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Network neighborhood for query Sequence : STA5B_HUMAN

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STA5B_HUMAN
SwissProt Accessions	P51692, Q8WWS8	Gene names	STAT5B
Domain Architecture
Description	Signal transducer and activator of transcription 5B.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

STA5A_HUMAN
θ value	0 (rank : 1)	NC score	0.994214 (rank : 4)
Query Neighborhood Hits	103	Target Neighborhood Hits	140	Shared Neighborhood Hits	89
SwissProt Accessions	P42229	Gene names	STAT5A, STAT5
Domain Architecture
Description	Signal transducer and activator of transcription 5A.

STA5A_MOUSE
θ value	0 (rank : 2)	NC score	0.994843 (rank : 3)
Query Neighborhood Hits	103	Target Neighborhood Hits	128	Shared Neighborhood Hits	82
SwissProt Accessions	P42230	Gene names	Stat5a, Mgf, Mpf
Domain Architecture
Description	Signal transducer and activator of transcription 5A (Mammary gland factor).

STA5B_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	103	Target Neighborhood Hits	103	Shared Neighborhood Hits	103
SwissProt Accessions	P51692, Q8WWS8	Gene names	STAT5B
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STA5B_MOUSE
θ value	0 (rank : 4)	NC score	0.997104 (rank : 2)
Query Neighborhood Hits	103	Target Neighborhood Hits	124	Shared Neighborhood Hits	91
SwissProt Accessions	P42232, Q541Q5, Q60804, Q8K3Q1, Q9JKM1	Gene names	Stat5b
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STAT6_HUMAN
θ value	2.13557e-126 (rank : 5)	NC score	0.940930 (rank : 6)
Query Neighborhood Hits	103	Target Neighborhood Hits	132	Shared Neighborhood Hits	23
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

STAT6_MOUSE
θ value	1.05987e-125 (rank : 6)	NC score	0.947292 (rank : 5)
Query Neighborhood Hits	103	Target Neighborhood Hits	78	Shared Neighborhood Hits	20
SwissProt Accessions	P52633	Gene names	Stat6
Domain Architecture
Description	Signal transducer and transcription activator 6.

STAT4_HUMAN
θ value	2.64101e-84 (rank : 7)	NC score	0.898109 (rank : 8)
Query Neighborhood Hits	103	Target Neighborhood Hits	91	Shared Neighborhood Hits	28
SwissProt Accessions	Q14765, Q96NZ6	Gene names	STAT4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STAT3_HUMAN
θ value	4.50487e-84 (rank : 8)	NC score	0.892413 (rank : 9)
Query Neighborhood Hits	103	Target Neighborhood Hits	155	Shared Neighborhood Hits	34
SwissProt Accessions	P40763, O14916, Q9BW54	Gene names	STAT3, APRF
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT3_MOUSE
θ value	4.50487e-84 (rank : 9)	NC score	0.892411 (rank : 10)
Query Neighborhood Hits	103	Target Neighborhood Hits	155	Shared Neighborhood Hits	34
SwissProt Accessions	P42227	Gene names	Stat3, Aprf
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT4_MOUSE
θ value	5.50685e-82 (rank : 10)	NC score	0.902819 (rank : 7)
Query Neighborhood Hits	103	Target Neighborhood Hits	73	Shared Neighborhood Hits	28
SwissProt Accessions	P42228	Gene names	Stat4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STAT1_HUMAN
θ value	3.69378e-78 (rank : 11)	NC score	0.889328 (rank : 11)
Query Neighborhood Hits	103	Target Neighborhood Hits	128	Shared Neighborhood Hits	41
SwissProt Accessions	P42224	Gene names	STAT1
Domain Architecture
Description	Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84).

STAT1_MOUSE
θ value	6.96618e-77 (rank : 12)	NC score	0.886631 (rank : 12)
Query Neighborhood Hits	103	Target Neighborhood Hits	151	Shared Neighborhood Hits	42
SwissProt Accessions	P42225	Gene names	Stat1
Domain Architecture
Description	Signal transducer and activator of transcription 1.

STAT2_HUMAN
θ value	4.39379e-55 (rank : 13)	NC score	0.875535 (rank : 13)
Query Neighborhood Hits	103	Target Neighborhood Hits	99	Shared Neighborhood Hits	29
SwissProt Accessions	P52630, Q16430, Q16431	Gene names	STAT2
Domain Architecture
Description	Signal transducer and activator of transcription 2 (p113).

STAT2_MOUSE
θ value	2.3352e-48 (rank : 14)	NC score	0.821279 (rank : 14)
Query Neighborhood Hits	103	Target Neighborhood Hits	175	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

GOGB1_HUMAN
θ value	7.1131e-05 (rank : 15)	NC score	0.085881 (rank : 16)
Query Neighborhood Hits	103	Target Neighborhood Hits	2297	Shared Neighborhood Hits	82
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CP135_HUMAN
θ value	0.00509761 (rank : 16)	NC score	0.071748 (rank : 24)
Query Neighborhood Hits	103	Target Neighborhood Hits	1290	Shared Neighborhood Hits	71
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CI093_HUMAN
θ value	0.00665767 (rank : 17)	NC score	0.079062 (rank : 18)
Query Neighborhood Hits	103	Target Neighborhood Hits	1088	Shared Neighborhood Hits	66
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CP250_HUMAN
θ value	0.0563607 (rank : 18)	NC score	0.068214 (rank : 28)
Query Neighborhood Hits	103	Target Neighborhood Hits	1805	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

RIMB1_MOUSE
θ value	0.0563607 (rank : 19)	NC score	0.075103 (rank : 21)
Query Neighborhood Hits	103	Target Neighborhood Hits	1376	Shared Neighborhood Hits	66
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

GOGA1_HUMAN
θ value	0.0736092 (rank : 20)	NC score	0.055824 (rank : 49)
Query Neighborhood Hits	103	Target Neighborhood Hits	1222	Shared Neighborhood Hits	68
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

PCNT_HUMAN
θ value	0.0736092 (rank : 21)	NC score	0.074409 (rank : 22)
Query Neighborhood Hits	103	Target Neighborhood Hits	1551	Shared Neighborhood Hits	75
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

TRIPB_HUMAN
θ value	0.0736092 (rank : 22)	NC score	0.069848 (rank : 27)
Query Neighborhood Hits	103	Target Neighborhood Hits	1587	Shared Neighborhood Hits	75
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CENPF_HUMAN
θ value	0.0961366 (rank : 23)	NC score	0.065578 (rank : 32)
Query Neighborhood Hits	103	Target Neighborhood Hits	1932	Shared Neighborhood Hits	81
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CTRO_HUMAN
θ value	0.0961366 (rank : 24)	NC score	0.033457 (rank : 90)
Query Neighborhood Hits	103	Target Neighborhood Hits	2092	Shared Neighborhood Hits	71
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

SH22A_HUMAN
θ value	0.0961366 (rank : 25)	NC score	0.117191 (rank : 15)
Query Neighborhood Hits	103	Target Neighborhood Hits	144	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

HIP1_HUMAN
θ value	0.125558 (rank : 26)	NC score	0.061619 (rank : 41)
Query Neighborhood Hits	103	Target Neighborhood Hits	1016	Shared Neighborhood Hits	61
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

GOGA4_MOUSE
θ value	0.163984 (rank : 27)	NC score	0.067501 (rank : 29)
Query Neighborhood Hits	103	Target Neighborhood Hits	1939	Shared Neighborhood Hits	81
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

APOE_MOUSE
θ value	0.279714 (rank : 28)	NC score	0.053035 (rank : 59)
Query Neighborhood Hits	103	Target Neighborhood Hits	319	Shared Neighborhood Hits	48
SwissProt Accessions	P08226	Gene names	Apoe
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

CCD21_HUMAN
θ value	0.279714 (rank : 29)	NC score	0.061999 (rank : 38)
Query Neighborhood Hits	103	Target Neighborhood Hits	1228	Shared Neighborhood Hits	67
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

CP135_MOUSE
θ value	0.279714 (rank : 30)	NC score	0.062933 (rank : 37)
Query Neighborhood Hits	103	Target Neighborhood Hits	1278	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CTRO_MOUSE
θ value	0.365318 (rank : 31)	NC score	0.033836 (rank : 89)
Query Neighborhood Hits	103	Target Neighborhood Hits	2344	Shared Neighborhood Hits	72
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

HAPIP_HUMAN
θ value	0.47712 (rank : 32)	NC score	0.046067 (rank : 74)
Query Neighborhood Hits	103	Target Neighborhood Hits	350	Shared Neighborhood Hits	41
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

HSH2D_HUMAN
θ value	0.47712 (rank : 33)	NC score	0.071696 (rank : 25)
Query Neighborhood Hits	103	Target Neighborhood Hits	159	Shared Neighborhood Hits	22
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

P55G_HUMAN
θ value	0.47712 (rank : 34)	NC score	0.071821 (rank : 23)
Query Neighborhood Hits	103	Target Neighborhood Hits	451	Shared Neighborhood Hits	60
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	0.47712 (rank : 35)	NC score	0.077820 (rank : 20)
Query Neighborhood Hits	103	Target Neighborhood Hits	401	Shared Neighborhood Hits	60
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

CCD45_MOUSE
θ value	0.62314 (rank : 36)	NC score	0.061767 (rank : 40)
Query Neighborhood Hits	103	Target Neighborhood Hits	663	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CENPE_HUMAN
θ value	0.62314 (rank : 37)	NC score	0.047900 (rank : 69)
Query Neighborhood Hits	103	Target Neighborhood Hits	2060	Shared Neighborhood Hits	79
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

IFT74_HUMAN
θ value	0.62314 (rank : 38)	NC score	0.059694 (rank : 42)
Query Neighborhood Hits	103	Target Neighborhood Hits	949	Shared Neighborhood Hits	61
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

BPAEA_MOUSE
θ value	0.813845 (rank : 39)	NC score	0.047643 (rank : 70)
Query Neighborhood Hits	103	Target Neighborhood Hits	1480	Shared Neighborhood Hits	72
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CP250_MOUSE
θ value	0.813845 (rank : 40)	NC score	0.057368 (rank : 46)
Query Neighborhood Hits	103	Target Neighborhood Hits	1583	Shared Neighborhood Hits	73
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

DIDO1_HUMAN
θ value	0.813845 (rank : 41)	NC score	0.040955 (rank : 82)
Query Neighborhood Hits	103	Target Neighborhood Hits	960	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

GOGA4_HUMAN
θ value	0.813845 (rank : 42)	NC score	0.058262 (rank : 44)
Query Neighborhood Hits	103	Target Neighborhood Hits	2034	Shared Neighborhood Hits	77
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MRCKG_HUMAN
θ value	0.813845 (rank : 43)	NC score	0.020172 (rank : 103)
Query Neighborhood Hits	103	Target Neighborhood Hits	1519	Shared Neighborhood Hits	64
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

PLEC1_HUMAN
θ value	0.813845 (rank : 44)	NC score	0.045588 (rank : 76)
Query Neighborhood Hits	103	Target Neighborhood Hits	1326	Shared Neighborhood Hits	71
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

BRE1A_HUMAN
θ value	1.06291 (rank : 45)	NC score	0.061905 (rank : 39)
Query Neighborhood Hits	103	Target Neighborhood Hits	1071	Shared Neighborhood Hits	64
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

NUMA1_HUMAN
θ value	1.06291 (rank : 46)	NC score	0.058217 (rank : 45)
Query Neighborhood Hits	103	Target Neighborhood Hits	1523	Shared Neighborhood Hits	73
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

BRE1A_MOUSE
θ value	1.38821 (rank : 47)	NC score	0.055590 (rank : 52)
Query Neighborhood Hits	103	Target Neighborhood Hits	1025	Shared Neighborhood Hits	66
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

CHIN_HUMAN
θ value	1.38821 (rank : 48)	NC score	0.023066 (rank : 101)
Query Neighborhood Hits	103	Target Neighborhood Hits	227	Shared Neighborhood Hits	18
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

HMMR_MOUSE
θ value	1.38821 (rank : 49)	NC score	0.051683 (rank : 64)
Query Neighborhood Hits	103	Target Neighborhood Hits	1178	Shared Neighborhood Hits	72
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

HSH2D_MOUSE
θ value	1.38821 (rank : 50)	NC score	0.085155 (rank : 17)
Query Neighborhood Hits	103	Target Neighborhood Hits	124	Shared Neighborhood Hits	25
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

TFAP4_HUMAN
θ value	1.38821 (rank : 51)	NC score	0.078894 (rank : 19)
Query Neighborhood Hits	103	Target Neighborhood Hits	289	Shared Neighborhood Hits	42
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

GOGA2_MOUSE
θ value	1.81305 (rank : 52)	NC score	0.070894 (rank : 26)
Query Neighborhood Hits	103	Target Neighborhood Hits	944	Shared Neighborhood Hits	71
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

IFT74_MOUSE
θ value	1.81305 (rank : 53)	NC score	0.063210 (rank : 36)
Query Neighborhood Hits	103	Target Neighborhood Hits	939	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

SPTA1_HUMAN
θ value	1.81305 (rank : 54)	NC score	0.036277 (rank : 87)
Query Neighborhood Hits	103	Target Neighborhood Hits	748	Shared Neighborhood Hits	58
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

CHIN_MOUSE
θ value	2.36792 (rank : 55)	NC score	0.020450 (rank : 102)
Query Neighborhood Hits	103	Target Neighborhood Hits	229	Shared Neighborhood Hits	17
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

EEA1_HUMAN
θ value	2.36792 (rank : 56)	NC score	0.054050 (rank : 56)
Query Neighborhood Hits	103	Target Neighborhood Hits	1796	Shared Neighborhood Hits	77
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

HIP1R_HUMAN
θ value	2.36792 (rank : 57)	NC score	0.055203 (rank : 55)
Query Neighborhood Hits	103	Target Neighborhood Hits	809	Shared Neighborhood Hits	64
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

K1683_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.043180 (rank : 78)
Query Neighborhood Hits	103	Target Neighborhood Hits	240	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

SH3K1_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.011746 (rank : 109)
Query Neighborhood Hits	103	Target Neighborhood Hits	341	Shared Neighborhood Hits	20
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

DNMBP_HUMAN
θ value	3.0926 (rank : 60)	NC score	0.016763 (rank : 106)
Query Neighborhood Hits	103	Target Neighborhood Hits	413	Shared Neighborhood Hits	23
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

K22E_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.016422 (rank : 107)
Query Neighborhood Hits	103	Target Neighborhood Hits	515	Shared Neighborhood Hits	44
SwissProt Accessions	P35908	Gene names	KRT2A, KRT2E
Domain Architecture
Description	Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (K2e) (CK 2e).

LRSM1_HUMAN
θ value	3.0926 (rank : 62)	NC score	0.035567 (rank : 88)
Query Neighborhood Hits	103	Target Neighborhood Hits	1078	Shared Neighborhood Hits	62
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

MLL2_HUMAN
θ value	3.0926 (rank : 63)	NC score	0.041329 (rank : 81)
Query Neighborhood Hits	103	Target Neighborhood Hits	1788	Shared Neighborhood Hits	52
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MYH6_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.032577 (rank : 91)
Query Neighborhood Hits	103	Target Neighborhood Hits	1426	Shared Neighborhood Hits	65
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

P85A_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.056807 (rank : 48)
Query Neighborhood Hits	103	Target Neighborhood Hits	479	Shared Neighborhood Hits	57
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
θ value	3.0926 (rank : 66)	NC score	0.055500 (rank : 53)
Query Neighborhood Hits	103	Target Neighborhood Hits	435	Shared Neighborhood Hits	50
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

PPT2_HUMAN
θ value	3.0926 (rank : 67)	NC score	0.027418 (rank : 97)
Query Neighborhood Hits	103	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMR5, O14799, Q0P6K0, Q5JP13, Q5JP14, Q5JQF0, Q5SSX4, Q5SSX5, Q5SSX6, Q5STJ4, Q5STJ5, Q5STJ6, Q6FI80, Q99945	Gene names	PPT2
Domain Architecture
Description	Lysosomal thioesterase PPT2 precursor (EC 3.1.2.-) (PPT-2) (S- thioesterase G14).

CLCN2_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.005670 (rank : 110)
Query Neighborhood Hits	103	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0A1, Q9WUJ9	Gene names	Clcn2, Clc2
Domain Architecture
Description	Chloride channel protein 2 (ClC-2).

CNTRB_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.057102 (rank : 47)
Query Neighborhood Hits	103	Target Neighborhood Hits	690	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

HIP1R_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.053568 (rank : 58)
Query Neighborhood Hits	103	Target Neighborhood Hits	959	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

INCE_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.049659 (rank : 67)
Query Neighborhood Hits	103	Target Neighborhood Hits	978	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

KIF4A_MOUSE
θ value	4.03905 (rank : 72)	NC score	0.029751 (rank : 96)
Query Neighborhood Hits	103	Target Neighborhood Hits	1033	Shared Neighborhood Hits	64
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

MRCKB_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.023660 (rank : 100)
Query Neighborhood Hits	103	Target Neighborhood Hits	2239	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MY18A_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.039221 (rank : 84)
Query Neighborhood Hits	103	Target Neighborhood Hits	1929	Shared Neighborhood Hits	77
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH7_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.032056 (rank : 92)
Query Neighborhood Hits	103	Target Neighborhood Hits	1559	Shared Neighborhood Hits	69
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

P85B_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.067054 (rank : 31)
Query Neighborhood Hits	103	Target Neighborhood Hits	519	Shared Neighborhood Hits	66
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

RABE2_MOUSE
θ value	4.03905 (rank : 77)	NC score	0.051227 (rank : 65)
Query Neighborhood Hits	103	Target Neighborhood Hits	598	Shared Neighborhood Hits	66
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

SWP70_MOUSE
θ value	4.03905 (rank : 78)	NC score	0.047565 (rank : 71)
Query Neighborhood Hits	103	Target Neighborhood Hits	1097	Shared Neighborhood Hits	64
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

ANR26_HUMAN
θ value	5.27518 (rank : 79)	NC score	0.042085 (rank : 80)
Query Neighborhood Hits	103	Target Neighborhood Hits	1614	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

FOXP2_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.030504 (rank : 95)
Query Neighborhood Hits	103	Target Neighborhood Hits	366	Shared Neighborhood Hits	40
SwissProt Accessions	O15409, Q6ZND1, Q75MJ3, Q8IZE0, Q8N0W2, Q8N6B7, Q8N6B8, Q8NFQ1, Q8NFQ2, Q8NFQ3, Q8NFQ4, Q8TD74	Gene names	FOXP2, CAGH44, TNRC10
Domain Architecture
Description	Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat- containing gene 10 protein).

FOXP2_MOUSE
θ value	5.27518 (rank : 81)	NC score	0.031259 (rank : 93)
Query Neighborhood Hits	103	Target Neighborhood Hits	366	Shared Neighborhood Hits	39
SwissProt Accessions	P58463, Q6PD37, Q8C4F0, Q8R441	Gene names	Foxp2
Domain Architecture
Description	Forkhead box protein P2.

P85B_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.067170 (rank : 30)
Query Neighborhood Hits	103	Target Neighborhood Hits	543	Shared Neighborhood Hits	65
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PPT2_MOUSE
θ value	5.27518 (rank : 83)	NC score	0.017829 (rank : 105)
Query Neighborhood Hits	103	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	O35448, Q80WP5	Gene names	Ppt2
Domain Architecture
Description	Lysosomal thioesterase PPT2 precursor (EC 3.1.2.-) (PPT-2).

SOCS4_HUMAN
θ value	5.27518 (rank : 84)	NC score	0.036890 (rank : 86)
Query Neighborhood Hits	103	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXH5	Gene names	SOCS4, SOCS7
Domain Architecture
Description	Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7).

SOCS4_MOUSE
θ value	5.27518 (rank : 85)	NC score	0.039255 (rank : 83)
Query Neighborhood Hits	103	Target Neighborhood Hits	69	Shared Neighborhood Hits	19
SwissProt Accessions	Q91ZA6	Gene names	Socs4, Socs7
Domain Architecture
Description	Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7).

STK10_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.012574 (rank : 108)
Query Neighborhood Hits	103	Target Neighborhood Hits	1921	Shared Neighborhood Hits	70
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

APOE_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.030943 (rank : 94)
Query Neighborhood Hits	103	Target Neighborhood Hits	222	Shared Neighborhood Hits	32
SwissProt Accessions	P02649, Q9P2S4	Gene names	APOE
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

MACF1_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.045847 (rank : 75)
Query Neighborhood Hits	103	Target Neighborhood Hits	1341	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	6.88961 (rank : 89)	NC score	0.051920 (rank : 63)
Query Neighborhood Hits	103	Target Neighborhood Hits	1321	Shared Neighborhood Hits	73
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

RAD50_HUMAN
θ value	6.88961 (rank : 90)	NC score	0.048838 (rank : 68)
Query Neighborhood Hits	103	Target Neighborhood Hits	1317	Shared Neighborhood Hits	67
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RBM19_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.002291 (rank : 112)
Query Neighborhood Hits	103	Target Neighborhood Hits	331	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4C8, Q9BPY6, Q9UFN5	Gene names	RBM19, KIAA0682
Domain Architecture
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

REST_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.043893 (rank : 77)
Query Neighborhood Hits	103	Target Neighborhood Hits	1605	Shared Neighborhood Hits	67
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

SRMS_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.001410 (rank : 113)
Query Neighborhood Hits	103	Target Neighborhood Hits	946	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).

TRHY_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.052893 (rank : 60)
Query Neighborhood Hits	103	Target Neighborhood Hits	1385	Shared Neighborhood Hits	70
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

UBP24_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.003730 (rank : 111)
Query Neighborhood Hits	103	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

CCD46_HUMAN
θ value	8.99809 (rank : 96)	NC score	0.042650 (rank : 79)
Query Neighborhood Hits	103	Target Neighborhood Hits	1430	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

RBP24_HUMAN
θ value	8.99809 (rank : 97)	NC score	0.047288 (rank : 72)
Query Neighborhood Hits	103	Target Neighborhood Hits	1559	Shared Neighborhood Hits	74
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

ROCK2_MOUSE
θ value	8.99809 (rank : 98)	NC score	0.020147 (rank : 104)
Query Neighborhood Hits	103	Target Neighborhood Hits	2072	Shared Neighborhood Hits	72
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

RUFY1_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.036909 (rank : 85)
Query Neighborhood Hits	103	Target Neighborhood Hits	848	Shared Neighborhood Hits	61
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

SH22A_MOUSE
θ value	8.99809 (rank : 100)	NC score	0.063770 (rank : 34)
Query Neighborhood Hits	103	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

SOCS5_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.025890 (rank : 99)
Query Neighborhood Hits	103	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	O75159, Q8IYZ4	Gene names	SOCS5, CIS6, CISH5, CISH6, KIAA0671
Domain Architecture
Description	Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5) (Cytokine-inducible SH2 protein 6) (CIS-6).

SOCS5_MOUSE
θ value	8.99809 (rank : 102)	NC score	0.026110 (rank : 98)
Query Neighborhood Hits	103	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	O54928	Gene names	Socs5, Cish5
Domain Architecture
Description	Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5).

TUFT1_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.046442 (rank : 73)
Query Neighborhood Hits	103	Target Neighborhood Hits	686	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

CCD11_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.059612 (rank : 43)
Query Neighborhood Hits	103	Target Neighborhood Hits	822	Shared Neighborhood Hits	63
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

CCD27_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.064166 (rank : 33)
Query Neighborhood Hits	103	Target Neighborhood Hits	594	Shared Neighborhood Hits	58
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CCD27_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.053569 (rank : 57)
Query Neighborhood Hits	103	Target Neighborhood Hits	461	Shared Neighborhood Hits	50
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

CF060_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.063225 (rank : 35)
Query Neighborhood Hits	103	Target Neighborhood Hits	1270	Shared Neighborhood Hits	68
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

GOGA1_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.050949 (rank : 66)
Query Neighborhood Hits	103	Target Neighborhood Hits	994	Shared Neighborhood Hits	66
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

GOGA2_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.052205 (rank : 62)
Query Neighborhood Hits	103	Target Neighborhood Hits	856	Shared Neighborhood Hits	63
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

HMMR_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.055210 (rank : 54)
Query Neighborhood Hits	103	Target Neighborhood Hits	1082	Shared Neighborhood Hits	69
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

KTN1_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.055773 (rank : 51)
Query Neighborhood Hits	103	Target Neighborhood Hits	1197	Shared Neighborhood Hits	71
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

REST_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.052497 (rank : 61)
Query Neighborhood Hits	103	Target Neighborhood Hits	1506	Shared Neighborhood Hits	67
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

TPR_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.055822 (rank : 50)
Query Neighborhood Hits	103	Target Neighborhood Hits	1921	Shared Neighborhood Hits	73
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

Hits sorted by NC score

STA5B_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	103	Target Neighborhood Hits	103	Shared Neighborhood Hits	103
SwissProt Accessions	P51692, Q8WWS8	Gene names	STAT5B
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STA5B_MOUSE
NC score	0.997104 (rank : 2)	θ value	0 (rank : 4)
Query Neighborhood Hits	103	Target Neighborhood Hits	124	Shared Neighborhood Hits	91
SwissProt Accessions	P42232, Q541Q5, Q60804, Q8K3Q1, Q9JKM1	Gene names	Stat5b
Domain Architecture
Description	Signal transducer and activator of transcription 5B.

STA5A_MOUSE
NC score	0.994843 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	103	Target Neighborhood Hits	128	Shared Neighborhood Hits	82
SwissProt Accessions	P42230	Gene names	Stat5a, Mgf, Mpf
Domain Architecture
Description	Signal transducer and activator of transcription 5A (Mammary gland factor).

STA5A_HUMAN
NC score	0.994214 (rank : 4)	θ value	0 (rank : 1)
Query Neighborhood Hits	103	Target Neighborhood Hits	140	Shared Neighborhood Hits	89
SwissProt Accessions	P42229	Gene names	STAT5A, STAT5
Domain Architecture
Description	Signal transducer and activator of transcription 5A.

STAT6_MOUSE
NC score	0.947292 (rank : 5)	θ value	1.05987e-125 (rank : 6)
Query Neighborhood Hits	103	Target Neighborhood Hits	78	Shared Neighborhood Hits	20
SwissProt Accessions	P52633	Gene names	Stat6
Domain Architecture
Description	Signal transducer and transcription activator 6.

STAT6_HUMAN
NC score	0.940930 (rank : 6)	θ value	2.13557e-126 (rank : 5)
Query Neighborhood Hits	103	Target Neighborhood Hits	132	Shared Neighborhood Hits	23
SwissProt Accessions	P42226	Gene names	STAT6
Domain Architecture
Description	Signal transducer and activator of transcription 6 (IL-4 Stat).

STAT4_MOUSE
NC score	0.902819 (rank : 7)	θ value	5.50685e-82 (rank : 10)
Query Neighborhood Hits	103	Target Neighborhood Hits	73	Shared Neighborhood Hits	28
SwissProt Accessions	P42228	Gene names	Stat4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STAT4_HUMAN
NC score	0.898109 (rank : 8)	θ value	2.64101e-84 (rank : 7)
Query Neighborhood Hits	103	Target Neighborhood Hits	91	Shared Neighborhood Hits	28
SwissProt Accessions	Q14765, Q96NZ6	Gene names	STAT4
Domain Architecture
Description	Signal transducer and activator of transcription 4.

STAT3_HUMAN
NC score	0.892413 (rank : 9)	θ value	4.50487e-84 (rank : 8)
Query Neighborhood Hits	103	Target Neighborhood Hits	155	Shared Neighborhood Hits	34
SwissProt Accessions	P40763, O14916, Q9BW54	Gene names	STAT3, APRF
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT3_MOUSE
NC score	0.892411 (rank : 10)	θ value	4.50487e-84 (rank : 9)
Query Neighborhood Hits	103	Target Neighborhood Hits	155	Shared Neighborhood Hits	34
SwissProt Accessions	P42227	Gene names	Stat3, Aprf
Domain Architecture
Description	Signal transducer and activator of transcription 3 (Acute-phase response factor).

STAT1_HUMAN
NC score	0.889328 (rank : 11)	θ value	3.69378e-78 (rank : 11)
Query Neighborhood Hits	103	Target Neighborhood Hits	128	Shared Neighborhood Hits	41
SwissProt Accessions	P42224	Gene names	STAT1
Domain Architecture
Description	Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84).

STAT1_MOUSE
NC score	0.886631 (rank : 12)	θ value	6.96618e-77 (rank : 12)
Query Neighborhood Hits	103	Target Neighborhood Hits	151	Shared Neighborhood Hits	42
SwissProt Accessions	P42225	Gene names	Stat1
Domain Architecture
Description	Signal transducer and activator of transcription 1.

STAT2_HUMAN
NC score	0.875535 (rank : 13)	θ value	4.39379e-55 (rank : 13)
Query Neighborhood Hits	103	Target Neighborhood Hits	99	Shared Neighborhood Hits	29
SwissProt Accessions	P52630, Q16430, Q16431	Gene names	STAT2
Domain Architecture
Description	Signal transducer and activator of transcription 2 (p113).

STAT2_MOUSE
NC score	0.821279 (rank : 14)	θ value	2.3352e-48 (rank : 14)
Query Neighborhood Hits	103	Target Neighborhood Hits	175	Shared Neighborhood Hits	23
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

SH22A_HUMAN
NC score	0.117191 (rank : 15)	θ value	0.0961366 (rank : 25)
Query Neighborhood Hits	103	Target Neighborhood Hits	144	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NP31, O43817, Q9UPA7	Gene names	SH2D2A, SCAP, TSAD, VRAP
Domain Architecture
Description	SH2 domain protein 2A (T cell-specific adapter protein) (TSAd) (VEGF receptor-associated protein) (SH2 domain-containing adapter protein).

GOGB1_HUMAN
NC score	0.085881 (rank : 16)	θ value	7.1131e-05 (rank : 15)
Query Neighborhood Hits	103	Target Neighborhood Hits	2297	Shared Neighborhood Hits	82
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

HSH2D_MOUSE
NC score	0.085155 (rank : 17)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	103	Target Neighborhood Hits	124	Shared Neighborhood Hits	25
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

CI093_HUMAN
NC score	0.079062 (rank : 18)	θ value	0.00665767 (rank : 17)
Query Neighborhood Hits	103	Target Neighborhood Hits	1088	Shared Neighborhood Hits	66
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

TFAP4_HUMAN
NC score	0.078894 (rank : 19)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	103	Target Neighborhood Hits	289	Shared Neighborhood Hits	42
SwissProt Accessions	Q01664, O60409	Gene names	TFAP4
Domain Architecture
Description	Transcription factor AP-4 (Activating enhancer-binding protein 4).

P55G_MOUSE
NC score	0.077820 (rank : 20)	θ value	0.47712 (rank : 35)
Query Neighborhood Hits	103	Target Neighborhood Hits	401	Shared Neighborhood Hits	60
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

RIMB1_MOUSE
NC score	0.075103 (rank : 21)	θ value	0.0563607 (rank : 19)
Query Neighborhood Hits	103	Target Neighborhood Hits	1376	Shared Neighborhood Hits	66
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

PCNT_HUMAN
NC score	0.074409 (rank : 22)	θ value	0.0736092 (rank : 21)
Query Neighborhood Hits	103	Target Neighborhood Hits	1551	Shared Neighborhood Hits	75
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

P55G_HUMAN
NC score	0.071821 (rank : 23)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	103	Target Neighborhood Hits	451	Shared Neighborhood Hits	60
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

CP135_HUMAN
NC score	0.071748 (rank : 24)	θ value	0.00509761 (rank : 16)
Query Neighborhood Hits	103	Target Neighborhood Hits	1290	Shared Neighborhood Hits	71
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

HSH2D_HUMAN
NC score	0.071696 (rank : 25)	θ value	0.47712 (rank : 33)
Query Neighborhood Hits	103	Target Neighborhood Hits	159	Shared Neighborhood Hits	22
SwissProt Accessions	Q96JZ2, Q6ZNG7	Gene names	HSH2D, ALX
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

GOGA2_MOUSE
NC score	0.070894 (rank : 26)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	103	Target Neighborhood Hits	944	Shared Neighborhood Hits	71
SwissProt Accessions	Q921M4	Gene names	Golga2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130).

TRIPB_HUMAN
NC score	0.069848 (rank : 27)	θ value	0.0736092 (rank : 22)
Query Neighborhood Hits	103	Target Neighborhood Hits	1587	Shared Neighborhood Hits	75
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CP250_HUMAN
NC score	0.068214 (rank : 28)	θ value	0.0563607 (rank : 18)
Query Neighborhood Hits	103	Target Neighborhood Hits	1805	Shared Neighborhood Hits	75
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

GOGA4_MOUSE
NC score	0.067501 (rank : 29)	θ value	0.163984 (rank : 27)
Query Neighborhood Hits	103	Target Neighborhood Hits	1939	Shared Neighborhood Hits	81
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

P85B_HUMAN
NC score	0.067170 (rank : 30)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	103	Target Neighborhood Hits	543	Shared Neighborhood Hits	65
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
NC score	0.067054 (rank : 31)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	103	Target Neighborhood Hits	519	Shared Neighborhood Hits	66
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

CENPF_HUMAN
NC score	0.065578 (rank : 32)	θ value	0.0961366 (rank : 23)
Query Neighborhood Hits	103	Target Neighborhood Hits	1932	Shared Neighborhood Hits	81
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CCD27_HUMAN
NC score	0.064166 (rank : 33)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	103	Target Neighborhood Hits	594	Shared Neighborhood Hits	58
SwissProt Accessions	Q2M243, Q5TBV3, Q96M50	Gene names	CCDC27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

SH22A_MOUSE
NC score	0.063770 (rank : 34)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	103	Target Neighborhood Hits	179	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QXK9, Q9JHP6	Gene names	Sh2d2a, Lad, Ribp
Domain Architecture
Description	SH2 domain protein 2A (Lck-associated adapter protein) (Lad) (Rlk/Itk- binding protein) (Ribp).

CF060_HUMAN
NC score	0.063225 (rank : 35)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	103	Target Neighborhood Hits	1270	Shared Neighborhood Hits	68
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

IFT74_MOUSE
NC score	0.063210 (rank : 36)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	103	Target Neighborhood Hits	939	Shared Neighborhood Hits	65
SwissProt Accessions	Q8BKE9, Q80ZI3, Q9CSY1, Q9CUS0, Q9D9T5	Gene names	Ift74, Ccdc2, Cmg1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

CP135_MOUSE
NC score	0.062933 (rank : 37)	θ value	0.279714 (rank : 30)
Query Neighborhood Hits	103	Target Neighborhood Hits	1278	Shared Neighborhood Hits	73
SwissProt Accessions	Q6P5D4, Q6A030	Gene names	Cep135, Cep4, Kiaa0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

CCD21_HUMAN
NC score	0.061999 (rank : 38)	θ value	0.279714 (rank : 29)
Query Neighborhood Hits	103	Target Neighborhood Hits	1228	Shared Neighborhood Hits	67
SwissProt Accessions	Q6P2H3, Q5VY68, Q5VY70, Q9H6Q1, Q9H828, Q9UF52	Gene names	CCDC21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

BRE1A_HUMAN
NC score	0.061905 (rank : 39)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	103	Target Neighborhood Hits	1071	Shared Neighborhood Hits	64
SwissProt Accessions	Q5VTR2, Q69YL5, Q6P527, Q8N3J4, Q96JD3, Q9H9Y7, Q9HA51, Q9NUR4, Q9NWQ3, Q9NX83	Gene names	RNF20, BRE1A
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (hBRE1) (RING finger protein 20).

CCD45_MOUSE
NC score	0.061767 (rank : 40)	θ value	0.62314 (rank : 36)
Query Neighborhood Hits	103	Target Neighborhood Hits	663	Shared Neighborhood Hits	56
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

HIP1_HUMAN
NC score	0.061619 (rank : 41)	θ value	0.125558 (rank : 26)
Query Neighborhood Hits	103	Target Neighborhood Hits	1016	Shared Neighborhood Hits	61
SwissProt Accessions	O00291, O00328, Q8TDL4	Gene names	HIP1
Domain Architecture
Description	Huntingtin-interacting protein 1 (HIP-I).

IFT74_HUMAN
NC score	0.059694 (rank : 42)	θ value	0.62314 (rank : 38)
Query Neighborhood Hits	103	Target Neighborhood Hits	949	Shared Neighborhood Hits	61
SwissProt Accessions	Q96LB3, Q6PGQ8, Q9H643, Q9H8G7	Gene names	IFT74, CCDC2, CMG1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 74 homolog (Coiled-coil domain-containing protein 2) (Capillary morphogenesis protein 1) (CMG-1).

CCD11_HUMAN
NC score	0.059612 (rank : 43)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	103	Target Neighborhood Hits	822	Shared Neighborhood Hits	63
SwissProt Accessions	Q96M91	Gene names	CCDC11
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 11.

GOGA4_HUMAN
NC score	0.058262 (rank : 44)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	103	Target Neighborhood Hits	2034	Shared Neighborhood Hits	77
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

NUMA1_HUMAN
NC score	0.058217 (rank : 45)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	103	Target Neighborhood Hits	1523	Shared Neighborhood Hits	73
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

CP250_MOUSE
NC score	0.057368 (rank : 46)	θ value	0.813845 (rank : 40)
Query Neighborhood Hits	103	Target Neighborhood Hits	1583	Shared Neighborhood Hits	73
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

CNTRB_HUMAN
NC score	0.057102 (rank : 47)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	103	Target Neighborhood Hits	690	Shared Neighborhood Hits	65
SwissProt Accessions	Q8N137, Q331K3, Q69YV7, Q8NCB8, Q8WXV3, Q96CQ7, Q9C060	Gene names	CNTROB, LIP8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

P85A_HUMAN
NC score	0.056807 (rank : 48)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	103	Target Neighborhood Hits	479	Shared Neighborhood Hits	57
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

GOGA1_HUMAN
NC score	0.055824 (rank : 49)	θ value	0.0736092 (rank : 20)
Query Neighborhood Hits	103	Target Neighborhood Hits	1222	Shared Neighborhood Hits	68
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

TPR_HUMAN
NC score	0.055822 (rank : 50)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	103	Target Neighborhood Hits	1921	Shared Neighborhood Hits	73
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

KTN1_HUMAN
NC score	0.055773 (rank : 51)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	103	Target Neighborhood Hits	1197	Shared Neighborhood Hits	71
SwissProt Accessions	Q86UP2, Q13999, Q14707, Q15387, Q86W57	Gene names	KTN1, CG1, KIAA0004
Domain Architecture	No domain graphic available
Description	Kinectin (Kinesin receptor) (CG-1 antigen).

BRE1A_MOUSE
NC score	0.055590 (rank : 52)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	103	Target Neighborhood Hits	1025	Shared Neighborhood Hits	66
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

P85A_MOUSE
NC score	0.055500 (rank : 53)	θ value	3.0926 (rank : 66)
Query Neighborhood Hits	103	Target Neighborhood Hits	435	Shared Neighborhood Hits	50
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

HMMR_HUMAN
NC score	0.055210 (rank : 54)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	103	Target Neighborhood Hits	1082	Shared Neighborhood Hits	69
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

HIP1R_HUMAN
NC score	0.055203 (rank : 55)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	103	Target Neighborhood Hits	809	Shared Neighborhood Hits	64
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

EEA1_HUMAN
NC score	0.054050 (rank : 56)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	103	Target Neighborhood Hits	1796	Shared Neighborhood Hits	77
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

CCD27_MOUSE
NC score	0.053569 (rank : 57)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	103	Target Neighborhood Hits	461	Shared Neighborhood Hits	50
SwissProt Accessions	Q3V036	Gene names	Ccdc27
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 27.

HIP1R_MOUSE
NC score	0.053568 (rank : 58)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	103	Target Neighborhood Hits	959	Shared Neighborhood Hits	67
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

APOE_MOUSE
NC score	0.053035 (rank : 59)	θ value	0.279714 (rank : 28)
Query Neighborhood Hits	103	Target Neighborhood Hits	319	Shared Neighborhood Hits	48
SwissProt Accessions	P08226	Gene names	Apoe
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

TRHY_HUMAN
NC score	0.052893 (rank : 60)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	103	Target Neighborhood Hits	1385	Shared Neighborhood Hits	70
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

REST_MOUSE
NC score	0.052497 (rank : 61)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	103	Target Neighborhood Hits	1506	Shared Neighborhood Hits	67
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

GOGA2_HUMAN
NC score	0.052205 (rank : 62)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	103	Target Neighborhood Hits	856	Shared Neighborhood Hits	63
SwissProt Accessions	Q08379, Q9BRB0, Q9NYF9	Gene names	GOLGA2
Domain Architecture	No domain graphic available
Description	Golgin subfamily A member 2 (Cis-Golgi matrix protein GM130) (Gm130 autoantigen) (Golgin-95).

MACF4_HUMAN
NC score	0.051920 (rank : 63)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	103	Target Neighborhood Hits	1321	Shared Neighborhood Hits	73
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

HMMR_MOUSE
NC score	0.051683 (rank : 64)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	103	Target Neighborhood Hits	1178	Shared Neighborhood Hits	72
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

RABE2_MOUSE
NC score	0.051227 (rank : 65)	θ value	4.03905 (rank : 77)
Query Neighborhood Hits	103	Target Neighborhood Hits	598	Shared Neighborhood Hits	66
SwissProt Accessions	Q91WG2, Q99KN3	Gene names	Rabep2, Rabpt5b
Domain Architecture
Description	Rab GTPase-binding effector protein 2 (Rabaptin-5beta).

GOGA1_MOUSE
NC score	0.050949 (rank : 66)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	103	Target Neighborhood Hits	994	Shared Neighborhood Hits	66
SwissProt Accessions	Q9CW79, Q80YB0	Gene names	Golga1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

INCE_HUMAN
NC score	0.049659 (rank : 67)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	103	Target Neighborhood Hits	978	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

RAD50_HUMAN
NC score	0.048838 (rank : 68)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	103	Target Neighborhood Hits	1317	Shared Neighborhood Hits	67
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

CENPE_HUMAN
NC score	0.047900 (rank : 69)	θ value	0.62314 (rank : 37)
Query Neighborhood Hits	103	Target Neighborhood Hits	2060	Shared Neighborhood Hits	79
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

BPAEA_MOUSE
NC score	0.047643 (rank : 70)	θ value	0.813845 (rank : 39)
Query Neighborhood Hits	103	Target Neighborhood Hits	1480	Shared Neighborhood Hits	72
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

SWP70_MOUSE
NC score	0.047565 (rank : 71)	θ value	4.03905 (rank : 78)
Query Neighborhood Hits	103	Target Neighborhood Hits	1097	Shared Neighborhood Hits	64
SwissProt Accessions	Q6A028, O88443, Q3TQR6, Q3UCA3, Q6P1D0	Gene names	Swap70, Kiaa0640
Domain Architecture	No domain graphic available
Description	Switch-associated protein 70 (SWAP-70).

RBP24_HUMAN
NC score	0.047288 (rank : 72)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	103	Target Neighborhood Hits	1559	Shared Neighborhood Hits	74
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

TUFT1_HUMAN
NC score	0.046442 (rank : 73)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	103	Target Neighborhood Hits	686	Shared Neighborhood Hits	57
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

HAPIP_HUMAN
NC score	0.046067 (rank : 74)	θ value	0.47712 (rank : 32)
Query Neighborhood Hits	103	Target Neighborhood Hits	350	Shared Neighborhood Hits	41
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

MACF1_HUMAN
NC score	0.045847 (rank : 75)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	103	Target Neighborhood Hits	1341	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

PLEC1_HUMAN
NC score	0.045588 (rank : 76)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	103	Target Neighborhood Hits	1326	Shared Neighborhood Hits	71
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

REST_HUMAN
NC score	0.043893 (rank : 77)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	103	Target Neighborhood Hits	1605	Shared Neighborhood Hits	67
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

K1683_HUMAN
NC score	0.043180 (rank : 78)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	103	Target Neighborhood Hits	240	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H0B3, Q8N4G8, Q96M14, Q9C0I0	Gene names	KIAA1683
Domain Architecture	No domain graphic available
Description	Protein KIAA1683.

CCD46_HUMAN
NC score	0.042650 (rank : 79)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	103	Target Neighborhood Hits	1430	Shared Neighborhood Hits	72
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

ANR26_HUMAN
NC score	0.042085 (rank : 80)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	103	Target Neighborhood Hits	1614	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

MLL2_HUMAN
NC score	0.041329 (rank : 81)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	103	Target Neighborhood Hits	1788	Shared Neighborhood Hits	52
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

DIDO1_HUMAN
NC score	0.040955 (rank : 82)	θ value	0.813845 (rank : 41)
Query Neighborhood Hits	103	Target Neighborhood Hits	960	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BTC0, O15043, Q3ZTL7, Q3ZTL8, Q4VXS1, Q4VXS2, Q96D72, Q9BQW0, Q9BW03, Q9H4G6, Q9H4G7, Q9NTU8, Q9NUM8, Q9UFB6	Gene names	DIDO1, C20orf158, DATF1, KIAA0333
Domain Architecture
Description	Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1) (hDido1).

SOCS4_MOUSE
NC score	0.039255 (rank : 83)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	103	Target Neighborhood Hits	69	Shared Neighborhood Hits	19
SwissProt Accessions	Q91ZA6	Gene names	Socs4, Socs7
Domain Architecture
Description	Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7).

MY18A_HUMAN
NC score	0.039221 (rank : 84)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	103	Target Neighborhood Hits	1929	Shared Neighborhood Hits	77
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

RUFY1_HUMAN
NC score	0.036909 (rank : 85)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	103	Target Neighborhood Hits	848	Shared Neighborhood Hits	61
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

SOCS4_HUMAN
NC score	0.036890 (rank : 86)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	103	Target Neighborhood Hits	69	Shared Neighborhood Hits	18
SwissProt Accessions	Q8WXH5	Gene names	SOCS4, SOCS7
Domain Architecture
Description	Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7).

SPTA1_HUMAN
NC score	0.036277 (rank : 87)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	103	Target Neighborhood Hits	748	Shared Neighborhood Hits	58
SwissProt Accessions	P02549, Q15514, Q6LDY5	Gene names	SPTA1, SPTA
Domain Architecture
Description	Spectrin alpha chain, erythrocyte (Erythroid alpha-spectrin).

LRSM1_HUMAN
NC score	0.035567 (rank : 88)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	103	Target Neighborhood Hits	1078	Shared Neighborhood Hits	62
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

CTRO_MOUSE
NC score	0.033836 (rank : 89)	θ value	0.365318 (rank : 31)
Query Neighborhood Hits	103	Target Neighborhood Hits	2344	Shared Neighborhood Hits	72
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CTRO_HUMAN
NC score	0.033457 (rank : 90)	θ value	0.0961366 (rank : 24)
Query Neighborhood Hits	103	Target Neighborhood Hits	2092	Shared Neighborhood Hits	71
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

MYH6_HUMAN
NC score	0.032577 (rank : 91)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	103	Target Neighborhood Hits	1426	Shared Neighborhood Hits	65
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH7_HUMAN
NC score	0.032056 (rank : 92)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	103	Target Neighborhood Hits	1559	Shared Neighborhood Hits	69
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

FOXP2_MOUSE
NC score	0.031259 (rank : 93)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	103	Target Neighborhood Hits	366	Shared Neighborhood Hits	39
SwissProt Accessions	P58463, Q6PD37, Q8C4F0, Q8R441	Gene names	Foxp2
Domain Architecture
Description	Forkhead box protein P2.

APOE_HUMAN
NC score	0.030943 (rank : 94)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	103	Target Neighborhood Hits	222	Shared Neighborhood Hits	32
SwissProt Accessions	P02649, Q9P2S4	Gene names	APOE
Domain Architecture
Description	Apolipoprotein E precursor (Apo-E).

FOXP2_HUMAN
NC score	0.030504 (rank : 95)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	103	Target Neighborhood Hits	366	Shared Neighborhood Hits	40
SwissProt Accessions	O15409, Q6ZND1, Q75MJ3, Q8IZE0, Q8N0W2, Q8N6B7, Q8N6B8, Q8NFQ1, Q8NFQ2, Q8NFQ3, Q8NFQ4, Q8TD74	Gene names	FOXP2, CAGH44, TNRC10
Domain Architecture
Description	Forkhead box protein P2 (CAG repeat protein 44) (Trinucleotide repeat- containing gene 10 protein).

KIF4A_MOUSE
NC score	0.029751 (rank : 96)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	103	Target Neighborhood Hits	1033	Shared Neighborhood Hits	64
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

PPT2_HUMAN
NC score	0.027418 (rank : 97)	θ value	3.0926 (rank : 67)
Query Neighborhood Hits	103	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMR5, O14799, Q0P6K0, Q5JP13, Q5JP14, Q5JQF0, Q5SSX4, Q5SSX5, Q5SSX6, Q5STJ4, Q5STJ5, Q5STJ6, Q6FI80, Q99945	Gene names	PPT2
Domain Architecture
Description	Lysosomal thioesterase PPT2 precursor (EC 3.1.2.-) (PPT-2) (S- thioesterase G14).

SOCS5_MOUSE
NC score	0.026110 (rank : 98)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	103	Target Neighborhood Hits	93	Shared Neighborhood Hits	18
SwissProt Accessions	O54928	Gene names	Socs5, Cish5
Domain Architecture
Description	Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5).

SOCS5_HUMAN
NC score	0.025890 (rank : 99)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	103	Target Neighborhood Hits	91	Shared Neighborhood Hits	17
SwissProt Accessions	O75159, Q8IYZ4	Gene names	SOCS5, CIS6, CISH5, CISH6, KIAA0671
Domain Architecture
Description	Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2- containing protein 5) (Cytokine-inducible SH2 protein 6) (CIS-6).

MRCKB_HUMAN
NC score	0.023660 (rank : 100)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	103	Target Neighborhood Hits	2239	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

CHIN_HUMAN
NC score	0.023066 (rank : 101)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	103	Target Neighborhood Hits	227	Shared Neighborhood Hits	18
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_MOUSE
NC score	0.020450 (rank : 102)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	103	Target Neighborhood Hits	229	Shared Neighborhood Hits	17
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

MRCKG_HUMAN
NC score	0.020172 (rank : 103)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	103	Target Neighborhood Hits	1519	Shared Neighborhood Hits	64
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

ROCK2_MOUSE
NC score	0.020147 (rank : 104)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	103	Target Neighborhood Hits	2072	Shared Neighborhood Hits	72
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

PPT2_MOUSE
NC score	0.017829 (rank : 105)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	103	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	O35448, Q80WP5	Gene names	Ppt2
Domain Architecture
Description	Lysosomal thioesterase PPT2 precursor (EC 3.1.2.-) (PPT-2).

DNMBP_HUMAN
NC score	0.016763 (rank : 106)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	103	Target Neighborhood Hits	413	Shared Neighborhood Hits	23
SwissProt Accessions	Q6XZF7, Q8IVY3, Q9Y2L3	Gene names	DNMBP, KIAA1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

K22E_HUMAN
NC score	0.016422 (rank : 107)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	103	Target Neighborhood Hits	515	Shared Neighborhood Hits	44
SwissProt Accessions	P35908	Gene names	KRT2A, KRT2E
Domain Architecture
Description	Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (K2e) (CK 2e).

STK10_HUMAN
NC score	0.012574 (rank : 108)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	103	Target Neighborhood Hits	1921	Shared Neighborhood Hits	70
SwissProt Accessions	O94804, Q9UIW4	Gene names	STK10, LOK
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

SH3K1_HUMAN
NC score	0.011746 (rank : 109)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	103	Target Neighborhood Hits	341	Shared Neighborhood Hits	20
SwissProt Accessions	Q96B97, Q8IWX6, Q8IX98, Q96RN4, Q9NYR0	Gene names	SH3KBP1, CIN85
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (Cbl-interacting protein of 85 kDa) (Human Src-family kinase-binding protein 1) (HSB-1) (CD2-binding protein 3) (CD2BP3).

CLCN2_MOUSE
NC score	0.005670 (rank : 110)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	103	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q9R0A1, Q9WUJ9	Gene names	Clcn2, Clc2
Domain Architecture
Description	Chloride channel protein 2 (ClC-2).

UBP24_HUMAN
NC score	0.003730 (rank : 111)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	103	Target Neighborhood Hits	96	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPU5, Q6ZSY2, Q8N2Y4, Q9NXD1	Gene names	USP24, KIAA1057
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 24 (EC 3.1.2.15) (Ubiquitin thioesterase 24) (Ubiquitin-specific-processing protease 24) (Deubiquitinating enzyme 24).

RBM19_HUMAN
NC score	0.002291 (rank : 112)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	103	Target Neighborhood Hits	331	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y4C8, Q9BPY6, Q9UFN5	Gene names	RBM19, KIAA0682
Domain Architecture
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

SRMS_HUMAN
NC score	0.001410 (rank : 113)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	103	Target Neighborhood Hits	946	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H3Y6	Gene names	SRMS, C20orf148
Domain Architecture
Description	Tyrosine-protein kinase Srms (EC 2.7.10.2).