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Network neighborhood for query Sequence : BORG1_MOUSE

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BORG1_MOUSE
SwissProt Accessions	Q8JZX9	Gene names	Cdc42ep2, Borg1, Cep2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

BORG1_MOUSE
θ value	2.22025e-107 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	Q8JZX9	Gene names	Cdc42ep2, Borg1, Cep2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

BORG1_HUMAN
θ value	3.91911e-104 (rank : 2)	NC score	0.983409 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	67	Shared Neighborhood Hits	18
SwissProt Accessions	O14613, Q9UNS0	Gene names	CDC42EP2, BORG1, CEP2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

BORG2_MOUSE
θ value	5.22648e-32 (rank : 3)	NC score	0.895605 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CQC5, Q3UD77, Q8BVR7	Gene names	Cdc42ep3, Borg2, Cep3
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 3 (Binder of Rho GTPases 2).

BORG2_HUMAN
θ value	1.28732e-30 (rank : 4)	NC score	0.894037 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKI2, O95353, Q9UQJ0	Gene names	CDC42EP3, BORG2, CEP3
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 3 (Binder of Rho GTPases 2) (MSE55-related Cdc42-binding protein).

BORG4_HUMAN
θ value	1.68911e-14 (rank : 5)	NC score	0.700674 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H3Q1, O95828, Q96FT3	Gene names	CDC42EP4, BORG4, CEP4
Domain Architecture
Description	Cdc42 effector protein 4 (Binder of Rho GTPases 4).

BORG4_MOUSE
θ value	3.76295e-14 (rank : 6)	NC score	0.697443 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JM96, Q3TNF3, Q9QZT8	Gene names	Cdc42ep4, Borg4, Cep4
Domain Architecture
Description	Cdc42 effector protein 4 (Binder of Rho GTPases 4).

BORG5_HUMAN
θ value	3.29651e-10 (rank : 7)	NC score	0.661056 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	135	Shared Neighborhood Hits	11
SwissProt Accessions	Q00587, Q96GN1	Gene names	CDC42EP1, BORG5, CEP1, MSE55
Domain Architecture
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55).

BORG5_MOUSE
θ value	4.30538e-10 (rank : 8)	NC score	0.665552 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	61	Shared Neighborhood Hits	11
SwissProt Accessions	Q91W92, Q9D8M1	Gene names	Cdc42ep1, Borg5, Cep1
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5).

BORG3_HUMAN
θ value	4.92598e-06 (rank : 9)	NC score	0.625069 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NZY7, Q8TB51	Gene names	CDC42EP5, BORG3, CEP5
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 5 (Binder of Rho GTPases 3).

BORG3_MOUSE
θ value	6.43352e-06 (rank : 10)	NC score	0.614736 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0X0, Q3SYK1, Q9QZT9	Gene names	Cdc42ep5, Borg3, Cep5
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 5 (Binder of Rho GTPases 3).

SON_HUMAN
θ value	0.125558 (rank : 11)	NC score	0.039023 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	1568	Shared Neighborhood Hits	10
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

PKN3_MOUSE
θ value	1.81305 (rank : 12)	NC score	0.005811 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	1009	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

ZFHX2_HUMAN
θ value	2.36792 (rank : 13)	NC score	0.024557 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	1178	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

MAGC1_HUMAN
θ value	3.0926 (rank : 14)	NC score	0.011891 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	431	Shared Neighborhood Hits	4
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

PAK2_HUMAN
θ value	4.03905 (rank : 15)	NC score	0.005196 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	862	Shared Neighborhood Hits	6
SwissProt Accessions	Q13177, Q13154	Gene names	PAK2
Domain Architecture
Description	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (p21-activated kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase).

PAK2_MOUSE
θ value	4.03905 (rank : 16)	NC score	0.005201 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	858	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CIN4	Gene names	Pak2
Domain Architecture
Description	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (p21-activated kinase 2) (PAK-2).

RAPH1_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.022008 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	593	Shared Neighborhood Hits	8
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

MRCKB_HUMAN
θ value	5.27518 (rank : 18)	NC score	0.003975 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	2239	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

SIGL6_HUMAN
θ value	5.27518 (rank : 19)	NC score	0.008966 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	233	Shared Neighborhood Hits	2
SwissProt Accessions	O43699, O15388, O43700	Gene names	SIGLEC6, CD33L, CD33L1, OBBP1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 6 precursor (Siglec-6) (Obesity- binding protein 1) (OB-BP1) (CD33 antigen-like 1) (CDw327 antigen).

NID2_HUMAN
θ value	6.88961 (rank : 20)	NC score	0.004526 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	456	Shared Neighborhood Hits	4
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

AP180_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.012264 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

MYO15_MOUSE
θ value	8.99809 (rank : 22)	NC score	0.005234 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	467	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

SCN3A_HUMAN
θ value	8.99809 (rank : 23)	NC score	0.005951 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

ZN449_HUMAN
θ value	8.99809 (rank : 24)	NC score	-0.001046 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	758	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P9G9, Q5JRZ8, Q6NZX2, Q8N3Q1, Q8TED7	Gene names	ZNF449, ZSCAN19
Domain Architecture	No domain graphic available
Description	Zinc finger protein 449 (Zinc finger and SCAN domain-containing protein 19).

Hits sorted by NC score

BORG1_MOUSE
NC score	0.999962 (rank : 1)	θ value	2.22025e-107 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	Q8JZX9	Gene names	Cdc42ep2, Borg1, Cep2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

BORG1_HUMAN
NC score	0.983409 (rank : 2)	θ value	3.91911e-104 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	67	Shared Neighborhood Hits	18
SwissProt Accessions	O14613, Q9UNS0	Gene names	CDC42EP2, BORG1, CEP2
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 2 (Binder of Rho GTPases 1).

BORG2_MOUSE
NC score	0.895605 (rank : 3)	θ value	5.22648e-32 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CQC5, Q3UD77, Q8BVR7	Gene names	Cdc42ep3, Borg2, Cep3
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 3 (Binder of Rho GTPases 2).

BORG2_HUMAN
NC score	0.894037 (rank : 4)	θ value	1.28732e-30 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UKI2, O95353, Q9UQJ0	Gene names	CDC42EP3, BORG2, CEP3
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 3 (Binder of Rho GTPases 2) (MSE55-related Cdc42-binding protein).

BORG4_HUMAN
NC score	0.700674 (rank : 5)	θ value	1.68911e-14 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H3Q1, O95828, Q96FT3	Gene names	CDC42EP4, BORG4, CEP4
Domain Architecture
Description	Cdc42 effector protein 4 (Binder of Rho GTPases 4).

BORG4_MOUSE
NC score	0.697443 (rank : 6)	θ value	3.76295e-14 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JM96, Q3TNF3, Q9QZT8	Gene names	Cdc42ep4, Borg4, Cep4
Domain Architecture
Description	Cdc42 effector protein 4 (Binder of Rho GTPases 4).

BORG5_MOUSE
NC score	0.665552 (rank : 7)	θ value	4.30538e-10 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	61	Shared Neighborhood Hits	11
SwissProt Accessions	Q91W92, Q9D8M1	Gene names	Cdc42ep1, Borg5, Cep1
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5).

BORG5_HUMAN
NC score	0.661056 (rank : 8)	θ value	3.29651e-10 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	135	Shared Neighborhood Hits	11
SwissProt Accessions	Q00587, Q96GN1	Gene names	CDC42EP1, BORG5, CEP1, MSE55
Domain Architecture
Description	Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55).

BORG3_HUMAN
NC score	0.625069 (rank : 9)	θ value	4.92598e-06 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	36	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NZY7, Q8TB51	Gene names	CDC42EP5, BORG3, CEP5
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 5 (Binder of Rho GTPases 3).

BORG3_MOUSE
NC score	0.614736 (rank : 10)	θ value	6.43352e-06 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0X0, Q3SYK1, Q9QZT9	Gene names	Cdc42ep5, Borg3, Cep5
Domain Architecture	No domain graphic available
Description	Cdc42 effector protein 5 (Binder of Rho GTPases 3).

SON_HUMAN
NC score	0.039023 (rank : 11)	θ value	0.125558 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	1568	Shared Neighborhood Hits	10
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ZFHX2_HUMAN
NC score	0.024557 (rank : 12)	θ value	2.36792 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	1178	Shared Neighborhood Hits	7
SwissProt Accessions	Q9C0A1	Gene names	ZFHX2, KIAA1762
Domain Architecture
Description	Zinc finger homeobox protein 2.

RAPH1_HUMAN
NC score	0.022008 (rank : 13)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	593	Shared Neighborhood Hits	8
SwissProt Accessions	Q70E73, Q96Q37, Q9C0I2	Gene names	RAPH1, ALS2CR9, KIAA1681, LPD, PREL2, RMO1
Domain Architecture	No domain graphic available
Description	Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate 9 gene protein).

AP180_HUMAN
NC score	0.012264 (rank : 14)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	O60641, Q5JX13, Q68DL9, Q6P9D3, Q9NTY7	Gene names	SNAP91, KIAA0656
Domain Architecture
Description	Clathrin coat assembly protein AP180 (Clathrin coat-associated protein AP180) (91 kDa synaptosomal-associated protein).

MAGC1_HUMAN
NC score	0.011891 (rank : 15)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	431	Shared Neighborhood Hits	4
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

SIGL6_HUMAN
NC score	0.008966 (rank : 16)	θ value	5.27518 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	233	Shared Neighborhood Hits	2
SwissProt Accessions	O43699, O15388, O43700	Gene names	SIGLEC6, CD33L, CD33L1, OBBP1
Domain Architecture
Description	Sialic acid-binding Ig-like lectin 6 precursor (Siglec-6) (Obesity- binding protein 1) (OB-BP1) (CD33 antigen-like 1) (CDw327 antigen).

SCN3A_HUMAN
NC score	0.005951 (rank : 17)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	115	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY46, Q16142, Q9BZB3, Q9C006, Q9NYK2, Q9UPD1, Q9Y6P4	Gene names	SCN3A, NAC3
Domain Architecture
Description	Sodium channel protein type 3 subunit alpha (Sodium channel protein type III subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.3) (Sodium channel protein, brain III subunit alpha) (Voltage- gated sodium channel subtype III).

PKN3_MOUSE
NC score	0.005811 (rank : 18)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	1009	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

MYO15_MOUSE
NC score	0.005234 (rank : 19)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	467	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PAK2_MOUSE
NC score	0.005201 (rank : 20)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	858	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CIN4	Gene names	Pak2
Domain Architecture
Description	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (p21-activated kinase 2) (PAK-2).

PAK2_HUMAN
NC score	0.005196 (rank : 21)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	862	Shared Neighborhood Hits	6
SwissProt Accessions	Q13177, Q13154	Gene names	PAK2
Domain Architecture
Description	Serine/threonine-protein kinase PAK 2 (EC 2.7.11.1) (p21-activated kinase 2) (PAK-2) (PAK65) (Gamma-PAK) (S6/H4 kinase).

NID2_HUMAN
NC score	0.004526 (rank : 22)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	456	Shared Neighborhood Hits	4
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

MRCKB_HUMAN
NC score	0.003975 (rank : 23)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	2239	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

ZN449_HUMAN
NC score	-0.001046 (rank : 24)	θ value	8.99809 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	758	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P9G9, Q5JRZ8, Q6NZX2, Q8N3Q1, Q8TED7	Gene names	ZNF449, ZSCAN19
Domain Architecture	No domain graphic available
Description	Zinc finger protein 449 (Zinc finger and SCAN domain-containing protein 19).