Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : INOC1_MOUSE

For an explanation of this page, click here

INOC1_MOUSE
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

INOC1_HUMAN
θ value	0 (rank : 1)	NC score	0.996826 (rank : 2)
Query Neighborhood Hits	178	Target Neighborhood Hits	181	Shared Neighborhood Hits	149
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

INOC1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	178	Target Neighborhood Hits	178	Shared Neighborhood Hits	178
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

SMCA1_HUMAN
θ value	1.5555e-68 (rank : 3)	NC score	0.920806 (rank : 3)
Query Neighborhood Hits	178	Target Neighborhood Hits	105	Shared Neighborhood Hits	43
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA4_HUMAN
θ value	2.03155e-68 (rank : 4)	NC score	0.869011 (rank : 23)
Query Neighborhood Hits	178	Target Neighborhood Hits	597	Shared Neighborhood Hits	78
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SMCA1_MOUSE
θ value	7.71989e-68 (rank : 5)	NC score	0.917968 (rank : 8)
Query Neighborhood Hits	178	Target Neighborhood Hits	117	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SMCA2_HUMAN
θ value	1.11475e-66 (rank : 6)	NC score	0.878726 (rank : 16)
Query Neighborhood Hits	178	Target Neighborhood Hits	503	Shared Neighborhood Hits	72
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA5_HUMAN
θ value	7.2256e-66 (rank : 7)	NC score	0.920715 (rank : 4)
Query Neighborhood Hits	178	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA5_MOUSE
θ value	1.6097e-65 (rank : 8)	NC score	0.920522 (rank : 5)
Query Neighborhood Hits	178	Target Neighborhood Hits	80	Shared Neighborhood Hits	41
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

CHD2_HUMAN
θ value	3.84025e-59 (rank : 9)	NC score	0.894422 (rank : 10)
Query Neighborhood Hits	178	Target Neighborhood Hits	360	Shared Neighborhood Hits	67
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

SMRCD_HUMAN
θ value	1.45929e-58 (rank : 10)	NC score	0.920096 (rank : 6)
Query Neighborhood Hits	178	Target Neighborhood Hits	117	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

SMRCD_MOUSE
θ value	1.36585e-56 (rank : 11)	NC score	0.919634 (rank : 7)
Query Neighborhood Hits	178	Target Neighborhood Hits	96	Shared Neighborhood Hits	41
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

CHD1_HUMAN
θ value	3.974e-56 (rank : 12)	NC score	0.886752 (rank : 13)
Query Neighborhood Hits	178	Target Neighborhood Hits	337	Shared Neighborhood Hits	52
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
θ value	6.77864e-56 (rank : 13)	NC score	0.890328 (rank : 12)
Query Neighborhood Hits	178	Target Neighborhood Hits	266	Shared Neighborhood Hits	47
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

EP400_HUMAN
θ value	8.85319e-56 (rank : 14)	NC score	0.839559 (rank : 24)
Query Neighborhood Hits	178	Target Neighborhood Hits	556	Shared Neighborhood Hits	46
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EP400_MOUSE
θ value	1.15626e-55 (rank : 15)	NC score	0.832850 (rank : 25)
Query Neighborhood Hits	178	Target Neighborhood Hits	592	Shared Neighborhood Hits	49
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

CHD3_HUMAN
θ value	7.75577e-52 (rank : 16)	NC score	0.826167 (rank : 27)
Query Neighborhood Hits	178	Target Neighborhood Hits	397	Shared Neighborhood Hits	47
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD5_HUMAN
θ value	1.72781e-51 (rank : 17)	NC score	0.823742 (rank : 29)
Query Neighborhood Hits	178	Target Neighborhood Hits	349	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD4_HUMAN
θ value	1.61718e-49 (rank : 18)	NC score	0.824325 (rank : 28)
Query Neighborhood Hits	178	Target Neighborhood Hits	365	Shared Neighborhood Hits	53
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	1.61718e-49 (rank : 19)	NC score	0.820607 (rank : 30)
Query Neighborhood Hits	178	Target Neighborhood Hits	408	Shared Neighborhood Hits	56
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD6_HUMAN
θ value	8.02596e-49 (rank : 20)	NC score	0.878757 (rank : 15)
Query Neighborhood Hits	178	Target Neighborhood Hits	342	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD8_HUMAN
θ value	8.02596e-49 (rank : 21)	NC score	0.885483 (rank : 14)
Query Neighborhood Hits	178	Target Neighborhood Hits	235	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD9_HUMAN
θ value	1.97686e-47 (rank : 22)	NC score	0.874174 (rank : 18)
Query Neighborhood Hits	178	Target Neighborhood Hits	343	Shared Neighborhood Hits	54
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
θ value	4.40402e-47 (rank : 23)	NC score	0.869791 (rank : 22)
Query Neighborhood Hits	178	Target Neighborhood Hits	427	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

BTAF1_HUMAN
θ value	1.05066e-40 (rank : 24)	NC score	0.899749 (rank : 9)
Query Neighborhood Hits	178	Target Neighborhood Hits	97	Shared Neighborhood Hits	39
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

ERCC6_HUMAN
θ value	7.79185e-36 (rank : 25)	NC score	0.890484 (rank : 11)
Query Neighborhood Hits	178	Target Neighborhood Hits	247	Shared Neighborhood Hits	52
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

RA54B_HUMAN
θ value	2.68423e-28 (rank : 26)	NC score	0.874889 (rank : 17)
Query Neighborhood Hits	178	Target Neighborhood Hits	54	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RA54B_MOUSE
θ value	1.92365e-26 (rank : 27)	NC score	0.871223 (rank : 21)
Query Neighborhood Hits	178	Target Neighborhood Hits	59	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RAD54_HUMAN
θ value	1.92365e-26 (rank : 28)	NC score	0.872133 (rank : 19)
Query Neighborhood Hits	178	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RAD54_MOUSE
θ value	2.51237e-26 (rank : 29)	NC score	0.871698 (rank : 20)
Query Neighborhood Hits	178	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

TTF2_MOUSE
θ value	8.93572e-24 (rank : 30)	NC score	0.791640 (rank : 32)
Query Neighborhood Hits	178	Target Neighborhood Hits	364	Shared Neighborhood Hits	52
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

ATRX_MOUSE
θ value	3.39556e-23 (rank : 31)	NC score	0.691255 (rank : 36)
Query Neighborhood Hits	178	Target Neighborhood Hits	682	Shared Neighborhood Hits	92
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

TTF2_HUMAN
θ value	3.39556e-23 (rank : 32)	NC score	0.827995 (rank : 26)
Query Neighborhood Hits	178	Target Neighborhood Hits	98	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

ATRX_HUMAN
θ value	4.43474e-23 (rank : 33)	NC score	0.680342 (rank : 37)
Query Neighborhood Hits	178	Target Neighborhood Hits	842	Shared Neighborhood Hits	115
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

SMRA3_HUMAN
θ value	3.88503e-19 (rank : 34)	NC score	0.713568 (rank : 35)
Query Neighborhood Hits	178	Target Neighborhood Hits	265	Shared Neighborhood Hits	38
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

SMRA3_MOUSE
θ value	1.13037e-18 (rank : 35)	NC score	0.714470 (rank : 34)
Query Neighborhood Hits	178	Target Neighborhood Hits	267	Shared Neighborhood Hits	40
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SMAL1_HUMAN
θ value	6.20254e-17 (rank : 36)	NC score	0.787719 (rank : 33)
Query Neighborhood Hits	178	Target Neighborhood Hits	174	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SMAL1_MOUSE
θ value	2.60593e-15 (rank : 37)	NC score	0.792551 (rank : 31)
Query Neighborhood Hits	178	Target Neighborhood Hits	157	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

ANR26_MOUSE
θ value	0.00298849 (rank : 38)	NC score	0.049805 (rank : 117)
Query Neighborhood Hits	178	Target Neighborhood Hits	1554	Shared Neighborhood Hits	101
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

BPAEA_MOUSE
θ value	0.0113563 (rank : 39)	NC score	0.055839 (rank : 88)
Query Neighborhood Hits	178	Target Neighborhood Hits	1480	Shared Neighborhood Hits	97
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

TAOK1_HUMAN
θ value	0.0113563 (rank : 40)	NC score	0.023140 (rank : 190)
Query Neighborhood Hits	178	Target Neighborhood Hits	1734	Shared Neighborhood Hits	98
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

CCD91_HUMAN
θ value	0.0193708 (rank : 41)	NC score	0.068467 (rank : 60)
Query Neighborhood Hits	178	Target Neighborhood Hits	868	Shared Neighborhood Hits	89
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

MRCKB_HUMAN
θ value	0.0193708 (rank : 42)	NC score	0.029487 (rank : 175)
Query Neighborhood Hits	178	Target Neighborhood Hits	2239	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

CJ118_MOUSE
θ value	0.0252991 (rank : 43)	NC score	0.055490 (rank : 89)
Query Neighborhood Hits	178	Target Neighborhood Hits	1132	Shared Neighborhood Hits	90
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

EEA1_MOUSE
θ value	0.0252991 (rank : 44)	NC score	0.052253 (rank : 108)
Query Neighborhood Hits	178	Target Neighborhood Hits	1637	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

TAOK1_MOUSE
θ value	0.0252991 (rank : 45)	NC score	0.022079 (rank : 192)
Query Neighborhood Hits	178	Target Neighborhood Hits	1720	Shared Neighborhood Hits	95
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

KI21A_HUMAN
θ value	0.0330416 (rank : 46)	NC score	0.043007 (rank : 132)
Query Neighborhood Hits	178	Target Neighborhood Hits	1543	Shared Neighborhood Hits	95
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

SEMG2_HUMAN
θ value	0.0330416 (rank : 47)	NC score	0.061968 (rank : 69)
Query Neighborhood Hits	178	Target Neighborhood Hits	251	Shared Neighborhood Hits	25
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

UBP8_HUMAN
θ value	0.0330416 (rank : 48)	NC score	0.038517 (rank : 150)
Query Neighborhood Hits	178	Target Neighborhood Hits	751	Shared Neighborhood Hits	77
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

SM1L2_HUMAN
θ value	0.0961366 (rank : 49)	NC score	0.057755 (rank : 81)
Query Neighborhood Hits	178	Target Neighborhood Hits	1019	Shared Neighborhood Hits	91
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

GCC2_HUMAN
θ value	0.125558 (rank : 50)	NC score	0.050989 (rank : 111)
Query Neighborhood Hits	178	Target Neighborhood Hits	1558	Shared Neighborhood Hits	101
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
θ value	0.125558 (rank : 51)	NC score	0.050649 (rank : 112)
Query Neighborhood Hits	178	Target Neighborhood Hits	1559	Shared Neighborhood Hits	101
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

UBP10_HUMAN
θ value	0.125558 (rank : 52)	NC score	0.033176 (rank : 163)
Query Neighborhood Hits	178	Target Neighborhood Hits	153	Shared Neighborhood Hits	6
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

CT2NL_HUMAN
θ value	0.163984 (rank : 53)	NC score	0.058397 (rank : 77)
Query Neighborhood Hits	178	Target Neighborhood Hits	1059	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

LAMC2_HUMAN
θ value	0.163984 (rank : 54)	NC score	0.017528 (rank : 205)
Query Neighborhood Hits	178	Target Neighborhood Hits	715	Shared Neighborhood Hits	50
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

SKIL_MOUSE
θ value	0.163984 (rank : 55)	NC score	0.055412 (rank : 90)
Query Neighborhood Hits	178	Target Neighborhood Hits	719	Shared Neighborhood Hits	80
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

ANR26_HUMAN
θ value	0.21417 (rank : 56)	NC score	0.049741 (rank : 118)
Query Neighborhood Hits	178	Target Neighborhood Hits	1614	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CT2NL_MOUSE
θ value	0.21417 (rank : 57)	NC score	0.054073 (rank : 97)
Query Neighborhood Hits	178	Target Neighborhood Hits	902	Shared Neighborhood Hits	85
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CENPF_HUMAN
θ value	0.279714 (rank : 58)	NC score	0.046293 (rank : 123)
Query Neighborhood Hits	178	Target Neighborhood Hits	1932	Shared Neighborhood Hits	102
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

LIMA1_HUMAN
θ value	0.279714 (rank : 59)	NC score	0.040437 (rank : 142)
Query Neighborhood Hits	178	Target Neighborhood Hits	309	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

DDX41_HUMAN
θ value	0.365318 (rank : 60)	NC score	0.049991 (rank : 116)
Query Neighborhood Hits	178	Target Neighborhood Hits	111	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

DDX41_MOUSE
θ value	0.365318 (rank : 61)	NC score	0.053181 (rank : 102)
Query Neighborhood Hits	178	Target Neighborhood Hits	115	Shared Neighborhood Hits	22
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

DMD_MOUSE
θ value	0.365318 (rank : 62)	NC score	0.043590 (rank : 130)
Query Neighborhood Hits	178	Target Neighborhood Hits	1111	Shared Neighborhood Hits	82
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

CENPE_HUMAN
θ value	0.47712 (rank : 63)	NC score	0.050049 (rank : 115)
Query Neighborhood Hits	178	Target Neighborhood Hits	2060	Shared Neighborhood Hits	111
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

MACF1_HUMAN
θ value	0.47712 (rank : 64)	NC score	0.042099 (rank : 137)
Query Neighborhood Hits	178	Target Neighborhood Hits	1341	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	0.47712 (rank : 65)	NC score	0.044995 (rank : 128)
Query Neighborhood Hits	178	Target Neighborhood Hits	1321	Shared Neighborhood Hits	86
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

UB2L3_HUMAN
θ value	0.47712 (rank : 66)	NC score	0.021634 (rank : 193)
Query Neighborhood Hits	178	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	P68036, P51966, P70653, Q9HAV1	Gene names	UBE2L3, UBCE7, UBCH7
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 L3 (EC 6.3.2.19) (Ubiquitin-protein ligase L3) (Ubiquitin carrier protein L3) (UbcH7) (E2-F1) (L-UBC).

UB2L3_MOUSE
θ value	0.47712 (rank : 67)	NC score	0.021634 (rank : 194)
Query Neighborhood Hits	178	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	P68037, P51966, P70653, Q9HAV1	Gene names	Ube2l3, Ubce7
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 L3 (EC 6.3.2.19) (Ubiquitin-protein ligase L3) (Ubiquitin carrier protein L3) (UbcM4).

DDX51_HUMAN
θ value	0.62314 (rank : 68)	NC score	0.017759 (rank : 203)
Query Neighborhood Hits	178	Target Neighborhood Hits	332	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

DESP_HUMAN
θ value	0.62314 (rank : 69)	NC score	0.048032 (rank : 119)
Query Neighborhood Hits	178	Target Neighborhood Hits	1470	Shared Neighborhood Hits	101
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

KI21A_MOUSE
θ value	0.62314 (rank : 70)	NC score	0.033645 (rank : 162)
Query Neighborhood Hits	178	Target Neighborhood Hits	1317	Shared Neighborhood Hits	87
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

PPIG_HUMAN
θ value	0.62314 (rank : 71)	NC score	0.045938 (rank : 124)
Query Neighborhood Hits	178	Target Neighborhood Hits	670	Shared Neighborhood Hits	69
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

ZBT40_HUMAN
θ value	0.62314 (rank : 72)	NC score	-0.000356 (rank : 233)
Query Neighborhood Hits	178	Target Neighborhood Hits	949	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

CEP35_HUMAN
θ value	0.813845 (rank : 73)	NC score	0.054804 (rank : 91)
Query Neighborhood Hits	178	Target Neighborhood Hits	811	Shared Neighborhood Hits	77
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

CALI_HUMAN
θ value	1.06291 (rank : 74)	NC score	0.014558 (rank : 214)
Query Neighborhood Hits	178	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	Q13939, Q9BXG7	Gene names	CCIN
Domain Architecture
Description	Calicin.

MRCKB_MOUSE
θ value	1.06291 (rank : 75)	NC score	0.025095 (rank : 187)
Query Neighborhood Hits	178	Target Neighborhood Hits	2180	Shared Neighborhood Hits	101
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

SMC3_HUMAN
θ value	1.06291 (rank : 76)	NC score	0.053650 (rank : 99)
Query Neighborhood Hits	178	Target Neighborhood Hits	1186	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	1.06291 (rank : 77)	NC score	0.053518 (rank : 100)
Query Neighborhood Hits	178	Target Neighborhood Hits	1187	Shared Neighborhood Hits	97
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SPTB1_HUMAN
θ value	1.06291 (rank : 78)	NC score	0.032175 (rank : 168)
Query Neighborhood Hits	178	Target Neighborhood Hits	541	Shared Neighborhood Hits	61
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

SPTN2_HUMAN
θ value	1.06291 (rank : 79)	NC score	0.028516 (rank : 177)
Query Neighborhood Hits	178	Target Neighborhood Hits	535	Shared Neighborhood Hits	49
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

TRAK1_HUMAN
θ value	1.06291 (rank : 80)	NC score	0.041814 (rank : 138)
Query Neighborhood Hits	178	Target Neighborhood Hits	660	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

GOGA5_HUMAN
θ value	1.38821 (rank : 81)	NC score	0.043188 (rank : 131)
Query Neighborhood Hits	178	Target Neighborhood Hits	1168	Shared Neighborhood Hits	94
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

GOGB1_HUMAN
θ value	1.38821 (rank : 82)	NC score	0.052347 (rank : 107)
Query Neighborhood Hits	178	Target Neighborhood Hits	2297	Shared Neighborhood Hits	118
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

KCNN2_HUMAN
θ value	1.38821 (rank : 83)	NC score	0.019601 (rank : 199)
Query Neighborhood Hits	178	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_MOUSE
θ value	1.38821 (rank : 84)	NC score	0.019746 (rank : 198)
Query Neighborhood Hits	178	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

LRFN5_HUMAN
θ value	1.38821 (rank : 85)	NC score	0.005851 (rank : 226)
Query Neighborhood Hits	178	Target Neighborhood Hits	464	Shared Neighborhood Hits	6
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

SMC2_MOUSE
θ value	1.38821 (rank : 86)	NC score	0.054439 (rank : 93)
Query Neighborhood Hits	178	Target Neighborhood Hits	1131	Shared Neighborhood Hits	90
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SPTB2_HUMAN
θ value	1.38821 (rank : 87)	NC score	0.042192 (rank : 136)
Query Neighborhood Hits	178	Target Neighborhood Hits	748	Shared Neighborhood Hits	82
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

SPTB2_MOUSE
θ value	1.38821 (rank : 88)	NC score	0.039518 (rank : 146)
Query Neighborhood Hits	178	Target Neighborhood Hits	770	Shared Neighborhood Hits	78
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

CF182_HUMAN
θ value	1.81305 (rank : 89)	NC score	0.043845 (rank : 129)
Query Neighborhood Hits	178	Target Neighborhood Hits	474	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IYX8	Gene names	C6orf182
Domain Architecture	No domain graphic available
Description	Protein C6orf182.

CTRO_MOUSE
θ value	1.81305 (rank : 90)	NC score	0.024224 (rank : 188)
Query Neighborhood Hits	178	Target Neighborhood Hits	2344	Shared Neighborhood Hits	105
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

EXOC2_HUMAN
θ value	1.81305 (rank : 91)	NC score	0.019180 (rank : 201)
Query Neighborhood Hits	178	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KP1, Q5JPC8, Q96AN6, Q9NUZ8, Q9UJM7	Gene names	EXOC2, SEC5, SEC5L1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

HMMR_HUMAN
θ value	1.81305 (rank : 92)	NC score	0.045584 (rank : 125)
Query Neighborhood Hits	178	Target Neighborhood Hits	1082	Shared Neighborhood Hits	85
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

ITSN2_MOUSE
θ value	1.81305 (rank : 93)	NC score	0.032097 (rank : 169)
Query Neighborhood Hits	178	Target Neighborhood Hits	1371	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

NU153_HUMAN
θ value	1.81305 (rank : 94)	NC score	0.022684 (rank : 191)
Query Neighborhood Hits	178	Target Neighborhood Hits	227	Shared Neighborhood Hits	7
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

COCA1_HUMAN
θ value	2.36792 (rank : 95)	NC score	0.004092 (rank : 229)
Query Neighborhood Hits	178	Target Neighborhood Hits	458	Shared Neighborhood Hits	9
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

CR034_MOUSE
θ value	2.36792 (rank : 96)	NC score	0.040279 (rank : 144)
Query Neighborhood Hits	178	Target Neighborhood Hits	643	Shared Neighborhood Hits	76
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

DNJC8_MOUSE
θ value	2.36792 (rank : 97)	NC score	0.030465 (rank : 173)
Query Neighborhood Hits	178	Target Neighborhood Hits	392	Shared Neighborhood Hits	36
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

E41L2_MOUSE
θ value	2.36792 (rank : 98)	NC score	0.025229 (rank : 186)
Query Neighborhood Hits	178	Target Neighborhood Hits	459	Shared Neighborhood Hits	44
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

ITSN2_HUMAN
θ value	2.36792 (rank : 99)	NC score	0.031036 (rank : 172)
Query Neighborhood Hits	178	Target Neighborhood Hits	1173	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

KDEL2_HUMAN
θ value	2.36792 (rank : 100)	NC score	0.019337 (rank : 200)
Query Neighborhood Hits	178	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z4H8, Q6UWW2, Q6ZUM9, Q8N7L8, Q8NE24	Gene names	KDELC2
Domain Architecture	No domain graphic available
Description	KDEL motif-containing protein 2 precursor.

LRFN5_MOUSE
θ value	2.36792 (rank : 101)	NC score	0.004810 (rank : 228)
Query Neighborhood Hits	178	Target Neighborhood Hits	472	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

MPP10_HUMAN
θ value	2.36792 (rank : 102)	NC score	0.031077 (rank : 171)
Query Neighborhood Hits	178	Target Neighborhood Hits	306	Shared Neighborhood Hits	37
SwissProt Accessions	O00566	Gene names	MPHOSPH10, MPP10
Domain Architecture
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

MY18A_HUMAN
θ value	2.36792 (rank : 103)	NC score	0.046877 (rank : 121)
Query Neighborhood Hits	178	Target Neighborhood Hits	1929	Shared Neighborhood Hits	114
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SPEG_HUMAN
θ value	2.36792 (rank : 104)	NC score	0.001152 (rank : 231)
Query Neighborhood Hits	178	Target Neighborhood Hits	1762	Shared Neighborhood Hits	25
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CCDC6_HUMAN
θ value	3.0926 (rank : 105)	NC score	0.040250 (rank : 145)
Query Neighborhood Hits	178	Target Neighborhood Hits	723	Shared Neighborhood Hits	77
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

HPLN2_MOUSE
θ value	3.0926 (rank : 106)	NC score	0.005260 (rank : 227)
Query Neighborhood Hits	178	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

ITSN1_HUMAN
θ value	3.0926 (rank : 107)	NC score	0.032425 (rank : 166)
Query Neighborhood Hits	178	Target Neighborhood Hits	1757	Shared Neighborhood Hits	100
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

K0831_MOUSE
θ value	3.0926 (rank : 108)	NC score	0.034699 (rank : 159)
Query Neighborhood Hits	178	Target Neighborhood Hits	277	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CDJ3, Q69ZY1, Q6PFY6, Q8C6N0, Q8R3M3	Gene names	Kiaa0831, D14Ertd436e
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

MRCKA_HUMAN
θ value	3.0926 (rank : 109)	NC score	0.018609 (rank : 202)
Query Neighborhood Hits	178	Target Neighborhood Hits	1999	Shared Neighborhood Hits	95
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

PARD3_HUMAN
θ value	3.0926 (rank : 110)	NC score	0.015036 (rank : 213)
Query Neighborhood Hits	178	Target Neighborhood Hits	312	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

ARI5B_HUMAN
θ value	4.03905 (rank : 111)	NC score	0.045135 (rank : 127)
Query Neighborhood Hits	178	Target Neighborhood Hits	328	Shared Neighborhood Hits	17
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

CING_MOUSE
θ value	4.03905 (rank : 112)	NC score	0.042541 (rank : 134)
Query Neighborhood Hits	178	Target Neighborhood Hits	1432	Shared Neighborhood Hits	103
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CLSPN_HUMAN
θ value	4.03905 (rank : 113)	NC score	0.028353 (rank : 179)
Query Neighborhood Hits	178	Target Neighborhood Hits	433	Shared Neighborhood Hits	64
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

DNJC8_HUMAN
θ value	4.03905 (rank : 114)	NC score	0.026788 (rank : 183)
Query Neighborhood Hits	178	Target Neighborhood Hits	380	Shared Neighborhood Hits	32
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

GBF1_HUMAN
θ value	4.03905 (rank : 115)	NC score	0.010898 (rank : 218)
Query Neighborhood Hits	178	Target Neighborhood Hits	142	Shared Neighborhood Hits	8
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

GRIN1_HUMAN
θ value	4.03905 (rank : 116)	NC score	0.029072 (rank : 176)
Query Neighborhood Hits	178	Target Neighborhood Hits	681	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

K0157_MOUSE
θ value	4.03905 (rank : 117)	NC score	0.021602 (rank : 195)
Query Neighborhood Hits	178	Target Neighborhood Hits	116	Shared Neighborhood Hits	9
SwissProt Accessions	Q3TCJ1, Q3TB08, Q8K0R4	Gene names	Kiaa0157
Domain Architecture	No domain graphic available
Description	Protein KIAA0157.

MYH11_HUMAN
θ value	4.03905 (rank : 118)	NC score	0.040355 (rank : 143)
Query Neighborhood Hits	178	Target Neighborhood Hits	1806	Shared Neighborhood Hits	111
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH13_HUMAN
θ value	4.03905 (rank : 119)	NC score	0.036795 (rank : 155)
Query Neighborhood Hits	178	Target Neighborhood Hits	1504	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

SMC2_HUMAN
θ value	4.03905 (rank : 120)	NC score	0.054420 (rank : 94)
Query Neighborhood Hits	178	Target Neighborhood Hits	1405	Shared Neighborhood Hits	103
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

TR150_HUMAN
θ value	4.03905 (rank : 121)	NC score	0.041608 (rank : 140)
Query Neighborhood Hits	178	Target Neighborhood Hits	313	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

CI093_HUMAN
θ value	5.27518 (rank : 122)	NC score	0.041193 (rank : 141)
Query Neighborhood Hits	178	Target Neighborhood Hits	1088	Shared Neighborhood Hits	89
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CTGE5_MOUSE
θ value	5.27518 (rank : 123)	NC score	0.038372 (rank : 151)
Query Neighborhood Hits	178	Target Neighborhood Hits	928	Shared Neighborhood Hits	92
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

CTRO_HUMAN
θ value	5.27518 (rank : 124)	NC score	0.020521 (rank : 196)
Query Neighborhood Hits	178	Target Neighborhood Hits	2092	Shared Neighborhood Hits	99
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DDX25_MOUSE
θ value	5.27518 (rank : 125)	NC score	0.024079 (rank : 189)
Query Neighborhood Hits	178	Target Neighborhood Hits	98	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

EXOC2_MOUSE
θ value	5.27518 (rank : 126)	NC score	0.016497 (rank : 208)
Query Neighborhood Hits	178	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D4H1	Gene names	Exoc2, Sec5, Sec5l1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

KIF23_HUMAN
θ value	5.27518 (rank : 127)	NC score	0.026868 (rank : 181)
Query Neighborhood Hits	178	Target Neighborhood Hits	618	Shared Neighborhood Hits	69
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

KINH_HUMAN
θ value	5.27518 (rank : 128)	NC score	0.037626 (rank : 152)
Query Neighborhood Hits	178	Target Neighborhood Hits	1231	Shared Neighborhood Hits	96
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

MACF1_MOUSE
θ value	5.27518 (rank : 129)	NC score	0.039245 (rank : 149)
Query Neighborhood Hits	178	Target Neighborhood Hits	1313	Shared Neighborhood Hits	84
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MAP1A_HUMAN
θ value	5.27518 (rank : 130)	NC score	0.051074 (rank : 110)
Query Neighborhood Hits	178	Target Neighborhood Hits	1626	Shared Neighborhood Hits	104
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MINT_HUMAN
θ value	5.27518 (rank : 131)	NC score	0.031470 (rank : 170)
Query Neighborhood Hits	178	Target Neighborhood Hits	1291	Shared Neighborhood Hits	64
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYO3A_HUMAN
θ value	5.27518 (rank : 132)	NC score	0.003724 (rank : 230)
Query Neighborhood Hits	178	Target Neighborhood Hits	1033	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

MYO5B_HUMAN
θ value	5.27518 (rank : 133)	NC score	0.026143 (rank : 185)
Query Neighborhood Hits	178	Target Neighborhood Hits	911	Shared Neighborhood Hits	85
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

NIN_MOUSE
θ value	5.27518 (rank : 134)	NC score	0.039471 (rank : 147)
Query Neighborhood Hits	178	Target Neighborhood Hits	1376	Shared Neighborhood Hits	98
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

NUP88_HUMAN
θ value	5.27518 (rank : 135)	NC score	0.033916 (rank : 161)
Query Neighborhood Hits	178	Target Neighborhood Hits	354	Shared Neighborhood Hits	56
SwissProt Accessions	Q99567, Q9BWE5	Gene names	NUP88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

RGS2_MOUSE
θ value	5.27518 (rank : 136)	NC score	0.007594 (rank : 221)
Query Neighborhood Hits	178	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	O08849, Q544S7, Q91WX1, Q9JL24	Gene names	Rgs2
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2).

RUFY3_HUMAN
θ value	5.27518 (rank : 137)	NC score	0.026851 (rank : 182)
Query Neighborhood Hits	178	Target Neighborhood Hits	594	Shared Neighborhood Hits	69
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

SETX_HUMAN
θ value	5.27518 (rank : 138)	NC score	0.015311 (rank : 211)
Query Neighborhood Hits	178	Target Neighborhood Hits	368	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

STIM1_MOUSE
θ value	5.27518 (rank : 139)	NC score	0.036225 (rank : 157)
Query Neighborhood Hits	178	Target Neighborhood Hits	660	Shared Neighborhood Hits	73
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

TXLNB_HUMAN
θ value	5.27518 (rank : 140)	NC score	0.035888 (rank : 158)
Query Neighborhood Hits	178	Target Neighborhood Hits	912	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

AMOT_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.032189 (rank : 167)
Query Neighborhood Hits	178	Target Neighborhood Hits	712	Shared Neighborhood Hits	76
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

DDX53_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.006004 (rank : 225)
Query Neighborhood Hits	178	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

DMN_HUMAN
θ value	6.88961 (rank : 143)	NC score	0.016969 (rank : 206)
Query Neighborhood Hits	178	Target Neighborhood Hits	690	Shared Neighborhood Hits	63
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

DUT_HUMAN
θ value	6.88961 (rank : 144)	NC score	0.012718 (rank : 215)
Query Neighborhood Hits	178	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	P33316, O14785, Q16708, Q16860, Q96Q81	Gene names	DUT
Domain Architecture
Description	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial precursor (EC 3.6.1.23) (dUTPase) (dUTP pyrophosphatase).

GRAP1_MOUSE
θ value	6.88961 (rank : 145)	NC score	0.042298 (rank : 135)
Query Neighborhood Hits	178	Target Neighborhood Hits	1234	Shared Neighborhood Hits	97
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

HORN_MOUSE
θ value	6.88961 (rank : 146)	NC score	0.017607 (rank : 204)
Query Neighborhood Hits	178	Target Neighborhood Hits	218	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

MY18A_MOUSE
θ value	6.88961 (rank : 147)	NC score	0.041625 (rank : 139)
Query Neighborhood Hits	178	Target Neighborhood Hits	1989	Shared Neighborhood Hits	110
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

PACN3_MOUSE
θ value	6.88961 (rank : 148)	NC score	0.009429 (rank : 220)
Query Neighborhood Hits	178	Target Neighborhood Hits	380	Shared Neighborhood Hits	28
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

PESC_HUMAN
θ value	6.88961 (rank : 149)	NC score	0.015329 (rank : 210)
Query Neighborhood Hits	178	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	O00541, Q6IC29	Gene names	PES1
Domain Architecture
Description	Pescadillo homolog 1.

PGAM2_MOUSE
θ value	6.88961 (rank : 150)	NC score	0.006800 (rank : 222)
Query Neighborhood Hits	178	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	O70250	Gene names	Pgam2
Domain Architecture
Description	Phosphoglycerate mutase 2 (EC 5.4.2.1) (EC 5.4.2.4) (EC 3.1.3.13) (Phosphoglycerate mutase isozyme M) (PGAM-M) (BPG-dependent PGAM 2) (Muscle-specific phosphoglycerate mutase).

RGS2_HUMAN
θ value	6.88961 (rank : 151)	NC score	0.006715 (rank : 223)
Query Neighborhood Hits	178	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P41220	Gene names	RGS2, G0S8
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2) (G0/G1 switch regulatory protein 8).

SH24A_HUMAN
θ value	6.88961 (rank : 152)	NC score	0.028397 (rank : 178)
Query Neighborhood Hits	178	Target Neighborhood Hits	455	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

STMN2_HUMAN
θ value	6.88961 (rank : 153)	NC score	0.037303 (rank : 153)
Query Neighborhood Hits	178	Target Neighborhood Hits	458	Shared Neighborhood Hits	58
SwissProt Accessions	Q93045, O14952, Q6PK68	Gene names	STMN2, SCG10, SCGN10
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

STMN2_MOUSE
θ value	6.88961 (rank : 154)	NC score	0.037303 (rank : 154)
Query Neighborhood Hits	178	Target Neighborhood Hits	458	Shared Neighborhood Hits	58
SwissProt Accessions	P55821	Gene names	Stmn2, Scg10, Scgn10, Stmb2
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

AMOL1_MOUSE
θ value	8.99809 (rank : 155)	NC score	0.030304 (rank : 174)
Query Neighborhood Hits	178	Target Neighborhood Hits	445	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

CP2A5_MOUSE
θ value	8.99809 (rank : 156)	NC score	0.000766 (rank : 232)
Query Neighborhood Hits	178	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	P20852	Gene names	Cyp2a5, Cyp2a-5
Domain Architecture
Description	Cytochrome P450 2A5 (EC 1.14.14.1) (CYPIIA5) (Coumarin 7-hydroxylase) (P450-15-COH) (P450-IIA3.2).

CTGE5_HUMAN
θ value	8.99809 (rank : 157)	NC score	0.032881 (rank : 164)
Query Neighborhood Hits	178	Target Neighborhood Hits	800	Shared Neighborhood Hits	83
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

EEA1_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.045211 (rank : 126)
Query Neighborhood Hits	178	Target Neighborhood Hits	1796	Shared Neighborhood Hits	107
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

FBN3_HUMAN
θ value	8.99809 (rank : 159)	NC score	-0.002090 (rank : 235)
Query Neighborhood Hits	178	Target Neighborhood Hits	543	Shared Neighborhood Hits	4
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FLIP1_HUMAN
θ value	8.99809 (rank : 160)	NC score	0.042613 (rank : 133)
Query Neighborhood Hits	178	Target Neighborhood Hits	1405	Shared Neighborhood Hits	101
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GOGA4_MOUSE
θ value	8.99809 (rank : 161)	NC score	0.047643 (rank : 120)
Query Neighborhood Hits	178	Target Neighborhood Hits	1939	Shared Neighborhood Hits	111
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

GOGA5_MOUSE
θ value	8.99809 (rank : 162)	NC score	0.046474 (rank : 122)
Query Neighborhood Hits	178	Target Neighborhood Hits	1434	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

K2C1B_HUMAN
θ value	8.99809 (rank : 163)	NC score	0.010250 (rank : 219)
Query Neighborhood Hits	178	Target Neighborhood Hits	542	Shared Neighborhood Hits	58
SwissProt Accessions	Q7Z794, Q7RTS8	Gene names	KRT1B
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b.

MRT4_HUMAN
θ value	8.99809 (rank : 164)	NC score	0.011333 (rank : 217)
Query Neighborhood Hits	178	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKD2, Q96SS6, Q9BPV9	Gene names	MRT4, C1orf33
Domain Architecture	No domain graphic available
Description	mRNA turnover protein 4 homolog.

MYH4_MOUSE
θ value	8.99809 (rank : 165)	NC score	0.032828 (rank : 165)
Query Neighborhood Hits	178	Target Neighborhood Hits	1476	Shared Neighborhood Hits	95
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH8_MOUSE
θ value	8.99809 (rank : 166)	NC score	0.036544 (rank : 156)
Query Neighborhood Hits	178	Target Neighborhood Hits	1600	Shared Neighborhood Hits	105
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NUP88_MOUSE
θ value	8.99809 (rank : 167)	NC score	0.028195 (rank : 180)
Query Neighborhood Hits	178	Target Neighborhood Hits	239	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CEC0, Q80Z13, Q8K090	Gene names	Nup88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

PGAM2_HUMAN
θ value	8.99809 (rank : 168)	NC score	0.006125 (rank : 224)
Query Neighborhood Hits	178	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	P15259	Gene names	PGAM2, PGAMM
Domain Architecture
Description	Phosphoglycerate mutase 2 (EC 5.4.2.1) (EC 5.4.2.4) (EC 3.1.3.13) (Phosphoglycerate mutase isozyme M) (PGAM-M) (BPG-dependent PGAM 2) (Muscle-specific phosphoglycerate mutase).

RGNEF_MOUSE
θ value	8.99809 (rank : 169)	NC score	0.016516 (rank : 207)
Query Neighborhood Hits	178	Target Neighborhood Hits	641	Shared Neighborhood Hits	55
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

RRMJ3_MOUSE
θ value	8.99809 (rank : 170)	NC score	0.019853 (rank : 197)
Query Neighborhood Hits	178	Target Neighborhood Hits	163	Shared Neighborhood Hits	29
SwissProt Accessions	Q9DBE9, Q3ULI1, Q921I7	Gene names	Ftsj3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

SDCG8_HUMAN
θ value	8.99809 (rank : 171)	NC score	0.039263 (rank : 148)
Query Neighborhood Hits	178	Target Neighborhood Hits	1002	Shared Neighborhood Hits	85
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

SFPQ_HUMAN
θ value	8.99809 (rank : 172)	NC score	0.015177 (rank : 212)
Query Neighborhood Hits	178	Target Neighborhood Hits	986	Shared Neighborhood Hits	64
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SFPQ_MOUSE
θ value	8.99809 (rank : 173)	NC score	0.015984 (rank : 209)
Query Neighborhood Hits	178	Target Neighborhood Hits	958	Shared Neighborhood Hits	66
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

STIM1_HUMAN
θ value	8.99809 (rank : 174)	NC score	0.034687 (rank : 160)
Query Neighborhood Hits	178	Target Neighborhood Hits	665	Shared Neighborhood Hits	72
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

STK10_MOUSE
θ value	8.99809 (rank : 175)	NC score	0.026226 (rank : 184)
Query Neighborhood Hits	178	Target Neighborhood Hits	2132	Shared Neighborhood Hits	109
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TRIM8_HUMAN
θ value	8.99809 (rank : 176)	NC score	0.011850 (rank : 216)
Query Neighborhood Hits	178	Target Neighborhood Hits	650	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

ULK2_HUMAN
θ value	8.99809 (rank : 177)	NC score	-0.000810 (rank : 234)
Query Neighborhood Hits	178	Target Neighborhood Hits	979	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

ZN263_HUMAN
θ value	8.99809 (rank : 178)	NC score	-0.005553 (rank : 236)
Query Neighborhood Hits	178	Target Neighborhood Hits	795	Shared Neighborhood Hits	6
SwissProt Accessions	O14978, O43387, Q96H95	Gene names	ZNF263, FPM315
Domain Architecture
Description	Zinc finger protein 263 (Zinc finger protein FPM315).

AIRE_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.088863 (rank : 40)
Query Neighborhood Hits	178	Target Neighborhood Hits	144	Shared Neighborhood Hits	6
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

AIRE_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.090404 (rank : 39)
Query Neighborhood Hits	178	Target Neighborhood Hits	196	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

BAZ1A_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.086839 (rank : 41)
Query Neighborhood Hits	178	Target Neighborhood Hits	693	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

BAZ1B_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.073155 (rank : 54)
Query Neighborhood Hits	178	Target Neighborhood Hits	701	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ1B_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.076909 (rank : 51)
Query Neighborhood Hits	178	Target Neighborhood Hits	394	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

BAZ2A_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.058896 (rank : 76)
Query Neighborhood Hits	178	Target Neighborhood Hits	780	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

BAZ2A_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.054155 (rank : 96)
Query Neighborhood Hits	178	Target Neighborhood Hits	744	Shared Neighborhood Hits	57
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

BAZ2B_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.072302 (rank : 55)
Query Neighborhood Hits	178	Target Neighborhood Hits	803	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BPTF_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.091831 (rank : 38)
Query Neighborhood Hits	178	Target Neighborhood Hits	786	Shared Neighborhood Hits	55
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

CBX1_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.061015 (rank : 73)
Query Neighborhood Hits	178	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.061015 (rank : 74)
Query Neighborhood Hits	178	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX3_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.053498 (rank : 101)
Query Neighborhood Hits	178	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX3_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.056269 (rank : 87)
Query Neighborhood Hits	178	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CBX5_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.075004 (rank : 53)
Query Neighborhood Hits	178	Target Neighborhood Hits	70	Shared Neighborhood Hits	13
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.066894 (rank : 62)
Query Neighborhood Hits	178	Target Neighborhood Hits	67	Shared Neighborhood Hits	12
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CBX7_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.053822 (rank : 98)
Query Neighborhood Hits	178	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

CBX7_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.056940 (rank : 85)
Query Neighborhood Hits	178	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

CI039_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.050269 (rank : 114)
Query Neighborhood Hits	178	Target Neighborhood Hits	1171	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

HIRP3_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.056598 (rank : 86)
Query Neighborhood Hits	178	Target Neighborhood Hits	323	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

IWS1_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.067236 (rank : 61)
Query Neighborhood Hits	178	Target Neighborhood Hits	1241	Shared Neighborhood Hits	60
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

IWS1_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.071134 (rank : 56)
Query Neighborhood Hits	178	Target Neighborhood Hits	1258	Shared Neighborhood Hits	51
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

LEO1_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.061654 (rank : 71)
Query Neighborhood Hits	178	Target Neighborhood Hits	958	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LEO1_MOUSE
θ value	θ > 10 (rank : 201)	NC score	0.063099 (rank : 67)
Query Neighborhood Hits	178	Target Neighborhood Hits	946	Shared Neighborhood Hits	39
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

LY10_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.061940 (rank : 70)
Query Neighborhood Hits	178	Target Neighborhood Hits	151	Shared Neighborhood Hits	8
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

MLL2_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.051207 (rank : 109)
Query Neighborhood Hits	178	Target Neighborhood Hits	1788	Shared Neighborhood Hits	75
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.052568 (rank : 104)
Query Neighborhood Hits	178	Target Neighborhood Hits	1644	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MPP8_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.057044 (rank : 84)
Query Neighborhood Hits	178	Target Neighborhood Hits	948	Shared Neighborhood Hits	82
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

NIPBL_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.066777 (rank : 63)
Query Neighborhood Hits	178	Target Neighborhood Hits	1311	Shared Neighborhood Hits	77
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.057791 (rank : 80)
Query Neighborhood Hits	178	Target Neighborhood Hits	1041	Shared Neighborhood Hits	55
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

NSD1_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.054442 (rank : 92)
Query Neighborhood Hits	178	Target Neighborhood Hits	427	Shared Neighborhood Hits	10
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.057228 (rank : 83)
Query Neighborhood Hits	178	Target Neighborhood Hits	472	Shared Neighborhood Hits	15
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

PB1_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.054312 (rank : 95)
Query Neighborhood Hits	178	Target Neighborhood Hits	261	Shared Neighborhood Hits	6
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

PF21A_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.077640 (rank : 50)
Query Neighborhood Hits	178	Target Neighborhood Hits	303	Shared Neighborhood Hits	24
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

PF21A_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.078970 (rank : 47)
Query Neighborhood Hits	178	Target Neighborhood Hits	285	Shared Neighborhood Hits	29
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

PF21B_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.077911 (rank : 49)
Query Neighborhood Hits	178	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21B_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.079154 (rank : 45)
Query Neighborhood Hits	178	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PHF12_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.084645 (rank : 43)
Query Neighborhood Hits	178	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_MOUSE
θ value	θ > 10 (rank : 216)	NC score	0.084807 (rank : 42)
Query Neighborhood Hits	178	Target Neighborhood Hits	172	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF20_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.052392 (rank : 106)
Query Neighborhood Hits	178	Target Neighborhood Hits	513	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

PKCB1_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.080843 (rank : 44)
Query Neighborhood Hits	178	Target Neighborhood Hits	488	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

RBBP6_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.058380 (rank : 78)
Query Neighborhood Hits	178	Target Neighborhood Hits	1135	Shared Neighborhood Hits	55
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.058044 (rank : 79)
Query Neighborhood Hits	178	Target Neighborhood Hits	1014	Shared Neighborhood Hits	50
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

RBM25_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.059674 (rank : 75)
Query Neighborhood Hits	178	Target Neighborhood Hits	682	Shared Neighborhood Hits	92
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

RRBP1_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.050641 (rank : 113)
Query Neighborhood Hits	178	Target Neighborhood Hits	1650	Shared Neighborhood Hits	104
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

RSF1_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.079104 (rank : 46)
Query Neighborhood Hits	178	Target Neighborhood Hits	539	Shared Neighborhood Hits	61
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SMC1A_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.052825 (rank : 103)
Query Neighborhood Hits	178	Target Neighborhood Hits	1384	Shared Neighborhood Hits	107
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SP110_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.068975 (rank : 58)
Query Neighborhood Hits	178	Target Neighborhood Hits	141	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TCAL5_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.052470 (rank : 105)
Query Neighborhood Hits	178	Target Neighborhood Hits	806	Shared Neighborhood Hits	33
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TGON2_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.065825 (rank : 64)
Query Neighborhood Hits	178	Target Neighborhood Hits	1037	Shared Neighborhood Hits	34
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TIF1A_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.062413 (rank : 68)
Query Neighborhood Hits	178	Target Neighborhood Hits	327	Shared Neighborhood Hits	20
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

TIF1A_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.064632 (rank : 66)
Query Neighborhood Hits	178	Target Neighborhood Hits	307	Shared Neighborhood Hits	15
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

TIF1G_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.057448 (rank : 82)
Query Neighborhood Hits	178	Target Neighborhood Hits	410	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

TIF1G_MOUSE
θ value	θ > 10 (rank : 231)	NC score	0.064847 (rank : 65)
Query Neighborhood Hits	178	Target Neighborhood Hits	498	Shared Neighborhood Hits	27
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TRI66_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.069575 (rank : 57)
Query Neighborhood Hits	178	Target Neighborhood Hits	479	Shared Neighborhood Hits	28
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TRI66_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.068511 (rank : 59)
Query Neighborhood Hits	178	Target Neighborhood Hits	491	Shared Neighborhood Hits	30
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

TXND2_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.061347 (rank : 72)
Query Neighborhood Hits	178	Target Neighborhood Hits	828	Shared Neighborhood Hits	55
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

ZMY11_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.077972 (rank : 48)
Query Neighborhood Hits	178	Target Neighborhood Hits	201	Shared Neighborhood Hits	21
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

ZMY11_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.076085 (rank : 52)
Query Neighborhood Hits	178	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

Hits sorted by NC score

INOC1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	178	Target Neighborhood Hits	178	Shared Neighborhood Hits	178
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

INOC1_HUMAN
NC score	0.996826 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	178	Target Neighborhood Hits	181	Shared Neighborhood Hits	149
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

SMCA1_HUMAN
NC score	0.920806 (rank : 3)	θ value	1.5555e-68 (rank : 3)
Query Neighborhood Hits	178	Target Neighborhood Hits	105	Shared Neighborhood Hits	43
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA5_HUMAN
NC score	0.920715 (rank : 4)	θ value	7.2256e-66 (rank : 7)
Query Neighborhood Hits	178	Target Neighborhood Hits	76	Shared Neighborhood Hits	41
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA5_MOUSE
NC score	0.920522 (rank : 5)	θ value	1.6097e-65 (rank : 8)
Query Neighborhood Hits	178	Target Neighborhood Hits	80	Shared Neighborhood Hits	41
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMRCD_HUMAN
NC score	0.920096 (rank : 6)	θ value	1.45929e-58 (rank : 10)
Query Neighborhood Hits	178	Target Neighborhood Hits	117	Shared Neighborhood Hits	46
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

SMRCD_MOUSE
NC score	0.919634 (rank : 7)	θ value	1.36585e-56 (rank : 11)
Query Neighborhood Hits	178	Target Neighborhood Hits	96	Shared Neighborhood Hits	41
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

SMCA1_MOUSE
NC score	0.917968 (rank : 8)	θ value	7.71989e-68 (rank : 5)
Query Neighborhood Hits	178	Target Neighborhood Hits	117	Shared Neighborhood Hits	44
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

BTAF1_HUMAN
NC score	0.899749 (rank : 9)	θ value	1.05066e-40 (rank : 24)
Query Neighborhood Hits	178	Target Neighborhood Hits	97	Shared Neighborhood Hits	39
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

CHD2_HUMAN
NC score	0.894422 (rank : 10)	θ value	3.84025e-59 (rank : 9)
Query Neighborhood Hits	178	Target Neighborhood Hits	360	Shared Neighborhood Hits	67
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

ERCC6_HUMAN
NC score	0.890484 (rank : 11)	θ value	7.79185e-36 (rank : 25)
Query Neighborhood Hits	178	Target Neighborhood Hits	247	Shared Neighborhood Hits	52
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

CHD1_MOUSE
NC score	0.890328 (rank : 12)	θ value	6.77864e-56 (rank : 13)
Query Neighborhood Hits	178	Target Neighborhood Hits	266	Shared Neighborhood Hits	47
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_HUMAN
NC score	0.886752 (rank : 13)	θ value	3.974e-56 (rank : 12)
Query Neighborhood Hits	178	Target Neighborhood Hits	337	Shared Neighborhood Hits	52
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD8_HUMAN
NC score	0.885483 (rank : 14)	θ value	8.02596e-49 (rank : 21)
Query Neighborhood Hits	178	Target Neighborhood Hits	235	Shared Neighborhood Hits	47
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD6_HUMAN
NC score	0.878757 (rank : 15)	θ value	8.02596e-49 (rank : 20)
Query Neighborhood Hits	178	Target Neighborhood Hits	342	Shared Neighborhood Hits	50
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

SMCA2_HUMAN
NC score	0.878726 (rank : 16)	θ value	1.11475e-66 (rank : 6)
Query Neighborhood Hits	178	Target Neighborhood Hits	503	Shared Neighborhood Hits	72
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

RA54B_HUMAN
NC score	0.874889 (rank : 17)	θ value	2.68423e-28 (rank : 26)
Query Neighborhood Hits	178	Target Neighborhood Hits	54	Shared Neighborhood Hits	37
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

CHD9_HUMAN
NC score	0.874174 (rank : 18)	θ value	1.97686e-47 (rank : 22)
Query Neighborhood Hits	178	Target Neighborhood Hits	343	Shared Neighborhood Hits	54
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

RAD54_HUMAN
NC score	0.872133 (rank : 19)	θ value	1.92365e-26 (rank : 28)
Query Neighborhood Hits	178	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RAD54_MOUSE
NC score	0.871698 (rank : 20)	θ value	2.51237e-26 (rank : 29)
Query Neighborhood Hits	178	Target Neighborhood Hits	51	Shared Neighborhood Hits	37
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

RA54B_MOUSE
NC score	0.871223 (rank : 21)	θ value	1.92365e-26 (rank : 27)
Query Neighborhood Hits	178	Target Neighborhood Hits	59	Shared Neighborhood Hits	37
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

CHD9_MOUSE
NC score	0.869791 (rank : 22)	θ value	4.40402e-47 (rank : 23)
Query Neighborhood Hits	178	Target Neighborhood Hits	427	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

SMCA4_HUMAN
NC score	0.869011 (rank : 23)	θ value	2.03155e-68 (rank : 4)
Query Neighborhood Hits	178	Target Neighborhood Hits	597	Shared Neighborhood Hits	78
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

EP400_HUMAN
NC score	0.839559 (rank : 24)	θ value	8.85319e-56 (rank : 14)
Query Neighborhood Hits	178	Target Neighborhood Hits	556	Shared Neighborhood Hits	46
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EP400_MOUSE
NC score	0.832850 (rank : 25)	θ value	1.15626e-55 (rank : 15)
Query Neighborhood Hits	178	Target Neighborhood Hits	592	Shared Neighborhood Hits	49
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

TTF2_HUMAN
NC score	0.827995 (rank : 26)	θ value	3.39556e-23 (rank : 32)
Query Neighborhood Hits	178	Target Neighborhood Hits	98	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

CHD3_HUMAN
NC score	0.826167 (rank : 27)	θ value	7.75577e-52 (rank : 16)
Query Neighborhood Hits	178	Target Neighborhood Hits	397	Shared Neighborhood Hits	47
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_HUMAN
NC score	0.824325 (rank : 28)	θ value	1.61718e-49 (rank : 18)
Query Neighborhood Hits	178	Target Neighborhood Hits	365	Shared Neighborhood Hits	53
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD5_HUMAN
NC score	0.823742 (rank : 29)	θ value	1.72781e-51 (rank : 17)
Query Neighborhood Hits	178	Target Neighborhood Hits	349	Shared Neighborhood Hits	52
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

CHD4_MOUSE
NC score	0.820607 (rank : 30)	θ value	1.61718e-49 (rank : 19)
Query Neighborhood Hits	178	Target Neighborhood Hits	408	Shared Neighborhood Hits	56
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

SMAL1_MOUSE
NC score	0.792551 (rank : 31)	θ value	2.60593e-15 (rank : 37)
Query Neighborhood Hits	178	Target Neighborhood Hits	157	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

TTF2_MOUSE
NC score	0.791640 (rank : 32)	θ value	8.93572e-24 (rank : 30)
Query Neighborhood Hits	178	Target Neighborhood Hits	364	Shared Neighborhood Hits	52
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

SMAL1_HUMAN
NC score	0.787719 (rank : 33)	θ value	6.20254e-17 (rank : 36)
Query Neighborhood Hits	178	Target Neighborhood Hits	174	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZC9, Q96AY1, Q9NXQ5, Q9UFH3, Q9UI93	Gene names	SMARCAL1, HARP
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (hHARP).

SMRA3_MOUSE
NC score	0.714470 (rank : 34)	θ value	1.13037e-18 (rank : 35)
Query Neighborhood Hits	178	Target Neighborhood Hits	267	Shared Neighborhood Hits	40
SwissProt Accessions	Q6PCN7, O35596, O35597, Q80VT6	Gene names	Smarca3, Snf2l3, Zbu1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (TNF-response element-binding protein) (P113).

SMRA3_HUMAN
NC score	0.713568 (rank : 35)	θ value	3.88503e-19 (rank : 34)
Query Neighborhood Hits	178	Target Neighborhood Hits	265	Shared Neighborhood Hits	38
SwissProt Accessions	Q14527, Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9	Gene names	SMARCA3, HIP116A, HLTF, SNF2L3, ZBU1
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 3) (DNA-binding protein/plasminogen activator inhibitor 1 regulator) (Helicase-like transcription factor) (HIP116).

ATRX_MOUSE
NC score	0.691255 (rank : 36)	θ value	3.39556e-23 (rank : 31)
Query Neighborhood Hits	178	Target Neighborhood Hits	682	Shared Neighborhood Hits	92
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

ATRX_HUMAN
NC score	0.680342 (rank : 37)	θ value	4.43474e-23 (rank : 33)
Query Neighborhood Hits	178	Target Neighborhood Hits	842	Shared Neighborhood Hits	115
SwissProt Accessions	P46100, P51068, Q15886, Q59FB5, Q59H31, Q5H9A2, Q5JWI4, Q7Z2J1, Q9H0Z1, Q9NTS3	Gene names	ATRX, RAD54L, XH2
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked helicase II) (X-linked nuclear protein) (XNP) (Znf- HX).

BPTF_HUMAN
NC score	0.091831 (rank : 38)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	178	Target Neighborhood Hits	786	Shared Neighborhood Hits	55
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

AIRE_MOUSE
NC score	0.090404 (rank : 39)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	178	Target Neighborhood Hits	196	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z0E3, Q9JLW0, Q9JLW1, Q9JLW2, Q9JLW3, Q9JLW4, Q9JLW5, Q9JLW6, Q9JLW7, Q9JLW8, Q9JLW9, Q9JLX0	Gene names	Aire
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog).

AIRE_HUMAN
NC score	0.088863 (rank : 40)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	178	Target Neighborhood Hits	144	Shared Neighborhood Hits	6
SwissProt Accessions	O43918, O43922, O43932, O75745	Gene names	AIRE, APECED
Domain Architecture
Description	Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein).

BAZ1A_HUMAN
NC score	0.086839 (rank : 41)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	178	Target Neighborhood Hits	693	Shared Neighborhood Hits	88
SwissProt Accessions	Q9NRL2, Q9NZ15, Q9P065, Q9UIG1, Q9Y3V3	Gene names	BAZ1A, ACF1, WCRF180
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1A (ATP-utilizing chromatin assembly and remodeling factor 1) (hACF1) (ATP-dependent chromatin remodelling protein) (Williams syndrome transcription factor-related chromatin remodeling factor 180) (WCRF180) (hWALp1) (CHRAC subunit ACF1).

PHF12_MOUSE
NC score	0.084807 (rank : 42)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	178	Target Neighborhood Hits	172	Shared Neighborhood Hits	8
SwissProt Accessions	Q5SPL2, Q5SPL3, Q6ZPN8, Q80W50	Gene names	Phf12, Kiaa1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PHF12_HUMAN
NC score	0.084645 (rank : 43)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	178	Target Neighborhood Hits	174	Shared Neighborhood Hits	7
SwissProt Accessions	Q96QT6, Q6ZML2, Q9BV34, Q9H7U9, Q9P205	Gene names	PHF12, KIAA1523
Domain Architecture	No domain graphic available
Description	PHD finger protein 12 (PHD factor 1) (Pf1).

PKCB1_HUMAN
NC score	0.080843 (rank : 44)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	178	Target Neighborhood Hits	488	Shared Neighborhood Hits	31
SwissProt Accessions	Q9ULU4, Q13517, Q4JJ94, Q4JJ95, Q5TH09, Q6MZM1, Q8WXC5, Q9H1F3, Q9H1F4, Q9H1F5, Q9H1L8, Q9H1L9, Q9H2G5, Q9NYN3, Q9UIX6	Gene names	PRKCBP1, KIAA1125, RACK7, ZMYND8
Domain Architecture
Description	Protein kinase C-binding protein 1 (Rack7) (Cutaneous T-cell lymphoma- associated antigen se14-3) (CTCL tumor antigen se14-3) (Zinc finger MYND domain-containing protein 8).

PF21B_MOUSE
NC score	0.079154 (rank : 45)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	178	Target Neighborhood Hits	278	Shared Neighborhood Hits	11
SwissProt Accessions	Q8C966	Gene names	Phf21b
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

RSF1_HUMAN
NC score	0.079104 (rank : 46)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	178	Target Neighborhood Hits	539	Shared Neighborhood Hits	61
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

PF21A_MOUSE
NC score	0.078970 (rank : 47)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	178	Target Neighborhood Hits	285	Shared Neighborhood Hits	29
SwissProt Accessions	Q6ZPK0, Q6XVG0, Q80Z33, Q8CAZ4, Q8VEC8	Gene names	Phf21a, Bhc80, Kiaa1696, Pftf1
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (mBHC80) (BHC80a).

ZMY11_HUMAN
NC score	0.077972 (rank : 48)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	178	Target Neighborhood Hits	201	Shared Neighborhood Hits	21
SwissProt Accessions	Q15326	Gene names	ZMYND11, BS69
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11 (Adenovirus 5 E1A- binding protein) (BS69 protein).

PF21B_HUMAN
NC score	0.077911 (rank : 49)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	178	Target Neighborhood Hits	197	Shared Neighborhood Hits	12
SwissProt Accessions	Q96EK2, Q5TFL2, Q6ICC0	Gene names	PHF21B
Domain Architecture	No domain graphic available
Description	PHD finger protein 21B.

PF21A_HUMAN
NC score	0.077640 (rank : 50)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	178	Target Neighborhood Hits	303	Shared Neighborhood Hits	24
SwissProt Accessions	Q96BD5, Q6AWA2, Q9C0G7, Q9H8V9, Q9HAK6, Q9NZE9	Gene names	PHF21A, BHC80, KIAA1696
Domain Architecture	No domain graphic available
Description	PHD finger protein 21A (BRAF35-HDAC complex protein BHC80) (BHC80a).

BAZ1B_MOUSE
NC score	0.076909 (rank : 51)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	178	Target Neighborhood Hits	394	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Z277, Q9CU68	Gene names	Baz1b, Wbscr9
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein homolog) (WBRS9).

ZMY11_MOUSE
NC score	0.076085 (rank : 52)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	178	Target Neighborhood Hits	198	Shared Neighborhood Hits	21
SwissProt Accessions	Q8R5C8, Q8C155	Gene names	Zmynd11
Domain Architecture
Description	Zinc finger MYND domain-containing protein 11.

CBX5_HUMAN
NC score	0.075004 (rank : 53)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	178	Target Neighborhood Hits	70	Shared Neighborhood Hits	13
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

BAZ1B_HUMAN
NC score	0.073155 (rank : 54)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	178	Target Neighborhood Hits	701	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UIG0, O95039, O95247, O95277	Gene names	BAZ1B, WBSC10, WBSCR9, WSTF
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain protein 1B (Williams-Beuren syndrome chromosome region 9 protein) (Williams syndrome transcription factor) (hWALP2).

BAZ2B_HUMAN
NC score	0.072302 (rank : 55)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	178	Target Neighborhood Hits	803	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

IWS1_MOUSE
NC score	0.071134 (rank : 56)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	178	Target Neighborhood Hits	1258	Shared Neighborhood Hits	51
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TRI66_HUMAN
NC score	0.069575 (rank : 57)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	178	Target Neighborhood Hits	479	Shared Neighborhood Hits	28
SwissProt Accessions	O15016, Q9BQQ4	Gene names	TRIM66, KIAA0298
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

SP110_HUMAN
NC score	0.068975 (rank : 58)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	178	Target Neighborhood Hits	141	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HB58, Q14976, Q14977, Q8WUZ6, Q9HCT8	Gene names	SP110
Domain Architecture
Description	Sp110 nuclear body protein (Speckled 110 kDa) (Transcriptional coactivator Sp110) (Interferon-induced protein 41/75).

TRI66_MOUSE
NC score	0.068511 (rank : 59)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	178	Target Neighborhood Hits	491	Shared Neighborhood Hits	30
SwissProt Accessions	Q924W6	Gene names	Trim66
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 66.

CCD91_HUMAN
NC score	0.068467 (rank : 60)	θ value	0.0193708 (rank : 41)
Query Neighborhood Hits	178	Target Neighborhood Hits	868	Shared Neighborhood Hits	89
SwissProt Accessions	Q7Z6B0, Q68D43, Q6IA78, Q8NEN7, Q9NUW9	Gene names	CCDC91, GGABP
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 91 (GGA-binding partner) (p56 accessory protein).

IWS1_HUMAN
NC score	0.067236 (rank : 61)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	178	Target Neighborhood Hits	1241	Shared Neighborhood Hits	60
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

CBX5_MOUSE
NC score	0.066894 (rank : 62)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	178	Target Neighborhood Hits	67	Shared Neighborhood Hits	12
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

NIPBL_HUMAN
NC score	0.066777 (rank : 63)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	178	Target Neighborhood Hits	1311	Shared Neighborhood Hits	77
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

TGON2_HUMAN
NC score	0.065825 (rank : 64)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	178	Target Neighborhood Hits	1037	Shared Neighborhood Hits	34
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

TIF1G_MOUSE
NC score	0.064847 (rank : 65)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	178	Target Neighborhood Hits	498	Shared Neighborhood Hits	27
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TIF1A_MOUSE
NC score	0.064632 (rank : 66)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	178	Target Neighborhood Hits	307	Shared Neighborhood Hits	15
SwissProt Accessions	Q64127, Q64126	Gene names	Trim24, Tif1, Tif1a
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24).

LEO1_MOUSE
NC score	0.063099 (rank : 67)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	178	Target Neighborhood Hits	946	Shared Neighborhood Hits	39
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

TIF1A_HUMAN
NC score	0.062413 (rank : 68)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	178	Target Neighborhood Hits	327	Shared Neighborhood Hits	20
SwissProt Accessions	O15164, O95854	Gene names	TRIM24, RNF82, TIF1, TIF1A
Domain Architecture
Description	Transcription intermediary factor 1-alpha (TIF1-alpha) (Tripartite motif-containing protein 24) (RING finger protein 82).

SEMG2_HUMAN
NC score	0.061968 (rank : 69)	θ value	0.0330416 (rank : 47)
Query Neighborhood Hits	178	Target Neighborhood Hits	251	Shared Neighborhood Hits	25
SwissProt Accessions	Q02383, Q6X2M6	Gene names	SEMG2
Domain Architecture
Description	Semenogelin-2 precursor (Semenogelin II) (SGII).

LY10_HUMAN
NC score	0.061940 (rank : 70)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	178	Target Neighborhood Hits	151	Shared Neighborhood Hits	8
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

LEO1_HUMAN
NC score	0.061654 (rank : 71)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	178	Target Neighborhood Hits	958	Shared Neighborhood Hits	39
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

TXND2_MOUSE
NC score	0.061347 (rank : 72)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	178	Target Neighborhood Hits	828	Shared Neighborhood Hits	55
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

CBX1_HUMAN
NC score	0.061015 (rank : 73)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	178	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.061015 (rank : 74)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	178	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

RBM25_HUMAN
NC score	0.059674 (rank : 75)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	178	Target Neighborhood Hits	682	Shared Neighborhood Hits	92
SwissProt Accessions	P49756, Q9UEQ5, Q9UIE9	Gene names	RBM25, RNPC7
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 25 (RNA-binding motif protein 25) (RNA- binding region-containing protein 7) (Protein S164).

BAZ2A_HUMAN
NC score	0.058896 (rank : 76)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	178	Target Neighborhood Hits	780	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CT2NL_HUMAN
NC score	0.058397 (rank : 77)	θ value	0.163984 (rank : 53)
Query Neighborhood Hits	178	Target Neighborhood Hits	1059	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

RBBP6_HUMAN
NC score	0.058380 (rank : 78)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	178	Target Neighborhood Hits	1135	Shared Neighborhood Hits	55
SwissProt Accessions	Q7Z6E9, Q15290, Q6DKH4, Q6P4C2, Q6YNC9, Q7Z6E8, Q8N0V2, Q96PH3, Q9H3I8, Q9H5M5, Q9NPX4	Gene names	RBBP6, P2PR, PACT, RBQ1
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (Protein RBQ-1).

RBBP6_MOUSE
NC score	0.058044 (rank : 79)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	178	Target Neighborhood Hits	1014	Shared Neighborhood Hits	50
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

NPBL_MOUSE
NC score	0.057791 (rank : 80)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	178	Target Neighborhood Hits	1041	Shared Neighborhood Hits	55
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

SM1L2_HUMAN
NC score	0.057755 (rank : 81)	θ value	0.0961366 (rank : 49)
Query Neighborhood Hits	178	Target Neighborhood Hits	1019	Shared Neighborhood Hits	91
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

TIF1G_HUMAN
NC score	0.057448 (rank : 82)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	178	Target Neighborhood Hits	410	Shared Neighborhood Hits	19
SwissProt Accessions	Q9UPN9, O95855, Q9C017, Q9UJ79	Gene names	TRIM33, KIAA1113, RFG7, TIF1G
Domain Architecture
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33) (RET-fused gene 7 protein) (Rfg7 protein).

NSD1_MOUSE
NC score	0.057228 (rank : 83)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	178	Target Neighborhood Hits	472	Shared Neighborhood Hits	15
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

MPP8_HUMAN
NC score	0.057044 (rank : 84)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	178	Target Neighborhood Hits	948	Shared Neighborhood Hits	82
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

CBX7_MOUSE
NC score	0.056940 (rank : 85)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	178	Target Neighborhood Hits	38	Shared Neighborhood Hits	8
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

HIRP3_HUMAN
NC score	0.056598 (rank : 86)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	178	Target Neighborhood Hits	323	Shared Neighborhood Hits	44
SwissProt Accessions	Q9BW71, O75707, O75708	Gene names	HIRIP3
Domain Architecture	No domain graphic available
Description	HIRA-interacting protein 3.

CBX3_MOUSE
NC score	0.056269 (rank : 87)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	178	Target Neighborhood Hits	39	Shared Neighborhood Hits	10
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

BPAEA_MOUSE
NC score	0.055839 (rank : 88)	θ value	0.0113563 (rank : 39)
Query Neighborhood Hits	178	Target Neighborhood Hits	1480	Shared Neighborhood Hits	97
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CJ118_MOUSE
NC score	0.055490 (rank : 89)	θ value	0.0252991 (rank : 43)
Query Neighborhood Hits	178	Target Neighborhood Hits	1132	Shared Neighborhood Hits	90
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

SKIL_MOUSE
NC score	0.055412 (rank : 90)	θ value	0.163984 (rank : 55)
Query Neighborhood Hits	178	Target Neighborhood Hits	719	Shared Neighborhood Hits	80
SwissProt Accessions	Q60665, Q60702, Q78E90, Q80VK5	Gene names	Skil, Skir, Sno
Domain Architecture
Description	Ski-like protein (Ski-related protein) (Ski-related oncogene).

CEP35_HUMAN
NC score	0.054804 (rank : 91)	θ value	0.813845 (rank : 73)
Query Neighborhood Hits	178	Target Neighborhood Hits	811	Shared Neighborhood Hits	77
SwissProt Accessions	Q5VT06, O75068, Q8TDK3, Q8WY20	Gene names	CEP350, CAP350, GM133
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein 350 (Centrosome-associated protein of 350 kDa).

NSD1_HUMAN
NC score	0.054442 (rank : 92)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	178	Target Neighborhood Hits	427	Shared Neighborhood Hits	10
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

SMC2_MOUSE
NC score	0.054439 (rank : 93)	θ value	1.38821 (rank : 86)
Query Neighborhood Hits	178	Target Neighborhood Hits	1131	Shared Neighborhood Hits	90
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

SMC2_HUMAN
NC score	0.054420 (rank : 94)	θ value	4.03905 (rank : 120)
Query Neighborhood Hits	178	Target Neighborhood Hits	1405	Shared Neighborhood Hits	103
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

PB1_HUMAN
NC score	0.054312 (rank : 95)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	178	Target Neighborhood Hits	261	Shared Neighborhood Hits	6
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

BAZ2A_MOUSE
NC score	0.054155 (rank : 96)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	178	Target Neighborhood Hits	744	Shared Neighborhood Hits	57
SwissProt Accessions	Q91YE5	Gene names	Baz2a, Tip5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5).

CT2NL_MOUSE
NC score	0.054073 (rank : 97)	θ value	0.21417 (rank : 57)
Query Neighborhood Hits	178	Target Neighborhood Hits	902	Shared Neighborhood Hits	85
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CBX7_HUMAN
NC score	0.053822 (rank : 98)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	178	Target Neighborhood Hits	48	Shared Neighborhood Hits	8
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

SMC3_HUMAN
NC score	0.053650 (rank : 99)	θ value	1.06291 (rank : 76)
Query Neighborhood Hits	178	Target Neighborhood Hits	1186	Shared Neighborhood Hits	97
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
NC score	0.053518 (rank : 100)	θ value	1.06291 (rank : 77)
Query Neighborhood Hits	178	Target Neighborhood Hits	1187	Shared Neighborhood Hits	97
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

CBX3_HUMAN
NC score	0.053498 (rank : 101)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	178	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

DDX41_MOUSE
NC score	0.053181 (rank : 102)	θ value	0.365318 (rank : 61)
Query Neighborhood Hits	178	Target Neighborhood Hits	115	Shared Neighborhood Hits	22
SwissProt Accessions	Q91VN6	Gene names	Ddx41
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41).

SMC1A_MOUSE
NC score	0.052825 (rank : 103)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	178	Target Neighborhood Hits	1384	Shared Neighborhood Hits	107
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

MLL3_HUMAN
NC score	0.052568 (rank : 104)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	178	Target Neighborhood Hits	1644	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

TCAL5_HUMAN
NC score	0.052470 (rank : 105)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	178	Target Neighborhood Hits	806	Shared Neighborhood Hits	33
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

PHF20_MOUSE
NC score	0.052392 (rank : 106)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	178	Target Neighborhood Hits	513	Shared Neighborhood Hits	35
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

GOGB1_HUMAN
NC score	0.052347 (rank : 107)	θ value	1.38821 (rank : 82)
Query Neighborhood Hits	178	Target Neighborhood Hits	2297	Shared Neighborhood Hits	118
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

EEA1_MOUSE
NC score	0.052253 (rank : 108)	θ value	0.0252991 (rank : 44)
Query Neighborhood Hits	178	Target Neighborhood Hits	1637	Shared Neighborhood Hits	107
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

MLL2_HUMAN
NC score	0.051207 (rank : 109)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	178	Target Neighborhood Hits	1788	Shared Neighborhood Hits	75
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MAP1A_HUMAN
NC score	0.051074 (rank : 110)	θ value	5.27518 (rank : 130)
Query Neighborhood Hits	178	Target Neighborhood Hits	1626	Shared Neighborhood Hits	104
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

GCC2_HUMAN
NC score	0.050989 (rank : 111)	θ value	0.125558 (rank : 50)
Query Neighborhood Hits	178	Target Neighborhood Hits	1558	Shared Neighborhood Hits	101
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
NC score	0.050649 (rank : 112)	θ value	0.125558 (rank : 51)
Query Neighborhood Hits	178	Target Neighborhood Hits	1559	Shared Neighborhood Hits	101
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

RRBP1_MOUSE
NC score	0.050641 (rank : 113)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	178	Target Neighborhood Hits	1650	Shared Neighborhood Hits	104
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

CI039_HUMAN
NC score	0.050269 (rank : 114)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	178	Target Neighborhood Hits	1171	Shared Neighborhood Hits	95
SwissProt Accessions	Q9NXG0, Q5VYJ0, Q9HAJ5	Gene names	C9orf39
Domain Architecture	No domain graphic available
Description	Protein C9orf39.

CENPE_HUMAN
NC score	0.050049 (rank : 115)	θ value	0.47712 (rank : 63)
Query Neighborhood Hits	178	Target Neighborhood Hits	2060	Shared Neighborhood Hits	111
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

DDX41_HUMAN
NC score	0.049991 (rank : 116)	θ value	0.365318 (rank : 60)
Query Neighborhood Hits	178	Target Neighborhood Hits	111	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UJV9, Q96BK6, Q96K05, Q9NT96, Q9NW04	Gene names	DDX41, ABS
Domain Architecture
Description	Probable ATP-dependent RNA helicase DDX41 (EC 3.6.1.-) (DEAD box protein 41) (DEAD box protein abstrakt homolog).

ANR26_MOUSE
NC score	0.049805 (rank : 117)	θ value	0.00298849 (rank : 38)
Query Neighborhood Hits	178	Target Neighborhood Hits	1554	Shared Neighborhood Hits	101
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

ANR26_HUMAN
NC score	0.049741 (rank : 118)	θ value	0.21417 (rank : 56)
Query Neighborhood Hits	178	Target Neighborhood Hits	1614	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UPS8, Q2TAZ3, Q6ZR14, Q9H1Q1, Q9NSK9, Q9NTD5, Q9NW69	Gene names	ANKRD26, KIAA1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

DESP_HUMAN
NC score	0.048032 (rank : 119)	θ value	0.62314 (rank : 69)
Query Neighborhood Hits	178	Target Neighborhood Hits	1470	Shared Neighborhood Hits	101
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

GOGA4_MOUSE
NC score	0.047643 (rank : 120)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	178	Target Neighborhood Hits	1939	Shared Neighborhood Hits	111
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

MY18A_HUMAN
NC score	0.046877 (rank : 121)	θ value	2.36792 (rank : 103)
Query Neighborhood Hits	178	Target Neighborhood Hits	1929	Shared Neighborhood Hits	114
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

GOGA5_MOUSE
NC score	0.046474 (rank : 122)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	178	Target Neighborhood Hits	1434	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QYE6, O88317, Q3TGE7, Q3U6S5, Q3UUF9	Gene names	Golga5, Retii
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (Sumiko protein) (Ret-II protein).

CENPF_HUMAN
NC score	0.046293 (rank : 123)	θ value	0.279714 (rank : 58)
Query Neighborhood Hits	178	Target Neighborhood Hits	1932	Shared Neighborhood Hits	102
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

PPIG_HUMAN
NC score	0.045938 (rank : 124)	θ value	0.62314 (rank : 71)
Query Neighborhood Hits	178	Target Neighborhood Hits	670	Shared Neighborhood Hits	69
SwissProt Accessions	Q13427, O00706, Q96DG9	Gene names	PPIG
Domain Architecture
Description	Peptidyl-prolyl cis-trans isomerase G (EC 5.2.1.8) (Peptidyl-prolyl isomerase G) (PPIase G) (Rotamase G) (Cyclophilin G) (Clk-associating RS-cyclophilin) (CARS-cyclophilin) (CARS-Cyp) (SR-cyclophilin) (SRcyp) (SR-cyp) (CASP10).

HMMR_HUMAN
NC score	0.045584 (rank : 125)	θ value	1.81305 (rank : 92)
Query Neighborhood Hits	178	Target Neighborhood Hits	1082	Shared Neighborhood Hits	85
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

EEA1_HUMAN
NC score	0.045211 (rank : 126)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	178	Target Neighborhood Hits	1796	Shared Neighborhood Hits	107
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

ARI5B_HUMAN
NC score	0.045135 (rank : 127)	θ value	4.03905 (rank : 111)
Query Neighborhood Hits	178	Target Neighborhood Hits	328	Shared Neighborhood Hits	17
SwissProt Accessions	Q14865, Q7Z3M4, Q8N421, Q9H786	Gene names	ARID5B, DESRT, MRF2
Domain Architecture
Description	AT-rich interactive domain-containing protein 5B (ARID domain- containing protein 5B) (Mrf1-like) (Modulator recognition factor 2) (MRF-2).

MACF4_HUMAN
NC score	0.044995 (rank : 128)	θ value	0.47712 (rank : 65)
Query Neighborhood Hits	178	Target Neighborhood Hits	1321	Shared Neighborhood Hits	86
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

CF182_HUMAN
NC score	0.043845 (rank : 129)	θ value	1.81305 (rank : 89)
Query Neighborhood Hits	178	Target Neighborhood Hits	474	Shared Neighborhood Hits	65
SwissProt Accessions	Q8IYX8	Gene names	C6orf182
Domain Architecture	No domain graphic available
Description	Protein C6orf182.

DMD_MOUSE
NC score	0.043590 (rank : 130)	θ value	0.365318 (rank : 62)
Query Neighborhood Hits	178	Target Neighborhood Hits	1111	Shared Neighborhood Hits	82
SwissProt Accessions	P11531, O35653, Q60703	Gene names	Dmd
Domain Architecture
Description	Dystrophin.

GOGA5_HUMAN
NC score	0.043188 (rank : 131)	θ value	1.38821 (rank : 81)
Query Neighborhood Hits	178	Target Neighborhood Hits	1168	Shared Neighborhood Hits	94
SwissProt Accessions	Q8TBA6, O95287, Q03962, Q9UQQ7	Gene names	GOLGA5, RETII, RFG5
Domain Architecture
Description	Golgin subfamily A member 5 (Golgin-84) (RET-fused gene 5 protein) (Ret-II protein).

KI21A_HUMAN
NC score	0.043007 (rank : 132)	θ value	0.0330416 (rank : 46)
Query Neighborhood Hits	178	Target Neighborhood Hits	1543	Shared Neighborhood Hits	95
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

FLIP1_HUMAN
NC score	0.042613 (rank : 133)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	178	Target Neighborhood Hits	1405	Shared Neighborhood Hits	101
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

CING_MOUSE
NC score	0.042541 (rank : 134)	θ value	4.03905 (rank : 112)
Query Neighborhood Hits	178	Target Neighborhood Hits	1432	Shared Neighborhood Hits	103
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

GRAP1_MOUSE
NC score	0.042298 (rank : 135)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	178	Target Neighborhood Hits	1234	Shared Neighborhood Hits	97
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

SPTB2_HUMAN
NC score	0.042192 (rank : 136)	θ value	1.38821 (rank : 87)
Query Neighborhood Hits	178	Target Neighborhood Hits	748	Shared Neighborhood Hits	82
SwissProt Accessions	Q01082, O60837, Q16057	Gene names	SPTBN1, SPTB2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

MACF1_HUMAN
NC score	0.042099 (rank : 137)	θ value	0.47712 (rank : 64)
Query Neighborhood Hits	178	Target Neighborhood Hits	1341	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

TRAK1_HUMAN
NC score	0.041814 (rank : 138)	θ value	1.06291 (rank : 80)
Query Neighborhood Hits	178	Target Neighborhood Hits	660	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UPV9, Q96B69	Gene names	TRAK1, KIAA1042, OIP106
Domain Architecture	No domain graphic available
Description	Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase- interacting protein).

MY18A_MOUSE
NC score	0.041625 (rank : 139)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	178	Target Neighborhood Hits	1989	Shared Neighborhood Hits	110
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TR150_HUMAN
NC score	0.041608 (rank : 140)	θ value	4.03905 (rank : 121)
Query Neighborhood Hits	178	Target Neighborhood Hits	313	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Y2W1, Q5VTK6	Gene names	THRAP3, TRAP150
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 3 (Thyroid hormone receptor-associated protein complex 150 kDa component) (Trap150).

CI093_HUMAN
NC score	0.041193 (rank : 141)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	178	Target Neighborhood Hits	1088	Shared Neighborhood Hits	89
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

LIMA1_HUMAN
NC score	0.040437 (rank : 142)	θ value	0.279714 (rank : 59)
Query Neighborhood Hits	178	Target Neighborhood Hits	309	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

MYH11_HUMAN
NC score	0.040355 (rank : 143)	θ value	4.03905 (rank : 118)
Query Neighborhood Hits	178	Target Neighborhood Hits	1806	Shared Neighborhood Hits	111
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

CR034_MOUSE
NC score	0.040279 (rank : 144)	θ value	2.36792 (rank : 96)
Query Neighborhood Hits	178	Target Neighborhood Hits	643	Shared Neighborhood Hits	76
SwissProt Accessions	Q8CDV0	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C18orf34 homolog.

CCDC6_HUMAN
NC score	0.040250 (rank : 145)	θ value	3.0926 (rank : 105)
Query Neighborhood Hits	178	Target Neighborhood Hits	723	Shared Neighborhood Hits	77
SwissProt Accessions	Q16204, Q15250	Gene names	CCDC6, D10S170
Domain Architecture
Description	Coiled-coil domain-containing protein 6 (H4 protein) (Papillary thyroid carcinoma-encoded protein).

SPTB2_MOUSE
NC score	0.039518 (rank : 146)	θ value	1.38821 (rank : 88)
Query Neighborhood Hits	178	Target Neighborhood Hits	770	Shared Neighborhood Hits	78
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

NIN_MOUSE
NC score	0.039471 (rank : 147)	θ value	5.27518 (rank : 134)
Query Neighborhood Hits	178	Target Neighborhood Hits	1376	Shared Neighborhood Hits	98
SwissProt Accessions	Q61043, Q6ZPM7	Gene names	Nin, Kiaa1565
Domain Architecture	No domain graphic available
Description	Ninein.

SDCG8_HUMAN
NC score	0.039263 (rank : 148)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	178	Target Neighborhood Hits	1002	Shared Neighborhood Hits	85
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

MACF1_MOUSE
NC score	0.039245 (rank : 149)	θ value	5.27518 (rank : 129)
Query Neighborhood Hits	178	Target Neighborhood Hits	1313	Shared Neighborhood Hits	84
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

UBP8_HUMAN
NC score	0.038517 (rank : 150)	θ value	0.0330416 (rank : 48)
Query Neighborhood Hits	178	Target Neighborhood Hits	751	Shared Neighborhood Hits	77
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

CTGE5_MOUSE
NC score	0.038372 (rank : 151)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	178	Target Neighborhood Hits	928	Shared Neighborhood Hits	92
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

KINH_HUMAN
NC score	0.037626 (rank : 152)	θ value	5.27518 (rank : 128)
Query Neighborhood Hits	178	Target Neighborhood Hits	1231	Shared Neighborhood Hits	96
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

STMN2_HUMAN
NC score	0.037303 (rank : 153)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	178	Target Neighborhood Hits	458	Shared Neighborhood Hits	58
SwissProt Accessions	Q93045, O14952, Q6PK68	Gene names	STMN2, SCG10, SCGN10
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

STMN2_MOUSE
NC score	0.037303 (rank : 154)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	178	Target Neighborhood Hits	458	Shared Neighborhood Hits	58
SwissProt Accessions	P55821	Gene names	Stmn2, Scg10, Scgn10, Stmb2
Domain Architecture
Description	Stathmin-2 (SCG10 protein) (Superior cervical ganglion-10 protein).

MYH13_HUMAN
NC score	0.036795 (rank : 155)	θ value	4.03905 (rank : 119)
Query Neighborhood Hits	178	Target Neighborhood Hits	1504	Shared Neighborhood Hits	99
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH8_MOUSE
NC score	0.036544 (rank : 156)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	178	Target Neighborhood Hits	1600	Shared Neighborhood Hits	105
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

STIM1_MOUSE
NC score	0.036225 (rank : 157)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	178	Target Neighborhood Hits	660	Shared Neighborhood Hits	73
SwissProt Accessions	P70302	Gene names	Stim1, Sim
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

TXLNB_HUMAN
NC score	0.035888 (rank : 158)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	178	Target Neighborhood Hits	912	Shared Neighborhood Hits	75
SwissProt Accessions	Q8N3L3, Q76L25, Q86T52, Q8N3S2	Gene names	TXLNB, C6orf198, MDP77
Domain Architecture	No domain graphic available
Description	Beta-taxilin (Muscle-derived protein 77) (hMDP77).

K0831_MOUSE
NC score	0.034699 (rank : 159)	θ value	3.0926 (rank : 108)
Query Neighborhood Hits	178	Target Neighborhood Hits	277	Shared Neighborhood Hits	45
SwissProt Accessions	Q8CDJ3, Q69ZY1, Q6PFY6, Q8C6N0, Q8R3M3	Gene names	Kiaa0831, D14Ertd436e
Domain Architecture	No domain graphic available
Description	Protein KIAA0831.

STIM1_HUMAN
NC score	0.034687 (rank : 160)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	178	Target Neighborhood Hits	665	Shared Neighborhood Hits	72
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

NUP88_HUMAN
NC score	0.033916 (rank : 161)	θ value	5.27518 (rank : 135)
Query Neighborhood Hits	178	Target Neighborhood Hits	354	Shared Neighborhood Hits	56
SwissProt Accessions	Q99567, Q9BWE5	Gene names	NUP88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

KI21A_MOUSE
NC score	0.033645 (rank : 162)	θ value	0.62314 (rank : 70)
Query Neighborhood Hits	178	Target Neighborhood Hits	1317	Shared Neighborhood Hits	87
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

UBP10_HUMAN
NC score	0.033176 (rank : 163)	θ value	0.125558 (rank : 52)
Query Neighborhood Hits	178	Target Neighborhood Hits	153	Shared Neighborhood Hits	6
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

CTGE5_HUMAN
NC score	0.032881 (rank : 164)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	178	Target Neighborhood Hits	800	Shared Neighborhood Hits	83
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

MYH4_MOUSE
NC score	0.032828 (rank : 165)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	178	Target Neighborhood Hits	1476	Shared Neighborhood Hits	95
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

ITSN1_HUMAN
NC score	0.032425 (rank : 166)	θ value	3.0926 (rank : 107)
Query Neighborhood Hits	178	Target Neighborhood Hits	1757	Shared Neighborhood Hits	100
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

AMOT_HUMAN
NC score	0.032189 (rank : 167)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	178	Target Neighborhood Hits	712	Shared Neighborhood Hits	76
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

SPTB1_HUMAN
NC score	0.032175 (rank : 168)	θ value	1.06291 (rank : 78)
Query Neighborhood Hits	178	Target Neighborhood Hits	541	Shared Neighborhood Hits	61
SwissProt Accessions	P11277, Q15510, Q15519	Gene names	SPTB, SPTB1
Domain Architecture
Description	Spectrin beta chain, erythrocyte (Beta-I spectrin).

ITSN2_MOUSE
NC score	0.032097 (rank : 169)	θ value	1.81305 (rank : 93)
Query Neighborhood Hits	178	Target Neighborhood Hits	1371	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

MINT_HUMAN
NC score	0.031470 (rank : 170)	θ value	5.27518 (rank : 131)
Query Neighborhood Hits	178	Target Neighborhood Hits	1291	Shared Neighborhood Hits	64
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MPP10_HUMAN
NC score	0.031077 (rank : 171)	θ value	2.36792 (rank : 102)
Query Neighborhood Hits	178	Target Neighborhood Hits	306	Shared Neighborhood Hits	37
SwissProt Accessions	O00566	Gene names	MPHOSPH10, MPP10
Domain Architecture
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

ITSN2_HUMAN
NC score	0.031036 (rank : 172)	θ value	2.36792 (rank : 99)
Query Neighborhood Hits	178	Target Neighborhood Hits	1173	Shared Neighborhood Hits	89
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

DNJC8_MOUSE
NC score	0.030465 (rank : 173)	θ value	2.36792 (rank : 97)
Query Neighborhood Hits	178	Target Neighborhood Hits	392	Shared Neighborhood Hits	36
SwissProt Accessions	Q6NZB0, Q6PG72, Q8C2M6	Gene names	Dnajc8
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 8.

AMOL1_MOUSE
NC score	0.030304 (rank : 174)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	178	Target Neighborhood Hits	445	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D4H4, Q571F1	Gene names	Amotl1
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 1.

MRCKB_HUMAN
NC score	0.029487 (rank : 175)	θ value	0.0193708 (rank : 42)
Query Neighborhood Hits	178	Target Neighborhood Hits	2239	Shared Neighborhood Hits	102
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

GRIN1_HUMAN
NC score	0.029072 (rank : 176)	θ value	4.03905 (rank : 116)
Query Neighborhood Hits	178	Target Neighborhood Hits	681	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

SPTN2_HUMAN
NC score	0.028516 (rank : 177)	θ value	1.06291 (rank : 79)
Query Neighborhood Hits	178	Target Neighborhood Hits	535	Shared Neighborhood Hits	49
SwissProt Accessions	O15020, O14872, O14873	Gene names	SPTBN2, KIAA0302
Domain Architecture
Description	Spectrin beta chain, brain 2 (Spectrin, non-erythroid beta chain 2) (Beta-III spectrin).

SH24A_HUMAN
NC score	0.028397 (rank : 178)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	178	Target Neighborhood Hits	455	Shared Neighborhood Hits	47
SwissProt Accessions	Q9H788, Q5XKC1, Q6NXE9, Q86YM2, Q96C88, Q9H7F7	Gene names	SH2D4A, SH2A
Domain Architecture	No domain graphic available
Description	SH2 domain-containing protein 4A (Protein SH(2)A).

CLSPN_HUMAN
NC score	0.028353 (rank : 179)	θ value	4.03905 (rank : 113)
Query Neighborhood Hits	178	Target Neighborhood Hits	433	Shared Neighborhood Hits	64
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

NUP88_MOUSE
NC score	0.028195 (rank : 180)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	178	Target Neighborhood Hits	239	Shared Neighborhood Hits	33
SwissProt Accessions	Q8CEC0, Q80Z13, Q8K090	Gene names	Nup88
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup88 (Nucleoporin Nup88) (88 kDa nuclear pore complex protein).

KIF23_HUMAN
NC score	0.026868 (rank : 181)	θ value	5.27518 (rank : 127)
Query Neighborhood Hits	178	Target Neighborhood Hits	618	Shared Neighborhood Hits	69
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

RUFY3_HUMAN
NC score	0.026851 (rank : 182)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	178	Target Neighborhood Hits	594	Shared Neighborhood Hits	69
SwissProt Accessions	Q7L099, O94948, Q9UI00	Gene names	RUFY3, KIAA0871
Domain Architecture	No domain graphic available
Description	Protein RUFY3 (Rap2-interacting protein x) (RIPx).

DNJC8_HUMAN
NC score	0.026788 (rank : 183)	θ value	4.03905 (rank : 114)
Query Neighborhood Hits	178	Target Neighborhood Hits	380	Shared Neighborhood Hits	32
SwissProt Accessions	O75937, Q6IBA4, Q8N4Z5, Q9P051, Q9P067	Gene names	DNAJC8, SPF31
Domain Architecture
Description	DnaJ homolog subfamily C member 8 (Splicing protein spf31).

STK10_MOUSE
NC score	0.026226 (rank : 184)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	178	Target Neighborhood Hits	2132	Shared Neighborhood Hits	109
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

MYO5B_HUMAN
NC score	0.026143 (rank : 185)	θ value	5.27518 (rank : 133)
Query Neighborhood Hits	178	Target Neighborhood Hits	911	Shared Neighborhood Hits	85
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

E41L2_MOUSE
NC score	0.025229 (rank : 186)	θ value	2.36792 (rank : 98)
Query Neighborhood Hits	178	Target Neighborhood Hits	459	Shared Neighborhood Hits	44
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MRCKB_MOUSE
NC score	0.025095 (rank : 187)	θ value	1.06291 (rank : 75)
Query Neighborhood Hits	178	Target Neighborhood Hits	2180	Shared Neighborhood Hits	101
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

CTRO_MOUSE
NC score	0.024224 (rank : 188)	θ value	1.81305 (rank : 90)
Query Neighborhood Hits	178	Target Neighborhood Hits	2344	Shared Neighborhood Hits	105
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DDX25_MOUSE
NC score	0.024079 (rank : 189)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	178	Target Neighborhood Hits	98	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QY15, Q8R1B6	Gene names	Ddx25, Grth
Domain Architecture
Description	ATP-dependent RNA helicase DDX25 (EC 3.6.1.-) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase).

TAOK1_HUMAN
NC score	0.023140 (rank : 190)	θ value	0.0113563 (rank : 40)
Query Neighborhood Hits	178	Target Neighborhood Hits	1734	Shared Neighborhood Hits	98
SwissProt Accessions	Q7L7X3, Q96L75, Q9H2K7, Q9H7S5, Q9P2I6	Gene names	TAOK1, KIAA1361, MAP3K16
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1) (STE20-like kinase PSK2) (Kinase from chicken homolog B) (hKFC-B).

NU153_HUMAN
NC score	0.022684 (rank : 191)	θ value	1.81305 (rank : 94)
Query Neighborhood Hits	178	Target Neighborhood Hits	227	Shared Neighborhood Hits	7
SwissProt Accessions	P49790	Gene names	NUP153
Domain Architecture
Description	Nuclear pore complex protein Nup153 (Nucleoporin Nup153) (153 kDa nucleoporin).

TAOK1_MOUSE
NC score	0.022079 (rank : 192)	θ value	0.0252991 (rank : 45)
Query Neighborhood Hits	178	Target Neighborhood Hits	1720	Shared Neighborhood Hits	95
SwissProt Accessions	Q5F2E8, Q69ZL2, Q8JZX2, Q91VG7	Gene names	Taok1, Kiaa1361
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase TAO1 (EC 2.7.11.1) (Thousand and one amino acid protein 1).

UB2L3_HUMAN
NC score	0.021634 (rank : 193)	θ value	0.47712 (rank : 66)
Query Neighborhood Hits	178	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	P68036, P51966, P70653, Q9HAV1	Gene names	UBE2L3, UBCE7, UBCH7
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 L3 (EC 6.3.2.19) (Ubiquitin-protein ligase L3) (Ubiquitin carrier protein L3) (UbcH7) (E2-F1) (L-UBC).

UB2L3_MOUSE
NC score	0.021634 (rank : 194)	θ value	0.47712 (rank : 67)
Query Neighborhood Hits	178	Target Neighborhood Hits	63	Shared Neighborhood Hits	4
SwissProt Accessions	P68037, P51966, P70653, Q9HAV1	Gene names	Ube2l3, Ubce7
Domain Architecture	No domain graphic available
Description	Ubiquitin-conjugating enzyme E2 L3 (EC 6.3.2.19) (Ubiquitin-protein ligase L3) (Ubiquitin carrier protein L3) (UbcM4).

K0157_MOUSE
NC score	0.021602 (rank : 195)	θ value	4.03905 (rank : 117)
Query Neighborhood Hits	178	Target Neighborhood Hits	116	Shared Neighborhood Hits	9
SwissProt Accessions	Q3TCJ1, Q3TB08, Q8K0R4	Gene names	Kiaa0157
Domain Architecture	No domain graphic available
Description	Protein KIAA0157.

CTRO_HUMAN
NC score	0.020521 (rank : 196)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	178	Target Neighborhood Hits	2092	Shared Neighborhood Hits	99
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

RRMJ3_MOUSE
NC score	0.019853 (rank : 197)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	178	Target Neighborhood Hits	163	Shared Neighborhood Hits	29
SwissProt Accessions	Q9DBE9, Q3ULI1, Q921I7	Gene names	Ftsj3
Domain Architecture	No domain graphic available
Description	Putative rRNA methyltransferase 3 (EC 2.1.1.-) (rRNA (uridine-2'-O-)- methyltransferase 3).

KCNN2_MOUSE
NC score	0.019746 (rank : 198)	θ value	1.38821 (rank : 84)
Query Neighborhood Hits	178	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	P58390	Gene names	Kcnn2, Sk2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KCNN2_HUMAN
NC score	0.019601 (rank : 199)	θ value	1.38821 (rank : 83)
Query Neighborhood Hits	178	Target Neighborhood Hits	117	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H2S1	Gene names	KCNN2
Domain Architecture
Description	Small conductance calcium-activated potassium channel protein 2 (SK2).

KDEL2_HUMAN
NC score	0.019337 (rank : 200)	θ value	2.36792 (rank : 100)
Query Neighborhood Hits	178	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z4H8, Q6UWW2, Q6ZUM9, Q8N7L8, Q8NE24	Gene names	KDELC2
Domain Architecture	No domain graphic available
Description	KDEL motif-containing protein 2 precursor.

EXOC2_HUMAN
NC score	0.019180 (rank : 201)	θ value	1.81305 (rank : 91)
Query Neighborhood Hits	178	Target Neighborhood Hits	34	Shared Neighborhood Hits	3
SwissProt Accessions	Q96KP1, Q5JPC8, Q96AN6, Q9NUZ8, Q9UJM7	Gene names	EXOC2, SEC5, SEC5L1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

MRCKA_HUMAN
NC score	0.018609 (rank : 202)	θ value	3.0926 (rank : 109)
Query Neighborhood Hits	178	Target Neighborhood Hits	1999	Shared Neighborhood Hits	95
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

DDX51_HUMAN
NC score	0.017759 (rank : 203)	θ value	0.62314 (rank : 68)
Query Neighborhood Hits	178	Target Neighborhood Hits	332	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N8A6, Q5CZ71, Q8IXK5, Q96ED1	Gene names	DDX51
Domain Architecture	No domain graphic available
Description	ATP-dependent RNA helicase DDX51 (EC 3.6.1.-) (DEAD box protein 51).

HORN_MOUSE
NC score	0.017607 (rank : 204)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	178	Target Neighborhood Hits	218	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VHD8	Gene names	Hrnr
Domain Architecture
Description	Hornerin.

LAMC2_HUMAN
NC score	0.017528 (rank : 205)	θ value	0.163984 (rank : 54)
Query Neighborhood Hits	178	Target Neighborhood Hits	715	Shared Neighborhood Hits	50
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

DMN_HUMAN
NC score	0.016969 (rank : 206)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	178	Target Neighborhood Hits	690	Shared Neighborhood Hits	63
SwissProt Accessions	O15061	Gene names	DMN, KIAA0353
Domain Architecture
Description	Desmuslin.

RGNEF_MOUSE
NC score	0.016516 (rank : 207)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	178	Target Neighborhood Hits	641	Shared Neighborhood Hits	55
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

EXOC2_MOUSE
NC score	0.016497 (rank : 208)	θ value	5.27518 (rank : 126)
Query Neighborhood Hits	178	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D4H1	Gene names	Exoc2, Sec5, Sec5l1
Domain Architecture
Description	Exocyst complex component 2 (Exocyst complex component Sec5).

SFPQ_MOUSE
NC score	0.015984 (rank : 209)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	178	Target Neighborhood Hits	958	Shared Neighborhood Hits	66
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

PESC_HUMAN
NC score	0.015329 (rank : 210)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	178	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	O00541, Q6IC29	Gene names	PES1
Domain Architecture
Description	Pescadillo homolog 1.

SETX_HUMAN
NC score	0.015311 (rank : 211)	θ value	5.27518 (rank : 138)
Query Neighborhood Hits	178	Target Neighborhood Hits	368	Shared Neighborhood Hits	26
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

SFPQ_HUMAN
NC score	0.015177 (rank : 212)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	178	Target Neighborhood Hits	986	Shared Neighborhood Hits	64
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

PARD3_HUMAN
NC score	0.015036 (rank : 213)	θ value	3.0926 (rank : 110)
Query Neighborhood Hits	178	Target Neighborhood Hits	312	Shared Neighborhood Hits	18
SwissProt Accessions	Q8TEW0, Q8TEW1, Q8TEW2, Q8TEW3, Q96K28, Q96RM6, Q96RM7, Q9BY57, Q9BY58, Q9HC48, Q9NWL4, Q9NYE6	Gene names	PARD3, PAR3, PAR3A
Domain Architecture
Description	Partitioning-defective 3 homolog (PARD-3) (PAR-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2- 5) (PAR3-alpha).

CALI_HUMAN
NC score	0.014558 (rank : 214)	θ value	1.06291 (rank : 74)
Query Neighborhood Hits	178	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	Q13939, Q9BXG7	Gene names	CCIN
Domain Architecture
Description	Calicin.

DUT_HUMAN
NC score	0.012718 (rank : 215)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	178	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	P33316, O14785, Q16708, Q16860, Q96Q81	Gene names	DUT
Domain Architecture
Description	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial precursor (EC 3.6.1.23) (dUTPase) (dUTP pyrophosphatase).

TRIM8_HUMAN
NC score	0.011850 (rank : 216)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	178	Target Neighborhood Hits	650	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BZR9, Q9C028	Gene names	TRIM8, GERP, RNF27
Domain Architecture
Description	Tripartite motif-containing protein 8 (RING finger protein 27) (Glioblastoma-expressed RING finger protein).

MRT4_HUMAN
NC score	0.011333 (rank : 217)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	178	Target Neighborhood Hits	6	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKD2, Q96SS6, Q9BPV9	Gene names	MRT4, C1orf33
Domain Architecture	No domain graphic available
Description	mRNA turnover protein 4 homolog.

GBF1_HUMAN
NC score	0.010898 (rank : 218)	θ value	4.03905 (rank : 115)
Query Neighborhood Hits	178	Target Neighborhood Hits	142	Shared Neighborhood Hits	8
SwissProt Accessions	Q92538, Q5VXX3, Q96CK6, Q96HZ3, Q9H473	Gene names	GBF1, KIAA0248
Domain Architecture
Description	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (BFA-resistant GEF 1).

K2C1B_HUMAN
NC score	0.010250 (rank : 219)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	178	Target Neighborhood Hits	542	Shared Neighborhood Hits	58
SwissProt Accessions	Q7Z794, Q7RTS8	Gene names	KRT1B
Domain Architecture	No domain graphic available
Description	Keratin, type II cytoskeletal 1b.

PACN3_MOUSE
NC score	0.009429 (rank : 220)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	178	Target Neighborhood Hits	380	Shared Neighborhood Hits	28
SwissProt Accessions	Q99JB8, Q9EQP9	Gene names	Pacsin3
Domain Architecture
Description	Protein kinase C and casein kinase II substrate protein 3.

RGS2_MOUSE
NC score	0.007594 (rank : 221)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	178	Target Neighborhood Hits	52	Shared Neighborhood Hits	4
SwissProt Accessions	O08849, Q544S7, Q91WX1, Q9JL24	Gene names	Rgs2
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2).

PGAM2_MOUSE
NC score	0.006800 (rank : 222)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	178	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	O70250	Gene names	Pgam2
Domain Architecture
Description	Phosphoglycerate mutase 2 (EC 5.4.2.1) (EC 5.4.2.4) (EC 3.1.3.13) (Phosphoglycerate mutase isozyme M) (PGAM-M) (BPG-dependent PGAM 2) (Muscle-specific phosphoglycerate mutase).

RGS2_HUMAN
NC score	0.006715 (rank : 223)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	178	Target Neighborhood Hits	49	Shared Neighborhood Hits	4
SwissProt Accessions	P41220	Gene names	RGS2, G0S8
Domain Architecture
Description	Regulator of G-protein signaling 2 (RGS2) (G0/G1 switch regulatory protein 8).

PGAM2_HUMAN
NC score	0.006125 (rank : 224)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	178	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	P15259	Gene names	PGAM2, PGAMM
Domain Architecture
Description	Phosphoglycerate mutase 2 (EC 5.4.2.1) (EC 5.4.2.4) (EC 3.1.3.13) (Phosphoglycerate mutase isozyme M) (PGAM-M) (BPG-dependent PGAM 2) (Muscle-specific phosphoglycerate mutase).

DDX53_HUMAN
NC score	0.006004 (rank : 225)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	178	Target Neighborhood Hits	124	Shared Neighborhood Hits	6
SwissProt Accessions	Q86TM3, Q6NVV4	Gene names	DDX53, CAGE
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX53 (EC 3.6.1.-) (DEAD box protein 53) (DEAD box protein CAGE) (Cancer-associated gene protein).

LRFN5_HUMAN
NC score	0.005851 (rank : 226)	θ value	1.38821 (rank : 85)
Query Neighborhood Hits	178	Target Neighborhood Hits	464	Shared Neighborhood Hits	6
SwissProt Accessions	Q96NI6, Q86XL2	Gene names	LRFN5, C14orf146
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

HPLN2_MOUSE
NC score	0.005260 (rank : 227)	θ value	3.0926 (rank : 106)
Query Neighborhood Hits	178	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ESM3	Gene names	Hapln2, Bral1
Domain Architecture
Description	Hyaluronan and proteoglycan link protein 2 precursor (Brain link protein 1).

LRFN5_MOUSE
NC score	0.004810 (rank : 228)	θ value	2.36792 (rank : 101)
Query Neighborhood Hits	178	Target Neighborhood Hits	472	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

COCA1_HUMAN
NC score	0.004092 (rank : 229)	θ value	2.36792 (rank : 95)
Query Neighborhood Hits	178	Target Neighborhood Hits	458	Shared Neighborhood Hits	9
SwissProt Accessions	Q99715, Q99716	Gene names	COL12A1
Domain Architecture
Description	Collagen alpha-1(XII) chain precursor.

MYO3A_HUMAN
NC score	0.003724 (rank : 230)	θ value	5.27518 (rank : 132)
Query Neighborhood Hits	178	Target Neighborhood Hits	1033	Shared Neighborhood Hits	37
SwissProt Accessions	Q8NEV4, Q8WX17, Q9NYS8	Gene names	MYO3A
Domain Architecture
Description	Myosin IIIA (EC 2.7.11.1).

SPEG_HUMAN
NC score	0.001152 (rank : 231)	θ value	2.36792 (rank : 104)
Query Neighborhood Hits	178	Target Neighborhood Hits	1762	Shared Neighborhood Hits	25
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

CP2A5_MOUSE
NC score	0.000766 (rank : 232)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	178	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	P20852	Gene names	Cyp2a5, Cyp2a-5
Domain Architecture
Description	Cytochrome P450 2A5 (EC 1.14.14.1) (CYPIIA5) (Coumarin 7-hydroxylase) (P450-15-COH) (P450-IIA3.2).

ZBT40_HUMAN
NC score	-0.000356 (rank : 233)	θ value	0.62314 (rank : 72)
Query Neighborhood Hits	178	Target Neighborhood Hits	949	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

ULK2_HUMAN
NC score	-0.000810 (rank : 234)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	178	Target Neighborhood Hits	979	Shared Neighborhood Hits	14
SwissProt Accessions	Q8IYT8, O75119	Gene names	ULK2, KIAA0623
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK2 (EC 2.7.11.1) (Unc-51-like kinase 2).

FBN3_HUMAN
NC score	-0.002090 (rank : 235)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	178	Target Neighborhood Hits	543	Shared Neighborhood Hits	4
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

ZN263_HUMAN
NC score	-0.005553 (rank : 236)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	178	Target Neighborhood Hits	795	Shared Neighborhood Hits	6
SwissProt Accessions	O14978, O43387, Q96H95	Gene names	ZNF263, FPM315
Domain Architecture
Description	Zinc finger protein 263 (Zinc finger protein FPM315).