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Network neighborhood for query Sequence : STA5A_HUMAN

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STA5A_HUMAN
SwissProt Accessions	P42229	Gene names	STAT5A, STAT5
Domain Architecture
Description	Signal transducer and activator of transcription 5A.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

STA5A_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	140	Target Neighborhood Hits	140	Shared Neighborhood Hits	140
SwissProt Accessions	P42229	Gene names	STAT5A, STAT5
Domain Architecture
Description	Signal transducer and activator of transcription 5A.

STA5A_MOUSE
θ value	0 (rank : 2)	NC score	0.995448 (rank : 2)
Query Neighborhood Hits	140	Target Neighborhood Hits	128	Shared Neighborhood Hits	102
SwissProt Accessions	P42230	Gene names	Stat5a, Mgf, Mpf
Domain Architecture
Description	Signal transducer and activator of transcription 5A (Mammary gland factor).

STA5B_HUMAN
θ value	0 (rank : 3)	NC score	0.994214 (rank : 3)
Query Neighborhood Hits	140	Target Neighborhood Hits	103	Shared Neighborhood Hits	89
SwissProt Accessions	P51692, Q8WWS8	Gene names	STAT5B
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STA5B_MOUSE
θ value	0 (rank : 4)	NC score	0.993426 (rank : 4)
Query Neighborhood Hits	140	Target Neighborhood Hits	124	Shared Neighborhood Hits	95
SwissProt Accessions	P42232, Q541Q5, Q60804, Q8K3Q1, Q9JKM1	Gene names	Stat5b
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STAT6_HUMAN
θ value	3.64273e-126 (rank : 5)	NC score	0.936135 (rank : 6)
Query Neighborhood Hits	140	Target Neighborhood Hits	132	Shared Neighborhood Hits	24
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

STAT6_MOUSE
θ value	6.21357e-126 (rank : 6)	NC score	0.942533 (rank : 5)
Query Neighborhood Hits	140	Target Neighborhood Hits	78	Shared Neighborhood Hits	21
SwissProt Accessions	P52633	Gene names	Stat6
Domain Architecture
Description	Signal transducer and transcription activator 6.

STAT3_HUMAN
θ value	2.91998e-83 (rank : 7)	NC score	0.887263 (rank : 9)
Query Neighborhood Hits	140	Target Neighborhood Hits	155	Shared Neighborhood Hits	42
SwissProt Accessions	P40763, O14916, Q9BW54	Gene names	STAT3, APRF
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT3_MOUSE
θ value	2.91998e-83 (rank : 8)	NC score	0.887261 (rank : 10)
Query Neighborhood Hits	140	Target Neighborhood Hits	155	Shared Neighborhood Hits	42
SwissProt Accessions	P42227	Gene names	Stat3, Aprf
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT4_HUMAN
θ value	1.65806e-78 (rank : 9)	NC score	0.889748 (rank : 8)
Query Neighborhood Hits	140	Target Neighborhood Hits	91	Shared Neighborhood Hits	30
SwissProt Accessions	Q14765, Q96NZ6	Gene names	STAT4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STAT4_MOUSE
θ value	4.51533e-76 (rank : 10)	NC score	0.894557 (rank : 7)
Query Neighborhood Hits	140	Target Neighborhood Hits	73	Shared Neighborhood Hits	32
SwissProt Accessions	P42228	Gene names	Stat4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STAT1_HUMAN
θ value	1.45253e-74 (rank : 11)	NC score	0.883141 (rank : 11)
Query Neighborhood Hits	140	Target Neighborhood Hits	128	Shared Neighborhood Hits	50
SwissProt Accessions	P42224	Gene names	STAT1
Domain Architecture
Description	Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84).

STAT1_MOUSE
θ value	6.10265e-73 (rank : 12)	NC score	0.879778 (rank : 12)
Query Neighborhood Hits	140	Target Neighborhood Hits	151	Shared Neighborhood Hits	49
SwissProt Accessions	P42225	Gene names	Stat1
Domain Architecture
Description	Signal transducer and activator of transcription 1.

STAT2_HUMAN
θ value	3.1488e-53 (rank : 13)	NC score	0.867706 (rank : 13)
Query Neighborhood Hits	140	Target Neighborhood Hits	99	Shared Neighborhood Hits	31
SwissProt Accessions	P52630, Q16430, Q16431	Gene names	STAT2
Domain Architecture
Description	Signal transducer and activator of transcription 2 (p113).

STAT2_MOUSE
θ value	2.18568e-46 (rank : 14)	NC score	0.813506 (rank : 14)
Query Neighborhood Hits	140	Target Neighborhood Hits	175	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

GOGB1_HUMAN
θ value	1.43324e-05 (rank : 15)	NC score	0.104871 (rank : 16)
Query Neighborhood Hits	140	Target Neighborhood Hits	2297	Shared Neighborhood Hits	115
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CI093_HUMAN
θ value	0.00228821 (rank : 16)	NC score	0.100539 (rank : 17)
Query Neighborhood Hits	140	Target Neighborhood Hits	1088	Shared Neighborhood Hits	99
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CP135_HUMAN
θ value	0.00390308 (rank : 17)	NC score	0.090865 (rank : 21)
Query Neighborhood Hits	140	Target Neighborhood Hits	1290	Shared Neighborhood Hits	102
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

REST_MOUSE
θ value	0.00509761 (rank : 18)	NC score	0.077063 (rank : 40)
Query Neighborhood Hits	140	Target Neighborhood Hits	1506	Shared Neighborhood Hits	100
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

RIMB1_MOUSE
θ value	0.0193708 (rank : 19)	NC score	0.093401 (rank : 19)
Query Neighborhood Hits	140	Target Neighborhood Hits	1376	Shared Neighborhood Hits	98
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

CTRO_HUMAN
θ value	0.0563607 (rank : 20)	NC score	0.045757 (rank : 277)
Query Neighborhood Hits	140	Target Neighborhood Hits	2092	Shared Neighborhood Hits	108
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

GOGA2_MOUSE
θ value	0.0563607 (rank : 21)	NC score	0.093705 (rank : 18)
Query Neighborhood Hits	140	Target Neighborhood Hits	944	Shared Neighborhood Hits	103
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

REST_HUMAN
θ value	0.0563607 (rank : 22)	NC score	0.067970 (rank : 68)
Query Neighborhood Hits	140	Target Neighborhood Hits	1605	Shared Neighborhood Hits	100
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

KCT2_MOUSE
θ value	0.0736092 (rank : 23)	NC score	0.052637 (rank : 224)
Query Neighborhood Hits	140	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K201, Q5SVC5, Q922L7, Q9CVN1	Gene names	Kct2
Domain Architecture	No domain graphic available
Description	Keratinocytes-associated transmembrane protein 2 precursor.

BRE1A_HUMAN
θ value	0.0961366 (rank : 24)	NC score	0.078243 (rank : 35)
Query Neighborhood Hits	140	Target Neighborhood Hits	1071	Shared Neighborhood Hits	91
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

BSN_MOUSE
θ value	0.0961366 (rank : 25)	NC score	0.042890 (rank : 279)
Query Neighborhood Hits	140	Target Neighborhood Hits	2057	Shared Neighborhood Hits	72
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CENPF_HUMAN
θ value	0.0961366 (rank : 26)	NC score	0.084495 (rank : 28)
Query Neighborhood Hits	140	Target Neighborhood Hits	1932	Shared Neighborhood Hits	113
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

GOGA4_MOUSE
θ value	0.0961366 (rank : 27)	NC score	0.087242 (rank : 25)
Query Neighborhood Hits	140	Target Neighborhood Hits	1939	Shared Neighborhood Hits	114
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

PCNT_HUMAN
θ value	0.0961366 (rank : 28)	NC score	0.093044 (rank : 20)
Query Neighborhood Hits	140	Target Neighborhood Hits	1551	Shared Neighborhood Hits	106
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

TRIPB_HUMAN
θ value	0.0961366 (rank : 29)	NC score	0.089662 (rank : 23)
Query Neighborhood Hits	140	Target Neighborhood Hits	1587	Shared Neighborhood Hits	108
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CP250_HUMAN
θ value	0.125558 (rank : 30)	NC score	0.087790 (rank : 24)
Query Neighborhood Hits	140	Target Neighborhood Hits	1805	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

HIP1_HUMAN
θ value	0.125558 (rank : 31)	NC score	0.078188 (rank : 36)
Query Neighborhood Hits	140	Target Neighborhood Hits	1016	Shared Neighborhood Hits	92
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

NEMO_MOUSE
θ value	0.125558 (rank : 32)	NC score	0.070955 (rank : 54)
Query Neighborhood Hits	140	Target Neighborhood Hits	658	Shared Neighborhood Hits	92
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

BSN_HUMAN
θ value	0.163984 (rank : 33)	NC score	0.050307 (rank : 265)
Query Neighborhood Hits	140	Target Neighborhood Hits	1537	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

DIDO1_HUMAN
θ value	0.163984 (rank : 34)	NC score	0.046660 (rank : 271)
Query Neighborhood Hits	140	Target Neighborhood Hits	960	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

PCQAP_MOUSE
θ value	0.163984 (rank : 35)	NC score	0.063682 (rank : 92)
Query Neighborhood Hits	140	Target Neighborhood Hits	506	Shared Neighborhood Hits	53
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

CCD21_HUMAN
θ value	0.21417 (rank : 36)	NC score	0.082155 (rank : 31)
Query Neighborhood Hits	140	Target Neighborhood Hits	1228	Shared Neighborhood Hits	101
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CF060_HUMAN
θ value	0.21417 (rank : 37)	NC score	0.085911 (rank : 26)
Query Neighborhood Hits	140	Target Neighborhood Hits	1270	Shared Neighborhood Hits	99
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CING_MOUSE
θ value	0.21417 (rank : 38)	NC score	0.068630 (rank : 65)
Query Neighborhood Hits	140	Target Neighborhood Hits	1432	Shared Neighborhood Hits	105
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CP250_MOUSE
θ value	0.21417 (rank : 39)	NC score	0.077681 (rank : 38)
Query Neighborhood Hits	140	Target Neighborhood Hits	1583	Shared Neighborhood Hits	107
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CTRO_MOUSE
θ value	0.21417 (rank : 40)	NC score	0.046377 (rank : 272)
Query Neighborhood Hits	140	Target Neighborhood Hits	2344	Shared Neighborhood Hits	110
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

GOGA1_HUMAN
θ value	0.279714 (rank : 41)	NC score	0.074582 (rank : 46)
Query Neighborhood Hits	140	Target Neighborhood Hits	1222	Shared Neighborhood Hits	102
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

SH22A_HUMAN
θ value	0.279714 (rank : 42)	NC score	0.114780 (rank : 15)
Query Neighborhood Hits	140	Target Neighborhood Hits	144	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

TFAP4_HUMAN
θ value	0.279714 (rank : 43)	NC score	0.090048 (rank : 22)
Query Neighborhood Hits	140	Target Neighborhood Hits	289	Shared Neighborhood Hits	58
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

BPAEA_MOUSE
θ value	0.365318 (rank : 44)	NC score	0.066527 (rank : 74)
Query Neighborhood Hits	140	Target Neighborhood Hits	1480	Shared Neighborhood Hits	106
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CCD45_MOUSE
θ value	0.365318 (rank : 45)	NC score	0.075367 (rank : 42)
Query Neighborhood Hits	140	Target Neighborhood Hits	663	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

ERBB3_MOUSE
θ value	0.365318 (rank : 46)	NC score	0.005183 (rank : 307)
Query Neighborhood Hits	140	Target Neighborhood Hits	898	Shared Neighborhood Hits	13
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

PLEC1_HUMAN
θ value	0.365318 (rank : 47)	NC score	0.061951 (rank : 107)
Query Neighborhood Hits	140	Target Neighborhood Hits	1326	Shared Neighborhood Hits	100
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

ANR26_MOUSE
θ value	0.47712 (rank : 48)	NC score	0.058563 (rank : 134)
Query Neighborhood Hits	140	Target Neighborhood Hits	1554	Shared Neighborhood Hits	106
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

GOGA4_HUMAN
θ value	0.47712 (rank : 49)	NC score	0.077193 (rank : 39)
Query Neighborhood Hits	140	Target Neighborhood Hits	2034	Shared Neighborhood Hits	114
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

HAPIP_HUMAN
θ value	0.47712 (rank : 50)	NC score	0.050726 (rank : 257)
Query Neighborhood Hits	140	Target Neighborhood Hits	350	Shared Neighborhood Hits	53
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

HSH2D_HUMAN
θ value	0.47712 (rank : 51)	NC score	0.070834 (rank : 56)
Query Neighborhood Hits	140	Target Neighborhood Hits	159	Shared Neighborhood Hits	22
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

P55G_HUMAN
θ value	0.47712 (rank : 52)	NC score	0.079519 (rank : 34)
Query Neighborhood Hits	140	Target Neighborhood Hits	451	Shared Neighborhood Hits	74
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	0.47712 (rank : 53)	NC score	0.083086 (rank : 30)
Query Neighborhood Hits	140	Target Neighborhood Hits	401	Shared Neighborhood Hits	72
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

RBP24_HUMAN
θ value	0.62314 (rank : 54)	NC score	0.069878 (rank : 60)
Query Neighborhood Hits	140	Target Neighborhood Hits	1559	Shared Neighborhood Hits	107
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

CNTRB_HUMAN
θ value	0.813845 (rank : 55)	NC score	0.077916 (rank : 37)
Query Neighborhood Hits	140	Target Neighborhood Hits	690	Shared Neighborhood Hits	94
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

GCC2_HUMAN
θ value	0.813845 (rank : 56)	NC score	0.069487 (rank : 62)
Query Neighborhood Hits	140	Target Neighborhood Hits	1558	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

K1683_HUMAN
θ value	0.813845 (rank : 57)	NC score	0.048275 (rank : 268)
Query Neighborhood Hits	140	Target Neighborhood Hits	240	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

MRCKG_HUMAN
θ value	0.813845 (rank : 58)	NC score	0.028461 (rank : 294)
Query Neighborhood Hits	140	Target Neighborhood Hits	1519	Shared Neighborhood Hits	96
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

MRCKG_MOUSE
θ value	0.813845 (rank : 59)	NC score	0.023156 (rank : 298)
Query Neighborhood Hits	140	Target Neighborhood Hits	1466	Shared Neighborhood Hits	93
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

RUFY1_HUMAN
θ value	0.813845 (rank : 60)	NC score	0.056042 (rank : 168)
Query Neighborhood Hits	140	Target Neighborhood Hits	848	Shared Neighborhood Hits	94
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

CCD11_HUMAN
θ value	1.06291 (rank : 61)	NC score	0.084682 (rank : 27)
Query Neighborhood Hits	140	Target Neighborhood Hits	822	Shared Neighborhood Hits	96
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

KIF5A_HUMAN
θ value	1.06291 (rank : 62)	NC score	0.041660 (rank : 280)
Query Neighborhood Hits	140	Target Neighborhood Hits	843	Shared Neighborhood Hits	86
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

KIF5A_MOUSE
θ value	1.06291 (rank : 63)	NC score	0.041334 (rank : 281)
Query Neighborhood Hits	140	Target Neighborhood Hits	859	Shared Neighborhood Hits	83
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

NUMA1_HUMAN
θ value	1.06291 (rank : 64)	NC score	0.076711 (rank : 41)
Query Neighborhood Hits	140	Target Neighborhood Hits	1523	Shared Neighborhood Hits	105
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

ANR26_HUMAN
θ value	1.38821 (rank : 65)	NC score	0.061437 (rank : 113)
Query Neighborhood Hits	140	Target Neighborhood Hits	1614	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CP135_MOUSE
θ value	1.38821 (rank : 66)	NC score	0.081639 (rank : 32)
Query Neighborhood Hits	140	Target Neighborhood Hits	1278	Shared Neighborhood Hits	104
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

EEA1_HUMAN
θ value	1.38821 (rank : 67)	NC score	0.073565 (rank : 50)
Query Neighborhood Hits	140	Target Neighborhood Hits	1796	Shared Neighborhood Hits	110
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

FOXP2_HUMAN
θ value	1.38821 (rank : 68)	NC score	0.037519 (rank : 286)
Query Neighborhood Hits	140	Target Neighborhood Hits	366	Shared Neighborhood Hits	57
SwissProt Accessions	O15409, Q6ZND1, Q75MJ3, Q8IZE0, Q8N0W2, Q8N6B7, Q8N6B8, Q8NFQ1, Q8NFQ2, Q8NFQ3, Q8NFQ4, Q8TD74	Gene names	FOXP2, CAGH44, TNRC10
Domain Architecture
Description	Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat- containing gene 10 protein).

FOXP2_MOUSE
θ value	1.38821 (rank : 69)	NC score	0.038714 (rank : 284)
Query Neighborhood Hits	140	Target Neighborhood Hits	366	Shared Neighborhood Hits	57
SwissProt Accessions	P58463, Q6PD37, Q8C4F0, Q8R441	Gene names	Foxp2
Domain Architecture
Description	Forkhead box protein P2.

G3BP_HUMAN
θ value	1.38821 (rank : 70)	NC score	0.033323 (rank : 291)
Query Neighborhood Hits	140	Target Neighborhood Hits	219	Shared Neighborhood Hits	10
SwissProt Accessions	Q13283	Gene names	G3BP, G3BP1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

HSH2D_MOUSE
θ value	1.38821 (rank : 71)	NC score	0.084196 (rank : 29)
Query Neighborhood Hits	140	Target Neighborhood Hits	124	Shared Neighborhood Hits	25
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

M4K4_HUMAN
θ value	1.38821 (rank : 72)	NC score	0.018583 (rank : 303)
Query Neighborhood Hits	140	Target Neighborhood Hits	1589	Shared Neighborhood Hits	85
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MRCKB_HUMAN
θ value	1.38821 (rank : 73)	NC score	0.035601 (rank : 288)
Query Neighborhood Hits	140	Target Neighborhood Hits	2239	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

P85A_HUMAN
θ value	1.38821 (rank : 74)	NC score	0.060995 (rank : 117)
Query Neighborhood Hits	140	Target Neighborhood Hits	479	Shared Neighborhood Hits	64
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
θ value	1.38821 (rank : 75)	NC score	0.059263 (rank : 129)
Query Neighborhood Hits	140	Target Neighborhood Hits	435	Shared Neighborhood Hits	57
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

SWP70_MOUSE
θ value	1.38821 (rank : 76)	NC score	0.065373 (rank : 79)
Query Neighborhood Hits	140	Target Neighborhood Hits	1097	Shared Neighborhood Hits	95
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

G3BP_MOUSE
θ value	1.81305 (rank : 77)	NC score	0.027123 (rank : 295)
Query Neighborhood Hits	140	Target Neighborhood Hits	209	Shared Neighborhood Hits	7
SwissProt Accessions	P97855	Gene names	G3bp, G3bp1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

HIP1R_MOUSE
θ value	1.81305 (rank : 78)	NC score	0.070642 (rank : 57)
Query Neighborhood Hits	140	Target Neighborhood Hits	959	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

P85B_MOUSE
θ value	1.81305 (rank : 79)	NC score	0.074856 (rank : 45)
Query Neighborhood Hits	140	Target Neighborhood Hits	519	Shared Neighborhood Hits	78
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

MY18A_HUMAN
θ value	2.36792 (rank : 80)	NC score	0.056598 (rank : 163)
Query Neighborhood Hits	140	Target Neighborhood Hits	1929	Shared Neighborhood Hits	111
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

RAD50_HUMAN
θ value	2.36792 (rank : 81)	NC score	0.067736 (rank : 72)
Query Neighborhood Hits	140	Target Neighborhood Hits	1317	Shared Neighborhood Hits	99
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

TRHY_HUMAN
θ value	2.36792 (rank : 82)	NC score	0.070951 (rank : 55)
Query Neighborhood Hits	140	Target Neighborhood Hits	1385	Shared Neighborhood Hits	95
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

TUFT1_HUMAN
θ value	2.36792 (rank : 83)	NC score	0.066392 (rank : 75)
Query Neighborhood Hits	140	Target Neighborhood Hits	686	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

CCD39_HUMAN
θ value	3.0926 (rank : 84)	NC score	0.062954 (rank : 97)
Query Neighborhood Hits	140	Target Neighborhood Hits	868	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CCD39_MOUSE
θ value	3.0926 (rank : 85)	NC score	0.067940 (rank : 69)
Query Neighborhood Hits	140	Target Neighborhood Hits	1026	Shared Neighborhood Hits	94
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

CHIN_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.022122 (rank : 299)
Query Neighborhood Hits	140	Target Neighborhood Hits	227	Shared Neighborhood Hits	19
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

ERBB3_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.003923 (rank : 309)
Query Neighborhood Hits	140	Target Neighborhood Hits	918	Shared Neighborhood Hits	13
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

MED12_HUMAN
θ value	3.0926 (rank : 88)	NC score	0.048427 (rank : 267)
Query Neighborhood Hits	140	Target Neighborhood Hits	262	Shared Neighborhood Hits	43
SwissProt Accessions	Q93074, O15410, O75557, Q9UHV6, Q9UND7	Gene names	MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 12 (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (OPA-containing protein) (Trinucleotide repeat-containing gene 11 protein).

MLL2_HUMAN
θ value	3.0926 (rank : 89)	NC score	0.047100 (rank : 269)
Query Neighborhood Hits	140	Target Neighborhood Hits	1788	Shared Neighborhood Hits	74
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYH6_HUMAN
θ value	3.0926 (rank : 90)	NC score	0.046114 (rank : 276)
Query Neighborhood Hits	140	Target Neighborhood Hits	1426	Shared Neighborhood Hits	94
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

P85B_HUMAN
θ value	3.0926 (rank : 91)	NC score	0.074912 (rank : 44)
Query Neighborhood Hits	140	Target Neighborhood Hits	543	Shared Neighborhood Hits	77
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

SPTA1_HUMAN
θ value	3.0926 (rank : 92)	NC score	0.046252 (rank : 274)
Query Neighborhood Hits	140	Target Neighborhood Hits	748	Shared Neighborhood Hits	81
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

HIP1R_HUMAN
θ value	4.03905 (rank : 93)	NC score	0.071574 (rank : 53)
Query Neighborhood Hits	140	Target Neighborhood Hits	809	Shared Neighborhood Hits	91
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

HMMR_MOUSE
θ value	4.03905 (rank : 94)	NC score	0.070059 (rank : 59)
Query Neighborhood Hits	140	Target Neighborhood Hits	1178	Shared Neighborhood Hits	103
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

INCE_HUMAN
θ value	4.03905 (rank : 95)	NC score	0.064720 (rank : 83)
Query Neighborhood Hits	140	Target Neighborhood Hits	978	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

LZTS1_HUMAN
θ value	4.03905 (rank : 96)	NC score	0.057296 (rank : 152)
Query Neighborhood Hits	140	Target Neighborhood Hits	532	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MYH7_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.045471 (rank : 278)
Query Neighborhood Hits	140	Target Neighborhood Hits	1559	Shared Neighborhood Hits	99
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

RABE2_MOUSE
θ value	4.03905 (rank : 98)	NC score	0.069552 (rank : 61)
Query Neighborhood Hits	140	Target Neighborhood Hits	598	Shared Neighborhood Hits	95
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

CD72_MOUSE
θ value	5.27518 (rank : 99)	NC score	0.037937 (rank : 285)
Query Neighborhood Hits	140	Target Neighborhood Hits	262	Shared Neighborhood Hits	48
SwissProt Accessions	P21855, Q64225	Gene names	Cd72, Ly-32, Lyb-2
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2) (Antigen Ly-32).

CHIN_MOUSE
θ value	5.27518 (rank : 100)	NC score	0.019534 (rank : 302)
Query Neighborhood Hits	140	Target Neighborhood Hits	229	Shared Neighborhood Hits	18
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CLC4F_HUMAN
θ value	5.27518 (rank : 101)	NC score	0.047029 (rank : 270)
Query Neighborhood Hits	140	Target Neighborhood Hits	513	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N1N0	Gene names	CLEC4F, CLECSF13
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13).

GRAP1_MOUSE
θ value	5.27518 (rank : 102)	NC score	0.064666 (rank : 84)
Query Neighborhood Hits	140	Target Neighborhood Hits	1234	Shared Neighborhood Hits	103
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

KMHN1_MOUSE
θ value	5.27518 (rank : 103)	NC score	0.055243 (rank : 187)
Query Neighborhood Hits	140	Target Neighborhood Hits	949	Shared Neighborhood Hits	86
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

LZTS1_MOUSE
θ value	5.27518 (rank : 104)	NC score	0.056611 (rank : 162)
Query Neighborhood Hits	140	Target Neighborhood Hits	540	Shared Neighborhood Hits	79
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MACF1_HUMAN
θ value	5.27518 (rank : 105)	NC score	0.060970 (rank : 118)
Query Neighborhood Hits	140	Target Neighborhood Hits	1341	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.068449 (rank : 66)
Query Neighborhood Hits	140	Target Neighborhood Hits	1321	Shared Neighborhood Hits	106
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

NEK11_HUMAN
θ value	5.27518 (rank : 107)	NC score	0.003927 (rank : 308)
Query Neighborhood Hits	140	Target Neighborhood Hits	1043	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

ROCK2_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.030824 (rank : 292)
Query Neighborhood Hits	140	Target Neighborhood Hits	2073	Shared Neighborhood Hits	105
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

SOCS4_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.037208 (rank : 287)
Query Neighborhood Hits	140	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXH5	Gene names	SOCS4, SOCS7
Domain Architecture
Description	Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7).

SOCS4_MOUSE
θ value	5.27518 (rank : 110)	NC score	0.039480 (rank : 282)
Query Neighborhood Hits	140	Target Neighborhood Hits	69	Shared Neighborhood Hits	19
SwissProt Accessions	Q91ZA6	Gene names	Socs4, Socs7
Domain Architecture
Description	Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7).

STK10_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.021975 (rank : 300)
Query Neighborhood Hits	140	Target Neighborhood Hits	1921	Shared Neighborhood Hits	103
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TPR_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.075180 (rank : 43)
Query Neighborhood Hits	140	Target Neighborhood Hits	1921	Shared Neighborhood Hits	108
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

BRE1A_MOUSE
θ value	6.88961 (rank : 113)	NC score	0.070598 (rank : 58)
Query Neighborhood Hits	140	Target Neighborhood Hits	1025	Shared Neighborhood Hits	90
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

CCHCR_HUMAN
θ value	6.88961 (rank : 114)	NC score	0.066967 (rank : 73)
Query Neighborhood Hits	140	Target Neighborhood Hits	717	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

CENPE_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.063473 (rank : 94)
Query Neighborhood Hits	140	Target Neighborhood Hits	2060	Shared Neighborhood Hits	111
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

EEA1_MOUSE
θ value	6.88961 (rank : 116)	NC score	0.065366 (rank : 80)
Query Neighborhood Hits	140	Target Neighborhood Hits	1637	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

GCC2_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.064995 (rank : 81)
Query Neighborhood Hits	140	Target Neighborhood Hits	1619	Shared Neighborhood Hits	105
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GOGA3_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.061157 (rank : 116)
Query Neighborhood Hits	140	Target Neighborhood Hits	1317	Shared Neighborhood Hits	99
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

MY18A_MOUSE
θ value	6.88961 (rank : 119)	NC score	0.054228 (rank : 200)
Query Neighborhood Hits	140	Target Neighborhood Hits	1989	Shared Neighborhood Hits	113
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SPTN4_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.030692 (rank : 293)
Query Neighborhood Hits	140	Target Neighborhood Hits	570	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

SRMS_HUMAN
θ value	6.88961 (rank : 121)	NC score	0.003391 (rank : 310)
Query Neighborhood Hits	140	Target Neighborhood Hits	946	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

TIF1B_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.008122 (rank : 304)
Query Neighborhood Hits	140	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

ZP1_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.006907 (rank : 306)
Query Neighborhood Hits	140	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	P60852	Gene names	ZP1
Domain Architecture	No domain graphic available
Description	Zona pellucida sperm-binding protein 1 precursor (Zona pellucida glycoprotein 1) (Zp-1).

APOE_MOUSE
θ value	8.99809 (rank : 124)	NC score	0.056331 (rank : 166)
Query Neighborhood Hits	140	Target Neighborhood Hits	319	Shared Neighborhood Hits	61
SwissProt Accessions	P08226	Gene names	Apoe
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

BAZ1B_MOUSE
θ value	8.99809 (rank : 125)	NC score	0.019678 (rank : 301)
Query Neighborhood Hits	140	Target Neighborhood Hits	394	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

CCD46_HUMAN
θ value	8.99809 (rank : 126)	NC score	0.062196 (rank : 101)
Query Neighborhood Hits	140	Target Neighborhood Hits	1430	Shared Neighborhood Hits	105
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

DYHC_HUMAN
θ value	8.99809 (rank : 127)	NC score	0.034654 (rank : 289)
Query Neighborhood Hits	140	Target Neighborhood Hits	733	Shared Neighborhood Hits	84
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
θ value	8.99809 (rank : 128)	NC score	0.034520 (rank : 290)
Query Neighborhood Hits	140	Target Neighborhood Hits	729	Shared Neighborhood Hits	83
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

HMMR_HUMAN
θ value	8.99809 (rank : 129)	NC score	0.073303 (rank : 51)
Query Neighborhood Hits	140	Target Neighborhood Hits	1082	Shared Neighborhood Hits	96
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

ITA2B_MOUSE
θ value	8.99809 (rank : 130)	NC score	0.002327 (rank : 311)
Query Neighborhood Hits	140	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QUM0, Q64229, Q9Z2M0	Gene names	Itga2b
Domain Architecture
Description	Integrin alpha-IIb precursor (Platelet membrane glycoprotein IIb) (GPalpha IIb) (GPIIb) (CD41 antigen) [Contains: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain].

MYH13_HUMAN
θ value	8.99809 (rank : 131)	NC score	0.046124 (rank : 275)
Query Neighborhood Hits	140	Target Neighborhood Hits	1504	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

PCQAP_HUMAN
θ value	8.99809 (rank : 132)	NC score	0.038955 (rank : 283)
Query Neighborhood Hits	140	Target Neighborhood Hits	549	Shared Neighborhood Hits	59
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

RUFY2_HUMAN
θ value	8.99809 (rank : 133)	NC score	0.055541 (rank : 179)
Query Neighborhood Hits	140	Target Neighborhood Hits	1208	Shared Neighborhood Hits	97
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

SDCG8_MOUSE
θ value	8.99809 (rank : 134)	NC score	0.057943 (rank : 141)
Query Neighborhood Hits	140	Target Neighborhood Hits	886	Shared Neighborhood Hits	85
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

SH22A_MOUSE
θ value	8.99809 (rank : 135)	NC score	0.061467 (rank : 112)
Query Neighborhood Hits	140	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

SOCS5_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.026315 (rank : 297)
Query Neighborhood Hits	140	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	O75159, Q8IYZ4	Gene names	SOCS5, CIS6, CISH5, CISH6, KIAA0671
Domain Architecture
Description	Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5) (Cytokine-inducible SH2 protein 6) (CIS-6).

SOCS5_MOUSE
θ value	8.99809 (rank : 137)	NC score	0.026569 (rank : 296)
Query Neighborhood Hits	140	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	O54928	Gene names	Socs5, Cish5
Domain Architecture
Description	Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5).

SPTB2_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.046267 (rank : 273)
Query Neighborhood Hits	140	Target Neighborhood Hits	748	Shared Neighborhood Hits	86
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SWP70_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.058026 (rank : 140)
Query Neighborhood Hits	140	Target Neighborhood Hits	973	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

TIF1B_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.007682 (rank : 305)
Query Neighborhood Hits	140	Target Neighborhood Hits	276	Shared Neighborhood Hits	15
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

ADIP_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.055508 (rank : 182)
Query Neighborhood Hits	140	Target Neighborhood Hits	470	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

ADIP_MOUSE
θ value	θ > 10 (rank : 142)	NC score	0.052301 (rank : 233)
Query Neighborhood Hits	140	Target Neighborhood Hits	415	Shared Neighborhood Hits	75
SwissProt Accessions	Q8VC66, Q8BG59, Q8C7X0, Q8K2F7	Gene names	Ssx2ip
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein).

AKAP9_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.063304 (rank : 95)
Query Neighborhood Hits	140	Target Neighborhood Hits	1710	Shared Neighborhood Hits	108
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

APOA4_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.051635 (rank : 247)
Query Neighborhood Hits	140	Target Neighborhood Hits	435	Shared Neighborhood Hits	63
SwissProt Accessions	P06728	Gene names	Apoa4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

AZI1_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.057489 (rank : 148)
Query Neighborhood Hits	140	Target Neighborhood Hits	1000	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

AZI1_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.060743 (rank : 120)
Query Neighborhood Hits	140	Target Neighborhood Hits	990	Shared Neighborhood Hits	93
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

BICD1_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.052319 (rank : 232)
Query Neighborhood Hits	140	Target Neighborhood Hits	844	Shared Neighborhood Hits	91
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BICD1_MOUSE
θ value	θ > 10 (rank : 148)	NC score	0.051666 (rank : 246)
Query Neighborhood Hits	140	Target Neighborhood Hits	837	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

BICD2_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.051406 (rank : 251)
Query Neighborhood Hits	140	Target Neighborhood Hits	864	Shared Neighborhood Hits	88
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

BPA1_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.052047 (rank : 239)
Query Neighborhood Hits	140	Target Neighborhood Hits	1477	Shared Neighborhood Hits	98
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BPAEA_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.052300 (rank : 234)
Query Neighborhood Hits	140	Target Neighborhood Hits	1369	Shared Neighborhood Hits	92
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BRE1B_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.055404 (rank : 184)
Query Neighborhood Hits	140	Target Neighborhood Hits	1040	Shared Neighborhood Hits	86
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

BRE1B_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.062072 (rank : 105)
Query Neighborhood Hits	140	Target Neighborhood Hits	970	Shared Neighborhood Hits	88
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

C102B_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.057644 (rank : 144)
Query Neighborhood Hits	140	Target Neighborhood Hits	542	Shared Neighborhood Hits	76
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

CA065_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.050625 (rank : 259)
Query Neighborhood Hits	140	Target Neighborhood Hits	469	Shared Neighborhood Hits	69
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

CALD1_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.054704 (rank : 195)
Query Neighborhood Hits	140	Target Neighborhood Hits	959	Shared Neighborhood Hits	86
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CARD9_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.051894 (rank : 243)
Query Neighborhood Hits	140	Target Neighborhood Hits	602	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CASP_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.055228 (rank : 188)
Query Neighborhood Hits	140	Target Neighborhood Hits	1131	Shared Neighborhood Hits	93
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CASP_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.052398 (rank : 230)
Query Neighborhood Hits	140	Target Neighborhood Hits	1152	Shared Neighborhood Hits	92
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CCD11_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.055987 (rank : 169)
Query Neighborhood Hits	140	Target Neighborhood Hits	498	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD13_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.058565 (rank : 133)
Query Neighborhood Hits	140	Target Neighborhood Hits	721	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

CCD19_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.064466 (rank : 86)
Query Neighborhood Hits	140	Target Neighborhood Hits	639	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CCD21_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.060371 (rank : 121)
Query Neighborhood Hits	140	Target Neighborhood Hits	1135	Shared Neighborhood Hits	95
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CCD27_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.080132 (rank : 33)
Query Neighborhood Hits	140	Target Neighborhood Hits	594	Shared Neighborhood Hits	82
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD27_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.068854 (rank : 64)
Query Neighborhood Hits	140	Target Neighborhood Hits	461	Shared Neighborhood Hits	68
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD41_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.055524 (rank : 180)
Query Neighborhood Hits	140	Target Neighborhood Hits	1139	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CCD41_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.058129 (rank : 138)
Query Neighborhood Hits	140	Target Neighborhood Hits	1399	Shared Neighborhood Hits	102
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

CCD46_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.057692 (rank : 143)
Query Neighborhood Hits	140	Target Neighborhood Hits	1405	Shared Neighborhood Hits	101
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CCD62_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.051460 (rank : 250)
Query Neighborhood Hits	140	Target Neighborhood Hits	631	Shared Neighborhood Hits	77
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

CCD91_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.059985 (rank : 126)
Query Neighborhood Hits	140	Target Neighborhood Hits	868	Shared Neighborhood Hits	85
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

CCD91_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.055756 (rank : 174)
Query Neighborhood Hits	140	Target Neighborhood Hits	699	Shared Neighborhood Hits	82
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

CCD96_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.056781 (rank : 156)
Query Neighborhood Hits	140	Target Neighborhood Hits	704	Shared Neighborhood Hits	80
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCDC6_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.056634 (rank : 161)
Query Neighborhood Hits	140	Target Neighborhood Hits	723	Shared Neighborhood Hits	79
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

CCHCR_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.062183 (rank : 102)
Query Neighborhood Hits	140	Target Neighborhood Hits	932	Shared Neighborhood Hits	95
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CE152_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.061483 (rank : 110)
Query Neighborhood Hits	140	Target Neighborhood Hits	976	Shared Neighborhood Hits	91
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CE290_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.064251 (rank : 90)
Query Neighborhood Hits	140	Target Neighborhood Hits	1553	Shared Neighborhood Hits	102
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CEP55_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.054045 (rank : 201)
Query Neighborhood Hits	140	Target Neighborhood Hits	504	Shared Neighborhood Hits	73
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

CEP55_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.052393 (rank : 231)
Query Neighborhood Hits	140	Target Neighborhood Hits	693	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

CEP57_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.050491 (rank : 262)
Query Neighborhood Hits	140	Target Neighborhood Hits	580	Shared Neighborhood Hits	74
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

CEP63_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.061480 (rank : 111)
Query Neighborhood Hits	140	Target Neighborhood Hits	1005	Shared Neighborhood Hits	95
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CEP70_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.056690 (rank : 159)
Query Neighborhood Hits	140	Target Neighborhood Hits	532	Shared Neighborhood Hits	85
SwissProt Accessions	Q6IQY5, Q9CRL9, Q9CTS4, Q9JIC1	Gene names	Cep70
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein).

CI039_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.055520 (rank : 181)
Query Neighborhood Hits	140	Target Neighborhood Hits	1171	Shared Neighborhood Hits	96
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CING_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.064442 (rank : 87)
Query Neighborhood Hits	140	Target Neighborhood Hits	1275	Shared Neighborhood Hits	97
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

CJ118_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.052081 (rank : 238)
Query Neighborhood Hits	140	Target Neighborhood Hits	937	Shared Neighborhood Hits	87
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

CJ118_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.060297 (rank : 122)
Query Neighborhood Hits	140	Target Neighborhood Hits	1132	Shared Neighborhood Hits	94
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CK5P2_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.053114 (rank : 216)
Query Neighborhood Hits	140	Target Neighborhood Hits	1433	Shared Neighborhood Hits	99
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CK5P2_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.055818 (rank : 173)
Query Neighborhood Hits	140	Target Neighborhood Hits	1151	Shared Neighborhood Hits	94
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CKAP4_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.052483 (rank : 228)
Query Neighborhood Hits	140	Target Neighborhood Hits	592	Shared Neighborhood Hits	74
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CKAP4_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.060087 (rank : 125)
Query Neighborhood Hits	140	Target Neighborhood Hits	596	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CN145_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.056268 (rank : 167)
Query Neighborhood Hits	140	Target Neighborhood Hits	1196	Shared Neighborhood Hits	98
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CN145_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.055848 (rank : 172)
Query Neighborhood Hits	140	Target Neighborhood Hits	916	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CNTRB_MOUSE
θ value	θ > 10 (rank : 192)	NC score	0.062152 (rank : 104)
Query Neighborhood Hits	140	Target Neighborhood Hits	1029	Shared Neighborhood Hits	92
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CR034_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.059154 (rank : 130)
Query Neighborhood Hits	140	Target Neighborhood Hits	538	Shared Neighborhood Hits	75
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

CR034_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.051877 (rank : 244)
Query Neighborhood Hits	140	Target Neighborhood Hits	643	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

CROCC_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.066159 (rank : 77)
Query Neighborhood Hits	140	Target Neighborhood Hits	1409	Shared Neighborhood Hits	101
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CROCC_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.068258 (rank : 67)
Query Neighborhood Hits	140	Target Neighborhood Hits	1460	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

CYLN2_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.061855 (rank : 109)
Query Neighborhood Hits	140	Target Neighborhood Hits	1004	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

CYLN2_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.063651 (rank : 93)
Query Neighborhood Hits	140	Target Neighborhood Hits	1002	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

CYTSA_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.052907 (rank : 219)
Query Neighborhood Hits	140	Target Neighborhood Hits	1138	Shared Neighborhood Hits	97
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

CYTSA_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.053650 (rank : 204)
Query Neighborhood Hits	140	Target Neighborhood Hits	1104	Shared Neighborhood Hits	95
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

DESP_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.061393 (rank : 115)
Query Neighborhood Hits	140	Target Neighborhood Hits	1470	Shared Neighborhood Hits	106
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DMD_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.050640 (rank : 258)
Query Neighborhood Hits	140	Target Neighborhood Hits	1135	Shared Neighborhood Hits	92
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

DMD_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.053582 (rank : 205)
Query Neighborhood Hits	140	Target Neighborhood Hits	1111	Shared Neighborhood Hits	92
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

DYNA_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.053412 (rank : 208)
Query Neighborhood Hits	140	Target Neighborhood Hits	1194	Shared Neighborhood Hits	92
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

DYNA_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.052877 (rank : 220)
Query Neighborhood Hits	140	Target Neighborhood Hits	1084	Shared Neighborhood Hits	90
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

EP15R_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.057304 (rank : 151)
Query Neighborhood Hits	140	Target Neighborhood Hits	1083	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

EP15R_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.057710 (rank : 142)
Query Neighborhood Hits	140	Target Neighborhood Hits	1135	Shared Neighborhood Hits	105
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

EP15_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.052485 (rank : 227)
Query Neighborhood Hits	140	Target Neighborhood Hits	1021	Shared Neighborhood Hits	102
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

ERC2_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.055735 (rank : 175)
Query Neighborhood Hits	140	Target Neighborhood Hits	1156	Shared Neighborhood Hits	95
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

ERC2_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.055938 (rank : 170)
Query Neighborhood Hits	140	Target Neighborhood Hits	1166	Shared Neighborhood Hits	96
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

EVPL_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.055419 (rank : 183)
Query Neighborhood Hits	140	Target Neighborhood Hits	895	Shared Neighborhood Hits	93
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

EVPL_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.059454 (rank : 128)
Query Neighborhood Hits	140	Target Neighborhood Hits	952	Shared Neighborhood Hits	96
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

FLIP1_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.059073 (rank : 132)
Query Neighborhood Hits	140	Target Neighborhood Hits	1405	Shared Neighborhood Hits	96
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FLIP1_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.057433 (rank : 149)
Query Neighborhood Hits	140	Target Neighborhood Hits	1176	Shared Neighborhood Hits	96
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

FYCO1_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.064361 (rank : 89)
Query Neighborhood Hits	140	Target Neighborhood Hits	1149	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

FYCO1_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.062178 (rank : 103)
Query Neighborhood Hits	140	Target Neighborhood Hits	1059	Shared Neighborhood Hits	102
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

GAS8_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.053153 (rank : 213)
Query Neighborhood Hits	140	Target Neighborhood Hits	819	Shared Neighborhood Hits	87
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GAS8_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.054765 (rank : 193)
Query Neighborhood Hits	140	Target Neighborhood Hits	622	Shared Neighborhood Hits	84
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

GCC1_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.058453 (rank : 136)
Query Neighborhood Hits	140	Target Neighborhood Hits	887	Shared Neighborhood Hits	92
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC1_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.058304 (rank : 137)
Query Neighborhood Hits	140	Target Neighborhood Hits	777	Shared Neighborhood Hits	87
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GOG8A_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.055127 (rank : 190)
Query Neighborhood Hits	140	Target Neighborhood Hits	635	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

GOGA1_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.068967 (rank : 63)
Query Neighborhood Hits	140	Target Neighborhood Hits	994	Shared Neighborhood Hits	98
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA2_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.074264 (rank : 47)
Query Neighborhood Hits	140	Target Neighborhood Hits	856	Shared Neighborhood Hits	92
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

GOGA3_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.062592 (rank : 99)
Query Neighborhood Hits	140	Target Neighborhood Hits	1437	Shared Neighborhood Hits	102
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

GOGA5_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.056848 (rank : 154)
Query Neighborhood Hits	140	Target Neighborhood Hits	1168	Shared Neighborhood Hits	98
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

GOGA5_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.061433 (rank : 114)
Query Neighborhood Hits	140	Target Neighborhood Hits	1434	Shared Neighborhood Hits	100
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

GOGA6_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.063147 (rank : 96)
Query Neighborhood Hits	140	Target Neighborhood Hits	1007	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

GRAP1_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.060828 (rank : 119)
Query Neighborhood Hits	140	Target Neighborhood Hits	944	Shared Neighborhood Hits	92
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

HAP1_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.051119 (rank : 253)
Query Neighborhood Hits	140	Target Neighborhood Hits	606	Shared Neighborhood Hits	87
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

HOOK1_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.056650 (rank : 160)
Query Neighborhood Hits	140	Target Neighborhood Hits	942	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

HOOK1_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.055919 (rank : 171)
Query Neighborhood Hits	140	Target Neighborhood Hits	910	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

HOOK2_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.057564 (rank : 147)
Query Neighborhood Hits	140	Target Neighborhood Hits	714	Shared Neighborhood Hits	92
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

HOOK2_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.054711 (rank : 194)
Query Neighborhood Hits	140	Target Neighborhood Hits	736	Shared Neighborhood Hits	91
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

HOOK3_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.050745 (rank : 256)
Query Neighborhood Hits	140	Target Neighborhood Hits	1070	Shared Neighborhood Hits	94
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

IFT74_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.071922 (rank : 52)
Query Neighborhood Hits	140	Target Neighborhood Hits	949	Shared Neighborhood Hits	90
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT74_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.073704 (rank : 49)
Query Neighborhood Hits	140	Target Neighborhood Hits	939	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

IFT81_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.053399 (rank : 209)
Query Neighborhood Hits	140	Target Neighborhood Hits	893	Shared Neighborhood Hits	89
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

IFT81_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.054630 (rank : 196)
Query Neighborhood Hits	140	Target Neighborhood Hits	959	Shared Neighborhood Hits	88
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

INCE_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.051814 (rank : 245)
Query Neighborhood Hits	140	Target Neighborhood Hits	903	Shared Neighborhood Hits	89
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

INVO_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.062574 (rank : 100)
Query Neighborhood Hits	140	Target Neighborhood Hits	636	Shared Neighborhood Hits	76
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

INVO_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.050374 (rank : 264)
Query Neighborhood Hits	140	Target Neighborhood Hits	474	Shared Neighborhood Hits	69
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

K0552_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.052207 (rank : 237)
Query Neighborhood Hits	140	Target Neighborhood Hits	442	Shared Neighborhood Hits	74
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

K0555_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.056554 (rank : 164)
Query Neighborhood Hits	140	Target Neighborhood Hits	880	Shared Neighborhood Hits	89
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

KMHN1_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.057356 (rank : 150)
Query Neighborhood Hits	140	Target Neighborhood Hits	950	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

KNTC2_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.054930 (rank : 192)
Query Neighborhood Hits	140	Target Neighborhood Hits	673	Shared Neighborhood Hits	80
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

KNTC2_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.055643 (rank : 177)
Query Neighborhood Hits	140	Target Neighborhood Hits	692	Shared Neighborhood Hits	79
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

KTN1_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.073707 (rank : 48)
Query Neighborhood Hits	140	Target Neighborhood Hits	1197	Shared Neighborhood Hits	100
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

KTN1_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.061977 (rank : 106)
Query Neighborhood Hits	140	Target Neighborhood Hits	1324	Shared Neighborhood Hits	98
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

LIPA1_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.052020 (rank : 240)
Query Neighborhood Hits	140	Target Neighborhood Hits	1294	Shared Neighborhood Hits	92
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

LRC45_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.056760 (rank : 157)
Query Neighborhood Hits	140	Target Neighborhood Hits	933	Shared Neighborhood Hits	94
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC45_MOUSE
θ value	θ > 10 (rank : 251)	NC score	0.051481 (rank : 249)
Query Neighborhood Hits	140	Target Neighborhood Hits	959	Shared Neighborhood Hits	86
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRRF2_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.050122 (rank : 266)
Query Neighborhood Hits	140	Target Neighborhood Hits	791	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

LUZP1_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.052423 (rank : 229)
Query Neighborhood Hits	140	Target Neighborhood Hits	739	Shared Neighborhood Hits	86
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

LUZP1_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.051951 (rank : 242)
Query Neighborhood Hits	140	Target Neighborhood Hits	940	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MACF1_MOUSE
θ value	θ > 10 (rank : 255)	NC score	0.052694 (rank : 223)
Query Neighborhood Hits	140	Target Neighborhood Hits	1313	Shared Neighborhood Hits	96
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MD1L1_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.057570 (rank : 146)
Query Neighborhood Hits	140	Target Neighborhood Hits	893	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

MD1L1_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.060161 (rank : 124)
Query Neighborhood Hits	140	Target Neighborhood Hits	1001	Shared Neighborhood Hits	96
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

MIPO1_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.053233 (rank : 211)
Query Neighborhood Hits	140	Target Neighborhood Hits	486	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

MPP9_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.055708 (rank : 176)
Query Neighborhood Hits	140	Target Neighborhood Hits	529	Shared Neighborhood Hits	69
SwissProt Accessions	Q99550, Q9H976	Gene names	MPHOSPH9, MPP9
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 9.

NAF1_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.062605 (rank : 98)
Query Neighborhood Hits	140	Target Neighborhood Hits	937	Shared Neighborhood Hits	98
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

NAF1_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.063719 (rank : 91)
Query Neighborhood Hits	140	Target Neighborhood Hits	852	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

NEMO_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.056838 (rank : 155)
Query Neighborhood Hits	140	Target Neighborhood Hits	820	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

NIN_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.067768 (rank : 71)
Query Neighborhood Hits	140	Target Neighborhood Hits	1416	Shared Neighborhood Hits	102
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

NIN_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.064616 (rank : 85)
Query Neighborhood Hits	140	Target Neighborhood Hits	1376	Shared Neighborhood Hits	99
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

OFD1_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.051604 (rank : 248)
Query Neighborhood Hits	140	Target Neighborhood Hits	753	Shared Neighborhood Hits	81
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

OPTN_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.055298 (rank : 185)
Query Neighborhood Hits	140	Target Neighborhood Hits	827	Shared Neighborhood Hits	83
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

OPTN_MOUSE
θ value	θ > 10 (rank : 267)	NC score	0.055139 (rank : 189)
Query Neighborhood Hits	140	Target Neighborhood Hits	1120	Shared Neighborhood Hits	91
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

PCNT_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.067890 (rank : 70)
Query Neighborhood Hits	140	Target Neighborhood Hits	1207	Shared Neighborhood Hits	99
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

PEPL_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.057596 (rank : 145)
Query Neighborhood Hits	140	Target Neighborhood Hits	1141	Shared Neighborhood Hits	91
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PEPL_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.057221 (rank : 153)
Query Neighborhood Hits	140	Target Neighborhood Hits	1105	Shared Neighborhood Hits	90
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PIBF1_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.058108 (rank : 139)
Query Neighborhood Hits	140	Target Neighborhood Hits	1041	Shared Neighborhood Hits	92
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

PININ_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.053759 (rank : 203)
Query Neighborhood Hits	140	Target Neighborhood Hits	753	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

PININ_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.052015 (rank : 241)
Query Neighborhood Hits	140	Target Neighborhood Hits	777	Shared Neighborhood Hits	73
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

RABE1_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.065697 (rank : 78)
Query Neighborhood Hits	140	Target Neighborhood Hits	1104	Shared Neighborhood Hits	99
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.066204 (rank : 76)
Query Neighborhood Hits	140	Target Neighborhood Hits	1105	Shared Neighborhood Hits	100
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

RABE2_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.053147 (rank : 214)
Query Neighborhood Hits	140	Target Neighborhood Hits	545	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

RAD50_MOUSE
θ value	θ > 10 (rank : 277)	NC score	0.064837 (rank : 82)
Query Neighborhood Hits	140	Target Neighborhood Hits	1366	Shared Neighborhood Hits	104
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RB6I2_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.056402 (rank : 165)
Query Neighborhood Hits	140	Target Neighborhood Hits	1584	Shared Neighborhood Hits	100
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

RB6I2_MOUSE
θ value	θ > 10 (rank : 279)	NC score	0.055059 (rank : 191)
Query Neighborhood Hits	140	Target Neighborhood Hits	1433	Shared Neighborhood Hits	98
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

RBCC1_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.055605 (rank : 178)
Query Neighborhood Hits	140	Target Neighborhood Hits	1023	Shared Neighborhood Hits	93
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

RBCC1_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.052245 (rank : 235)
Query Neighborhood Hits	140	Target Neighborhood Hits	1048	Shared Neighborhood Hits	90
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

RIMB1_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.061898 (rank : 108)
Query Neighborhood Hits	140	Target Neighborhood Hits	1479	Shared Neighborhood Hits	92
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RPGR1_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.064428 (rank : 88)
Query Neighborhood Hits	140	Target Neighborhood Hits	578	Shared Neighborhood Hits	79
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

RRBP1_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.053421 (rank : 207)
Query Neighborhood Hits	140	Target Neighborhood Hits	1306	Shared Neighborhood Hits	97
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

RUFY1_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.052238 (rank : 236)
Query Neighborhood Hits	140	Target Neighborhood Hits	765	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

RUFY2_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.052542 (rank : 225)
Query Neighborhood Hits	140	Target Neighborhood Hits	820	Shared Neighborhood Hits	89
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

SAS6_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.054517 (rank : 197)
Query Neighborhood Hits	140	Target Neighborhood Hits	791	Shared Neighborhood Hits	86
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

SAS6_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.060278 (rank : 123)
Query Neighborhood Hits	140	Target Neighborhood Hits	931	Shared Neighborhood Hits	96
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

SDCG8_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.059137 (rank : 131)
Query Neighborhood Hits	140	Target Neighborhood Hits	1002	Shared Neighborhood Hits	90
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

SMC2_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.050843 (rank : 255)
Query Neighborhood Hits	140	Target Neighborhood Hits	1405	Shared Neighborhood Hits	102
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SMC3_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.053022 (rank : 218)
Query Neighborhood Hits	140	Target Neighborhood Hits	1186	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.053213 (rank : 212)
Query Neighborhood Hits	140	Target Neighborhood Hits	1187	Shared Neighborhood Hits	100
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SPAG5_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.053144 (rank : 215)
Query Neighborhood Hits	140	Target Neighborhood Hits	625	Shared Neighborhood Hits	83
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

SPAG5_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.056716 (rank : 158)
Query Neighborhood Hits	140	Target Neighborhood Hits	612	Shared Neighborhood Hits	81
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

SYCP1_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.054494 (rank : 198)
Query Neighborhood Hits	140	Target Neighborhood Hits	1313	Shared Neighborhood Hits	93
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYCP1_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.053541 (rank : 206)
Query Neighborhood Hits	140	Target Neighborhood Hits	1456	Shared Neighborhood Hits	94
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

SYNE1_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.059683 (rank : 127)
Query Neighborhood Hits	140	Target Neighborhood Hits	1484	Shared Neighborhood Hits	98
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

SYNE2_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.050551 (rank : 261)
Query Neighborhood Hits	140	Target Neighborhood Hits	1323	Shared Neighborhood Hits	95
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

T3JAM_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.051146 (rank : 252)
Query Neighborhood Hits	140	Target Neighborhood Hits	533	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

TAXB1_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.052729 (rank : 221)
Query Neighborhood Hits	140	Target Neighborhood Hits	829	Shared Neighborhood Hits	85
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

TAXB1_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.051050 (rank : 254)
Query Neighborhood Hits	140	Target Neighborhood Hits	886	Shared Neighborhood Hits	85
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

TEX9_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.050616 (rank : 260)
Query Neighborhood Hits	140	Target Neighborhood Hits	581	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

TMF1_HUMAN
θ value	θ > 10 (rank : 303)	NC score	0.058543 (rank : 135)
Query Neighborhood Hits	140	Target Neighborhood Hits	987	Shared Neighborhood Hits	84
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

TNIP3_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.053092 (rank : 217)
Query Neighborhood Hits	140	Target Neighborhood Hits	511	Shared Neighborhood Hits	76
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

TSC1_HUMAN
θ value	θ > 10 (rank : 305)	NC score	0.053986 (rank : 202)
Query Neighborhood Hits	140	Target Neighborhood Hits	765	Shared Neighborhood Hits	89
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

TUFT1_MOUSE
θ value	θ > 10 (rank : 306)	NC score	0.054277 (rank : 199)
Query Neighborhood Hits	140	Target Neighborhood Hits	732	Shared Neighborhood Hits	82
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

UACA_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.050469 (rank : 263)
Query Neighborhood Hits	140	Target Neighborhood Hits	1622	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

UACA_MOUSE
θ value	θ > 10 (rank : 308)	NC score	0.053378 (rank : 210)
Query Neighborhood Hits	140	Target Neighborhood Hits	1620	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

VDP_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.052699 (rank : 222)
Query Neighborhood Hits	140	Target Neighborhood Hits	645	Shared Neighborhood Hits	79
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

XE7_HUMAN
θ value	θ > 10 (rank : 310)	NC score	0.055271 (rank : 186)
Query Neighborhood Hits	140	Target Neighborhood Hits	738	Shared Neighborhood Hits	85
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

ZN291_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.052492 (rank : 226)
Query Neighborhood Hits	140	Target Neighborhood Hits	647	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

Hits sorted by NC score

STA5A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	140	Target Neighborhood Hits	140	Shared Neighborhood Hits	140
SwissProt Accessions	P42229	Gene names	STAT5A, STAT5
Domain Architecture
Description	Signal transducer and activator of transcription 5A.

STA5A_MOUSE
NC score	0.995448 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	140	Target Neighborhood Hits	128	Shared Neighborhood Hits	102
SwissProt Accessions	P42230	Gene names	Stat5a, Mgf, Mpf
Domain Architecture
Description	Signal transducer and activator of transcription 5A (Mammary gland factor).

STA5B_HUMAN
NC score	0.994214 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	140	Target Neighborhood Hits	103	Shared Neighborhood Hits	89
SwissProt Accessions	P51692, Q8WWS8	Gene names	STAT5B
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STA5B_MOUSE
NC score	0.993426 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	140	Target Neighborhood Hits	124	Shared Neighborhood Hits	95
SwissProt Accessions	P42232, Q541Q5, Q60804, Q8K3Q1, Q9JKM1	Gene names	Stat5b
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STAT6_MOUSE
NC score	0.942533 (rank : 5)	θ value	6.21357e-126 (rank : 6)
Query Neighborhood Hits	140	Target Neighborhood Hits	78	Shared Neighborhood Hits	21
SwissProt Accessions	P52633	Gene names	Stat6
Domain Architecture
Description	Signal transducer and transcription activator 6.

STAT6_HUMAN
NC score	0.936135 (rank : 6)	θ value	3.64273e-126 (rank : 5)
Query Neighborhood Hits	140	Target Neighborhood Hits	132	Shared Neighborhood Hits	24
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

STAT4_MOUSE
NC score	0.894557 (rank : 7)	θ value	4.51533e-76 (rank : 10)
Query Neighborhood Hits	140	Target Neighborhood Hits	73	Shared Neighborhood Hits	32
SwissProt Accessions	P42228	Gene names	Stat4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STAT4_HUMAN
NC score	0.889748 (rank : 8)	θ value	1.65806e-78 (rank : 9)
Query Neighborhood Hits	140	Target Neighborhood Hits	91	Shared Neighborhood Hits	30
SwissProt Accessions	Q14765, Q96NZ6	Gene names	STAT4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STAT3_HUMAN
NC score	0.887263 (rank : 9)	θ value	2.91998e-83 (rank : 7)
Query Neighborhood Hits	140	Target Neighborhood Hits	155	Shared Neighborhood Hits	42
SwissProt Accessions	P40763, O14916, Q9BW54	Gene names	STAT3, APRF
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT3_MOUSE
NC score	0.887261 (rank : 10)	θ value	2.91998e-83 (rank : 8)
Query Neighborhood Hits	140	Target Neighborhood Hits	155	Shared Neighborhood Hits	42
SwissProt Accessions	P42227	Gene names	Stat3, Aprf
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT1_HUMAN
NC score	0.883141 (rank : 11)	θ value	1.45253e-74 (rank : 11)
Query Neighborhood Hits	140	Target Neighborhood Hits	128	Shared Neighborhood Hits	50
SwissProt Accessions	P42224	Gene names	STAT1
Domain Architecture
Description	Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84).

STAT1_MOUSE
NC score	0.879778 (rank : 12)	θ value	6.10265e-73 (rank : 12)
Query Neighborhood Hits	140	Target Neighborhood Hits	151	Shared Neighborhood Hits	49
SwissProt Accessions	P42225	Gene names	Stat1
Domain Architecture
Description	Signal transducer and activator of transcription 1.

STAT2_HUMAN
NC score	0.867706 (rank : 13)	θ value	3.1488e-53 (rank : 13)
Query Neighborhood Hits	140	Target Neighborhood Hits	99	Shared Neighborhood Hits	31
SwissProt Accessions	P52630, Q16430, Q16431	Gene names	STAT2
Domain Architecture
Description	Signal transducer and activator of transcription 2 (p113).

STAT2_MOUSE
NC score	0.813506 (rank : 14)	θ value	2.18568e-46 (rank : 14)
Query Neighborhood Hits	140	Target Neighborhood Hits	175	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

SH22A_HUMAN
NC score	0.114780 (rank : 15)	θ value	0.279714 (rank : 42)
Query Neighborhood Hits	140	Target Neighborhood Hits	144	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

GOGB1_HUMAN
NC score	0.104871 (rank : 16)	θ value	1.43324e-05 (rank : 15)
Query Neighborhood Hits	140	Target Neighborhood Hits	2297	Shared Neighborhood Hits	115
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CI093_HUMAN
NC score	0.100539 (rank : 17)	θ value	0.00228821 (rank : 16)
Query Neighborhood Hits	140	Target Neighborhood Hits	1088	Shared Neighborhood Hits	99
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

GOGA2_MOUSE
NC score	0.093705 (rank : 18)	θ value	0.0563607 (rank : 21)
Query Neighborhood Hits	140	Target Neighborhood Hits	944	Shared Neighborhood Hits	103
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

RIMB1_MOUSE
NC score	0.093401 (rank : 19)	θ value	0.0193708 (rank : 19)
Query Neighborhood Hits	140	Target Neighborhood Hits	1376	Shared Neighborhood Hits	98
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

PCNT_HUMAN
NC score	0.093044 (rank : 20)	θ value	0.0961366 (rank : 28)
Query Neighborhood Hits	140	Target Neighborhood Hits	1551	Shared Neighborhood Hits	106
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

CP135_HUMAN
NC score	0.090865 (rank : 21)	θ value	0.00390308 (rank : 17)
Query Neighborhood Hits	140	Target Neighborhood Hits	1290	Shared Neighborhood Hits	102
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

TFAP4_HUMAN
NC score	0.090048 (rank : 22)	θ value	0.279714 (rank : 43)
Query Neighborhood Hits	140	Target Neighborhood Hits	289	Shared Neighborhood Hits	58
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

TRIPB_HUMAN
NC score	0.089662 (rank : 23)	θ value	0.0961366 (rank : 29)
Query Neighborhood Hits	140	Target Neighborhood Hits	1587	Shared Neighborhood Hits	108
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CP250_HUMAN
NC score	0.087790 (rank : 24)	θ value	0.125558 (rank : 30)
Query Neighborhood Hits	140	Target Neighborhood Hits	1805	Shared Neighborhood Hits	110
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

GOGA4_MOUSE
NC score	0.087242 (rank : 25)	θ value	0.0961366 (rank : 27)
Query Neighborhood Hits	140	Target Neighborhood Hits	1939	Shared Neighborhood Hits	114
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

CF060_HUMAN
NC score	0.085911 (rank : 26)	θ value	0.21417 (rank : 37)
Query Neighborhood Hits	140	Target Neighborhood Hits	1270	Shared Neighborhood Hits	99
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

CCD11_HUMAN
NC score	0.084682 (rank : 27)	θ value	1.06291 (rank : 61)
Query Neighborhood Hits	140	Target Neighborhood Hits	822	Shared Neighborhood Hits	96
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CENPF_HUMAN
NC score	0.084495 (rank : 28)	θ value	0.0961366 (rank : 26)
Query Neighborhood Hits	140	Target Neighborhood Hits	1932	Shared Neighborhood Hits	113
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

HSH2D_MOUSE
NC score	0.084196 (rank : 29)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	140	Target Neighborhood Hits	124	Shared Neighborhood Hits	25
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

P55G_MOUSE
NC score	0.083086 (rank : 30)	θ value	0.47712 (rank : 53)
Query Neighborhood Hits	140	Target Neighborhood Hits	401	Shared Neighborhood Hits	72
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

CCD21_HUMAN
NC score	0.082155 (rank : 31)	θ value	0.21417 (rank : 36)
Query Neighborhood Hits	140	Target Neighborhood Hits	1228	Shared Neighborhood Hits	101
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CP135_MOUSE
NC score	0.081639 (rank : 32)	θ value	1.38821 (rank : 66)
Query Neighborhood Hits	140	Target Neighborhood Hits	1278	Shared Neighborhood Hits	104
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CCD27_HUMAN
NC score	0.080132 (rank : 33)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	140	Target Neighborhood Hits	594	Shared Neighborhood Hits	82
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

P55G_HUMAN
NC score	0.079519 (rank : 34)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	140	Target Neighborhood Hits	451	Shared Neighborhood Hits	74
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

BRE1A_HUMAN
NC score	0.078243 (rank : 35)	θ value	0.0961366 (rank : 24)
Query Neighborhood Hits	140	Target Neighborhood Hits	1071	Shared Neighborhood Hits	91
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

HIP1_HUMAN
NC score	0.078188 (rank : 36)	θ value	0.125558 (rank : 31)
Query Neighborhood Hits	140	Target Neighborhood Hits	1016	Shared Neighborhood Hits	92
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

CNTRB_HUMAN
NC score	0.077916 (rank : 37)	θ value	0.813845 (rank : 55)
Query Neighborhood Hits	140	Target Neighborhood Hits	690	Shared Neighborhood Hits	94
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CP250_MOUSE
NC score	0.077681 (rank : 38)	θ value	0.21417 (rank : 39)
Query Neighborhood Hits	140	Target Neighborhood Hits	1583	Shared Neighborhood Hits	107
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

GOGA4_HUMAN
NC score	0.077193 (rank : 39)	θ value	0.47712 (rank : 49)
Query Neighborhood Hits	140	Target Neighborhood Hits	2034	Shared Neighborhood Hits	114
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

REST_MOUSE
NC score	0.077063 (rank : 40)	θ value	0.00509761 (rank : 18)
Query Neighborhood Hits	140	Target Neighborhood Hits	1506	Shared Neighborhood Hits	100
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

NUMA1_HUMAN
NC score	0.076711 (rank : 41)	θ value	1.06291 (rank : 64)
Query Neighborhood Hits	140	Target Neighborhood Hits	1523	Shared Neighborhood Hits	105
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

CCD45_MOUSE
NC score	0.075367 (rank : 42)	θ value	0.365318 (rank : 45)
Query Neighborhood Hits	140	Target Neighborhood Hits	663	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

TPR_HUMAN
NC score	0.075180 (rank : 43)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	140	Target Neighborhood Hits	1921	Shared Neighborhood Hits	108
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

P85B_HUMAN
NC score	0.074912 (rank : 44)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	140	Target Neighborhood Hits	543	Shared Neighborhood Hits	77
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
NC score	0.074856 (rank : 45)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	140	Target Neighborhood Hits	519	Shared Neighborhood Hits	78
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

GOGA1_HUMAN
NC score	0.074582 (rank : 46)	θ value	0.279714 (rank : 41)
Query Neighborhood Hits	140	Target Neighborhood Hits	1222	Shared Neighborhood Hits	102
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA2_HUMAN
NC score	0.074264 (rank : 47)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	140	Target Neighborhood Hits	856	Shared Neighborhood Hits	92
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

KTN1_HUMAN
NC score	0.073707 (rank : 48)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	140	Target Neighborhood Hits	1197	Shared Neighborhood Hits	100
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

IFT74_MOUSE
NC score	0.073704 (rank : 49)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	140	Target Neighborhood Hits	939	Shared Neighborhood Hits	93
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

EEA1_HUMAN
NC score	0.073565 (rank : 50)	θ value	1.38821 (rank : 67)
Query Neighborhood Hits	140	Target Neighborhood Hits	1796	Shared Neighborhood Hits	110
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

HMMR_HUMAN
NC score	0.073303 (rank : 51)	θ value	8.99809 (rank : 129)
Query Neighborhood Hits	140	Target Neighborhood Hits	1082	Shared Neighborhood Hits	96
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

IFT74_HUMAN
NC score	0.071922 (rank : 52)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	140	Target Neighborhood Hits	949	Shared Neighborhood Hits	90
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

HIP1R_HUMAN
NC score	0.071574 (rank : 53)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	140	Target Neighborhood Hits	809	Shared Neighborhood Hits	91
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

NEMO_MOUSE
NC score	0.070955 (rank : 54)	θ value	0.125558 (rank : 32)
Query Neighborhood Hits	140	Target Neighborhood Hits	658	Shared Neighborhood Hits	92
SwissProt Accessions	O88522	Gene names	Ikbkg, Nemo
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3).

TRHY_HUMAN
NC score	0.070951 (rank : 55)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	140	Target Neighborhood Hits	1385	Shared Neighborhood Hits	95
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

HSH2D_HUMAN
NC score	0.070834 (rank : 56)	θ value	0.47712 (rank : 51)
Query Neighborhood Hits	140	Target Neighborhood Hits	159	Shared Neighborhood Hits	22
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

HIP1R_MOUSE
NC score	0.070642 (rank : 57)	θ value	1.81305 (rank : 78)
Query Neighborhood Hits	140	Target Neighborhood Hits	959	Shared Neighborhood Hits	95
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

BRE1A_MOUSE
NC score	0.070598 (rank : 58)	θ value	6.88961 (rank : 113)
Query Neighborhood Hits	140	Target Neighborhood Hits	1025	Shared Neighborhood Hits	90
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

HMMR_MOUSE
NC score	0.070059 (rank : 59)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	140	Target Neighborhood Hits	1178	Shared Neighborhood Hits	103
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

RBP24_HUMAN
NC score	0.069878 (rank : 60)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	140	Target Neighborhood Hits	1559	Shared Neighborhood Hits	107
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

RABE2_MOUSE
NC score	0.069552 (rank : 61)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	140	Target Neighborhood Hits	598	Shared Neighborhood Hits	95
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

GCC2_HUMAN
NC score	0.069487 (rank : 62)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	140	Target Neighborhood Hits	1558	Shared Neighborhood Hits	106
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GOGA1_MOUSE
NC score	0.068967 (rank : 63)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	140	Target Neighborhood Hits	994	Shared Neighborhood Hits	98
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

CCD27_MOUSE
NC score	0.068854 (rank : 64)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	140	Target Neighborhood Hits	461	Shared Neighborhood Hits	68
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CING_MOUSE
NC score	0.068630 (rank : 65)	θ value	0.21417 (rank : 38)
Query Neighborhood Hits	140	Target Neighborhood Hits	1432	Shared Neighborhood Hits	105
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

MACF4_HUMAN
NC score	0.068449 (rank : 66)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	140	Target Neighborhood Hits	1321	Shared Neighborhood Hits	106
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

CROCC_MOUSE
NC score	0.068258 (rank : 67)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	140	Target Neighborhood Hits	1460	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

REST_HUMAN
NC score	0.067970 (rank : 68)	θ value	0.0563607 (rank : 22)
Query Neighborhood Hits	140	Target Neighborhood Hits	1605	Shared Neighborhood Hits	100
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

CCD39_MOUSE
NC score	0.067940 (rank : 69)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	140	Target Neighborhood Hits	1026	Shared Neighborhood Hits	94
SwissProt Accessions	Q9D5Y1, Q8CDG6	Gene names	Ccdc39, D3Ertd789e
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

PCNT_MOUSE
NC score	0.067890 (rank : 70)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	140	Target Neighborhood Hits	1207	Shared Neighborhood Hits	99
SwissProt Accessions	P48725	Gene names	Pcnt, Pcnt2
Domain Architecture	No domain graphic available
Description	Pericentrin.

NIN_HUMAN
NC score	0.067768 (rank : 71)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	140	Target Neighborhood Hits	1416	Shared Neighborhood Hits	102
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

RAD50_HUMAN
NC score	0.067736 (rank : 72)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	140	Target Neighborhood Hits	1317	Shared Neighborhood Hits	99
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

CCHCR_HUMAN
NC score	0.066967 (rank : 73)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	140	Target Neighborhood Hits	717	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

BPAEA_MOUSE
NC score	0.066527 (rank : 74)	θ value	0.365318 (rank : 44)
Query Neighborhood Hits	140	Target Neighborhood Hits	1480	Shared Neighborhood Hits	106
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

TUFT1_HUMAN
NC score	0.066392 (rank : 75)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	140	Target Neighborhood Hits	686	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

RABE1_MOUSE
NC score	0.066204 (rank : 76)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	140	Target Neighborhood Hits	1105	Shared Neighborhood Hits	100
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

CROCC_HUMAN
NC score	0.066159 (rank : 77)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	140	Target Neighborhood Hits	1409	Shared Neighborhood Hits	101
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

RABE1_HUMAN
NC score	0.065697 (rank : 78)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	140	Target Neighborhood Hits	1104	Shared Neighborhood Hits	99
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

SWP70_MOUSE
NC score	0.065373 (rank : 79)	θ value	1.38821 (rank : 76)
Query Neighborhood Hits	140	Target Neighborhood Hits	1097	Shared Neighborhood Hits	95
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

EEA1_MOUSE
NC score	0.065366 (rank : 80)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	140	Target Neighborhood Hits	1637	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

GCC2_MOUSE
NC score	0.064995 (rank : 81)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	140	Target Neighborhood Hits	1619	Shared Neighborhood Hits	105
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

RAD50_MOUSE
NC score	0.064837 (rank : 82)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	140	Target Neighborhood Hits	1366	Shared Neighborhood Hits	104
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

INCE_HUMAN
NC score	0.064720 (rank : 83)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	140	Target Neighborhood Hits	978	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

GRAP1_MOUSE
NC score	0.064666 (rank : 84)	θ value	5.27518 (rank : 102)
Query Neighborhood Hits	140	Target Neighborhood Hits	1234	Shared Neighborhood Hits	103
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

NIN_MOUSE
NC score	0.064616 (rank : 85)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	140	Target Neighborhood Hits	1376	Shared Neighborhood Hits	99
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

CCD19_HUMAN
NC score	0.064466 (rank : 86)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	140	Target Neighborhood Hits	639	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UL16	Gene names	CCDC19, NESG1
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 19 (Nasopharyngeal epithelium- specific protein 1).

CING_HUMAN
NC score	0.064442 (rank : 87)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	140	Target Neighborhood Hits	1275	Shared Neighborhood Hits	97
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

RPGR1_HUMAN
NC score	0.064428 (rank : 88)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	140	Target Neighborhood Hits	578	Shared Neighborhood Hits	79
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

FYCO1_HUMAN
NC score	0.064361 (rank : 89)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	140	Target Neighborhood Hits	1149	Shared Neighborhood Hits	102
SwissProt Accessions	Q9BQS8, Q3MJE6, Q86T41, Q86TB1, Q8TEF9, Q96IV5, Q9H8P9	Gene names	FYCO1, ZFYVE7
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7).

CE290_HUMAN
NC score	0.064251 (rank : 90)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	140	Target Neighborhood Hits	1553	Shared Neighborhood Hits	102
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

NAF1_MOUSE
NC score	0.063719 (rank : 91)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	140	Target Neighborhood Hits	852	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

PCQAP_MOUSE
NC score	0.063682 (rank : 92)	θ value	0.163984 (rank : 35)
Query Neighborhood Hits	140	Target Neighborhood Hits	506	Shared Neighborhood Hits	53
SwissProt Accessions	Q924H2	Gene names	Pcqap
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (mPcqap).

CYLN2_MOUSE
NC score	0.063651 (rank : 93)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	140	Target Neighborhood Hits	1002	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

CENPE_HUMAN
NC score	0.063473 (rank : 94)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	140	Target Neighborhood Hits	2060	Shared Neighborhood Hits	111
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

AKAP9_HUMAN
NC score	0.063304 (rank : 95)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	140	Target Neighborhood Hits	1710	Shared Neighborhood Hits	108
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

GOGA6_HUMAN
NC score	0.063147 (rank : 96)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	140	Target Neighborhood Hits	1007	Shared Neighborhood Hits	97
SwissProt Accessions	Q9NYA3, Q9NYA7	Gene names	GOLGA6, GLP
Domain Architecture
Description	Golgin subfamily A member 6 (Golgin linked to PML) (Golgin-like protein).

CCD39_HUMAN
NC score	0.062954 (rank : 97)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	140	Target Neighborhood Hits	868	Shared Neighborhood Hits	86
SwissProt Accessions	Q9UFE4	Gene names	CCDC39
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 39.

NAF1_HUMAN
NC score	0.062605 (rank : 98)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	140	Target Neighborhood Hits	937	Shared Neighborhood Hits	98
SwissProt Accessions	Q15025, O76008, Q96EL9, Q99833, Q9H1J3	Gene names	TNIP1, KIAA0113, NAF1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (HIV-1 Nef-interacting protein) (Virion-associated nuclear shuttling protein) (VAN) (hVAN) (Nip40-1).

GOGA3_MOUSE
NC score	0.062592 (rank : 99)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	140	Target Neighborhood Hits	1437	Shared Neighborhood Hits	102
SwissProt Accessions	P55937, Q80VF5, Q8CCK4, Q9QYT2, Q9QYT3	Gene names	Golga3, Mea2
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2).

INVO_HUMAN
NC score	0.062574 (rank : 100)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	140	Target Neighborhood Hits	636	Shared Neighborhood Hits	76
SwissProt Accessions	P07476	Gene names	IVL
Domain Architecture	No domain graphic available
Description	Involucrin.

CCD46_HUMAN
NC score	0.062196 (rank : 101)	θ value	8.99809 (rank : 126)
Query Neighborhood Hits	140	Target Neighborhood Hits	1430	Shared Neighborhood Hits	105
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CCHCR_MOUSE
NC score	0.062183 (rank : 102)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	140	Target Neighborhood Hits	932	Shared Neighborhood Hits	95
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

FYCO1_MOUSE
NC score	0.062178 (rank : 103)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	140	Target Neighborhood Hits	1059	Shared Neighborhood Hits	102
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

CNTRB_MOUSE
NC score	0.062152 (rank : 104)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	140	Target Neighborhood Hits	1029	Shared Neighborhood Hits	92
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

BRE1B_MOUSE
NC score	0.062072 (rank : 105)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	140	Target Neighborhood Hits	970	Shared Neighborhood Hits	88
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

KTN1_MOUSE
NC score	0.061977 (rank : 106)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	140	Target Neighborhood Hits	1324	Shared Neighborhood Hits	98
SwissProt Accessions	Q61595, Q8BG49, Q8BHF4, Q8BHM8, Q8C9Y5, Q8CG51, Q8CG52, Q8CG53, Q8CG54, Q8CG55, Q8CG56, Q8CG57, Q8CG58, Q8CG59, Q8CG60, Q8CG61, Q8CG62, Q8CG63	Gene names	Ktn1
Domain Architecture	No domain graphic available
Description	Kinectin.

PLEC1_HUMAN
NC score	0.061951 (rank : 107)	θ value	0.365318 (rank : 47)
Query Neighborhood Hits	140	Target Neighborhood Hits	1326	Shared Neighborhood Hits	100
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

RIMB1_HUMAN
NC score	0.061898 (rank : 108)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	140	Target Neighborhood Hits	1479	Shared Neighborhood Hits	92
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

CYLN2_HUMAN
NC score	0.061855 (rank : 109)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	140	Target Neighborhood Hits	1004	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

CE152_HUMAN
NC score	0.061483 (rank : 110)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	140	Target Neighborhood Hits	976	Shared Neighborhood Hits	91
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CEP63_HUMAN
NC score	0.061480 (rank : 111)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	140	Target Neighborhood Hits	1005	Shared Neighborhood Hits	95
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

SH22A_MOUSE
NC score	0.061467 (rank : 112)	θ value	8.99809 (rank : 135)
Query Neighborhood Hits	140	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

ANR26_HUMAN
NC score	0.061437 (rank : 113)	θ value	1.38821 (rank : 65)
Query Neighborhood Hits	140	Target Neighborhood Hits	1614	Shared Neighborhood Hits	106
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

GOGA5_MOUSE
NC score	0.061433 (rank : 114)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	140	Target Neighborhood Hits	1434	Shared Neighborhood Hits	100
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

DESP_HUMAN
NC score	0.061393 (rank : 115)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	140	Target Neighborhood Hits	1470	Shared Neighborhood Hits	106
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

GOGA3_HUMAN
NC score	0.061157 (rank : 116)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	140	Target Neighborhood Hits	1317	Shared Neighborhood Hits	99
SwissProt Accessions	Q08378, O43241, Q6P9C7, Q86XW3, Q8TDA9, Q8WZA3	Gene names	GOLGA3
Domain Architecture
Description	Golgin subfamily A member 3 (Golgin-160) (Golgi complex-associated protein of 170 kDa) (GCP170).

P85A_HUMAN
NC score	0.060995 (rank : 117)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	140	Target Neighborhood Hits	479	Shared Neighborhood Hits	64
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

MACF1_HUMAN
NC score	0.060970 (rank : 118)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	140	Target Neighborhood Hits	1341	Shared Neighborhood Hits	104
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

GRAP1_HUMAN
NC score	0.060828 (rank : 119)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	140	Target Neighborhood Hits	944	Shared Neighborhood Hits	92
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

AZI1_MOUSE
NC score	0.060743 (rank : 120)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	140	Target Neighborhood Hits	990	Shared Neighborhood Hits	93
SwissProt Accessions	Q62036	Gene names	Azi1, Az1, Azi
Domain Architecture
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1).

CCD21_MOUSE
NC score	0.060371 (rank : 121)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	140	Target Neighborhood Hits	1135	Shared Neighborhood Hits	95
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CJ118_MOUSE
NC score	0.060297 (rank : 122)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	140	Target Neighborhood Hits	1132	Shared Neighborhood Hits	94
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

SAS6_MOUSE
NC score	0.060278 (rank : 123)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	140	Target Neighborhood Hits	931	Shared Neighborhood Hits	96
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

MD1L1_MOUSE
NC score	0.060161 (rank : 124)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	140	Target Neighborhood Hits	1001	Shared Neighborhood Hits	96
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

CKAP4_MOUSE
NC score	0.060087 (rank : 125)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	140	Target Neighborhood Hits	596	Shared Neighborhood Hits	83
SwissProt Accessions	Q8BMK4, Q8BTK8, Q8R3F2	Gene names	Ckap4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

CCD91_HUMAN
NC score	0.059985 (rank : 126)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	140	Target Neighborhood Hits	868	Shared Neighborhood Hits	85
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

SYNE1_HUMAN
NC score	0.059683 (rank : 127)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	140	Target Neighborhood Hits	1484	Shared Neighborhood Hits	98
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

EVPL_MOUSE
NC score	0.059454 (rank : 128)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	140	Target Neighborhood Hits	952	Shared Neighborhood Hits	96
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

P85A_MOUSE
NC score	0.059263 (rank : 129)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	140	Target Neighborhood Hits	435	Shared Neighborhood Hits	57
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

CR034_HUMAN
NC score	0.059154 (rank : 130)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	140	Target Neighborhood Hits	538	Shared Neighborhood Hits	75
SwissProt Accessions	Q5BJE1, Q6ZP67, Q6ZU20	Gene names	C18orf34
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34.

SDCG8_HUMAN
NC score	0.059137 (rank : 131)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	140	Target Neighborhood Hits	1002	Shared Neighborhood Hits	90
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

FLIP1_HUMAN
NC score	0.059073 (rank : 132)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	140	Target Neighborhood Hits	1405	Shared Neighborhood Hits	96
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

CCD13_HUMAN
NC score	0.058565 (rank : 133)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	140	Target Neighborhood Hits	721	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

ANR26_MOUSE
NC score	0.058563 (rank : 134)	θ value	0.47712 (rank : 48)
Query Neighborhood Hits	140	Target Neighborhood Hits	1554	Shared Neighborhood Hits	106
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

TMF1_HUMAN
NC score	0.058543 (rank : 135)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	140	Target Neighborhood Hits	987	Shared Neighborhood Hits	84
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

GCC1_HUMAN
NC score	0.058453 (rank : 136)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	140	Target Neighborhood Hits	887	Shared Neighborhood Hits	92
SwissProt Accessions	Q96CN9, Q9H6N7	Gene names	GCC1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

GCC1_MOUSE
NC score	0.058304 (rank : 137)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	140	Target Neighborhood Hits	777	Shared Neighborhood Hits	87
SwissProt Accessions	Q9D4H2, Q8CCR3	Gene names	Gcc1
Domain Architecture	No domain graphic available
Description	GRIP and coiled-coil domain-containing protein 1 (Golgi coiled coil protein 1).

CCD41_MOUSE
NC score	0.058129 (rank : 138)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	140	Target Neighborhood Hits	1399	Shared Neighborhood Hits	102
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

PIBF1_HUMAN
NC score	0.058108 (rank : 139)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	140	Target Neighborhood Hits	1041	Shared Neighborhood Hits	92
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

SWP70_HUMAN
NC score	0.058026 (rank : 140)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	140	Target Neighborhood Hits	973	Shared Neighborhood Hits	90
SwissProt Accessions	Q9UH65, O75135, Q7LCY6, Q9P061, Q9P0Z8	Gene names	SWAP70, KIAA0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

SDCG8_MOUSE
NC score	0.057943 (rank : 141)	θ value	8.99809 (rank : 134)
Query Neighborhood Hits	140	Target Neighborhood Hits	886	Shared Neighborhood Hits	85
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

EP15R_MOUSE
NC score	0.057710 (rank : 142)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	140	Target Neighborhood Hits	1135	Shared Neighborhood Hits	105
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

CCD46_MOUSE
NC score	0.057692 (rank : 143)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	140	Target Neighborhood Hits	1405	Shared Neighborhood Hits	101
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

C102B_HUMAN
NC score	0.057644 (rank : 144)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	140	Target Neighborhood Hits	542	Shared Neighborhood Hits	76
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

PEPL_HUMAN
NC score	0.057596 (rank : 145)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	140	Target Neighborhood Hits	1141	Shared Neighborhood Hits	91
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

MD1L1_HUMAN
NC score	0.057570 (rank : 146)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	140	Target Neighborhood Hits	893	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

HOOK2_HUMAN
NC score	0.057564 (rank : 147)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	140	Target Neighborhood Hits	714	Shared Neighborhood Hits	92
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

AZI1_HUMAN
NC score	0.057489 (rank : 148)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	140	Target Neighborhood Hits	1000	Shared Neighborhood Hits	91
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

FLIP1_MOUSE
NC score	0.057433 (rank : 149)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	140	Target Neighborhood Hits	1176	Shared Neighborhood Hits	96
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

KMHN1_HUMAN
NC score	0.057356 (rank : 150)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	140	Target Neighborhood Hits	950	Shared Neighborhood Hits	90
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

EP15R_HUMAN
NC score	0.057304 (rank : 151)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	140	Target Neighborhood Hits	1083	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

LZTS1_HUMAN
NC score	0.057296 (rank : 152)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	140	Target Neighborhood Hits	532	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y250, Q9Y5V7, Q9Y5V8, Q9Y5V9, Q9Y5W0, Q9Y5W1, Q9Y5W2	Gene names	LZTS1, FEZ1
Domain Architecture
Description	Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

PEPL_MOUSE
NC score	0.057221 (rank : 153)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	140	Target Neighborhood Hits	1105	Shared Neighborhood Hits	90
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

GOGA5_HUMAN
NC score	0.056848 (rank : 154)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	140	Target Neighborhood Hits	1168	Shared Neighborhood Hits	98
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

NEMO_HUMAN
NC score	0.056838 (rank : 155)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	140	Target Neighborhood Hits	820	Shared Neighborhood Hits	92
SwissProt Accessions	Q9Y6K9	Gene names	IKBKG, FIP3, NEMO
Domain Architecture	No domain graphic available
Description	NF-kappa-B essential modulator (NEMO) (NF-kappa-B essential modifier) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (IkB kinase subunit gamma) (I-kappa-B kinase gamma) (IKK-gamma) (IKKG) (IkB kinase-associated protein 1) (IKKAP1) (FIP-3).

CCD96_MOUSE
NC score	0.056781 (rank : 156)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	140	Target Neighborhood Hits	704	Shared Neighborhood Hits	80
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

LRC45_HUMAN
NC score	0.056760 (rank : 157)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	140	Target Neighborhood Hits	933	Shared Neighborhood Hits	94
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

SPAG5_MOUSE
NC score	0.056716 (rank : 158)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	140	Target Neighborhood Hits	612	Shared Neighborhood Hits	81
SwissProt Accessions	Q7TME2, Q8CH61	Gene names	Spag5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126).

CEP70_MOUSE
NC score	0.056690 (rank : 159)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	140	Target Neighborhood Hits	532	Shared Neighborhood Hits	85
SwissProt Accessions	Q6IQY5, Q9CRL9, Q9CTS4, Q9JIC1	Gene names	Cep70
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 70 kDa (Cep70 protein).

HOOK1_HUMAN
NC score	0.056650 (rank : 160)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	140	Target Neighborhood Hits	942	Shared Neighborhood Hits	88
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

CCDC6_HUMAN
NC score	0.056634 (rank : 161)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	140	Target Neighborhood Hits	723	Shared Neighborhood Hits	79
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

LZTS1_MOUSE
NC score	0.056611 (rank : 162)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	140	Target Neighborhood Hits	540	Shared Neighborhood Hits	79
SwissProt Accessions	P60853	Gene names	Lzts1, Fez1
Domain Architecture	No domain graphic available
Description	Leucine zipper putative tumor suppressor 1 (F37/Esophageal cancer- related gene-coding leucine-zipper motif) (Fez1).

MY18A_HUMAN
NC score	0.056598 (rank : 163)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	140	Target Neighborhood Hits	1929	Shared Neighborhood Hits	111
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

K0555_HUMAN
NC score	0.056554 (rank : 164)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	140	Target Neighborhood Hits	880	Shared Neighborhood Hits	89
SwissProt Accessions	Q96AA8, O60302	Gene names	KIAA0555
Domain Architecture	No domain graphic available
Description	Protein KIAA0555.

RB6I2_HUMAN
NC score	0.056402 (rank : 165)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	140	Target Neighborhood Hits	1584	Shared Neighborhood Hits	100
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

APOE_MOUSE
NC score	0.056331 (rank : 166)	θ value	8.99809 (rank : 124)
Query Neighborhood Hits	140	Target Neighborhood Hits	319	Shared Neighborhood Hits	61
SwissProt Accessions	P08226	Gene names	Apoe
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

CN145_HUMAN
NC score	0.056268 (rank : 167)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	140	Target Neighborhood Hits	1196	Shared Neighborhood Hits	98
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

RUFY1_HUMAN
NC score	0.056042 (rank : 168)	θ value	0.813845 (rank : 60)
Query Neighborhood Hits	140	Target Neighborhood Hits	848	Shared Neighborhood Hits	94
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

CCD11_MOUSE
NC score	0.055987 (rank : 169)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	140	Target Neighborhood Hits	498	Shared Neighborhood Hits	76
SwissProt Accessions	Q9D439	Gene names	Ccdc11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

ERC2_MOUSE
NC score	0.055938 (rank : 170)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	140	Target Neighborhood Hits	1166	Shared Neighborhood Hits	96
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

HOOK1_MOUSE
NC score	0.055919 (rank : 171)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	140	Target Neighborhood Hits	910	Shared Neighborhood Hits	90
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

CN145_MOUSE
NC score	0.055848 (rank : 172)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	140	Target Neighborhood Hits	916	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

CK5P2_MOUSE
NC score	0.055818 (rank : 173)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	140	Target Neighborhood Hits	1151	Shared Neighborhood Hits	94
SwissProt Accessions	Q8K389, Q6PCN1, Q6ZPL0	Gene names	Cdk5rap2, Kiaa1633
Domain Architecture	No domain graphic available
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48).

CCD91_MOUSE
NC score	0.055756 (rank : 174)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	140	Target Neighborhood Hits	699	Shared Neighborhood Hits	82
SwissProt Accessions	Q9D8L5, Q8R3N8, Q9D9E8	Gene names	Ccdc91, Ggabp
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner).

ERC2_HUMAN
NC score	0.055735 (rank : 175)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	140	Target Neighborhood Hits	1156	Shared Neighborhood Hits	95
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

MPP9_HUMAN
NC score	0.055708 (rank : 176)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	140	Target Neighborhood Hits	529	Shared Neighborhood Hits	69
SwissProt Accessions	Q99550, Q9H976	Gene names	MPHOSPH9, MPP9
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 9.

KNTC2_MOUSE
NC score	0.055643 (rank : 177)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	140	Target Neighborhood Hits	692	Shared Neighborhood Hits	79
SwissProt Accessions	Q9D0F1, Q3TQT6, Q3UWM5, Q99P70	Gene names	Kntc2, Hec1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (Kinetochore-associated protein 2).

RBCC1_HUMAN
NC score	0.055605 (rank : 178)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	140	Target Neighborhood Hits	1023	Shared Neighborhood Hits	93
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

RUFY2_HUMAN
NC score	0.055541 (rank : 179)	θ value	8.99809 (rank : 133)
Query Neighborhood Hits	140	Target Neighborhood Hits	1208	Shared Neighborhood Hits	97
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

CCD41_HUMAN
NC score	0.055524 (rank : 180)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	140	Target Neighborhood Hits	1139	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y592	Gene names	CCDC41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41 (NY-REN-58 antigen).

CI039_HUMAN
NC score	0.055520 (rank : 181)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	140	Target Neighborhood Hits	1171	Shared Neighborhood Hits	96
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

ADIP_HUMAN
NC score	0.055508 (rank : 182)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	140	Target Neighborhood Hits	470	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y2D8, Q6P2P8, Q6ULS1, Q7L168, Q9UIX0	Gene names	SSX2IP, KIAA0923
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein) (SSX2-interacting protein).

EVPL_HUMAN
NC score	0.055419 (rank : 183)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	140	Target Neighborhood Hits	895	Shared Neighborhood Hits	93
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

BRE1B_HUMAN
NC score	0.055404 (rank : 184)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	140	Target Neighborhood Hits	1040	Shared Neighborhood Hits	86
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

OPTN_HUMAN
NC score	0.055298 (rank : 185)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	140	Target Neighborhood Hits	827	Shared Neighborhood Hits	83
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

XE7_HUMAN
NC score	0.055271 (rank : 186)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	140	Target Neighborhood Hits	738	Shared Neighborhood Hits	85
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

KMHN1_MOUSE
NC score	0.055243 (rank : 187)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	140	Target Neighborhood Hits	949	Shared Neighborhood Hits	86
SwissProt Accessions	Q3V125, Q3TTQ8	Gene names	Gm172
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1 homolog.

CASP_HUMAN
NC score	0.055228 (rank : 188)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	140	Target Neighborhood Hits	1131	Shared Neighborhood Hits	93
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

OPTN_MOUSE
NC score	0.055139 (rank : 189)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	140	Target Neighborhood Hits	1120	Shared Neighborhood Hits	91
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

GOG8A_HUMAN
NC score	0.055127 (rank : 190)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	140	Target Neighborhood Hits	635	Shared Neighborhood Hits	86
SwissProt Accessions	Q9NZW0, O94937, Q9NZG8, Q9NZW3	Gene names	GOLGA8A, KIAA0855
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 8A/B (Golgi autoantigen golgin-67) (88 kDa Golgi protein) (Gm88 autoantigen).

RB6I2_MOUSE
NC score	0.055059 (rank : 191)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	140	Target Neighborhood Hits	1433	Shared Neighborhood Hits	98
SwissProt Accessions	Q99MI1, Q80TK7, Q8BPL1, Q8C7Y1, Q99MI2	Gene names	Erc1, Cast2, Kiaa1081, Rab6ip2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1) (ERC1) (CAZ-associated structural protein 2) (CAST2).

KNTC2_HUMAN
NC score	0.054930 (rank : 192)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	140	Target Neighborhood Hits	673	Shared Neighborhood Hits	80
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

GAS8_MOUSE
NC score	0.054765 (rank : 193)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	140	Target Neighborhood Hits	622	Shared Neighborhood Hits	84
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

HOOK2_MOUSE
NC score	0.054711 (rank : 194)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	140	Target Neighborhood Hits	736	Shared Neighborhood Hits	91
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

CALD1_HUMAN
NC score	0.054704 (rank : 195)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	140	Target Neighborhood Hits	959	Shared Neighborhood Hits	86
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

IFT81_MOUSE
NC score	0.054630 (rank : 196)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	140	Target Neighborhood Hits	959	Shared Neighborhood Hits	88
SwissProt Accessions	O35594, Q8R4W2, Q9CSA1, Q9EQM1	Gene names	Ift81, Cdv-1, Cdv1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

SAS6_HUMAN
NC score	0.054517 (rank : 197)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	140	Target Neighborhood Hits	791	Shared Neighborhood Hits	86
SwissProt Accessions	Q6UVJ0, Q8N3K0	Gene names	SASS6, SAS6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog (HsSAS-6).

SYCP1_HUMAN
NC score	0.054494 (rank : 198)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	140	Target Neighborhood Hits	1313	Shared Neighborhood Hits	93
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TUFT1_MOUSE
NC score	0.054277 (rank : 199)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	140	Target Neighborhood Hits	732	Shared Neighborhood Hits	82
SwissProt Accessions	O08970	Gene names	Tuft1
Domain Architecture
Description	Tuftelin.

MY18A_MOUSE
NC score	0.054228 (rank : 200)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	140	Target Neighborhood Hits	1989	Shared Neighborhood Hits	113
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CEP55_HUMAN
NC score	0.054045 (rank : 201)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	140	Target Neighborhood Hits	504	Shared Neighborhood Hits	73
SwissProt Accessions	Q53EZ4, Q32WF5, Q3MV20, Q5VY28, Q6N034, Q96H32, Q9NVS7	Gene names	CEP55, C10orf3, URCC6
Domain Architecture	No domain graphic available
Description	Centrosome protein 55 (Up-regulated in colon cancer 6).

TSC1_HUMAN
NC score	0.053986 (rank : 202)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	140	Target Neighborhood Hits	765	Shared Neighborhood Hits	89
SwissProt Accessions	Q92574	Gene names	TSC1, KIAA0243, TSC
Domain Architecture
Description	Hamartin (Tuberous sclerosis 1 protein).

PININ_HUMAN
NC score	0.053759 (rank : 203)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	140	Target Neighborhood Hits	753	Shared Neighborhood Hits	77
SwissProt Accessions	Q9H307, O60899, Q53EM7, Q6P5X4, Q7KYL1, Q99738, Q9UHZ9, Q9UQR9	Gene names	PNN, DRS, MEMA
Domain Architecture	No domain graphic available
Description	Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Domain-rich serine protein) (DRS-protein) (DRSP) (Melanoma metastasis clone A protein) (Desmosome-associated protein) (SR-like protein) (Nuclear protein SDK3).

CYTSA_MOUSE
NC score	0.053650 (rank : 204)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	140	Target Neighborhood Hits	1104	Shared Neighborhood Hits	95
SwissProt Accessions	Q2KN98, Q8CHF9	Gene names	Cytsa, Kiaa0376
Domain Architecture	No domain graphic available
Description	Cytospin-A.

DMD_MOUSE
NC score	0.053582 (rank : 205)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	140	Target Neighborhood Hits	1111	Shared Neighborhood Hits	92
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

SYCP1_MOUSE
NC score	0.053541 (rank : 206)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	140	Target Neighborhood Hits	1456	Shared Neighborhood Hits	94
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

RRBP1_HUMAN
NC score	0.053421 (rank : 207)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	140	Target Neighborhood Hits	1306	Shared Neighborhood Hits	97
SwissProt Accessions	Q9P2E9, O75300, O75301, Q5W165, Q96SB2, Q9BWP1, Q9H476	Gene names	RRBP1, KIAA1398
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (180 kDa ribosome receptor homolog) (ES/130-related protein).

DYNA_HUMAN
NC score	0.053412 (rank : 208)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	140	Target Neighborhood Hits	1194	Shared Neighborhood Hits	92
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

IFT81_HUMAN
NC score	0.053399 (rank : 209)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	140	Target Neighborhood Hits	893	Shared Neighborhood Hits	89
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

UACA_MOUSE
NC score	0.053378 (rank : 210)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	140	Target Neighborhood Hits	1620	Shared Neighborhood Hits	99
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

MIPO1_HUMAN
NC score	0.053233 (rank : 211)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	140	Target Neighborhood Hits	486	Shared Neighborhood Hits	75
SwissProt Accessions	Q8TD10, Q7Z3J0, Q8IV14	Gene names	MIPOL1
Domain Architecture	No domain graphic available
Description	Mirror-image polydactyly gene 1 protein.

SMC3_MOUSE
NC score	0.053213 (rank : 212)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	140	Target Neighborhood Hits	1187	Shared Neighborhood Hits	100
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

GAS8_HUMAN
NC score	0.053153 (rank : 213)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	140	Target Neighborhood Hits	819	Shared Neighborhood Hits	87
SwissProt Accessions	O95995	Gene names	GAS8, GAS11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

RABE2_HUMAN
NC score	0.053147 (rank : 214)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	140	Target Neighborhood Hits	545	Shared Neighborhood Hits	79
SwissProt Accessions	Q9H5N1	Gene names	RABEP2, RABPT5B
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

SPAG5_HUMAN
NC score	0.053144 (rank : 215)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	140	Target Neighborhood Hits	625	Shared Neighborhood Hits	83
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

CK5P2_HUMAN
NC score	0.053114 (rank : 216)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	140	Target Neighborhood Hits	1433	Shared Neighborhood Hits	99
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

TNIP3_HUMAN
NC score	0.053092 (rank : 217)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	140	Target Neighborhood Hits	511	Shared Neighborhood Hits	76
SwissProt Accessions	Q96KP6, Q96PQ3, Q9H780	Gene names	TNIP3, ABIN3, LIND
Domain Architecture	No domain graphic available
Description	TNFAIP3-interacting protein 3 (Listeria-induced gene protein) (A20- binding inhibitor of NF-kappa-B activation 3) (ABIN-3).

SMC3_HUMAN
NC score	0.053022 (rank : 218)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	140	Target Neighborhood Hits	1186	Shared Neighborhood Hits	100
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

CYTSA_HUMAN
NC score	0.052907 (rank : 219)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	140	Target Neighborhood Hits	1138	Shared Neighborhood Hits	97
SwissProt Accessions	Q69YQ0, O15081	Gene names	CYTSA, KIAA0376
Domain Architecture	No domain graphic available
Description	Cytospin-A (NY-REN-22 antigen).

DYNA_MOUSE
NC score	0.052877 (rank : 220)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	140	Target Neighborhood Hits	1084	Shared Neighborhood Hits	90
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

TAXB1_HUMAN
NC score	0.052729 (rank : 221)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	140	Target Neighborhood Hits	829	Shared Neighborhood Hits	85
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

VDP_HUMAN
NC score	0.052699 (rank : 222)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	140	Target Neighborhood Hits	645	Shared Neighborhood Hits	79
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

MACF1_MOUSE
NC score	0.052694 (rank : 223)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	140	Target Neighborhood Hits	1313	Shared Neighborhood Hits	96
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

KCT2_MOUSE
NC score	0.052637 (rank : 224)	θ value	0.0736092 (rank : 23)
Query Neighborhood Hits	140	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K201, Q5SVC5, Q922L7, Q9CVN1	Gene names	Kct2
Domain Architecture	No domain graphic available
Description	Keratinocytes-associated transmembrane protein 2 precursor.

RUFY2_MOUSE
NC score	0.052542 (rank : 225)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	140	Target Neighborhood Hits	820	Shared Neighborhood Hits	89
SwissProt Accessions	Q8R4C2, Q69ZH1	Gene names	Rufy2, Kiaa1537
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Leucine zipper FYVE-finger protein) (LZ-FYVE).

ZN291_HUMAN
NC score	0.052492 (rank : 226)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	140	Target Neighborhood Hits	647	Shared Neighborhood Hits	79
SwissProt Accessions	Q9BY12	Gene names	ZNF291
Domain Architecture
Description	Zinc finger protein 291.

EP15_HUMAN
NC score	0.052485 (rank : 227)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	140	Target Neighborhood Hits	1021	Shared Neighborhood Hits	102
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

CKAP4_HUMAN
NC score	0.052483 (rank : 228)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	140	Target Neighborhood Hits	592	Shared Neighborhood Hits	74
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

LUZP1_HUMAN
NC score	0.052423 (rank : 229)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	140	Target Neighborhood Hits	739	Shared Neighborhood Hits	86
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

CASP_MOUSE
NC score	0.052398 (rank : 230)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	140	Target Neighborhood Hits	1152	Shared Neighborhood Hits	92
SwissProt Accessions	P70403, Q7TQJ4, Q91WN6	Gene names	Cutl1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CEP55_MOUSE
NC score	0.052393 (rank : 231)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	140	Target Neighborhood Hits	693	Shared Neighborhood Hits	81
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

BICD1_HUMAN
NC score	0.052319 (rank : 232)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	140	Target Neighborhood Hits	844	Shared Neighborhood Hits	91
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

ADIP_MOUSE
NC score	0.052301 (rank : 233)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	140	Target Neighborhood Hits	415	Shared Neighborhood Hits	75
SwissProt Accessions	Q8VC66, Q8BG59, Q8C7X0, Q8K2F7	Gene names	Ssx2ip
Domain Architecture	No domain graphic available
Description	Afadin- and alpha-actinin-binding protein (ADIP) (Afadin DIL domain- interacting protein).

BPAEA_HUMAN
NC score	0.052300 (rank : 234)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	140	Target Neighborhood Hits	1369	Shared Neighborhood Hits	92
SwissProt Accessions	O94833, Q5TBT0, Q8N1T8, Q8N8J3, Q8WXK9, Q96AK9, Q96DQ5, Q9H555	Gene names	DST, BPAG1, DMH, DT, KIAA0728
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 6/9/10 (Trabeculin-beta) (Bullous pemphigoid antigen) (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

RBCC1_MOUSE
NC score	0.052245 (rank : 235)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	140	Target Neighborhood Hits	1048	Shared Neighborhood Hits	90
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

RUFY1_MOUSE
NC score	0.052238 (rank : 236)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	140	Target Neighborhood Hits	765	Shared Neighborhood Hits	86
SwissProt Accessions	Q8BIJ7, Q8BKQ4, Q8BL21, Q9EPM6	Gene names	Rufy1, Rabip4
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 1 (Rab4-interacting protein).

K0552_HUMAN
NC score	0.052207 (rank : 237)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	140	Target Neighborhood Hits	442	Shared Neighborhood Hits	74
SwissProt Accessions	O60299	Gene names	KIAA0552
Domain Architecture
Description	Protein KIAA0552.

CJ118_HUMAN
NC score	0.052081 (rank : 238)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	140	Target Neighborhood Hits	937	Shared Neighborhood Hits	87
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

BPA1_MOUSE
NC score	0.052047 (rank : 239)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	140	Target Neighborhood Hits	1477	Shared Neighborhood Hits	98
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

LIPA1_HUMAN
NC score	0.052020 (rank : 240)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	140	Target Neighborhood Hits	1294	Shared Neighborhood Hits	92
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

PININ_MOUSE
NC score	0.052015 (rank : 241)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	140	Target Neighborhood Hits	777	Shared Neighborhood Hits	73
SwissProt Accessions	O35691, Q8CD89, Q8CGU3	Gene names	Pnn
Domain Architecture	No domain graphic available
Description	Pinin.

LUZP1_MOUSE
NC score	0.051951 (rank : 242)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	140	Target Neighborhood Hits	940	Shared Neighborhood Hits	79
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

CARD9_HUMAN
NC score	0.051894 (rank : 243)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	140	Target Neighborhood Hits	602	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H257, Q5SXM6, Q9H854	Gene names	CARD9
Domain Architecture
Description	Caspase recruitment domain-containing protein 9 (hCARD9).

CR034_MOUSE
NC score	0.051877 (rank : 244)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	140	Target Neighborhood Hits	643	Shared Neighborhood Hits	75
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

INCE_MOUSE
NC score	0.051814 (rank : 245)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	140	Target Neighborhood Hits	903	Shared Neighborhood Hits	89
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

BICD1_MOUSE
NC score	0.051666 (rank : 246)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	140	Target Neighborhood Hits	837	Shared Neighborhood Hits	89
SwissProt Accessions	Q8BR07, O55206, Q8BQ18, Q8BRR8, Q8C4D3, Q8CAK6, Q8R2J4, Q8R2J5, Q8R2J6, Q91YP7	Gene names	Bicd1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

APOA4_MOUSE
NC score	0.051635 (rank : 247)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	140	Target Neighborhood Hits	435	Shared Neighborhood Hits	63
SwissProt Accessions	P06728	Gene names	Apoa4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

OFD1_HUMAN
NC score	0.051604 (rank : 248)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	140	Target Neighborhood Hits	753	Shared Neighborhood Hits	81
SwissProt Accessions	O75665, O75666	Gene names	OFD1, CXorf5
Domain Architecture	No domain graphic available
Description	Oral-facial-digital syndrome 1 protein (Protein 71-7A).

LRC45_MOUSE
NC score	0.051481 (rank : 249)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	140	Target Neighborhood Hits	959	Shared Neighborhood Hits	86
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

CCD62_HUMAN
NC score	0.051460 (rank : 250)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	140	Target Neighborhood Hits	631	Shared Neighborhood Hits	77
SwissProt Accessions	Q6P9F0, Q6ZVF2, Q86VJ0, Q9BYZ5	Gene names	CCDC62
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60 (Aaa-protein) (Protein TSP- NY).

BICD2_MOUSE
NC score	0.051406 (rank : 251)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	140	Target Neighborhood Hits	864	Shared Neighborhood Hits	88
SwissProt Accessions	Q921C5, Q80TU1, Q8BTE3, Q9DCL3	Gene names	Bicd2, Kiaa0699
Domain Architecture
Description	Cytoskeleton-like bicaudal D protein homolog 2.

T3JAM_HUMAN
NC score	0.051146 (rank : 252)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	140	Target Neighborhood Hits	533	Shared Neighborhood Hits	78
SwissProt Accessions	Q9Y228, Q2YDB5, Q4VY06, Q7Z706	Gene names	TRAF3IP3, T3JAM
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

HAP1_HUMAN
NC score	0.051119 (rank : 253)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	140	Target Neighborhood Hits	606	Shared Neighborhood Hits	87
SwissProt Accessions	P54257, O75358, Q9H4G3, Q9HA98, Q9NY90	Gene names	HAP1, HLP1
Domain Architecture
Description	Huntingtin-associated protein 1 (HAP-1) (Neuroan 1).

TAXB1_MOUSE
NC score	0.051050 (rank : 254)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	140	Target Neighborhood Hits	886	Shared Neighborhood Hits	85
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

SMC2_HUMAN
NC score	0.050843 (rank : 255)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	140	Target Neighborhood Hits	1405	Shared Neighborhood Hits	102
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

HOOK3_HUMAN
NC score	0.050745 (rank : 256)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	140	Target Neighborhood Hits	1070	Shared Neighborhood Hits	94
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

HAPIP_HUMAN
NC score	0.050726 (rank : 257)	θ value	0.47712 (rank : 50)
Query Neighborhood Hits	140	Target Neighborhood Hits	350	Shared Neighborhood Hits	53
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

DMD_HUMAN
NC score	0.050640 (rank : 258)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	140	Target Neighborhood Hits	1135	Shared Neighborhood Hits	92
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

CA065_HUMAN
NC score	0.050625 (rank : 259)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	140	Target Neighborhood Hits	469	Shared Neighborhood Hits	69
SwissProt Accessions	Q8N715, Q8N746, Q8NA93	Gene names	C1orf65
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C1orf65.

TEX9_MOUSE
NC score	0.050616 (rank : 260)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	140	Target Neighborhood Hits	581	Shared Neighborhood Hits	81
SwissProt Accessions	Q9D845, O54764	Gene names	Tex9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein (Testis-specifically expressed protein 1) (Tsec-1).

SYNE2_HUMAN
NC score	0.050551 (rank : 261)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	140	Target Neighborhood Hits	1323	Shared Neighborhood Hits	95
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

CEP57_MOUSE
NC score	0.050491 (rank : 262)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	140	Target Neighborhood Hits	580	Shared Neighborhood Hits	74
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

UACA_HUMAN
NC score	0.050469 (rank : 263)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	140	Target Neighborhood Hits	1622	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

INVO_MOUSE
NC score	0.050374 (rank : 264)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	140	Target Neighborhood Hits	474	Shared Neighborhood Hits	69
SwissProt Accessions	P48997	Gene names	Ivl
Domain Architecture	No domain graphic available
Description	Involucrin.

BSN_HUMAN
NC score	0.050307 (rank : 265)	θ value	0.163984 (rank : 33)
Query Neighborhood Hits	140	Target Neighborhood Hits	1537	Shared Neighborhood Hits	73
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

LRRF2_HUMAN
NC score	0.050122 (rank : 266)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	140	Target Neighborhood Hits	791	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y608, Q68CV3, Q9NXH5	Gene names	LRRFIP2
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat flightless-interacting protein 2 (LRR FLII- interacting protein 2).

MED12_HUMAN
NC score	0.048427 (rank : 267)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	140	Target Neighborhood Hits	262	Shared Neighborhood Hits	43
SwissProt Accessions	Q93074, O15410, O75557, Q9UHV6, Q9UND7	Gene names	MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230
Domain Architecture	No domain graphic available
Description	Mediator of RNA polymerase II transcription subunit 12 (Thyroid hormone receptor-associated protein complex 230 kDa component) (Trap230) (Activator-recruited cofactor 240 kDa component) (ARC240) (CAG repeat protein 45) (OPA-containing protein) (Trinucleotide repeat-containing gene 11 protein).

K1683_HUMAN
NC score	0.048275 (rank : 268)	θ value	0.813845 (rank : 57)
Query Neighborhood Hits	140	Target Neighborhood Hits	240	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

MLL2_HUMAN
NC score	0.047100 (rank : 269)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	140	Target Neighborhood Hits	1788	Shared Neighborhood Hits	74
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

CLC4F_HUMAN
NC score	0.047029 (rank : 270)	θ value	5.27518 (rank : 101)
Query Neighborhood Hits	140	Target Neighborhood Hits	513	Shared Neighborhood Hits	68
SwissProt Accessions	Q8N1N0	Gene names	CLEC4F, CLECSF13
Domain Architecture	No domain graphic available
Description	C-type lectin domain family 4 member F (C-type lectin superfamily member 13) (C-type lectin 13).

DIDO1_HUMAN
NC score	0.046660 (rank : 271)	θ value	0.163984 (rank : 34)
Query Neighborhood Hits	140	Target Neighborhood Hits	960	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

CTRO_MOUSE
NC score	0.046377 (rank : 272)	θ value	0.21417 (rank : 40)
Query Neighborhood Hits	140	Target Neighborhood Hits	2344	Shared Neighborhood Hits	110
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

SPTB2_HUMAN
NC score	0.046267 (rank : 273)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	140	Target Neighborhood Hits	748	Shared Neighborhood Hits	86
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTA1_HUMAN
NC score	0.046252 (rank : 274)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	140	Target Neighborhood Hits	748	Shared Neighborhood Hits	81
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

MYH13_HUMAN
NC score	0.046124 (rank : 275)	θ value	8.99809 (rank : 131)
Query Neighborhood Hits	140	Target Neighborhood Hits	1504	Shared Neighborhood Hits	101
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH6_HUMAN
NC score	0.046114 (rank : 276)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	140	Target Neighborhood Hits	1426	Shared Neighborhood Hits	94
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

CTRO_HUMAN
NC score	0.045757 (rank : 277)	θ value	0.0563607 (rank : 20)
Query Neighborhood Hits	140	Target Neighborhood Hits	2092	Shared Neighborhood Hits	108
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

MYH7_HUMAN
NC score	0.045471 (rank : 278)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	140	Target Neighborhood Hits	1559	Shared Neighborhood Hits	99
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

BSN_MOUSE
NC score	0.042890 (rank : 279)	θ value	0.0961366 (rank : 25)
Query Neighborhood Hits	140	Target Neighborhood Hits	2057	Shared Neighborhood Hits	72
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

KIF5A_HUMAN
NC score	0.041660 (rank : 280)	θ value	1.06291 (rank : 62)
Query Neighborhood Hits	140	Target Neighborhood Hits	843	Shared Neighborhood Hits	86
SwissProt Accessions	Q12840, Q4LE26	Gene names	KIF5A, NKHC1
Domain Architecture
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

KIF5A_MOUSE
NC score	0.041334 (rank : 281)	θ value	1.06291 (rank : 63)
Query Neighborhood Hits	140	Target Neighborhood Hits	859	Shared Neighborhood Hits	83
SwissProt Accessions	P33175, Q5DTP1, Q6PDY7, Q9Z2F9	Gene names	Kif5a, Kiaa4086, Kif5, Nkhc1
Domain Architecture	No domain graphic available
Description	Kinesin heavy chain isoform 5A (Neuronal kinesin heavy chain) (NKHC) (Kinesin heavy chain neuron-specific 1).

SOCS4_MOUSE
NC score	0.039480 (rank : 282)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	140	Target Neighborhood Hits	69	Shared Neighborhood Hits	19
SwissProt Accessions	Q91ZA6	Gene names	Socs4, Socs7
Domain Architecture
Description	Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7).

PCQAP_HUMAN
NC score	0.038955 (rank : 283)	θ value	8.99809 (rank : 132)
Query Neighborhood Hits	140	Target Neighborhood Hits	549	Shared Neighborhood Hits	59
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

FOXP2_MOUSE
NC score	0.038714 (rank : 284)	θ value	1.38821 (rank : 69)
Query Neighborhood Hits	140	Target Neighborhood Hits	366	Shared Neighborhood Hits	57
SwissProt Accessions	P58463, Q6PD37, Q8C4F0, Q8R441	Gene names	Foxp2
Domain Architecture
Description	Forkhead box protein P2.

CD72_MOUSE
NC score	0.037937 (rank : 285)	θ value	5.27518 (rank : 99)
Query Neighborhood Hits	140	Target Neighborhood Hits	262	Shared Neighborhood Hits	48
SwissProt Accessions	P21855, Q64225	Gene names	Cd72, Ly-32, Lyb-2
Domain Architecture
Description	B-cell differentiation antigen CD72 (Lyb-2) (Antigen Ly-32).

FOXP2_HUMAN
NC score	0.037519 (rank : 286)	θ value	1.38821 (rank : 68)
Query Neighborhood Hits	140	Target Neighborhood Hits	366	Shared Neighborhood Hits	57
SwissProt Accessions	O15409, Q6ZND1, Q75MJ3, Q8IZE0, Q8N0W2, Q8N6B7, Q8N6B8, Q8NFQ1, Q8NFQ2, Q8NFQ3, Q8NFQ4, Q8TD74	Gene names	FOXP2, CAGH44, TNRC10
Domain Architecture
Description	Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat- containing gene 10 protein).

SOCS4_HUMAN
NC score	0.037208 (rank : 287)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	140	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXH5	Gene names	SOCS4, SOCS7
Domain Architecture
Description	Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7).

MRCKB_HUMAN
NC score	0.035601 (rank : 288)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	140	Target Neighborhood Hits	2239	Shared Neighborhood Hits	114
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

DYHC_HUMAN
NC score	0.034654 (rank : 289)	θ value	8.99809 (rank : 127)
Query Neighborhood Hits	140	Target Neighborhood Hits	733	Shared Neighborhood Hits	84
SwissProt Accessions	Q14204, Q6DKQ7, Q8WU28, Q92814, Q9Y4G5	Gene names	DYNC1H1, DNCH1, DNECL, KIAA0325
Domain Architecture	No domain graphic available
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

DYHC_MOUSE
NC score	0.034520 (rank : 290)	θ value	8.99809 (rank : 128)
Query Neighborhood Hits	140	Target Neighborhood Hits	729	Shared Neighborhood Hits	83
SwissProt Accessions	Q9JHU4	Gene names	Dync1h1, Dnch1, Dnchc1
Domain Architecture
Description	Dynein heavy chain, cytosolic (DYHC) (Cytoplasmic dynein heavy chain 1) (DHC1) (Dynein heavy chain 1, cytoplasmic 1).

G3BP_HUMAN
NC score	0.033323 (rank : 291)	θ value	1.38821 (rank : 70)
Query Neighborhood Hits	140	Target Neighborhood Hits	219	Shared Neighborhood Hits	10
SwissProt Accessions	Q13283	Gene names	G3BP, G3BP1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

ROCK2_HUMAN
NC score	0.030824 (rank : 292)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	140	Target Neighborhood Hits	2073	Shared Neighborhood Hits	105
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

SPTN4_HUMAN
NC score	0.030692 (rank : 293)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	140	Target Neighborhood Hits	570	Shared Neighborhood Hits	83
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

MRCKG_HUMAN
NC score	0.028461 (rank : 294)	θ value	0.813845 (rank : 58)
Query Neighborhood Hits	140	Target Neighborhood Hits	1519	Shared Neighborhood Hits	96
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

G3BP_MOUSE
NC score	0.027123 (rank : 295)	θ value	1.81305 (rank : 77)
Query Neighborhood Hits	140	Target Neighborhood Hits	209	Shared Neighborhood Hits	7
SwissProt Accessions	P97855	Gene names	G3bp, G3bp1
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 1 (EC 3.6.1.-) (ATP- dependent DNA helicase VIII) (GAP SH3-domain-binding protein 1) (G3BP- 1) (HDH-VIII).

SOCS5_MOUSE
NC score	0.026569 (rank : 296)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	140	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	O54928	Gene names	Socs5, Cish5
Domain Architecture
Description	Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5).

SOCS5_HUMAN
NC score	0.026315 (rank : 297)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	140	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	O75159, Q8IYZ4	Gene names	SOCS5, CIS6, CISH5, CISH6, KIAA0671
Domain Architecture
Description	Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5) (Cytokine-inducible SH2 protein 6) (CIS-6).

MRCKG_MOUSE
NC score	0.023156 (rank : 298)	θ value	0.813845 (rank : 59)
Query Neighborhood Hits	140	Target Neighborhood Hits	1466	Shared Neighborhood Hits	93
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

CHIN_HUMAN
NC score	0.022122 (rank : 299)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	140	Target Neighborhood Hits	227	Shared Neighborhood Hits	19
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

STK10_HUMAN
NC score	0.021975 (rank : 300)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	140	Target Neighborhood Hits	1921	Shared Neighborhood Hits	103
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

BAZ1B_MOUSE
NC score	0.019678 (rank : 301)	θ value	8.99809 (rank : 125)
Query Neighborhood Hits	140	Target Neighborhood Hits	394	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

CHIN_MOUSE
NC score	0.019534 (rank : 302)	θ value	5.27518 (rank : 100)
Query Neighborhood Hits	140	Target Neighborhood Hits	229	Shared Neighborhood Hits	18
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

M4K4_HUMAN
NC score	0.018583 (rank : 303)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	140	Target Neighborhood Hits	1589	Shared Neighborhood Hits	85
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

TIF1B_HUMAN
NC score	0.008122 (rank : 304)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	140	Target Neighborhood Hits	312	Shared Neighborhood Hits	17
SwissProt Accessions	Q13263, O00677, Q7Z632, Q93040, Q96IM1	Gene names	TRIM28, KAP1, RNF96, TIF1B
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (RING finger protein 96).

TIF1B_MOUSE
NC score	0.007682 (rank : 305)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	140	Target Neighborhood Hits	276	Shared Neighborhood Hits	15
SwissProt Accessions	Q62318, P70391, Q8C283, Q99PN4	Gene names	Trim28, Krip1, Tif1b
Domain Architecture
Description	Transcription intermediary factor 1-beta (TIF1-beta) (Tripartite motif-containing protein 28) (KRAB-A-interacting protein) (KRIP-1).

ZP1_HUMAN
NC score	0.006907 (rank : 306)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	140	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	P60852	Gene names	ZP1
Domain Architecture	No domain graphic available
Description	Zona pellucida sperm-binding protein 1 precursor (Zona pellucida glycoprotein 1) (Zp-1).

ERBB3_MOUSE
NC score	0.005183 (rank : 307)	θ value	0.365318 (rank : 46)
Query Neighborhood Hits	140	Target Neighborhood Hits	898	Shared Neighborhood Hits	13
SwissProt Accessions	Q61526, Q3KQR1, Q68J64, Q810U8, Q8K317	Gene names	Erbb3
Domain Architecture	No domain graphic available
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Glial growth factor receptor).

NEK11_HUMAN
NC score	0.003927 (rank : 308)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	140	Target Neighborhood Hits	1043	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NG66, Q5JPC0, Q8NG65, Q8TBY1, Q9H5F4	Gene names	NEK11
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase Nek11 (EC 2.7.11.1) (NimA-related protein kinase 11) (Never in mitosis A-related kinase 11).

ERBB3_HUMAN
NC score	0.003923 (rank : 309)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	140	Target Neighborhood Hits	918	Shared Neighborhood Hits	13
SwissProt Accessions	P21860	Gene names	ERBB3, HER3
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-3 precursor (EC 2.7.10.1) (c- erbB3) (Tyrosine kinase-type cell surface receptor HER3).

SRMS_HUMAN
NC score	0.003391 (rank : 310)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	140	Target Neighborhood Hits	946	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

ITA2B_MOUSE
NC score	0.002327 (rank : 311)	θ value	8.99809 (rank : 130)
Query Neighborhood Hits	140	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QUM0, Q64229, Q9Z2M0	Gene names	Itga2b
Domain Architecture
Description	Integrin alpha-IIb precursor (Platelet membrane glycoprotein IIb) (GPalpha IIb) (GPIIb) (CD41 antigen) [Contains: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain].