Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : CBX7_HUMAN

For an explanation of this page, click here

CBX7_HUMAN
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CBX7_HUMAN
θ value	3.64273e-126 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	48	Target Neighborhood Hits	48	Shared Neighborhood Hits	48
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

CBX7_MOUSE
θ value	1.46607e-42 (rank : 2)	NC score	0.980389 (rank : 2)
Query Neighborhood Hits	48	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

CBX4_HUMAN
θ value	5.77852e-31 (rank : 3)	NC score	0.895595 (rank : 6)
Query Neighborhood Hits	48	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	O00257, Q96C04	Gene names	CBX4
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (hPc2).

CBX4_MOUSE
θ value	2.19584e-30 (rank : 4)	NC score	0.893574 (rank : 7)
Query Neighborhood Hits	48	Target Neighborhood Hits	64	Shared Neighborhood Hits	32
SwissProt Accessions	O55187	Gene names	Cbx4, Pc2
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (mPc2).

CBX6_HUMAN
θ value	2.96777e-27 (rank : 5)	NC score	0.889845 (rank : 8)
Query Neighborhood Hits	48	Target Neighborhood Hits	104	Shared Neighborhood Hits	35
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX6_MOUSE
θ value	2.96777e-27 (rank : 6)	NC score	0.901308 (rank : 3)
Query Neighborhood Hits	48	Target Neighborhood Hits	50	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DBY5, Q8BZH5	Gene names	Cbx6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX8_HUMAN
θ value	1.92365e-26 (rank : 7)	NC score	0.896305 (rank : 5)
Query Neighborhood Hits	48	Target Neighborhood Hits	67	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HC52, Q96H39, Q9NR07	Gene names	CBX8, PC3, RC1
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1).

CBX8_MOUSE
θ value	1.92365e-26 (rank : 8)	NC score	0.899941 (rank : 4)
Query Neighborhood Hits	48	Target Neighborhood Hits	46	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QXV1	Gene names	Cbx8, Pc3
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (mPc3).

CBX2_HUMAN
θ value	1.42661e-21 (rank : 9)	NC score	0.798947 (rank : 10)
Query Neighborhood Hits	48	Target Neighborhood Hits	264	Shared Neighborhood Hits	34
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

CBX2_MOUSE
θ value	1.42661e-21 (rank : 10)	NC score	0.849722 (rank : 9)
Query Neighborhood Hits	48	Target Neighborhood Hits	119	Shared Neighborhood Hits	34
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

CBX1_HUMAN
θ value	1.06045e-08 (rank : 11)	NC score	0.695395 (rank : 11)
Query Neighborhood Hits	48	Target Neighborhood Hits	44	Shared Neighborhood Hits	34
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	1.06045e-08 (rank : 12)	NC score	0.695395 (rank : 12)
Query Neighborhood Hits	48	Target Neighborhood Hits	44	Shared Neighborhood Hits	34
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX5_HUMAN
θ value	2.36244e-08 (rank : 13)	NC score	0.688554 (rank : 13)
Query Neighborhood Hits	48	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX3_HUMAN
θ value	5.26297e-08 (rank : 14)	NC score	0.674442 (rank : 15)
Query Neighborhood Hits	48	Target Neighborhood Hits	36	Shared Neighborhood Hits	33
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX5_MOUSE
θ value	5.26297e-08 (rank : 15)	NC score	0.688021 (rank : 14)
Query Neighborhood Hits	48	Target Neighborhood Hits	67	Shared Neighborhood Hits	34
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CBX3_MOUSE
θ value	2.61198e-07 (rank : 16)	NC score	0.662862 (rank : 16)
Query Neighborhood Hits	48	Target Neighborhood Hits	39	Shared Neighborhood Hits	33
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

MPP8_HUMAN
θ value	1.29631e-06 (rank : 17)	NC score	0.243413 (rank : 26)
Query Neighborhood Hits	48	Target Neighborhood Hits	948	Shared Neighborhood Hits	35
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

CDYL_MOUSE
θ value	6.43352e-06 (rank : 18)	NC score	0.439240 (rank : 17)
Query Neighborhood Hits	48	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WTK2	Gene names	Cdyl
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CDYL1_HUMAN
θ value	8.40245e-06 (rank : 19)	NC score	0.436922 (rank : 18)
Query Neighborhood Hits	48	Target Neighborhood Hits	92	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y232	Gene names	CDYL, CDYL1
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

SUV92_MOUSE
θ value	2.44474e-05 (rank : 20)	NC score	0.360703 (rank : 22)
Query Neighborhood Hits	48	Target Neighborhood Hits	59	Shared Neighborhood Hits	30
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

CDY1_HUMAN
θ value	4.1701e-05 (rank : 21)	NC score	0.415496 (rank : 21)
Query Neighborhood Hits	48	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y6F8, O14600	Gene names	CDY1
Domain Architecture
Description	Testis-specific chromodomain protein Y 1.

CDY2_HUMAN
θ value	4.1701e-05 (rank : 22)	NC score	0.416319 (rank : 20)
Query Neighborhood Hits	48	Target Neighborhood Hits	49	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y6F7	Gene names	CDY2A, CDY2
Domain Architecture
Description	Testis-specific chromodomain protein Y 2.

CDYL2_HUMAN
θ value	9.29e-05 (rank : 23)	NC score	0.431265 (rank : 19)
Query Neighborhood Hits	48	Target Neighborhood Hits	53	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N8U2	Gene names	CDYL2
Domain Architecture
Description	Chromodomain Y-like protein 2 (CDY-like 2).

SUV92_HUMAN
θ value	0.00035302 (rank : 24)	NC score	0.338432 (rank : 23)
Query Neighborhood Hits	48	Target Neighborhood Hits	54	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

CHD1_HUMAN
θ value	0.00102713 (rank : 25)	NC score	0.191595 (rank : 27)
Query Neighborhood Hits	48	Target Neighborhood Hits	337	Shared Neighborhood Hits	35
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

SUV91_MOUSE
θ value	0.00102713 (rank : 26)	NC score	0.337890 (rank : 24)
Query Neighborhood Hits	48	Target Neighborhood Hits	69	Shared Neighborhood Hits	30
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

CHD2_HUMAN
θ value	0.00298849 (rank : 27)	NC score	0.182163 (rank : 29)
Query Neighborhood Hits	48	Target Neighborhood Hits	360	Shared Neighborhood Hits	35
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

SUV91_HUMAN
θ value	0.00298849 (rank : 28)	NC score	0.315026 (rank : 25)
Query Neighborhood Hits	48	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

CHD1_MOUSE
θ value	0.00390308 (rank : 29)	NC score	0.190064 (rank : 28)
Query Neighborhood Hits	48	Target Neighborhood Hits	266	Shared Neighborhood Hits	36
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

ARI4A_HUMAN
θ value	0.0431538 (rank : 30)	NC score	0.087639 (rank : 37)
Query Neighborhood Hits	48	Target Neighborhood Hits	434	Shared Neighborhood Hits	14
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

MS3L1_MOUSE
θ value	0.125558 (rank : 31)	NC score	0.140002 (rank : 30)
Query Neighborhood Hits	48	Target Neighborhood Hits	67	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WVG9	Gene names	Msl3l1, Msl31
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

K1802_MOUSE
θ value	0.279714 (rank : 32)	NC score	0.017389 (rank : 70)
Query Neighborhood Hits	48	Target Neighborhood Hits	1596	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

CHD4_HUMAN
θ value	0.47712 (rank : 33)	NC score	0.095191 (rank : 34)
Query Neighborhood Hits	48	Target Neighborhood Hits	365	Shared Neighborhood Hits	26
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
θ value	0.47712 (rank : 34)	NC score	0.094917 (rank : 35)
Query Neighborhood Hits	48	Target Neighborhood Hits	408	Shared Neighborhood Hits	27
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD3_HUMAN
θ value	0.62314 (rank : 35)	NC score	0.106561 (rank : 33)
Query Neighborhood Hits	48	Target Neighborhood Hits	397	Shared Neighborhood Hits	32
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

MS3L1_HUMAN
θ value	1.06291 (rank : 36)	NC score	0.074096 (rank : 43)
Query Neighborhood Hits	48	Target Neighborhood Hits	60	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N5Y2, Q9UG70, Q9Y5Z8	Gene names	MSL3L1
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

CHD6_HUMAN
θ value	1.38821 (rank : 37)	NC score	0.080588 (rank : 42)
Query Neighborhood Hits	48	Target Neighborhood Hits	342	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CHD5_HUMAN
θ value	1.81305 (rank : 38)	NC score	0.090622 (rank : 36)
Query Neighborhood Hits	48	Target Neighborhood Hits	349	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

MYO15_MOUSE
θ value	3.0926 (rank : 39)	NC score	0.006940 (rank : 77)
Query Neighborhood Hits	48	Target Neighborhood Hits	467	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PLIN_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.017419 (rank : 69)
Query Neighborhood Hits	48	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	O60240, Q8N5Y6	Gene names	PLIN
Domain Architecture
Description	Perilipin (PERI) (Lipid droplet-associated protein).

ESPL1_HUMAN
θ value	5.27518 (rank : 41)	NC score	0.016203 (rank : 71)
Query Neighborhood Hits	48	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

NDF1_HUMAN
θ value	5.27518 (rank : 42)	NC score	0.016065 (rank : 72)
Query Neighborhood Hits	48	Target Neighborhood Hits	186	Shared Neighborhood Hits	5
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

PHLB1_HUMAN
θ value	5.27518 (rank : 43)	NC score	0.006316 (rank : 78)
Query Neighborhood Hits	48	Target Neighborhood Hits	1038	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

AHI1_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.002630 (rank : 79)
Query Neighborhood Hits	48	Target Neighborhood Hits	496	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).

DUS11_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.011766 (rank : 76)
Query Neighborhood Hits	48	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	O75319, Q6AI47, Q9BWE3	Gene names	DUSP11, PIR1
Domain Architecture
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

NDF1_MOUSE
θ value	8.99809 (rank : 46)	NC score	0.014570 (rank : 75)
Query Neighborhood Hits	48	Target Neighborhood Hits	209	Shared Neighborhood Hits	5
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

NDF2_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.015117 (rank : 73)
Query Neighborhood Hits	48	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF2_MOUSE
θ value	8.99809 (rank : 48)	NC score	0.014735 (rank : 74)
Query Neighborhood Hits	48	Target Neighborhood Hits	111	Shared Neighborhood Hits	5
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

AUHM_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.066883 (rank : 47)
Query Neighborhood Hits	48	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLZ3, Q80YD7, Q8QZS0, Q9CY78, Q9D155	Gene names	Auh
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding enoyl-CoA hydratase) (muAUH).

AUMH_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.066104 (rank : 48)
Query Neighborhood Hits	48	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q13825, Q8WUE4	Gene names	AUH
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding protein/enoyl-CoA hydratase).

BTAF1_HUMAN
θ value	θ > 10 (rank : 51)	NC score	0.055431 (rank : 58)
Query Neighborhood Hits	48	Target Neighborhood Hits	97	Shared Neighborhood Hits	8
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

CHD8_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.071292 (rank : 46)
Query Neighborhood Hits	48	Target Neighborhood Hits	235	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CHD9_HUMAN
θ value	θ > 10 (rank : 53)	NC score	0.072598 (rank : 44)
Query Neighborhood Hits	48	Target Neighborhood Hits	343	Shared Neighborhood Hits	18
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
θ value	θ > 10 (rank : 54)	NC score	0.072547 (rank : 45)
Query Neighborhood Hits	48	Target Neighborhood Hits	427	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

ECH1_HUMAN
θ value	θ > 10 (rank : 55)	NC score	0.084122 (rank : 39)
Query Neighborhood Hits	48	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q13011, Q8WVX0, Q96EZ9	Gene names	ECH1
Domain Architecture
Description	Delta3,5-delta2,4-dienoyl-CoA isomerase, mitochondrial precursor (EC 5.3.3.-).

ECH1_MOUSE
θ value	θ > 10 (rank : 56)	NC score	0.086644 (rank : 38)
Query Neighborhood Hits	48	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	O35459, Q5M8P6	Gene names	Ech1
Domain Architecture
Description	Delta3,5-delta2,4-dienoyl-CoA isomerase, mitochondrial precursor (EC 5.3.3.-).

ECHA_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.052984 (rank : 66)
Query Neighborhood Hits	48	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	P40939, Q16679, Q96GT7	Gene names	HADHA, HADH
Domain Architecture
Description	Trifunctional enzyme subunit alpha, mitochondrial precursor (TP-alpha) (78 kDa gastrin-binding protein) [Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)].

ECHM_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.081864 (rank : 41)
Query Neighborhood Hits	48	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P30084, O00739, Q5VWY1, Q96H54	Gene names	ECHS1
Domain Architecture
Description	Enoyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.17) (Short chain enoyl-CoA hydratase) (SCEH) (Enoyl-CoA hydratase 1).

ECHM_MOUSE
θ value	θ > 10 (rank : 59)	NC score	0.082344 (rank : 40)
Query Neighborhood Hits	48	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BH95, Q3TJK2, Q6GQS2, Q6PEN1, Q99LX7	Gene names	Echs1
Domain Architecture	No domain graphic available
Description	Enoyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.17) (Short chain enoyl-CoA hydratase) (SCEH) (Enoyl-CoA hydratase 1).

EP400_HUMAN
θ value	θ > 10 (rank : 60)	NC score	0.050226 (rank : 68)
Query Neighborhood Hits	48	Target Neighborhood Hits	556	Shared Neighborhood Hits	12
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

EP400_MOUSE
θ value	θ > 10 (rank : 61)	NC score	0.055014 (rank : 59)
Query Neighborhood Hits	48	Target Neighborhood Hits	592	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

ERCC6_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.057083 (rank : 56)
Query Neighborhood Hits	48	Target Neighborhood Hits	247	Shared Neighborhood Hits	8
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

INOC1_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.053822 (rank : 62)
Query Neighborhood Hits	48	Target Neighborhood Hits	181	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

INOC1_MOUSE
θ value	θ > 10 (rank : 64)	NC score	0.053822 (rank : 63)
Query Neighborhood Hits	48	Target Neighborhood Hits	178	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

PECI_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.125818 (rank : 31)
Query Neighborhood Hits	48	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	O75521, Q5JYK5, Q8N0X0, Q9BUE9, Q9H0T9, Q9NQH1, Q9NYH7, Q9UN55	Gene names	PECI, DRS1, HCA88
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (DBI-related protein 1) (DRS-1) (Hepatocellular carcinoma- associated antigen 88) (NY-REN-1 antigen).

PECI_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.125141 (rank : 32)
Query Neighborhood Hits	48	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WUR2	Gene names	Peci
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase).

RA54B_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.053742 (rank : 64)
Query Neighborhood Hits	48	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RA54B_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.053339 (rank : 65)
Query Neighborhood Hits	48	Target Neighborhood Hits	59	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RAD54_HUMAN
θ value	θ > 10 (rank : 69)	NC score	0.054338 (rank : 60)
Query Neighborhood Hits	48	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RAD54_MOUSE
θ value	θ > 10 (rank : 70)	NC score	0.053953 (rank : 61)
Query Neighborhood Hits	48	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

SETD2_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.051931 (rank : 67)
Query Neighborhood Hits	48	Target Neighborhood Hits	412	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

SMCA1_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.059874 (rank : 49)
Query Neighborhood Hits	48	Target Neighborhood Hits	105	Shared Neighborhood Hits	8
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA1_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.059668 (rank : 52)
Query Neighborhood Hits	48	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SMCA2_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.056699 (rank : 57)
Query Neighborhood Hits	48	Target Neighborhood Hits	503	Shared Neighborhood Hits	10
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SMCA4_HUMAN
θ value	θ > 10 (rank : 75)	NC score	0.058729 (rank : 53)
Query Neighborhood Hits	48	Target Neighborhood Hits	597	Shared Neighborhood Hits	12
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SMCA5_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.059682 (rank : 50)
Query Neighborhood Hits	48	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA5_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.059670 (rank : 51)
Query Neighborhood Hits	48	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMRCD_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.057113 (rank : 55)
Query Neighborhood Hits	48	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

SMRCD_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.057253 (rank : 54)
Query Neighborhood Hits	48	Target Neighborhood Hits	96	Shared Neighborhood Hits	8
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

Hits sorted by NC score

CBX7_HUMAN
NC score	0.999962 (rank : 1)	θ value	3.64273e-126 (rank : 1)
Query Neighborhood Hits	48	Target Neighborhood Hits	48	Shared Neighborhood Hits	48
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

CBX7_MOUSE
NC score	0.980389 (rank : 2)	θ value	1.46607e-42 (rank : 2)
Query Neighborhood Hits	48	Target Neighborhood Hits	38	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

CBX6_MOUSE
NC score	0.901308 (rank : 3)	θ value	2.96777e-27 (rank : 6)
Query Neighborhood Hits	48	Target Neighborhood Hits	50	Shared Neighborhood Hits	33
SwissProt Accessions	Q9DBY5, Q8BZH5	Gene names	Cbx6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX8_MOUSE
NC score	0.899941 (rank : 4)	θ value	1.92365e-26 (rank : 8)
Query Neighborhood Hits	48	Target Neighborhood Hits	46	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QXV1	Gene names	Cbx8, Pc3
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (mPc3).

CBX8_HUMAN
NC score	0.896305 (rank : 5)	θ value	1.92365e-26 (rank : 7)
Query Neighborhood Hits	48	Target Neighborhood Hits	67	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HC52, Q96H39, Q9NR07	Gene names	CBX8, PC3, RC1
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1).

CBX4_HUMAN
NC score	0.895595 (rank : 6)	θ value	5.77852e-31 (rank : 3)
Query Neighborhood Hits	48	Target Neighborhood Hits	68	Shared Neighborhood Hits	32
SwissProt Accessions	O00257, Q96C04	Gene names	CBX4
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (hPc2).

CBX4_MOUSE
NC score	0.893574 (rank : 7)	θ value	2.19584e-30 (rank : 4)
Query Neighborhood Hits	48	Target Neighborhood Hits	64	Shared Neighborhood Hits	32
SwissProt Accessions	O55187	Gene names	Cbx4, Pc2
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (mPc2).

CBX6_HUMAN
NC score	0.889845 (rank : 8)	θ value	2.96777e-27 (rank : 5)
Query Neighborhood Hits	48	Target Neighborhood Hits	104	Shared Neighborhood Hits	35
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX2_MOUSE
NC score	0.849722 (rank : 9)	θ value	1.42661e-21 (rank : 10)
Query Neighborhood Hits	48	Target Neighborhood Hits	119	Shared Neighborhood Hits	34
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

CBX2_HUMAN
NC score	0.798947 (rank : 10)	θ value	1.42661e-21 (rank : 9)
Query Neighborhood Hits	48	Target Neighborhood Hits	264	Shared Neighborhood Hits	34
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

CBX1_HUMAN
NC score	0.695395 (rank : 11)	θ value	1.06045e-08 (rank : 11)
Query Neighborhood Hits	48	Target Neighborhood Hits	44	Shared Neighborhood Hits	34
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.695395 (rank : 12)	θ value	1.06045e-08 (rank : 12)
Query Neighborhood Hits	48	Target Neighborhood Hits	44	Shared Neighborhood Hits	34
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX5_HUMAN
NC score	0.688554 (rank : 13)	θ value	2.36244e-08 (rank : 13)
Query Neighborhood Hits	48	Target Neighborhood Hits	70	Shared Neighborhood Hits	34
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
NC score	0.688021 (rank : 14)	θ value	5.26297e-08 (rank : 15)
Query Neighborhood Hits	48	Target Neighborhood Hits	67	Shared Neighborhood Hits	34
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CBX3_HUMAN
NC score	0.674442 (rank : 15)	θ value	5.26297e-08 (rank : 14)
Query Neighborhood Hits	48	Target Neighborhood Hits	36	Shared Neighborhood Hits	33
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX3_MOUSE
NC score	0.662862 (rank : 16)	θ value	2.61198e-07 (rank : 16)
Query Neighborhood Hits	48	Target Neighborhood Hits	39	Shared Neighborhood Hits	33
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CDYL_MOUSE
NC score	0.439240 (rank : 17)	θ value	6.43352e-06 (rank : 18)
Query Neighborhood Hits	48	Target Neighborhood Hits	69	Shared Neighborhood Hits	35
SwissProt Accessions	Q9WTK2	Gene names	Cdyl
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CDYL1_HUMAN
NC score	0.436922 (rank : 18)	θ value	8.40245e-06 (rank : 19)
Query Neighborhood Hits	48	Target Neighborhood Hits	92	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Y232	Gene names	CDYL, CDYL1
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CDYL2_HUMAN
NC score	0.431265 (rank : 19)	θ value	9.29e-05 (rank : 23)
Query Neighborhood Hits	48	Target Neighborhood Hits	53	Shared Neighborhood Hits	34
SwissProt Accessions	Q8N8U2	Gene names	CDYL2
Domain Architecture
Description	Chromodomain Y-like protein 2 (CDY-like 2).

CDY2_HUMAN
NC score	0.416319 (rank : 20)	θ value	4.1701e-05 (rank : 22)
Query Neighborhood Hits	48	Target Neighborhood Hits	49	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y6F7	Gene names	CDY2A, CDY2
Domain Architecture
Description	Testis-specific chromodomain protein Y 2.

CDY1_HUMAN
NC score	0.415496 (rank : 21)	θ value	4.1701e-05 (rank : 21)
Query Neighborhood Hits	48	Target Neighborhood Hits	48	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y6F8, O14600	Gene names	CDY1
Domain Architecture
Description	Testis-specific chromodomain protein Y 1.

SUV92_MOUSE
NC score	0.360703 (rank : 22)	θ value	2.44474e-05 (rank : 20)
Query Neighborhood Hits	48	Target Neighborhood Hits	59	Shared Neighborhood Hits	30
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV92_HUMAN
NC score	0.338432 (rank : 23)	θ value	0.00035302 (rank : 24)
Query Neighborhood Hits	48	Target Neighborhood Hits	54	Shared Neighborhood Hits	29
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV91_MOUSE
NC score	0.337890 (rank : 24)	θ value	0.00102713 (rank : 26)
Query Neighborhood Hits	48	Target Neighborhood Hits	69	Shared Neighborhood Hits	30
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SUV91_HUMAN
NC score	0.315026 (rank : 25)	θ value	0.00298849 (rank : 28)
Query Neighborhood Hits	48	Target Neighborhood Hits	63	Shared Neighborhood Hits	31
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

MPP8_HUMAN
NC score	0.243413 (rank : 26)	θ value	1.29631e-06 (rank : 17)
Query Neighborhood Hits	48	Target Neighborhood Hits	948	Shared Neighborhood Hits	35
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

CHD1_HUMAN
NC score	0.191595 (rank : 27)	θ value	0.00102713 (rank : 25)
Query Neighborhood Hits	48	Target Neighborhood Hits	337	Shared Neighborhood Hits	35
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
NC score	0.190064 (rank : 28)	θ value	0.00390308 (rank : 29)
Query Neighborhood Hits	48	Target Neighborhood Hits	266	Shared Neighborhood Hits	36
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD2_HUMAN
NC score	0.182163 (rank : 29)	θ value	0.00298849 (rank : 27)
Query Neighborhood Hits	48	Target Neighborhood Hits	360	Shared Neighborhood Hits	35
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

MS3L1_MOUSE
NC score	0.140002 (rank : 30)	θ value	0.125558 (rank : 31)
Query Neighborhood Hits	48	Target Neighborhood Hits	67	Shared Neighborhood Hits	18
SwissProt Accessions	Q9WVG9	Gene names	Msl3l1, Msl31
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

PECI_HUMAN
NC score	0.125818 (rank : 31)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	48	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	O75521, Q5JYK5, Q8N0X0, Q9BUE9, Q9H0T9, Q9NQH1, Q9NYH7, Q9UN55	Gene names	PECI, DRS1, HCA88
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (DBI-related protein 1) (DRS-1) (Hepatocellular carcinoma- associated antigen 88) (NY-REN-1 antigen).

PECI_MOUSE
NC score	0.125141 (rank : 32)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	48	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	Q9WUR2	Gene names	Peci
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase).

CHD3_HUMAN
NC score	0.106561 (rank : 33)	θ value	0.62314 (rank : 35)
Query Neighborhood Hits	48	Target Neighborhood Hits	397	Shared Neighborhood Hits	32
SwissProt Accessions	Q12873, Q9Y4I0	Gene names	CHD3
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 3 (EC 3.6.1.-) (ATP- dependent helicase CHD3) (CHD-3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc-finger helicase) (hZFH).

CHD4_HUMAN
NC score	0.095191 (rank : 34)	θ value	0.47712 (rank : 33)
Query Neighborhood Hits	48	Target Neighborhood Hits	365	Shared Neighborhood Hits	26
SwissProt Accessions	Q14839, Q8IXZ5	Gene names	CHD4
Domain Architecture
Description	Chromodomain helicase-DNA-binding protein 4 (EC 3.6.1.-) (ATP- dependent helicase CHD4) (CHD-4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta).

CHD4_MOUSE
NC score	0.094917 (rank : 35)	θ value	0.47712 (rank : 34)
Query Neighborhood Hits	48	Target Neighborhood Hits	408	Shared Neighborhood Hits	27
SwissProt Accessions	Q6PDQ2	Gene names	Chd4
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 4 (CHD-4).

CHD5_HUMAN
NC score	0.090622 (rank : 36)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	48	Target Neighborhood Hits	349	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TDI0, O75032, Q5TG89, Q9UFR9	Gene names	CHD5
Domain Architecture	No domain graphic available
Description	Chromodomain helicase-DNA-binding protein 5 (EC 3.6.1.-) (ATP- dependent helicase CHD5) (CHD-5).

ARI4A_HUMAN
NC score	0.087639 (rank : 37)	θ value	0.0431538 (rank : 30)
Query Neighborhood Hits	48	Target Neighborhood Hits	434	Shared Neighborhood Hits	14
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

ECH1_MOUSE
NC score	0.086644 (rank : 38)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	48	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	O35459, Q5M8P6	Gene names	Ech1
Domain Architecture
Description	Delta3,5-delta2,4-dienoyl-CoA isomerase, mitochondrial precursor (EC 5.3.3.-).

ECH1_HUMAN
NC score	0.084122 (rank : 39)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	48	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q13011, Q8WVX0, Q96EZ9	Gene names	ECH1
Domain Architecture
Description	Delta3,5-delta2,4-dienoyl-CoA isomerase, mitochondrial precursor (EC 5.3.3.-).

ECHM_MOUSE
NC score	0.082344 (rank : 40)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	48	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BH95, Q3TJK2, Q6GQS2, Q6PEN1, Q99LX7	Gene names	Echs1
Domain Architecture	No domain graphic available
Description	Enoyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.17) (Short chain enoyl-CoA hydratase) (SCEH) (Enoyl-CoA hydratase 1).

ECHM_HUMAN
NC score	0.081864 (rank : 41)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	48	Target Neighborhood Hits	23	Shared Neighborhood Hits	5
SwissProt Accessions	P30084, O00739, Q5VWY1, Q96H54	Gene names	ECHS1
Domain Architecture
Description	Enoyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.17) (Short chain enoyl-CoA hydratase) (SCEH) (Enoyl-CoA hydratase 1).

CHD6_HUMAN
NC score	0.080588 (rank : 42)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	48	Target Neighborhood Hits	342	Shared Neighborhood Hits	21
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

MS3L1_HUMAN
NC score	0.074096 (rank : 43)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	48	Target Neighborhood Hits	60	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N5Y2, Q9UG70, Q9Y5Z8	Gene names	MSL3L1
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

CHD9_HUMAN
NC score	0.072598 (rank : 44)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	48	Target Neighborhood Hits	343	Shared Neighborhood Hits	18
SwissProt Accessions	Q3L8U1, O15025, Q1WF12, Q6DTK9, Q9H9V7	Gene names	CHD9, KIAA0308, KISH2, PRIC320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Chromatin-related mesenchymal modulator) (CReMM) (Chromatin remodeling factor CHROM1) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha-interacting complex protein 320 kDa) (Kismet homolog 2).

CHD9_MOUSE
NC score	0.072547 (rank : 45)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	48	Target Neighborhood Hits	427	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BYH8, Q7TMV5, Q8BJG8, Q8BZJ2, Q8CHG8	Gene names	Chd9, Kiaa0308, Pric320
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 9 (EC 3.6.1.-) (ATP- dependent helicase CHD9) (CHD-9) (Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein) (PPAR-alpha- interacting complex protein 320 kDa).

CHD8_HUMAN
NC score	0.071292 (rank : 46)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	48	Target Neighborhood Hits	235	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

AUHM_MOUSE
NC score	0.066883 (rank : 47)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	48	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JLZ3, Q80YD7, Q8QZS0, Q9CY78, Q9D155	Gene names	Auh
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding enoyl-CoA hydratase) (muAUH).

AUMH_HUMAN
NC score	0.066104 (rank : 48)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	48	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q13825, Q8WUE4	Gene names	AUH
Domain Architecture
Description	Methylglutaconyl-CoA hydratase, mitochondrial precursor (EC 4.2.1.18) (AU-specific RNA-binding enoyl-CoA hydratase) (AU-binding protein/enoyl-CoA hydratase).

SMCA1_HUMAN
NC score	0.059874 (rank : 49)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	48	Target Neighborhood Hits	105	Shared Neighborhood Hits	8
SwissProt Accessions	P28370, Q5JV41, Q5JV42	Gene names	SMARCA1, SNF2L, SNF2L1
Domain Architecture
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1).

SMCA5_HUMAN
NC score	0.059682 (rank : 50)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	48	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	O60264	Gene names	SMARCA5, SNF2H, WCRF135
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin A5) (Sucrose nonfermenting protein 2 homolog) (hSNF2H).

SMCA5_MOUSE
NC score	0.059670 (rank : 51)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	48	Target Neighborhood Hits	80	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZW3, Q8C791, Q8CA22, Q8VDG1, Q925M9	Gene names	Smarca5, Snf2h
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (EC 3.6.1.-) (Sucrose nonfermenting protein 2 homolog) (mSnf2h).

SMCA1_MOUSE
NC score	0.059668 (rank : 52)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	48	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PGB8, Q8BSS1, Q91Y58	Gene names	Smarca1, Snf2l
Domain Architecture	No domain graphic available
Description	Probable global transcription activator SNF2L1 (EC 3.6.1.-) (Nucleosome remodeling factor subunit SNF2L) (ATP-dependent helicase SMARCA1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) (DNA-dependent ATPase SNF2L).

SMCA4_HUMAN
NC score	0.058729 (rank : 53)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	48	Target Neighborhood Hits	597	Shared Neighborhood Hits	12
SwissProt Accessions	P51532, O95052, Q9HBD3	Gene names	SMARCA4, BRG1, SNF2B, SNF2L4
Domain Architecture
Description	Probable global transcription activator SNF2L4 (EC 3.6.1.-) (ATP- dependent helicase SMARCA4) (SNF2-beta) (BRG-1 protein) (Mitotic growth and transcription activator) (Brahma protein homolog 1) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4).

SMRCD_MOUSE
NC score	0.057253 (rank : 54)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	48	Target Neighborhood Hits	96	Shared Neighborhood Hits	8
SwissProt Accessions	Q04692	Gene names	Smarcad1, Etl1, Kiaa1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase SMARCAD1) (Enhancer trap locus homolog 1) (Etl-1).

SMRCD_HUMAN
NC score	0.057113 (rank : 55)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	48	Target Neighborhood Hits	117	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H4L7, Q96SX1, Q9H017, Q9H860, Q9NPU9, Q9ULU7	Gene names	SMARCAD1, KIAA1122
Domain Architecture
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.1.-) (ATP- dependent helicase 1) (hHEL1).

ERCC6_HUMAN
NC score	0.057083 (rank : 56)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	48	Target Neighborhood Hits	247	Shared Neighborhood Hits	8
SwissProt Accessions	Q03468	Gene names	ERCC6, CSB
Domain Architecture
Description	DNA excision repair protein ERCC-6 (EC 3.6.1.-) (ATP-dependent helicase ERCC6) (Cockayne syndrome protein CSB).

SMCA2_HUMAN
NC score	0.056699 (rank : 57)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	48	Target Neighborhood Hits	503	Shared Neighborhood Hits	10
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

BTAF1_HUMAN
NC score	0.055431 (rank : 58)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	48	Target Neighborhood Hits	97	Shared Neighborhood Hits	8
SwissProt Accessions	O14981, O43578	Gene names	BTAF1, TAF172
Domain Architecture
Description	TATA-binding protein-associated factor 172 (EC 3.6.1.-) (ATP-dependent helicase BTAF1) (TBP-associated factor 172) (TAF-172) (TAF(II)170) (B- TFIID transcription factor-associated 170 kDa subunit).

EP400_MOUSE
NC score	0.055014 (rank : 59)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	48	Target Neighborhood Hits	592	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

RAD54_HUMAN
NC score	0.054338 (rank : 60)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	48	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	Q92698, Q6IUY3	Gene names	RAD54L, RAD54A
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (hRAD54) (hHR54).

RAD54_MOUSE
NC score	0.053953 (rank : 61)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	48	Target Neighborhood Hits	51	Shared Neighborhood Hits	8
SwissProt Accessions	P70270, Q8BSR5, Q8C2C4, Q8K3D4	Gene names	Rad54l, Rad54
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54-like (EC 3.6.1.-) (RAD54 homolog) (mRAD54) (mHR54).

INOC1_HUMAN
NC score	0.053822 (rank : 62)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	48	Target Neighborhood Hits	181	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ULG1, Q9NTG6	Gene names	INOC1, KIAA1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-) (hINO80).

INOC1_MOUSE
NC score	0.053822 (rank : 63)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	48	Target Neighborhood Hits	178	Shared Neighborhood Hits	8
SwissProt Accessions	Q6ZPV2, Q6P7V0, Q6PCP1, Q8C9T7	Gene names	Inoc1, Kiaa1259
Domain Architecture	No domain graphic available
Description	Putative DNA helicase INO80 complex homolog 1 (EC 3.6.1.-).

RA54B_HUMAN
NC score	0.053742 (rank : 64)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	48	Target Neighborhood Hits	54	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y620	Gene names	RAD54B
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

RA54B_MOUSE
NC score	0.053339 (rank : 65)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	48	Target Neighborhood Hits	59	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PFE3	Gene names	Rad54b
Domain Architecture	No domain graphic available
Description	DNA repair and recombination protein RAD54B (EC 3.6.1.-) (RAD54 homolog B).

ECHA_HUMAN
NC score	0.052984 (rank : 66)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	48	Target Neighborhood Hits	28	Shared Neighborhood Hits	5
SwissProt Accessions	P40939, Q16679, Q96GT7	Gene names	HADHA, HADH
Domain Architecture
Description	Trifunctional enzyme subunit alpha, mitochondrial precursor (TP-alpha) (78 kDa gastrin-binding protein) [Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)].

SETD2_HUMAN
NC score	0.051931 (rank : 67)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	48	Target Neighborhood Hits	412	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

EP400_HUMAN
NC score	0.050226 (rank : 68)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	48	Target Neighborhood Hits	556	Shared Neighborhood Hits	12
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

PLIN_HUMAN
NC score	0.017419 (rank : 69)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	48	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	O60240, Q8N5Y6	Gene names	PLIN
Domain Architecture
Description	Perilipin (PERI) (Lipid droplet-associated protein).

K1802_MOUSE
NC score	0.017389 (rank : 70)	θ value	0.279714 (rank : 32)
Query Neighborhood Hits	48	Target Neighborhood Hits	1596	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

ESPL1_HUMAN
NC score	0.016203 (rank : 71)	θ value	5.27518 (rank : 41)
Query Neighborhood Hits	48	Target Neighborhood Hits	95	Shared Neighborhood Hits	3
SwissProt Accessions	Q14674	Gene names	ESPL1, ESP1, KIAA0165
Domain Architecture
Description	Separin (EC 3.4.22.49) (Separase) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein).

NDF1_HUMAN
NC score	0.016065 (rank : 72)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	48	Target Neighborhood Hits	186	Shared Neighborhood Hits	5
SwissProt Accessions	Q13562, O00343, Q13340, Q5U095, Q96TH0, Q99455, Q9UEC8	Gene names	NEUROD1, NEUROD
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1) (NeuroD).

NDF2_HUMAN
NC score	0.015117 (rank : 73)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	48	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	Q15784, Q8TBI7, Q9UQC6	Gene names	NEUROD2, NDRF
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF2_MOUSE
NC score	0.014735 (rank : 74)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	48	Target Neighborhood Hits	111	Shared Neighborhood Hits	5
SwissProt Accessions	Q62414, Q61952, Q925V5	Gene names	Neurod2, Ndrf
Domain Architecture
Description	Neurogenic differentiation factor 2 (NeuroD2) (NeuroD-related factor) (NDRF).

NDF1_MOUSE
NC score	0.014570 (rank : 75)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	48	Target Neighborhood Hits	209	Shared Neighborhood Hits	5
SwissProt Accessions	Q60867, Q545N9, Q60897	Gene names	Neurod1, Neurod
Domain Architecture
Description	Neurogenic differentiation factor 1 (NeuroD1).

DUS11_HUMAN
NC score	0.011766 (rank : 76)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	48	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	O75319, Q6AI47, Q9BWE3	Gene names	DUSP11, PIR1
Domain Architecture
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

MYO15_MOUSE
NC score	0.006940 (rank : 77)	θ value	3.0926 (rank : 39)
Query Neighborhood Hits	48	Target Neighborhood Hits	467	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

PHLB1_HUMAN
NC score	0.006316 (rank : 78)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	48	Target Neighborhood Hits	1038	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UU1, O75133, Q4KMF8, Q8TEQ2	Gene names	PHLDB1, DLNB07, KIAA0638, LL5A
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).

AHI1_MOUSE
NC score	0.002630 (rank : 79)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	48	Target Neighborhood Hits	496	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K3E5, Q7TNV2, Q9CVY1	Gene names	Ahi1
Domain Architecture	No domain graphic available
Description	Jouberin (Abelson helper integration site 1 protein) (AHI-1).