesin-like protein KIF2A.

MYH13_HUMAN
θ value	1.81305 (rank : 42)	NC score	0.004817 (rank : 65)
Query Neighborhood Hits	64	Target Neighborhood Hits	1504	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

CAC1I_HUMAN
θ value	2.36792 (rank : 43)	NC score	0.015917 (rank : 46)
Query Neighborhood Hits	64	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

MYST3_MOUSE
θ value	2.36792 (rank : 44)	NC score	0.005962 (rank : 61)
Query Neighborhood Hits	64	Target Neighborhood Hits	688	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

CASP_MOUSE
θ value	3.0926 (rank : 45)	NC score	0.009242 (rank : 53)
Query Neighborhood Hits	64	Target Neighborhood Hits	1152	Shared Neighborhood Hits	14
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CUTL1_MOUSE
θ value	3.0926 (rank : 46)	NC score	0.009267 (rank : 52)
Query Neighborhood Hits	64	Target Neighborhood Hits	1620	Shared Neighborhood Hits	15
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

TRPA1_MOUSE
θ value	3.0926 (rank : 47)	NC score	0.027130 (rank : 44)
Query Neighborhood Hits	64	Target Neighborhood Hits	343	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

TRPV5_MOUSE
θ value	3.0926 (rank : 48)	NC score	0.146521 (rank : 35)
Query Neighborhood Hits	64	Target Neighborhood Hits	278	Shared Neighborhood Hits	34
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

ANKR7_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.013684 (rank : 48)
Query Neighborhood Hits	64	Target Neighborhood Hits	286	Shared Neighborhood Hits	16
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

APC_MOUSE
θ value	4.03905 (rank : 50)	NC score	0.010770 (rank : 50)
Query Neighborhood Hits	64	Target Neighborhood Hits	441	Shared Neighborhood Hits	9
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

DAZP1_MOUSE
θ value	4.03905 (rank : 51)	NC score	0.004899 (rank : 64)
Query Neighborhood Hits	64	Target Neighborhood Hits	313	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JII5	Gene names	Dazap1
Domain Architecture
Description	DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1).

STK31_HUMAN
θ value	4.03905 (rank : 52)	NC score	0.010067 (rank : 51)
Query Neighborhood Hits	64	Target Neighborhood Hits	570	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

CASP_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.007676 (rank : 56)
Query Neighborhood Hits	64	Target Neighborhood Hits	1131	Shared Neighborhood Hits	13
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CUTL1_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.006944 (rank : 58)
Query Neighborhood Hits	64	Target Neighborhood Hits	1574	Shared Neighborhood Hits	13
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

DG2L6_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.006533 (rank : 60)
Query Neighborhood Hits	64	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZPD8, Q6IEE2	Gene names	DGAT2L6, DC3
Domain Architecture	No domain graphic available
Description	Diacylglycerol O-acyltransferase 2-like protein 6 (EC 2.3.1.-) (Diacylglycerol O-acyltransferase candidate 3) (hDC3).

ITA5_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.004064 (rank : 66)
Query Neighborhood Hits	64	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	P08648, Q96HA5	Gene names	ITGA5, FNRA
Domain Architecture
Description	Integrin alpha-5 precursor (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD49e antigen) [Contains: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain].

TNK1_HUMAN
θ value	5.27518 (rank : 57)	NC score	-0.002042 (rank : 71)
Query Neighborhood Hits	64	Target Neighborhood Hits	815	Shared Neighborhood Hits	2
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).

BASP_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.006817 (rank : 59)
Query Neighborhood Hits	64	Target Neighborhood Hits	321	Shared Neighborhood Hits	4
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

AT11A_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.002262 (rank : 69)
Query Neighborhood Hits	64	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	P98197	Gene names	Atp11a
Domain Architecture
Description	Probable phospholipid-transporting ATPase IH (EC 3.6.3.1) (ATPase class I type 11A) (ATPase IS).

DAZP1_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.003497 (rank : 67)
Query Neighborhood Hits	64	Target Neighborhood Hits	313	Shared Neighborhood Hits	3
SwissProt Accessions	Q96EP5, Q96MJ3, Q9NRR9	Gene names	DAZAP1
Domain Architecture
Description	DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1).

GCC2_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.002382 (rank : 68)
Query Neighborhood Hits	64	Target Neighborhood Hits	1619	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

REST_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.001498 (rank : 70)
Query Neighborhood Hits	64	Target Neighborhood Hits	1506	Shared Neighborhood Hits	14
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

TBC14_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.004910 (rank : 63)
Query Neighborhood Hits	64	Target Neighborhood Hits	124	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2M4, Q8IW15	Gene names	TBC1D14, KIAA1322
Domain Architecture
Description	TBC1 domain family member 14.

WRIP1_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.006960 (rank : 57)
Query Neighborhood Hits	64	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

EF2K_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.140357 (rank : 38)
Query Neighborhood Hits	64	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	O00418	Gene names	EEF2K
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

EF2K_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.145858 (rank : 37)
Query Neighborhood Hits	64	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	O08796	Gene names	Eef2k
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

PK2L1_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.093189 (rank : 40)
Query Neighborhood Hits	64	Target Neighborhood Hits	132	Shared Neighborhood Hits	30
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PK2L2_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.056724 (rank : 42)
Query Neighborhood Hits	64	Target Neighborhood Hits	90	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L2_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.064205 (rank : 41)
Query Neighborhood Hits	64	Target Neighborhood Hits	84	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

TRPV2_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.130014 (rank : 39)
Query Neighborhood Hits	64	Target Neighborhood Hits	130	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

TRPV2_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.146366 (rank : 36)
Query Neighborhood Hits	64	Target Neighborhood Hits	111	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

Hits sorted by NC score

TRPM2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	64	Target Neighborhood Hits	64	Shared Neighborhood Hits	64
SwissProt Accessions	O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93	Gene names	TRPM2, EREG1, KNP3, LTRPC2, TRPC7
Domain Architecture
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7) (Estrogen- responsive element-associated gene 1 protein).

TRPM2_MOUSE
NC score	0.996452 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	64	Target Neighborhood Hits	61	Shared Neighborhood Hits	41
SwissProt Accessions	Q91YD4	Gene names	Trpm2, Ltrpc2, Trpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 2 (EC 3.6.1.13) (Long transient receptor potential channel 2) (LTrpC2) (LTrpC-2) (Transient receptor potential channel 7) (TrpC7).

TRPM8_HUMAN
NC score	0.938026 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	64	Target Neighborhood Hits	65	Shared Neighborhood Hits	33
SwissProt Accessions	Q7Z2W7, Q6QNH9, Q8TAC3, Q8TDX8, Q9BVK1	Gene names	TRPM8, LTRPC6, TRPP8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8 (Transient receptor potential-p8) (Trp-p8) (Long transient receptor potential channel 6) (LTrpC6).

TRPM8_MOUSE
NC score	0.937109 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	64	Target Neighborhood Hits	58	Shared Neighborhood Hits	31
SwissProt Accessions	Q8R4D5	Gene names	Trpm8, Trpp8
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 8.

TRPM3_HUMAN
NC score	0.862323 (rank : 5)	θ value	9.035e-101 (rank : 6)
Query Neighborhood Hits	64	Target Neighborhood Hits	121	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HCF6, Q5VW02, Q5VW03, Q5VW04, Q5W5T7, Q86SH0, Q86SH6, Q86UL0, Q86WK1, Q86WK2, Q86WK3, Q86WK4, Q86YZ9, Q86Z00, Q86Z01	Gene names	TRPM3, KIAA1616, LTRPC3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC3) (Melastatin-2) (MLSN2).

TRPM7_HUMAN
NC score	0.858745 (rank : 6)	θ value	3.27947e-143 (rank : 5)
Query Neighborhood Hits	64	Target Neighborhood Hits	104	Shared Neighborhood Hits	33
SwissProt Accessions	Q96QT4, Q6ZMF5, Q86VJ4, Q8NBW2, Q9BXB2, Q9NXQ2	Gene names	TRPM7, CHAK1, LTRPC7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1).

TRPM6_MOUSE
NC score	0.847341 (rank : 7)	θ value	1.44581e-90 (rank : 8)
Query Neighborhood Hits	64	Target Neighborhood Hits	78	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CIR4	Gene names	Trpm6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPM7_MOUSE
NC score	0.845341 (rank : 8)	θ value	1.10445e-98 (rank : 7)
Query Neighborhood Hits	64	Target Neighborhood Hits	113	Shared Neighborhood Hits	32
SwissProt Accessions	Q923J1, Q8C7S7, Q8CE54, Q921Y5, Q925B2, Q9CUT2, Q9JLQ1	Gene names	Trpm7, Chak, Ltrpc7
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 7 (EC 2.7.11.1) (Long transient receptor potential channel 7) (LTrpC7) (Channel-kinase 1) (Transient receptor potential-phospholipase C- interacting kinase) (TRP-PLIK).

TRPM6_HUMAN
NC score	0.841428 (rank : 9)	θ value	7.42547e-87 (rank : 9)
Query Neighborhood Hits	64	Target Neighborhood Hits	91	Shared Neighborhood Hits	33
SwissProt Accessions	Q9BX84, Q6VPR8, Q6VPR9, Q6VPS0, Q6VPS1, Q6VPS2	Gene names	TRPM6, CHAK2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily M member 6 (EC 2.7.11.1) (Channel kinase 2) (Melastatin-related TRP cation channel 6).

TRPC4_HUMAN
NC score	0.503932 (rank : 10)	θ value	4.91457e-14 (rank : 15)
Query Neighborhood Hits	64	Target Neighborhood Hits	140	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UBN4, Q15721, Q9UIB0, Q9UIB1, Q9UIB2	Gene names	TRPC4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (trp-related protein 4) (hTrp-4) (hTrp4).

TRPC4_MOUSE
NC score	0.502609 (rank : 11)	θ value	6.41864e-14 (rank : 16)
Query Neighborhood Hits	64	Target Neighborhood Hits	141	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QUQ5, Q62350, Q9QUQ9, Q9QZC0	Gene names	Trpc4, Trrp4
Domain Architecture
Description	Short transient receptor potential channel 4 (TrpC4) (Receptor- activated cation channel TRP4) (Capacitative calcium entry channel Trp4).

TRPC5_MOUSE
NC score	0.492460 (rank : 12)	θ value	2.88119e-14 (rank : 13)
Query Neighborhood Hits	64	Target Neighborhood Hits	124	Shared Neighborhood Hits	33
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

TRPC5_HUMAN
NC score	0.492399 (rank : 13)	θ value	2.88119e-14 (rank : 12)
Query Neighborhood Hits	64	Target Neighborhood Hits	122	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UL62, O75233, Q5JXY8, Q9Y514	Gene names	TRPC5, TRP5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Htrp-5) (Htrp5).

NUDT9_MOUSE
NC score	0.472803 (rank : 14)	θ value	2.26708e-35 (rank : 10)
Query Neighborhood Hits	64	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BVU5, Q3TZ68, Q8K1J4	Gene names	Nudt9
Domain Architecture	No domain graphic available
Description	ADP-ribose pyrophosphatase, mitochondrial precursor (EC 3.6.1.13) (ADP-ribose diphosphatase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) (Nucleoside diphosphate- linked moiety X motif 9) (Nudix motif 9).

NUDT9_HUMAN
NC score	0.471962 (rank : 15)	θ value	1.9192e-34 (rank : 11)
Query Neighborhood Hits	64	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BW91, Q8NBN1, Q8NCB9, Q8NG25	Gene names	NUDT9, NUDT10
Domain Architecture
Description	ADP-ribose pyrophosphatase, mitochondrial precursor (EC 3.6.1.13) (ADP-ribose diphosphatase) (Adenosine diphosphoribose pyrophosphatase) (ADPR-PPase) (ADP-ribose phosphohydrolase) (Nucleoside diphosphate- linked moiety X motif 9) (Nudix motif 9).

TRPC2_MOUSE
NC score	0.438888 (rank : 16)	θ value	0.000461057 (rank : 28)
Query Neighborhood Hits	64	Target Neighborhood Hits	84	Shared Neighborhood Hits	32
SwissProt Accessions	Q9R244, Q9ES59, Q9ES60, Q9R243	Gene names	Trpc2, Trp2, Trrp2
Domain Architecture
Description	Short transient receptor potential channel 2 (TrpC2) (mTrp2).

TRPC3_MOUSE
NC score	0.428018 (rank : 17)	θ value	3.18553e-13 (rank : 17)
Query Neighborhood Hits	64	Target Neighborhood Hits	131	Shared Neighborhood Hits	34
SwissProt Accessions	Q9QZC1, Q61058	Gene names	Trpc3, Trp3, Trrp3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Transient receptor protein 3) (Mtrp3) (Receptor-activated cation channel TRP3) (trp-related protein 3).

TRPC3_HUMAN
NC score	0.423160 (rank : 18)	θ value	4.91457e-14 (rank : 14)
Query Neighborhood Hits	64	Target Neighborhood Hits	137	Shared Neighborhood Hits	34
SwissProt Accessions	Q13507, O00593, Q15660	Gene names	TRPC3, TRP3
Domain Architecture
Description	Short transient receptor potential channel 3 (TrpC3) (Htrp-3) (Htrp3).

NUD9P_HUMAN
NC score	0.408060 (rank : 19)	θ value	1.33837e-11 (rank : 18)
Query Neighborhood Hits	64	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q8N2Z3	Gene names	NUDT9P1, C10orf98
Domain Architecture	No domain graphic available
Description	Putative nucleoside diphosphate-linked moiety X motif 9P1.

TRPC1_MOUSE
NC score	0.394487 (rank : 20)	θ value	6.21693e-09 (rank : 20)
Query Neighborhood Hits	64	Target Neighborhood Hits	87	Shared Neighborhood Hits	32
SwissProt Accessions	Q61056, O35722	Gene names	Trpc1, Trp1, Trrp1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (Mtrp1) (Trp-related protein 1).

TRPC1_HUMAN
NC score	0.394132 (rank : 21)	θ value	6.21693e-09 (rank : 19)
Query Neighborhood Hits	64	Target Neighborhood Hits	91	Shared Neighborhood Hits	32
SwissProt Accessions	P48995	Gene names	TRPC1, TRP1
Domain Architecture
Description	Short transient receptor potential channel 1 (TrpC1) (TRP-1 protein).

TRPC6_MOUSE
NC score	0.384573 (rank : 22)	θ value	1.87187e-05 (rank : 22)
Query Neighborhood Hits	64	Target Neighborhood Hits	171	Shared Neighborhood Hits	35
SwissProt Accessions	Q61143, Q9Z2J1	Gene names	Trpc6, Trp6, Trrp6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6) (Calcium entry channel).

TRPC6_HUMAN
NC score	0.382065 (rank : 23)	θ value	5.44631e-05 (rank : 25)
Query Neighborhood Hits	64	Target Neighborhood Hits	171	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y210, Q9HCW3, Q9NQA8, Q9NQA9	Gene names	TRPC6, TRP6
Domain Architecture
Description	Short transient receptor potential channel 6 (TrpC6).

TRPC7_MOUSE
NC score	0.375934 (rank : 24)	θ value	0.000270298 (rank : 27)
Query Neighborhood Hits	64	Target Neighborhood Hits	114	Shared Neighborhood Hits	34
SwissProt Accessions	Q9WVC5	Gene names	Trpc7, Trp7, Trrp8
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (mTRP7).

TRPC7_HUMAN
NC score	0.374968 (rank : 25)	θ value	0.000270298 (rank : 26)
Query Neighborhood Hits	64	Target Neighborhood Hits	123	Shared Neighborhood Hits	37
SwissProt Accessions	Q9HCX4	Gene names	TRPC7, TRP7
Domain Architecture
Description	Short transient receptor potential channel 7 (TrpC7) (TRP7 protein).

TRPV3_HUMAN
NC score	0.269122 (rank : 26)	θ value	6.43352e-06 (rank : 21)
Query Neighborhood Hits	64	Target Neighborhood Hits	198	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NET8, Q8NDW7, Q8NET9, Q8NFH2	Gene names	TRPV3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3) (Vanilloid receptor-like 3) (VRL-3).

TRPV3_MOUSE
NC score	0.264683 (rank : 27)	θ value	2.44474e-05 (rank : 23)
Query Neighborhood Hits	64	Target Neighborhood Hits	188	Shared Neighborhood Hits	35
SwissProt Accessions	Q8K424, Q5SV08	Gene names	Trpv3
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 3 (TrpV3).

TRPV4_HUMAN
NC score	0.210217 (rank : 28)	θ value	3.19293e-05 (rank : 24)
Query Neighborhood Hits	64	Target Neighborhood Hits	150	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HBA0, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBC0	Gene names	TRPV4, VRL2, VROAC
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (VRL-2) (Vanilloid receptor-related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV1_HUMAN
NC score	0.208889 (rank : 29)	θ value	0.00102713 (rank : 30)
Query Neighborhood Hits	64	Target Neighborhood Hits	184	Shared Neighborhood Hits	34
SwissProt Accessions	Q8NER1, Q9H0G9, Q9H303, Q9H304, Q9NQ74, Q9NY22	Gene names	TRPV1, VR1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Capsaicin receptor).

TRPV1_MOUSE
NC score	0.204112 (rank : 30)	θ value	0.00102713 (rank : 31)
Query Neighborhood Hits	64	Target Neighborhood Hits	189	Shared Neighborhood Hits	34
SwissProt Accessions	Q704Y3, Q5SSE1, Q5SSE2, Q5SSE4, Q5WPV5, Q68SW0	Gene names	Trpv1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 1 (TrpV1) (osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1).

TRPV4_MOUSE
NC score	0.190275 (rank : 31)	θ value	0.000786445 (rank : 29)
Query Neighborhood Hits	64	Target Neighborhood Hits	117	Shared Neighborhood Hits	32
SwissProt Accessions	Q9EPK8, Q91XR5, Q9EQZ4, Q9ERZ7, Q9ES76	Gene names	Trpv4, Trp12, Vrl2, Vroac
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 4 (TrpV4) (osm-9-like TRP channel 4) (OTRPC4) (Vanilloid receptor-like channel 2) (Vanilloid receptor-like protein 2) (Vanilloid receptor- related osmotically-activated channel) (VR-OAC) (Transient receptor potential protein 12) (TRP12).

TRPV6_HUMAN
NC score	0.176260 (rank : 32)	θ value	0.0961366 (rank : 32)
Query Neighborhood Hits	64	Target Neighborhood Hits	262	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H1D0, Q8TDL3, Q8WXR8, Q96LC5, Q9H1D1, Q9H296	Gene names	TRPV6, ECAC2
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1) (CaT-like) (CaT-L).

TRPV6_MOUSE
NC score	0.160690 (rank : 33)	θ value	0.163984 (rank : 33)
Query Neighborhood Hits	64	Target Neighborhood Hits	284	Shared Neighborhood Hits	35
SwissProt Accessions	Q91WD2	Gene names	Trpv6
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 6 (TrpV6) (Epithelial calcium channel 2) (ECaC2) (Calcium transport protein 1) (CaT1).

TRPV5_HUMAN
NC score	0.151262 (rank : 34)	θ value	0.62314 (rank : 34)
Query Neighborhood Hits	64	Target Neighborhood Hits	261	Shared Neighborhood Hits	34
SwissProt Accessions	Q9NQA5, Q8NDW5, Q8NDX7, Q8NDX8, Q96PM6	Gene names	TRPV5, ECAC1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV5_MOUSE
NC score	0.146521 (rank : 35)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	64	Target Neighborhood Hits	278	Shared Neighborhood Hits	34
SwissProt Accessions	P69744	Gene names	Trpv5
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 5 (TrpV5) (osm-9-like TRP channel 3) (OTRPC3) (Epithelial calcium channel 1) (ECaC1) (Calcium transport protein 2) (CaT2).

TRPV2_MOUSE
NC score	0.146366 (rank : 36)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	64	Target Neighborhood Hits	111	Shared Neighborhood Hits	22
SwissProt Accessions	Q9WTR1, Q99K71	Gene names	Trpv2, Grc
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Growth factor-regulated calcium channel) (GRC).

EF2K_MOUSE
NC score	0.145858 (rank : 37)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	64	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	O08796	Gene names	Eef2k
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

EF2K_HUMAN
NC score	0.140357 (rank : 38)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	64	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	O00418	Gene names	EEF2K
Domain Architecture
Description	Elongation factor 2 kinase (EC 2.7.11.20) (eEF-2 kinase) (eEF-2K) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase).

TRPV2_HUMAN
NC score	0.130014 (rank : 39)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	64	Target Neighborhood Hits	130	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y5S1, Q9Y670	Gene names	TRPV2, VRL
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily V member 2 (TrpV2) (osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1).

PK2L1_HUMAN
NC score	0.093189 (rank : 40)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	64	Target Neighborhood Hits	132	Shared Neighborhood Hits	30
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

PK2L2_MOUSE
NC score	0.064205 (rank : 41)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	64	Target Neighborhood Hits	84	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JLG4	Gene names	Pkd2l2
Domain Architecture
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

PK2L2_HUMAN
NC score	0.056724 (rank : 42)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	64	Target Neighborhood Hits	90	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZM6, Q9UNJ0	Gene names	PKD2L2
Domain Architecture	No domain graphic available
Description	Polycystic kidney disease 2-like 2 protein (Polycystin-L2).

CCD42_MOUSE
NC score	0.027785 (rank : 43)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	64	Target Neighborhood Hits	284	Shared Neighborhood Hits	10
SwissProt Accessions	Q5SV66, Q8BNY1	Gene names	Ccdc42
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 42.

TRPA1_MOUSE
NC score	0.027130 (rank : 44)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	64	Target Neighborhood Hits	343	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

SCN7A_HUMAN
NC score	0.016592 (rank : 45)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	64	Target Neighborhood Hits	135	Shared Neighborhood Hits	10
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

CAC1I_HUMAN
NC score	0.015917 (rank : 46)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	64	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	Q9P0X4, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6	Gene names	CACNA1I, KIAA1120
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage- gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3).

CAC1G_HUMAN
NC score	0.015725 (rank : 47)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	64	Target Neighborhood Hits	587	Shared Neighborhood Hits	6
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

ANKR7_HUMAN
NC score	0.013684 (rank : 48)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	64	Target Neighborhood Hits	286	Shared Neighborhood Hits	16
SwissProt Accessions	Q92527, Q96QN1, Q9UDM3	Gene names	ANKRD7
Domain Architecture
Description	Ankyrin repeat domain-containing protein 7 (Testis-specific protein TSA806).

OSBL1_MOUSE
NC score	0.010980 (rank : 49)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	64	Target Neighborhood Hits	336	Shared Neighborhood Hits	13
SwissProt Accessions	Q91XL9, O88318, Q3TH97, Q673L8, Q6DFU6	Gene names	Osbpl1a, Orp1, Orp1a
Domain Architecture
Description	Oxysterol-binding protein-related protein 1 (OSBP-related protein 1) (ORP-1).

APC_MOUSE
NC score	0.010770 (rank : 50)	θ value	4.03905 (rank : 50)
Query Neighborhood Hits	64	Target Neighborhood Hits	441	Shared Neighborhood Hits	9
SwissProt Accessions	Q61315, Q62044	Gene names	Apc
Domain Architecture
Description	Adenomatous polyposis coli protein (Protein APC) (mAPC).

STK31_HUMAN
NC score	0.010067 (rank : 51)	θ value	4.03905 (rank : 52)
Query Neighborhood Hits	64	Target Neighborhood Hits	570	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BXU1, Q9BXH8	Gene names	STK31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1) (Serine/threonine- protein kinase NYD-SPK).

CUTL1_MOUSE
NC score	0.009267 (rank : 52)	θ value	3.0926 (rank : 46)
Query Neighborhood Hits	64	Target Neighborhood Hits	1620	Shared Neighborhood Hits	15
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

CASP_MOUSE
NC score	0.009242 (rank : 53)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	64	Target Neighborhood Hits	1152	Shared Neighborhood Hits	14
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

KIF2A_MOUSE
NC score	0.008935 (rank : 54)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	64	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	P28740	Gene names	Kif2a, Kif2, Kns2
Domain Architecture
Description	Kinesin-like protein KIF2A.

KIF2A_HUMAN
NC score	0.008806 (rank : 55)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	64	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	O00139, Q8N5Q7	Gene names	KIF2A, KIF2, KNS2
Domain Architecture
Description	Kinesin-like protein KIF2A (Kinesin-2) (HK2).

CASP_HUMAN
NC score	0.007676 (rank : 56)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	64	Target Neighborhood Hits	1131	Shared Neighborhood Hits	13
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

WRIP1_HUMAN
NC score	0.006960 (rank : 57)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	64	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	Q96S55, Q53EP6, Q59ET8, Q5W0E2, Q5W0E4, Q8WV26, Q9H681, Q9NRJ6	Gene names	WRNIP1, WHIP
Domain Architecture	No domain graphic available
Description	ATPase WRNIP1 (Werner helicase-interacting protein 1).

CUTL1_HUMAN
NC score	0.006944 (rank : 58)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	64	Target Neighborhood Hits	1574	Shared Neighborhood Hits	13
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

BASP_HUMAN
NC score	0.006817 (rank : 59)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	64	Target Neighborhood Hits	321	Shared Neighborhood Hits	4
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

DG2L6_HUMAN
NC score	0.006533 (rank : 60)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	64	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZPD8, Q6IEE2	Gene names	DGAT2L6, DC3
Domain Architecture	No domain graphic available
Description	Diacylglycerol O-acyltransferase 2-like protein 6 (EC 2.3.1.-) (Diacylglycerol O-acyltransferase candidate 3) (hDC3).

MYST3_MOUSE
NC score	0.005962 (rank : 61)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	64	Target Neighborhood Hits	688	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BZ21, Q8BW52, Q8BYH1, Q8C1F3	Gene names	Myst3, Moz
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Monocytic leukemia zinc finger protein) (Monocytic leukemia zinc finger homolog).

MYH3_HUMAN
NC score	0.004967 (rank : 62)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	64	Target Neighborhood Hits	1660	Shared Neighborhood Hits	15
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

TBC14_HUMAN
NC score	0.004910 (rank : 63)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	64	Target Neighborhood Hits	124	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2M4, Q8IW15	Gene names	TBC1D14, KIAA1322
Domain Architecture
Description	TBC1 domain family member 14.

DAZP1_MOUSE
NC score	0.004899 (rank : 64)	θ value	4.03905 (rank : 51)
Query Neighborhood Hits	64	Target Neighborhood Hits	313	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JII5	Gene names	Dazap1
Domain Architecture
Description	DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1).

MYH13_HUMAN
NC score	0.004817 (rank : 65)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	64	Target Neighborhood Hits	1504	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

ITA5_HUMAN
NC score	0.004064 (rank : 66)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	64	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	P08648, Q96HA5	Gene names	ITGA5, FNRA
Domain Architecture
Description	Integrin alpha-5 precursor (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD49e antigen) [Contains: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain].

DAZP1_HUMAN
NC score	0.003497 (rank : 67)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	64	Target Neighborhood Hits	313	Shared Neighborhood Hits	3
SwissProt Accessions	Q96EP5, Q96MJ3, Q9NRR9	Gene names	DAZAP1
Domain Architecture
Description	DAZ-associated protein 1 (Deleted in azoospermia-associated protein 1).

GCC2_MOUSE
NC score	0.002382 (rank : 68)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	64	Target Neighborhood Hits	1619	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

AT11A_MOUSE
NC score	0.002262 (rank : 69)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	64	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	P98197	Gene names	Atp11a
Domain Architecture
Description	Probable phospholipid-transporting ATPase IH (EC 3.6.3.1) (ATPase class I type 11A) (ATPase IS).

REST_MOUSE
NC score	0.001498 (rank : 70)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	64	Target Neighborhood Hits	1506	Shared Neighborhood Hits	14
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

TNK1_HUMAN
NC score	-0.002042 (rank : 71)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	64	Target Neighborhood Hits	815	Shared Neighborhood Hits	2
SwissProt Accessions	Q13470, O95364, Q8IYI4	Gene names	TNK1
Domain Architecture	No domain graphic available
Description	Non-receptor tyrosine-protein kinase TNK1 (EC 2.7.10.2) (CD38 negative kinase 1).