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Network neighborhood for query Sequence : STA5B_MOUSE

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STA5B_MOUSE
SwissProt Accessions	P42232, Q541Q5, Q60804, Q8K3Q1, Q9JKM1	Gene names	Stat5b
Domain Architecture
Description	Signal transducer and activator of transcription 5B.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

STA5A_HUMAN
θ value	0 (rank : 1)	NC score	0.993426 (rank : 4)
Query Neighborhood Hits	124	Target Neighborhood Hits	140	Shared Neighborhood Hits	95
SwissProt Accessions	P42229	Gene names	STAT5A, STAT5
Domain Architecture
Description	Signal transducer and activator of transcription 5A.

STA5A_MOUSE
θ value	0 (rank : 2)	NC score	0.995968 (rank : 3)
Query Neighborhood Hits	124	Target Neighborhood Hits	128	Shared Neighborhood Hits	103
SwissProt Accessions	P42230	Gene names	Stat5a, Mgf, Mpf
Domain Architecture
Description	Signal transducer and activator of transcription 5A (Mammary gland factor).

STA5B_HUMAN
θ value	0 (rank : 3)	NC score	0.997104 (rank : 2)
Query Neighborhood Hits	124	Target Neighborhood Hits	103	Shared Neighborhood Hits	91
SwissProt Accessions	P51692, Q8WWS8	Gene names	STAT5B
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STA5B_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	124	Target Neighborhood Hits	124	Shared Neighborhood Hits	124
SwissProt Accessions	P42232, Q541Q5, Q60804, Q8K3Q1, Q9JKM1	Gene names	Stat5b
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STAT6_MOUSE
θ value	3.64273e-126 (rank : 5)	NC score	0.944470 (rank : 5)
Query Neighborhood Hits	124	Target Neighborhood Hits	78	Shared Neighborhood Hits	20
SwissProt Accessions	P52633	Gene names	Stat6
Domain Architecture
Description	Signal transducer and transcription activator 6.

STAT6_HUMAN
θ value	1.80787e-125 (rank : 6)	NC score	0.938051 (rank : 6)
Query Neighborhood Hits	124	Target Neighborhood Hits	132	Shared Neighborhood Hits	23
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

STAT4_HUMAN
θ value	6.95003e-85 (rank : 7)	NC score	0.896637 (rank : 8)
Query Neighborhood Hits	124	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	Q14765, Q96NZ6	Gene names	STAT4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STAT4_MOUSE
θ value	1.18549e-84 (rank : 8)	NC score	0.900733 (rank : 7)
Query Neighborhood Hits	124	Target Neighborhood Hits	73	Shared Neighborhood Hits	32
SwissProt Accessions	P42228	Gene names	Stat4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STAT3_HUMAN
θ value	2.02215e-84 (rank : 9)	NC score	0.890912 (rank : 9)
Query Neighborhood Hits	124	Target Neighborhood Hits	155	Shared Neighborhood Hits	37
SwissProt Accessions	P40763, O14916, Q9BW54	Gene names	STAT3, APRF
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT3_MOUSE
θ value	2.02215e-84 (rank : 10)	NC score	0.890910 (rank : 10)
Query Neighborhood Hits	124	Target Neighborhood Hits	155	Shared Neighborhood Hits	37
SwissProt Accessions	P42227	Gene names	Stat3, Aprf
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT1_HUMAN
θ value	5.33382e-77 (rank : 11)	NC score	0.886793 (rank : 11)
Query Neighborhood Hits	124	Target Neighborhood Hits	128	Shared Neighborhood Hits	42
SwissProt Accessions	P42224	Gene names	STAT1
Domain Architecture
Description	Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84).

STAT1_MOUSE
θ value	4.99229e-75 (rank : 12)	NC score	0.885436 (rank : 12)
Query Neighborhood Hits	124	Target Neighborhood Hits	151	Shared Neighborhood Hits	48
SwissProt Accessions	P42225	Gene names	Stat1
Domain Architecture
Description	Signal transducer and activator of transcription 1.

STAT2_HUMAN
θ value	4.39379e-55 (rank : 13)	NC score	0.873324 (rank : 13)
Query Neighborhood Hits	124	Target Neighborhood Hits	99	Shared Neighborhood Hits	32
SwissProt Accessions	P52630, Q16430, Q16431	Gene names	STAT2
Domain Architecture
Description	Signal transducer and activator of transcription 2 (p113).

STAT2_MOUSE
θ value	6.7944e-48 (rank : 14)	NC score	0.818896 (rank : 14)
Query Neighborhood Hits	124	Target Neighborhood Hits	175	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

GOGB1_HUMAN
θ value	5.44631e-05 (rank : 15)	NC score	0.095980 (rank : 16)
Query Neighborhood Hits	124	Target Neighborhood Hits	2297	Shared Neighborhood Hits	105
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CP135_HUMAN
θ value	0.00298849 (rank : 16)	NC score	0.081550 (rank : 23)
Query Neighborhood Hits	124	Target Neighborhood Hits	1290	Shared Neighborhood Hits	88
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

PCNT_HUMAN
θ value	0.00390308 (rank : 17)	NC score	0.087997 (rank : 19)
Query Neighborhood Hits	124	Target Neighborhood Hits	1551	Shared Neighborhood Hits	93
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

CCD21_HUMAN
θ value	0.00869519 (rank : 18)	NC score	0.075445 (rank : 30)
Query Neighborhood Hits	124	Target Neighborhood Hits	1228	Shared Neighborhood Hits	86
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

RIMB1_MOUSE
θ value	0.00869519 (rank : 19)	NC score	0.085826 (rank : 20)
Query Neighborhood Hits	124	Target Neighborhood Hits	1376	Shared Neighborhood Hits	84
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

CI093_HUMAN
θ value	0.0148317 (rank : 20)	NC score	0.089263 (rank : 17)
Query Neighborhood Hits	124	Target Neighborhood Hits	1088	Shared Neighborhood Hits	85
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CP250_HUMAN
θ value	0.0330416 (rank : 21)	NC score	0.079374 (rank : 25)
Query Neighborhood Hits	124	Target Neighborhood Hits	1805	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

CENPF_HUMAN
θ value	0.0431538 (rank : 22)	NC score	0.075748 (rank : 29)
Query Neighborhood Hits	124	Target Neighborhood Hits	1932	Shared Neighborhood Hits	101
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CTRO_HUMAN
θ value	0.0563607 (rank : 23)	NC score	0.039312 (rank : 160)
Query Neighborhood Hits	124	Target Neighborhood Hits	2092	Shared Neighborhood Hits	90
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CF060_HUMAN
θ value	0.0736092 (rank : 24)	NC score	0.076741 (rank : 28)
Query Neighborhood Hits	124	Target Neighborhood Hits	1270	Shared Neighborhood Hits	86
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CP135_MOUSE
θ value	0.0736092 (rank : 25)	NC score	0.072163 (rank : 35)
Query Neighborhood Hits	124	Target Neighborhood Hits	1278	Shared Neighborhood Hits	89
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

DIDO1_HUMAN
θ value	0.0961366 (rank : 26)	NC score	0.046229 (rank : 153)
Query Neighborhood Hits	124	Target Neighborhood Hits	960	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

SH22A_HUMAN
θ value	0.0961366 (rank : 27)	NC score	0.116736 (rank : 15)
Query Neighborhood Hits	124	Target Neighborhood Hits	144	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

HIP1_HUMAN
θ value	0.125558 (rank : 28)	NC score	0.071667 (rank : 36)
Query Neighborhood Hits	124	Target Neighborhood Hits	1016	Shared Neighborhood Hits	78
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

CENPE_HUMAN
θ value	0.163984 (rank : 29)	NC score	0.056923 (rank : 75)
Query Neighborhood Hits	124	Target Neighborhood Hits	2060	Shared Neighborhood Hits	99
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CTRO_MOUSE
θ value	0.21417 (rank : 30)	NC score	0.040255 (rank : 158)
Query Neighborhood Hits	124	Target Neighborhood Hits	2344	Shared Neighborhood Hits	89
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

GOGA4_MOUSE
θ value	0.21417 (rank : 31)	NC score	0.077047 (rank : 27)
Query Neighborhood Hits	124	Target Neighborhood Hits	1939	Shared Neighborhood Hits	101
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

IFT74_HUMAN
θ value	0.21417 (rank : 32)	NC score	0.071617 (rank : 37)
Query Neighborhood Hits	124	Target Neighborhood Hits	949	Shared Neighborhood Hits	76
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

TFAP4_HUMAN
θ value	0.279714 (rank : 33)	NC score	0.088320 (rank : 18)
Query Neighborhood Hits	124	Target Neighborhood Hits	289	Shared Neighborhood Hits	50
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

GOGA5_MOUSE
θ value	0.365318 (rank : 34)	NC score	0.056023 (rank : 82)
Query Neighborhood Hits	124	Target Neighborhood Hits	1434	Shared Neighborhood Hits	84
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

TRIPB_HUMAN
θ value	0.365318 (rank : 35)	NC score	0.079382 (rank : 24)
Query Neighborhood Hits	124	Target Neighborhood Hits	1587	Shared Neighborhood Hits	95
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CP250_MOUSE
θ value	0.47712 (rank : 36)	NC score	0.068240 (rank : 43)
Query Neighborhood Hits	124	Target Neighborhood Hits	1583	Shared Neighborhood Hits	92
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

HSH2D_HUMAN
θ value	0.47712 (rank : 37)	NC score	0.071407 (rank : 38)
Query Neighborhood Hits	124	Target Neighborhood Hits	159	Shared Neighborhood Hits	22
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

P55G_HUMAN
θ value	0.47712 (rank : 38)	NC score	0.073224 (rank : 34)
Query Neighborhood Hits	124	Target Neighborhood Hits	451	Shared Neighborhood Hits	63
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	0.47712 (rank : 39)	NC score	0.078804 (rank : 26)
Query Neighborhood Hits	124	Target Neighborhood Hits	401	Shared Neighborhood Hits	64
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

PGBM_HUMAN
θ value	0.47712 (rank : 40)	NC score	0.001968 (rank : 188)
Query Neighborhood Hits	124	Target Neighborhood Hits	1113	Shared Neighborhood Hits	3
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

BRE1A_HUMAN
θ value	0.62314 (rank : 41)	NC score	0.071096 (rank : 39)
Query Neighborhood Hits	124	Target Neighborhood Hits	1071	Shared Neighborhood Hits	79
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

CCD11_HUMAN
θ value	0.62314 (rank : 42)	NC score	0.074290 (rank : 32)
Query Neighborhood Hits	124	Target Neighborhood Hits	822	Shared Neighborhood Hits	79
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

GOGA1_HUMAN
θ value	0.62314 (rank : 43)	NC score	0.065594 (rank : 49)
Query Neighborhood Hits	124	Target Neighborhood Hits	1222	Shared Neighborhood Hits	86
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

IFT74_MOUSE
θ value	0.62314 (rank : 44)	NC score	0.074021 (rank : 33)
Query Neighborhood Hits	124	Target Neighborhood Hits	939	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

FOXP2_HUMAN
θ value	0.813845 (rank : 45)	NC score	0.036832 (rank : 164)
Query Neighborhood Hits	124	Target Neighborhood Hits	366	Shared Neighborhood Hits	45
SwissProt Accessions	O15409, Q6ZND1, Q75MJ3, Q8IZE0, Q8N0W2, Q8N6B7, Q8N6B8, Q8NFQ1, Q8NFQ2, Q8NFQ3, Q8NFQ4, Q8TD74	Gene names	FOXP2, CAGH44, TNRC10
Domain Architecture
Description	Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat- containing gene 10 protein).

FOXP2_MOUSE
θ value	0.813845 (rank : 46)	NC score	0.037654 (rank : 163)
Query Neighborhood Hits	124	Target Neighborhood Hits	366	Shared Neighborhood Hits	44
SwissProt Accessions	P58463, Q6PD37, Q8C4F0, Q8R441	Gene names	Foxp2
Domain Architecture
Description	Forkhead box protein P2.

HAPIP_HUMAN
θ value	0.813845 (rank : 47)	NC score	0.048531 (rank : 145)
Query Neighborhood Hits	124	Target Neighborhood Hits	350	Shared Neighborhood Hits	48
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

K1C10_HUMAN
θ value	0.813845 (rank : 48)	NC score	0.022867 (rank : 174)
Query Neighborhood Hits	124	Target Neighborhood Hits	526	Shared Neighborhood Hits	64
SwissProt Accessions	P13645, Q14664, Q8N175	Gene names	KRT10
Domain Architecture
Description	Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10).

MRCKB_HUMAN
θ value	0.813845 (rank : 49)	NC score	0.029496 (rank : 168)
Query Neighborhood Hits	124	Target Neighborhood Hits	2239	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MRCKG_HUMAN
θ value	0.813845 (rank : 50)	NC score	0.024351 (rank : 172)
Query Neighborhood Hits	124	Target Neighborhood Hits	1519	Shared Neighborhood Hits	82
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

GOGA2_MOUSE
θ value	1.06291 (rank : 51)	NC score	0.081775 (rank : 22)
Query Neighborhood Hits	124	Target Neighborhood Hits	944	Shared Neighborhood Hits	87
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

MACF1_HUMAN
θ value	1.06291 (rank : 52)	NC score	0.054772 (rank : 97)
Query Neighborhood Hits	124	Target Neighborhood Hits	1341	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	1.06291 (rank : 53)	NC score	0.062719 (rank : 57)
Query Neighborhood Hits	124	Target Neighborhood Hits	1321	Shared Neighborhood Hits	92
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MLL2_HUMAN
θ value	1.06291 (rank : 54)	NC score	0.048200 (rank : 147)
Query Neighborhood Hits	124	Target Neighborhood Hits	1788	Shared Neighborhood Hits	66
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MY18A_HUMAN
θ value	1.06291 (rank : 55)	NC score	0.049082 (rank : 143)
Query Neighborhood Hits	124	Target Neighborhood Hits	1929	Shared Neighborhood Hits	95
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CCD45_MOUSE
θ value	1.38821 (rank : 56)	NC score	0.068257 (rank : 42)
Query Neighborhood Hits	124	Target Neighborhood Hits	663	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CHIN_HUMAN
θ value	1.38821 (rank : 57)	NC score	0.023127 (rank : 173)
Query Neighborhood Hits	124	Target Neighborhood Hits	227	Shared Neighborhood Hits	18
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

GOGA4_HUMAN
θ value	1.38821 (rank : 58)	NC score	0.067788 (rank : 44)
Query Neighborhood Hits	124	Target Neighborhood Hits	2034	Shared Neighborhood Hits	99
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

HSH2D_MOUSE
θ value	1.38821 (rank : 59)	NC score	0.084913 (rank : 21)
Query Neighborhood Hits	124	Target Neighborhood Hits	124	Shared Neighborhood Hits	25
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

TRHY_HUMAN
θ value	1.38821 (rank : 60)	NC score	0.063135 (rank : 55)
Query Neighborhood Hits	124	Target Neighborhood Hits	1385	Shared Neighborhood Hits	83
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

XE7_HUMAN
θ value	1.38821 (rank : 61)	NC score	0.054701 (rank : 98)
Query Neighborhood Hits	124	Target Neighborhood Hits	738	Shared Neighborhood Hits	71
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

BRE1A_MOUSE
θ value	1.81305 (rank : 62)	NC score	0.065020 (rank : 52)
Query Neighborhood Hits	124	Target Neighborhood Hits	1025	Shared Neighborhood Hits	80
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

DNMBP_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.017247 (rank : 181)
Query Neighborhood Hits	124	Target Neighborhood Hits	413	Shared Neighborhood Hits	25
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

K22E_HUMAN
θ value	1.81305 (rank : 64)	NC score	0.020481 (rank : 178)
Query Neighborhood Hits	124	Target Neighborhood Hits	515	Shared Neighborhood Hits	58
SwissProt Accessions	P35908	Gene names	KRT2A, KRT2E
Domain Architecture
Description	Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (K2e) (CK 2e).

M4K4_HUMAN
θ value	1.81305 (rank : 65)	NC score	0.016016 (rank : 182)
Query Neighborhood Hits	124	Target Neighborhood Hits	1589	Shared Neighborhood Hits	73
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

PCQAP_MOUSE
θ value	1.81305 (rank : 66)	NC score	0.052990 (rank : 108)
Query Neighborhood Hits	124	Target Neighborhood Hits	506	Shared Neighborhood Hits	44
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

SLK_HUMAN
θ value	1.81305 (rank : 67)	NC score	0.018118 (rank : 179)
Query Neighborhood Hits	124	Target Neighborhood Hits	1775	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

SWP70_MOUSE
θ value	1.81305 (rank : 68)	NC score	0.057882 (rank : 69)
Query Neighborhood Hits	124	Target Neighborhood Hits	1097	Shared Neighborhood Hits	80
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

BAIP2_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.017985 (rank : 180)
Query Neighborhood Hits	124	Target Neighborhood Hits	192	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

BPAEA_MOUSE
θ value	2.36792 (rank : 70)	NC score	0.056584 (rank : 77)
Query Neighborhood Hits	124	Target Neighborhood Hits	1480	Shared Neighborhood Hits	90
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CASP_HUMAN
θ value	2.36792 (rank : 71)	NC score	0.052548 (rank : 112)
Query Neighborhood Hits	124	Target Neighborhood Hits	1131	Shared Neighborhood Hits	78
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CHIN_MOUSE
θ value	2.36792 (rank : 72)	NC score	0.020533 (rank : 177)
Query Neighborhood Hits	124	Target Neighborhood Hits	229	Shared Neighborhood Hits	17
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

HIP1R_HUMAN
θ value	2.36792 (rank : 73)	NC score	0.065121 (rank : 51)
Query Neighborhood Hits	124	Target Neighborhood Hits	809	Shared Neighborhood Hits	78
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

HIP1R_MOUSE
θ value	2.36792 (rank : 74)	NC score	0.063057 (rank : 56)
Query Neighborhood Hits	124	Target Neighborhood Hits	959	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

INCE_HUMAN
θ value	2.36792 (rank : 75)	NC score	0.058428 (rank : 68)
Query Neighborhood Hits	124	Target Neighborhood Hits	978	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

MYH6_HUMAN
θ value	2.36792 (rank : 76)	NC score	0.039803 (rank : 159)
Query Neighborhood Hits	124	Target Neighborhood Hits	1426	Shared Neighborhood Hits	80
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

RUFY2_HUMAN
θ value	2.36792 (rank : 77)	NC score	0.046857 (rank : 149)
Query Neighborhood Hits	124	Target Neighborhood Hits	1208	Shared Neighborhood Hits	86
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

BIN1_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.014954 (rank : 183)
Query Neighborhood Hits	124	Target Neighborhood Hits	335	Shared Neighborhood Hits	19
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

EVPL_MOUSE
θ value	3.0926 (rank : 79)	NC score	0.053031 (rank : 107)
Query Neighborhood Hits	124	Target Neighborhood Hits	952	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

MYH7_HUMAN
θ value	3.0926 (rank : 80)	NC score	0.039128 (rank : 161)
Query Neighborhood Hits	124	Target Neighborhood Hits	1559	Shared Neighborhood Hits	84
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

P85A_HUMAN
θ value	3.0926 (rank : 81)	NC score	0.057320 (rank : 72)
Query Neighborhood Hits	124	Target Neighborhood Hits	479	Shared Neighborhood Hits	62
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
θ value	3.0926 (rank : 82)	NC score	0.055557 (rank : 91)
Query Neighborhood Hits	124	Target Neighborhood Hits	435	Shared Neighborhood Hits	54
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

PLEC1_HUMAN
θ value	3.0926 (rank : 83)	NC score	0.053571 (rank : 103)
Query Neighborhood Hits	124	Target Neighborhood Hits	1326	Shared Neighborhood Hits	90
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

SPTA1_HUMAN
θ value	3.0926 (rank : 84)	NC score	0.041668 (rank : 156)
Query Neighborhood Hits	124	Target Neighborhood Hits	748	Shared Neighborhood Hits	74
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

TUFT1_HUMAN
θ value	3.0926 (rank : 85)	NC score	0.057418 (rank : 71)
Query Neighborhood Hits	124	Target Neighborhood Hits	686	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

CNTRB_HUMAN
θ value	4.03905 (rank : 86)	NC score	0.067049 (rank : 45)
Query Neighborhood Hits	124	Target Neighborhood Hits	690	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CUTL1_HUMAN
θ value	4.03905 (rank : 87)	NC score	0.046592 (rank : 151)
Query Neighborhood Hits	124	Target Neighborhood Hits	1574	Shared Neighborhood Hits	81
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

EEA1_HUMAN
θ value	4.03905 (rank : 88)	NC score	0.063335 (rank : 54)
Query Neighborhood Hits	124	Target Neighborhood Hits	1796	Shared Neighborhood Hits	95
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

EVC_MOUSE
θ value	4.03905 (rank : 89)	NC score	0.026213 (rank : 169)
Query Neighborhood Hits	124	Target Neighborhood Hits	80	Shared Neighborhood Hits	17
SwissProt Accessions	P57680	Gene names	Evc
Domain Architecture	No domain graphic available
Description	Ellis-van Creveld syndrome protein homolog.

HMMR_MOUSE
θ value	4.03905 (rank : 90)	NC score	0.060867 (rank : 62)
Query Neighborhood Hits	124	Target Neighborhood Hits	1178	Shared Neighborhood Hits	89
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

K1683_HUMAN
θ value	4.03905 (rank : 91)	NC score	0.040950 (rank : 157)
Query Neighborhood Hits	124	Target Neighborhood Hits	240	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

KIF4A_MOUSE
θ value	4.03905 (rank : 92)	NC score	0.036727 (rank : 165)
Query Neighborhood Hits	124	Target Neighborhood Hits	1033	Shared Neighborhood Hits	80
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

MED12_HUMAN
θ value	4.03905 (rank : 93)	NC score	0.044625 (rank : 154)
Query Neighborhood Hits	124	Target Neighborhood Hits	262	Shared Neighborhood Hits	37
SwissProt Accessions	Q93074, O15410, O75557, Q9UHV6, Q9UND7	Gene names	MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 12 (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (OPA-containing protein) (Trinucleotide repeat-containing gene 11 protein).

P85B_MOUSE
θ value	4.03905 (rank : 94)	NC score	0.069419 (rank : 41)
Query Neighborhood Hits	124	Target Neighborhood Hits	519	Shared Neighborhood Hits	75
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PPT2_HUMAN
θ value	4.03905 (rank : 95)	NC score	0.021633 (rank : 175)
Query Neighborhood Hits	124	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UMR5, O14799, Q0P6K0, Q5JP13, Q5JP14, Q5JQF0, Q5SSX4, Q5SSX5, Q5SSX6, Q5STJ4, Q5STJ5, Q5STJ6, Q6FI80, Q99945	Gene names	PPT2
Domain Architecture
Description	Lysosomal thioesterase PPT2 precursor (EC 3.1.2.-) (PPT-2) (S- thioesterase G14).

RABE2_MOUSE
θ value	4.03905 (rank : 96)	NC score	0.060567 (rank : 64)
Query Neighborhood Hits	124	Target Neighborhood Hits	598	Shared Neighborhood Hits	79
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

ANR26_HUMAN
θ value	5.27518 (rank : 97)	NC score	0.051373 (rank : 122)
Query Neighborhood Hits	124	Target Neighborhood Hits	1614	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CASP_MOUSE
θ value	5.27518 (rank : 98)	NC score	0.050295 (rank : 138)
Query Neighborhood Hits	124	Target Neighborhood Hits	1152	Shared Neighborhood Hits	77
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CR034_HUMAN
θ value	5.27518 (rank : 99)	NC score	0.054406 (rank : 101)
Query Neighborhood Hits	124	Target Neighborhood Hits	538	Shared Neighborhood Hits	66
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

CUTL1_MOUSE
θ value	5.27518 (rank : 100)	NC score	0.046384 (rank : 152)
Query Neighborhood Hits	124	Target Neighborhood Hits	1620	Shared Neighborhood Hits	83
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

GRAP1_MOUSE
θ value	5.27518 (rank : 101)	NC score	0.055870 (rank : 85)
Query Neighborhood Hits	124	Target Neighborhood Hits	1234	Shared Neighborhood Hits	87
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

LRSM1_HUMAN
θ value	5.27518 (rank : 102)	NC score	0.043719 (rank : 155)
Query Neighborhood Hits	124	Target Neighborhood Hits	1078	Shared Neighborhood Hits	79
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MLL3_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.010521 (rank : 185)
Query Neighborhood Hits	124	Target Neighborhood Hits	1644	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MY18A_MOUSE
θ value	5.27518 (rank : 104)	NC score	0.047074 (rank : 148)
Query Neighborhood Hits	124	Target Neighborhood Hits	1989	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NUMA1_HUMAN
θ value	5.27518 (rank : 105)	NC score	0.066802 (rank : 46)
Query Neighborhood Hits	124	Target Neighborhood Hits	1523	Shared Neighborhood Hits	90
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

P85B_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.070009 (rank : 40)
Query Neighborhood Hits	124	Target Neighborhood Hits	543	Shared Neighborhood Hits	76
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

SOCS4_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.036679 (rank : 166)
Query Neighborhood Hits	124	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXH5	Gene names	SOCS4, SOCS7
Domain Architecture
Description	Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7).

SOCS4_MOUSE
θ value	5.27518 (rank : 108)	NC score	0.039022 (rank : 162)
Query Neighborhood Hits	124	Target Neighborhood Hits	69	Shared Neighborhood Hits	19
SwissProt Accessions	Q91ZA6	Gene names	Socs4, Socs7
Domain Architecture
Description	Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7).

WNK2_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.003403 (rank : 187)
Query Neighborhood Hits	124	Target Neighborhood Hits	1407	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

AKAP9_HUMAN
θ value	6.88961 (rank : 110)	NC score	0.058515 (rank : 67)
Query Neighborhood Hits	124	Target Neighborhood Hits	1710	Shared Neighborhood Hits	97
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

ANR26_MOUSE
θ value	6.88961 (rank : 111)	NC score	0.048491 (rank : 146)
Query Neighborhood Hits	124	Target Neighborhood Hits	1554	Shared Neighborhood Hits	91
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

APOA4_MOUSE
θ value	6.88961 (rank : 112)	NC score	0.046631 (rank : 150)
Query Neighborhood Hits	124	Target Neighborhood Hits	435	Shared Neighborhood Hits	51
SwissProt Accessions	P06728	Gene names	Apoa4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

BAZ1B_MOUSE
θ value	6.88961 (rank : 113)	NC score	0.020752 (rank : 176)
Query Neighborhood Hits	124	Target Neighborhood Hits	394	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

RAI14_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.034247 (rank : 167)
Query Neighborhood Hits	124	Target Neighborhood Hits	1367	Shared Neighborhood Hits	75
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

SRMS_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.001748 (rank : 189)
Query Neighborhood Hits	124	Target Neighborhood Hits	946	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

APOE_MOUSE
θ value	8.99809 (rank : 116)	NC score	0.048739 (rank : 144)
Query Neighborhood Hits	124	Target Neighborhood Hits	319	Shared Neighborhood Hits	51
SwissProt Accessions	P08226	Gene names	Apoe
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

CCD46_HUMAN
θ value	8.99809 (rank : 117)	NC score	0.052843 (rank : 109)
Query Neighborhood Hits	124	Target Neighborhood Hits	1430	Shared Neighborhood Hits	92
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

HMMR_HUMAN
θ value	8.99809 (rank : 118)	NC score	0.066113 (rank : 48)
Query Neighborhood Hits	124	Target Neighborhood Hits	1082	Shared Neighborhood Hits	84
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

KTN1_HUMAN
θ value	8.99809 (rank : 119)	NC score	0.066276 (rank : 47)
Query Neighborhood Hits	124	Target Neighborhood Hits	1197	Shared Neighborhood Hits	88
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

PAR14_MOUSE
θ value	8.99809 (rank : 120)	NC score	0.008090 (rank : 186)
Query Neighborhood Hits	124	Target Neighborhood Hits	113	Shared Neighborhood Hits	13
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

SH22A_MOUSE
θ value	8.99809 (rank : 121)	NC score	0.063831 (rank : 53)
Query Neighborhood Hits	124	Target Neighborhood Hits	179	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

SOCS5_HUMAN
θ value	8.99809 (rank : 122)	NC score	0.025754 (rank : 171)
Query Neighborhood Hits	124	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	O75159, Q8IYZ4	Gene names	SOCS5, CIS6, CISH5, CISH6, KIAA0671
Domain Architecture
Description	Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5) (Cytokine-inducible SH2 protein 6) (CIS-6).

SOCS5_MOUSE
θ value	8.99809 (rank : 123)	NC score	0.026034 (rank : 170)
Query Neighborhood Hits	124	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	O54928	Gene names	Socs5, Cish5
Domain Architecture
Description	Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5).

UCHL5_HUMAN
θ value	8.99809 (rank : 124)	NC score	0.010599 (rank : 184)
Query Neighborhood Hits	124	Target Neighborhood Hits	35	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y5K5, Q5LJA6, Q5LJA7, Q8TBS4, Q96BJ9, Q9H1W5, Q9P0I3, Q9UQN2	Gene names	UCHL5, UCH37
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase isozyme L5 (EC 3.4.19.12) (UCH- L5) (Ubiquitin thioesterase L5) (Ubiquitin C-terminal hydrolase UCH37).

AZI1_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.050536 (rank : 131)
Query Neighborhood Hits	124	Target Neighborhood Hits	1000	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

AZI1_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.052822 (rank : 110)
Query Neighborhood Hits	124	Target Neighborhood Hits	990	Shared Neighborhood Hits	80
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BRE1B_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.054926 (rank : 96)
Query Neighborhood Hits	124	Target Neighborhood Hits	970	Shared Neighborhood Hits	76
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

C102B_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.050053 (rank : 141)
Query Neighborhood Hits	124	Target Neighborhood Hits	542	Shared Neighborhood Hits	65
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

CCD11_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.052454 (rank : 113)
Query Neighborhood Hits	124	Target Neighborhood Hits	498	Shared Neighborhood Hits	61
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD13_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.050342 (rank : 136)
Query Neighborhood Hits	124	Target Neighborhood Hits	721	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

CCD19_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.059781 (rank : 65)
Query Neighborhood Hits	124	Target Neighborhood Hits	639	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CCD21_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.055407 (rank : 94)
Query Neighborhood Hits	124	Target Neighborhood Hits	1135	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD27_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.074461 (rank : 31)
Query Neighborhood Hits	124	Target Neighborhood Hits	594	Shared Neighborhood Hits	72
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD27_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.060993 (rank : 61)
Query Neighborhood Hits	124	Target Neighborhood Hits	461	Shared Neighborhood Hits	57
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD39_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.050462 (rank : 133)
Query Neighborhood Hits	124	Target Neighborhood Hits	868	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD39_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.056253 (rank : 80)
Query Neighborhood Hits	124	Target Neighborhood Hits	1026	Shared Neighborhood Hits	83
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD91_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.052778 (rank : 111)
Query Neighborhood Hits	124	Target Neighborhood Hits	868	Shared Neighborhood Hits	73
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CCHCR_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.055675 (rank : 90)
Query Neighborhood Hits	124	Target Neighborhood Hits	717	Shared Neighborhood Hits	79
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CCHCR_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.050859 (rank : 129)
Query Neighborhood Hits	124	Target Neighborhood Hits	932	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CE152_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.050146 (rank : 140)
Query Neighborhood Hits	124	Target Neighborhood Hits	976	Shared Neighborhood Hits	78
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CE290_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.055761 (rank : 89)
Query Neighborhood Hits	124	Target Neighborhood Hits	1553	Shared Neighborhood Hits	91
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CEP55_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.050019 (rank : 142)
Query Neighborhood Hits	124	Target Neighborhood Hits	504	Shared Neighborhood Hits	66
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

CEP63_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.051337 (rank : 124)
Query Neighborhood Hits	124	Target Neighborhood Hits	1005	Shared Neighborhood Hits	82
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CING_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.051367 (rank : 123)
Query Neighborhood Hits	124	Target Neighborhood Hits	1275	Shared Neighborhood Hits	85
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CING_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.055839 (rank : 87)
Query Neighborhood Hits	124	Target Neighborhood Hits	1432	Shared Neighborhood Hits	92
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CJ118_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.051753 (rank : 121)
Query Neighborhood Hits	124	Target Neighborhood Hits	1132	Shared Neighborhood Hits	79
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CK5P2_MOUSE
θ value	θ > 10 (rank : 147)	NC score	0.050943 (rank : 127)
Query Neighborhood Hits	124	Target Neighborhood Hits	1151	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CKAP4_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.050747 (rank : 130)
Query Neighborhood Hits	124	Target Neighborhood Hits	596	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CNTRB_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.052243 (rank : 116)
Query Neighborhood Hits	124	Target Neighborhood Hits	1029	Shared Neighborhood Hits	80
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CROCC_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.056374 (rank : 78)
Query Neighborhood Hits	124	Target Neighborhood Hits	1409	Shared Neighborhood Hits	84
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CROCC_MOUSE
θ value	θ > 10 (rank : 151)	NC score	0.057534 (rank : 70)
Query Neighborhood Hits	124	Target Neighborhood Hits	1460	Shared Neighborhood Hits	83
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

DESP_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.051021 (rank : 125)
Query Neighborhood Hits	124	Target Neighborhood Hits	1470	Shared Neighborhood Hits	88
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

EEA1_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.055867 (rank : 86)
Query Neighborhood Hits	124	Target Neighborhood Hits	1637	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

FYCO1_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.053965 (rank : 102)
Query Neighborhood Hits	124	Target Neighborhood Hits	1149	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

FYCO1_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.052272 (rank : 115)
Query Neighborhood Hits	124	Target Neighborhood Hits	1059	Shared Neighborhood Hits	88
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

GCC2_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.056010 (rank : 83)
Query Neighborhood Hits	124	Target Neighborhood Hits	1558	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GCC2_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.052093 (rank : 117)
Query Neighborhood Hits	124	Target Neighborhood Hits	1619	Shared Neighborhood Hits	92
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GOGA1_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.060591 (rank : 63)
Query Neighborhood Hits	124	Target Neighborhood Hits	994	Shared Neighborhood Hits	84
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA2_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.062538 (rank : 58)
Query Neighborhood Hits	124	Target Neighborhood Hits	856	Shared Neighborhood Hits	77
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

GOGA3_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.050902 (rank : 128)
Query Neighborhood Hits	124	Target Neighborhood Hits	1317	Shared Neighborhood Hits	84
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

GOGA3_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.052023 (rank : 118)
Query Neighborhood Hits	124	Target Neighborhood Hits	1437	Shared Neighborhood Hits	85
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

GOGA5_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.051956 (rank : 119)
Query Neighborhood Hits	124	Target Neighborhood Hits	1168	Shared Neighborhood Hits	83
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

GOGA6_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.053436 (rank : 106)
Query Neighborhood Hits	124	Target Neighborhood Hits	1007	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

GRAP1_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.053452 (rank : 105)
Query Neighborhood Hits	124	Target Neighborhood Hits	944	Shared Neighborhood Hits	80
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

HOOK1_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.050491 (rank : 132)
Query Neighborhood Hits	124	Target Neighborhood Hits	942	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

INVO_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.055883 (rank : 84)
Query Neighborhood Hits	124	Target Neighborhood Hits	636	Shared Neighborhood Hits	65
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

KTN1_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.053506 (rank : 104)
Query Neighborhood Hits	124	Target Neighborhood Hits	1324	Shared Neighborhood Hits	83
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

LRC45_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.050442 (rank : 134)
Query Neighborhood Hits	124	Target Neighborhood Hits	933	Shared Neighborhood Hits	83
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

NAF1_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.055770 (rank : 88)
Query Neighborhood Hits	124	Target Neighborhood Hits	937	Shared Neighborhood Hits	83
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NAF1_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.056203 (rank : 81)
Query Neighborhood Hits	124	Target Neighborhood Hits	852	Shared Neighborhood Hits	83
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NEMO_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.055551 (rank : 92)
Query Neighborhood Hits	124	Target Neighborhood Hits	658	Shared Neighborhood Hits	71
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

NIN_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.058665 (rank : 66)
Query Neighborhood Hits	124	Target Neighborhood Hits	1416	Shared Neighborhood Hits	86
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

NIN_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.055435 (rank : 93)
Query Neighborhood Hits	124	Target Neighborhood Hits	1376	Shared Neighborhood Hits	84
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

PCNT_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.061990 (rank : 59)
Query Neighborhood Hits	124	Target Neighborhood Hits	1207	Shared Neighborhood Hits	86
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PEPL_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.050323 (rank : 137)
Query Neighborhood Hits	124	Target Neighborhood Hits	1141	Shared Neighborhood Hits	78
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PININ_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.050417 (rank : 135)
Query Neighborhood Hits	124	Target Neighborhood Hits	753	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

RABE1_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.054570 (rank : 99)
Query Neighborhood Hits	124	Target Neighborhood Hits	1104	Shared Neighborhood Hits	85
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.055081 (rank : 95)
Query Neighborhood Hits	124	Target Neighborhood Hits	1105	Shared Neighborhood Hits	84
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

RAD50_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.057208 (rank : 73)
Query Neighborhood Hits	124	Target Neighborhood Hits	1317	Shared Neighborhood Hits	85
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RAD50_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.054537 (rank : 100)
Query Neighborhood Hits	124	Target Neighborhood Hits	1366	Shared Neighborhood Hits	91
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RBP24_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.056353 (rank : 79)
Query Neighborhood Hits	124	Target Neighborhood Hits	1559	Shared Neighborhood Hits	92
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

REST_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.052382 (rank : 114)
Query Neighborhood Hits	124	Target Neighborhood Hits	1605	Shared Neighborhood Hits	84
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

REST_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.061006 (rank : 60)
Query Neighborhood Hits	124	Target Neighborhood Hits	1506	Shared Neighborhood Hits	84
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RIMB1_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.057034 (rank : 74)
Query Neighborhood Hits	124	Target Neighborhood Hits	1479	Shared Neighborhood Hits	77
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RPGR1_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.056662 (rank : 76)
Query Neighborhood Hits	124	Target Neighborhood Hits	578	Shared Neighborhood Hits	67
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SAS6_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.051938 (rank : 120)
Query Neighborhood Hits	124	Target Neighborhood Hits	931	Shared Neighborhood Hits	84
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

SYNE1_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.050968 (rank : 126)
Query Neighborhood Hits	124	Target Neighborhood Hits	1484	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TMF1_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.050231 (rank : 139)
Query Neighborhood Hits	124	Target Neighborhood Hits	987	Shared Neighborhood Hits	74
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TPR_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.065446 (rank : 50)
Query Neighborhood Hits	124	Target Neighborhood Hits	1921	Shared Neighborhood Hits	93
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

Hits sorted by NC score

STA5B_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	124	Target Neighborhood Hits	124	Shared Neighborhood Hits	124
SwissProt Accessions	P42232, Q541Q5, Q60804, Q8K3Q1, Q9JKM1	Gene names	Stat5b
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STA5B_HUMAN
NC score	0.997104 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	124	Target Neighborhood Hits	103	Shared Neighborhood Hits	91
SwissProt Accessions	P51692, Q8WWS8	Gene names	STAT5B
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STA5A_MOUSE
NC score	0.995968 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	124	Target Neighborhood Hits	128	Shared Neighborhood Hits	103
SwissProt Accessions	P42230	Gene names	Stat5a, Mgf, Mpf
Domain Architecture
Description	Signal transducer and activator of transcription 5A (Mammary gland factor).

STA5A_HUMAN
NC score	0.993426 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	124	Target Neighborhood Hits	140	Shared Neighborhood Hits	95
SwissProt Accessions	P42229	Gene names	STAT5A, STAT5
Domain Architecture
Description	Signal transducer and activator of transcription 5A.

STAT6_MOUSE
NC score	0.944470 (rank : 5)	θ value	3.64273e-126 (rank : 5)
Query Neighborhood Hits	124	Target Neighborhood Hits	78	Shared Neighborhood Hits	20
SwissProt Accessions	P52633	Gene names	Stat6
Domain Architecture
Description	Signal transducer and transcription activator 6.

STAT6_HUMAN
NC score	0.938051 (rank : 6)	θ value	1.80787e-125 (rank : 6)
Query Neighborhood Hits	124	Target Neighborhood Hits	132	Shared Neighborhood Hits	23
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

STAT4_MOUSE
NC score	0.900733 (rank : 7)	θ value	1.18549e-84 (rank : 8)
Query Neighborhood Hits	124	Target Neighborhood Hits	73	Shared Neighborhood Hits	32
SwissProt Accessions	P42228	Gene names	Stat4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STAT4_HUMAN
NC score	0.896637 (rank : 8)	θ value	6.95003e-85 (rank : 7)
Query Neighborhood Hits	124	Target Neighborhood Hits	91	Shared Neighborhood Hits	34
SwissProt Accessions	Q14765, Q96NZ6	Gene names	STAT4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STAT3_HUMAN
NC score	0.890912 (rank : 9)	θ value	2.02215e-84 (rank : 9)
Query Neighborhood Hits	124	Target Neighborhood Hits	155	Shared Neighborhood Hits	37
SwissProt Accessions	P40763, O14916, Q9BW54	Gene names	STAT3, APRF
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT3_MOUSE
NC score	0.890910 (rank : 10)	θ value	2.02215e-84 (rank : 10)
Query Neighborhood Hits	124	Target Neighborhood Hits	155	Shared Neighborhood Hits	37
SwissProt Accessions	P42227	Gene names	Stat3, Aprf
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT1_HUMAN
NC score	0.886793 (rank : 11)	θ value	5.33382e-77 (rank : 11)
Query Neighborhood Hits	124	Target Neighborhood Hits	128	Shared Neighborhood Hits	42
SwissProt Accessions	P42224	Gene names	STAT1
Domain Architecture
Description	Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84).

STAT1_MOUSE
NC score	0.885436 (rank : 12)	θ value	4.99229e-75 (rank : 12)
Query Neighborhood Hits	124	Target Neighborhood Hits	151	Shared Neighborhood Hits	48
SwissProt Accessions	P42225	Gene names	Stat1
Domain Architecture
Description	Signal transducer and activator of transcription 1.

STAT2_HUMAN
NC score	0.873324 (rank : 13)	θ value	4.39379e-55 (rank : 13)
Query Neighborhood Hits	124	Target Neighborhood Hits	99	Shared Neighborhood Hits	32
SwissProt Accessions	P52630, Q16430, Q16431	Gene names	STAT2
Domain Architecture
Description	Signal transducer and activator of transcription 2 (p113).

STAT2_MOUSE
NC score	0.818896 (rank : 14)	θ value	6.7944e-48 (rank : 14)
Query Neighborhood Hits	124	Target Neighborhood Hits	175	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

SH22A_HUMAN
NC score	0.116736 (rank : 15)	θ value	0.0961366 (rank : 27)
Query Neighborhood Hits	124	Target Neighborhood Hits	144	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

GOGB1_HUMAN
NC score	0.095980 (rank : 16)	θ value	5.44631e-05 (rank : 15)
Query Neighborhood Hits	124	Target Neighborhood Hits	2297	Shared Neighborhood Hits	105
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CI093_HUMAN
NC score	0.089263 (rank : 17)	θ value	0.0148317 (rank : 20)
Query Neighborhood Hits	124	Target Neighborhood Hits	1088	Shared Neighborhood Hits	85
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

TFAP4_HUMAN
NC score	0.088320 (rank : 18)	θ value	0.279714 (rank : 33)
Query Neighborhood Hits	124	Target Neighborhood Hits	289	Shared Neighborhood Hits	50
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

PCNT_HUMAN
NC score	0.087997 (rank : 19)	θ value	0.00390308 (rank : 17)
Query Neighborhood Hits	124	Target Neighborhood Hits	1551	Shared Neighborhood Hits	93
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

RIMB1_MOUSE
NC score	0.085826 (rank : 20)	θ value	0.00869519 (rank : 19)
Query Neighborhood Hits	124	Target Neighborhood Hits	1376	Shared Neighborhood Hits	84
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

HSH2D_MOUSE
NC score	0.084913 (rank : 21)	θ value	1.38821 (rank : 59)
Query Neighborhood Hits	124	Target Neighborhood Hits	124	Shared Neighborhood Hits	25
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

GOGA2_MOUSE
NC score	0.081775 (rank : 22)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	124	Target Neighborhood Hits	944	Shared Neighborhood Hits	87
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

CP135_HUMAN
NC score	0.081550 (rank : 23)	θ value	0.00298849 (rank : 16)
Query Neighborhood Hits	124	Target Neighborhood Hits	1290	Shared Neighborhood Hits	88
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

TRIPB_HUMAN
NC score	0.079382 (rank : 24)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	124	Target Neighborhood Hits	1587	Shared Neighborhood Hits	95
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CP250_HUMAN
NC score	0.079374 (rank : 25)	θ value	0.0330416 (rank : 21)
Query Neighborhood Hits	124	Target Neighborhood Hits	1805	Shared Neighborhood Hits	96
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

P55G_MOUSE
NC score	0.078804 (rank : 26)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	124	Target Neighborhood Hits	401	Shared Neighborhood Hits	64
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

GOGA4_MOUSE
NC score	0.077047 (rank : 27)	θ value	0.21417 (rank : 31)
Query Neighborhood Hits	124	Target Neighborhood Hits	1939	Shared Neighborhood Hits	101
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

CF060_HUMAN
NC score	0.076741 (rank : 28)	θ value	0.0736092 (rank : 24)
Query Neighborhood Hits	124	Target Neighborhood Hits	1270	Shared Neighborhood Hits	86
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CENPF_HUMAN
NC score	0.075748 (rank : 29)	θ value	0.0431538 (rank : 22)
Query Neighborhood Hits	124	Target Neighborhood Hits	1932	Shared Neighborhood Hits	101
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CCD21_HUMAN
NC score	0.075445 (rank : 30)	θ value	0.00869519 (rank : 18)
Query Neighborhood Hits	124	Target Neighborhood Hits	1228	Shared Neighborhood Hits	86
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD27_HUMAN
NC score	0.074461 (rank : 31)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	124	Target Neighborhood Hits	594	Shared Neighborhood Hits	72
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD11_HUMAN
NC score	0.074290 (rank : 32)	θ value	0.62314 (rank : 42)
Query Neighborhood Hits	124	Target Neighborhood Hits	822	Shared Neighborhood Hits	79
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

IFT74_MOUSE
NC score	0.074021 (rank : 33)	θ value	0.62314 (rank : 44)
Query Neighborhood Hits	124	Target Neighborhood Hits	939	Shared Neighborhood Hits	78
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

P55G_HUMAN
NC score	0.073224 (rank : 34)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	124	Target Neighborhood Hits	451	Shared Neighborhood Hits	63
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

CP135_MOUSE
NC score	0.072163 (rank : 35)	θ value	0.0736092 (rank : 25)
Query Neighborhood Hits	124	Target Neighborhood Hits	1278	Shared Neighborhood Hits	89
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

HIP1_HUMAN
NC score	0.071667 (rank : 36)	θ value	0.125558 (rank : 28)
Query Neighborhood Hits	124	Target Neighborhood Hits	1016	Shared Neighborhood Hits	78
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

IFT74_HUMAN
NC score	0.071617 (rank : 37)	θ value	0.21417 (rank : 32)
Query Neighborhood Hits	124	Target Neighborhood Hits	949	Shared Neighborhood Hits	76
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

HSH2D_HUMAN
NC score	0.071407 (rank : 38)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	124	Target Neighborhood Hits	159	Shared Neighborhood Hits	22
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

BRE1A_HUMAN
NC score	0.071096 (rank : 39)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	124	Target Neighborhood Hits	1071	Shared Neighborhood Hits	79
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

P85B_HUMAN
NC score	0.070009 (rank : 40)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	124	Target Neighborhood Hits	543	Shared Neighborhood Hits	76
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
NC score	0.069419 (rank : 41)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	124	Target Neighborhood Hits	519	Shared Neighborhood Hits	75
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

CCD45_MOUSE
NC score	0.068257 (rank : 42)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	124	Target Neighborhood Hits	663	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CP250_MOUSE
NC score	0.068240 (rank : 43)	θ value	0.47712 (rank : 36)
Query Neighborhood Hits	124	Target Neighborhood Hits	1583	Shared Neighborhood Hits	92
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

GOGA4_HUMAN
NC score	0.067788 (rank : 44)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	124	Target Neighborhood Hits	2034	Shared Neighborhood Hits	99
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

CNTRB_HUMAN
NC score	0.067049 (rank : 45)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	124	Target Neighborhood Hits	690	Shared Neighborhood Hits	78
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

NUMA1_HUMAN
NC score	0.066802 (rank : 46)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	124	Target Neighborhood Hits	1523	Shared Neighborhood Hits	90
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

KTN1_HUMAN
NC score	0.066276 (rank : 47)	θ value	8.99809 (rank : 119)
Query Neighborhood Hits	124	Target Neighborhood Hits	1197	Shared Neighborhood Hits	88
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

HMMR_HUMAN
NC score	0.066113 (rank : 48)	θ value	8.99809 (rank : 118)
Query Neighborhood Hits	124	Target Neighborhood Hits	1082	Shared Neighborhood Hits	84
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

GOGA1_HUMAN
NC score	0.065594 (rank : 49)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	124	Target Neighborhood Hits	1222	Shared Neighborhood Hits	86
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

TPR_HUMAN
NC score	0.065446 (rank : 50)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	124	Target Neighborhood Hits	1921	Shared Neighborhood Hits	93
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

HIP1R_HUMAN
NC score	0.065121 (rank : 51)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	124	Target Neighborhood Hits	809	Shared Neighborhood Hits	78
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

BRE1A_MOUSE
NC score	0.065020 (rank : 52)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	124	Target Neighborhood Hits	1025	Shared Neighborhood Hits	80
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

SH22A_MOUSE
NC score	0.063831 (rank : 53)	θ value	8.99809 (rank : 121)
Query Neighborhood Hits	124	Target Neighborhood Hits	179	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

EEA1_HUMAN
NC score	0.063335 (rank : 54)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	124	Target Neighborhood Hits	1796	Shared Neighborhood Hits	95
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

TRHY_HUMAN
NC score	0.063135 (rank : 55)	θ value	1.38821 (rank : 60)
Query Neighborhood Hits	124	Target Neighborhood Hits	1385	Shared Neighborhood Hits	83
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

HIP1R_MOUSE
NC score	0.063057 (rank : 56)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	124	Target Neighborhood Hits	959	Shared Neighborhood Hits	84
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

MACF4_HUMAN
NC score	0.062719 (rank : 57)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	124	Target Neighborhood Hits	1321	Shared Neighborhood Hits	92
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

GOGA2_HUMAN
NC score	0.062538 (rank : 58)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	124	Target Neighborhood Hits	856	Shared Neighborhood Hits	77
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

PCNT_MOUSE
NC score	0.061990 (rank : 59)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	124	Target Neighborhood Hits	1207	Shared Neighborhood Hits	86
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

REST_MOUSE
NC score	0.061006 (rank : 60)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	124	Target Neighborhood Hits	1506	Shared Neighborhood Hits	84
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

CCD27_MOUSE
NC score	0.060993 (rank : 61)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	124	Target Neighborhood Hits	461	Shared Neighborhood Hits	57
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

HMMR_MOUSE
NC score	0.060867 (rank : 62)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	124	Target Neighborhood Hits	1178	Shared Neighborhood Hits	89
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

GOGA1_MOUSE
NC score	0.060591 (rank : 63)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	124	Target Neighborhood Hits	994	Shared Neighborhood Hits	84
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

RABE2_MOUSE
NC score	0.060567 (rank : 64)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	124	Target Neighborhood Hits	598	Shared Neighborhood Hits	79
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

CCD19_HUMAN
NC score	0.059781 (rank : 65)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	124	Target Neighborhood Hits	639	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

NIN_HUMAN
NC score	0.058665 (rank : 66)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	124	Target Neighborhood Hits	1416	Shared Neighborhood Hits	86
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

AKAP9_HUMAN
NC score	0.058515 (rank : 67)	θ value	6.88961 (rank : 110)
Query Neighborhood Hits	124	Target Neighborhood Hits	1710	Shared Neighborhood Hits	97
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

INCE_HUMAN
NC score	0.058428 (rank : 68)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	124	Target Neighborhood Hits	978	Shared Neighborhood Hits	74
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

SWP70_MOUSE
NC score	0.057882 (rank : 69)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	124	Target Neighborhood Hits	1097	Shared Neighborhood Hits	80
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

CROCC_MOUSE
NC score	0.057534 (rank : 70)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	124	Target Neighborhood Hits	1460	Shared Neighborhood Hits	83
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

TUFT1_HUMAN
NC score	0.057418 (rank : 71)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	124	Target Neighborhood Hits	686	Shared Neighborhood Hits	73
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

P85A_HUMAN
NC score	0.057320 (rank : 72)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	124	Target Neighborhood Hits	479	Shared Neighborhood Hits	62
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

RAD50_HUMAN
NC score	0.057208 (rank : 73)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	124	Target Neighborhood Hits	1317	Shared Neighborhood Hits	85
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RIMB1_HUMAN
NC score	0.057034 (rank : 74)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	124	Target Neighborhood Hits	1479	Shared Neighborhood Hits	77
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

CENPE_HUMAN
NC score	0.056923 (rank : 75)	θ value	0.163984 (rank : 29)
Query Neighborhood Hits	124	Target Neighborhood Hits	2060	Shared Neighborhood Hits	99
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

RPGR1_HUMAN
NC score	0.056662 (rank : 76)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	124	Target Neighborhood Hits	578	Shared Neighborhood Hits	67
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

BPAEA_MOUSE
NC score	0.056584 (rank : 77)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	124	Target Neighborhood Hits	1480	Shared Neighborhood Hits	90
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CROCC_HUMAN
NC score	0.056374 (rank : 78)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	124	Target Neighborhood Hits	1409	Shared Neighborhood Hits	84
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

RBP24_HUMAN
NC score	0.056353 (rank : 79)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	124	Target Neighborhood Hits	1559	Shared Neighborhood Hits	92
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

CCD39_MOUSE
NC score	0.056253 (rank : 80)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	124	Target Neighborhood Hits	1026	Shared Neighborhood Hits	83
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

NAF1_MOUSE
NC score	0.056203 (rank : 81)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	124	Target Neighborhood Hits	852	Shared Neighborhood Hits	83
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

GOGA5_MOUSE
NC score	0.056023 (rank : 82)	θ value	0.365318 (rank : 34)
Query Neighborhood Hits	124	Target Neighborhood Hits	1434	Shared Neighborhood Hits	84
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

GCC2_HUMAN
NC score	0.056010 (rank : 83)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	124	Target Neighborhood Hits	1558	Shared Neighborhood Hits	91
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

INVO_HUMAN
NC score	0.055883 (rank : 84)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	124	Target Neighborhood Hits	636	Shared Neighborhood Hits	65
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

GRAP1_MOUSE
NC score	0.055870 (rank : 85)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	124	Target Neighborhood Hits	1234	Shared Neighborhood Hits	87
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

EEA1_MOUSE
NC score	0.055867 (rank : 86)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	124	Target Neighborhood Hits	1637	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

CING_MOUSE
NC score	0.055839 (rank : 87)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	124	Target Neighborhood Hits	1432	Shared Neighborhood Hits	92
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

NAF1_HUMAN
NC score	0.055770 (rank : 88)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	124	Target Neighborhood Hits	937	Shared Neighborhood Hits	83
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

CE290_HUMAN
NC score	0.055761 (rank : 89)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	124	Target Neighborhood Hits	1553	Shared Neighborhood Hits	91
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CCHCR_HUMAN
NC score	0.055675 (rank : 90)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	124	Target Neighborhood Hits	717	Shared Neighborhood Hits	79
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

P85A_MOUSE
NC score	0.055557 (rank : 91)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	124	Target Neighborhood Hits	435	Shared Neighborhood Hits	54
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

NEMO_MOUSE
NC score	0.055551 (rank : 92)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	124	Target Neighborhood Hits	658	Shared Neighborhood Hits	71
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

NIN_MOUSE
NC score	0.055435 (rank : 93)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	124	Target Neighborhood Hits	1376	Shared Neighborhood Hits	84
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

CCD21_MOUSE
NC score	0.055407 (rank : 94)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	124	Target Neighborhood Hits	1135	Shared Neighborhood Hits	79
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

RABE1_MOUSE
NC score	0.055081 (rank : 95)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	124	Target Neighborhood Hits	1105	Shared Neighborhood Hits	84
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

BRE1B_MOUSE
NC score	0.054926 (rank : 96)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	124	Target Neighborhood Hits	970	Shared Neighborhood Hits	76
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

MACF1_HUMAN
NC score	0.054772 (rank : 97)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	124	Target Neighborhood Hits	1341	Shared Neighborhood Hits	89
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

XE7_HUMAN
NC score	0.054701 (rank : 98)	θ value	1.38821 (rank : 61)
Query Neighborhood Hits	124	Target Neighborhood Hits	738	Shared Neighborhood Hits	71
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

RABE1_HUMAN
NC score	0.054570 (rank : 99)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	124	Target Neighborhood Hits	1104	Shared Neighborhood Hits	85
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RAD50_MOUSE
NC score	0.054537 (rank : 100)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	124	Target Neighborhood Hits	1366	Shared Neighborhood Hits	91
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

CR034_HUMAN
NC score	0.054406 (rank : 101)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	124	Target Neighborhood Hits	538	Shared Neighborhood Hits	66
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

FYCO1_HUMAN
NC score	0.053965 (rank : 102)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	124	Target Neighborhood Hits	1149	Shared Neighborhood Hits	84
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

PLEC1_HUMAN
NC score	0.053571 (rank : 103)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	124	Target Neighborhood Hits	1326	Shared Neighborhood Hits	90
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

KTN1_MOUSE
NC score	0.053506 (rank : 104)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	124	Target Neighborhood Hits	1324	Shared Neighborhood Hits	83
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

GRAP1_HUMAN
NC score	0.053452 (rank : 105)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	124	Target Neighborhood Hits	944	Shared Neighborhood Hits	80
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

GOGA6_HUMAN
NC score	0.053436 (rank : 106)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	124	Target Neighborhood Hits	1007	Shared Neighborhood Hits	81
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

EVPL_MOUSE
NC score	0.053031 (rank : 107)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	124	Target Neighborhood Hits	952	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

PCQAP_MOUSE
NC score	0.052990 (rank : 108)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	124	Target Neighborhood Hits	506	Shared Neighborhood Hits	44
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

CCD46_HUMAN
NC score	0.052843 (rank : 109)	θ value	8.99809 (rank : 117)
Query Neighborhood Hits	124	Target Neighborhood Hits	1430	Shared Neighborhood Hits	92
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

AZI1_MOUSE
NC score	0.052822 (rank : 110)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	124	Target Neighborhood Hits	990	Shared Neighborhood Hits	80
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

CCD91_HUMAN
NC score	0.052778 (rank : 111)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	124	Target Neighborhood Hits	868	Shared Neighborhood Hits	73
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CASP_HUMAN
NC score	0.052548 (rank : 112)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	124	Target Neighborhood Hits	1131	Shared Neighborhood Hits	78
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CCD11_MOUSE
NC score	0.052454 (rank : 113)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	124	Target Neighborhood Hits	498	Shared Neighborhood Hits	61
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

REST_HUMAN
NC score	0.052382 (rank : 114)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	124	Target Neighborhood Hits	1605	Shared Neighborhood Hits	84
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

FYCO1_MOUSE
NC score	0.052272 (rank : 115)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	124	Target Neighborhood Hits	1059	Shared Neighborhood Hits	88
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

CNTRB_MOUSE
NC score	0.052243 (rank : 116)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	124	Target Neighborhood Hits	1029	Shared Neighborhood Hits	80
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

GCC2_MOUSE
NC score	0.052093 (rank : 117)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	124	Target Neighborhood Hits	1619	Shared Neighborhood Hits	92
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GOGA3_MOUSE
NC score	0.052023 (rank : 118)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	124	Target Neighborhood Hits	1437	Shared Neighborhood Hits	85
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

GOGA5_HUMAN
NC score	0.051956 (rank : 119)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	124	Target Neighborhood Hits	1168	Shared Neighborhood Hits	83
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

SAS6_MOUSE
NC score	0.051938 (rank : 120)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	124	Target Neighborhood Hits	931	Shared Neighborhood Hits	84
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

CJ118_MOUSE
NC score	0.051753 (rank : 121)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	124	Target Neighborhood Hits	1132	Shared Neighborhood Hits	79
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

ANR26_HUMAN
NC score	0.051373 (rank : 122)	θ value	5.27518 (rank : 97)
Query Neighborhood Hits	124	Target Neighborhood Hits	1614	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CING_HUMAN
NC score	0.051367 (rank : 123)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	124	Target Neighborhood Hits	1275	Shared Neighborhood Hits	85
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CEP63_HUMAN
NC score	0.051337 (rank : 124)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	124	Target Neighborhood Hits	1005	Shared Neighborhood Hits	82
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

DESP_HUMAN
NC score	0.051021 (rank : 125)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	124	Target Neighborhood Hits	1470	Shared Neighborhood Hits	88
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

SYNE1_HUMAN
NC score	0.050968 (rank : 126)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	124	Target Neighborhood Hits	1484	Shared Neighborhood Hits	87
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

CK5P2_MOUSE
NC score	0.050943 (rank : 127)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	124	Target Neighborhood Hits	1151	Shared Neighborhood Hits	84
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

GOGA3_HUMAN
NC score	0.050902 (rank : 128)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	124	Target Neighborhood Hits	1317	Shared Neighborhood Hits	84
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

CCHCR_MOUSE
NC score	0.050859 (rank : 129)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	124	Target Neighborhood Hits	932	Shared Neighborhood Hits	77
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CKAP4_MOUSE
NC score	0.050747 (rank : 130)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	124	Target Neighborhood Hits	596	Shared Neighborhood Hits	74
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

AZI1_HUMAN
NC score	0.050536 (rank : 131)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	124	Target Neighborhood Hits	1000	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

HOOK1_HUMAN
NC score	0.050491 (rank : 132)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	124	Target Neighborhood Hits	942	Shared Neighborhood Hits	80
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

CCD39_HUMAN
NC score	0.050462 (rank : 133)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	124	Target Neighborhood Hits	868	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

LRC45_HUMAN
NC score	0.050442 (rank : 134)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	124	Target Neighborhood Hits	933	Shared Neighborhood Hits	83
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

PININ_HUMAN
NC score	0.050417 (rank : 135)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	124	Target Neighborhood Hits	753	Shared Neighborhood Hits	65
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

CCD13_HUMAN
NC score	0.050342 (rank : 136)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	124	Target Neighborhood Hits	721	Shared Neighborhood Hits	71
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

PEPL_HUMAN
NC score	0.050323 (rank : 137)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	124	Target Neighborhood Hits	1141	Shared Neighborhood Hits	78
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

CASP_MOUSE
NC score	0.050295 (rank : 138)	θ value	5.27518 (rank : 98)
Query Neighborhood Hits	124	Target Neighborhood Hits	1152	Shared Neighborhood Hits	77
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

TMF1_HUMAN
NC score	0.050231 (rank : 139)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	124	Target Neighborhood Hits	987	Shared Neighborhood Hits	74
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

CE152_HUMAN
NC score	0.050146 (rank : 140)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	124	Target Neighborhood Hits	976	Shared Neighborhood Hits	78
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

C102B_HUMAN
NC score	0.050053 (rank : 141)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	124	Target Neighborhood Hits	542	Shared Neighborhood Hits	65
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

CEP55_HUMAN
NC score	0.050019 (rank : 142)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	124	Target Neighborhood Hits	504	Shared Neighborhood Hits	66
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

MY18A_HUMAN
NC score	0.049082 (rank : 143)	θ value	1.06291 (rank : 55)
Query Neighborhood Hits	124	Target Neighborhood Hits	1929	Shared Neighborhood Hits	95
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

APOE_MOUSE
NC score	0.048739 (rank : 144)	θ value	8.99809 (rank : 116)
Query Neighborhood Hits	124	Target Neighborhood Hits	319	Shared Neighborhood Hits	51
SwissProt Accessions	P08226	Gene names	Apoe
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

HAPIP_HUMAN
NC score	0.048531 (rank : 145)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	124	Target Neighborhood Hits	350	Shared Neighborhood Hits	48
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

ANR26_MOUSE
NC score	0.048491 (rank : 146)	θ value	6.88961 (rank : 111)
Query Neighborhood Hits	124	Target Neighborhood Hits	1554	Shared Neighborhood Hits	91
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

MLL2_HUMAN
NC score	0.048200 (rank : 147)	θ value	1.06291 (rank : 54)
Query Neighborhood Hits	124	Target Neighborhood Hits	1788	Shared Neighborhood Hits	66
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MY18A_MOUSE
NC score	0.047074 (rank : 148)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	124	Target Neighborhood Hits	1989	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

RUFY2_HUMAN
NC score	0.046857 (rank : 149)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	124	Target Neighborhood Hits	1208	Shared Neighborhood Hits	86
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

APOA4_MOUSE
NC score	0.046631 (rank : 150)	θ value	6.88961 (rank : 112)
Query Neighborhood Hits	124	Target Neighborhood Hits	435	Shared Neighborhood Hits	51
SwissProt Accessions	P06728	Gene names	Apoa4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

CUTL1_HUMAN
NC score	0.046592 (rank : 151)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	124	Target Neighborhood Hits	1574	Shared Neighborhood Hits	81
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

CUTL1_MOUSE
NC score	0.046384 (rank : 152)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	124	Target Neighborhood Hits	1620	Shared Neighborhood Hits	83
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

DIDO1_HUMAN
NC score	0.046229 (rank : 153)	θ value	0.0961366 (rank : 26)
Query Neighborhood Hits	124	Target Neighborhood Hits	960	Shared Neighborhood Hits	25
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

MED12_HUMAN
NC score	0.044625 (rank : 154)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	124	Target Neighborhood Hits	262	Shared Neighborhood Hits	37
SwissProt Accessions	Q93074, O15410, O75557, Q9UHV6, Q9UND7	Gene names	MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 12 (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (OPA-containing protein) (Trinucleotide repeat-containing gene 11 protein).

LRSM1_HUMAN
NC score	0.043719 (rank : 155)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	124	Target Neighborhood Hits	1078	Shared Neighborhood Hits	79
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

SPTA1_HUMAN
NC score	0.041668 (rank : 156)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	124	Target Neighborhood Hits	748	Shared Neighborhood Hits	74
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

K1683_HUMAN
NC score	0.040950 (rank : 157)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	124	Target Neighborhood Hits	240	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

CTRO_MOUSE
NC score	0.040255 (rank : 158)	θ value	0.21417 (rank : 30)
Query Neighborhood Hits	124	Target Neighborhood Hits	2344	Shared Neighborhood Hits	89
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

MYH6_HUMAN
NC score	0.039803 (rank : 159)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	124	Target Neighborhood Hits	1426	Shared Neighborhood Hits	80
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

CTRO_HUMAN
NC score	0.039312 (rank : 160)	θ value	0.0563607 (rank : 23)
Query Neighborhood Hits	124	Target Neighborhood Hits	2092	Shared Neighborhood Hits	90
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

MYH7_HUMAN
NC score	0.039128 (rank : 161)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	124	Target Neighborhood Hits	1559	Shared Neighborhood Hits	84
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

SOCS4_MOUSE
NC score	0.039022 (rank : 162)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	124	Target Neighborhood Hits	69	Shared Neighborhood Hits	19
SwissProt Accessions	Q91ZA6	Gene names	Socs4, Socs7
Domain Architecture
Description	Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7).

FOXP2_MOUSE
NC score	0.037654 (rank : 163)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	124	Target Neighborhood Hits	366	Shared Neighborhood Hits	44
SwissProt Accessions	P58463, Q6PD37, Q8C4F0, Q8R441	Gene names	Foxp2
Domain Architecture
Description	Forkhead box protein P2.

FOXP2_HUMAN
NC score	0.036832 (rank : 164)	θ value	0.813845 (rank : 45)
Query Neighborhood Hits	124	Target Neighborhood Hits	366	Shared Neighborhood Hits	45
SwissProt Accessions	O15409, Q6ZND1, Q75MJ3, Q8IZE0, Q8N0W2, Q8N6B7, Q8N6B8, Q8NFQ1, Q8NFQ2, Q8NFQ3, Q8NFQ4, Q8TD74	Gene names	FOXP2, CAGH44, TNRC10
Domain Architecture
Description	Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat- containing gene 10 protein).

KIF4A_MOUSE
NC score	0.036727 (rank : 165)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	124	Target Neighborhood Hits	1033	Shared Neighborhood Hits	80
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

SOCS4_HUMAN
NC score	0.036679 (rank : 166)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	124	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXH5	Gene names	SOCS4, SOCS7
Domain Architecture
Description	Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7).

RAI14_HUMAN
NC score	0.034247 (rank : 167)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	124	Target Neighborhood Hits	1367	Shared Neighborhood Hits	75
SwissProt Accessions	Q9P0K7, Q6V1W9, Q7Z5I4, Q7Z733, Q9P2L2, Q9Y3T5	Gene names	RAI14, KIAA1334, NORPEG
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein).

MRCKB_HUMAN
NC score	0.029496 (rank : 168)	θ value	0.813845 (rank : 49)
Query Neighborhood Hits	124	Target Neighborhood Hits	2239	Shared Neighborhood Hits	97
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

EVC_MOUSE
NC score	0.026213 (rank : 169)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	124	Target Neighborhood Hits	80	Shared Neighborhood Hits	17
SwissProt Accessions	P57680	Gene names	Evc
Domain Architecture	No domain graphic available
Description	Ellis-van Creveld syndrome protein homolog.

SOCS5_MOUSE
NC score	0.026034 (rank : 170)	θ value	8.99809 (rank : 123)
Query Neighborhood Hits	124	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	O54928	Gene names	Socs5, Cish5
Domain Architecture
Description	Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5).

SOCS5_HUMAN
NC score	0.025754 (rank : 171)	θ value	8.99809 (rank : 122)
Query Neighborhood Hits	124	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	O75159, Q8IYZ4	Gene names	SOCS5, CIS6, CISH5, CISH6, KIAA0671
Domain Architecture
Description	Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5) (Cytokine-inducible SH2 protein 6) (CIS-6).

MRCKG_HUMAN
NC score	0.024351 (rank : 172)	θ value	0.813845 (rank : 50)
Query Neighborhood Hits	124	Target Neighborhood Hits	1519	Shared Neighborhood Hits	82
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

CHIN_HUMAN
NC score	0.023127 (rank : 173)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	124	Target Neighborhood Hits	227	Shared Neighborhood Hits	18
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

K1C10_HUMAN
NC score	0.022867 (rank : 174)	θ value	0.813845 (rank : 48)
Query Neighborhood Hits	124	Target Neighborhood Hits	526	Shared Neighborhood Hits	64
SwissProt Accessions	P13645, Q14664, Q8N175	Gene names	KRT10
Domain Architecture
Description	Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10).

PPT2_HUMAN
NC score	0.021633 (rank : 175)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	124	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UMR5, O14799, Q0P6K0, Q5JP13, Q5JP14, Q5JQF0, Q5SSX4, Q5SSX5, Q5SSX6, Q5STJ4, Q5STJ5, Q5STJ6, Q6FI80, Q99945	Gene names	PPT2
Domain Architecture
Description	Lysosomal thioesterase PPT2 precursor (EC 3.1.2.-) (PPT-2) (S- thioesterase G14).

BAZ1B_MOUSE
NC score	0.020752 (rank : 176)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	124	Target Neighborhood Hits	394	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

CHIN_MOUSE
NC score	0.020533 (rank : 177)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	124	Target Neighborhood Hits	229	Shared Neighborhood Hits	17
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

K22E_HUMAN
NC score	0.020481 (rank : 178)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	124	Target Neighborhood Hits	515	Shared Neighborhood Hits	58
SwissProt Accessions	P35908	Gene names	KRT2A, KRT2E
Domain Architecture
Description	Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (K2e) (CK 2e).

SLK_HUMAN
NC score	0.018118 (rank : 179)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	124	Target Neighborhood Hits	1775	Shared Neighborhood Hits	82
SwissProt Accessions	Q9H2G2, O00211, Q6P1Z4, Q86WU7, Q86WW1, Q92603, Q9NQL0, Q9NQL1	Gene names	SLK, KIAA0204, STK2
Domain Architecture	No domain graphic available
Description	STE20-like serine/threonine-protein kinase (EC 2.7.11.1) (STE20-like kinase) (STE20-related serine/threonine-protein kinase) (STE20-related kinase) (hSLK) (Serine/threonine-protein kinase 2) (CTCL tumor antigen se20-9).

BAIP2_HUMAN
NC score	0.017985 (rank : 180)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	124	Target Neighborhood Hits	192	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UQB8, O43858, Q53HB1, Q86WC1, Q8N5C0, Q96CR7, Q9UBR3, Q9UQ43	Gene names	BAIAP2
Domain Architecture	No domain graphic available
Description	Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI1- associated protein 2) (BAI-associated protein 2) (Protein BAP2) (Insulin receptor substrate p53) (IRSp53) (Insulin receptor substrate protein of 53 kDa) (Insulin receptor substrate p53/p58) (IRSp53/58) (IRS-58) (Fas ligand-associated factor 3) (FLAF3).

DNMBP_HUMAN
NC score	0.017247 (rank : 181)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	124	Target Neighborhood Hits	413	Shared Neighborhood Hits	25
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

M4K4_HUMAN
NC score	0.016016 (rank : 182)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	124	Target Neighborhood Hits	1589	Shared Neighborhood Hits	73
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

BIN1_HUMAN
NC score	0.014954 (rank : 183)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	124	Target Neighborhood Hits	335	Shared Neighborhood Hits	19
SwissProt Accessions	O00499, O00297, O00545, O43867, O60552, O60553, O60554, O60555, O75514, O75515, O75516, O75517, O75518, Q92944, Q99688	Gene names	BIN1, AMPHL
Domain Architecture
Description	Myc box-dependent-interacting protein 1 (Bridging integrator 1) (Amphiphysin-like protein) (Amphiphysin II) (Box-dependent myc- interacting protein 1).

UCHL5_HUMAN
NC score	0.010599 (rank : 184)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	124	Target Neighborhood Hits	35	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y5K5, Q5LJA6, Q5LJA7, Q8TBS4, Q96BJ9, Q9H1W5, Q9P0I3, Q9UQN2	Gene names	UCHL5, UCH37
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase isozyme L5 (EC 3.4.19.12) (UCH- L5) (Ubiquitin thioesterase L5) (Ubiquitin C-terminal hydrolase UCH37).

MLL3_HUMAN
NC score	0.010521 (rank : 185)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	124	Target Neighborhood Hits	1644	Shared Neighborhood Hits	41
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

PAR14_MOUSE
NC score	0.008090 (rank : 186)	θ value	8.99809 (rank : 120)
Query Neighborhood Hits	124	Target Neighborhood Hits	113	Shared Neighborhood Hits	13
SwissProt Accessions	Q2EMV9, Q571C6, Q8BN35, Q8VDT6	Gene names	Parp14, Kiaa1268
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 14 (EC 2.4.2.30) (PARP-14) (Collaborator of STAT6) (CoaSt6).

WNK2_HUMAN
NC score	0.003403 (rank : 187)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	124	Target Neighborhood Hits	1407	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

PGBM_HUMAN
NC score	0.001968 (rank : 188)	θ value	0.47712 (rank : 40)
Query Neighborhood Hits	124	Target Neighborhood Hits	1113	Shared Neighborhood Hits	3
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

SRMS_HUMAN
NC score	0.001748 (rank : 189)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	124	Target Neighborhood Hits	946	Shared Neighborhood Hits	21
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).