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Network neighborhood for query Sequence : CCNB1_MOUSE

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CCNB1_MOUSE
SwissProt Accessions	P24860	Gene names	Ccnb1, Ccn-2, Ccnb1-rs13, Cycb, Cycb1
Domain Architecture
Description	G2/mitotic-specific cyclin-B1.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CCNB1_HUMAN
θ value	0 (rank : 1)	NC score	0.995640 (rank : 2)
Query Neighborhood Hits	48	Target Neighborhood Hits	61	Shared Neighborhood Hits	36
SwissProt Accessions	P14635	Gene names	CCNB1, CCNB
Domain Architecture
Description	G2/mitotic-specific cyclin-B1.

CCNB1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	48	Target Neighborhood Hits	48	Shared Neighborhood Hits	48
SwissProt Accessions	P24860	Gene names	Ccnb1, Ccn-2, Ccnb1-rs13, Cycb, Cycb1
Domain Architecture
Description	G2/mitotic-specific cyclin-B1.

CCNB2_HUMAN
θ value	2.71407e-105 (rank : 3)	NC score	0.983037 (rank : 3)
Query Neighborhood Hits	48	Target Neighborhood Hits	35	Shared Neighborhood Hits	29
SwissProt Accessions	O95067	Gene names	CCNB2
Domain Architecture
Description	G2/mitotic-specific cyclin-B2.

CCNB2_MOUSE
θ value	2.15048e-102 (rank : 4)	NC score	0.982154 (rank : 4)
Query Neighborhood Hits	48	Target Neighborhood Hits	42	Shared Neighborhood Hits	29
SwissProt Accessions	P30276	Gene names	Ccnb2, Cycb2
Domain Architecture
Description	G2/mitotic-specific cyclin-B2.

CCNA1_HUMAN
θ value	2.67181e-44 (rank : 5)	NC score	0.917645 (rank : 5)
Query Neighborhood Hits	48	Target Neighborhood Hits	37	Shared Neighborhood Hits	33
SwissProt Accessions	P78396	Gene names	CCNA1
Domain Architecture
Description	Cyclin-A1.

CCNA1_MOUSE
θ value	3.48949e-44 (rank : 6)	NC score	0.917405 (rank : 6)
Query Neighborhood Hits	48	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	Q61456	Gene names	Ccna1
Domain Architecture
Description	Cyclin-A1.

CCNA2_MOUSE
θ value	1.05066e-40 (rank : 7)	NC score	0.907365 (rank : 7)
Query Neighborhood Hits	48	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	P51943, Q61459	Gene names	Ccna2, Ccna, Cyca
Domain Architecture
Description	Cyclin-A2 (Cyclin-A).

CCNB3_MOUSE
θ value	1.05066e-40 (rank : 8)	NC score	0.840566 (rank : 9)
Query Neighborhood Hits	48	Target Neighborhood Hits	211	Shared Neighborhood Hits	27
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

CCNB3_HUMAN
θ value	1.3722e-40 (rank : 9)	NC score	0.747427 (rank : 14)
Query Neighborhood Hits	48	Target Neighborhood Hits	368	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

CCNA2_HUMAN
θ value	1.51715e-39 (rank : 10)	NC score	0.905285 (rank : 8)
Query Neighborhood Hits	48	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	P20248	Gene names	CCNA2, CCN1, CCNA
Domain Architecture
Description	Cyclin-A2 (Cyclin-A).

CCNE2_MOUSE
θ value	1.2077e-20 (rank : 11)	NC score	0.792233 (rank : 10)
Query Neighborhood Hits	48	Target Neighborhood Hits	30	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z238, Q9QWU5	Gene names	Ccne2
Domain Architecture
Description	G1/S-specific cyclin-E2.

CCNE2_HUMAN
θ value	5.07402e-19 (rank : 12)	NC score	0.786608 (rank : 12)
Query Neighborhood Hits	48	Target Neighborhood Hits	31	Shared Neighborhood Hits	28
SwissProt Accessions	O96020, O95439	Gene names	CCNE2
Domain Architecture
Description	G1/S-specific cyclin-E2.

CCNE1_HUMAN
θ value	6.62687e-19 (rank : 13)	NC score	0.787218 (rank : 11)
Query Neighborhood Hits	48	Target Neighborhood Hits	34	Shared Neighborhood Hits	28
SwissProt Accessions	P24864, Q14091, Q8NFG1, Q92501	Gene names	CCNE1, CCNE
Domain Architecture
Description	G1/S-specific cyclin-E1.

CCNE1_MOUSE
θ value	7.32683e-18 (rank : 14)	NC score	0.778067 (rank : 13)
Query Neighborhood Hits	48	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	Q61457	Gene names	Ccne1, Ccne
Domain Architecture
Description	G1/S-specific cyclin-E1.

CCNF_HUMAN
θ value	2.7842e-17 (rank : 15)	NC score	0.705307 (rank : 18)
Query Neighborhood Hits	48	Target Neighborhood Hits	46	Shared Neighborhood Hits	23
SwissProt Accessions	P41002, Q96EG9	Gene names	CCNF
Domain Architecture
Description	G2/mitotic-specific cyclin-F.

CCND1_MOUSE
θ value	1.52774e-15 (rank : 16)	NC score	0.735961 (rank : 15)
Query Neighborhood Hits	48	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	P25322	Gene names	Ccnd1, Cyl-1
Domain Architecture
Description	G1/S-specific cyclin-D1.

CCNF_MOUSE
θ value	3.40345e-15 (rank : 17)	NC score	0.701730 (rank : 20)
Query Neighborhood Hits	48	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	P51944, Q60797, Q60799	Gene names	Ccnf
Domain Architecture
Description	G2/mitotic-specific cyclin-F.

CCND1_HUMAN
θ value	2.88119e-14 (rank : 18)	NC score	0.727666 (rank : 16)
Query Neighborhood Hits	48	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	P24385, Q6LEF0	Gene names	CCND1, BCL1, PRAD1
Domain Architecture
Description	G1/S-specific cyclin-D1 (PRAD1 oncogene) (BCL-1 oncogene).

CCND3_HUMAN
θ value	7.09661e-13 (rank : 19)	NC score	0.713870 (rank : 17)
Query Neighborhood Hits	48	Target Neighborhood Hits	33	Shared Neighborhood Hits	29
SwissProt Accessions	P30281, Q5T8J0, Q96F49	Gene names	CCND3
Domain Architecture
Description	G1/S-specific cyclin-D3.

CCND3_MOUSE
θ value	1.02475e-11 (rank : 20)	NC score	0.702503 (rank : 19)
Query Neighborhood Hits	48	Target Neighborhood Hits	29	Shared Neighborhood Hits	27
SwissProt Accessions	P30282, Q62391, Q99KP2	Gene names	Ccnd3, Cyl-3
Domain Architecture
Description	G1/S-specific cyclin-D3.

CCND2_MOUSE
θ value	6.64225e-11 (rank : 21)	NC score	0.684794 (rank : 22)
Query Neighborhood Hits	48	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	P30280	Gene names	Ccnd2, Cyl-2
Domain Architecture
Description	G1/S-specific cyclin-D2.

CCND2_HUMAN
θ value	8.67504e-11 (rank : 22)	NC score	0.692094 (rank : 21)
Query Neighborhood Hits	48	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	P30279, Q13955	Gene names	CCND2
Domain Architecture
Description	G1/S-specific cyclin-D2.

CCNI_MOUSE
θ value	8.40245e-06 (rank : 23)	NC score	0.484141 (rank : 24)
Query Neighborhood Hits	48	Target Neighborhood Hits	35	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z2V9	Gene names	Ccni
Domain Architecture
Description	Cyclin-I.

CCNI_HUMAN
θ value	1.43324e-05 (rank : 24)	NC score	0.506582 (rank : 23)
Query Neighborhood Hits	48	Target Neighborhood Hits	39	Shared Neighborhood Hits	27
SwissProt Accessions	Q14094	Gene names	CCNI
Domain Architecture
Description	Cyclin-I.

CCNG1_HUMAN
θ value	0.00175202 (rank : 25)	NC score	0.461532 (rank : 26)
Query Neighborhood Hits	48	Target Neighborhood Hits	31	Shared Neighborhood Hits	29
SwissProt Accessions	P51959, Q15757, Q96L32	Gene names	CCNG1, CCNG, CYCG1
Domain Architecture
Description	Cyclin-G1 (Cyclin-G).

CCNG1_MOUSE
θ value	0.00175202 (rank : 26)	NC score	0.474128 (rank : 25)
Query Neighborhood Hits	48	Target Neighborhood Hits	32	Shared Neighborhood Hits	29
SwissProt Accessions	P51945, O54779	Gene names	Ccng1, Ccng
Domain Architecture
Description	Cyclin-G1 (Cyclin-G).

CCNG2_HUMAN
θ value	0.0113563 (rank : 27)	NC score	0.430817 (rank : 28)
Query Neighborhood Hits	48	Target Neighborhood Hits	27	Shared Neighborhood Hits	25
SwissProt Accessions	Q16589	Gene names	CCNG2
Domain Architecture
Description	Cyclin-G2.

CCNG2_MOUSE
θ value	0.0148317 (rank : 28)	NC score	0.433186 (rank : 27)
Query Neighborhood Hits	48	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	O08918, O35612	Gene names	Ccng2
Domain Architecture
Description	Cyclin-G2.

UNG2_HUMAN
θ value	0.0252991 (rank : 29)	NC score	0.353582 (rank : 29)
Query Neighborhood Hits	48	Target Neighborhood Hits	22	Shared Neighborhood Hits	17
SwissProt Accessions	P22674	Gene names	UNG2
Domain Architecture
Description	Uracil-DNA glycosylase 2 (EC 3.2.2.-) (UDG 2).

NHRF2_HUMAN
θ value	0.0431538 (rank : 30)	NC score	0.022749 (rank : 37)
Query Neighborhood Hits	48	Target Neighborhood Hits	197	Shared Neighborhood Hits	2
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

IER2_HUMAN
θ value	1.06291 (rank : 31)	NC score	0.029588 (rank : 36)
Query Neighborhood Hits	48	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BTL4, Q03827, Q2TAZ2	Gene names	IER2, ETR101
Domain Architecture	No domain graphic available
Description	Immediate early response gene 2 protein (Protein ETR101).

CCNL1_HUMAN
θ value	1.38821 (rank : 32)	NC score	0.072138 (rank : 33)
Query Neighborhood Hits	48	Target Neighborhood Hits	79	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

CCNL1_MOUSE
θ value	1.38821 (rank : 33)	NC score	0.072003 (rank : 34)
Query Neighborhood Hits	48	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	Q52KE7, Q8BQ75, Q8R5H9, Q922K0, Q9CSZ3, Q9WV44	Gene names	Ccnl1, Ania6a, Ccn1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L) (Cyclin Ania-6a).

CCNL2_MOUSE
θ value	1.38821 (rank : 34)	NC score	0.078447 (rank : 32)
Query Neighborhood Hits	48	Target Neighborhood Hits	78	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJA7, Q5XK66, Q60995, Q8C136, Q8CIJ8, Q99L73, Q9QXH5	Gene names	Ccnl2, Ania6b
Domain Architecture	No domain graphic available
Description	Cyclin-L2 (Cyclin Ania-6b) (Paneth cell-enhanced expression protein) (PCEE).

DOCK1_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.010229 (rank : 41)
Query Neighborhood Hits	48	Target Neighborhood Hits	191	Shared Neighborhood Hits	4
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

CCNL2_HUMAN
θ value	2.36792 (rank : 36)	NC score	0.068863 (rank : 35)
Query Neighborhood Hits	48	Target Neighborhood Hits	100	Shared Neighborhood Hits	10
SwissProt Accessions	Q96S94, Q5T2N5, Q5T2N6, Q6IQ12, Q7Z4Z8, Q8N3C9, Q8N3D5, Q8NHE3, Q8TEL0, Q96B00	Gene names	CCNL2
Domain Architecture	No domain graphic available
Description	Cyclin-L2 (Paneth cell-enhanced expression protein).

M3K4_MOUSE
θ value	2.36792 (rank : 37)	NC score	-0.000144 (rank : 49)
Query Neighborhood Hits	48	Target Neighborhood Hits	924	Shared Neighborhood Hits	3
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

LMNB2_HUMAN
θ value	3.0926 (rank : 38)	NC score	0.004623 (rank : 45)
Query Neighborhood Hits	48	Target Neighborhood Hits	723	Shared Neighborhood Hits	5
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

TLR7_HUMAN
θ value	3.0926 (rank : 39)	NC score	0.003381 (rank : 46)
Query Neighborhood Hits	48	Target Neighborhood Hits	312	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYK1, Q9NR98	Gene names	TLR7
Domain Architecture
Description	Toll-like receptor 7 precursor.

BUB1B_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.012350 (rank : 40)
Query Neighborhood Hits	48	Target Neighborhood Hits	202	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z1S0	Gene names	Bub1b, Mad3l
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L).

SAFB2_MOUSE
θ value	5.27518 (rank : 41)	NC score	0.005299 (rank : 44)
Query Neighborhood Hits	48	Target Neighborhood Hits	581	Shared Neighborhood Hits	4
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

STAT2_MOUSE
θ value	5.27518 (rank : 42)	NC score	0.005842 (rank : 43)
Query Neighborhood Hits	48	Target Neighborhood Hits	175	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

GGPPS_MOUSE
θ value	6.88961 (rank : 43)	NC score	0.016657 (rank : 39)
Query Neighborhood Hits	48	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTN0	Gene names	Ggps1
Domain Architecture
Description	Geranylgeranyl pyrophosphate synthetase (GGPP synthetase) (GGPPSase) (Geranylgeranyl diphosphate synthase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)].

SELPL_MOUSE
θ value	6.88961 (rank : 44)	NC score	0.022171 (rank : 38)
Query Neighborhood Hits	48	Target Neighborhood Hits	588	Shared Neighborhood Hits	3
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

SRGP2_HUMAN
θ value	6.88961 (rank : 45)	NC score	0.003070 (rank : 47)
Query Neighborhood Hits	48	Target Neighborhood Hits	331	Shared Neighborhood Hits	3
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

BPAEA_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.000812 (rank : 48)
Query Neighborhood Hits	48	Target Neighborhood Hits	1369	Shared Neighborhood Hits	5
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

ZBTB5_MOUSE
θ value	8.99809 (rank : 47)	NC score	-0.002615 (rank : 50)
Query Neighborhood Hits	48	Target Neighborhood Hits	801	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TQG0, Q3TVR7, Q6GV09, Q8BIB5	Gene names	Zbtb5, Kiaa0354
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 5 (Transcription factor ZNF-POZ).

ZWINT_MOUSE
θ value	8.99809 (rank : 48)	NC score	0.006218 (rank : 42)
Query Neighborhood Hits	48	Target Neighborhood Hits	497	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

CCNK_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.103151 (rank : 30)
Query Neighborhood Hits	48	Target Neighborhood Hits	101	Shared Neighborhood Hits	16
SwissProt Accessions	O75909, Q96B63, Q9NNY9	Gene names	CCNK, CPR4
Domain Architecture
Description	Cyclin-K.

CCNK_MOUSE
θ value	θ > 10 (rank : 50)	NC score	0.084229 (rank : 31)
Query Neighborhood Hits	48	Target Neighborhood Hits	350	Shared Neighborhood Hits	16
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

Hits sorted by NC score

CCNB1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	48	Target Neighborhood Hits	48	Shared Neighborhood Hits	48
SwissProt Accessions	P24860	Gene names	Ccnb1, Ccn-2, Ccnb1-rs13, Cycb, Cycb1
Domain Architecture
Description	G2/mitotic-specific cyclin-B1.

CCNB1_HUMAN
NC score	0.995640 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	48	Target Neighborhood Hits	61	Shared Neighborhood Hits	36
SwissProt Accessions	P14635	Gene names	CCNB1, CCNB
Domain Architecture
Description	G2/mitotic-specific cyclin-B1.

CCNB2_HUMAN
NC score	0.983037 (rank : 3)	θ value	2.71407e-105 (rank : 3)
Query Neighborhood Hits	48	Target Neighborhood Hits	35	Shared Neighborhood Hits	29
SwissProt Accessions	O95067	Gene names	CCNB2
Domain Architecture
Description	G2/mitotic-specific cyclin-B2.

CCNB2_MOUSE
NC score	0.982154 (rank : 4)	θ value	2.15048e-102 (rank : 4)
Query Neighborhood Hits	48	Target Neighborhood Hits	42	Shared Neighborhood Hits	29
SwissProt Accessions	P30276	Gene names	Ccnb2, Cycb2
Domain Architecture
Description	G2/mitotic-specific cyclin-B2.

CCNA1_HUMAN
NC score	0.917645 (rank : 5)	θ value	2.67181e-44 (rank : 5)
Query Neighborhood Hits	48	Target Neighborhood Hits	37	Shared Neighborhood Hits	33
SwissProt Accessions	P78396	Gene names	CCNA1
Domain Architecture
Description	Cyclin-A1.

CCNA1_MOUSE
NC score	0.917405 (rank : 6)	θ value	3.48949e-44 (rank : 6)
Query Neighborhood Hits	48	Target Neighborhood Hits	41	Shared Neighborhood Hits	33
SwissProt Accessions	Q61456	Gene names	Ccna1
Domain Architecture
Description	Cyclin-A1.

CCNA2_MOUSE
NC score	0.907365 (rank : 7)	θ value	1.05066e-40 (rank : 7)
Query Neighborhood Hits	48	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	P51943, Q61459	Gene names	Ccna2, Ccna, Cyca
Domain Architecture
Description	Cyclin-A2 (Cyclin-A).

CCNA2_HUMAN
NC score	0.905285 (rank : 8)	θ value	1.51715e-39 (rank : 10)
Query Neighborhood Hits	48	Target Neighborhood Hits	46	Shared Neighborhood Hits	33
SwissProt Accessions	P20248	Gene names	CCNA2, CCN1, CCNA
Domain Architecture
Description	Cyclin-A2 (Cyclin-A).

CCNB3_MOUSE
NC score	0.840566 (rank : 9)	θ value	1.05066e-40 (rank : 8)
Query Neighborhood Hits	48	Target Neighborhood Hits	211	Shared Neighborhood Hits	27
SwissProt Accessions	Q810T2, Q810T3, Q8VDC8	Gene names	Ccnb3, Cycb3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

CCNE2_MOUSE
NC score	0.792233 (rank : 10)	θ value	1.2077e-20 (rank : 11)
Query Neighborhood Hits	48	Target Neighborhood Hits	30	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Z238, Q9QWU5	Gene names	Ccne2
Domain Architecture
Description	G1/S-specific cyclin-E2.

CCNE1_HUMAN
NC score	0.787218 (rank : 11)	θ value	6.62687e-19 (rank : 13)
Query Neighborhood Hits	48	Target Neighborhood Hits	34	Shared Neighborhood Hits	28
SwissProt Accessions	P24864, Q14091, Q8NFG1, Q92501	Gene names	CCNE1, CCNE
Domain Architecture
Description	G1/S-specific cyclin-E1.

CCNE2_HUMAN
NC score	0.786608 (rank : 12)	θ value	5.07402e-19 (rank : 12)
Query Neighborhood Hits	48	Target Neighborhood Hits	31	Shared Neighborhood Hits	28
SwissProt Accessions	O96020, O95439	Gene names	CCNE2
Domain Architecture
Description	G1/S-specific cyclin-E2.

CCNE1_MOUSE
NC score	0.778067 (rank : 13)	θ value	7.32683e-18 (rank : 14)
Query Neighborhood Hits	48	Target Neighborhood Hits	36	Shared Neighborhood Hits	28
SwissProt Accessions	Q61457	Gene names	Ccne1, Ccne
Domain Architecture
Description	G1/S-specific cyclin-E1.

CCNB3_HUMAN
NC score	0.747427 (rank : 14)	θ value	1.3722e-40 (rank : 9)
Query Neighborhood Hits	48	Target Neighborhood Hits	368	Shared Neighborhood Hits	29
SwissProt Accessions	Q8WWL7, Q96SB5, Q96SB6, Q96SB7, Q9NT38	Gene names	CCNB3, CYCB3
Domain Architecture
Description	G2/mitotic-specific cyclin-B3.

CCND1_MOUSE
NC score	0.735961 (rank : 15)	θ value	1.52774e-15 (rank : 16)
Query Neighborhood Hits	48	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	P25322	Gene names	Ccnd1, Cyl-1
Domain Architecture
Description	G1/S-specific cyclin-D1.

CCND1_HUMAN
NC score	0.727666 (rank : 16)	θ value	2.88119e-14 (rank : 18)
Query Neighborhood Hits	48	Target Neighborhood Hits	37	Shared Neighborhood Hits	28
SwissProt Accessions	P24385, Q6LEF0	Gene names	CCND1, BCL1, PRAD1
Domain Architecture
Description	G1/S-specific cyclin-D1 (PRAD1 oncogene) (BCL-1 oncogene).

CCND3_HUMAN
NC score	0.713870 (rank : 17)	θ value	7.09661e-13 (rank : 19)
Query Neighborhood Hits	48	Target Neighborhood Hits	33	Shared Neighborhood Hits	29
SwissProt Accessions	P30281, Q5T8J0, Q96F49	Gene names	CCND3
Domain Architecture
Description	G1/S-specific cyclin-D3.

CCNF_HUMAN
NC score	0.705307 (rank : 18)	θ value	2.7842e-17 (rank : 15)
Query Neighborhood Hits	48	Target Neighborhood Hits	46	Shared Neighborhood Hits	23
SwissProt Accessions	P41002, Q96EG9	Gene names	CCNF
Domain Architecture
Description	G2/mitotic-specific cyclin-F.

CCND3_MOUSE
NC score	0.702503 (rank : 19)	θ value	1.02475e-11 (rank : 20)
Query Neighborhood Hits	48	Target Neighborhood Hits	29	Shared Neighborhood Hits	27
SwissProt Accessions	P30282, Q62391, Q99KP2	Gene names	Ccnd3, Cyl-3
Domain Architecture
Description	G1/S-specific cyclin-D3.

CCNF_MOUSE
NC score	0.701730 (rank : 20)	θ value	3.40345e-15 (rank : 17)
Query Neighborhood Hits	48	Target Neighborhood Hits	45	Shared Neighborhood Hits	24
SwissProt Accessions	P51944, Q60797, Q60799	Gene names	Ccnf
Domain Architecture
Description	G2/mitotic-specific cyclin-F.

CCND2_HUMAN
NC score	0.692094 (rank : 21)	θ value	8.67504e-11 (rank : 22)
Query Neighborhood Hits	48	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	P30279, Q13955	Gene names	CCND2
Domain Architecture
Description	G1/S-specific cyclin-D2.

CCND2_MOUSE
NC score	0.684794 (rank : 22)	θ value	6.64225e-11 (rank : 21)
Query Neighborhood Hits	48	Target Neighborhood Hits	37	Shared Neighborhood Hits	29
SwissProt Accessions	P30280	Gene names	Ccnd2, Cyl-2
Domain Architecture
Description	G1/S-specific cyclin-D2.

CCNI_HUMAN
NC score	0.506582 (rank : 23)	θ value	1.43324e-05 (rank : 24)
Query Neighborhood Hits	48	Target Neighborhood Hits	39	Shared Neighborhood Hits	27
SwissProt Accessions	Q14094	Gene names	CCNI
Domain Architecture
Description	Cyclin-I.

CCNI_MOUSE
NC score	0.484141 (rank : 24)	θ value	8.40245e-06 (rank : 23)
Query Neighborhood Hits	48	Target Neighborhood Hits	35	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Z2V9	Gene names	Ccni
Domain Architecture
Description	Cyclin-I.

CCNG1_MOUSE
NC score	0.474128 (rank : 25)	θ value	0.00175202 (rank : 26)
Query Neighborhood Hits	48	Target Neighborhood Hits	32	Shared Neighborhood Hits	29
SwissProt Accessions	P51945, O54779	Gene names	Ccng1, Ccng
Domain Architecture
Description	Cyclin-G1 (Cyclin-G).

CCNG1_HUMAN
NC score	0.461532 (rank : 26)	θ value	0.00175202 (rank : 25)
Query Neighborhood Hits	48	Target Neighborhood Hits	31	Shared Neighborhood Hits	29
SwissProt Accessions	P51959, Q15757, Q96L32	Gene names	CCNG1, CCNG, CYCG1
Domain Architecture
Description	Cyclin-G1 (Cyclin-G).

CCNG2_MOUSE
NC score	0.433186 (rank : 27)	θ value	0.0148317 (rank : 28)
Query Neighborhood Hits	48	Target Neighborhood Hits	29	Shared Neighborhood Hits	26
SwissProt Accessions	O08918, O35612	Gene names	Ccng2
Domain Architecture
Description	Cyclin-G2.

CCNG2_HUMAN
NC score	0.430817 (rank : 28)	θ value	0.0113563 (rank : 27)
Query Neighborhood Hits	48	Target Neighborhood Hits	27	Shared Neighborhood Hits	25
SwissProt Accessions	Q16589	Gene names	CCNG2
Domain Architecture
Description	Cyclin-G2.

UNG2_HUMAN
NC score	0.353582 (rank : 29)	θ value	0.0252991 (rank : 29)
Query Neighborhood Hits	48	Target Neighborhood Hits	22	Shared Neighborhood Hits	17
SwissProt Accessions	P22674	Gene names	UNG2
Domain Architecture
Description	Uracil-DNA glycosylase 2 (EC 3.2.2.-) (UDG 2).

CCNK_HUMAN
NC score	0.103151 (rank : 30)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	48	Target Neighborhood Hits	101	Shared Neighborhood Hits	16
SwissProt Accessions	O75909, Q96B63, Q9NNY9	Gene names	CCNK, CPR4
Domain Architecture
Description	Cyclin-K.

CCNK_MOUSE
NC score	0.084229 (rank : 31)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	48	Target Neighborhood Hits	350	Shared Neighborhood Hits	16
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CCNL2_MOUSE
NC score	0.078447 (rank : 32)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	48	Target Neighborhood Hits	78	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JJA7, Q5XK66, Q60995, Q8C136, Q8CIJ8, Q99L73, Q9QXH5	Gene names	Ccnl2, Ania6b
Domain Architecture	No domain graphic available
Description	Cyclin-L2 (Cyclin Ania-6b) (Paneth cell-enhanced expression protein) (PCEE).

CCNL1_HUMAN
NC score	0.072138 (rank : 33)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	48	Target Neighborhood Hits	79	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UK58, Q6NVY9, Q6UWS7, Q8NI48, Q96QT0, Q9NZF3	Gene names	CCNL1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L).

CCNL1_MOUSE
NC score	0.072003 (rank : 34)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	48	Target Neighborhood Hits	71	Shared Neighborhood Hits	10
SwissProt Accessions	Q52KE7, Q8BQ75, Q8R5H9, Q922K0, Q9CSZ3, Q9WV44	Gene names	Ccnl1, Ania6a, Ccn1
Domain Architecture	No domain graphic available
Description	Cyclin-L1 (Cyclin-L) (Cyclin Ania-6a).

CCNL2_HUMAN
NC score	0.068863 (rank : 35)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	48	Target Neighborhood Hits	100	Shared Neighborhood Hits	10
SwissProt Accessions	Q96S94, Q5T2N5, Q5T2N6, Q6IQ12, Q7Z4Z8, Q8N3C9, Q8N3D5, Q8NHE3, Q8TEL0, Q96B00	Gene names	CCNL2
Domain Architecture	No domain graphic available
Description	Cyclin-L2 (Paneth cell-enhanced expression protein).

IER2_HUMAN
NC score	0.029588 (rank : 36)	θ value	1.06291 (rank : 31)
Query Neighborhood Hits	48	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BTL4, Q03827, Q2TAZ2	Gene names	IER2, ETR101
Domain Architecture	No domain graphic available
Description	Immediate early response gene 2 protein (Protein ETR101).

NHRF2_HUMAN
NC score	0.022749 (rank : 37)	θ value	0.0431538 (rank : 30)
Query Neighborhood Hits	48	Target Neighborhood Hits	197	Shared Neighborhood Hits	2
SwissProt Accessions	Q15599, O00272, O00556	Gene names	SLC9A3R2, NHERF2
Domain Architecture
Description	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP- 1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen exchanger regulatory factor 2).

SELPL_MOUSE
NC score	0.022171 (rank : 38)	θ value	6.88961 (rank : 44)
Query Neighborhood Hits	48	Target Neighborhood Hits	588	Shared Neighborhood Hits	3
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

GGPPS_MOUSE
NC score	0.016657 (rank : 39)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	48	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WTN0	Gene names	Ggps1
Domain Architecture
Description	Geranylgeranyl pyrophosphate synthetase (GGPP synthetase) (GGPPSase) (Geranylgeranyl diphosphate synthase) [Includes: Dimethylallyltranstransferase (EC 2.5.1.1); Geranyltranstransferase (EC 2.5.1.10); Farnesyltranstransferase (EC 2.5.1.29)].

BUB1B_MOUSE
NC score	0.012350 (rank : 40)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	48	Target Neighborhood Hits	202	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z1S0	Gene names	Bub1b, Mad3l
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L).

DOCK1_HUMAN
NC score	0.010229 (rank : 41)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	48	Target Neighborhood Hits	191	Shared Neighborhood Hits	4
SwissProt Accessions	Q14185	Gene names	DOCK1
Domain Architecture
Description	Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180).

ZWINT_MOUSE
NC score	0.006218 (rank : 42)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	48	Target Neighborhood Hits	497	Shared Neighborhood Hits	5
SwissProt Accessions	Q9CQU5, Q3UYT8, Q91VI4, Q9D0W9	Gene names	Zwint, D10Ertd749e
Domain Architecture	No domain graphic available
Description	ZW10 interactor (ZW10-interacting protein 1) (Zwint-1).

STAT2_MOUSE
NC score	0.005842 (rank : 43)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	48	Target Neighborhood Hits	175	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

SAFB2_MOUSE
NC score	0.005299 (rank : 44)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	48	Target Neighborhood Hits	581	Shared Neighborhood Hits	4
SwissProt Accessions	Q80YR5, Q8K153	Gene names	Safb2
Domain Architecture
Description	Scaffold attachment factor B2.

LMNB2_HUMAN
NC score	0.004623 (rank : 45)	θ value	3.0926 (rank : 38)
Query Neighborhood Hits	48	Target Neighborhood Hits	723	Shared Neighborhood Hits	5
SwissProt Accessions	Q03252, O75292, Q14734, Q96DF6	Gene names	LMNB2, LMN2
Domain Architecture
Description	Lamin-B2.

TLR7_HUMAN
NC score	0.003381 (rank : 46)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	48	Target Neighborhood Hits	312	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NYK1, Q9NR98	Gene names	TLR7
Domain Architecture
Description	Toll-like receptor 7 precursor.

SRGP2_HUMAN
NC score	0.003070 (rank : 47)	θ value	6.88961 (rank : 45)
Query Neighborhood Hits	48	Target Neighborhood Hits	331	Shared Neighborhood Hits	3
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

BPAEA_HUMAN
NC score	0.000812 (rank : 48)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	48	Target Neighborhood Hits	1369	Shared Neighborhood Hits	5
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

M3K4_MOUSE
NC score	-0.000144 (rank : 49)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	48	Target Neighborhood Hits	924	Shared Neighborhood Hits	3
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

ZBTB5_MOUSE
NC score	-0.002615 (rank : 50)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	48	Target Neighborhood Hits	801	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TQG0, Q3TVR7, Q6GV09, Q8BIB5	Gene names	Zbtb5, Kiaa0354
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 5 (Transcription factor ZNF-POZ).