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Network neighborhood for query Sequence : CALB2_MOUSE

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CALB2_MOUSE
SwissProt Accessions	Q08331, Q60964, Q9JM81	Gene names	Calb2
Domain Architecture
Description	Calretinin (CR).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CALB2_MOUSE
θ value	7.52544e-156 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	141
SwissProt Accessions	Q08331, Q60964, Q9JM81	Gene names	Calb2
Domain Architecture
Description	Calretinin (CR).

CALB2_HUMAN
θ value	2.04937e-153 (rank : 2)	NC score	0.996682 (rank : 2)
Query Neighborhood Hits	141	Target Neighborhood Hits	149	Shared Neighborhood Hits	139
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

CALB1_HUMAN
θ value	6.71607e-88 (rank : 3)	NC score	0.948173 (rank : 4)
Query Neighborhood Hits	141	Target Neighborhood Hits	130	Shared Neighborhood Hits	98
SwissProt Accessions	P05937	Gene names	CALB1, CAB27
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K).

CALB1_MOUSE
θ value	1.2666e-86 (rank : 4)	NC score	0.948254 (rank : 3)
Query Neighborhood Hits	141	Target Neighborhood Hits	129	Shared Neighborhood Hits	97
SwissProt Accessions	P12658, Q545N6	Gene names	Calb1
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K) (Spot 35 protein) (PCD-29).

SEGN_HUMAN
θ value	2.67181e-44 (rank : 5)	NC score	0.874051 (rank : 5)
Query Neighborhood Hits	141	Target Neighborhood Hits	96	Shared Neighborhood Hits	73
SwissProt Accessions	O76038, Q5VV44, Q96QV7, Q9UJF6	Gene names	SCGN, SECRET
Domain Architecture
Description	Secretagogin.

SEGN_MOUSE
θ value	1.51715e-39 (rank : 6)	NC score	0.855200 (rank : 6)
Query Neighborhood Hits	141	Target Neighborhood Hits	101	Shared Neighborhood Hits	78
SwissProt Accessions	Q91WD9	Gene names	Scgn
Domain Architecture
Description	Secretagogin.

CALM_HUMAN
θ value	4.0297e-08 (rank : 7)	NC score	0.469998 (rank : 13)
Query Neighborhood Hits	141	Target Neighborhood Hits	232	Shared Neighborhood Hits	115
SwissProt Accessions	P62158, P02593, P70667, P99014, Q13942, Q53S29, Q61379, Q61380, Q96HK3	Gene names	CALM1, CALM, CAM, CAM1
Domain Architecture
Description	Calmodulin (CaM).

CALM_MOUSE
θ value	4.0297e-08 (rank : 8)	NC score	0.469998 (rank : 14)
Query Neighborhood Hits	141	Target Neighborhood Hits	232	Shared Neighborhood Hits	115
SwissProt Accessions	P62204, P02593, P70667, P99014, Q61379, Q61380	Gene names	Calm1, Calm, Cam, Cam1
Domain Architecture
Description	Calmodulin (CaM).

CALL3_HUMAN
θ value	8.97725e-08 (rank : 9)	NC score	0.471588 (rank : 12)
Query Neighborhood Hits	141	Target Neighborhood Hits	225	Shared Neighborhood Hits	113
SwissProt Accessions	P27482	Gene names	CALML3
Domain Architecture
Description	Calmodulin-like protein 3 (Calmodulin-related protein NB-1) (CaM-like protein) (CLP).

CALL5_HUMAN
θ value	5.81887e-07 (rank : 10)	NC score	0.492669 (rank : 7)
Query Neighborhood Hits	141	Target Neighborhood Hits	231	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NZT1, Q8IXU8	Gene names	CALML5, CLSP
Domain Architecture
Description	Calmodulin-like protein 5 (Calmodulin-like skin protein).

CALM4_MOUSE
θ value	8.40245e-06 (rank : 11)	NC score	0.490339 (rank : 8)
Query Neighborhood Hits	141	Target Neighborhood Hits	229	Shared Neighborhood Hits	118
SwissProt Accessions	Q9JM83, Q9CR31, Q9D1E9	Gene names	Calm4, Dd112
Domain Architecture
Description	Calmodulin-4 (Calcium-binding protein Dd112).

HPCA_HUMAN
θ value	8.40245e-06 (rank : 12)	NC score	0.405657 (rank : 42)
Query Neighborhood Hits	141	Target Neighborhood Hits	156	Shared Neighborhood Hits	103
SwissProt Accessions	P84074, P32076, P41211, P70510	Gene names	HPCA, BDR2
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin (Calcium-binding protein BDR-2).

HPCA_MOUSE
θ value	8.40245e-06 (rank : 13)	NC score	0.405657 (rank : 43)
Query Neighborhood Hits	141	Target Neighborhood Hits	156	Shared Neighborhood Hits	103
SwissProt Accessions	P84075, P32076, P41211, P70510	Gene names	Hpca
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin.

CABP1_HUMAN
θ value	1.09739e-05 (rank : 14)	NC score	0.452861 (rank : 20)
Query Neighborhood Hits	141	Target Neighborhood Hits	197	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NZU7, O95663, Q9NZU8	Gene names	CABP1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1) (Calbrain).

CABP1_MOUSE
θ value	1.09739e-05 (rank : 15)	NC score	0.452931 (rank : 19)
Query Neighborhood Hits	141	Target Neighborhood Hits	197	Shared Neighborhood Hits	103
SwissProt Accessions	Q9JLK7, Q9JLK6	Gene names	Cabp1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1).

PLSL_MOUSE
θ value	1.09739e-05 (rank : 16)	NC score	0.326793 (rank : 65)
Query Neighborhood Hits	141	Target Neighborhood Hits	170	Shared Neighborhood Hits	81
SwissProt Accessions	Q61233, Q3UE24, Q8R1X3, Q9CV77	Gene names	Lcp1, Pls2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (pp65).

CETN1_HUMAN
θ value	1.87187e-05 (rank : 17)	NC score	0.456943 (rank : 16)
Query Neighborhood Hits	141	Target Neighborhood Hits	232	Shared Neighborhood Hits	112
SwissProt Accessions	Q12798	Gene names	CETN1, CEN1, CETN
Domain Architecture
Description	Centrin-1 (Caltractin isoform 2).

CETN2_HUMAN
θ value	1.87187e-05 (rank : 18)	NC score	0.450018 (rank : 21)
Query Neighborhood Hits	141	Target Neighborhood Hits	213	Shared Neighborhood Hits	112
SwissProt Accessions	P41208, Q53XW1	Gene names	CETN2, CALT, CEN2
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CETN1_MOUSE
θ value	2.44474e-05 (rank : 19)	NC score	0.443757 (rank : 25)
Query Neighborhood Hits	141	Target Neighborhood Hits	231	Shared Neighborhood Hits	111
SwissProt Accessions	P41209, Q3V119, Q9D9G9, Q9DAL6	Gene names	Cetn1, Calt
Domain Architecture
Description	Centrin-1 (Caltractin).

CETN2_MOUSE
θ value	2.44474e-05 (rank : 20)	NC score	0.446839 (rank : 23)
Query Neighborhood Hits	141	Target Neighborhood Hits	211	Shared Neighborhood Hits	111
SwissProt Accessions	Q9R1K9, Q3UBB4, Q9CWM0	Gene names	Cetn2, Calt
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

PLSI_HUMAN
θ value	2.44474e-05 (rank : 21)	NC score	0.367513 (rank : 56)
Query Neighborhood Hits	141	Target Neighborhood Hits	209	Shared Neighborhood Hits	96
SwissProt Accessions	Q14651	Gene names	PLS1
Domain Architecture
Description	Plastin-1 (I-plastin) (Intestine-specific plastin).

NCS1_HUMAN
θ value	3.19293e-05 (rank : 22)	NC score	0.382750 (rank : 50)
Query Neighborhood Hits	141	Target Neighborhood Hits	132	Shared Neighborhood Hits	97
SwissProt Accessions	P62166, P36610, Q9UK26	Gene names	FREQ, FLUP, NCS1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) (Frequenin-like protein) (Frequenin-like ubiquitous protein).

NCS1_MOUSE
θ value	3.19293e-05 (rank : 23)	NC score	0.382750 (rank : 51)
Query Neighborhood Hits	141	Target Neighborhood Hits	132	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BNY6	Gene names	Freq, Ncs1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog).

CABP4_HUMAN
θ value	4.1701e-05 (rank : 24)	NC score	0.446948 (rank : 22)
Query Neighborhood Hits	141	Target Neighborhood Hits	250	Shared Neighborhood Hits	112
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

CABP2_MOUSE
θ value	5.44631e-05 (rank : 25)	NC score	0.444619 (rank : 24)
Query Neighborhood Hits	141	Target Neighborhood Hits	204	Shared Neighborhood Hits	107
SwissProt Accessions	Q9JLK4, Q9JLK5	Gene names	Cabp2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

PLSL_HUMAN
θ value	5.44631e-05 (rank : 26)	NC score	0.318531 (rank : 69)
Query Neighborhood Hits	141	Target Neighborhood Hits	168	Shared Neighborhood Hits	82
SwissProt Accessions	P13796	Gene names	LCP1, PLS2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P).

TNNC2_MOUSE
θ value	5.44631e-05 (rank : 27)	NC score	0.487570 (rank : 9)
Query Neighborhood Hits	141	Target Neighborhood Hits	233	Shared Neighborhood Hits	118
SwissProt Accessions	P20801	Gene names	Tnnc2, Tncs
Domain Architecture
Description	Troponin C, skeletal muscle (STNC).

CABP2_HUMAN
θ value	9.29e-05 (rank : 28)	NC score	0.439944 (rank : 28)
Query Neighborhood Hits	141	Target Neighborhood Hits	205	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NPB3	Gene names	CABP2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

GUC1A_MOUSE
θ value	0.000121331 (rank : 29)	NC score	0.442280 (rank : 27)
Query Neighborhood Hits	141	Target Neighborhood Hits	152	Shared Neighborhood Hits	101
SwissProt Accessions	P43081	Gene names	Guca1a, Gcap, Gcap1, Guca1
Domain Architecture
Description	Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A).

HPCL1_MOUSE
θ value	0.000121331 (rank : 30)	NC score	0.405513 (rank : 44)
Query Neighborhood Hits	141	Target Neighborhood Hits	149	Shared Neighborhood Hits	103
SwissProt Accessions	P62748, P35333	Gene names	Hpcal1
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Neural visinin-like protein 3) (NVL-3) (NVP-3).

GUC1A_HUMAN
θ value	0.000158464 (rank : 31)	NC score	0.436961 (rank : 30)
Query Neighborhood Hits	141	Target Neighborhood Hits	147	Shared Neighborhood Hits	100
SwissProt Accessions	P43080, Q9NU14	Gene names	GUCA1A, GCAP, GCAP1, GUCA1
Domain Architecture
Description	Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A).

HPCL1_HUMAN
θ value	0.000158464 (rank : 32)	NC score	0.405428 (rank : 45)
Query Neighborhood Hits	141	Target Neighborhood Hits	150	Shared Neighborhood Hits	101
SwissProt Accessions	P37235, Q969S5	Gene names	HPCAL1, BDR1
Domain Architecture
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Calcium-binding protein BDR-1) (HLP2).

RCN3_MOUSE
θ value	0.000158464 (rank : 33)	NC score	0.225374 (rank : 101)
Query Neighborhood Hits	141	Target Neighborhood Hits	91	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BH97, Q58E50, Q8R137, Q99K35, Q9CTD4	Gene names	Rcn3, D7Ertd671e
Domain Architecture	No domain graphic available
Description	Reticulocalbin-3 precursor.

NCALD_HUMAN
θ value	0.00020696 (rank : 34)	NC score	0.406293 (rank : 38)
Query Neighborhood Hits	141	Target Neighborhood Hits	153	Shared Neighborhood Hits	102
SwissProt Accessions	P61601, P29554, Q8IYC3, Q9H0W2	Gene names	NCALD
Domain Architecture
Description	Neurocalcin delta.

NCALD_MOUSE
θ value	0.00020696 (rank : 35)	NC score	0.406293 (rank : 39)
Query Neighborhood Hits	141	Target Neighborhood Hits	153	Shared Neighborhood Hits	102
SwissProt Accessions	Q91X97, Q3TJS9, Q8BZN9	Gene names	Ncald, D15Ertd412e
Domain Architecture
Description	Neurocalcin delta.

TNNC2_HUMAN
θ value	0.00035302 (rank : 36)	NC score	0.480947 (rank : 10)
Query Neighborhood Hits	141	Target Neighborhood Hits	234	Shared Neighborhood Hits	118
SwissProt Accessions	P02585	Gene names	TNNC2
Domain Architecture
Description	Troponin C, skeletal muscle.

GUC1B_HUMAN
θ value	0.000461057 (rank : 37)	NC score	0.405131 (rank : 46)
Query Neighborhood Hits	141	Target Neighborhood Hits	124	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UMX6, Q9NU15	Gene names	GUCA1B, GCAP2
Domain Architecture
Description	Guanylyl cyclase-activating protein 2 (GCAP 2) (Guanylate cyclase activator 1B).

CANB2_HUMAN
θ value	0.000602161 (rank : 38)	NC score	0.464242 (rank : 15)
Query Neighborhood Hits	141	Target Neighborhood Hits	163	Shared Neighborhood Hits	104
SwissProt Accessions	Q96LZ3, Q7Z4V8, Q8WYJ4	Gene names	PPP3R2, CBLP
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform) (Calcineurin B-like protein) (CBLP) (CNBII).

CABP4_MOUSE
θ value	0.000786445 (rank : 39)	NC score	0.430704 (rank : 31)
Query Neighborhood Hits	141	Target Neighborhood Hits	212	Shared Neighborhood Hits	107
SwissProt Accessions	Q8VHC5	Gene names	Cabp4
Domain Architecture	No domain graphic available
Description	Calcium-binding protein 4 (CaBP4).

CANB1_HUMAN
θ value	0.00102713 (rank : 40)	NC score	0.456209 (rank : 17)
Query Neighborhood Hits	141	Target Neighborhood Hits	183	Shared Neighborhood Hits	109
SwissProt Accessions	P63098, P06705, P15117, Q08044	Gene names	PPP3R1, CNA2, CNB
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB1_MOUSE
θ value	0.00102713 (rank : 41)	NC score	0.456125 (rank : 18)
Query Neighborhood Hits	141	Target Neighborhood Hits	183	Shared Neighborhood Hits	109
SwissProt Accessions	Q63810	Gene names	Ppp3r1, Cnb
Domain Architecture
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB2_MOUSE
θ value	0.00134147 (rank : 42)	NC score	0.472365 (rank : 11)
Query Neighborhood Hits	141	Target Neighborhood Hits	173	Shared Neighborhood Hits	108
SwissProt Accessions	Q63811	Gene names	Ppp3r2
Domain Architecture
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform).

CABP5_HUMAN
θ value	0.00298849 (rank : 43)	NC score	0.422387 (rank : 34)
Query Neighborhood Hits	141	Target Neighborhood Hits	197	Shared Neighborhood Hits	110
SwissProt Accessions	Q9NP86	Gene names	CABP5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

PDCD6_MOUSE
θ value	0.00298849 (rank : 44)	NC score	0.342458 (rank : 60)
Query Neighborhood Hits	141	Target Neighborhood Hits	142	Shared Neighborhood Hits	96
SwissProt Accessions	P12815, Q545I0, Q61145	Gene names	Pdcd6, Alg2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2) (PMP41) (ALG-257).

MLR5_HUMAN
θ value	0.00390308 (rank : 45)	NC score	0.277922 (rank : 83)
Query Neighborhood Hits	141	Target Neighborhood Hits	90	Shared Neighborhood Hits	55
SwissProt Accessions	Q02045	Gene names	MYL5
Domain Architecture
Description	Superfast myosin regulatory light chain 2 (MyLC-2) (MYLC2) (Myosin regulatory light chain 5).

CETN3_HUMAN
θ value	0.00509761 (rank : 46)	NC score	0.429534 (rank : 33)
Query Neighborhood Hits	141	Target Neighborhood Hits	211	Shared Neighborhood Hits	114
SwissProt Accessions	O15182, Q9BS23	Gene names	CETN3, CEN3
Domain Architecture
Description	Centrin-3.

CETN3_MOUSE
θ value	0.00509761 (rank : 47)	NC score	0.430039 (rank : 32)
Query Neighborhood Hits	141	Target Neighborhood Hits	208	Shared Neighborhood Hits	114
SwissProt Accessions	O35648	Gene names	Cetn3, Cen3
Domain Architecture
Description	Centrin-3.

ONCO_HUMAN
θ value	0.00509761 (rank : 48)	NC score	0.395782 (rank : 48)
Query Neighborhood Hits	141	Target Neighborhood Hits	88	Shared Neighborhood Hits	66
SwissProt Accessions	P32930	Gene names	OCM, OCMN
Domain Architecture
Description	Oncomodulin (OM) (Parvalbumin beta).

PRVA_MOUSE
θ value	0.00869519 (rank : 49)	NC score	0.414257 (rank : 35)
Query Neighborhood Hits	141	Target Neighborhood Hits	77	Shared Neighborhood Hits	61
SwissProt Accessions	P32848	Gene names	Pvalb, Pva
Domain Architecture
Description	Parvalbumin alpha.

RCN3_HUMAN
θ value	0.00869519 (rank : 50)	NC score	0.214130 (rank : 103)
Query Neighborhood Hits	141	Target Neighborhood Hits	89	Shared Neighborhood Hits	64
SwissProt Accessions	Q96D15, Q9HBZ8	Gene names	RCN3
Domain Architecture
Description	Reticulocalbin-3 precursor (EF-hand calcium-binding protein RLP49).

CABP5_MOUSE
θ value	0.0113563 (rank : 51)	NC score	0.413271 (rank : 36)
Query Neighborhood Hits	141	Target Neighborhood Hits	207	Shared Neighborhood Hits	114
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

PKD2_MOUSE
θ value	0.0113563 (rank : 52)	NC score	0.093618 (rank : 171)
Query Neighborhood Hits	141	Target Neighborhood Hits	99	Shared Neighborhood Hits	19
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

ONCO_MOUSE
θ value	0.0148317 (rank : 53)	NC score	0.396394 (rank : 47)
Query Neighborhood Hits	141	Target Neighborhood Hits	98	Shared Neighborhood Hits	72
SwissProt Accessions	P51879, Q62004	Gene names	Ocm
Domain Architecture
Description	Oncomodulin (OM) (Parvalbumin beta).

PDCD6_HUMAN
θ value	0.0148317 (rank : 54)	NC score	0.337968 (rank : 61)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	96
SwissProt Accessions	O75340	Gene names	PDCD6, ALG2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2).

PKD2_HUMAN
θ value	0.0148317 (rank : 55)	NC score	0.094606 (rank : 169)
Query Neighborhood Hits	141	Target Neighborhood Hits	105	Shared Neighborhood Hits	17
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

RCN2_MOUSE
θ value	0.0148317 (rank : 56)	NC score	0.267155 (rank : 90)
Query Neighborhood Hits	141	Target Neighborhood Hits	108	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BP92, O70341	Gene names	Rcn2
Domain Architecture	No domain graphic available
Description	Reticulocalbin-2 precursor (Taipoxin-associated calcium-binding protein 49) (TCBP-49).

RECO_MOUSE
θ value	0.0193708 (rank : 57)	NC score	0.335685 (rank : 62)
Query Neighborhood Hits	141	Target Neighborhood Hits	108	Shared Neighborhood Hits	73
SwissProt Accessions	P34057	Gene names	Rcvrn, Rcv1
Domain Architecture
Description	Recoverin (Cancer-associated retinopathy protein) (Protein CAR) (23 kDa photoreceptor cell-specific protein).

GUC1B_MOUSE
θ value	0.0252991 (rank : 58)	NC score	0.377179 (rank : 53)
Query Neighborhood Hits	141	Target Neighborhood Hits	116	Shared Neighborhood Hits	81
SwissProt Accessions	Q8VBV8	Gene names	Guca1b
Domain Architecture	No domain graphic available
Description	Guanylyl cyclase-activating protein 2 (GCAP 2) (Guanylate cyclase activator 1B).

PEF1_MOUSE
θ value	0.0252991 (rank : 59)	NC score	0.214039 (rank : 104)
Query Neighborhood Hits	141	Target Neighborhood Hits	112	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BFY6, Q8VCT5, Q9CYW8, Q9D934	Gene names	Pef1
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

CAN1_HUMAN
θ value	0.0330416 (rank : 60)	NC score	0.104211 (rank : 160)
Query Neighborhood Hits	141	Target Neighborhood Hits	85	Shared Neighborhood Hits	54
SwissProt Accessions	P07384	Gene names	CAPN1, CANPL1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

FA8_HUMAN
θ value	0.0330416 (rank : 61)	NC score	0.047764 (rank : 212)
Query Neighborhood Hits	141	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

DJBP_MOUSE
θ value	0.0563607 (rank : 62)	NC score	0.195188 (rank : 115)
Query Neighborhood Hits	141	Target Neighborhood Hits	152	Shared Neighborhood Hits	65
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

PLST_HUMAN
θ value	0.0563607 (rank : 63)	NC score	0.269267 (rank : 85)
Query Neighborhood Hits	141	Target Neighborhood Hits	161	Shared Neighborhood Hits	83
SwissProt Accessions	P13797, Q86YI6	Gene names	PLS3
Domain Architecture
Description	Plastin-3 (T-plastin).

PLST_MOUSE
θ value	0.0563607 (rank : 64)	NC score	0.267797 (rank : 88)
Query Neighborhood Hits	141	Target Neighborhood Hits	156	Shared Neighborhood Hits	78
SwissProt Accessions	Q99K51	Gene names	Pls3
Domain Architecture	No domain graphic available
Description	Plastin-3 (T-plastin).

RCN2_HUMAN
θ value	0.0563607 (rank : 65)	NC score	0.234811 (rank : 97)
Query Neighborhood Hits	141	Target Neighborhood Hits	95	Shared Neighborhood Hits	72
SwissProt Accessions	Q14257	Gene names	RCN2, ERC55
Domain Architecture
Description	Reticulocalbin-2 precursor (Calcium-binding protein ERC-55) (E6- binding protein) (E6BP).

SPTA2_HUMAN
θ value	0.0563607 (rank : 66)	NC score	0.129020 (rank : 143)
Query Neighborhood Hits	141	Target Neighborhood Hits	888	Shared Neighborhood Hits	82
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

DGKB_HUMAN
θ value	0.0736092 (rank : 67)	NC score	0.191659 (rank : 120)
Query Neighborhood Hits	141	Target Neighborhood Hits	238	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

PRVA_HUMAN
θ value	0.0736092 (rank : 68)	NC score	0.382197 (rank : 52)
Query Neighborhood Hits	141	Target Neighborhood Hits	63	Shared Neighborhood Hits	55
SwissProt Accessions	P20472, P78378, Q4VB78, Q5R3Q9	Gene names	PVALB
Domain Architecture	No domain graphic available
Description	Parvalbumin alpha.

KCIP4_MOUSE
θ value	0.125558 (rank : 69)	NC score	0.314731 (rank : 71)
Query Neighborhood Hits	141	Target Neighborhood Hits	136	Shared Neighborhood Hits	88
SwissProt Accessions	Q6PHZ8, Q6DTJ3, Q8CAD0, Q8R4I2, Q9EQ01	Gene names	Kcnip4, Calp, Kchip4
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Potassium channel-interacting protein 4) (Calsenilin-like protein).

RECO_HUMAN
θ value	0.125558 (rank : 70)	NC score	0.323965 (rank : 68)
Query Neighborhood Hits	141	Target Neighborhood Hits	101	Shared Neighborhood Hits	66
SwissProt Accessions	P35243	Gene names	RCVRN, RCV1
Domain Architecture
Description	Recoverin (Cancer-associated retinopathy protein) (Protein CAR).

DGKA_MOUSE
θ value	0.163984 (rank : 71)	NC score	0.138072 (rank : 141)
Query Neighborhood Hits	141	Target Neighborhood Hits	146	Shared Neighborhood Hits	62
SwissProt Accessions	O88673, Q922X2	Gene names	Dgka, Dagk1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

CABP7_HUMAN
θ value	0.21417 (rank : 72)	NC score	0.406046 (rank : 40)
Query Neighborhood Hits	141	Target Neighborhood Hits	205	Shared Neighborhood Hits	110
SwissProt Accessions	Q86V35	Gene names	CABP7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CABP7_MOUSE
θ value	0.21417 (rank : 73)	NC score	0.406046 (rank : 41)
Query Neighborhood Hits	141	Target Neighborhood Hits	205	Shared Neighborhood Hits	110
SwissProt Accessions	Q91ZM8	Gene names	Cabp7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

SPTA1_HUMAN
θ value	0.21417 (rank : 74)	NC score	0.063069 (rank : 197)
Query Neighborhood Hits	141	Target Neighborhood Hits	748	Shared Neighborhood Hits	32
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

DGKA_HUMAN
θ value	0.279714 (rank : 75)	NC score	0.114038 (rank : 156)
Query Neighborhood Hits	141	Target Neighborhood Hits	151	Shared Neighborhood Hits	52
SwissProt Accessions	P23743, O75481, O75482, O75483	Gene names	DGKA, DAGK, DAGK1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

GUC1C_HUMAN
θ value	0.279714 (rank : 76)	NC score	0.412171 (rank : 37)
Query Neighborhood Hits	141	Target Neighborhood Hits	148	Shared Neighborhood Hits	96
SwissProt Accessions	O95843, O95844, Q9UNM0	Gene names	GUCA1C, GCAP3
Domain Architecture
Description	Guanylyl cyclase-activating protein 3 (GCAP 3) (Guanylate cyclase activator 1C).

HPCL4_HUMAN
θ value	0.279714 (rank : 77)	NC score	0.332484 (rank : 64)
Query Neighborhood Hits	141	Target Neighborhood Hits	123	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UM19, Q5TG97, Q8N611	Gene names	HPCAL4
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 4 (HLP4).

HPCL4_MOUSE
θ value	0.279714 (rank : 78)	NC score	0.332534 (rank : 63)
Query Neighborhood Hits	141	Target Neighborhood Hits	123	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BGZ1	Gene names	Hpcal4
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 4 (Neural visinin-like protein 2) (NVP-2).

VISL1_HUMAN
θ value	0.279714 (rank : 79)	NC score	0.326028 (rank : 66)
Query Neighborhood Hits	141	Target Neighborhood Hits	124	Shared Neighborhood Hits	87
SwissProt Accessions	P62760, P28677, P29103, P42323, Q9UM20	Gene names	VSNL1, VISL1
Domain Architecture	No domain graphic available
Description	Visinin-like protein 1 (VILIP) (Hippocalcin-like protein 3) (HLP3).

VISL1_MOUSE
θ value	0.279714 (rank : 80)	NC score	0.326028 (rank : 67)
Query Neighborhood Hits	141	Target Neighborhood Hits	124	Shared Neighborhood Hits	87
SwissProt Accessions	P62761, P28677, P29103, P42323, Q9UM20	Gene names	Vsnl1, Visl1
Domain Architecture	No domain graphic available
Description	Visinin-like protein 1 (VILIP) (Neural visinin-like protein 1) (NVL-1) (NVP-1).

FA8_MOUSE
θ value	0.365318 (rank : 81)	NC score	0.040531 (rank : 213)
Query Neighborhood Hits	141	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

KCIP4_HUMAN
θ value	0.365318 (rank : 82)	NC score	0.311120 (rank : 72)
Query Neighborhood Hits	141	Target Neighborhood Hits	136	Shared Neighborhood Hits	88
SwissProt Accessions	Q6PIL6, Q4W5G8, Q8NEU0, Q9BWT2, Q9H294, Q9H2A4	Gene names	KCNIP4, CALP, KCHIP4
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Potassium channel-interacting protein 4) (Calsenilin-like protein).

MACF1_HUMAN
θ value	0.365318 (rank : 83)	NC score	0.082307 (rank : 187)
Query Neighborhood Hits	141	Target Neighborhood Hits	1341	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	0.365318 (rank : 84)	NC score	0.082536 (rank : 186)
Query Neighborhood Hits	141	Target Neighborhood Hits	1321	Shared Neighborhood Hits	85
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MCFD2_HUMAN
θ value	0.365318 (rank : 85)	NC score	0.176503 (rank : 129)
Query Neighborhood Hits	141	Target Neighborhood Hits	62	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NI22, Q8N3M5	Gene names	MCFD2, SDNSF
Domain Architecture
Description	Multiple coagulation factor deficiency protein 2 precursor (Neural stem cell-derived neuronal survival protein).

CALL6_HUMAN
θ value	0.47712 (rank : 86)	NC score	0.367813 (rank : 55)
Query Neighborhood Hits	141	Target Neighborhood Hits	157	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TD86, Q6Q2C4	Gene names	CALML6, CAGLP, CALGP
Domain Architecture	No domain graphic available
Description	Calmodulin-like protein 6 (Calglandulin-like protein).

KIP2_HUMAN
θ value	0.47712 (rank : 87)	NC score	0.292119 (rank : 77)
Query Neighborhood Hits	141	Target Neighborhood Hits	107	Shared Neighborhood Hits	78
SwissProt Accessions	O75838	Gene names	CIB2, KIP2
Domain Architecture	No domain graphic available
Description	Calcium and integrin-binding protein 2 (Kinase-interacting protein 2) (KIP 2).

MLRV_MOUSE
θ value	0.47712 (rank : 88)	NC score	0.239937 (rank : 95)
Query Neighborhood Hits	141	Target Neighborhood Hits	89	Shared Neighborhood Hits	56
SwissProt Accessions	P51667	Gene names	Myl2, Mylpc
Domain Architecture
Description	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v).

BPA1_MOUSE
θ value	0.813845 (rank : 89)	NC score	0.077756 (rank : 189)
Query Neighborhood Hits	141	Target Neighborhood Hits	1477	Shared Neighborhood Hits	86
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_HUMAN
θ value	0.813845 (rank : 90)	NC score	0.075589 (rank : 190)
Query Neighborhood Hits	141	Target Neighborhood Hits	1369	Shared Neighborhood Hits	82
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

KCIP1_HUMAN
θ value	0.813845 (rank : 91)	NC score	0.294540 (rank : 75)
Query Neighborhood Hits	141	Target Neighborhood Hits	113	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NZI2, Q5U822	Gene names	KCNIP1, KCHIP1, VABP
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1) (Vesicle APC-binding protein).

KCIP1_MOUSE
θ value	0.813845 (rank : 92)	NC score	0.294235 (rank : 76)
Query Neighborhood Hits	141	Target Neighborhood Hits	113	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JJ57, Q5SSA3, Q6DTJ1, Q8BGJ4, Q8C4K4, Q8CGL1, Q8K1U1, Q8K3M2	Gene names	Kcnip1, Kchip1
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1).

MACF1_MOUSE
θ value	0.813845 (rank : 93)	NC score	0.083788 (rank : 183)
Query Neighborhood Hits	141	Target Neighborhood Hits	1313	Shared Neighborhood Hits	89
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MCFD2_MOUSE
θ value	0.813845 (rank : 94)	NC score	0.161688 (rank : 135)
Query Neighborhood Hits	141	Target Neighborhood Hits	61	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K5B2, Q3U9G5	Gene names	Mcfd2, Sdnsf
Domain Architecture
Description	Multiple coagulation factor deficiency protein 2 homolog precursor (Neural stem cell-derived neuronal survival protein).

RCN1_HUMAN
θ value	0.813845 (rank : 95)	NC score	0.185293 (rank : 126)
Query Neighborhood Hits	141	Target Neighborhood Hits	105	Shared Neighborhood Hits	71
SwissProt Accessions	Q15293	Gene names	RCN1, RCN
Domain Architecture
Description	Reticulocalbin-1 precursor.

DJBP_HUMAN
θ value	1.06291 (rank : 96)	NC score	0.158393 (rank : 137)
Query Neighborhood Hits	141	Target Neighborhood Hits	156	Shared Neighborhood Hits	54
SwissProt Accessions	Q5THR3, Q5U5T6, Q9BY88, Q9H5C4, Q9NSF5	Gene names	DJBP, KIAA1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein (CAP-binding protein complex-interacting protein 1).

EFCB1_MOUSE
θ value	1.06291 (rank : 97)	NC score	0.370095 (rank : 54)
Query Neighborhood Hits	141	Target Neighborhood Hits	126	Shared Neighborhood Hits	87
SwissProt Accessions	Q9D3N2, Q8BSW3, Q8C982, Q8CAI0, Q9D527, Q9D5E7	Gene names	Efcab1
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 1.

KIP2_MOUSE
θ value	1.06291 (rank : 98)	NC score	0.287123 (rank : 78)
Query Neighborhood Hits	141	Target Neighborhood Hits	110	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z309	Gene names	Cib2, Kip2
Domain Architecture	No domain graphic available
Description	Calcium and integrin-binding protein 2 (Kinase-interacting protein 2) (KIP 2).

MLRV_HUMAN
θ value	1.06291 (rank : 99)	NC score	0.235788 (rank : 96)
Query Neighborhood Hits	141	Target Neighborhood Hits	89	Shared Neighborhood Hits	55
SwissProt Accessions	P10916, Q16123	Gene names	MYL2
Domain Architecture
Description	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v).

CABP3_HUMAN
θ value	1.38821 (rank : 100)	NC score	0.384359 (rank : 49)
Query Neighborhood Hits	141	Target Neighborhood Hits	162	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NZU6, Q9NYY0, Q9NZT9	Gene names	CABP3
Domain Architecture
Description	Calcium-binding protein 3 (CaBP3).

CSEN_HUMAN
θ value	1.38821 (rank : 101)	NC score	0.308040 (rank : 73)
Query Neighborhood Hits	141	Target Neighborhood Hits	128	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y2W7, Q53TJ5, Q96T40, Q9UJ84, Q9UJ85	Gene names	KCNIP3, CSEN, DREAM, KCHIP3
Domain Architecture
Description	Calsenilin (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3) (A-type potassium channel modulatory protein 3).

FRAS1_MOUSE
θ value	1.38821 (rank : 102)	NC score	0.009015 (rank : 228)
Query Neighborhood Hits	141	Target Neighborhood Hits	747	Shared Neighborhood Hits	4
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

TNNC1_MOUSE
θ value	1.38821 (rank : 103)	NC score	0.442599 (rank : 26)
Query Neighborhood Hits	141	Target Neighborhood Hits	221	Shared Neighborhood Hits	118
SwissProt Accessions	P19123	Gene names	Tnnc1, Tncc
Domain Architecture
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

CALN1_HUMAN
θ value	1.81305 (rank : 104)	NC score	0.356580 (rank : 58)
Query Neighborhood Hits	141	Target Neighborhood Hits	161	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BXU9	Gene names	CALN1, CABP8
Domain Architecture
Description	Calneuron-1 (Calcium-binding protein CaBP8).

CALN1_MOUSE
θ value	1.81305 (rank : 105)	NC score	0.356046 (rank : 59)
Query Neighborhood Hits	141	Target Neighborhood Hits	161	Shared Neighborhood Hits	91
SwissProt Accessions	Q9JJG7	Gene names	Caln1
Domain Architecture
Description	Calneuron-1.

CPNS1_MOUSE
θ value	1.81305 (rank : 106)	NC score	0.115337 (rank : 154)
Query Neighborhood Hits	141	Target Neighborhood Hits	60	Shared Neighborhood Hits	40
SwissProt Accessions	O88456, Q3V0X5, Q5BKQ2, Q8CEI2, Q8VEK4, Q9R1C5	Gene names	Capns1, Capn4
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

EFCB1_HUMAN
θ value	1.81305 (rank : 107)	NC score	0.357996 (rank : 57)
Query Neighborhood Hits	141	Target Neighborhood Hits	121	Shared Neighborhood Hits	86
SwissProt Accessions	Q9HAE3	Gene names	EFCAB1
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 1.

EFHD1_MOUSE
θ value	1.81305 (rank : 108)	NC score	0.232659 (rank : 98)
Query Neighborhood Hits	141	Target Neighborhood Hits	108	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D4J1, Q543U4	Gene names	Efhd1, Sws2
Domain Architecture
Description	EF-hand domain-containing protein 1 (Swiprosin-2).

TNNC1_HUMAN
θ value	1.81305 (rank : 109)	NC score	0.439485 (rank : 29)
Query Neighborhood Hits	141	Target Neighborhood Hits	219	Shared Neighborhood Hits	118
SwissProt Accessions	P63316, O14800, P02590, P04463	Gene names	TNNC1, TNNC
Domain Architecture	No domain graphic available
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

CAN1_MOUSE
θ value	2.36792 (rank : 110)	NC score	0.098404 (rank : 166)
Query Neighborhood Hits	141	Target Neighborhood Hits	83	Shared Neighborhood Hits	47
SwissProt Accessions	O35350, O88666	Gene names	Capn1, Canp1, Capa1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

NOX5_HUMAN
θ value	2.36792 (rank : 111)	NC score	0.147489 (rank : 140)
Query Neighborhood Hits	141	Target Neighborhood Hits	89	Shared Neighborhood Hits	55
SwissProt Accessions	Q96PH1, Q8TEQ1, Q8TER4, Q96PH2, Q96PJ8, Q96PJ9, Q9H6E0, Q9HAM8	Gene names	NOX5
Domain Architecture	No domain graphic available
Description	NADPH oxidase 5 (EC 1.6.3.-).

PK2L1_HUMAN
θ value	2.36792 (rank : 112)	NC score	0.050738 (rank : 210)
Query Neighborhood Hits	141	Target Neighborhood Hits	132	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

SCN7A_HUMAN
θ value	2.36792 (rank : 113)	NC score	0.027071 (rank : 217)
Query Neighborhood Hits	141	Target Neighborhood Hits	135	Shared Neighborhood Hits	16
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

CPNS1_HUMAN
θ value	3.0926 (rank : 114)	NC score	0.105469 (rank : 159)
Query Neighborhood Hits	141	Target Neighborhood Hits	57	Shared Neighborhood Hits	37
SwissProt Accessions	P04632, Q8WTX3, Q96EW0	Gene names	CAPNS1, CAPN4, CAPNS
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

DUOX1_HUMAN
θ value	3.0926 (rank : 115)	NC score	0.202844 (rank : 108)
Query Neighborhood Hits	141	Target Neighborhood Hits	172	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NRD9, Q6ZMB3, Q6ZR09, Q9NZC1	Gene names	DUOX1, DUOX, LNOX1, THOX1
Domain Architecture	No domain graphic available
Description	Dual oxidase 1 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH thyroid oxidase 1) (Thyroid oxidase 1) (Large NOX 1) (Long NOX 1).

EFHC1_MOUSE
θ value	3.0926 (rank : 116)	NC score	0.086264 (rank : 181)
Query Neighborhood Hits	141	Target Neighborhood Hits	65	Shared Neighborhood Hits	44
SwissProt Accessions	Q9D9T8	Gene names	Efhc1
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing protein 1.

EFHD2_MOUSE
θ value	3.0926 (rank : 117)	NC score	0.193912 (rank : 118)
Query Neighborhood Hits	141	Target Neighborhood Hits	88	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D8Y0, Q9D0P4	Gene names	Efhd2, Sws1
Domain Architecture
Description	EF-hand domain-containing protein 2 (Swiprosin-1).

FKB10_MOUSE
θ value	3.0926 (rank : 118)	NC score	0.050362 (rank : 211)
Query Neighborhood Hits	141	Target Neighborhood Hits	66	Shared Neighborhood Hits	32
SwissProt Accessions	Q61576, Q8VHI1	Gene names	Fkbp10, Fkbp-rs, Fkbp1-rs, Fkbp6, Fkbprp
Domain Architecture
Description	FK506-binding protein 10 precursor (EC 5.2.1.8) (Peptidyl-prolyl cis- trans isomerase) (PPIase) (Rotamase) (65 kDa FK506-binding protein) (FKBP65) (Immunophilin FKBP65).

KTN1_MOUSE
θ value	3.0926 (rank : 119)	NC score	0.010458 (rank : 227)
Query Neighborhood Hits	141	Target Neighborhood Hits	1324	Shared Neighborhood Hits	14
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

MYL6B_MOUSE
θ value	3.0926 (rank : 120)	NC score	0.209767 (rank : 105)
Query Neighborhood Hits	141	Target Neighborhood Hits	68	Shared Neighborhood Hits	39
SwissProt Accessions	Q8CI43	Gene names	Myl6b
Domain Architecture	No domain graphic available
Description	Myosin light polypeptide 6B (Smooth muscle and nonmuscle myosin light chain alkali 6B).

PEF1_HUMAN
θ value	3.0926 (rank : 121)	NC score	0.168916 (rank : 133)
Query Neighborhood Hits	141	Target Neighborhood Hits	135	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

CAN2_HUMAN
θ value	4.03905 (rank : 122)	NC score	0.059261 (rank : 200)
Query Neighborhood Hits	141	Target Neighborhood Hits	71	Shared Neighborhood Hits	32
SwissProt Accessions	P17655, Q16738, Q6PJT3, Q8WU26, Q9HBB1	Gene names	CAPN2, CANPL2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (Calpain large polypeptide L2).

CSEN_MOUSE
θ value	4.03905 (rank : 123)	NC score	0.286252 (rank : 79)
Query Neighborhood Hits	141	Target Neighborhood Hits	117	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QXT8, Q924L0, Q99PH9, Q99PI0, Q99PI2, Q99PI3, Q9JHZ5	Gene names	Kcnip3, Csen, Dream, Kchip3
Domain Architecture
Description	Calsenilin (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (A-type potassium channel modulatory protein 3) (KChIP3).

FKBP9_MOUSE
θ value	4.03905 (rank : 124)	NC score	0.063367 (rank : 196)
Query Neighborhood Hits	141	Target Neighborhood Hits	77	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z247, Q80ZZ6, Q8R386, Q9CVM0, Q9JHX5	Gene names	Fkbp9, Fkbp60, Fkbp63
Domain Architecture
Description	FK506-binding protein 9 precursor (EC 5.2.1.8) (Peptidyl-prolyl cis- trans isomerase) (PPIase) (Rotamase) (FKBP65RS).

RCN1_MOUSE
θ value	5.27518 (rank : 125)	NC score	0.160461 (rank : 136)
Query Neighborhood Hits	141	Target Neighborhood Hits	91	Shared Neighborhood Hits	62
SwissProt Accessions	Q05186, Q3TVU3	Gene names	Rcn1, Rca1, Rcn
Domain Architecture
Description	Reticulocalbin-1 precursor.

2ACC_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.020995 (rank : 218)
Query Neighborhood Hits	141	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5P8	Gene names	PPP2R3B, PPP2R3L
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 48 kDa regulatory subunit B (PP2A, subunit B, PR48 isoform).

DUOX2_HUMAN
θ value	6.88961 (rank : 127)	NC score	0.199581 (rank : 110)
Query Neighborhood Hits	141	Target Neighborhood Hits	139	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NRD8, Q9NR02, Q9UHF9	Gene names	DUOX2, LNOX2, THOX2
Domain Architecture	No domain graphic available
Description	Dual oxidase 2 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH oxidase/peroxidase DUOX2) (NADPH thyroid oxidase 2) (Thyroid oxidase 2) (NADH/NADPH thyroid oxidase p138-tox) (p138 thyroid oxidase) (Large NOX 2) (Long NOX 2).

FKBP7_MOUSE
θ value	6.88961 (rank : 128)	NC score	0.039839 (rank : 215)
Query Neighborhood Hits	141	Target Neighborhood Hits	58	Shared Neighborhood Hits	25
SwissProt Accessions	O54998	Gene names	Fkbp7, Fkbp23
Domain Architecture
Description	FK506-binding protein 7 precursor (EC 5.2.1.8) (Peptidyl-prolyl cis- trans isomerase) (PPIase) (Rotamase) (FKBP-23).

GOGA4_HUMAN
θ value	6.88961 (rank : 129)	NC score	0.011438 (rank : 226)
Query Neighborhood Hits	141	Target Neighborhood Hits	2034	Shared Neighborhood Hits	20
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MYL6B_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.215189 (rank : 102)
Query Neighborhood Hits	141	Target Neighborhood Hits	78	Shared Neighborhood Hits	44
SwissProt Accessions	P14649	Gene names	MYL6B, MLC1SA
Domain Architecture
Description	Myosin light polypeptide 6B (Smooth muscle and nonmuscle myosin light chain alkali 6B) (Myosin light chain 1 slow-twitch muscle A isoform) (MLC1sa).

TBC19_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.017312 (rank : 225)
Query Neighborhood Hits	141	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N5T2	Gene names	TBC1D19
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 19.

CHP2_MOUSE
θ value	8.99809 (rank : 132)	NC score	0.295534 (rank : 74)
Query Neighborhood Hits	141	Target Neighborhood Hits	122	Shared Neighborhood Hits	87
SwissProt Accessions	Q9D869	Gene names	Chp2, Hca520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520 homolog).

FKB10_HUMAN
θ value	8.99809 (rank : 133)	NC score	0.040376 (rank : 214)
Query Neighborhood Hits	141	Target Neighborhood Hits	61	Shared Neighborhood Hits	28
SwissProt Accessions	Q96AY3, Q7Z3R4, Q9H3N3, Q9H6N5, Q9UF89	Gene names	FKBP10, FKBP65
Domain Architecture
Description	FK506-binding protein 10 precursor (EC 5.2.1.8) (Peptidyl-prolyl cis- trans isomerase) (PPIase) (Rotamase) (65 kDa FK506-binding protein) (FKBP65) (Immunophilin FKBP65).

GCC1_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.006468 (rank : 229)
Query Neighborhood Hits	141	Target Neighborhood Hits	777	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

PLCD1_HUMAN
θ value	8.99809 (rank : 135)	NC score	0.031741 (rank : 216)
Query Neighborhood Hits	141	Target Neighborhood Hits	93	Shared Neighborhood Hits	6
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

SCN1A_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.019650 (rank : 222)
Query Neighborhood Hits	141	Target Neighborhood Hits	148	Shared Neighborhood Hits	15
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SCN2A_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.019652 (rank : 221)
Query Neighborhood Hits	141	Target Neighborhood Hits	157	Shared Neighborhood Hits	16
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN3A_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.020468 (rank : 219)
Query Neighborhood Hits	141	Target Neighborhood Hits	115	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SCN8A_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.019113 (rank : 224)
Query Neighborhood Hits	141	Target Neighborhood Hits	135	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.019190 (rank : 223)
Query Neighborhood Hits	141	Target Neighborhood Hits	136	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN9A_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.020224 (rank : 220)
Query Neighborhood Hits	141	Target Neighborhood Hits	157	Shared Neighborhood Hits	15
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

ACTN1_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.091111 (rank : 176)
Query Neighborhood Hits	141	Target Neighborhood Hits	221	Shared Neighborhood Hits	54
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN1_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.090596 (rank : 178)
Query Neighborhood Hits	141	Target Neighborhood Hits	216	Shared Neighborhood Hits	53
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN2_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.100326 (rank : 164)
Query Neighborhood Hits	141	Target Neighborhood Hits	295	Shared Neighborhood Hits	56
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN2_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.098371 (rank : 167)
Query Neighborhood Hits	141	Target Neighborhood Hits	287	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

ACTN3_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.091987 (rank : 173)
Query Neighborhood Hits	141	Target Neighborhood Hits	272	Shared Neighborhood Hits	49
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN3_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.091971 (rank : 174)
Query Neighborhood Hits	141	Target Neighborhood Hits	265	Shared Neighborhood Hits	49
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN4_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.091064 (rank : 177)
Query Neighborhood Hits	141	Target Neighborhood Hits	279	Shared Neighborhood Hits	55
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN4_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.087607 (rank : 180)
Query Neighborhood Hits	141	Target Neighborhood Hits	276	Shared Neighborhood Hits	54
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

AIF1_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.119712 (rank : 149)
Query Neighborhood Hits	141	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	P55008, Q9UKS9	Gene names	AIF1, G1, IBA1
Domain Architecture
Description	Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (Protein G1).

AIF1_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.125720 (rank : 144)
Query Neighborhood Hits	141	Target Neighborhood Hits	41	Shared Neighborhood Hits	29
SwissProt Accessions	O70200	Gene names	Aif1, Iba1
Domain Architecture	No domain graphic available
Description	Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1).

AYT1A_MOUSE
θ value	θ > 10 (rank : 152)	NC score	0.206730 (rank : 106)
Query Neighborhood Hits	141	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BYI6	Gene names	Aytl1a, Aytl1
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1-A (EC 2.3.1.-).

AYT1B_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.196365 (rank : 114)
Query Neighborhood Hits	141	Target Neighborhood Hits	113	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D5U0	Gene names	Aytl1b
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1-B (EC 2.3.1.-).

AYTL1_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.204817 (rank : 107)
Query Neighborhood Hits	141	Target Neighborhood Hits	140	Shared Neighborhood Hits	86
SwissProt Accessions	Q7L5N7, Q6MZJ6, Q9NX23	Gene names	AYTL1
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1 (EC 2.3.1.-).

CAB45_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.110443 (rank : 158)
Query Neighborhood Hits	141	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BRK5, Q8NBQ3, Q9NZP7	Gene names	SDF4, CAB45
Domain Architecture
Description	45 kDa calcium-binding protein precursor (Cab45) (Stromal cell-derived factor 4) (SDF-4).

CAB45_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.118395 (rank : 153)
Query Neighborhood Hits	141	Target Neighborhood Hits	82	Shared Neighborhood Hits	48
SwissProt Accessions	Q61112, Q61113	Gene names	Sdf4, Cab45
Domain Architecture	No domain graphic available
Description	45 kDa calcium-binding protein precursor (Cab45) (Stromal cell-derived factor 4) (SDF-4).

CALU_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.165042 (rank : 134)
Query Neighborhood Hits	141	Target Neighborhood Hits	114	Shared Neighborhood Hits	74
SwissProt Accessions	O43852, O60456, Q6FHB9, Q96RL3, Q9NR43	Gene names	CALU
Domain Architecture
Description	Calumenin precursor (Crocalbin) (IEF SSP 9302).

CALU_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.174186 (rank : 132)
Query Neighborhood Hits	141	Target Neighborhood Hits	113	Shared Neighborhood Hits	77
SwissProt Accessions	O35887	Gene names	Calu
Domain Architecture
Description	Calumenin precursor (Crocalbin).

CAN11_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.058857 (rank : 201)
Query Neighborhood Hits	141	Target Neighborhood Hits	63	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UMQ6, Q8N4R5	Gene names	CAPN11
Domain Architecture
Description	Calpain-11 (EC 3.4.22.-) (Calcium-activated neutral proteinase 11) (CANP 11).

CAN2_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.054611 (rank : 206)
Query Neighborhood Hits	141	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	O08529, O35518, O54843	Gene names	Capn2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (80 kDa M-calpain subunit) (CALP80).

CAN3_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.082844 (rank : 185)
Query Neighborhood Hits	141	Target Neighborhood Hits	96	Shared Neighborhood Hits	42
SwissProt Accessions	P20807, Q9BTU4, Q9Y5S6, Q9Y5S7	Gene names	CAPN3, CANP3, CANPL3, NCL1
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3) (nCL-1).

CAN3_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.085787 (rank : 182)
Query Neighborhood Hits	141	Target Neighborhood Hits	115	Shared Neighborhood Hits	34
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

CAN9_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.061833 (rank : 198)
Query Neighborhood Hits	141	Target Neighborhood Hits	68	Shared Neighborhood Hits	37
SwissProt Accessions	O14815, Q9NS74	Gene names	CAPN9, NCL4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4) (CG36 protein).

CAN9_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.061031 (rank : 199)
Query Neighborhood Hits	141	Target Neighborhood Hits	73	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D805, O35919	Gene names	Capn9, Ncl4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4).

CAYP1_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.317380 (rank : 70)
Query Neighborhood Hits	141	Target Neighborhood Hits	94	Shared Neighborhood Hits	74
SwissProt Accessions	Q13938, Q3MJA7, Q8WUZ3	Gene names	CAPS
Domain Architecture
Description	Calcyphosin (Calcyphosine).

CAYP2_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.093676 (rank : 170)
Query Neighborhood Hits	141	Target Neighborhood Hits	98	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BXY5, Q6PH84, Q8N242, Q8NAY5	Gene names	CAPS2
Domain Architecture
Description	Calcyphosin-2 (Calcyphosine-2).

CHP1_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.268432 (rank : 86)
Query Neighborhood Hits	141	Target Neighborhood Hits	114	Shared Neighborhood Hits	80
SwissProt Accessions	Q99653	Gene names	CHP
Domain Architecture
Description	Calcium-binding protein p22 (Calcium-binding protein CHP) (Calcineurin homologous protein) (Calcineurin B homolog).

CHP1_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.274805 (rank : 84)
Query Neighborhood Hits	141	Target Neighborhood Hits	117	Shared Neighborhood Hits	83
SwissProt Accessions	P61022, Q62877, Q6ZWQ8	Gene names	Chp, Sid470
Domain Architecture
Description	Calcium-binding protein p22 (Calcium-binding protein CHP) (Calcineurin homologous protein) (Sid 470).

CHP2_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.278191 (rank : 82)
Query Neighborhood Hits	141	Target Neighborhood Hits	122	Shared Neighborhood Hits	83
SwissProt Accessions	O43745	Gene names	CHP2, HCA520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520).

CPNS2_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.101732 (rank : 162)
Query Neighborhood Hits	141	Target Neighborhood Hits	66	Shared Neighborhood Hits	42
SwissProt Accessions	Q96L46, Q9BPV4	Gene names	CAPNS2
Domain Architecture
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

CPNS2_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.072710 (rank : 193)
Query Neighborhood Hits	141	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D7J7	Gene names	Capns2
Domain Architecture	No domain graphic available
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

DGKG_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.093005 (rank : 172)
Query Neighborhood Hits	141	Target Neighborhood Hits	171	Shared Neighborhood Hits	55
SwissProt Accessions	P49619	Gene names	DGKG, DAGK3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma).

DGKG_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.101534 (rank : 163)
Query Neighborhood Hits	141	Target Neighborhood Hits	188	Shared Neighborhood Hits	59
SwissProt Accessions	Q91WG7	Gene names	Dgkg, Dagk3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma) (88 kDa diacylglycerol kinase).

EFCB2_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.228532 (rank : 99)
Query Neighborhood Hits	141	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	Q5VUJ9, Q59G23, Q9BS36	Gene names	EFCAB2
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 2.

EFCB2_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.254710 (rank : 92)
Query Neighborhood Hits	141	Target Neighborhood Hits	64	Shared Neighborhood Hits	36
SwissProt Accessions	Q9CQ46, Q9CS07	Gene names	Efcab2
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 2.

EFCB3_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.123661 (rank : 146)
Query Neighborhood Hits	141	Target Neighborhood Hits	50	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N7B9	Gene names	EFCAB3
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 3.

EFCB3_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.129791 (rank : 142)
Query Neighborhood Hits	141	Target Neighborhood Hits	65	Shared Neighborhood Hits	38
SwissProt Accessions	Q80X60	Gene names	Efcab3
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 3.

EFHA2_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.054120 (rank : 208)
Query Neighborhood Hits	141	Target Neighborhood Hits	61	Shared Neighborhood Hits	26
SwissProt Accessions	Q86XE3, Q8IYZ3	Gene names	EFHA2
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member A2.

EFHB_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.155932 (rank : 139)
Query Neighborhood Hits	141	Target Neighborhood Hits	125	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N7U6, Q6ZWK9, Q8IV58, Q96LQ6	Gene names	EFHB
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

EFHB_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.073421 (rank : 192)
Query Neighborhood Hits	141	Target Neighborhood Hits	120	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CDU5	Gene names	Efhb
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

EFHC1_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.066861 (rank : 195)
Query Neighborhood Hits	141	Target Neighborhood Hits	61	Shared Neighborhood Hits	32
SwissProt Accessions	Q5JVL4, Q5XKM4, Q6E1U7, Q6E1U8, Q8WUL2, Q9NVW6	Gene names	EFHC1
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing protein 1.

EFHD1_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.200535 (rank : 109)
Query Neighborhood Hits	141	Target Neighborhood Hits	108	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BUP0, Q9BTF8, Q9H8I2, Q9HBQ0	Gene names	EFHD1, SWS2
Domain Architecture
Description	EF-hand domain-containing protein 1 (Swiprosin-2).

EFHD2_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.182393 (rank : 127)
Query Neighborhood Hits	141	Target Neighborhood Hits	86	Shared Neighborhood Hits	55
SwissProt Accessions	Q96C19	Gene names	EFHD2, SWS1
Domain Architecture
Description	EF-hand domain-containing protein 2 (Swiprosin-1).

EGLX_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.055734 (rank : 203)
Query Neighborhood Hits	141	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NXG6, Q6PAG6, Q8TCJ9, Q8WV55, Q96F22, Q9BW77	Gene names	PH4
Domain Architecture
Description	Putative HIF-prolyl hydroxylase PH-4 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl 4-hydroxylase).

EGLX_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.055441 (rank : 205)
Query Neighborhood Hits	141	Target Neighborhood Hits	49	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BG58, Q8CAF1, Q9D499	Gene names	Ph4
Domain Architecture
Description	Putative HIF-prolyl hydroxylase PH-4 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl 4-hydroxylase).

FKBP9_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.056158 (rank : 202)
Query Neighborhood Hits	141	Target Neighborhood Hits	72	Shared Neighborhood Hits	42
SwissProt Accessions	O95302, Q3MIR7, Q6IN76, Q6P2N1, Q96EX5, Q96IJ9	Gene names	FKBP9, FKBP60, FKBP63
Domain Architecture	No domain graphic available
Description	FK506-binding protein 9 precursor (EC 5.2.1.8) (Peptidyl-prolyl cis- trans isomerase) (PPIase) (Rotamase).

GPDM_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.194222 (rank : 117)
Query Neighborhood Hits	141	Target Neighborhood Hits	116	Shared Neighborhood Hits	64
SwissProt Accessions	P43304, Q59FR1, Q9HAP9	Gene names	GPD2
Domain Architecture
Description	Glycerol-3-phosphate dehydrogenase, mitochondrial precursor (EC 1.1.99.5) (GPD-M) (GPDH-M) (mtGPD).

GPDM_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.157816 (rank : 138)
Query Neighborhood Hits	141	Target Neighborhood Hits	101	Shared Neighborhood Hits	47
SwissProt Accessions	Q64521, Q61507	Gene names	Gpd2, Gdm1
Domain Architecture
Description	Glycerol-3-phosphate dehydrogenase, mitochondrial precursor (EC 1.1.99.5) (GPD-M) (GPDH-M).

GRAN_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.103135 (rank : 161)
Query Neighborhood Hits	141	Target Neighborhood Hits	57	Shared Neighborhood Hits	37
SwissProt Accessions	P28676	Gene names	GCA, GCL
Domain Architecture
Description	Grancalcin.

GRAN_MOUSE
θ value	θ > 10 (rank : 190)	NC score	0.083634 (rank : 184)
Query Neighborhood Hits	141	Target Neighborhood Hits	53	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VC88, Q8BL53, Q8K3Z6	Gene names	Gca
Domain Architecture	No domain graphic available
Description	Grancalcin.

IBA2_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.118514 (rank : 152)
Query Neighborhood Hits	141	Target Neighborhood Hits	45	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BQI0, Q6ZR40, Q8NAX7, Q8WU47, Q9H9G0	Gene names	IBA2, C9orf58
Domain Architecture	No domain graphic available
Description	Ionized calcium-binding adapter molecule 2.

IBA2_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.119785 (rank : 148)
Query Neighborhood Hits	141	Target Neighborhood Hits	49	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EQX4, Q8C150	Gene names	Iba2
Domain Architecture	No domain graphic available
Description	Ionized calcium-binding adapter molecule 2.

KCIP2_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.280020 (rank : 80)
Query Neighborhood Hits	141	Target Neighborhood Hits	125	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NS61, Q7Z6F1, Q96K86, Q96T41, Q96T42, Q96T43, Q96T44, Q9H0N4, Q9HD10, Q9HD11, Q9NS60, Q9NY10, Q9NZI1	Gene names	KCNIP2, KCHIP2
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Potassium channel-interacting protein 2) (Cardiac voltage-gated potassium channel modulatory subunit).

KCIP2_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.279577 (rank : 81)
Query Neighborhood Hits	141	Target Neighborhood Hits	124	Shared Neighborhood Hits	81
SwissProt Accessions	Q9JJ69, Q6DTJ2, Q8K1T8, Q8K1T9, Q8K1U0, Q8VHN4, Q8VHN5, Q8VHN6, Q9JJ68	Gene names	Kcnip2, Kchip2
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Potassium channel-interacting protein 2).

KIP1_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.267623 (rank : 89)
Query Neighborhood Hits	141	Target Neighborhood Hits	105	Shared Neighborhood Hits	78
SwissProt Accessions	Q99828, O00693, O00735, Q6IB49, Q96J54, Q99971	Gene names	CIB1, CIB, KIP, PRKDCIP
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB) (SNK- interacting protein 2-28) (SIP2-28).

KIP1_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.267994 (rank : 87)
Query Neighborhood Hits	141	Target Neighborhood Hits	109	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Z0F4, Q3TN80	Gene names	Cib1, Cib, Kip, Prkdcip
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB).

KIP3_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.227265 (rank : 100)
Query Neighborhood Hits	141	Target Neighborhood Hits	83	Shared Neighborhood Hits	62
SwissProt Accessions	Q96Q77	Gene names	CIB3, KIP3
Domain Architecture
Description	Calcium and integrin-binding protein 3 (Kinase-interacting protein 3) (KIP 3).

MLE1_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.192075 (rank : 119)
Query Neighborhood Hits	141	Target Neighborhood Hits	64	Shared Neighborhood Hits	36
SwissProt Accessions	P05976	Gene names	MYL1
Domain Architecture
Description	Myosin light chain 1, skeletal muscle isoform (MLC1F) (A1 catalytic) (Alkali myosin light chain 1).

MLE1_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.187554 (rank : 122)
Query Neighborhood Hits	141	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	P05977	Gene names	Myl1, Mylf
Domain Architecture
Description	Myosin light chain 1, skeletal muscle isoform (MLC1F) (A1 catalytic) (Alkali myosin light chain 1).

MLE3_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.190620 (rank : 121)
Query Neighborhood Hits	141	Target Neighborhood Hits	60	Shared Neighborhood Hits	34
SwissProt Accessions	P06741	Gene names	MYL1
Domain Architecture
Description	Myosin light chain 3, skeletal muscle isoform (A2 catalytic) (Alkali myosin light chain 3) (MLC3F).

MLE3_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.186065 (rank : 124)
Query Neighborhood Hits	141	Target Neighborhood Hits	66	Shared Neighborhood Hits	34
SwissProt Accessions	P05978	Gene names	Myl1, Mylf
Domain Architecture
Description	Myosin light chain 3, skeletal muscle isoform (A2 catalytic) (Alkali myosin light chain 3) (MLC3F).

MLRA_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.194474 (rank : 116)
Query Neighborhood Hits	141	Target Neighborhood Hits	91	Shared Neighborhood Hits	46
SwissProt Accessions	Q01449	Gene names	MYL7, MYLC2A
Domain Architecture
Description	Myosin regulatory light chain 2, atrial isoform (Myosin light chain 2a) (MLC-2a) (MLC2a) (Myosin regulatory light chain 7).

MLRA_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.198185 (rank : 111)
Query Neighborhood Hits	141	Target Neighborhood Hits	101	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QVP4, Q63977, Q9JIE8	Gene names	Myl7, Mylc2a
Domain Architecture
Description	Myosin regulatory light chain 2, atrial isoform (Myosin light chain 2a) (MLC-2a) (MLC2a) (Myosin regulatory light chain 7).

MLRM_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.247797 (rank : 94)
Query Neighborhood Hits	141	Target Neighborhood Hits	111	Shared Neighborhood Hits	59
SwissProt Accessions	P19105	Gene names	MRLC2, MLCB, RLC
Domain Architecture
Description	Myosin regulatory light chain 2, nonsarcomeric (Myosin RLC).

MLRN_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.255645 (rank : 91)
Query Neighborhood Hits	141	Target Neighborhood Hits	107	Shared Neighborhood Hits	60
SwissProt Accessions	P24844, Q9H136	Gene names	MYL9, MLC2, MRLC1, MYRL2
Domain Architecture
Description	Myosin regulatory light chain 2, smooth muscle isoform (Myosin RLC) (Myosin regulatory light chain 9) (LC20).

MLRN_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.252309 (rank : 93)
Query Neighborhood Hits	141	Target Neighborhood Hits	106	Shared Neighborhood Hits	58
SwissProt Accessions	Q9CQ19, Q80X77	Gene names	Myl9, Myrl2
Domain Architecture
Description	Myosin regulatory light chain 2, smooth muscle isoform (Myosin RLC) (Myosin regulatory light chain 9).

MLRS_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.185324 (rank : 125)
Query Neighborhood Hits	141	Target Neighborhood Hits	72	Shared Neighborhood Hits	41
SwissProt Accessions	P97457	Gene names	Mylpf
Domain Architecture
Description	Myosin regulatory light chain 2, skeletal muscle isoform (MLC2F).

MYL3_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.181687 (rank : 128)
Query Neighborhood Hits	141	Target Neighborhood Hits	66	Shared Neighborhood Hits	35
SwissProt Accessions	P08590, Q9NRS8	Gene names	MYL3
Domain Architecture
Description	Myosin light polypeptide 3 (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular/slow twitch myosin alkali light chain) (Cardiac myosin light chain-1) (CMLC1).

MYL3_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.186360 (rank : 123)
Query Neighborhood Hits	141	Target Neighborhood Hits	70	Shared Neighborhood Hits	35
SwissProt Accessions	P09542, Q3UIF4, Q9CQZ2	Gene names	Myl3, Mlc1v, Mylc
Domain Architecture
Description	Myosin light polypeptide 3 (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular/slow twitch myosin alkali light chain).

MYL4_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.174723 (rank : 131)
Query Neighborhood Hits	141	Target Neighborhood Hits	66	Shared Neighborhood Hits	33
SwissProt Accessions	P12829, P11783	Gene names	MYL4, MLC1
Domain Architecture
Description	Myosin light polypeptide 4 (Myosin light chain 1, embryonic muscle/atrial isoform) (Myosin light chain alkali, GT-1 isoform).

MYL4_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.174737 (rank : 130)
Query Neighborhood Hits	141	Target Neighborhood Hits	63	Shared Neighborhood Hits	34
SwissProt Accessions	P09541	Gene names	Myl4, Mlc1a, Myla
Domain Architecture
Description	Myosin light polypeptide 4 (Myosin light chain 1, atrial/fetal isoform) (MLC1A) (MLC1EMB).

MYL6_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.197800 (rank : 112)
Query Neighborhood Hits	141	Target Neighborhood Hits	68	Shared Neighborhood Hits	38
SwissProt Accessions	P60660, P16475, P24572, P24573, Q12790, Q6IAZ0, Q6IPY5	Gene names	MYL6
Domain Architecture
Description	Myosin light polypeptide 6 (Smooth muscle and nonmuscle myosin light chain alkali 6) (Myosin light chain alkali 3) (Myosin light chain 3) (MLC-3) (LC17).

MYL6_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.197800 (rank : 113)
Query Neighborhood Hits	141	Target Neighborhood Hits	68	Shared Neighborhood Hits	38
SwissProt Accessions	Q60605	Gene names	Myl6, Myln
Domain Architecture
Description	Myosin light polypeptide 6 (Smooth muscle and nonmuscle myosin light chain alkali 6) (Myosin light chain alkali 3) (Myosin light chain 3) (MLC-3) (LC17).

NUCB2_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.052025 (rank : 209)
Query Neighborhood Hits	141	Target Neighborhood Hits	321	Shared Neighborhood Hits	38
SwissProt Accessions	P80303, Q8NFT5	Gene names	NUCB2, NEFA
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA) (Gastric cancer antigen Zg4).

NUCB2_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.054426 (rank : 207)
Query Neighborhood Hits	141	Target Neighborhood Hits	459	Shared Neighborhood Hits	47
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

PCAT1_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.114405 (rank : 155)
Query Neighborhood Hits	141	Target Neighborhood Hits	80	Shared Neighborhood Hits	53
SwissProt Accessions	Q8NF37, Q1HAQ1, Q7Z4G6, Q8N3U7, Q8WUL8, Q9GZW6	Gene names	AYTL2, LPCAT1, PFAAP3
Domain Architecture	No domain graphic available
Description	1-acylglycerophosphocholine O-acyltransferase 1 (EC 2.3.1.23) (Lung- type acyl-coa:lysophosphatidylcholine acyltransferase 1) (Acyltransferase-like 2) (Phosphonoformate immuno-associated protein 3).

PCAT1_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.118615 (rank : 151)
Query Neighborhood Hits	141	Target Neighborhood Hits	78	Shared Neighborhood Hits	51
SwissProt Accessions	Q3TFD2, Q3TAX4, Q6NXZ6, Q8BG23, Q8BUX7, Q99JU6	Gene names	Aytl2, Lpcat1
Domain Architecture	No domain graphic available
Description	1-acylglycerophosphocholine O-acyltransferase 1 (EC 2.3.1.23) (Lung- type acyl-coa:lysophosphatidylcholine acyltransferase 1) (mLPCAT1) (Acyltransferase-like 2).

PPE1_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.123009 (rank : 147)
Query Neighborhood Hits	141	Target Neighborhood Hits	137	Shared Neighborhood Hits	74
SwissProt Accessions	O14829, O15253, Q9NU21, Q9UJH0	Gene names	PPEF1, PPEF, PPP7C
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 1 (EC 3.1.3.16) (PPEF-1) (Protein phosphatase with EF calcium-binding domain) (PPEF) (Serine/threonine-protein phosphatase 7) (PP7).

PPE2_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.081431 (rank : 188)
Query Neighborhood Hits	141	Target Neighborhood Hits	106	Shared Neighborhood Hits	51
SwissProt Accessions	O14830, O14831	Gene names	PPEF2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

PPE2_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.091910 (rank : 175)
Query Neighborhood Hits	141	Target Neighborhood Hits	112	Shared Neighborhood Hits	59
SwissProt Accessions	O35385	Gene names	Ppef2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

RHBD4_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.073898 (rank : 191)
Query Neighborhood Hits	141	Target Neighborhood Hits	69	Shared Neighborhood Hits	40
SwissProt Accessions	P58872	Gene names	RHBDL4, VRHO
Domain Architecture
Description	Rhomboid-related protein 4 (EC 3.4.21.105) (Ventrhoid transmembrane protein).

RHBD4_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.068096 (rank : 194)
Query Neighborhood Hits	141	Target Neighborhood Hits	61	Shared Neighborhood Hits	35
SwissProt Accessions	P58873	Gene names	Rhbdl4, Vrho
Domain Architecture
Description	Rhomboid-related protein 4 (EC 3.4.21.105) (Ventrhoid transmembrane protein).

S100G_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.088574 (rank : 179)
Query Neighborhood Hits	141	Target Neighborhood Hits	103	Shared Neighborhood Hits	48
SwissProt Accessions	P29377	Gene names	S100G, CABP9K, CALB3, S100D
Domain Architecture
Description	Protein S100-G (S100 calcium-binding protein G) (Vitamin D-dependent calcium-binding protein, intestinal) (CABP) (Calbindin D9K).

S100G_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.055629 (rank : 204)
Query Neighborhood Hits	141	Target Neighborhood Hits	87	Shared Neighborhood Hits	39
SwissProt Accessions	P97816	Gene names	S100g, Calb3, S100d
Domain Architecture
Description	Protein S100-G (S100 calcium-binding protein G) (Vitamin D-dependent calcium-binding protein, intestinal) (CABP) (Calbindin D9K).

SORCN_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.124046 (rank : 145)
Query Neighborhood Hits	141	Target Neighborhood Hits	82	Shared Neighborhood Hits	43
SwissProt Accessions	P30626	Gene names	SRI
Domain Architecture
Description	Sorcin (22 kDa protein) (CP-22) (V19).

SORCN_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.118846 (rank : 150)
Query Neighborhood Hits	141	Target Neighborhood Hits	72	Shared Neighborhood Hits	38
SwissProt Accessions	Q6P069, Q3UKC5, Q9CR38, Q9D7V8	Gene names	Sri
Domain Architecture	No domain graphic available
Description	Sorcin.

TESC_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.112780 (rank : 157)
Query Neighborhood Hits	141	Target Neighborhood Hits	64	Shared Neighborhood Hits	45
SwissProt Accessions	Q96BS2	Gene names	TESC
Domain Architecture	No domain graphic available
Description	Tescalcin (TSC).

TESC_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.096963 (rank : 168)
Query Neighborhood Hits	141	Target Neighborhood Hits	63	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JKL5	Gene names	Tesc
Domain Architecture	No domain graphic available
Description	Tescalcin (TSC).

UBP32_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.100228 (rank : 165)
Query Neighborhood Hits	141	Target Neighborhood Hits	170	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

Hits sorted by NC score

CALB2_MOUSE
NC score	0.999962 (rank : 1)	θ value	7.52544e-156 (rank : 1)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	141
SwissProt Accessions	Q08331, Q60964, Q9JM81	Gene names	Calb2
Domain Architecture
Description	Calretinin (CR).

CALB2_HUMAN
NC score	0.996682 (rank : 2)	θ value	2.04937e-153 (rank : 2)
Query Neighborhood Hits	141	Target Neighborhood Hits	149	Shared Neighborhood Hits	139
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

CALB1_MOUSE
NC score	0.948254 (rank : 3)	θ value	1.2666e-86 (rank : 4)
Query Neighborhood Hits	141	Target Neighborhood Hits	129	Shared Neighborhood Hits	97
SwissProt Accessions	P12658, Q545N6	Gene names	Calb1
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K) (Spot 35 protein) (PCD-29).

CALB1_HUMAN
NC score	0.948173 (rank : 4)	θ value	6.71607e-88 (rank : 3)
Query Neighborhood Hits	141	Target Neighborhood Hits	130	Shared Neighborhood Hits	98
SwissProt Accessions	P05937	Gene names	CALB1, CAB27
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K).

SEGN_HUMAN
NC score	0.874051 (rank : 5)	θ value	2.67181e-44 (rank : 5)
Query Neighborhood Hits	141	Target Neighborhood Hits	96	Shared Neighborhood Hits	73
SwissProt Accessions	O76038, Q5VV44, Q96QV7, Q9UJF6	Gene names	SCGN, SECRET
Domain Architecture
Description	Secretagogin.

SEGN_MOUSE
NC score	0.855200 (rank : 6)	θ value	1.51715e-39 (rank : 6)
Query Neighborhood Hits	141	Target Neighborhood Hits	101	Shared Neighborhood Hits	78
SwissProt Accessions	Q91WD9	Gene names	Scgn
Domain Architecture
Description	Secretagogin.

CALL5_HUMAN
NC score	0.492669 (rank : 7)	θ value	5.81887e-07 (rank : 10)
Query Neighborhood Hits	141	Target Neighborhood Hits	231	Shared Neighborhood Hits	120
SwissProt Accessions	Q9NZT1, Q8IXU8	Gene names	CALML5, CLSP
Domain Architecture
Description	Calmodulin-like protein 5 (Calmodulin-like skin protein).

CALM4_MOUSE
NC score	0.490339 (rank : 8)	θ value	8.40245e-06 (rank : 11)
Query Neighborhood Hits	141	Target Neighborhood Hits	229	Shared Neighborhood Hits	118
SwissProt Accessions	Q9JM83, Q9CR31, Q9D1E9	Gene names	Calm4, Dd112
Domain Architecture
Description	Calmodulin-4 (Calcium-binding protein Dd112).

TNNC2_MOUSE
NC score	0.487570 (rank : 9)	θ value	5.44631e-05 (rank : 27)
Query Neighborhood Hits	141	Target Neighborhood Hits	233	Shared Neighborhood Hits	118
SwissProt Accessions	P20801	Gene names	Tnnc2, Tncs
Domain Architecture
Description	Troponin C, skeletal muscle (STNC).

TNNC2_HUMAN
NC score	0.480947 (rank : 10)	θ value	0.00035302 (rank : 36)
Query Neighborhood Hits	141	Target Neighborhood Hits	234	Shared Neighborhood Hits	118
SwissProt Accessions	P02585	Gene names	TNNC2
Domain Architecture
Description	Troponin C, skeletal muscle.

CANB2_MOUSE
NC score	0.472365 (rank : 11)	θ value	0.00134147 (rank : 42)
Query Neighborhood Hits	141	Target Neighborhood Hits	173	Shared Neighborhood Hits	108
SwissProt Accessions	Q63811	Gene names	Ppp3r2
Domain Architecture
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform).

CALL3_HUMAN
NC score	0.471588 (rank : 12)	θ value	8.97725e-08 (rank : 9)
Query Neighborhood Hits	141	Target Neighborhood Hits	225	Shared Neighborhood Hits	113
SwissProt Accessions	P27482	Gene names	CALML3
Domain Architecture
Description	Calmodulin-like protein 3 (Calmodulin-related protein NB-1) (CaM-like protein) (CLP).

CALM_HUMAN
NC score	0.469998 (rank : 13)	θ value	4.0297e-08 (rank : 7)
Query Neighborhood Hits	141	Target Neighborhood Hits	232	Shared Neighborhood Hits	115
SwissProt Accessions	P62158, P02593, P70667, P99014, Q13942, Q53S29, Q61379, Q61380, Q96HK3	Gene names	CALM1, CALM, CAM, CAM1
Domain Architecture
Description	Calmodulin (CaM).

CALM_MOUSE
NC score	0.469998 (rank : 14)	θ value	4.0297e-08 (rank : 8)
Query Neighborhood Hits	141	Target Neighborhood Hits	232	Shared Neighborhood Hits	115
SwissProt Accessions	P62204, P02593, P70667, P99014, Q61379, Q61380	Gene names	Calm1, Calm, Cam, Cam1
Domain Architecture
Description	Calmodulin (CaM).

CANB2_HUMAN
NC score	0.464242 (rank : 15)	θ value	0.000602161 (rank : 38)
Query Neighborhood Hits	141	Target Neighborhood Hits	163	Shared Neighborhood Hits	104
SwissProt Accessions	Q96LZ3, Q7Z4V8, Q8WYJ4	Gene names	PPP3R2, CBLP
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform) (Calcineurin B-like protein) (CBLP) (CNBII).

CETN1_HUMAN
NC score	0.456943 (rank : 16)	θ value	1.87187e-05 (rank : 17)
Query Neighborhood Hits	141	Target Neighborhood Hits	232	Shared Neighborhood Hits	112
SwissProt Accessions	Q12798	Gene names	CETN1, CEN1, CETN
Domain Architecture
Description	Centrin-1 (Caltractin isoform 2).

CANB1_HUMAN
NC score	0.456209 (rank : 17)	θ value	0.00102713 (rank : 40)
Query Neighborhood Hits	141	Target Neighborhood Hits	183	Shared Neighborhood Hits	109
SwissProt Accessions	P63098, P06705, P15117, Q08044	Gene names	PPP3R1, CNA2, CNB
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB1_MOUSE
NC score	0.456125 (rank : 18)	θ value	0.00102713 (rank : 41)
Query Neighborhood Hits	141	Target Neighborhood Hits	183	Shared Neighborhood Hits	109
SwissProt Accessions	Q63810	Gene names	Ppp3r1, Cnb
Domain Architecture
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CABP1_MOUSE
NC score	0.452931 (rank : 19)	θ value	1.09739e-05 (rank : 15)
Query Neighborhood Hits	141	Target Neighborhood Hits	197	Shared Neighborhood Hits	103
SwissProt Accessions	Q9JLK7, Q9JLK6	Gene names	Cabp1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1).

CABP1_HUMAN
NC score	0.452861 (rank : 20)	θ value	1.09739e-05 (rank : 14)
Query Neighborhood Hits	141	Target Neighborhood Hits	197	Shared Neighborhood Hits	103
SwissProt Accessions	Q9NZU7, O95663, Q9NZU8	Gene names	CABP1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1) (Calbrain).

CETN2_HUMAN
NC score	0.450018 (rank : 21)	θ value	1.87187e-05 (rank : 18)
Query Neighborhood Hits	141	Target Neighborhood Hits	213	Shared Neighborhood Hits	112
SwissProt Accessions	P41208, Q53XW1	Gene names	CETN2, CALT, CEN2
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CABP4_HUMAN
NC score	0.446948 (rank : 22)	θ value	4.1701e-05 (rank : 24)
Query Neighborhood Hits	141	Target Neighborhood Hits	250	Shared Neighborhood Hits	112
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

CETN2_MOUSE
NC score	0.446839 (rank : 23)	θ value	2.44474e-05 (rank : 20)
Query Neighborhood Hits	141	Target Neighborhood Hits	211	Shared Neighborhood Hits	111
SwissProt Accessions	Q9R1K9, Q3UBB4, Q9CWM0	Gene names	Cetn2, Calt
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

CABP2_MOUSE
NC score	0.444619 (rank : 24)	θ value	5.44631e-05 (rank : 25)
Query Neighborhood Hits	141	Target Neighborhood Hits	204	Shared Neighborhood Hits	107
SwissProt Accessions	Q9JLK4, Q9JLK5	Gene names	Cabp2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CETN1_MOUSE
NC score	0.443757 (rank : 25)	θ value	2.44474e-05 (rank : 19)
Query Neighborhood Hits	141	Target Neighborhood Hits	231	Shared Neighborhood Hits	111
SwissProt Accessions	P41209, Q3V119, Q9D9G9, Q9DAL6	Gene names	Cetn1, Calt
Domain Architecture
Description	Centrin-1 (Caltractin).

TNNC1_MOUSE
NC score	0.442599 (rank : 26)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	141	Target Neighborhood Hits	221	Shared Neighborhood Hits	118
SwissProt Accessions	P19123	Gene names	Tnnc1, Tncc
Domain Architecture
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

GUC1A_MOUSE
NC score	0.442280 (rank : 27)	θ value	0.000121331 (rank : 29)
Query Neighborhood Hits	141	Target Neighborhood Hits	152	Shared Neighborhood Hits	101
SwissProt Accessions	P43081	Gene names	Guca1a, Gcap, Gcap1, Guca1
Domain Architecture
Description	Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A).

CABP2_HUMAN
NC score	0.439944 (rank : 28)	θ value	9.29e-05 (rank : 28)
Query Neighborhood Hits	141	Target Neighborhood Hits	205	Shared Neighborhood Hits	105
SwissProt Accessions	Q9NPB3	Gene names	CABP2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

TNNC1_HUMAN
NC score	0.439485 (rank : 29)	θ value	1.81305 (rank : 109)
Query Neighborhood Hits	141	Target Neighborhood Hits	219	Shared Neighborhood Hits	118
SwissProt Accessions	P63316, O14800, P02590, P04463	Gene names	TNNC1, TNNC
Domain Architecture	No domain graphic available
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

GUC1A_HUMAN
NC score	0.436961 (rank : 30)	θ value	0.000158464 (rank : 31)
Query Neighborhood Hits	141	Target Neighborhood Hits	147	Shared Neighborhood Hits	100
SwissProt Accessions	P43080, Q9NU14	Gene names	GUCA1A, GCAP, GCAP1, GUCA1
Domain Architecture
Description	Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A).

CABP4_MOUSE
NC score	0.430704 (rank : 31)	θ value	0.000786445 (rank : 39)
Query Neighborhood Hits	141	Target Neighborhood Hits	212	Shared Neighborhood Hits	107
SwissProt Accessions	Q8VHC5	Gene names	Cabp4
Domain Architecture	No domain graphic available
Description	Calcium-binding protein 4 (CaBP4).

CETN3_MOUSE
NC score	0.430039 (rank : 32)	θ value	0.00509761 (rank : 47)
Query Neighborhood Hits	141	Target Neighborhood Hits	208	Shared Neighborhood Hits	114
SwissProt Accessions	O35648	Gene names	Cetn3, Cen3
Domain Architecture
Description	Centrin-3.

CETN3_HUMAN
NC score	0.429534 (rank : 33)	θ value	0.00509761 (rank : 46)
Query Neighborhood Hits	141	Target Neighborhood Hits	211	Shared Neighborhood Hits	114
SwissProt Accessions	O15182, Q9BS23	Gene names	CETN3, CEN3
Domain Architecture
Description	Centrin-3.

CABP5_HUMAN
NC score	0.422387 (rank : 34)	θ value	0.00298849 (rank : 43)
Query Neighborhood Hits	141	Target Neighborhood Hits	197	Shared Neighborhood Hits	110
SwissProt Accessions	Q9NP86	Gene names	CABP5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

PRVA_MOUSE
NC score	0.414257 (rank : 35)	θ value	0.00869519 (rank : 49)
Query Neighborhood Hits	141	Target Neighborhood Hits	77	Shared Neighborhood Hits	61
SwissProt Accessions	P32848	Gene names	Pvalb, Pva
Domain Architecture
Description	Parvalbumin alpha.

CABP5_MOUSE
NC score	0.413271 (rank : 36)	θ value	0.0113563 (rank : 51)
Query Neighborhood Hits	141	Target Neighborhood Hits	207	Shared Neighborhood Hits	114
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

GUC1C_HUMAN
NC score	0.412171 (rank : 37)	θ value	0.279714 (rank : 76)
Query Neighborhood Hits	141	Target Neighborhood Hits	148	Shared Neighborhood Hits	96
SwissProt Accessions	O95843, O95844, Q9UNM0	Gene names	GUCA1C, GCAP3
Domain Architecture
Description	Guanylyl cyclase-activating protein 3 (GCAP 3) (Guanylate cyclase activator 1C).

NCALD_HUMAN
NC score	0.406293 (rank : 38)	θ value	0.00020696 (rank : 34)
Query Neighborhood Hits	141	Target Neighborhood Hits	153	Shared Neighborhood Hits	102
SwissProt Accessions	P61601, P29554, Q8IYC3, Q9H0W2	Gene names	NCALD
Domain Architecture
Description	Neurocalcin delta.

NCALD_MOUSE
NC score	0.406293 (rank : 39)	θ value	0.00020696 (rank : 35)
Query Neighborhood Hits	141	Target Neighborhood Hits	153	Shared Neighborhood Hits	102
SwissProt Accessions	Q91X97, Q3TJS9, Q8BZN9	Gene names	Ncald, D15Ertd412e
Domain Architecture
Description	Neurocalcin delta.

CABP7_HUMAN
NC score	0.406046 (rank : 40)	θ value	0.21417 (rank : 72)
Query Neighborhood Hits	141	Target Neighborhood Hits	205	Shared Neighborhood Hits	110
SwissProt Accessions	Q86V35	Gene names	CABP7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CABP7_MOUSE
NC score	0.406046 (rank : 41)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	141	Target Neighborhood Hits	205	Shared Neighborhood Hits	110
SwissProt Accessions	Q91ZM8	Gene names	Cabp7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

HPCA_HUMAN
NC score	0.405657 (rank : 42)	θ value	8.40245e-06 (rank : 12)
Query Neighborhood Hits	141	Target Neighborhood Hits	156	Shared Neighborhood Hits	103
SwissProt Accessions	P84074, P32076, P41211, P70510	Gene names	HPCA, BDR2
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin (Calcium-binding protein BDR-2).

HPCA_MOUSE
NC score	0.405657 (rank : 43)	θ value	8.40245e-06 (rank : 13)
Query Neighborhood Hits	141	Target Neighborhood Hits	156	Shared Neighborhood Hits	103
SwissProt Accessions	P84075, P32076, P41211, P70510	Gene names	Hpca
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin.

HPCL1_MOUSE
NC score	0.405513 (rank : 44)	θ value	0.000121331 (rank : 30)
Query Neighborhood Hits	141	Target Neighborhood Hits	149	Shared Neighborhood Hits	103
SwissProt Accessions	P62748, P35333	Gene names	Hpcal1
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Neural visinin-like protein 3) (NVL-3) (NVP-3).

HPCL1_HUMAN
NC score	0.405428 (rank : 45)	θ value	0.000158464 (rank : 32)
Query Neighborhood Hits	141	Target Neighborhood Hits	150	Shared Neighborhood Hits	101
SwissProt Accessions	P37235, Q969S5	Gene names	HPCAL1, BDR1
Domain Architecture
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Calcium-binding protein BDR-1) (HLP2).

GUC1B_HUMAN
NC score	0.405131 (rank : 46)	θ value	0.000461057 (rank : 37)
Query Neighborhood Hits	141	Target Neighborhood Hits	124	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UMX6, Q9NU15	Gene names	GUCA1B, GCAP2
Domain Architecture
Description	Guanylyl cyclase-activating protein 2 (GCAP 2) (Guanylate cyclase activator 1B).

ONCO_MOUSE
NC score	0.396394 (rank : 47)	θ value	0.0148317 (rank : 53)
Query Neighborhood Hits	141	Target Neighborhood Hits	98	Shared Neighborhood Hits	72
SwissProt Accessions	P51879, Q62004	Gene names	Ocm
Domain Architecture
Description	Oncomodulin (OM) (Parvalbumin beta).

ONCO_HUMAN
NC score	0.395782 (rank : 48)	θ value	0.00509761 (rank : 48)
Query Neighborhood Hits	141	Target Neighborhood Hits	88	Shared Neighborhood Hits	66
SwissProt Accessions	P32930	Gene names	OCM, OCMN
Domain Architecture
Description	Oncomodulin (OM) (Parvalbumin beta).

CABP3_HUMAN
NC score	0.384359 (rank : 49)	θ value	1.38821 (rank : 100)
Query Neighborhood Hits	141	Target Neighborhood Hits	162	Shared Neighborhood Hits	94
SwissProt Accessions	Q9NZU6, Q9NYY0, Q9NZT9	Gene names	CABP3
Domain Architecture
Description	Calcium-binding protein 3 (CaBP3).

NCS1_HUMAN
NC score	0.382750 (rank : 50)	θ value	3.19293e-05 (rank : 22)
Query Neighborhood Hits	141	Target Neighborhood Hits	132	Shared Neighborhood Hits	97
SwissProt Accessions	P62166, P36610, Q9UK26	Gene names	FREQ, FLUP, NCS1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) (Frequenin-like protein) (Frequenin-like ubiquitous protein).

NCS1_MOUSE
NC score	0.382750 (rank : 51)	θ value	3.19293e-05 (rank : 23)
Query Neighborhood Hits	141	Target Neighborhood Hits	132	Shared Neighborhood Hits	97
SwissProt Accessions	Q8BNY6	Gene names	Freq, Ncs1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog).

PRVA_HUMAN
NC score	0.382197 (rank : 52)	θ value	0.0736092 (rank : 68)
Query Neighborhood Hits	141	Target Neighborhood Hits	63	Shared Neighborhood Hits	55
SwissProt Accessions	P20472, P78378, Q4VB78, Q5R3Q9	Gene names	PVALB
Domain Architecture	No domain graphic available
Description	Parvalbumin alpha.

GUC1B_MOUSE
NC score	0.377179 (rank : 53)	θ value	0.0252991 (rank : 58)
Query Neighborhood Hits	141	Target Neighborhood Hits	116	Shared Neighborhood Hits	81
SwissProt Accessions	Q8VBV8	Gene names	Guca1b
Domain Architecture	No domain graphic available
Description	Guanylyl cyclase-activating protein 2 (GCAP 2) (Guanylate cyclase activator 1B).

EFCB1_MOUSE
NC score	0.370095 (rank : 54)	θ value	1.06291 (rank : 97)
Query Neighborhood Hits	141	Target Neighborhood Hits	126	Shared Neighborhood Hits	87
SwissProt Accessions	Q9D3N2, Q8BSW3, Q8C982, Q8CAI0, Q9D527, Q9D5E7	Gene names	Efcab1
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 1.

CALL6_HUMAN
NC score	0.367813 (rank : 55)	θ value	0.47712 (rank : 86)
Query Neighborhood Hits	141	Target Neighborhood Hits	157	Shared Neighborhood Hits	89
SwissProt Accessions	Q8TD86, Q6Q2C4	Gene names	CALML6, CAGLP, CALGP
Domain Architecture	No domain graphic available
Description	Calmodulin-like protein 6 (Calglandulin-like protein).

PLSI_HUMAN
NC score	0.367513 (rank : 56)	θ value	2.44474e-05 (rank : 21)
Query Neighborhood Hits	141	Target Neighborhood Hits	209	Shared Neighborhood Hits	96
SwissProt Accessions	Q14651	Gene names	PLS1
Domain Architecture
Description	Plastin-1 (I-plastin) (Intestine-specific plastin).

EFCB1_HUMAN
NC score	0.357996 (rank : 57)	θ value	1.81305 (rank : 107)
Query Neighborhood Hits	141	Target Neighborhood Hits	121	Shared Neighborhood Hits	86
SwissProt Accessions	Q9HAE3	Gene names	EFCAB1
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 1.

CALN1_HUMAN
NC score	0.356580 (rank : 58)	θ value	1.81305 (rank : 104)
Query Neighborhood Hits	141	Target Neighborhood Hits	161	Shared Neighborhood Hits	91
SwissProt Accessions	Q9BXU9	Gene names	CALN1, CABP8
Domain Architecture
Description	Calneuron-1 (Calcium-binding protein CaBP8).

CALN1_MOUSE
NC score	0.356046 (rank : 59)	θ value	1.81305 (rank : 105)
Query Neighborhood Hits	141	Target Neighborhood Hits	161	Shared Neighborhood Hits	91
SwissProt Accessions	Q9JJG7	Gene names	Caln1
Domain Architecture
Description	Calneuron-1.

PDCD6_MOUSE
NC score	0.342458 (rank : 60)	θ value	0.00298849 (rank : 44)
Query Neighborhood Hits	141	Target Neighborhood Hits	142	Shared Neighborhood Hits	96
SwissProt Accessions	P12815, Q545I0, Q61145	Gene names	Pdcd6, Alg2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2) (PMP41) (ALG-257).

PDCD6_HUMAN
NC score	0.337968 (rank : 61)	θ value	0.0148317 (rank : 54)
Query Neighborhood Hits	141	Target Neighborhood Hits	141	Shared Neighborhood Hits	96
SwissProt Accessions	O75340	Gene names	PDCD6, ALG2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2).

RECO_MOUSE
NC score	0.335685 (rank : 62)	θ value	0.0193708 (rank : 57)
Query Neighborhood Hits	141	Target Neighborhood Hits	108	Shared Neighborhood Hits	73
SwissProt Accessions	P34057	Gene names	Rcvrn, Rcv1
Domain Architecture
Description	Recoverin (Cancer-associated retinopathy protein) (Protein CAR) (23 kDa photoreceptor cell-specific protein).

HPCL4_MOUSE
NC score	0.332534 (rank : 63)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	141	Target Neighborhood Hits	123	Shared Neighborhood Hits	87
SwissProt Accessions	Q8BGZ1	Gene names	Hpcal4
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 4 (Neural visinin-like protein 2) (NVP-2).

HPCL4_HUMAN
NC score	0.332484 (rank : 64)	θ value	0.279714 (rank : 77)
Query Neighborhood Hits	141	Target Neighborhood Hits	123	Shared Neighborhood Hits	87
SwissProt Accessions	Q9UM19, Q5TG97, Q8N611	Gene names	HPCAL4
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 4 (HLP4).

PLSL_MOUSE
NC score	0.326793 (rank : 65)	θ value	1.09739e-05 (rank : 16)
Query Neighborhood Hits	141	Target Neighborhood Hits	170	Shared Neighborhood Hits	81
SwissProt Accessions	Q61233, Q3UE24, Q8R1X3, Q9CV77	Gene names	Lcp1, Pls2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (pp65).

VISL1_HUMAN
NC score	0.326028 (rank : 66)	θ value	0.279714 (rank : 79)
Query Neighborhood Hits	141	Target Neighborhood Hits	124	Shared Neighborhood Hits	87
SwissProt Accessions	P62760, P28677, P29103, P42323, Q9UM20	Gene names	VSNL1, VISL1
Domain Architecture	No domain graphic available
Description	Visinin-like protein 1 (VILIP) (Hippocalcin-like protein 3) (HLP3).

VISL1_MOUSE
NC score	0.326028 (rank : 67)	θ value	0.279714 (rank : 80)
Query Neighborhood Hits	141	Target Neighborhood Hits	124	Shared Neighborhood Hits	87
SwissProt Accessions	P62761, P28677, P29103, P42323, Q9UM20	Gene names	Vsnl1, Visl1
Domain Architecture	No domain graphic available
Description	Visinin-like protein 1 (VILIP) (Neural visinin-like protein 1) (NVL-1) (NVP-1).

RECO_HUMAN
NC score	0.323965 (rank : 68)	θ value	0.125558 (rank : 70)
Query Neighborhood Hits	141	Target Neighborhood Hits	101	Shared Neighborhood Hits	66
SwissProt Accessions	P35243	Gene names	RCVRN, RCV1
Domain Architecture
Description	Recoverin (Cancer-associated retinopathy protein) (Protein CAR).

PLSL_HUMAN
NC score	0.318531 (rank : 69)	θ value	5.44631e-05 (rank : 26)
Query Neighborhood Hits	141	Target Neighborhood Hits	168	Shared Neighborhood Hits	82
SwissProt Accessions	P13796	Gene names	LCP1, PLS2
Domain Architecture
Description	Plastin-2 (L-plastin) (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P).

CAYP1_HUMAN
NC score	0.317380 (rank : 70)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	141	Target Neighborhood Hits	94	Shared Neighborhood Hits	74
SwissProt Accessions	Q13938, Q3MJA7, Q8WUZ3	Gene names	CAPS
Domain Architecture
Description	Calcyphosin (Calcyphosine).

KCIP4_MOUSE
NC score	0.314731 (rank : 71)	θ value	0.125558 (rank : 69)
Query Neighborhood Hits	141	Target Neighborhood Hits	136	Shared Neighborhood Hits	88
SwissProt Accessions	Q6PHZ8, Q6DTJ3, Q8CAD0, Q8R4I2, Q9EQ01	Gene names	Kcnip4, Calp, Kchip4
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Potassium channel-interacting protein 4) (Calsenilin-like protein).

KCIP4_HUMAN
NC score	0.311120 (rank : 72)	θ value	0.365318 (rank : 82)
Query Neighborhood Hits	141	Target Neighborhood Hits	136	Shared Neighborhood Hits	88
SwissProt Accessions	Q6PIL6, Q4W5G8, Q8NEU0, Q9BWT2, Q9H294, Q9H2A4	Gene names	KCNIP4, CALP, KCHIP4
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Potassium channel-interacting protein 4) (Calsenilin-like protein).

CSEN_HUMAN
NC score	0.308040 (rank : 73)	θ value	1.38821 (rank : 101)
Query Neighborhood Hits	141	Target Neighborhood Hits	128	Shared Neighborhood Hits	87
SwissProt Accessions	Q9Y2W7, Q53TJ5, Q96T40, Q9UJ84, Q9UJ85	Gene names	KCNIP3, CSEN, DREAM, KCHIP3
Domain Architecture
Description	Calsenilin (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3) (A-type potassium channel modulatory protein 3).

CHP2_MOUSE
NC score	0.295534 (rank : 74)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	141	Target Neighborhood Hits	122	Shared Neighborhood Hits	87
SwissProt Accessions	Q9D869	Gene names	Chp2, Hca520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520 homolog).

KCIP1_HUMAN
NC score	0.294540 (rank : 75)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	141	Target Neighborhood Hits	113	Shared Neighborhood Hits	75
SwissProt Accessions	Q9NZI2, Q5U822	Gene names	KCNIP1, KCHIP1, VABP
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1) (Vesicle APC-binding protein).

KCIP1_MOUSE
NC score	0.294235 (rank : 76)	θ value	0.813845 (rank : 92)
Query Neighborhood Hits	141	Target Neighborhood Hits	113	Shared Neighborhood Hits	75
SwissProt Accessions	Q9JJ57, Q5SSA3, Q6DTJ1, Q8BGJ4, Q8C4K4, Q8CGL1, Q8K1U1, Q8K3M2	Gene names	Kcnip1, Kchip1
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1).

KIP2_HUMAN
NC score	0.292119 (rank : 77)	θ value	0.47712 (rank : 87)
Query Neighborhood Hits	141	Target Neighborhood Hits	107	Shared Neighborhood Hits	78
SwissProt Accessions	O75838	Gene names	CIB2, KIP2
Domain Architecture	No domain graphic available
Description	Calcium and integrin-binding protein 2 (Kinase-interacting protein 2) (KIP 2).

KIP2_MOUSE
NC score	0.287123 (rank : 78)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	141	Target Neighborhood Hits	110	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Z309	Gene names	Cib2, Kip2
Domain Architecture	No domain graphic available
Description	Calcium and integrin-binding protein 2 (Kinase-interacting protein 2) (KIP 2).

CSEN_MOUSE
NC score	0.286252 (rank : 79)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	141	Target Neighborhood Hits	117	Shared Neighborhood Hits	82
SwissProt Accessions	Q9QXT8, Q924L0, Q99PH9, Q99PI0, Q99PI2, Q99PI3, Q9JHZ5	Gene names	Kcnip3, Csen, Dream, Kchip3
Domain Architecture
Description	Calsenilin (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (A-type potassium channel modulatory protein 3) (KChIP3).

KCIP2_HUMAN
NC score	0.280020 (rank : 80)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	141	Target Neighborhood Hits	125	Shared Neighborhood Hits	82
SwissProt Accessions	Q9NS61, Q7Z6F1, Q96K86, Q96T41, Q96T42, Q96T43, Q96T44, Q9H0N4, Q9HD10, Q9HD11, Q9NS60, Q9NY10, Q9NZI1	Gene names	KCNIP2, KCHIP2
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Potassium channel-interacting protein 2) (Cardiac voltage-gated potassium channel modulatory subunit).

KCIP2_MOUSE
NC score	0.279577 (rank : 81)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	141	Target Neighborhood Hits	124	Shared Neighborhood Hits	81
SwissProt Accessions	Q9JJ69, Q6DTJ2, Q8K1T8, Q8K1T9, Q8K1U0, Q8VHN4, Q8VHN5, Q8VHN6, Q9JJ68	Gene names	Kcnip2, Kchip2
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Potassium channel-interacting protein 2).

CHP2_HUMAN
NC score	0.278191 (rank : 82)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	141	Target Neighborhood Hits	122	Shared Neighborhood Hits	83
SwissProt Accessions	O43745	Gene names	CHP2, HCA520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520).

MLR5_HUMAN
NC score	0.277922 (rank : 83)	θ value	0.00390308 (rank : 45)
Query Neighborhood Hits	141	Target Neighborhood Hits	90	Shared Neighborhood Hits	55
SwissProt Accessions	Q02045	Gene names	MYL5
Domain Architecture
Description	Superfast myosin regulatory light chain 2 (MyLC-2) (MYLC2) (Myosin regulatory light chain 5).

CHP1_MOUSE
NC score	0.274805 (rank : 84)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	141	Target Neighborhood Hits	117	Shared Neighborhood Hits	83
SwissProt Accessions	P61022, Q62877, Q6ZWQ8	Gene names	Chp, Sid470
Domain Architecture
Description	Calcium-binding protein p22 (Calcium-binding protein CHP) (Calcineurin homologous protein) (Sid 470).

PLST_HUMAN
NC score	0.269267 (rank : 85)	θ value	0.0563607 (rank : 63)
Query Neighborhood Hits	141	Target Neighborhood Hits	161	Shared Neighborhood Hits	83
SwissProt Accessions	P13797, Q86YI6	Gene names	PLS3
Domain Architecture
Description	Plastin-3 (T-plastin).

CHP1_HUMAN
NC score	0.268432 (rank : 86)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	141	Target Neighborhood Hits	114	Shared Neighborhood Hits	80
SwissProt Accessions	Q99653	Gene names	CHP
Domain Architecture
Description	Calcium-binding protein p22 (Calcium-binding protein CHP) (Calcineurin homologous protein) (Calcineurin B homolog).

KIP1_MOUSE
NC score	0.267994 (rank : 87)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	141	Target Neighborhood Hits	109	Shared Neighborhood Hits	82
SwissProt Accessions	Q9Z0F4, Q3TN80	Gene names	Cib1, Cib, Kip, Prkdcip
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB).

PLST_MOUSE
NC score	0.267797 (rank : 88)	θ value	0.0563607 (rank : 64)
Query Neighborhood Hits	141	Target Neighborhood Hits	156	Shared Neighborhood Hits	78
SwissProt Accessions	Q99K51	Gene names	Pls3
Domain Architecture	No domain graphic available
Description	Plastin-3 (T-plastin).

KIP1_HUMAN
NC score	0.267623 (rank : 89)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	141	Target Neighborhood Hits	105	Shared Neighborhood Hits	78
SwissProt Accessions	Q99828, O00693, O00735, Q6IB49, Q96J54, Q99971	Gene names	CIB1, CIB, KIP, PRKDCIP
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB) (SNK- interacting protein 2-28) (SIP2-28).

RCN2_MOUSE
NC score	0.267155 (rank : 90)	θ value	0.0148317 (rank : 56)
Query Neighborhood Hits	141	Target Neighborhood Hits	108	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BP92, O70341	Gene names	Rcn2
Domain Architecture	No domain graphic available
Description	Reticulocalbin-2 precursor (Taipoxin-associated calcium-binding protein 49) (TCBP-49).

MLRN_HUMAN
NC score	0.255645 (rank : 91)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	141	Target Neighborhood Hits	107	Shared Neighborhood Hits	60
SwissProt Accessions	P24844, Q9H136	Gene names	MYL9, MLC2, MRLC1, MYRL2
Domain Architecture
Description	Myosin regulatory light chain 2, smooth muscle isoform (Myosin RLC) (Myosin regulatory light chain 9) (LC20).

EFCB2_MOUSE
NC score	0.254710 (rank : 92)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	141	Target Neighborhood Hits	64	Shared Neighborhood Hits	36
SwissProt Accessions	Q9CQ46, Q9CS07	Gene names	Efcab2
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 2.

MLRN_MOUSE
NC score	0.252309 (rank : 93)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	141	Target Neighborhood Hits	106	Shared Neighborhood Hits	58
SwissProt Accessions	Q9CQ19, Q80X77	Gene names	Myl9, Myrl2
Domain Architecture
Description	Myosin regulatory light chain 2, smooth muscle isoform (Myosin RLC) (Myosin regulatory light chain 9).

MLRM_HUMAN
NC score	0.247797 (rank : 94)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	141	Target Neighborhood Hits	111	Shared Neighborhood Hits	59
SwissProt Accessions	P19105	Gene names	MRLC2, MLCB, RLC
Domain Architecture
Description	Myosin regulatory light chain 2, nonsarcomeric (Myosin RLC).

MLRV_MOUSE
NC score	0.239937 (rank : 95)	θ value	0.47712 (rank : 88)
Query Neighborhood Hits	141	Target Neighborhood Hits	89	Shared Neighborhood Hits	56
SwissProt Accessions	P51667	Gene names	Myl2, Mylpc
Domain Architecture
Description	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v).

MLRV_HUMAN
NC score	0.235788 (rank : 96)	θ value	1.06291 (rank : 99)
Query Neighborhood Hits	141	Target Neighborhood Hits	89	Shared Neighborhood Hits	55
SwissProt Accessions	P10916, Q16123	Gene names	MYL2
Domain Architecture
Description	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v).

RCN2_HUMAN
NC score	0.234811 (rank : 97)	θ value	0.0563607 (rank : 65)
Query Neighborhood Hits	141	Target Neighborhood Hits	95	Shared Neighborhood Hits	72
SwissProt Accessions	Q14257	Gene names	RCN2, ERC55
Domain Architecture
Description	Reticulocalbin-2 precursor (Calcium-binding protein ERC-55) (E6- binding protein) (E6BP).

EFHD1_MOUSE
NC score	0.232659 (rank : 98)	θ value	1.81305 (rank : 108)
Query Neighborhood Hits	141	Target Neighborhood Hits	108	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D4J1, Q543U4	Gene names	Efhd1, Sws2
Domain Architecture
Description	EF-hand domain-containing protein 1 (Swiprosin-2).

EFCB2_HUMAN
NC score	0.228532 (rank : 99)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	141	Target Neighborhood Hits	73	Shared Neighborhood Hits	37
SwissProt Accessions	Q5VUJ9, Q59G23, Q9BS36	Gene names	EFCAB2
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 2.

KIP3_HUMAN
NC score	0.227265 (rank : 100)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	141	Target Neighborhood Hits	83	Shared Neighborhood Hits	62
SwissProt Accessions	Q96Q77	Gene names	CIB3, KIP3
Domain Architecture
Description	Calcium and integrin-binding protein 3 (Kinase-interacting protein 3) (KIP 3).

RCN3_MOUSE
NC score	0.225374 (rank : 101)	θ value	0.000158464 (rank : 33)
Query Neighborhood Hits	141	Target Neighborhood Hits	91	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BH97, Q58E50, Q8R137, Q99K35, Q9CTD4	Gene names	Rcn3, D7Ertd671e
Domain Architecture	No domain graphic available
Description	Reticulocalbin-3 precursor.

MYL6B_HUMAN
NC score	0.215189 (rank : 102)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	141	Target Neighborhood Hits	78	Shared Neighborhood Hits	44
SwissProt Accessions	P14649	Gene names	MYL6B, MLC1SA
Domain Architecture
Description	Myosin light polypeptide 6B (Smooth muscle and nonmuscle myosin light chain alkali 6B) (Myosin light chain 1 slow-twitch muscle A isoform) (MLC1sa).

RCN3_HUMAN
NC score	0.214130 (rank : 103)	θ value	0.00869519 (rank : 50)
Query Neighborhood Hits	141	Target Neighborhood Hits	89	Shared Neighborhood Hits	64
SwissProt Accessions	Q96D15, Q9HBZ8	Gene names	RCN3
Domain Architecture
Description	Reticulocalbin-3 precursor (EF-hand calcium-binding protein RLP49).

PEF1_MOUSE
NC score	0.214039 (rank : 104)	θ value	0.0252991 (rank : 59)
Query Neighborhood Hits	141	Target Neighborhood Hits	112	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BFY6, Q8VCT5, Q9CYW8, Q9D934	Gene names	Pef1
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

MYL6B_MOUSE
NC score	0.209767 (rank : 105)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	141	Target Neighborhood Hits	68	Shared Neighborhood Hits	39
SwissProt Accessions	Q8CI43	Gene names	Myl6b
Domain Architecture	No domain graphic available
Description	Myosin light polypeptide 6B (Smooth muscle and nonmuscle myosin light chain alkali 6B).

AYT1A_MOUSE
NC score	0.206730 (rank : 106)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	141	Target Neighborhood Hits	126	Shared Neighborhood Hits	82
SwissProt Accessions	Q8BYI6	Gene names	Aytl1a, Aytl1
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1-A (EC 2.3.1.-).

AYTL1_HUMAN
NC score	0.204817 (rank : 107)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	141	Target Neighborhood Hits	140	Shared Neighborhood Hits	86
SwissProt Accessions	Q7L5N7, Q6MZJ6, Q9NX23	Gene names	AYTL1
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1 (EC 2.3.1.-).

DUOX1_HUMAN
NC score	0.202844 (rank : 108)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	141	Target Neighborhood Hits	172	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NRD9, Q6ZMB3, Q6ZR09, Q9NZC1	Gene names	DUOX1, DUOX, LNOX1, THOX1
Domain Architecture	No domain graphic available
Description	Dual oxidase 1 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH thyroid oxidase 1) (Thyroid oxidase 1) (Large NOX 1) (Long NOX 1).

EFHD1_HUMAN
NC score	0.200535 (rank : 109)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	141	Target Neighborhood Hits	108	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BUP0, Q9BTF8, Q9H8I2, Q9HBQ0	Gene names	EFHD1, SWS2
Domain Architecture
Description	EF-hand domain-containing protein 1 (Swiprosin-2).

DUOX2_HUMAN
NC score	0.199581 (rank : 110)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	141	Target Neighborhood Hits	139	Shared Neighborhood Hits	78
SwissProt Accessions	Q9NRD8, Q9NR02, Q9UHF9	Gene names	DUOX2, LNOX2, THOX2
Domain Architecture	No domain graphic available
Description	Dual oxidase 2 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH oxidase/peroxidase DUOX2) (NADPH thyroid oxidase 2) (Thyroid oxidase 2) (NADH/NADPH thyroid oxidase p138-tox) (p138 thyroid oxidase) (Large NOX 2) (Long NOX 2).

MLRA_MOUSE
NC score	0.198185 (rank : 111)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	141	Target Neighborhood Hits	101	Shared Neighborhood Hits	54
SwissProt Accessions	Q9QVP4, Q63977, Q9JIE8	Gene names	Myl7, Mylc2a
Domain Architecture
Description	Myosin regulatory light chain 2, atrial isoform (Myosin light chain 2a) (MLC-2a) (MLC2a) (Myosin regulatory light chain 7).

MYL6_HUMAN
NC score	0.197800 (rank : 112)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	141	Target Neighborhood Hits	68	Shared Neighborhood Hits	38
SwissProt Accessions	P60660, P16475, P24572, P24573, Q12790, Q6IAZ0, Q6IPY5	Gene names	MYL6
Domain Architecture
Description	Myosin light polypeptide 6 (Smooth muscle and nonmuscle myosin light chain alkali 6) (Myosin light chain alkali 3) (Myosin light chain 3) (MLC-3) (LC17).

MYL6_MOUSE
NC score	0.197800 (rank : 113)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	141	Target Neighborhood Hits	68	Shared Neighborhood Hits	38
SwissProt Accessions	Q60605	Gene names	Myl6, Myln
Domain Architecture
Description	Myosin light polypeptide 6 (Smooth muscle and nonmuscle myosin light chain alkali 6) (Myosin light chain alkali 3) (Myosin light chain 3) (MLC-3) (LC17).

AYT1B_MOUSE
NC score	0.196365 (rank : 114)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	141	Target Neighborhood Hits	113	Shared Neighborhood Hits	70
SwissProt Accessions	Q9D5U0	Gene names	Aytl1b
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1-B (EC 2.3.1.-).

DJBP_MOUSE
NC score	0.195188 (rank : 115)	θ value	0.0563607 (rank : 62)
Query Neighborhood Hits	141	Target Neighborhood Hits	152	Shared Neighborhood Hits	65
SwissProt Accessions	Q6P1E8, Q5DTV8, Q6PGK8, Q9D2D8	Gene names	Djbp, Kiaa1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein.

MLRA_HUMAN
NC score	0.194474 (rank : 116)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	141	Target Neighborhood Hits	91	Shared Neighborhood Hits	46
SwissProt Accessions	Q01449	Gene names	MYL7, MYLC2A
Domain Architecture
Description	Myosin regulatory light chain 2, atrial isoform (Myosin light chain 2a) (MLC-2a) (MLC2a) (Myosin regulatory light chain 7).

GPDM_HUMAN
NC score	0.194222 (rank : 117)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	141	Target Neighborhood Hits	116	Shared Neighborhood Hits	64
SwissProt Accessions	P43304, Q59FR1, Q9HAP9	Gene names	GPD2
Domain Architecture
Description	Glycerol-3-phosphate dehydrogenase, mitochondrial precursor (EC 1.1.99.5) (GPD-M) (GPDH-M) (mtGPD).

EFHD2_MOUSE
NC score	0.193912 (rank : 118)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	141	Target Neighborhood Hits	88	Shared Neighborhood Hits	55
SwissProt Accessions	Q9D8Y0, Q9D0P4	Gene names	Efhd2, Sws1
Domain Architecture
Description	EF-hand domain-containing protein 2 (Swiprosin-1).

MLE1_HUMAN
NC score	0.192075 (rank : 119)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	141	Target Neighborhood Hits	64	Shared Neighborhood Hits	36
SwissProt Accessions	P05976	Gene names	MYL1
Domain Architecture
Description	Myosin light chain 1, skeletal muscle isoform (MLC1F) (A1 catalytic) (Alkali myosin light chain 1).

DGKB_HUMAN
NC score	0.191659 (rank : 120)	θ value	0.0736092 (rank : 67)
Query Neighborhood Hits	141	Target Neighborhood Hits	238	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

MLE3_HUMAN
NC score	0.190620 (rank : 121)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	141	Target Neighborhood Hits	60	Shared Neighborhood Hits	34
SwissProt Accessions	P06741	Gene names	MYL1
Domain Architecture
Description	Myosin light chain 3, skeletal muscle isoform (A2 catalytic) (Alkali myosin light chain 3) (MLC3F).

MLE1_MOUSE
NC score	0.187554 (rank : 122)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	141	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	P05977	Gene names	Myl1, Mylf
Domain Architecture
Description	Myosin light chain 1, skeletal muscle isoform (MLC1F) (A1 catalytic) (Alkali myosin light chain 1).

MYL3_MOUSE
NC score	0.186360 (rank : 123)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	141	Target Neighborhood Hits	70	Shared Neighborhood Hits	35
SwissProt Accessions	P09542, Q3UIF4, Q9CQZ2	Gene names	Myl3, Mlc1v, Mylc
Domain Architecture
Description	Myosin light polypeptide 3 (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular/slow twitch myosin alkali light chain).

MLE3_MOUSE
NC score	0.186065 (rank : 124)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	141	Target Neighborhood Hits	66	Shared Neighborhood Hits	34
SwissProt Accessions	P05978	Gene names	Myl1, Mylf
Domain Architecture
Description	Myosin light chain 3, skeletal muscle isoform (A2 catalytic) (Alkali myosin light chain 3) (MLC3F).

MLRS_MOUSE
NC score	0.185324 (rank : 125)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	141	Target Neighborhood Hits	72	Shared Neighborhood Hits	41
SwissProt Accessions	P97457	Gene names	Mylpf
Domain Architecture
Description	Myosin regulatory light chain 2, skeletal muscle isoform (MLC2F).

RCN1_HUMAN
NC score	0.185293 (rank : 126)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	141	Target Neighborhood Hits	105	Shared Neighborhood Hits	71
SwissProt Accessions	Q15293	Gene names	RCN1, RCN
Domain Architecture
Description	Reticulocalbin-1 precursor.

EFHD2_HUMAN
NC score	0.182393 (rank : 127)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	141	Target Neighborhood Hits	86	Shared Neighborhood Hits	55
SwissProt Accessions	Q96C19	Gene names	EFHD2, SWS1
Domain Architecture
Description	EF-hand domain-containing protein 2 (Swiprosin-1).

MYL3_HUMAN
NC score	0.181687 (rank : 128)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	141	Target Neighborhood Hits	66	Shared Neighborhood Hits	35
SwissProt Accessions	P08590, Q9NRS8	Gene names	MYL3
Domain Architecture
Description	Myosin light polypeptide 3 (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB) (Ventricular/slow twitch myosin alkali light chain) (Cardiac myosin light chain-1) (CMLC1).

MCFD2_HUMAN
NC score	0.176503 (rank : 129)	θ value	0.365318 (rank : 85)
Query Neighborhood Hits	141	Target Neighborhood Hits	62	Shared Neighborhood Hits	44
SwissProt Accessions	Q8NI22, Q8N3M5	Gene names	MCFD2, SDNSF
Domain Architecture
Description	Multiple coagulation factor deficiency protein 2 precursor (Neural stem cell-derived neuronal survival protein).

MYL4_MOUSE
NC score	0.174737 (rank : 130)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	141	Target Neighborhood Hits	63	Shared Neighborhood Hits	34
SwissProt Accessions	P09541	Gene names	Myl4, Mlc1a, Myla
Domain Architecture
Description	Myosin light polypeptide 4 (Myosin light chain 1, atrial/fetal isoform) (MLC1A) (MLC1EMB).

MYL4_HUMAN
NC score	0.174723 (rank : 131)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	141	Target Neighborhood Hits	66	Shared Neighborhood Hits	33
SwissProt Accessions	P12829, P11783	Gene names	MYL4, MLC1
Domain Architecture
Description	Myosin light polypeptide 4 (Myosin light chain 1, embryonic muscle/atrial isoform) (Myosin light chain alkali, GT-1 isoform).

CALU_MOUSE
NC score	0.174186 (rank : 132)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	141	Target Neighborhood Hits	113	Shared Neighborhood Hits	77
SwissProt Accessions	O35887	Gene names	Calu
Domain Architecture
Description	Calumenin precursor (Crocalbin).

PEF1_HUMAN
NC score	0.168916 (rank : 133)	θ value	3.0926 (rank : 121)
Query Neighborhood Hits	141	Target Neighborhood Hits	135	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UBV8	Gene names	PEF1, ABP32
Domain Architecture	No domain graphic available
Description	Peflin (PEF protein with a long N-terminal hydrophobic domain) (Penta- EF hand domain-containing protein 1).

CALU_HUMAN
NC score	0.165042 (rank : 134)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	141	Target Neighborhood Hits	114	Shared Neighborhood Hits	74
SwissProt Accessions	O43852, O60456, Q6FHB9, Q96RL3, Q9NR43	Gene names	CALU
Domain Architecture
Description	Calumenin precursor (Crocalbin) (IEF SSP 9302).

MCFD2_MOUSE
NC score	0.161688 (rank : 135)	θ value	0.813845 (rank : 94)
Query Neighborhood Hits	141	Target Neighborhood Hits	61	Shared Neighborhood Hits	44
SwissProt Accessions	Q8K5B2, Q3U9G5	Gene names	Mcfd2, Sdnsf
Domain Architecture
Description	Multiple coagulation factor deficiency protein 2 homolog precursor (Neural stem cell-derived neuronal survival protein).

RCN1_MOUSE
NC score	0.160461 (rank : 136)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	141	Target Neighborhood Hits	91	Shared Neighborhood Hits	62
SwissProt Accessions	Q05186, Q3TVU3	Gene names	Rcn1, Rca1, Rcn
Domain Architecture
Description	Reticulocalbin-1 precursor.

DJBP_HUMAN
NC score	0.158393 (rank : 137)	θ value	1.06291 (rank : 96)
Query Neighborhood Hits	141	Target Neighborhood Hits	156	Shared Neighborhood Hits	54
SwissProt Accessions	Q5THR3, Q5U5T6, Q9BY88, Q9H5C4, Q9NSF5	Gene names	DJBP, KIAA1672
Domain Architecture	No domain graphic available
Description	DJ-1-binding protein (CAP-binding protein complex-interacting protein 1).

GPDM_MOUSE
NC score	0.157816 (rank : 138)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	141	Target Neighborhood Hits	101	Shared Neighborhood Hits	47
SwissProt Accessions	Q64521, Q61507	Gene names	Gpd2, Gdm1
Domain Architecture
Description	Glycerol-3-phosphate dehydrogenase, mitochondrial precursor (EC 1.1.99.5) (GPD-M) (GPDH-M).

EFHB_HUMAN
NC score	0.155932 (rank : 139)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	141	Target Neighborhood Hits	125	Shared Neighborhood Hits	71
SwissProt Accessions	Q8N7U6, Q6ZWK9, Q8IV58, Q96LQ6	Gene names	EFHB
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

NOX5_HUMAN
NC score	0.147489 (rank : 140)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	141	Target Neighborhood Hits	89	Shared Neighborhood Hits	55
SwissProt Accessions	Q96PH1, Q8TEQ1, Q8TER4, Q96PH2, Q96PJ8, Q96PJ9, Q9H6E0, Q9HAM8	Gene names	NOX5
Domain Architecture	No domain graphic available
Description	NADPH oxidase 5 (EC 1.6.3.-).

DGKA_MOUSE
NC score	0.138072 (rank : 141)	θ value	0.163984 (rank : 71)
Query Neighborhood Hits	141	Target Neighborhood Hits	146	Shared Neighborhood Hits	62
SwissProt Accessions	O88673, Q922X2	Gene names	Dgka, Dagk1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

EFCB3_MOUSE
NC score	0.129791 (rank : 142)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	141	Target Neighborhood Hits	65	Shared Neighborhood Hits	38
SwissProt Accessions	Q80X60	Gene names	Efcab3
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 3.

SPTA2_HUMAN
NC score	0.129020 (rank : 143)	θ value	0.0563607 (rank : 66)
Query Neighborhood Hits	141	Target Neighborhood Hits	888	Shared Neighborhood Hits	82
SwissProt Accessions	Q13813, Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0	Gene names	SPTAN1, SPTA2
Domain Architecture
Description	Spectrin alpha chain, brain (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain).

AIF1_MOUSE
NC score	0.125720 (rank : 144)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	141	Target Neighborhood Hits	41	Shared Neighborhood Hits	29
SwissProt Accessions	O70200	Gene names	Aif1, Iba1
Domain Architecture	No domain graphic available
Description	Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1).

SORCN_HUMAN
NC score	0.124046 (rank : 145)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	141	Target Neighborhood Hits	82	Shared Neighborhood Hits	43
SwissProt Accessions	P30626	Gene names	SRI
Domain Architecture
Description	Sorcin (22 kDa protein) (CP-22) (V19).

EFCB3_HUMAN
NC score	0.123661 (rank : 146)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	141	Target Neighborhood Hits	50	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N7B9	Gene names	EFCAB3
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 3.

PPE1_HUMAN
NC score	0.123009 (rank : 147)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	141	Target Neighborhood Hits	137	Shared Neighborhood Hits	74
SwissProt Accessions	O14829, O15253, Q9NU21, Q9UJH0	Gene names	PPEF1, PPEF, PPP7C
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 1 (EC 3.1.3.16) (PPEF-1) (Protein phosphatase with EF calcium-binding domain) (PPEF) (Serine/threonine-protein phosphatase 7) (PP7).

IBA2_MOUSE
NC score	0.119785 (rank : 148)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	141	Target Neighborhood Hits	49	Shared Neighborhood Hits	29
SwissProt Accessions	Q9EQX4, Q8C150	Gene names	Iba2
Domain Architecture	No domain graphic available
Description	Ionized calcium-binding adapter molecule 2.

AIF1_HUMAN
NC score	0.119712 (rank : 149)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	141	Target Neighborhood Hits	44	Shared Neighborhood Hits	30
SwissProt Accessions	P55008, Q9UKS9	Gene names	AIF1, G1, IBA1
Domain Architecture
Description	Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (Protein G1).

SORCN_MOUSE
NC score	0.118846 (rank : 150)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	141	Target Neighborhood Hits	72	Shared Neighborhood Hits	38
SwissProt Accessions	Q6P069, Q3UKC5, Q9CR38, Q9D7V8	Gene names	Sri
Domain Architecture	No domain graphic available
Description	Sorcin.

PCAT1_MOUSE
NC score	0.118615 (rank : 151)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	141	Target Neighborhood Hits	78	Shared Neighborhood Hits	51
SwissProt Accessions	Q3TFD2, Q3TAX4, Q6NXZ6, Q8BG23, Q8BUX7, Q99JU6	Gene names	Aytl2, Lpcat1
Domain Architecture	No domain graphic available
Description	1-acylglycerophosphocholine O-acyltransferase 1 (EC 2.3.1.23) (Lung- type acyl-coa:lysophosphatidylcholine acyltransferase 1) (mLPCAT1) (Acyltransferase-like 2).

IBA2_HUMAN
NC score	0.118514 (rank : 152)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	141	Target Neighborhood Hits	45	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BQI0, Q6ZR40, Q8NAX7, Q8WU47, Q9H9G0	Gene names	IBA2, C9orf58
Domain Architecture	No domain graphic available
Description	Ionized calcium-binding adapter molecule 2.

CAB45_MOUSE
NC score	0.118395 (rank : 153)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	141	Target Neighborhood Hits	82	Shared Neighborhood Hits	48
SwissProt Accessions	Q61112, Q61113	Gene names	Sdf4, Cab45
Domain Architecture	No domain graphic available
Description	45 kDa calcium-binding protein precursor (Cab45) (Stromal cell-derived factor 4) (SDF-4).

CPNS1_MOUSE
NC score	0.115337 (rank : 154)	θ value	1.81305 (rank : 106)
Query Neighborhood Hits	141	Target Neighborhood Hits	60	Shared Neighborhood Hits	40
SwissProt Accessions	O88456, Q3V0X5, Q5BKQ2, Q8CEI2, Q8VEK4, Q9R1C5	Gene names	Capns1, Capn4
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

PCAT1_HUMAN
NC score	0.114405 (rank : 155)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	141	Target Neighborhood Hits	80	Shared Neighborhood Hits	53
SwissProt Accessions	Q8NF37, Q1HAQ1, Q7Z4G6, Q8N3U7, Q8WUL8, Q9GZW6	Gene names	AYTL2, LPCAT1, PFAAP3
Domain Architecture	No domain graphic available
Description	1-acylglycerophosphocholine O-acyltransferase 1 (EC 2.3.1.23) (Lung- type acyl-coa:lysophosphatidylcholine acyltransferase 1) (Acyltransferase-like 2) (Phosphonoformate immuno-associated protein 3).

DGKA_HUMAN
NC score	0.114038 (rank : 156)	θ value	0.279714 (rank : 75)
Query Neighborhood Hits	141	Target Neighborhood Hits	151	Shared Neighborhood Hits	52
SwissProt Accessions	P23743, O75481, O75482, O75483	Gene names	DGKA, DAGK, DAGK1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

TESC_HUMAN
NC score	0.112780 (rank : 157)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	141	Target Neighborhood Hits	64	Shared Neighborhood Hits	45
SwissProt Accessions	Q96BS2	Gene names	TESC
Domain Architecture	No domain graphic available
Description	Tescalcin (TSC).

CAB45_HUMAN
NC score	0.110443 (rank : 158)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	141	Target Neighborhood Hits	60	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BRK5, Q8NBQ3, Q9NZP7	Gene names	SDF4, CAB45
Domain Architecture
Description	45 kDa calcium-binding protein precursor (Cab45) (Stromal cell-derived factor 4) (SDF-4).

CPNS1_HUMAN
NC score	0.105469 (rank : 159)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	141	Target Neighborhood Hits	57	Shared Neighborhood Hits	37
SwissProt Accessions	P04632, Q8WTX3, Q96EW0	Gene names	CAPNS1, CAPN4, CAPNS
Domain Architecture
Description	Calpain small subunit 1 (CSS1) (Calcium-dependent protease small subunit 1) (Calcium-dependent protease small subunit) (CDPS) (Calpain regulatory subunit) (Calcium-activated neutral proteinase small subunit) (CANP small subunit).

CAN1_HUMAN
NC score	0.104211 (rank : 160)	θ value	0.0330416 (rank : 60)
Query Neighborhood Hits	141	Target Neighborhood Hits	85	Shared Neighborhood Hits	54
SwissProt Accessions	P07384	Gene names	CAPN1, CANPL1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

GRAN_HUMAN
NC score	0.103135 (rank : 161)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	141	Target Neighborhood Hits	57	Shared Neighborhood Hits	37
SwissProt Accessions	P28676	Gene names	GCA, GCL
Domain Architecture
Description	Grancalcin.

CPNS2_HUMAN
NC score	0.101732 (rank : 162)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	141	Target Neighborhood Hits	66	Shared Neighborhood Hits	42
SwissProt Accessions	Q96L46, Q9BPV4	Gene names	CAPNS2
Domain Architecture
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

DGKG_MOUSE
NC score	0.101534 (rank : 163)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	141	Target Neighborhood Hits	188	Shared Neighborhood Hits	59
SwissProt Accessions	Q91WG7	Gene names	Dgkg, Dagk3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma) (88 kDa diacylglycerol kinase).

ACTN2_HUMAN
NC score	0.100326 (rank : 164)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	141	Target Neighborhood Hits	295	Shared Neighborhood Hits	56
SwissProt Accessions	P35609, Q86TF4, Q86TI8	Gene names	ACTN2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

UBP32_HUMAN
NC score	0.100228 (rank : 165)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	141	Target Neighborhood Hits	170	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

CAN1_MOUSE
NC score	0.098404 (rank : 166)	θ value	2.36792 (rank : 110)
Query Neighborhood Hits	141	Target Neighborhood Hits	83	Shared Neighborhood Hits	47
SwissProt Accessions	O35350, O88666	Gene names	Capn1, Canp1, Capa1
Domain Architecture
Description	Calpain-1 catalytic subunit (EC 3.4.22.52) (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (muCANP) (Micromolar-calpain).

ACTN2_MOUSE
NC score	0.098371 (rank : 167)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	141	Target Neighborhood Hits	287	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JI91	Gene names	Actn2
Domain Architecture
Description	Alpha-actinin-2 (Alpha actinin skeletal muscle isoform 2) (F-actin cross-linking protein).

TESC_MOUSE
NC score	0.096963 (rank : 168)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	141	Target Neighborhood Hits	63	Shared Neighborhood Hits	45
SwissProt Accessions	Q9JKL5	Gene names	Tesc
Domain Architecture	No domain graphic available
Description	Tescalcin (TSC).

PKD2_HUMAN
NC score	0.094606 (rank : 169)	θ value	0.0148317 (rank : 55)
Query Neighborhood Hits	141	Target Neighborhood Hits	105	Shared Neighborhood Hits	17
SwissProt Accessions	Q13563, O60441, Q15764	Gene names	PKD2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog) (Autosomal dominant polycystic kidney disease type II protein) (Polycystwin) (R48321).

CAYP2_HUMAN
NC score	0.093676 (rank : 170)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	141	Target Neighborhood Hits	98	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BXY5, Q6PH84, Q8N242, Q8NAY5	Gene names	CAPS2
Domain Architecture
Description	Calcyphosin-2 (Calcyphosine-2).

PKD2_MOUSE
NC score	0.093618 (rank : 171)	θ value	0.0113563 (rank : 52)
Query Neighborhood Hits	141	Target Neighborhood Hits	99	Shared Neighborhood Hits	19
SwissProt Accessions	O35245, Q9QWP0, Q9Z193, Q9Z194	Gene names	Pkd2
Domain Architecture
Description	Polycystin-2 (Polycystic kidney disease 2 protein homolog).

DGKG_HUMAN
NC score	0.093005 (rank : 172)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	141	Target Neighborhood Hits	171	Shared Neighborhood Hits	55
SwissProt Accessions	P49619	Gene names	DGKG, DAGK3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma).

ACTN3_HUMAN
NC score	0.091987 (rank : 173)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	141	Target Neighborhood Hits	272	Shared Neighborhood Hits	49
SwissProt Accessions	Q08043	Gene names	ACTN3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

ACTN3_MOUSE
NC score	0.091971 (rank : 174)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	141	Target Neighborhood Hits	265	Shared Neighborhood Hits	49
SwissProt Accessions	O88990	Gene names	Actn3
Domain Architecture
Description	Alpha-actinin-3 (Alpha actinin skeletal muscle isoform 3) (F-actin cross-linking protein).

PPE2_MOUSE
NC score	0.091910 (rank : 175)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	141	Target Neighborhood Hits	112	Shared Neighborhood Hits	59
SwissProt Accessions	O35385	Gene names	Ppef2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

ACTN1_HUMAN
NC score	0.091111 (rank : 176)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	141	Target Neighborhood Hits	221	Shared Neighborhood Hits	54
SwissProt Accessions	P12814, Q9BTN1	Gene names	ACTN1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

ACTN4_HUMAN
NC score	0.091064 (rank : 177)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	141	Target Neighborhood Hits	279	Shared Neighborhood Hits	55
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

ACTN1_MOUSE
NC score	0.090596 (rank : 178)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	141	Target Neighborhood Hits	216	Shared Neighborhood Hits	53
SwissProt Accessions	Q7TPR4	Gene names	Actn1
Domain Architecture
Description	Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (Non-muscle alpha-actinin-1) (F-actin cross-linking protein).

S100G_HUMAN
NC score	0.088574 (rank : 179)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	141	Target Neighborhood Hits	103	Shared Neighborhood Hits	48
SwissProt Accessions	P29377	Gene names	S100G, CABP9K, CALB3, S100D
Domain Architecture
Description	Protein S100-G (S100 calcium-binding protein G) (Vitamin D-dependent calcium-binding protein, intestinal) (CABP) (Calbindin D9K).

ACTN4_MOUSE
NC score	0.087607 (rank : 180)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	141	Target Neighborhood Hits	276	Shared Neighborhood Hits	54
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

EFHC1_MOUSE
NC score	0.086264 (rank : 181)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	141	Target Neighborhood Hits	65	Shared Neighborhood Hits	44
SwissProt Accessions	Q9D9T8	Gene names	Efhc1
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing protein 1.

CAN3_MOUSE
NC score	0.085787 (rank : 182)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	141	Target Neighborhood Hits	115	Shared Neighborhood Hits	34
SwissProt Accessions	Q64691, Q9WUC5	Gene names	Capn3
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3).

MACF1_MOUSE
NC score	0.083788 (rank : 183)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	141	Target Neighborhood Hits	1313	Shared Neighborhood Hits	89
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

GRAN_MOUSE
NC score	0.083634 (rank : 184)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	141	Target Neighborhood Hits	53	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VC88, Q8BL53, Q8K3Z6	Gene names	Gca
Domain Architecture	No domain graphic available
Description	Grancalcin.

CAN3_HUMAN
NC score	0.082844 (rank : 185)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	141	Target Neighborhood Hits	96	Shared Neighborhood Hits	42
SwissProt Accessions	P20807, Q9BTU4, Q9Y5S6, Q9Y5S7	Gene names	CAPN3, CANP3, CANPL3, NCL1
Domain Architecture
Description	Calpain-3 (EC 3.4.22.-) (Calpain L3) (Calpain p94) (Calcium-activated neutral proteinase 3) (CANP 3) (Muscle-specific calcium-activated neutral protease 3) (nCL-1).

MACF4_HUMAN
NC score	0.082536 (rank : 186)	θ value	0.365318 (rank : 84)
Query Neighborhood Hits	141	Target Neighborhood Hits	1321	Shared Neighborhood Hits	85
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MACF1_HUMAN
NC score	0.082307 (rank : 187)	θ value	0.365318 (rank : 83)
Query Neighborhood Hits	141	Target Neighborhood Hits	1341	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

PPE2_HUMAN
NC score	0.081431 (rank : 188)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	141	Target Neighborhood Hits	106	Shared Neighborhood Hits	51
SwissProt Accessions	O14830, O14831	Gene names	PPEF2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

BPA1_MOUSE
NC score	0.077756 (rank : 189)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	141	Target Neighborhood Hits	1477	Shared Neighborhood Hits	86
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_HUMAN
NC score	0.075589 (rank : 190)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	141	Target Neighborhood Hits	1369	Shared Neighborhood Hits	82
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

RHBD4_HUMAN
NC score	0.073898 (rank : 191)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	141	Target Neighborhood Hits	69	Shared Neighborhood Hits	40
SwissProt Accessions	P58872	Gene names	RHBDL4, VRHO
Domain Architecture
Description	Rhomboid-related protein 4 (EC 3.4.21.105) (Ventrhoid transmembrane protein).

EFHB_MOUSE
NC score	0.073421 (rank : 192)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	141	Target Neighborhood Hits	120	Shared Neighborhood Hits	42
SwissProt Accessions	Q8CDU5	Gene names	Efhb
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member B.

CPNS2_MOUSE
NC score	0.072710 (rank : 193)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	141	Target Neighborhood Hits	46	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D7J7	Gene names	Capns2
Domain Architecture	No domain graphic available
Description	Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).

RHBD4_MOUSE
NC score	0.068096 (rank : 194)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	141	Target Neighborhood Hits	61	Shared Neighborhood Hits	35
SwissProt Accessions	P58873	Gene names	Rhbdl4, Vrho
Domain Architecture
Description	Rhomboid-related protein 4 (EC 3.4.21.105) (Ventrhoid transmembrane protein).

EFHC1_HUMAN
NC score	0.066861 (rank : 195)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	141	Target Neighborhood Hits	61	Shared Neighborhood Hits	32
SwissProt Accessions	Q5JVL4, Q5XKM4, Q6E1U7, Q6E1U8, Q8WUL2, Q9NVW6	Gene names	EFHC1
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing protein 1.

FKBP9_MOUSE
NC score	0.063367 (rank : 196)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	141	Target Neighborhood Hits	77	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Z247, Q80ZZ6, Q8R386, Q9CVM0, Q9JHX5	Gene names	Fkbp9, Fkbp60, Fkbp63
Domain Architecture
Description	FK506-binding protein 9 precursor (EC 5.2.1.8) (Peptidyl-prolyl cis- trans isomerase) (PPIase) (Rotamase) (FKBP65RS).

SPTA1_HUMAN
NC score	0.063069 (rank : 197)	θ value	0.21417 (rank : 74)
Query Neighborhood Hits	141	Target Neighborhood Hits	748	Shared Neighborhood Hits	32
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

CAN9_HUMAN
NC score	0.061833 (rank : 198)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	141	Target Neighborhood Hits	68	Shared Neighborhood Hits	37
SwissProt Accessions	O14815, Q9NS74	Gene names	CAPN9, NCL4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4) (CG36 protein).

CAN9_MOUSE
NC score	0.061031 (rank : 199)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	141	Target Neighborhood Hits	73	Shared Neighborhood Hits	39
SwissProt Accessions	Q9D805, O35919	Gene names	Capn9, Ncl4
Domain Architecture
Description	Calpain-9 (EC 3.4.22.-) (Digestive tract-specific calpain) (nCL-4).

CAN2_HUMAN
NC score	0.059261 (rank : 200)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	141	Target Neighborhood Hits	71	Shared Neighborhood Hits	32
SwissProt Accessions	P17655, Q16738, Q6PJT3, Q8WU26, Q9HBB1	Gene names	CAPN2, CANPL2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (Calpain large polypeptide L2).

CAN11_HUMAN
NC score	0.058857 (rank : 201)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	141	Target Neighborhood Hits	63	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UMQ6, Q8N4R5	Gene names	CAPN11
Domain Architecture
Description	Calpain-11 (EC 3.4.22.-) (Calcium-activated neutral proteinase 11) (CANP 11).

FKBP9_HUMAN
NC score	0.056158 (rank : 202)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	141	Target Neighborhood Hits	72	Shared Neighborhood Hits	42
SwissProt Accessions	O95302, Q3MIR7, Q6IN76, Q6P2N1, Q96EX5, Q96IJ9	Gene names	FKBP9, FKBP60, FKBP63
Domain Architecture	No domain graphic available
Description	FK506-binding protein 9 precursor (EC 5.2.1.8) (Peptidyl-prolyl cis- trans isomerase) (PPIase) (Rotamase).

EGLX_HUMAN
NC score	0.055734 (rank : 203)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	141	Target Neighborhood Hits	43	Shared Neighborhood Hits	29
SwissProt Accessions	Q9NXG6, Q6PAG6, Q8TCJ9, Q8WV55, Q96F22, Q9BW77	Gene names	PH4
Domain Architecture
Description	Putative HIF-prolyl hydroxylase PH-4 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl 4-hydroxylase).

S100G_MOUSE
NC score	0.055629 (rank : 204)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	141	Target Neighborhood Hits	87	Shared Neighborhood Hits	39
SwissProt Accessions	P97816	Gene names	S100g, Calb3, S100d
Domain Architecture
Description	Protein S100-G (S100 calcium-binding protein G) (Vitamin D-dependent calcium-binding protein, intestinal) (CABP) (Calbindin D9K).

EGLX_MOUSE
NC score	0.055441 (rank : 205)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	141	Target Neighborhood Hits	49	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BG58, Q8CAF1, Q9D499	Gene names	Ph4
Domain Architecture
Description	Putative HIF-prolyl hydroxylase PH-4 (EC 1.14.11.-) (Hypoxia-inducible factor prolyl 4-hydroxylase).

CAN2_MOUSE
NC score	0.054611 (rank : 206)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	141	Target Neighborhood Hits	69	Shared Neighborhood Hits	27
SwissProt Accessions	O08529, O35518, O54843	Gene names	Capn2
Domain Architecture
Description	Calpain-2 catalytic subunit precursor (EC 3.4.22.53) (Calpain-2 large subunit) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M- type) (M-calpain) (Millimolar-calpain) (80 kDa M-calpain subunit) (CALP80).

NUCB2_MOUSE
NC score	0.054426 (rank : 207)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	141	Target Neighborhood Hits	459	Shared Neighborhood Hits	47
SwissProt Accessions	P81117	Gene names	Nucb2, Nefa
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA).

EFHA2_HUMAN
NC score	0.054120 (rank : 208)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	141	Target Neighborhood Hits	61	Shared Neighborhood Hits	26
SwissProt Accessions	Q86XE3, Q8IYZ3	Gene names	EFHA2
Domain Architecture	No domain graphic available
Description	EF-hand domain-containing family member A2.

NUCB2_HUMAN
NC score	0.052025 (rank : 209)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	141	Target Neighborhood Hits	321	Shared Neighborhood Hits	38
SwissProt Accessions	P80303, Q8NFT5	Gene names	NUCB2, NEFA
Domain Architecture	No domain graphic available
Description	Nucleobindin-2 precursor (DNA-binding protein NEFA) (Gastric cancer antigen Zg4).

PK2L1_HUMAN
NC score	0.050738 (rank : 210)	θ value	2.36792 (rank : 112)
Query Neighborhood Hits	141	Target Neighborhood Hits	132	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P0L9, O75972, Q9UP35, Q9UPA2	Gene names	PKD2L1, PKD2L, PKDL
Domain Architecture
Description	Polycystic kidney disease 2-like 1 protein (Polycystin-L) (Polycystin- 2 homolog).

FKB10_MOUSE
NC score	0.050362 (rank : 211)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	141	Target Neighborhood Hits	66	Shared Neighborhood Hits	32
SwissProt Accessions	Q61576, Q8VHI1	Gene names	Fkbp10, Fkbp-rs, Fkbp1-rs, Fkbp6, Fkbprp
Domain Architecture
Description	FK506-binding protein 10 precursor (EC 5.2.1.8) (Peptidyl-prolyl cis- trans isomerase) (PPIase) (Rotamase) (65 kDa FK506-binding protein) (FKBP65) (Immunophilin FKBP65).

FA8_HUMAN
NC score	0.047764 (rank : 212)	θ value	0.0330416 (rank : 61)
Query Neighborhood Hits	141	Target Neighborhood Hits	112	Shared Neighborhood Hits	5
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

FA8_MOUSE
NC score	0.040531 (rank : 213)	θ value	0.365318 (rank : 81)
Query Neighborhood Hits	141	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

FKB10_HUMAN
NC score	0.040376 (rank : 214)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	141	Target Neighborhood Hits	61	Shared Neighborhood Hits	28
SwissProt Accessions	Q96AY3, Q7Z3R4, Q9H3N3, Q9H6N5, Q9UF89	Gene names	FKBP10, FKBP65
Domain Architecture
Description	FK506-binding protein 10 precursor (EC 5.2.1.8) (Peptidyl-prolyl cis- trans isomerase) (PPIase) (Rotamase) (65 kDa FK506-binding protein) (FKBP65) (Immunophilin FKBP65).

FKBP7_MOUSE
NC score	0.039839 (rank : 215)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	141	Target Neighborhood Hits	58	Shared Neighborhood Hits	25
SwissProt Accessions	O54998	Gene names	Fkbp7, Fkbp23
Domain Architecture
Description	FK506-binding protein 7 precursor (EC 5.2.1.8) (Peptidyl-prolyl cis- trans isomerase) (PPIase) (Rotamase) (FKBP-23).

PLCD1_HUMAN
NC score	0.031741 (rank : 216)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	141	Target Neighborhood Hits	93	Shared Neighborhood Hits	6
SwissProt Accessions	P51178	Gene names	PLCD1
Domain Architecture
Description	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta 1 (EC 3.1.4.11) (Phosphoinositide phospholipase C) (PLC-delta-1) (Phospholipase C-delta-1) (PLC-III).

SCN7A_HUMAN
NC score	0.027071 (rank : 217)	θ value	2.36792 (rank : 113)
Query Neighborhood Hits	141	Target Neighborhood Hits	135	Shared Neighborhood Hits	16
SwissProt Accessions	Q01118	Gene names	SCN7A, SCN6A
Domain Architecture
Description	Sodium channel protein type 7 subunit alpha (Sodium channel protein type VII subunit alpha) (Putative voltage-gated sodium channel alpha subunit Nax) (Sodium channel protein, cardiac and skeletal muscle alpha-subunit).

2ACC_HUMAN
NC score	0.020995 (rank : 218)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	141	Target Neighborhood Hits	21	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5P8	Gene names	PPP2R3B, PPP2R3L
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 48 kDa regulatory subunit B (PP2A, subunit B, PR48 isoform).

SCN3A_HUMAN
NC score	0.020468 (rank : 219)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	141	Target Neighborhood Hits	115	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

SCN9A_HUMAN
NC score	0.020224 (rank : 220)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	141	Target Neighborhood Hits	157	Shared Neighborhood Hits	15
SwissProt Accessions	Q15858, Q6B4R9, Q6B4S0, Q6B4S1, Q70HX1, Q70HX2, Q8WTU1, Q8WWN4	Gene names	SCN9A, NENA, PN1
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1).

SCN2A_HUMAN
NC score	0.019652 (rank : 221)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	141	Target Neighborhood Hits	157	Shared Neighborhood Hits	16
SwissProt Accessions	Q99250, Q14472, Q9BZC9, Q9BZD0	Gene names	SCN2A, NAC2, SCN2A2
Domain Architecture
Description	Sodium channel protein type 2 subunit alpha (Sodium channel protein type II subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.2) (Sodium channel protein, brain II subunit alpha) (HBSC II).

SCN1A_HUMAN
NC score	0.019650 (rank : 222)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	141	Target Neighborhood Hits	148	Shared Neighborhood Hits	15
SwissProt Accessions	P35498, Q16172, Q96LA3, Q9C008	Gene names	SCN1A, NAC1, SCN1
Domain Architecture
Description	Sodium channel protein type 1 subunit alpha (Sodium channel protein type I subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.1) (Sodium channel protein, brain I subunit alpha).

SCN8A_MOUSE
NC score	0.019190 (rank : 223)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	141	Target Neighborhood Hits	136	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WTU3, Q60828, Q60858, Q62449	Gene names	Scn8a, Nbna1
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

SCN8A_HUMAN
NC score	0.019113 (rank : 224)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	141	Target Neighborhood Hits	135	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UQD0, O95788, Q9NYX2, Q9UPB2	Gene names	SCN8A
Domain Architecture
Description	Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6).

TBC19_HUMAN
NC score	0.017312 (rank : 225)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	141	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N5T2	Gene names	TBC1D19
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 19.

GOGA4_HUMAN
NC score	0.011438 (rank : 226)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	141	Target Neighborhood Hits	2034	Shared Neighborhood Hits	20
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

KTN1_MOUSE
NC score	0.010458 (rank : 227)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	141	Target Neighborhood Hits	1324	Shared Neighborhood Hits	14
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

FRAS1_MOUSE
NC score	0.009015 (rank : 228)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	141	Target Neighborhood Hits	747	Shared Neighborhood Hits	4
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

GCC1_MOUSE
NC score	0.006468 (rank : 229)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	141	Target Neighborhood Hits	777	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).