Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : STAT2_MOUSE

For an explanation of this page, click here

STAT2_MOUSE
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

STAT2_HUMAN
θ value	0 (rank : 1)	NC score	0.945423 (rank : 2)
Query Neighborhood Hits	175	Target Neighborhood Hits	99	Shared Neighborhood Hits	31
SwissProt Accessions	P52630, Q16430, Q16431	Gene names	STAT2
Domain Architecture
Description	Signal transducer and activator of transcription 2 (p113).

STAT2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	175	Target Neighborhood Hits	175	Shared Neighborhood Hits	175
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

STAT1_HUMAN
θ value	2.77624e-142 (rank : 3)	NC score	0.914295 (rank : 5)
Query Neighborhood Hits	175	Target Neighborhood Hits	128	Shared Neighborhood Hits	22
SwissProt Accessions	P42224	Gene names	STAT1
Domain Architecture
Description	Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84).

STAT1_MOUSE
θ value	1.98959e-140 (rank : 4)	NC score	0.913431 (rank : 6)
Query Neighborhood Hits	175	Target Neighborhood Hits	151	Shared Neighborhood Hits	25
SwissProt Accessions	P42225	Gene names	Stat1
Domain Architecture
Description	Signal transducer and activator of transcription 1.

STAT4_HUMAN
θ value	1.80368e-133 (rank : 5)	NC score	0.915475 (rank : 4)
Query Neighborhood Hits	175	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	Q14765, Q96NZ6	Gene names	STAT4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STAT3_HUMAN
θ value	2.20485e-131 (rank : 6)	NC score	0.907802 (rank : 7)
Query Neighborhood Hits	175	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	P40763, O14916, Q9BW54	Gene names	STAT3, APRF
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT3_MOUSE
θ value	2.20485e-131 (rank : 7)	NC score	0.907801 (rank : 8)
Query Neighborhood Hits	175	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	P42227	Gene names	Stat3, Aprf
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT4_MOUSE
θ value	1.29561e-123 (rank : 8)	NC score	0.918194 (rank : 3)
Query Neighborhood Hits	175	Target Neighborhood Hits	73	Shared Neighborhood Hits	16
SwissProt Accessions	P42228	Gene names	Stat4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STA5B_HUMAN
θ value	2.3352e-48 (rank : 9)	NC score	0.821279 (rank : 9)
Query Neighborhood Hits	175	Target Neighborhood Hits	103	Shared Neighborhood Hits	23
SwissProt Accessions	P51692, Q8WWS8	Gene names	STAT5B
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STA5B_MOUSE
θ value	6.7944e-48 (rank : 10)	NC score	0.818896 (rank : 10)
Query Neighborhood Hits	175	Target Neighborhood Hits	124	Shared Neighborhood Hits	24
SwissProt Accessions	P42232, Q541Q5, Q60804, Q8K3Q1, Q9JKM1	Gene names	Stat5b
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STA5A_MOUSE
θ value	7.51208e-47 (rank : 11)	NC score	0.816370 (rank : 11)
Query Neighborhood Hits	175	Target Neighborhood Hits	128	Shared Neighborhood Hits	26
SwissProt Accessions	P42230	Gene names	Stat5a, Mgf, Mpf
Domain Architecture
Description	Signal transducer and activator of transcription 5A (Mammary gland factor).

STA5A_HUMAN
θ value	2.18568e-46 (rank : 12)	NC score	0.813506 (rank : 12)
Query Neighborhood Hits	175	Target Neighborhood Hits	140	Shared Neighborhood Hits	24
SwissProt Accessions	P42229	Gene names	STAT5A, STAT5
Domain Architecture
Description	Signal transducer and activator of transcription 5A.

STAT6_HUMAN
θ value	4.00176e-32 (rank : 13)	NC score	0.795069 (rank : 13)
Query Neighborhood Hits	175	Target Neighborhood Hits	132	Shared Neighborhood Hits	36
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

STAT6_MOUSE
θ value	7.54701e-31 (rank : 14)	NC score	0.793713 (rank : 14)
Query Neighborhood Hits	175	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	P52633	Gene names	Stat6
Domain Architecture
Description	Signal transducer and transcription activator 6.

DGKK_HUMAN
θ value	5.8054e-15 (rank : 15)	NC score	0.105414 (rank : 20)
Query Neighborhood Hits	175	Target Neighborhood Hits	378	Shared Neighborhood Hits	27
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

PRG4_HUMAN
θ value	3.52202e-12 (rank : 16)	NC score	0.102707 (rank : 22)
Query Neighborhood Hits	175	Target Neighborhood Hits	764	Shared Neighborhood Hits	34
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

GNDS_MOUSE
θ value	1.06045e-08 (rank : 17)	NC score	0.101772 (rank : 23)
Query Neighborhood Hits	175	Target Neighborhood Hits	115	Shared Neighborhood Hits	10
SwissProt Accessions	Q03385	Gene names	Ralgds, Rgds
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

PRG4_MOUSE
θ value	1.06045e-08 (rank : 18)	NC score	0.101343 (rank : 24)
Query Neighborhood Hits	175	Target Neighborhood Hits	624	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

GNDS_HUMAN
θ value	1.80886e-08 (rank : 19)	NC score	0.102960 (rank : 21)
Query Neighborhood Hits	175	Target Neighborhood Hits	201	Shared Neighborhood Hits	22
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

CIZ1_HUMAN
θ value	5.44631e-05 (rank : 20)	NC score	0.107773 (rank : 19)
Query Neighborhood Hits	175	Target Neighborhood Hits	359	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

PININ_HUMAN
θ value	0.000158464 (rank : 21)	NC score	0.057242 (rank : 56)
Query Neighborhood Hits	175	Target Neighborhood Hits	753	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

TACC3_MOUSE
θ value	0.000158464 (rank : 22)	NC score	0.046853 (rank : 72)
Query Neighborhood Hits	175	Target Neighborhood Hits	607	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

PTN23_MOUSE
θ value	0.00035302 (rank : 23)	NC score	0.038518 (rank : 91)
Query Neighborhood Hits	175	Target Neighborhood Hits	726	Shared Neighborhood Hits	48
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

PININ_MOUSE
θ value	0.000602161 (rank : 24)	NC score	0.060073 (rank : 49)
Query Neighborhood Hits	175	Target Neighborhood Hits	777	Shared Neighborhood Hits	23
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

SRBP1_MOUSE
θ value	0.000602161 (rank : 25)	NC score	0.066933 (rank : 39)
Query Neighborhood Hits	175	Target Neighborhood Hits	384	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

CDN1C_HUMAN
θ value	0.000786445 (rank : 26)	NC score	0.079005 (rank : 30)
Query Neighborhood Hits	175	Target Neighborhood Hits	168	Shared Neighborhood Hits	16
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

MOT8_MOUSE
θ value	0.00134147 (rank : 27)	NC score	0.058825 (rank : 54)
Query Neighborhood Hits	175	Target Neighborhood Hits	96	Shared Neighborhood Hits	12
SwissProt Accessions	O70324, Q8K3S9	Gene names	Slc16a2, Mct8, Xpct
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

IASPP_MOUSE
θ value	0.00175202 (rank : 28)	NC score	0.055834 (rank : 57)
Query Neighborhood Hits	175	Target Neighborhood Hits	1024	Shared Neighborhood Hits	60
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

TITIN_HUMAN
θ value	0.00228821 (rank : 29)	NC score	0.016816 (rank : 135)
Query Neighborhood Hits	175	Target Neighborhood Hits	2923	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

IASPP_HUMAN
θ value	0.00298849 (rank : 30)	NC score	0.046412 (rank : 74)
Query Neighborhood Hits	175	Target Neighborhood Hits	688	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

PHLA1_MOUSE
θ value	0.00298849 (rank : 31)	NC score	0.077292 (rank : 31)
Query Neighborhood Hits	175	Target Neighborhood Hits	103	Shared Neighborhood Hits	13
SwissProt Accessions	Q62392, Q3TY48, Q3UG87	Gene names	Phlda1, Tdag51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Proline- and glutamine-rich protein) (PQR protein).

PRAX_MOUSE
θ value	0.00298849 (rank : 32)	NC score	0.113241 (rank : 16)
Query Neighborhood Hits	175	Target Neighborhood Hits	199	Shared Neighborhood Hits	29
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

SON_HUMAN
θ value	0.00298849 (rank : 33)	NC score	0.108404 (rank : 18)
Query Neighborhood Hits	175	Target Neighborhood Hits	1568	Shared Neighborhood Hits	111
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

TAF4_HUMAN
θ value	0.00390308 (rank : 34)	NC score	0.062209 (rank : 47)
Query Neighborhood Hits	175	Target Neighborhood Hits	687	Shared Neighborhood Hits	42
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

CCAR1_HUMAN
θ value	0.00665767 (rank : 35)	NC score	0.045315 (rank : 76)
Query Neighborhood Hits	175	Target Neighborhood Hits	444	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

WNK2_HUMAN
θ value	0.00665767 (rank : 36)	NC score	0.020784 (rank : 122)
Query Neighborhood Hits	175	Target Neighborhood Hits	1407	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

MNT_MOUSE
θ value	0.00869519 (rank : 37)	NC score	0.065688 (rank : 40)
Query Neighborhood Hits	175	Target Neighborhood Hits	432	Shared Neighborhood Hits	34
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

PRAX_HUMAN
θ value	0.00869519 (rank : 38)	NC score	0.120915 (rank : 15)
Query Neighborhood Hits	175	Target Neighborhood Hits	215	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

SMCA2_HUMAN
θ value	0.00869519 (rank : 39)	NC score	0.028870 (rank : 106)
Query Neighborhood Hits	175	Target Neighborhood Hits	503	Shared Neighborhood Hits	25
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

AUTS2_HUMAN
θ value	0.0193708 (rank : 40)	NC score	0.071009 (rank : 36)
Query Neighborhood Hits	175	Target Neighborhood Hits	342	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

PHLA1_HUMAN
θ value	0.0193708 (rank : 41)	NC score	0.074677 (rank : 34)
Query Neighborhood Hits	175	Target Neighborhood Hits	121	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WV24, Q15184, Q2TAN2, Q9NZ17	Gene names	PHLDA1, PHRIP, TDAG51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Apoptosis-associated nuclear protein) (Proline- and histidine-rich protein) (Proline- and glutamine-rich protein) (PQ-rich protein).

SON_MOUSE
θ value	0.0252991 (rank : 42)	NC score	0.096439 (rank : 25)
Query Neighborhood Hits	175	Target Neighborhood Hits	957	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

ABL2_HUMAN
θ value	0.0330416 (rank : 43)	NC score	0.011642 (rank : 151)
Query Neighborhood Hits	175	Target Neighborhood Hits	1045	Shared Neighborhood Hits	31
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

PHC3_MOUSE
θ value	0.0330416 (rank : 44)	NC score	0.054534 (rank : 60)
Query Neighborhood Hits	175	Target Neighborhood Hits	194	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

SELV_HUMAN
θ value	0.0330416 (rank : 45)	NC score	0.065162 (rank : 41)
Query Neighborhood Hits	175	Target Neighborhood Hits	118	Shared Neighborhood Hits	12
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

MNT_HUMAN
θ value	0.0431538 (rank : 46)	NC score	0.067535 (rank : 37)
Query Neighborhood Hits	175	Target Neighborhood Hits	496	Shared Neighborhood Hits	46
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

SF3A1_MOUSE
θ value	0.0563607 (rank : 47)	NC score	0.059634 (rank : 51)
Query Neighborhood Hits	175	Target Neighborhood Hits	198	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

SOX30_HUMAN
θ value	0.0563607 (rank : 48)	NC score	0.038558 (rank : 89)
Query Neighborhood Hits	175	Target Neighborhood Hits	305	Shared Neighborhood Hits	39
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

WASF1_MOUSE
θ value	0.0563607 (rank : 49)	NC score	0.040415 (rank : 84)
Query Neighborhood Hits	175	Target Neighborhood Hits	261	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

ATBF1_MOUSE
θ value	0.0736092 (rank : 50)	NC score	0.024381 (rank : 117)
Query Neighborhood Hits	175	Target Neighborhood Hits	1841	Shared Neighborhood Hits	50
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BRD4_HUMAN
θ value	0.0736092 (rank : 51)	NC score	0.043879 (rank : 78)
Query Neighborhood Hits	175	Target Neighborhood Hits	851	Shared Neighborhood Hits	49
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

GGN_MOUSE
θ value	0.0736092 (rank : 52)	NC score	0.044071 (rank : 77)
Query Neighborhood Hits	175	Target Neighborhood Hits	311	Shared Neighborhood Hits	20
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

SF3A1_HUMAN
θ value	0.0736092 (rank : 53)	NC score	0.059081 (rank : 53)
Query Neighborhood Hits	175	Target Neighborhood Hits	199	Shared Neighborhood Hits	14
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

WASF1_HUMAN
θ value	0.0736092 (rank : 54)	NC score	0.041524 (rank : 82)
Query Neighborhood Hits	175	Target Neighborhood Hits	260	Shared Neighborhood Hits	18
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

FGD1_HUMAN
θ value	0.0961366 (rank : 55)	NC score	0.020331 (rank : 125)
Query Neighborhood Hits	175	Target Neighborhood Hits	367	Shared Neighborhood Hits	16
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

KIF17_MOUSE
θ value	0.0961366 (rank : 56)	NC score	0.010913 (rank : 155)
Query Neighborhood Hits	175	Target Neighborhood Hits	452	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

LDB3_HUMAN
θ value	0.0961366 (rank : 57)	NC score	0.018998 (rank : 127)
Query Neighborhood Hits	175	Target Neighborhood Hits	497	Shared Neighborhood Hits	18
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

RAPH1_HUMAN
θ value	0.0961366 (rank : 58)	NC score	0.041596 (rank : 81)
Query Neighborhood Hits	175	Target Neighborhood Hits	593	Shared Neighborhood Hits	36
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

3BP2_MOUSE
θ value	0.163984 (rank : 59)	NC score	0.037393 (rank : 94)
Query Neighborhood Hits	175	Target Neighborhood Hits	142	Shared Neighborhood Hits	20
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

CN155_HUMAN
θ value	0.163984 (rank : 60)	NC score	0.046845 (rank : 73)
Query Neighborhood Hits	175	Target Neighborhood Hits	385	Shared Neighborhood Hits	19
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

MLL2_HUMAN
θ value	0.163984 (rank : 61)	NC score	0.054709 (rank : 59)
Query Neighborhood Hits	175	Target Neighborhood Hits	1788	Shared Neighborhood Hits	81
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PRS6B_HUMAN
θ value	0.163984 (rank : 62)	NC score	0.011097 (rank : 153)
Query Neighborhood Hits	175	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	P43686, Q96FV5, Q9UBM3, Q9UEX3	Gene names	PSMC4, TBP7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7).

ABL1_HUMAN
θ value	0.21417 (rank : 63)	NC score	0.009698 (rank : 161)
Query Neighborhood Hits	175	Target Neighborhood Hits	1220	Shared Neighborhood Hits	36
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

PHC3_HUMAN
θ value	0.21417 (rank : 64)	NC score	0.049990 (rank : 67)
Query Neighborhood Hits	175	Target Neighborhood Hits	218	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

ABL1_MOUSE
θ value	0.279714 (rank : 65)	NC score	0.009795 (rank : 159)
Query Neighborhood Hits	175	Target Neighborhood Hits	1178	Shared Neighborhood Hits	36
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

BRD4_MOUSE
θ value	0.279714 (rank : 66)	NC score	0.037653 (rank : 93)
Query Neighborhood Hits	175	Target Neighborhood Hits	845	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CCAR1_MOUSE
θ value	0.279714 (rank : 67)	NC score	0.037658 (rank : 92)
Query Neighborhood Hits	175	Target Neighborhood Hits	414	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

CDN1C_MOUSE
θ value	0.279714 (rank : 68)	NC score	0.063529 (rank : 43)
Query Neighborhood Hits	175	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

GP152_MOUSE
θ value	0.279714 (rank : 69)	NC score	0.037030 (rank : 95)
Query Neighborhood Hits	175	Target Neighborhood Hits	607	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

LTBP4_MOUSE
θ value	0.279714 (rank : 70)	NC score	0.006255 (rank : 174)
Query Neighborhood Hits	175	Target Neighborhood Hits	607	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MLL4_HUMAN
θ value	0.279714 (rank : 71)	NC score	0.032429 (rank : 100)
Query Neighborhood Hits	175	Target Neighborhood Hits	722	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

MOT8_HUMAN
θ value	0.279714 (rank : 72)	NC score	0.041384 (rank : 83)
Query Neighborhood Hits	175	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	P36021, Q7Z797	Gene names	SLC16A2, MCT8, XPCT
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (MCT 7) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

ACINU_MOUSE
θ value	0.365318 (rank : 73)	NC score	0.028681 (rank : 109)
Query Neighborhood Hits	175	Target Neighborhood Hits	712	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CASB_HUMAN
θ value	0.365318 (rank : 74)	NC score	0.053405 (rank : 62)
Query Neighborhood Hits	175	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	P05814, Q4VAZ9	Gene names	CSN2, CASB
Domain Architecture	No domain graphic available
Description	Beta-casein precursor.

DHX37_HUMAN
θ value	0.365318 (rank : 75)	NC score	0.016495 (rank : 138)
Query Neighborhood Hits	175	Target Neighborhood Hits	133	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

GP152_HUMAN
θ value	0.365318 (rank : 76)	NC score	0.049629 (rank : 68)
Query Neighborhood Hits	175	Target Neighborhood Hits	636	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

IF4G1_MOUSE
θ value	0.365318 (rank : 77)	NC score	0.048816 (rank : 69)
Query Neighborhood Hits	175	Target Neighborhood Hits	534	Shared Neighborhood Hits	58
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

NTBP1_HUMAN
θ value	0.365318 (rank : 78)	NC score	0.038522 (rank : 90)
Query Neighborhood Hits	175	Target Neighborhood Hits	171	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T7V8, Q49A22, Q6P1P9, Q9HAE6, Q9Y350	Gene names	SCYL1BP1, NTKLBP1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (hNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

PRR12_HUMAN
θ value	0.365318 (rank : 79)	NC score	0.050754 (rank : 64)
Query Neighborhood Hits	175	Target Neighborhood Hits	460	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

CI079_HUMAN
θ value	0.47712 (rank : 80)	NC score	0.039989 (rank : 86)
Query Neighborhood Hits	175	Target Neighborhood Hits	288	Shared Neighborhood Hits	23
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

FRAT1_HUMAN
θ value	0.47712 (rank : 81)	NC score	0.025970 (rank : 111)
Query Neighborhood Hits	175	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q92837, Q8NE74, Q8TDW9	Gene names	FRAT1
Domain Architecture
Description	Proto-oncogene FRAT1 (Frequently rearranged in advanced T-cell lymphomas) (Frat-1).

MTF1_HUMAN
θ value	0.47712 (rank : 82)	NC score	0.000379 (rank : 188)
Query Neighborhood Hits	175	Target Neighborhood Hits	814	Shared Neighborhood Hits	17
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

PHC1_HUMAN
θ value	0.47712 (rank : 83)	NC score	0.039031 (rank : 87)
Query Neighborhood Hits	175	Target Neighborhood Hits	227	Shared Neighborhood Hits	21
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

LMBL3_MOUSE
θ value	0.62314 (rank : 84)	NC score	0.025206 (rank : 115)
Query Neighborhood Hits	175	Target Neighborhood Hits	212	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

PCLO_MOUSE
θ value	0.62314 (rank : 85)	NC score	0.046974 (rank : 70)
Query Neighborhood Hits	175	Target Neighborhood Hits	2275	Shared Neighborhood Hits	111
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

STA13_HUMAN
θ value	0.62314 (rank : 86)	NC score	0.018421 (rank : 129)
Query Neighborhood Hits	175	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

STA13_MOUSE
θ value	0.62314 (rank : 87)	NC score	0.018647 (rank : 128)
Query Neighborhood Hits	175	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

BPTF_HUMAN
θ value	0.813845 (rank : 88)	NC score	0.034519 (rank : 98)
Query Neighborhood Hits	175	Target Neighborhood Hits	786	Shared Neighborhood Hits	40
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

ENAH_HUMAN
θ value	0.813845 (rank : 89)	NC score	0.017960 (rank : 130)
Query Neighborhood Hits	175	Target Neighborhood Hits	784	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

EP300_HUMAN
θ value	0.813845 (rank : 90)	NC score	0.038692 (rank : 88)
Query Neighborhood Hits	175	Target Neighborhood Hits	821	Shared Neighborhood Hits	48
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

MORC2_HUMAN
θ value	0.813845 (rank : 91)	NC score	0.025263 (rank : 114)
Query Neighborhood Hits	175	Target Neighborhood Hits	207	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

PO2F2_MOUSE
θ value	0.813845 (rank : 92)	NC score	0.015136 (rank : 144)
Query Neighborhood Hits	175	Target Neighborhood Hits	353	Shared Neighborhood Hits	9
SwissProt Accessions	Q00196, Q00197, Q00198, Q00199, Q00200, Q00201, Q05882, Q61995, Q61996, Q64245	Gene names	Pou2f2, Oct2, Otf2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

RENBP_MOUSE
θ value	0.813845 (rank : 93)	NC score	0.031071 (rank : 104)
Query Neighborhood Hits	175	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P82343, Q80Z67, Q9CXI1	Gene names	Renbp
Domain Architecture
Description	N-acylglucosamine 2-epimerase (EC 5.1.3.8) (GlcNAc 2-epimerase) (N- acetyl-D-glucosamine 2-epimerase) (AGE) (Renin-binding protein) (RnBP).

SYNJ1_MOUSE
θ value	0.813845 (rank : 94)	NC score	0.028767 (rank : 108)
Query Neighborhood Hits	175	Target Neighborhood Hits	516	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

TF65_HUMAN
θ value	0.813845 (rank : 95)	NC score	0.024390 (rank : 116)
Query Neighborhood Hits	175	Target Neighborhood Hits	115	Shared Neighborhood Hits	19
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

ATBF1_HUMAN
θ value	1.06291 (rank : 96)	NC score	0.021285 (rank : 121)
Query Neighborhood Hits	175	Target Neighborhood Hits	1547	Shared Neighborhood Hits	37
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

LDB3_MOUSE
θ value	1.06291 (rank : 97)	NC score	0.017745 (rank : 132)
Query Neighborhood Hits	175	Target Neighborhood Hits	510	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

MUC2_HUMAN
θ value	1.06291 (rank : 98)	NC score	0.020508 (rank : 123)
Query Neighborhood Hits	175	Target Neighborhood Hits	906	Shared Neighborhood Hits	35
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

PO2F2_HUMAN
θ value	1.06291 (rank : 99)	NC score	0.016848 (rank : 134)
Query Neighborhood Hits	175	Target Neighborhood Hits	379	Shared Neighborhood Hits	15
SwissProt Accessions	P09086, Q16648, Q9BRS4	Gene names	POU2F2, OCT2, OTF2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

ROBO4_HUMAN
θ value	1.06291 (rank : 100)	NC score	0.011498 (rank : 152)
Query Neighborhood Hits	175	Target Neighborhood Hits	364	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

SMCA4_HUMAN
θ value	1.06291 (rank : 101)	NC score	0.023487 (rank : 118)
Query Neighborhood Hits	175	Target Neighborhood Hits	597	Shared Neighborhood Hits	28
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

WNK4_HUMAN
θ value	1.06291 (rank : 102)	NC score	0.009695 (rank : 162)
Query Neighborhood Hits	175	Target Neighborhood Hits	1043	Shared Neighborhood Hits	28
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

MOR2B_MOUSE
θ value	1.38821 (rank : 103)	NC score	0.021387 (rank : 120)
Query Neighborhood Hits	175	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C5W4, Q8CG24	Gene names	Morc2b, Tce6
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2B (TCE6).

NTBP1_MOUSE
θ value	1.38821 (rank : 104)	NC score	0.029364 (rank : 105)
Query Neighborhood Hits	175	Target Neighborhood Hits	528	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

ZXDA_HUMAN
θ value	1.38821 (rank : 105)	NC score	-0.001132 (rank : 189)
Query Neighborhood Hits	175	Target Neighborhood Hits	750	Shared Neighborhood Hits	12
SwissProt Accessions	P98168, Q9UJP7	Gene names	ZXDA
Domain Architecture	No domain graphic available
Description	Zinc finger X-linked protein ZXDA.

P85B_MOUSE
θ value	1.81305 (rank : 106)	NC score	0.046266 (rank : 75)
Query Neighborhood Hits	175	Target Neighborhood Hits	519	Shared Neighborhood Hits	31
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

RFX1_MOUSE
θ value	1.81305 (rank : 107)	NC score	0.016583 (rank : 137)
Query Neighborhood Hits	175	Target Neighborhood Hits	181	Shared Neighborhood Hits	13
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

SIN3A_HUMAN
θ value	1.81305 (rank : 108)	NC score	0.015850 (rank : 143)
Query Neighborhood Hits	175	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

STX4_HUMAN
θ value	1.81305 (rank : 109)	NC score	0.007992 (rank : 166)
Query Neighborhood Hits	175	Target Neighborhood Hits	266	Shared Neighborhood Hits	5
SwissProt Accessions	Q12846, Q15525	Gene names	STX4, STX4A
Domain Architecture
Description	Syntaxin-4 (NY-REN-31 antigen).

PO6F2_MOUSE
θ value	2.36792 (rank : 110)	NC score	0.015955 (rank : 142)
Query Neighborhood Hits	175	Target Neighborhood Hits	639	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

RERE_HUMAN
θ value	2.36792 (rank : 111)	NC score	0.025706 (rank : 113)
Query Neighborhood Hits	175	Target Neighborhood Hits	779	Shared Neighborhood Hits	39
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

SPR1B_MOUSE
θ value	2.36792 (rank : 112)	NC score	0.109244 (rank : 17)
Query Neighborhood Hits	175	Target Neighborhood Hits	395	Shared Neighborhood Hits	74
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

UTP20_HUMAN
θ value	2.36792 (rank : 113)	NC score	0.014066 (rank : 146)
Query Neighborhood Hits	175	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

DDEF1_MOUSE
θ value	3.0926 (rank : 114)	NC score	0.010214 (rank : 156)
Query Neighborhood Hits	175	Target Neighborhood Hits	592	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

EP400_MOUSE
θ value	3.0926 (rank : 115)	NC score	0.028783 (rank : 107)
Query Neighborhood Hits	175	Target Neighborhood Hits	592	Shared Neighborhood Hits	47
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

FGD1_MOUSE
θ value	3.0926 (rank : 116)	NC score	0.016619 (rank : 136)
Query Neighborhood Hits	175	Target Neighborhood Hits	387	Shared Neighborhood Hits	21
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

LAP4_HUMAN
θ value	3.0926 (rank : 117)	NC score	0.003250 (rank : 186)
Query Neighborhood Hits	175	Target Neighborhood Hits	608	Shared Neighborhood Hits	12
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

NRK_HUMAN
θ value	3.0926 (rank : 118)	NC score	0.003573 (rank : 185)
Query Neighborhood Hits	175	Target Neighborhood Hits	931	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

RGDSR_HUMAN
θ value	3.0926 (rank : 119)	NC score	0.059728 (rank : 50)
Query Neighborhood Hits	175	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZJ4	Gene names	RGR
Domain Architecture
Description	Ral-GDS-related protein (hRGR).

SHAN1_HUMAN
θ value	3.0926 (rank : 120)	NC score	0.009744 (rank : 160)
Query Neighborhood Hits	175	Target Neighborhood Hits	1041	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

AAK1_HUMAN
θ value	4.03905 (rank : 121)	NC score	0.010021 (rank : 157)
Query Neighborhood Hits	175	Target Neighborhood Hits	1077	Shared Neighborhood Hits	56
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

ETV5_HUMAN
θ value	4.03905 (rank : 122)	NC score	0.011854 (rank : 149)
Query Neighborhood Hits	175	Target Neighborhood Hits	181	Shared Neighborhood Hits	24
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

IRX3_HUMAN
θ value	4.03905 (rank : 123)	NC score	0.011692 (rank : 150)
Query Neighborhood Hits	175	Target Neighborhood Hits	342	Shared Neighborhood Hits	13
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

MYH8_HUMAN
θ value	4.03905 (rank : 124)	NC score	0.005653 (rank : 179)
Query Neighborhood Hits	175	Target Neighborhood Hits	1610	Shared Neighborhood Hits	37
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH8_MOUSE
θ value	4.03905 (rank : 125)	NC score	0.004099 (rank : 183)
Query Neighborhood Hits	175	Target Neighborhood Hits	1600	Shared Neighborhood Hits	31
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NOL3_MOUSE
θ value	4.03905 (rank : 126)	NC score	0.031862 (rank : 101)
Query Neighborhood Hits	175	Target Neighborhood Hits	97	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

P55G_MOUSE
θ value	4.03905 (rank : 127)	NC score	0.050539 (rank : 65)
Query Neighborhood Hits	175	Target Neighborhood Hits	401	Shared Neighborhood Hits	30
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P85B_HUMAN
θ value	4.03905 (rank : 128)	NC score	0.046885 (rank : 71)
Query Neighborhood Hits	175	Target Neighborhood Hits	543	Shared Neighborhood Hits	35
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

YTHD3_HUMAN
θ value	4.03905 (rank : 129)	NC score	0.014060 (rank : 147)
Query Neighborhood Hits	175	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z739, Q63Z37, Q659A3	Gene names	YTHDF3
Domain Architecture	No domain graphic available
Description	YTH domain family protein 3.

ZCHC7_HUMAN
θ value	4.03905 (rank : 130)	NC score	0.031294 (rank : 103)
Query Neighborhood Hits	175	Target Neighborhood Hits	73	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N3Z6, Q5T0Q8, Q5T0Q9, Q5T0R0, Q8N2M1, Q8N4J2, Q8TBK8, Q9H648, Q9P0F0	Gene names	ZCCHC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 7.

CCNB1_MOUSE
θ value	5.27518 (rank : 131)	NC score	0.005842 (rank : 177)
Query Neighborhood Hits	175	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	P24860	Gene names	Ccnb1, Ccn-2, Ccnb1-rs13, Cycb, Cycb1
Domain Architecture
Description	G2/mitotic-specific cyclin-B1.

FYN_HUMAN
θ value	5.27518 (rank : 132)	NC score	0.005869 (rank : 176)
Query Neighborhood Hits	175	Target Neighborhood Hits	1078	Shared Neighborhood Hits	28
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

G3BP_HUMAN
θ value	5.27518 (rank : 133)	NC score	0.017312 (rank : 133)
Query Neighborhood Hits	175	Target Neighborhood Hits	219	Shared Neighborhood Hits	8
SwissProt Accessions	Q13283	Gene names	G3BP, G3BP1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

GPR64_HUMAN
θ value	5.27518 (rank : 134)	NC score	0.007608 (rank : 168)
Query Neighborhood Hits	175	Target Neighborhood Hits	207	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

KLF11_HUMAN
θ value	5.27518 (rank : 135)	NC score	-0.001221 (rank : 190)
Query Neighborhood Hits	175	Target Neighborhood Hits	717	Shared Neighborhood Hits	10
SwissProt Accessions	O14901	Gene names	KLF11, FKLF, TIEG2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2).

KSR2_HUMAN
θ value	5.27518 (rank : 136)	NC score	0.005482 (rank : 180)
Query Neighborhood Hits	175	Target Neighborhood Hits	920	Shared Neighborhood Hits	21
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

M3K14_HUMAN
θ value	5.27518 (rank : 137)	NC score	0.003573 (rank : 184)
Query Neighborhood Hits	175	Target Neighborhood Hits	887	Shared Neighborhood Hits	25
SwissProt Accessions	Q99558, Q8IYN1	Gene names	MAP3K14, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) (HsNIK).

MKL2_MOUSE
θ value	5.27518 (rank : 138)	NC score	0.010008 (rank : 158)
Query Neighborhood Hits	175	Target Neighborhood Hits	269	Shared Neighborhood Hits	16
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

NACAM_MOUSE
θ value	5.27518 (rank : 139)	NC score	0.080128 (rank : 28)
Query Neighborhood Hits	175	Target Neighborhood Hits	1866	Shared Neighborhood Hits	109
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NCKX1_HUMAN
θ value	5.27518 (rank : 140)	NC score	0.013339 (rank : 148)
Query Neighborhood Hits	175	Target Neighborhood Hits	223	Shared Neighborhood Hits	7
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

P85A_HUMAN
θ value	5.27518 (rank : 141)	NC score	0.041951 (rank : 80)
Query Neighborhood Hits	175	Target Neighborhood Hits	479	Shared Neighborhood Hits	28
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

PAF49_HUMAN
θ value	5.27518 (rank : 142)	NC score	0.034936 (rank : 97)
Query Neighborhood Hits	175	Target Neighborhood Hits	169	Shared Neighborhood Hits	20
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

PO6F2_HUMAN
θ value	5.27518 (rank : 143)	NC score	0.014751 (rank : 145)
Query Neighborhood Hits	175	Target Neighborhood Hits	618	Shared Neighborhood Hits	22
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

SPEG_HUMAN
θ value	5.27518 (rank : 144)	NC score	0.004756 (rank : 182)
Query Neighborhood Hits	175	Target Neighborhood Hits	1762	Shared Neighborhood Hits	52
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

T22D2_HUMAN
θ value	5.27518 (rank : 145)	NC score	0.025744 (rank : 112)
Query Neighborhood Hits	175	Target Neighborhood Hits	250	Shared Neighborhood Hits	20
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

TSH3_MOUSE
θ value	5.27518 (rank : 146)	NC score	0.005752 (rank : 178)
Query Neighborhood Hits	175	Target Neighborhood Hits	590	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

YTHD3_MOUSE
θ value	5.27518 (rank : 147)	NC score	0.016402 (rank : 139)
Query Neighborhood Hits	175	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BYK6, Q3UVI5, Q6NXJ6, Q6NXJ8, Q8BKB6	Gene names	Ythdf3
Domain Architecture	No domain graphic available
Description	YTH domain family protein 3.

EP400_HUMAN
θ value	6.88961 (rank : 148)	NC score	0.026562 (rank : 110)
Query Neighborhood Hits	175	Target Neighborhood Hits	556	Shared Neighborhood Hits	33
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

FGR_HUMAN
θ value	6.88961 (rank : 149)	NC score	0.006406 (rank : 172)
Query Neighborhood Hits	175	Target Neighborhood Hits	1067	Shared Neighborhood Hits	29
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FGR_MOUSE
θ value	6.88961 (rank : 150)	NC score	0.006493 (rank : 171)
Query Neighborhood Hits	175	Target Neighborhood Hits	1069	Shared Neighborhood Hits	28
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FYN_MOUSE
θ value	6.88961 (rank : 151)	NC score	0.006293 (rank : 173)
Query Neighborhood Hits	175	Target Neighborhood Hits	1073	Shared Neighborhood Hits	30
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

GSCR1_HUMAN
θ value	6.88961 (rank : 152)	NC score	0.032612 (rank : 99)
Query Neighborhood Hits	175	Target Neighborhood Hits	674	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

K0460_MOUSE
θ value	6.88961 (rank : 153)	NC score	0.017800 (rank : 131)
Query Neighborhood Hits	175	Target Neighborhood Hits	374	Shared Neighborhood Hits	24
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

KLF11_MOUSE
θ value	6.88961 (rank : 154)	NC score	-0.001430 (rank : 191)
Query Neighborhood Hits	175	Target Neighborhood Hits	714	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EPF4	Gene names	Klf11, Tieg2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2).

MRCKA_HUMAN
θ value	6.88961 (rank : 155)	NC score	0.002678 (rank : 187)
Query Neighborhood Hits	175	Target Neighborhood Hits	1999	Shared Neighborhood Hits	49
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

P55G_HUMAN
θ value	6.88961 (rank : 156)	NC score	0.042695 (rank : 79)
Query Neighborhood Hits	175	Target Neighborhood Hits	451	Shared Neighborhood Hits	28
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P85A_MOUSE
θ value	6.88961 (rank : 157)	NC score	0.040186 (rank : 85)
Query Neighborhood Hits	175	Target Neighborhood Hits	435	Shared Neighborhood Hits	27
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

PTN23_HUMAN
θ value	6.88961 (rank : 158)	NC score	0.021528 (rank : 119)
Query Neighborhood Hits	175	Target Neighborhood Hits	646	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SH22A_HUMAN
θ value	6.88961 (rank : 159)	NC score	0.091370 (rank : 27)
Query Neighborhood Hits	175	Target Neighborhood Hits	144	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

SSH1_HUMAN
θ value	6.88961 (rank : 160)	NC score	0.005155 (rank : 181)
Query Neighborhood Hits	175	Target Neighborhood Hits	164	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

TBC10_HUMAN
θ value	6.88961 (rank : 161)	NC score	0.006207 (rank : 175)
Query Neighborhood Hits	175	Target Neighborhood Hits	64	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXI6, O76053, Q543A2	Gene names	TBC1D10A, EPI64, TBC1D10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

TMLH_HUMAN
θ value	6.88961 (rank : 162)	NC score	0.008857 (rank : 163)
Query Neighborhood Hits	175	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NVH6	Gene names	TMLHE, TMLH
Domain Architecture
Description	Trimethyllysine dioxygenase, mitochondrial precursor (EC 1.14.11.8) (Epsilon-trimethyllysine 2-oxoglutarate dioxygenase) (TML-alpha- ketoglutarate dioxygenase) (TML hydroxylase) (TML dioxygenase) (TMLD).

TREF1_MOUSE
θ value	6.88961 (rank : 163)	NC score	0.007230 (rank : 169)
Query Neighborhood Hits	175	Target Neighborhood Hits	682	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

VPS28_HUMAN
θ value	6.88961 (rank : 164)	NC score	0.016200 (rank : 140)
Query Neighborhood Hits	175	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UK41	Gene names	VPS28
Domain Architecture
Description	Vacuolar protein sorting-associated protein 28 homolog.

VPS28_MOUSE
θ value	6.88961 (rank : 165)	NC score	0.016115 (rank : 141)
Query Neighborhood Hits	175	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D1C8	Gene names	Vps28
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 28 homolog (Caspase- activated DNase inhibitor that interacts with ASK1) (CIIA).

WBP11_MOUSE
θ value	6.88961 (rank : 166)	NC score	0.020055 (rank : 126)
Query Neighborhood Hits	175	Target Neighborhood Hits	362	Shared Neighborhood Hits	20
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

WNK4_MOUSE
θ value	6.88961 (rank : 167)	NC score	0.008482 (rank : 164)
Query Neighborhood Hits	175	Target Neighborhood Hits	961	Shared Neighborhood Hits	25
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ZN207_HUMAN
θ value	6.88961 (rank : 168)	NC score	0.031653 (rank : 102)
Query Neighborhood Hits	175	Target Neighborhood Hits	326	Shared Neighborhood Hits	18
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

CRF_HUMAN
θ value	8.99809 (rank : 169)	NC score	0.010984 (rank : 154)
Query Neighborhood Hits	175	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	P06850	Gene names	CRH
Domain Architecture
Description	Corticoliberin precursor (Corticotropin-releasing factor) (CRF) (Corticotropin-releasing hormone).

G3PT_HUMAN
θ value	8.99809 (rank : 170)	NC score	0.006740 (rank : 170)
Query Neighborhood Hits	175	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	O14556, O60823, Q6JTT9, Q9HCU6	Gene names	GAPDHS, GAPD2, GAPDH2, GAPDS
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

P66B_MOUSE
θ value	8.99809 (rank : 171)	NC score	0.007659 (rank : 167)
Query Neighborhood Hits	175	Target Neighborhood Hits	64	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VHR5, Q8C9Q3	Gene names	Gatad2b
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 beta (p66/p68) (GATA zinc finger domain- containing protein 2B).

PI5PA_HUMAN
θ value	8.99809 (rank : 172)	NC score	0.034948 (rank : 96)
Query Neighborhood Hits	175	Target Neighborhood Hits	749	Shared Neighborhood Hits	65
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SH22A_MOUSE
θ value	8.99809 (rank : 173)	NC score	0.062963 (rank : 44)
Query Neighborhood Hits	175	Target Neighborhood Hits	179	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

TNC6B_HUMAN
θ value	8.99809 (rank : 174)	NC score	0.008210 (rank : 165)
Query Neighborhood Hits	175	Target Neighborhood Hits	256	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

WBS14_MOUSE
θ value	8.99809 (rank : 175)	NC score	0.020410 (rank : 124)
Query Neighborhood Hits	175	Target Neighborhood Hits	171	Shared Neighborhood Hits	17
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

CK024_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.059345 (rank : 52)
Query Neighborhood Hits	175	Target Neighborhood Hits	408	Shared Neighborhood Hits	56
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

FA47B_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.067258 (rank : 38)
Query Neighborhood Hits	175	Target Neighborhood Hits	431	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

K1683_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.054424 (rank : 61)
Query Neighborhood Hits	175	Target Neighborhood Hits	240	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

MDC1_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.076160 (rank : 33)
Query Neighborhood Hits	175	Target Neighborhood Hits	1446	Shared Neighborhood Hits	97
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.076187 (rank : 32)
Query Neighborhood Hits	175	Target Neighborhood Hits	998	Shared Neighborhood Hits	87
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MUC1_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.060307 (rank : 48)
Query Neighborhood Hits	175	Target Neighborhood Hits	975	Shared Neighborhood Hits	71
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

NCOA6_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.058296 (rank : 55)
Query Neighborhood Hits	175	Target Neighborhood Hits	1202	Shared Neighborhood Hits	96
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

OGFR_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.055618 (rank : 58)
Query Neighborhood Hits	175	Target Neighborhood Hits	1582	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

PRRT3_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.062225 (rank : 46)
Query Neighborhood Hits	175	Target Neighborhood Hits	998	Shared Neighborhood Hits	87
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RGS3_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.052179 (rank : 63)
Query Neighborhood Hits	175	Target Neighborhood Hits	1621	Shared Neighborhood Hits	102
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SELPL_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.065058 (rank : 42)
Query Neighborhood Hits	175	Target Neighborhood Hits	588	Shared Neighborhood Hits	68
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SPR1A_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.079264 (rank : 29)
Query Neighborhood Hits	175	Target Neighborhood Hits	343	Shared Neighborhood Hits	60
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

SPRR3_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.093547 (rank : 26)
Query Neighborhood Hits	175	Target Neighborhood Hits	102	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

SPRR3_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.062541 (rank : 45)
Query Neighborhood Hits	175	Target Neighborhood Hits	106	Shared Neighborhood Hits	23
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

TARSH_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.072264 (rank : 35)
Query Neighborhood Hits	175	Target Neighborhood Hits	768	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

TXND2_HUMAN
θ value	θ > 10 (rank : 191)	NC score	0.050412 (rank : 66)
Query Neighborhood Hits	175	Target Neighborhood Hits	793	Shared Neighborhood Hits	52
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

Hits sorted by NC score

STAT2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	175	Target Neighborhood Hits	175	Shared Neighborhood Hits	175
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

STAT2_HUMAN
NC score	0.945423 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	175	Target Neighborhood Hits	99	Shared Neighborhood Hits	31
SwissProt Accessions	P52630, Q16430, Q16431	Gene names	STAT2
Domain Architecture
Description	Signal transducer and activator of transcription 2 (p113).

STAT4_MOUSE
NC score	0.918194 (rank : 3)	θ value	1.29561e-123 (rank : 8)
Query Neighborhood Hits	175	Target Neighborhood Hits	73	Shared Neighborhood Hits	16
SwissProt Accessions	P42228	Gene names	Stat4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STAT4_HUMAN
NC score	0.915475 (rank : 4)	θ value	1.80368e-133 (rank : 5)
Query Neighborhood Hits	175	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	Q14765, Q96NZ6	Gene names	STAT4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STAT1_HUMAN
NC score	0.914295 (rank : 5)	θ value	2.77624e-142 (rank : 3)
Query Neighborhood Hits	175	Target Neighborhood Hits	128	Shared Neighborhood Hits	22
SwissProt Accessions	P42224	Gene names	STAT1
Domain Architecture
Description	Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84).

STAT1_MOUSE
NC score	0.913431 (rank : 6)	θ value	1.98959e-140 (rank : 4)
Query Neighborhood Hits	175	Target Neighborhood Hits	151	Shared Neighborhood Hits	25
SwissProt Accessions	P42225	Gene names	Stat1
Domain Architecture
Description	Signal transducer and activator of transcription 1.

STAT3_HUMAN
NC score	0.907802 (rank : 7)	θ value	2.20485e-131 (rank : 6)
Query Neighborhood Hits	175	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	P40763, O14916, Q9BW54	Gene names	STAT3, APRF
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT3_MOUSE
NC score	0.907801 (rank : 8)	θ value	2.20485e-131 (rank : 7)
Query Neighborhood Hits	175	Target Neighborhood Hits	155	Shared Neighborhood Hits	19
SwissProt Accessions	P42227	Gene names	Stat3, Aprf
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STA5B_HUMAN
NC score	0.821279 (rank : 9)	θ value	2.3352e-48 (rank : 9)
Query Neighborhood Hits	175	Target Neighborhood Hits	103	Shared Neighborhood Hits	23
SwissProt Accessions	P51692, Q8WWS8	Gene names	STAT5B
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STA5B_MOUSE
NC score	0.818896 (rank : 10)	θ value	6.7944e-48 (rank : 10)
Query Neighborhood Hits	175	Target Neighborhood Hits	124	Shared Neighborhood Hits	24
SwissProt Accessions	P42232, Q541Q5, Q60804, Q8K3Q1, Q9JKM1	Gene names	Stat5b
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STA5A_MOUSE
NC score	0.816370 (rank : 11)	θ value	7.51208e-47 (rank : 11)
Query Neighborhood Hits	175	Target Neighborhood Hits	128	Shared Neighborhood Hits	26
SwissProt Accessions	P42230	Gene names	Stat5a, Mgf, Mpf
Domain Architecture
Description	Signal transducer and activator of transcription 5A (Mammary gland factor).

STA5A_HUMAN
NC score	0.813506 (rank : 12)	θ value	2.18568e-46 (rank : 12)
Query Neighborhood Hits	175	Target Neighborhood Hits	140	Shared Neighborhood Hits	24
SwissProt Accessions	P42229	Gene names	STAT5A, STAT5
Domain Architecture
Description	Signal transducer and activator of transcription 5A.

STAT6_HUMAN
NC score	0.795069 (rank : 13)	θ value	4.00176e-32 (rank : 13)
Query Neighborhood Hits	175	Target Neighborhood Hits	132	Shared Neighborhood Hits	36
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

STAT6_MOUSE
NC score	0.793713 (rank : 14)	θ value	7.54701e-31 (rank : 14)
Query Neighborhood Hits	175	Target Neighborhood Hits	78	Shared Neighborhood Hits	28
SwissProt Accessions	P52633	Gene names	Stat6
Domain Architecture
Description	Signal transducer and transcription activator 6.

PRAX_HUMAN
NC score	0.120915 (rank : 15)	θ value	0.00869519 (rank : 38)
Query Neighborhood Hits	175	Target Neighborhood Hits	215	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BXM0, Q9BXL9, Q9HCF2	Gene names	PRX, KIAA1620
Domain Architecture
Description	Periaxin.

PRAX_MOUSE
NC score	0.113241 (rank : 16)	θ value	0.00298849 (rank : 32)
Query Neighborhood Hits	175	Target Neighborhood Hits	199	Shared Neighborhood Hits	29
SwissProt Accessions	O55103, O55104	Gene names	Prx
Domain Architecture
Description	Periaxin.

SPR1B_MOUSE
NC score	0.109244 (rank : 17)	θ value	2.36792 (rank : 112)
Query Neighborhood Hits	175	Target Neighborhood Hits	395	Shared Neighborhood Hits	74
SwissProt Accessions	Q62267	Gene names	Sprr1b
Domain Architecture
Description	Cornifin B (Small proline-rich protein 1B) (SPR1B) (SPR1 B).

SON_HUMAN
NC score	0.108404 (rank : 18)	θ value	0.00298849 (rank : 33)
Query Neighborhood Hits	175	Target Neighborhood Hits	1568	Shared Neighborhood Hits	111
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

CIZ1_HUMAN
NC score	0.107773 (rank : 19)	θ value	5.44631e-05 (rank : 20)
Query Neighborhood Hits	175	Target Neighborhood Hits	359	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

DGKK_HUMAN
NC score	0.105414 (rank : 20)	θ value	5.8054e-15 (rank : 15)
Query Neighborhood Hits	175	Target Neighborhood Hits	378	Shared Neighborhood Hits	27
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

GNDS_HUMAN
NC score	0.102960 (rank : 21)	θ value	1.80886e-08 (rank : 19)
Query Neighborhood Hits	175	Target Neighborhood Hits	201	Shared Neighborhood Hits	22
SwissProt Accessions	Q12967, Q9HAX7, Q9HAY1, Q9HCT1	Gene names	RALGDS, RGF
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

PRG4_HUMAN
NC score	0.102707 (rank : 22)	θ value	3.52202e-12 (rank : 16)
Query Neighborhood Hits	175	Target Neighborhood Hits	764	Shared Neighborhood Hits	34
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

GNDS_MOUSE
NC score	0.101772 (rank : 23)	θ value	1.06045e-08 (rank : 17)
Query Neighborhood Hits	175	Target Neighborhood Hits	115	Shared Neighborhood Hits	10
SwissProt Accessions	Q03385	Gene names	Ralgds, Rgds
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator (RalGEF) (RalGDS).

PRG4_MOUSE
NC score	0.101343 (rank : 24)	θ value	1.06045e-08 (rank : 18)
Query Neighborhood Hits	175	Target Neighborhood Hits	624	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SON_MOUSE
NC score	0.096439 (rank : 25)	θ value	0.0252991 (rank : 42)
Query Neighborhood Hits	175	Target Neighborhood Hits	957	Shared Neighborhood Hits	77
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

SPRR3_HUMAN
NC score	0.093547 (rank : 26)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	175	Target Neighborhood Hits	102	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UBC9, O75597, Q4ZGI7, Q5T525, Q8NET7, Q9UDG3	Gene names	SPRR3, SPRC
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta) (Esophagin) (22 kDa pancornulin).

SH22A_HUMAN
NC score	0.091370 (rank : 27)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	175	Target Neighborhood Hits	144	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

NACAM_MOUSE
NC score	0.080128 (rank : 28)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	175	Target Neighborhood Hits	1866	Shared Neighborhood Hits	109
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SPR1A_MOUSE
NC score	0.079264 (rank : 29)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	175	Target Neighborhood Hits	343	Shared Neighborhood Hits	60
SwissProt Accessions	Q62266	Gene names	Sprr1a
Domain Architecture	No domain graphic available
Description	Cornifin A (Small proline-rich protein 1A) (SPR1A) (SPR1 A).

CDN1C_HUMAN
NC score	0.079005 (rank : 30)	θ value	0.000786445 (rank : 26)
Query Neighborhood Hits	175	Target Neighborhood Hits	168	Shared Neighborhood Hits	16
SwissProt Accessions	P49918	Gene names	CDKN1C, KIP2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

PHLA1_MOUSE
NC score	0.077292 (rank : 31)	θ value	0.00298849 (rank : 31)
Query Neighborhood Hits	175	Target Neighborhood Hits	103	Shared Neighborhood Hits	13
SwissProt Accessions	Q62392, Q3TY48, Q3UG87	Gene names	Phlda1, Tdag51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Proline- and glutamine-rich protein) (PQR protein).

MDC1_MOUSE
NC score	0.076187 (rank : 32)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	175	Target Neighborhood Hits	998	Shared Neighborhood Hits	87
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MDC1_HUMAN
NC score	0.076160 (rank : 33)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	175	Target Neighborhood Hits	1446	Shared Neighborhood Hits	97
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PHLA1_HUMAN
NC score	0.074677 (rank : 34)	θ value	0.0193708 (rank : 41)
Query Neighborhood Hits	175	Target Neighborhood Hits	121	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WV24, Q15184, Q2TAN2, Q9NZ17	Gene names	PHLDA1, PHRIP, TDAG51
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family A member 1 (T-cell death- associated gene 51 protein) (Apoptosis-associated nuclear protein) (Proline- and histidine-rich protein) (Proline- and glutamine-rich protein) (PQ-rich protein).

TARSH_HUMAN
NC score	0.072264 (rank : 35)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	175	Target Neighborhood Hits	768	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

AUTS2_HUMAN
NC score	0.071009 (rank : 36)	θ value	0.0193708 (rank : 40)
Query Neighborhood Hits	175	Target Neighborhood Hits	342	Shared Neighborhood Hits	36
SwissProt Accessions	Q8WXX7, Q9Y4F2	Gene names	AUTS2, KIAA0442
Domain Architecture	No domain graphic available
Description	Autism susceptibility gene 2 protein.

MNT_HUMAN
NC score	0.067535 (rank : 37)	θ value	0.0431538 (rank : 46)
Query Neighborhood Hits	175	Target Neighborhood Hits	496	Shared Neighborhood Hits	46
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

FA47B_HUMAN
NC score	0.067258 (rank : 38)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	175	Target Neighborhood Hits	431	Shared Neighborhood Hits	59
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

SRBP1_MOUSE
NC score	0.066933 (rank : 39)	θ value	0.000602161 (rank : 25)
Query Neighborhood Hits	175	Target Neighborhood Hits	384	Shared Neighborhood Hits	47
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

MNT_MOUSE
NC score	0.065688 (rank : 40)	θ value	0.00869519 (rank : 37)
Query Neighborhood Hits	175	Target Neighborhood Hits	432	Shared Neighborhood Hits	34
SwissProt Accessions	O08789, P97349	Gene names	Mnt, Rox
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

SELV_HUMAN
NC score	0.065162 (rank : 41)	θ value	0.0330416 (rank : 45)
Query Neighborhood Hits	175	Target Neighborhood Hits	118	Shared Neighborhood Hits	12
SwissProt Accessions	P59797	Gene names	SELV
Domain Architecture	No domain graphic available
Description	Selenoprotein V.

SELPL_MOUSE
NC score	0.065058 (rank : 42)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	175	Target Neighborhood Hits	588	Shared Neighborhood Hits	68
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

CDN1C_MOUSE
NC score	0.063529 (rank : 43)	θ value	0.279714 (rank : 68)
Query Neighborhood Hits	175	Target Neighborhood Hits	161	Shared Neighborhood Hits	11
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

SH22A_MOUSE
NC score	0.062963 (rank : 44)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	175	Target Neighborhood Hits	179	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

SPRR3_MOUSE
NC score	0.062541 (rank : 45)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	175	Target Neighborhood Hits	106	Shared Neighborhood Hits	23
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

PRRT3_HUMAN
NC score	0.062225 (rank : 46)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	175	Target Neighborhood Hits	998	Shared Neighborhood Hits	87
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

TAF4_HUMAN
NC score	0.062209 (rank : 47)	θ value	0.00390308 (rank : 34)
Query Neighborhood Hits	175	Target Neighborhood Hits	687	Shared Neighborhood Hits	42
SwissProt Accessions	O00268, Q5TBP6, Q99721, Q9BR40, Q9BX42	Gene names	TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135
Domain Architecture
Description	Transcription initiation factor TFIID subunit 4 (TBP-associated factor 4) (Transcription initiation factor TFIID 135 kDa subunit) (TAF(II)135) (TAFII-135) (TAFII135) (TAFII-130) (TAFII130).

MUC1_HUMAN
NC score	0.060307 (rank : 48)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	175	Target Neighborhood Hits	975	Shared Neighborhood Hits	71
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

PININ_MOUSE
NC score	0.060073 (rank : 49)	θ value	0.000602161 (rank : 24)
Query Neighborhood Hits	175	Target Neighborhood Hits	777	Shared Neighborhood Hits	23
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

RGDSR_HUMAN
NC score	0.059728 (rank : 50)	θ value	3.0926 (rank : 119)
Query Neighborhood Hits	175	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IZJ4	Gene names	RGR
Domain Architecture
Description	Ral-GDS-related protein (hRGR).

SF3A1_MOUSE
NC score	0.059634 (rank : 51)	θ value	0.0563607 (rank : 47)
Query Neighborhood Hits	175	Target Neighborhood Hits	198	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

CK024_HUMAN
NC score	0.059345 (rank : 52)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	175	Target Neighborhood Hits	408	Shared Neighborhood Hits	56
SwissProt Accessions	Q96F05, Q9H2K4	Gene names	C11orf24
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C11orf24 precursor (Protein DM4E3).

SF3A1_HUMAN
NC score	0.059081 (rank : 53)	θ value	0.0736092 (rank : 53)
Query Neighborhood Hits	175	Target Neighborhood Hits	199	Shared Neighborhood Hits	14
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

MOT8_MOUSE
NC score	0.058825 (rank : 54)	θ value	0.00134147 (rank : 27)
Query Neighborhood Hits	175	Target Neighborhood Hits	96	Shared Neighborhood Hits	12
SwissProt Accessions	O70324, Q8K3S9	Gene names	Slc16a2, Mct8, Xpct
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

NCOA6_HUMAN
NC score	0.058296 (rank : 55)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	175	Target Neighborhood Hits	1202	Shared Neighborhood Hits	96
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

PININ_HUMAN
NC score	0.057242 (rank : 56)	θ value	0.000158464 (rank : 21)
Query Neighborhood Hits	175	Target Neighborhood Hits	753	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

IASPP_MOUSE
NC score	0.055834 (rank : 57)	θ value	0.00175202 (rank : 28)
Query Neighborhood Hits	175	Target Neighborhood Hits	1024	Shared Neighborhood Hits	60
SwissProt Accessions	Q5I1X5	Gene names	Ppp1r13l, Nkip1
Domain Architecture	No domain graphic available
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

OGFR_HUMAN
NC score	0.055618 (rank : 58)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	175	Target Neighborhood Hits	1582	Shared Neighborhood Hits	90
SwissProt Accessions	Q9NZT2, O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5, Q9NZT3, Q9NZT4	Gene names	OGFR
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor) (7-60 protein).

MLL2_HUMAN
NC score	0.054709 (rank : 59)	θ value	0.163984 (rank : 61)
Query Neighborhood Hits	175	Target Neighborhood Hits	1788	Shared Neighborhood Hits	81
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

PHC3_MOUSE
NC score	0.054534 (rank : 60)	θ value	0.0330416 (rank : 44)
Query Neighborhood Hits	175	Target Neighborhood Hits	194	Shared Neighborhood Hits	21
SwissProt Accessions	Q8CHP6, Q3TLV5	Gene names	Phc3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3.

K1683_HUMAN
NC score	0.054424 (rank : 61)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	175	Target Neighborhood Hits	240	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

CASB_HUMAN
NC score	0.053405 (rank : 62)	θ value	0.365318 (rank : 74)
Query Neighborhood Hits	175	Target Neighborhood Hits	19	Shared Neighborhood Hits	6
SwissProt Accessions	P05814, Q4VAZ9	Gene names	CSN2, CASB
Domain Architecture	No domain graphic available
Description	Beta-casein precursor.

RGS3_MOUSE
NC score	0.052179 (rank : 63)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	175	Target Neighborhood Hits	1621	Shared Neighborhood Hits	102
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

PRR12_HUMAN
NC score	0.050754 (rank : 64)	θ value	0.365318 (rank : 79)
Query Neighborhood Hits	175	Target Neighborhood Hits	460	Shared Neighborhood Hits	35
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

P55G_MOUSE
NC score	0.050539 (rank : 65)	θ value	4.03905 (rank : 127)
Query Neighborhood Hits	175	Target Neighborhood Hits	401	Shared Neighborhood Hits	30
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

TXND2_HUMAN
NC score	0.050412 (rank : 66)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	175	Target Neighborhood Hits	793	Shared Neighborhood Hits	52
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

PHC3_HUMAN
NC score	0.049990 (rank : 67)	θ value	0.21417 (rank : 64)
Query Neighborhood Hits	175	Target Neighborhood Hits	218	Shared Neighborhood Hits	20
SwissProt Accessions	Q8NDX5, Q5HYF0, Q6NSG2, Q8NFT7, Q8NFZ1, Q8TBM2, Q9H971, Q9H9I4	Gene names	PHC3, EDR3, PH3
Domain Architecture	No domain graphic available
Description	Polyhomeotic-like protein 3 (hPH3) (Homolog of polyhomeotic 3) (Early development regulatory protein 3).

GP152_HUMAN
NC score	0.049629 (rank : 68)	θ value	0.365318 (rank : 76)
Query Neighborhood Hits	175	Target Neighborhood Hits	636	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDT2, Q86SM0	Gene names	GPR152, PGR5
Domain Architecture
Description	Probable G-protein coupled receptor 152 (G-protein coupled receptor PGR5).

IF4G1_MOUSE
NC score	0.048816 (rank : 69)	θ value	0.365318 (rank : 77)
Query Neighborhood Hits	175	Target Neighborhood Hits	534	Shared Neighborhood Hits	58
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

PCLO_MOUSE
NC score	0.046974 (rank : 70)	θ value	0.62314 (rank : 85)
Query Neighborhood Hits	175	Target Neighborhood Hits	2275	Shared Neighborhood Hits	111
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

P85B_HUMAN
NC score	0.046885 (rank : 71)	θ value	4.03905 (rank : 128)
Query Neighborhood Hits	175	Target Neighborhood Hits	543	Shared Neighborhood Hits	35
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

TACC3_MOUSE
NC score	0.046853 (rank : 72)	θ value	0.000158464 (rank : 22)
Query Neighborhood Hits	175	Target Neighborhood Hits	607	Shared Neighborhood Hits	22
SwissProt Accessions	Q9JJ11, Q9WVK9	Gene names	Tacc3, Aint
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ARNT-interacting protein).

CN155_HUMAN
NC score	0.046845 (rank : 73)	θ value	0.163984 (rank : 60)
Query Neighborhood Hits	175	Target Neighborhood Hits	385	Shared Neighborhood Hits	19
SwissProt Accessions	Q5H9T9, Q5H9U7, Q86YI2, Q9H0J3	Gene names	C14orf155
Domain Architecture	No domain graphic available
Description	Protein C14orf155.

IASPP_HUMAN
NC score	0.046412 (rank : 74)	θ value	0.00298849 (rank : 30)
Query Neighborhood Hits	175	Target Neighborhood Hits	688	Shared Neighborhood Hits	33
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

P85B_MOUSE
NC score	0.046266 (rank : 75)	θ value	1.81305 (rank : 106)
Query Neighborhood Hits	175	Target Neighborhood Hits	519	Shared Neighborhood Hits	31
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

CCAR1_HUMAN
NC score	0.045315 (rank : 76)	θ value	0.00665767 (rank : 35)
Query Neighborhood Hits	175	Target Neighborhood Hits	444	Shared Neighborhood Hits	16
SwissProt Accessions	Q8IX12, Q32NE3, Q5VUP6, Q6PIZ0, Q6X935, Q9H8N4, Q9NVA7, Q9NVQ0, Q9NWM6	Gene names	CCAR1, CARP1, DIS
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain).

GGN_MOUSE
NC score	0.044071 (rank : 77)	θ value	0.0736092 (rank : 52)
Query Neighborhood Hits	175	Target Neighborhood Hits	311	Shared Neighborhood Hits	20
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

BRD4_HUMAN
NC score	0.043879 (rank : 78)	θ value	0.0736092 (rank : 51)
Query Neighborhood Hits	175	Target Neighborhood Hits	851	Shared Neighborhood Hits	49
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

P55G_HUMAN
NC score	0.042695 (rank : 79)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	175	Target Neighborhood Hits	451	Shared Neighborhood Hits	28
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P85A_HUMAN
NC score	0.041951 (rank : 80)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	175	Target Neighborhood Hits	479	Shared Neighborhood Hits	28
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

RAPH1_HUMAN
NC score	0.041596 (rank : 81)	θ value	0.0961366 (rank : 58)
Query Neighborhood Hits	175	Target Neighborhood Hits	593	Shared Neighborhood Hits	36
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

WASF1_HUMAN
NC score	0.041524 (rank : 82)	θ value	0.0736092 (rank : 54)
Query Neighborhood Hits	175	Target Neighborhood Hits	260	Shared Neighborhood Hits	18
SwissProt Accessions	Q92558	Gene names	WASF1, KIAA0269, SCAR1, WAVE1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1) (Verprolin homology domain-containing protein 1).

MOT8_HUMAN
NC score	0.041384 (rank : 83)	θ value	0.279714 (rank : 72)
Query Neighborhood Hits	175	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	P36021, Q7Z797	Gene names	SLC16A2, MCT8, XPCT
Domain Architecture	No domain graphic available
Description	Monocarboxylate transporter 8 (MCT 8) (MCT 7) (Solute carrier family 16 member 2) (X-linked PEST-containing transporter).

WASF1_MOUSE
NC score	0.040415 (rank : 84)	θ value	0.0563607 (rank : 49)
Query Neighborhood Hits	175	Target Neighborhood Hits	261	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R5H6, Q91W51, Q9ERQ9	Gene names	Wasf1, Wave1
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein family member 1 (WASP-family protein member 1) (Protein WAVE-1).

P85A_MOUSE
NC score	0.040186 (rank : 85)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	175	Target Neighborhood Hits	435	Shared Neighborhood Hits	27
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

CI079_HUMAN
NC score	0.039989 (rank : 86)	θ value	0.47712 (rank : 80)
Query Neighborhood Hits	175	Target Neighborhood Hits	288	Shared Neighborhood Hits	23
SwissProt Accessions	Q6ZUB1, Q5SQC9, Q8NA41, Q8ND27	Gene names	C9orf79
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf79.

PHC1_HUMAN
NC score	0.039031 (rank : 87)	θ value	0.47712 (rank : 83)
Query Neighborhood Hits	175	Target Neighborhood Hits	227	Shared Neighborhood Hits	21
SwissProt Accessions	P78364, Q8WVM3, Q9BU63	Gene names	PHC1, EDR1, PH1
Domain Architecture
Description	Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1).

EP300_HUMAN
NC score	0.038692 (rank : 88)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	175	Target Neighborhood Hits	821	Shared Neighborhood Hits	48
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

SOX30_HUMAN
NC score	0.038558 (rank : 89)	θ value	0.0563607 (rank : 48)
Query Neighborhood Hits	175	Target Neighborhood Hits	305	Shared Neighborhood Hits	39
SwissProt Accessions	O94993, O94995, Q8IYX6	Gene names	SOX30
Domain Architecture
Description	Transcription factor SOX-30.

NTBP1_HUMAN
NC score	0.038522 (rank : 90)	θ value	0.365318 (rank : 78)
Query Neighborhood Hits	175	Target Neighborhood Hits	171	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T7V8, Q49A22, Q6P1P9, Q9HAE6, Q9Y350	Gene names	SCYL1BP1, NTKLBP1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (hNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

PTN23_MOUSE
NC score	0.038518 (rank : 91)	θ value	0.00035302 (rank : 23)
Query Neighborhood Hits	175	Target Neighborhood Hits	726	Shared Neighborhood Hits	48
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

CCAR1_MOUSE
NC score	0.037658 (rank : 92)	θ value	0.279714 (rank : 67)
Query Neighborhood Hits	175	Target Neighborhood Hits	414	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CH18, Q6AXC9, Q6PAR2, Q80XE4, Q8BJY0, Q8BVN2, Q8CGG1, Q9CSR5	Gene names	Ccar1, Carp1
Domain Architecture	No domain graphic available
Description	Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1).

BRD4_MOUSE
NC score	0.037653 (rank : 93)	θ value	0.279714 (rank : 66)
Query Neighborhood Hits	175	Target Neighborhood Hits	845	Shared Neighborhood Hits	37
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

3BP2_MOUSE
NC score	0.037393 (rank : 94)	θ value	0.163984 (rank : 59)
Query Neighborhood Hits	175	Target Neighborhood Hits	142	Shared Neighborhood Hits	20
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

GP152_MOUSE
NC score	0.037030 (rank : 95)	θ value	0.279714 (rank : 69)
Query Neighborhood Hits	175	Target Neighborhood Hits	607	Shared Neighborhood Hits	44
SwissProt Accessions	Q8BXS7	Gene names	Gpr152
Domain Architecture
Description	Probable G-protein coupled receptor 152.

PI5PA_HUMAN
NC score	0.034948 (rank : 96)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	175	Target Neighborhood Hits	749	Shared Neighborhood Hits	65
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PAF49_HUMAN
NC score	0.034936 (rank : 97)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	175	Target Neighborhood Hits	169	Shared Neighborhood Hits	20
SwissProt Accessions	O15446, Q32N11, Q7Z5U2, Q9UPF6	Gene names	CD3EAP, ASE1, CAST, PAF49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (CAST).

BPTF_HUMAN
NC score	0.034519 (rank : 98)	θ value	0.813845 (rank : 88)
Query Neighborhood Hits	175	Target Neighborhood Hits	786	Shared Neighborhood Hits	40
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

GSCR1_HUMAN
NC score	0.032612 (rank : 99)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	175	Target Neighborhood Hits	674	Shared Neighborhood Hits	45
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

MLL4_HUMAN
NC score	0.032429 (rank : 100)	θ value	0.279714 (rank : 71)
Query Neighborhood Hits	175	Target Neighborhood Hits	722	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

NOL3_MOUSE
NC score	0.031862 (rank : 101)	θ value	4.03905 (rank : 126)
Query Neighborhood Hits	175	Target Neighborhood Hits	97	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D1X0	Gene names	Nol3
Domain Architecture
Description	Nucleolar protein 3.

ZN207_HUMAN
NC score	0.031653 (rank : 102)	θ value	6.88961 (rank : 168)
Query Neighborhood Hits	175	Target Neighborhood Hits	326	Shared Neighborhood Hits	18
SwissProt Accessions	O43670, Q96HW5, Q9BUQ7	Gene names	ZNF207
Domain Architecture	No domain graphic available
Description	Zinc finger protein 207.

ZCHC7_HUMAN
NC score	0.031294 (rank : 103)	θ value	4.03905 (rank : 130)
Query Neighborhood Hits	175	Target Neighborhood Hits	73	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N3Z6, Q5T0Q8, Q5T0Q9, Q5T0R0, Q8N2M1, Q8N4J2, Q8TBK8, Q9H648, Q9P0F0	Gene names	ZCCHC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 7.

RENBP_MOUSE
NC score	0.031071 (rank : 104)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	175	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P82343, Q80Z67, Q9CXI1	Gene names	Renbp
Domain Architecture
Description	N-acylglucosamine 2-epimerase (EC 5.1.3.8) (GlcNAc 2-epimerase) (N- acetyl-D-glucosamine 2-epimerase) (AGE) (Renin-binding protein) (RnBP).

NTBP1_MOUSE
NC score	0.029364 (rank : 105)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	175	Target Neighborhood Hits	528	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BRM2, Q8CAA8	Gene names	Scyl1bp1, Ntklbp1
Domain Architecture	No domain graphic available
Description	N-terminal kinase-like-binding protein 1 (NTKL-binding protein 1) (NTKL-BP1) (mNTKL-BP1) (SCY1-like 1-binding protein 1) (SCYL1-binding protein 1) (SCYL1-BP1).

SMCA2_HUMAN
NC score	0.028870 (rank : 106)	θ value	0.00869519 (rank : 39)
Query Neighborhood Hits	175	Target Neighborhood Hits	503	Shared Neighborhood Hits	25
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

EP400_MOUSE
NC score	0.028783 (rank : 107)	θ value	3.0926 (rank : 115)
Query Neighborhood Hits	175	Target Neighborhood Hits	592	Shared Neighborhood Hits	47
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

SYNJ1_MOUSE
NC score	0.028767 (rank : 108)	θ value	0.813845 (rank : 94)
Query Neighborhood Hits	175	Target Neighborhood Hits	516	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

ACINU_MOUSE
NC score	0.028681 (rank : 109)	θ value	0.365318 (rank : 73)
Query Neighborhood Hits	175	Target Neighborhood Hits	712	Shared Neighborhood Hits	28
SwissProt Accessions	Q9JIX8, Q9CSN7, Q9CSR9, Q9CSX7, Q9R046, Q9R047	Gene names	Acin1, Acinus
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

EP400_HUMAN
NC score	0.026562 (rank : 110)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	175	Target Neighborhood Hits	556	Shared Neighborhood Hits	33
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

FRAT1_HUMAN
NC score	0.025970 (rank : 111)	θ value	0.47712 (rank : 81)
Query Neighborhood Hits	175	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q92837, Q8NE74, Q8TDW9	Gene names	FRAT1
Domain Architecture
Description	Proto-oncogene FRAT1 (Frequently rearranged in advanced T-cell lymphomas) (Frat-1).

T22D2_HUMAN
NC score	0.025744 (rank : 112)	θ value	5.27518 (rank : 145)
Query Neighborhood Hits	175	Target Neighborhood Hits	250	Shared Neighborhood Hits	20
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

RERE_HUMAN
NC score	0.025706 (rank : 113)	θ value	2.36792 (rank : 111)
Query Neighborhood Hits	175	Target Neighborhood Hits	779	Shared Neighborhood Hits	39
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

MORC2_HUMAN
NC score	0.025263 (rank : 114)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	175	Target Neighborhood Hits	207	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y6X9, Q9UF28, Q9Y6V2	Gene names	MORC2, KIAA0852, ZCWCC1
Domain Architecture
Description	MORC family CW-type zinc finger protein 2 (Zinc finger CW-type coiled- coil domain protein 1).

LMBL3_MOUSE
NC score	0.025206 (rank : 115)	θ value	0.62314 (rank : 84)
Query Neighborhood Hits	175	Target Neighborhood Hits	212	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BLB7, Q641L7, Q6ZPI2, Q8C0G4	Gene names	L3mbtl3
Domain Architecture	No domain graphic available
Description	Lethal(3)malignant brain tumor-like 3 protein (L(3)mbt-like 3 protein).

TF65_HUMAN
NC score	0.024390 (rank : 116)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	175	Target Neighborhood Hits	115	Shared Neighborhood Hits	19
SwissProt Accessions	Q04206, Q6SLK1	Gene names	RELA, NFKB3
Domain Architecture
Description	Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit).

ATBF1_MOUSE
NC score	0.024381 (rank : 117)	θ value	0.0736092 (rank : 50)
Query Neighborhood Hits	175	Target Neighborhood Hits	1841	Shared Neighborhood Hits	50
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

SMCA4_HUMAN
NC score	0.023487 (rank : 118)	θ value	1.06291 (rank : 101)
Query Neighborhood Hits	175	Target Neighborhood Hits	597	Shared Neighborhood Hits	28
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

PTN23_HUMAN
NC score	0.021528 (rank : 119)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	175	Target Neighborhood Hits	646	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

MOR2B_MOUSE
NC score	0.021387 (rank : 120)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	175	Target Neighborhood Hits	91	Shared Neighborhood Hits	6
SwissProt Accessions	Q8C5W4, Q8CG24	Gene names	Morc2b, Tce6
Domain Architecture	No domain graphic available
Description	MORC family CW-type zinc finger protein 2B (TCE6).

ATBF1_HUMAN
NC score	0.021285 (rank : 121)	θ value	1.06291 (rank : 96)
Query Neighborhood Hits	175	Target Neighborhood Hits	1547	Shared Neighborhood Hits	37
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

WNK2_HUMAN
NC score	0.020784 (rank : 122)	θ value	0.00665767 (rank : 36)
Query Neighborhood Hits	175	Target Neighborhood Hits	1407	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

MUC2_HUMAN
NC score	0.020508 (rank : 123)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	175	Target Neighborhood Hits	906	Shared Neighborhood Hits	35
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

WBS14_MOUSE
NC score	0.020410 (rank : 124)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	175	Target Neighborhood Hits	171	Shared Neighborhood Hits	17
SwissProt Accessions	Q99MZ3, Q99MY9, Q99MZ0, Q99MZ1, Q99MZ2, Q9JLM5	Gene names	Mlxipl, Mio, Wbscr14
Domain Architecture
Description	Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx interactor) (MLX-interacting protein-like).

FGD1_HUMAN
NC score	0.020331 (rank : 125)	θ value	0.0961366 (rank : 55)
Query Neighborhood Hits	175	Target Neighborhood Hits	367	Shared Neighborhood Hits	16
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

WBP11_MOUSE
NC score	0.020055 (rank : 126)	θ value	6.88961 (rank : 166)
Query Neighborhood Hits	175	Target Neighborhood Hits	362	Shared Neighborhood Hits	20
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

LDB3_HUMAN
NC score	0.018998 (rank : 127)	θ value	0.0961366 (rank : 57)
Query Neighborhood Hits	175	Target Neighborhood Hits	497	Shared Neighborhood Hits	18
SwissProt Accessions	O75112, Q5K6N9, Q5K6P0, Q5K6P1, Q96FH2, Q9Y4Z3, Q9Y4Z4, Q9Y4Z5	Gene names	LDB3, KIAA0613, ZASP
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher).

STA13_MOUSE
NC score	0.018647 (rank : 128)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	175	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

STA13_HUMAN
NC score	0.018421 (rank : 129)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	175	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

ENAH_HUMAN
NC score	0.017960 (rank : 130)	θ value	0.813845 (rank : 89)
Query Neighborhood Hits	175	Target Neighborhood Hits	784	Shared Neighborhood Hits	28
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

K0460_MOUSE
NC score	0.017800 (rank : 131)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	175	Target Neighborhood Hits	374	Shared Neighborhood Hits	24
SwissProt Accessions	Q6NXI6, Q3U3L8, Q6ZQA7	Gene names	Kiaa0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

LDB3_MOUSE
NC score	0.017745 (rank : 132)	θ value	1.06291 (rank : 97)
Query Neighborhood Hits	175	Target Neighborhood Hits	510	Shared Neighborhood Hits	25
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

G3BP_HUMAN
NC score	0.017312 (rank : 133)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	175	Target Neighborhood Hits	219	Shared Neighborhood Hits	8
SwissProt Accessions	Q13283	Gene names	G3BP, G3BP1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

PO2F2_HUMAN
NC score	0.016848 (rank : 134)	θ value	1.06291 (rank : 99)
Query Neighborhood Hits	175	Target Neighborhood Hits	379	Shared Neighborhood Hits	15
SwissProt Accessions	P09086, Q16648, Q9BRS4	Gene names	POU2F2, OCT2, OTF2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

TITIN_HUMAN
NC score	0.016816 (rank : 135)	θ value	0.00228821 (rank : 29)
Query Neighborhood Hits	175	Target Neighborhood Hits	2923	Shared Neighborhood Hits	66
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

FGD1_MOUSE
NC score	0.016619 (rank : 136)	θ value	3.0926 (rank : 116)
Query Neighborhood Hits	175	Target Neighborhood Hits	387	Shared Neighborhood Hits	21
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

RFX1_MOUSE
NC score	0.016583 (rank : 137)	θ value	1.81305 (rank : 107)
Query Neighborhood Hits	175	Target Neighborhood Hits	181	Shared Neighborhood Hits	13
SwissProt Accessions	P48377	Gene names	Rfx1
Domain Architecture
Description	DNA-binding protein RFX1.

DHX37_HUMAN
NC score	0.016495 (rank : 138)	θ value	0.365318 (rank : 75)
Query Neighborhood Hits	175	Target Neighborhood Hits	133	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

YTHD3_MOUSE
NC score	0.016402 (rank : 139)	θ value	5.27518 (rank : 147)
Query Neighborhood Hits	175	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BYK6, Q3UVI5, Q6NXJ6, Q6NXJ8, Q8BKB6	Gene names	Ythdf3
Domain Architecture	No domain graphic available
Description	YTH domain family protein 3.

VPS28_HUMAN
NC score	0.016200 (rank : 140)	θ value	6.88961 (rank : 164)
Query Neighborhood Hits	175	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UK41	Gene names	VPS28
Domain Architecture
Description	Vacuolar protein sorting-associated protein 28 homolog.

VPS28_MOUSE
NC score	0.016115 (rank : 141)	θ value	6.88961 (rank : 165)
Query Neighborhood Hits	175	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D1C8	Gene names	Vps28
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 28 homolog (Caspase- activated DNase inhibitor that interacts with ASK1) (CIIA).

PO6F2_MOUSE
NC score	0.015955 (rank : 142)	θ value	2.36792 (rank : 110)
Query Neighborhood Hits	175	Target Neighborhood Hits	639	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

SIN3A_HUMAN
NC score	0.015850 (rank : 143)	θ value	1.81305 (rank : 108)
Query Neighborhood Hits	175	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	Q96ST3, Q8N8N4, Q8NC83, Q8WV18, Q96L98, Q9UFQ1	Gene names	SIN3A
Domain Architecture
Description	Paired amphipathic helix protein Sin3a (Transcriptional corepressor Sin3a) (Histone deacetylase complex subunit Sin3a).

PO2F2_MOUSE
NC score	0.015136 (rank : 144)	θ value	0.813845 (rank : 92)
Query Neighborhood Hits	175	Target Neighborhood Hits	353	Shared Neighborhood Hits	9
SwissProt Accessions	Q00196, Q00197, Q00198, Q00199, Q00200, Q00201, Q05882, Q61995, Q61996, Q64245	Gene names	Pou2f2, Oct2, Otf2
Domain Architecture
Description	POU domain, class 2, transcription factor 2 (Octamer-binding transcription factor 2) (Oct-2) (OTF-2) (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2).

PO6F2_HUMAN
NC score	0.014751 (rank : 145)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	175	Target Neighborhood Hits	618	Shared Neighborhood Hits	22
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

UTP20_HUMAN
NC score	0.014066 (rank : 146)	θ value	2.36792 (rank : 113)
Query Neighborhood Hits	175	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

YTHD3_HUMAN
NC score	0.014060 (rank : 147)	θ value	4.03905 (rank : 129)
Query Neighborhood Hits	175	Target Neighborhood Hits	63	Shared Neighborhood Hits	7
SwissProt Accessions	Q7Z739, Q63Z37, Q659A3	Gene names	YTHDF3
Domain Architecture	No domain graphic available
Description	YTH domain family protein 3.

NCKX1_HUMAN
NC score	0.013339 (rank : 148)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	175	Target Neighborhood Hits	223	Shared Neighborhood Hits	7
SwissProt Accessions	O60721, O43485, O75184	Gene names	SLC24A1, KIAA0702, NCKX1
Domain Architecture
Description	Sodium/potassium/calcium exchanger 1 (Na(+)/K(+)/Ca(2+)-exchange protein 1) (Retinal rod Na-Ca+K exchanger).

ETV5_HUMAN
NC score	0.011854 (rank : 149)	θ value	4.03905 (rank : 122)
Query Neighborhood Hits	175	Target Neighborhood Hits	181	Shared Neighborhood Hits	24
SwissProt Accessions	P41161	Gene names	ETV5, ERM
Domain Architecture
Description	ETS translocation variant 5 (Ets-related protein ERM).

IRX3_HUMAN
NC score	0.011692 (rank : 150)	θ value	4.03905 (rank : 123)
Query Neighborhood Hits	175	Target Neighborhood Hits	342	Shared Neighborhood Hits	13
SwissProt Accessions	P78415, Q7Z4A4, Q7Z4A5, Q8IVC6	Gene names	IRX3, IRXB1
Domain Architecture
Description	Iroquois-class homeodomain protein IRX-3 (Iroquois homeobox protein 3) (Homeodomain protein IRXB1).

ABL2_HUMAN
NC score	0.011642 (rank : 151)	θ value	0.0330416 (rank : 43)
Query Neighborhood Hits	175	Target Neighborhood Hits	1045	Shared Neighborhood Hits	31
SwissProt Accessions	P42684, Q5T0X6, Q6NZY6	Gene names	ABL2, ABLL, ARG
Domain Architecture
Description	Tyrosine-protein kinase ABL2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Tyrosine kinase ARG).

ROBO4_HUMAN
NC score	0.011498 (rank : 152)	θ value	1.06291 (rank : 100)
Query Neighborhood Hits	175	Target Neighborhood Hits	364	Shared Neighborhood Hits	10
SwissProt Accessions	Q8WZ75, Q8TEG1, Q96JV6, Q9H718, Q9NWJ8	Gene names	ROBO4
Domain Architecture
Description	Roundabout homolog 4 precursor (Magic roundabout).

PRS6B_HUMAN
NC score	0.011097 (rank : 153)	θ value	0.163984 (rank : 62)
Query Neighborhood Hits	175	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	P43686, Q96FV5, Q9UBM3, Q9UEX3	Gene names	PSMC4, TBP7
Domain Architecture
Description	26S protease regulatory subunit 6B (Proteasome 26S subunit ATPase 4) (MIP224) (MB67-interacting protein) (TAT-binding protein 7) (TBP-7).

CRF_HUMAN
NC score	0.010984 (rank : 154)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	175	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	P06850	Gene names	CRH
Domain Architecture
Description	Corticoliberin precursor (Corticotropin-releasing factor) (CRF) (Corticotropin-releasing hormone).

KIF17_MOUSE
NC score	0.010913 (rank : 155)	θ value	0.0961366 (rank : 56)
Query Neighborhood Hits	175	Target Neighborhood Hits	452	Shared Neighborhood Hits	11
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

DDEF1_MOUSE
NC score	0.010214 (rank : 156)	θ value	3.0926 (rank : 114)
Query Neighborhood Hits	175	Target Neighborhood Hits	592	Shared Neighborhood Hits	25
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

AAK1_HUMAN
NC score	0.010021 (rank : 157)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	175	Target Neighborhood Hits	1077	Shared Neighborhood Hits	56
SwissProt Accessions	Q2M2I8, Q4ZFZ3, Q53RX6, Q9UPV4	Gene names	AAK1, KIAA1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

MKL2_MOUSE
NC score	0.010008 (rank : 158)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	175	Target Neighborhood Hits	269	Shared Neighborhood Hits	16
SwissProt Accessions	P59759	Gene names	Mkl2, Mrtfb
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B).

ABL1_MOUSE
NC score	0.009795 (rank : 159)	θ value	0.279714 (rank : 65)
Query Neighborhood Hits	175	Target Neighborhood Hits	1178	Shared Neighborhood Hits	36
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

SHAN1_HUMAN
NC score	0.009744 (rank : 160)	θ value	3.0926 (rank : 120)
Query Neighborhood Hits	175	Target Neighborhood Hits	1041	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

ABL1_HUMAN
NC score	0.009698 (rank : 161)	θ value	0.21417 (rank : 63)
Query Neighborhood Hits	175	Target Neighborhood Hits	1220	Shared Neighborhood Hits	36
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

WNK4_HUMAN
NC score	0.009695 (rank : 162)	θ value	1.06291 (rank : 102)
Query Neighborhood Hits	175	Target Neighborhood Hits	1043	Shared Neighborhood Hits	28
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

TMLH_HUMAN
NC score	0.008857 (rank : 163)	θ value	6.88961 (rank : 162)
Query Neighborhood Hits	175	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NVH6	Gene names	TMLHE, TMLH
Domain Architecture
Description	Trimethyllysine dioxygenase, mitochondrial precursor (EC 1.14.11.8) (Epsilon-trimethyllysine 2-oxoglutarate dioxygenase) (TML-alpha- ketoglutarate dioxygenase) (TML hydroxylase) (TML dioxygenase) (TMLD).

WNK4_MOUSE
NC score	0.008482 (rank : 164)	θ value	6.88961 (rank : 167)
Query Neighborhood Hits	175	Target Neighborhood Hits	961	Shared Neighborhood Hits	25
SwissProt Accessions	Q80UE6, Q4VAC1, Q80XB5, Q80XN2, Q8R0N0, Q8R340	Gene names	Wnk4, Prkwnk4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

TNC6B_HUMAN
NC score	0.008210 (rank : 165)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	175	Target Neighborhood Hits	256	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UPQ9, Q5TH52, Q8TBX2	Gene names	TNRC6B, KIAA1093
Domain Architecture
Description	Trinucleotide repeat-containing 6B protein.

STX4_HUMAN
NC score	0.007992 (rank : 166)	θ value	1.81305 (rank : 109)
Query Neighborhood Hits	175	Target Neighborhood Hits	266	Shared Neighborhood Hits	5
SwissProt Accessions	Q12846, Q15525	Gene names	STX4, STX4A
Domain Architecture
Description	Syntaxin-4 (NY-REN-31 antigen).

P66B_MOUSE
NC score	0.007659 (rank : 167)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	175	Target Neighborhood Hits	64	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VHR5, Q8C9Q3	Gene names	Gatad2b
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 beta (p66/p68) (GATA zinc finger domain- containing protein 2B).

GPR64_HUMAN
NC score	0.007608 (rank : 168)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	175	Target Neighborhood Hits	207	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

TREF1_MOUSE
NC score	0.007230 (rank : 169)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	175	Target Neighborhood Hits	682	Shared Neighborhood Hits	23
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

G3PT_HUMAN
NC score	0.006740 (rank : 170)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	175	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	O14556, O60823, Q6JTT9, Q9HCU6	Gene names	GAPDHS, GAPD2, GAPDH2, GAPDS
Domain Architecture
Description	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific (EC 1.2.1.12) (Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2) (GAPDH-2).

FGR_MOUSE
NC score	0.006493 (rank : 171)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	175	Target Neighborhood Hits	1069	Shared Neighborhood Hits	28
SwissProt Accessions	P14234, Q61404	Gene names	Fgr
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FGR_HUMAN
NC score	0.006406 (rank : 172)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	175	Target Neighborhood Hits	1067	Shared Neighborhood Hits	29
SwissProt Accessions	P09769, Q9UIQ3	Gene names	FGR, SRC2
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase FGR (EC 2.7.10.2) (P55-FGR) (C- FGR).

FYN_MOUSE
NC score	0.006293 (rank : 173)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	175	Target Neighborhood Hits	1073	Shared Neighborhood Hits	30
SwissProt Accessions	P39688	Gene names	Fyn
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn).

LTBP4_MOUSE
NC score	0.006255 (rank : 174)	θ value	0.279714 (rank : 70)
Query Neighborhood Hits	175	Target Neighborhood Hits	607	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

TBC10_HUMAN
NC score	0.006207 (rank : 175)	θ value	6.88961 (rank : 161)
Query Neighborhood Hits	175	Target Neighborhood Hits	64	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BXI6, O76053, Q543A2	Gene names	TBC1D10A, EPI64, TBC1D10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

FYN_HUMAN
NC score	0.005869 (rank : 176)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	175	Target Neighborhood Hits	1078	Shared Neighborhood Hits	28
SwissProt Accessions	P06241	Gene names	FYN
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase Fyn (EC 2.7.10.2) (p59-Fyn) (Protooncogene Syn) (SLK).

CCNB1_MOUSE
NC score	0.005842 (rank : 177)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	175	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	P24860	Gene names	Ccnb1, Ccn-2, Ccnb1-rs13, Cycb, Cycb1
Domain Architecture
Description	G2/mitotic-specific cyclin-B1.

TSH3_MOUSE
NC score	0.005752 (rank : 178)	θ value	5.27518 (rank : 146)
Query Neighborhood Hits	175	Target Neighborhood Hits	590	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CGV9, Q5DTX4	Gene names	Tshz3, Kiaa1474, Tsh3, Zfp537, Znf537
Domain Architecture	No domain graphic available
Description	Teashirt homolog 3 (Zinc finger protein 537).

MYH8_HUMAN
NC score	0.005653 (rank : 179)	θ value	4.03905 (rank : 124)
Query Neighborhood Hits	175	Target Neighborhood Hits	1610	Shared Neighborhood Hits	37
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

KSR2_HUMAN
NC score	0.005482 (rank : 180)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	175	Target Neighborhood Hits	920	Shared Neighborhood Hits	21
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

SSH1_HUMAN
NC score	0.005155 (rank : 181)	θ value	6.88961 (rank : 160)
Query Neighborhood Hits	175	Target Neighborhood Hits	164	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

SPEG_HUMAN
NC score	0.004756 (rank : 182)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	175	Target Neighborhood Hits	1762	Shared Neighborhood Hits	52
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

MYH8_MOUSE
NC score	0.004099 (rank : 183)	θ value	4.03905 (rank : 125)
Query Neighborhood Hits	175	Target Neighborhood Hits	1600	Shared Neighborhood Hits	31
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

M3K14_HUMAN
NC score	0.003573 (rank : 184)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	175	Target Neighborhood Hits	887	Shared Neighborhood Hits	25
SwissProt Accessions	Q99558, Q8IYN1	Gene names	MAP3K14, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK) (HsNIK).

NRK_HUMAN
NC score	0.003573 (rank : 185)	θ value	3.0926 (rank : 118)
Query Neighborhood Hits	175	Target Neighborhood Hits	931	Shared Neighborhood Hits	19
SwissProt Accessions	Q7Z2Y5, Q32ND6, Q5H9K2, Q6ZMP2	Gene names	NRK
Domain Architecture	No domain graphic available
Description	Nik-related protein kinase (EC 2.7.11.1).

LAP4_HUMAN
NC score	0.003250 (rank : 186)	θ value	3.0926 (rank : 117)
Query Neighborhood Hits	175	Target Neighborhood Hits	608	Shared Neighborhood Hits	12
SwissProt Accessions	Q14160, Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1	Gene names	SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL
Domain Architecture	No domain graphic available
Description	Protein LAP4 (Protein scribble homolog) (hScrib).

MRCKA_HUMAN
NC score	0.002678 (rank : 187)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	175	Target Neighborhood Hits	1999	Shared Neighborhood Hits	49
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

MTF1_HUMAN
NC score	0.000379 (rank : 188)	θ value	0.47712 (rank : 82)
Query Neighborhood Hits	175	Target Neighborhood Hits	814	Shared Neighborhood Hits	17
SwissProt Accessions	Q14872, Q96CB1	Gene names	MTF1
Domain Architecture	No domain graphic available
Description	Metal-regulatory transcription factor 1 (Transcription factor MTF-1) (MRE-binding transcription factor).

ZXDA_HUMAN
NC score	-0.001132 (rank : 189)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	175	Target Neighborhood Hits	750	Shared Neighborhood Hits	12
SwissProt Accessions	P98168, Q9UJP7	Gene names	ZXDA
Domain Architecture	No domain graphic available
Description	Zinc finger X-linked protein ZXDA.

KLF11_HUMAN
NC score	-0.001221 (rank : 190)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	175	Target Neighborhood Hits	717	Shared Neighborhood Hits	10
SwissProt Accessions	O14901	Gene names	KLF11, FKLF, TIEG2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2).

KLF11_MOUSE
NC score	-0.001430 (rank : 191)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	175	Target Neighborhood Hits	714	Shared Neighborhood Hits	9
SwissProt Accessions	Q9EPF4	Gene names	Klf11, Tieg2
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 11 (Transforming growth factor-beta-inducible early growth response protein 2) (TGFB-inducible early growth response protein 2) (TIEG-2).