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Network neighborhood for query Sequence : MS3L1_MOUSE

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MS3L1_MOUSE
SwissProt Accessions	Q9WVG9	Gene names	Msl3l1, Msl31
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MS3L1_HUMAN
θ value	0 (rank : 1)	NC score	0.981001 (rank : 2)
Query Neighborhood Hits	67	Target Neighborhood Hits	60	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N5Y2, Q9UG70, Q9Y5Z8	Gene names	MSL3L1
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

MS3L1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WVG9	Gene names	Msl3l1, Msl31
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

MO4L1_HUMAN
θ value	5.8054e-15 (rank : 3)	NC score	0.522007 (rank : 3)
Query Neighborhood Hits	67	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBU8, O95899, Q5QTS1, Q6NVX8, Q86YT7, Q9HBP6, Q9NSW5	Gene names	MORF4L1, MRG15
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (MSL3-1 protein).

MO4L1_MOUSE
θ value	5.8054e-15 (rank : 4)	NC score	0.521892 (rank : 4)
Query Neighborhood Hits	67	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	P60762, Q8BNY9, Q99MQ0	Gene names	Morf4l1, Mrg15, Tex189
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (Testis-expressed gene 189 protein).

MO4L2_MOUSE
θ value	1.69304e-06 (rank : 5)	NC score	0.430745 (rank : 5)
Query Neighborhood Hits	67	Target Neighborhood Hits	86	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R0Q4, Q3UL62, Q6DIB1, Q6ZQK7, Q8C201, Q8C6C2	Gene names	Morf4l2, Kiaa0026, Sid393
Domain Architecture	No domain graphic available
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (Sid 393).

MO4L2_HUMAN
θ value	3.77169e-06 (rank : 6)	NC score	0.427040 (rank : 6)
Query Neighborhood Hits	67	Target Neighborhood Hits	90	Shared Neighborhood Hits	11
SwissProt Accessions	Q15014, Q567V0, Q8J026	Gene names	MORF4L2, KIAA0026, MRGX
Domain Architecture
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein).

MORF4_HUMAN
θ value	0.000270298 (rank : 7)	NC score	0.416410 (rank : 7)
Query Neighborhood Hits	67	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y690	Gene names	MORF4
Domain Architecture
Description	Transcription factor-like protein MORF4 (Mortality factor 4) (Cellular senescence-related protein 1) (SEN1).

CBX2_HUMAN
θ value	0.0113563 (rank : 8)	NC score	0.131565 (rank : 10)
Query Neighborhood Hits	67	Target Neighborhood Hits	264	Shared Neighborhood Hits	19
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

MYST1_HUMAN
θ value	0.0252991 (rank : 9)	NC score	0.091633 (rank : 20)
Query Neighborhood Hits	67	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H7Z6, Q659G0, Q7LC17, Q8IY59, Q8WYB4, Q8WZ14, Q9HAC5, Q9NR35	Gene names	MYST1, MOF
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (hMOF).

MYST1_MOUSE
θ value	0.0252991 (rank : 10)	NC score	0.091589 (rank : 21)
Query Neighborhood Hits	67	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D1P2, Q3UIY0, Q8BJ69, Q8BJ76, Q8CI73	Gene names	Myst1, Mof
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1).

ARI4A_HUMAN
θ value	0.0330416 (rank : 11)	NC score	0.122292 (rank : 11)
Query Neighborhood Hits	67	Target Neighborhood Hits	434	Shared Neighborhood Hits	26
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

CBX2_MOUSE
θ value	0.0563607 (rank : 12)	NC score	0.133323 (rank : 9)
Query Neighborhood Hits	67	Target Neighborhood Hits	119	Shared Neighborhood Hits	19
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

CHD1_MOUSE
θ value	0.0736092 (rank : 13)	NC score	0.045474 (rank : 40)
Query Neighborhood Hits	67	Target Neighborhood Hits	266	Shared Neighborhood Hits	20
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

PO6F2_HUMAN
θ value	0.0961366 (rank : 14)	NC score	0.061036 (rank : 26)
Query Neighborhood Hits	67	Target Neighborhood Hits	618	Shared Neighborhood Hits	12
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PO6F2_MOUSE
θ value	0.0961366 (rank : 15)	NC score	0.060666 (rank : 27)
Query Neighborhood Hits	67	Target Neighborhood Hits	639	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

CBX7_HUMAN
θ value	0.125558 (rank : 16)	NC score	0.140002 (rank : 8)
Query Neighborhood Hits	67	Target Neighborhood Hits	48	Shared Neighborhood Hits	18
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

WDHD1_MOUSE
θ value	0.163984 (rank : 17)	NC score	0.035173 (rank : 45)
Query Neighborhood Hits	67	Target Neighborhood Hits	414	Shared Neighborhood Hits	7
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

CDYL1_HUMAN
θ value	0.21417 (rank : 18)	NC score	0.116106 (rank : 12)
Query Neighborhood Hits	67	Target Neighborhood Hits	92	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y232	Gene names	CDYL, CDYL1
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CDY1_HUMAN
θ value	0.279714 (rank : 19)	NC score	0.108925 (rank : 15)
Query Neighborhood Hits	67	Target Neighborhood Hits	48	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6F8, O14600	Gene names	CDY1
Domain Architecture
Description	Testis-specific chromodomain protein Y 1.

CDY2_HUMAN
θ value	0.279714 (rank : 20)	NC score	0.109311 (rank : 14)
Query Neighborhood Hits	67	Target Neighborhood Hits	49	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6F7	Gene names	CDY2A, CDY2
Domain Architecture
Description	Testis-specific chromodomain protein Y 2.

CDYL_MOUSE
θ value	0.47712 (rank : 21)	NC score	0.107156 (rank : 16)
Query Neighborhood Hits	67	Target Neighborhood Hits	69	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WTK2	Gene names	Cdyl
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

FA47A_HUMAN
θ value	0.62314 (rank : 22)	NC score	0.053888 (rank : 33)
Query Neighborhood Hits	67	Target Neighborhood Hits	451	Shared Neighborhood Hits	13
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

PHF20_MOUSE
θ value	0.62314 (rank : 23)	NC score	0.050100 (rank : 38)
Query Neighborhood Hits	67	Target Neighborhood Hits	513	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

CHD1_HUMAN
θ value	0.813845 (rank : 24)	NC score	0.045366 (rank : 41)
Query Neighborhood Hits	67	Target Neighborhood Hits	337	Shared Neighborhood Hits	27
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

PCLO_HUMAN
θ value	0.813845 (rank : 25)	NC score	0.033871 (rank : 47)
Query Neighborhood Hits	67	Target Neighborhood Hits	2046	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

CDYL2_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.096044 (rank : 19)
Query Neighborhood Hits	67	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N8U2	Gene names	CDYL2
Domain Architecture
Description	Chromodomain Y-like protein 2 (CDY-like 2).

MDC1_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.030271 (rank : 50)
Query Neighborhood Hits	67	Target Neighborhood Hits	1446	Shared Neighborhood Hits	25
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

CBX7_MOUSE
θ value	1.81305 (rank : 28)	NC score	0.109342 (rank : 13)
Query Neighborhood Hits	67	Target Neighborhood Hits	38	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

GCKR_MOUSE
θ value	1.81305 (rank : 29)	NC score	0.034495 (rank : 46)
Query Neighborhood Hits	67	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q91X44	Gene names	Gckr
Domain Architecture	No domain graphic available
Description	Glucokinase regulatory protein (Glucokinase regulator).

MARK2_MOUSE
θ value	1.81305 (rank : 30)	NC score	0.005144 (rank : 74)
Query Neighborhood Hits	67	Target Neighborhood Hits	1018	Shared Neighborhood Hits	10
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

NACAM_MOUSE
θ value	1.81305 (rank : 31)	NC score	0.027542 (rank : 53)
Query Neighborhood Hits	67	Target Neighborhood Hits	1866	Shared Neighborhood Hits	28
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SOX13_HUMAN
θ value	1.81305 (rank : 32)	NC score	0.025211 (rank : 55)
Query Neighborhood Hits	67	Target Neighborhood Hits	464	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

NIPBL_HUMAN
θ value	2.36792 (rank : 33)	NC score	0.038136 (rank : 44)
Query Neighborhood Hits	67	Target Neighborhood Hits	1311	Shared Neighborhood Hits	27
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

NPBL_MOUSE
θ value	2.36792 (rank : 34)	NC score	0.044881 (rank : 42)
Query Neighborhood Hits	67	Target Neighborhood Hits	1041	Shared Neighborhood Hits	24
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

PLEC1_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.008759 (rank : 72)
Query Neighborhood Hits	67	Target Neighborhood Hits	1326	Shared Neighborhood Hits	15
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

PKHA5_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.028993 (rank : 52)
Query Neighborhood Hits	67	Target Neighborhood Hits	455	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

TRIPC_HUMAN
θ value	3.0926 (rank : 37)	NC score	0.019628 (rank : 59)
Query Neighborhood Hits	67	Target Neighborhood Hits	319	Shared Neighborhood Hits	12
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

CBX8_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.097606 (rank : 17)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HC52, Q96H39, Q9NR07	Gene names	CBX8, PC3, RC1
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1).

CBX8_MOUSE
θ value	4.03905 (rank : 39)	NC score	0.096749 (rank : 18)
Query Neighborhood Hits	67	Target Neighborhood Hits	46	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QXV1	Gene names	Cbx8, Pc3
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (mPc3).

ELK1_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.017737 (rank : 60)
Query Neighborhood Hits	67	Target Neighborhood Hits	110	Shared Neighborhood Hits	5
SwissProt Accessions	P41969	Gene names	Elk1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

ICB1_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.023297 (rank : 56)
Query Neighborhood Hits	67	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

KI21A_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.006517 (rank : 73)
Query Neighborhood Hits	67	Target Neighborhood Hits	1317	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

NUMA1_HUMAN
θ value	4.03905 (rank : 43)	NC score	0.009300 (rank : 69)
Query Neighborhood Hits	67	Target Neighborhood Hits	1523	Shared Neighborhood Hits	18
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

REM1_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.010194 (rank : 66)
Query Neighborhood Hits	67	Target Neighborhood Hits	247	Shared Neighborhood Hits	3
SwissProt Accessions	O75628, Q9NP57	Gene names	REM1, GES, REM
Domain Architecture
Description	GTP-binding protein REM 1 (Rad and Gem-like GTP-binding protein 1) (GTPase-regulating endothelial cell sprouting).

SRRM2_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.056780 (rank : 28)
Query Neighborhood Hits	67	Target Neighborhood Hits	1296	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

TTF1_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.048986 (rank : 39)
Query Neighborhood Hits	67	Target Neighborhood Hits	277	Shared Neighborhood Hits	15
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

AFF2_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.027439 (rank : 54)
Query Neighborhood Hits	67	Target Neighborhood Hits	218	Shared Neighborhood Hits	9
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

AFF4_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.033117 (rank : 48)
Query Neighborhood Hits	67	Target Neighborhood Hits	611	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

ANRA2_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.009857 (rank : 68)
Query Neighborhood Hits	67	Target Neighborhood Hits	287	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

CCD45_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.015694 (rank : 63)
Query Neighborhood Hits	67	Target Neighborhood Hits	663	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

CD244_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.040315 (rank : 43)
Query Neighborhood Hits	67	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZW8, Q96T47, Q9NQD2, Q9NQD3, Q9Y288	Gene names	CD244, 2B4
Domain Architecture
Description	Natural killer cell receptor 2B4 precursor (NKR2B4) (NK cell type I receptor protein 2B4) (h2B4) (CD244 antigen) (NK cell activation- inducing ligand) (NAIL).

NBN_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.023080 (rank : 57)
Query Neighborhood Hits	67	Target Neighborhood Hits	226	Shared Neighborhood Hits	8
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

TP53B_MOUSE
θ value	5.27518 (rank : 53)	NC score	0.032907 (rank : 49)
Query Neighborhood Hits	67	Target Neighborhood Hits	644	Shared Neighborhood Hits	15
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

AFF3_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.029328 (rank : 51)
Query Neighborhood Hits	67	Target Neighborhood Hits	190	Shared Neighborhood Hits	11
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

ANRA2_HUMAN
θ value	6.88961 (rank : 55)	NC score	0.009040 (rank : 71)
Query Neighborhood Hits	67	Target Neighborhood Hits	288	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

CADH3_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.002868 (rank : 75)
Query Neighborhood Hits	67	Target Neighborhood Hits	159	Shared Neighborhood Hits	2
SwissProt Accessions	P22223	Gene names	CDH3, CDHP
Domain Architecture
Description	Cadherin-3 precursor (Placental-cadherin) (P-cadherin).

CBX4_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.085736 (rank : 22)
Query Neighborhood Hits	67	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	O00257, Q96C04	Gene names	CBX4
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (hPc2).

CBX4_MOUSE
θ value	6.88961 (rank : 58)	NC score	0.085615 (rank : 23)
Query Neighborhood Hits	67	Target Neighborhood Hits	64	Shared Neighborhood Hits	18
SwissProt Accessions	O55187	Gene names	Cbx4, Pc2
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (mPc2).

K1688_HUMAN
θ value	6.88961 (rank : 59)	NC score	0.015714 (rank : 62)
Query Neighborhood Hits	67	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

MRCKB_MOUSE
θ value	6.88961 (rank : 60)	NC score	0.001515 (rank : 76)
Query Neighborhood Hits	67	Target Neighborhood Hits	2180	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

OCRL_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.011702 (rank : 65)
Query Neighborhood Hits	67	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

SRRM2_MOUSE
θ value	6.88961 (rank : 62)	NC score	0.051443 (rank : 36)
Query Neighborhood Hits	67	Target Neighborhood Hits	1470	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

AKA11_HUMAN
θ value	8.99809 (rank : 63)	NC score	0.017289 (rank : 61)
Query Neighborhood Hits	67	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKA4, O75124, Q9NUK7	Gene names	AKAP11, AKAP220, KIAA0629
Domain Architecture
Description	A-kinase anchor protein 11 (Protein kinase A-anchoring protein 11) (PRKA11) (A kinase anchor protein 220 kDa) (AKAP 220) (hAKAP220).

ASXL1_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.022258 (rank : 58)
Query Neighborhood Hits	67	Target Neighborhood Hits	260	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

IQGA2_HUMAN
θ value	8.99809 (rank : 65)	NC score	0.009188 (rank : 70)
Query Neighborhood Hits	67	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	Q13576	Gene names	IQGAP2
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP2.

MILK1_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.013949 (rank : 64)
Query Neighborhood Hits	67	Target Neighborhood Hits	788	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

MY18B_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.010106 (rank : 67)
Query Neighborhood Hits	67	Target Neighborhood Hits	1299	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

CBX1_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.055745 (rank : 31)
Query Neighborhood Hits	67	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.055745 (rank : 32)
Query Neighborhood Hits	67	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX3_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.052251 (rank : 35)
Query Neighborhood Hits	67	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX3_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.052302 (rank : 34)
Query Neighborhood Hits	67	Target Neighborhood Hits	39	Shared Neighborhood Hits	15
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CBX5_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.056726 (rank : 29)
Query Neighborhood Hits	67	Target Neighborhood Hits	70	Shared Neighborhood Hits	17
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.056580 (rank : 30)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	15
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CBX6_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.074324 (rank : 24)
Query Neighborhood Hits	67	Target Neighborhood Hits	104	Shared Neighborhood Hits	19
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX6_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.073617 (rank : 25)
Query Neighborhood Hits	67	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	Q9DBY5, Q8BZH5	Gene names	Cbx6
Domain Architecture
Description	Chromobox protein homolog 6.

PECI_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.050135 (rank : 37)
Query Neighborhood Hits	67	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	O75521, Q5JYK5, Q8N0X0, Q9BUE9, Q9H0T9, Q9NQH1, Q9NYH7, Q9UN55	Gene names	PECI, DRS1, HCA88
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (DBI-related protein 1) (DRS-1) (Hepatocellular carcinoma- associated antigen 88) (NY-REN-1 antigen).

Hits sorted by NC score

MS3L1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	67
SwissProt Accessions	Q9WVG9	Gene names	Msl3l1, Msl31
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

MS3L1_HUMAN
NC score	0.981001 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	67	Target Neighborhood Hits	60	Shared Neighborhood Hits	36
SwissProt Accessions	Q8N5Y2, Q9UG70, Q9Y5Z8	Gene names	MSL3L1
Domain Architecture
Description	Male-specific lethal 3-like 1 (MSL3-like 1) (Male-specific lethal-3 homolog 1).

MO4L1_HUMAN
NC score	0.522007 (rank : 3)	θ value	5.8054e-15 (rank : 3)
Query Neighborhood Hits	67	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBU8, O95899, Q5QTS1, Q6NVX8, Q86YT7, Q9HBP6, Q9NSW5	Gene names	MORF4L1, MRG15
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (MSL3-1 protein).

MO4L1_MOUSE
NC score	0.521892 (rank : 4)	θ value	5.8054e-15 (rank : 4)
Query Neighborhood Hits	67	Target Neighborhood Hits	51	Shared Neighborhood Hits	10
SwissProt Accessions	P60762, Q8BNY9, Q99MQ0	Gene names	Morf4l1, Mrg15, Tex189
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (Testis-expressed gene 189 protein).

MO4L2_MOUSE
NC score	0.430745 (rank : 5)	θ value	1.69304e-06 (rank : 5)
Query Neighborhood Hits	67	Target Neighborhood Hits	86	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R0Q4, Q3UL62, Q6DIB1, Q6ZQK7, Q8C201, Q8C6C2	Gene names	Morf4l2, Kiaa0026, Sid393
Domain Architecture	No domain graphic available
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (Sid 393).

MO4L2_HUMAN
NC score	0.427040 (rank : 6)	θ value	3.77169e-06 (rank : 6)
Query Neighborhood Hits	67	Target Neighborhood Hits	90	Shared Neighborhood Hits	11
SwissProt Accessions	Q15014, Q567V0, Q8J026	Gene names	MORF4L2, KIAA0026, MRGX
Domain Architecture
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein).

MORF4_HUMAN
NC score	0.416410 (rank : 7)	θ value	0.000270298 (rank : 7)
Query Neighborhood Hits	67	Target Neighborhood Hits	15	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y690	Gene names	MORF4
Domain Architecture
Description	Transcription factor-like protein MORF4 (Mortality factor 4) (Cellular senescence-related protein 1) (SEN1).

CBX7_HUMAN
NC score	0.140002 (rank : 8)	θ value	0.125558 (rank : 16)
Query Neighborhood Hits	67	Target Neighborhood Hits	48	Shared Neighborhood Hits	18
SwissProt Accessions	O95931, Q86T17	Gene names	CBX7
Domain Architecture
Description	Chromobox protein homolog 7.

CBX2_MOUSE
NC score	0.133323 (rank : 9)	θ value	0.0563607 (rank : 12)
Query Neighborhood Hits	67	Target Neighborhood Hits	119	Shared Neighborhood Hits	19
SwissProt Accessions	P30658, O35731, Q8CIA0	Gene names	Cbx2, M33
Domain Architecture
Description	Chromobox protein homolog 2 (Modifier 3 protein) (M33).

CBX2_HUMAN
NC score	0.131565 (rank : 10)	θ value	0.0113563 (rank : 8)
Query Neighborhood Hits	67	Target Neighborhood Hits	264	Shared Neighborhood Hits	19
SwissProt Accessions	Q14781, Q9BTB1	Gene names	CBX2
Domain Architecture	No domain graphic available
Description	Chromobox protein homolog 2.

ARI4A_HUMAN
NC score	0.122292 (rank : 11)	θ value	0.0330416 (rank : 11)
Query Neighborhood Hits	67	Target Neighborhood Hits	434	Shared Neighborhood Hits	26
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

CDYL1_HUMAN
NC score	0.116106 (rank : 12)	θ value	0.21417 (rank : 18)
Query Neighborhood Hits	67	Target Neighborhood Hits	92	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y232	Gene names	CDYL, CDYL1
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CBX7_MOUSE
NC score	0.109342 (rank : 13)	θ value	1.81305 (rank : 28)
Query Neighborhood Hits	67	Target Neighborhood Hits	38	Shared Neighborhood Hits	17
SwissProt Accessions	Q8VDS3	Gene names	Cbx7, D15Ertd417e
Domain Architecture
Description	Chromobox protein homolog 7.

CDY2_HUMAN
NC score	0.109311 (rank : 14)	θ value	0.279714 (rank : 20)
Query Neighborhood Hits	67	Target Neighborhood Hits	49	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6F7	Gene names	CDY2A, CDY2
Domain Architecture
Description	Testis-specific chromodomain protein Y 2.

CDY1_HUMAN
NC score	0.108925 (rank : 15)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	67	Target Neighborhood Hits	48	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6F8, O14600	Gene names	CDY1
Domain Architecture
Description	Testis-specific chromodomain protein Y 1.

CDYL_MOUSE
NC score	0.107156 (rank : 16)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	67	Target Neighborhood Hits	69	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WTK2	Gene names	Cdyl
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

CBX8_HUMAN
NC score	0.097606 (rank : 17)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	19
SwissProt Accessions	Q9HC52, Q96H39, Q9NR07	Gene names	CBX8, PC3, RC1
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1).

CBX8_MOUSE
NC score	0.096749 (rank : 18)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	67	Target Neighborhood Hits	46	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QXV1	Gene names	Cbx8, Pc3
Domain Architecture
Description	Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (mPc3).

CDYL2_HUMAN
NC score	0.096044 (rank : 19)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	67	Target Neighborhood Hits	53	Shared Neighborhood Hits	16
SwissProt Accessions	Q8N8U2	Gene names	CDYL2
Domain Architecture
Description	Chromodomain Y-like protein 2 (CDY-like 2).

MYST1_HUMAN
NC score	0.091633 (rank : 20)	θ value	0.0252991 (rank : 9)
Query Neighborhood Hits	67	Target Neighborhood Hits	53	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H7Z6, Q659G0, Q7LC17, Q8IY59, Q8WYB4, Q8WZ14, Q9HAC5, Q9NR35	Gene names	MYST1, MOF
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (hMOF).

MYST1_MOUSE
NC score	0.091589 (rank : 21)	θ value	0.0252991 (rank : 10)
Query Neighborhood Hits	67	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D1P2, Q3UIY0, Q8BJ69, Q8BJ76, Q8CI73	Gene names	Myst1, Mof
Domain Architecture	No domain graphic available
Description	Probable histone acetyltransferase MYST1 (EC 2.3.1.48) (MYST protein 1) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1).

CBX4_HUMAN
NC score	0.085736 (rank : 22)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	67	Target Neighborhood Hits	68	Shared Neighborhood Hits	18
SwissProt Accessions	O00257, Q96C04	Gene names	CBX4
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (hPc2).

CBX4_MOUSE
NC score	0.085615 (rank : 23)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	67	Target Neighborhood Hits	64	Shared Neighborhood Hits	18
SwissProt Accessions	O55187	Gene names	Cbx4, Pc2
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (mPc2).

CBX6_HUMAN
NC score	0.074324 (rank : 24)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	67	Target Neighborhood Hits	104	Shared Neighborhood Hits	19
SwissProt Accessions	O95503, Q96EM5	Gene names	CBX6
Domain Architecture
Description	Chromobox protein homolog 6.

CBX6_MOUSE
NC score	0.073617 (rank : 25)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	67	Target Neighborhood Hits	50	Shared Neighborhood Hits	16
SwissProt Accessions	Q9DBY5, Q8BZH5	Gene names	Cbx6
Domain Architecture
Description	Chromobox protein homolog 6.

PO6F2_HUMAN
NC score	0.061036 (rank : 26)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	67	Target Neighborhood Hits	618	Shared Neighborhood Hits	12
SwissProt Accessions	P78424, P78425, Q75ME8, Q86UM6, Q9UDS7	Gene names	POU6F2, RPF1
Domain Architecture
Description	POU domain, class 6, transcription factor 2 (Retina-derived POU-domain factor 1) (RPF-1).

PO6F2_MOUSE
NC score	0.060666 (rank : 27)	θ value	0.0961366 (rank : 15)
Query Neighborhood Hits	67	Target Neighborhood Hits	639	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BJI4	Gene names	Pou6f2
Domain Architecture	No domain graphic available
Description	POU domain, class 6, transcription factor 2.

SRRM2_HUMAN
NC score	0.056780 (rank : 28)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	67	Target Neighborhood Hits	1296	Shared Neighborhood Hits	35
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

CBX5_HUMAN
NC score	0.056726 (rank : 29)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	67	Target Neighborhood Hits	70	Shared Neighborhood Hits	17
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
NC score	0.056580 (rank : 30)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	67	Target Neighborhood Hits	67	Shared Neighborhood Hits	15
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CBX1_HUMAN
NC score	0.055745 (rank : 31)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	67	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.055745 (rank : 32)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	67	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

FA47A_HUMAN
NC score	0.053888 (rank : 33)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	67	Target Neighborhood Hits	451	Shared Neighborhood Hits	13
SwissProt Accessions	Q5JRC9, Q8TAA0	Gene names	FAM47A
Domain Architecture	No domain graphic available
Description	Protein FAM47A.

CBX3_MOUSE
NC score	0.052302 (rank : 34)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	67	Target Neighborhood Hits	39	Shared Neighborhood Hits	15
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CBX3_HUMAN
NC score	0.052251 (rank : 35)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	67	Target Neighborhood Hits	36	Shared Neighborhood Hits	15
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

SRRM2_MOUSE
NC score	0.051443 (rank : 36)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	67	Target Neighborhood Hits	1470	Shared Neighborhood Hits	34
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PECI_HUMAN
NC score	0.050135 (rank : 37)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	67	Target Neighborhood Hits	26	Shared Neighborhood Hits	5
SwissProt Accessions	O75521, Q5JYK5, Q8N0X0, Q9BUE9, Q9H0T9, Q9NQH1, Q9NYH7, Q9UN55	Gene names	PECI, DRS1, HCA88
Domain Architecture
Description	Peroxisomal 3,2-trans-enoyl-CoA isomerase (EC 5.3.3.8) (Dodecenoyl-CoA isomerase) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (DBI-related protein 1) (DRS-1) (Hepatocellular carcinoma- associated antigen 88) (NY-REN-1 antigen).

PHF20_MOUSE
NC score	0.050100 (rank : 38)	θ value	0.62314 (rank : 23)
Query Neighborhood Hits	67	Target Neighborhood Hits	513	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

TTF1_MOUSE
NC score	0.048986 (rank : 39)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	67	Target Neighborhood Hits	277	Shared Neighborhood Hits	15
SwissProt Accessions	Q62187, Q9JKK5	Gene names	Ttf1
Domain Architecture	No domain graphic available
Description	Transcription termination factor 1 (TTF-1) (TTF-I) (mTFF-I) (RNA polymerase I termination factor).

CHD1_MOUSE
NC score	0.045474 (rank : 40)	θ value	0.0736092 (rank : 13)
Query Neighborhood Hits	67	Target Neighborhood Hits	266	Shared Neighborhood Hits	20
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_HUMAN
NC score	0.045366 (rank : 41)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	67	Target Neighborhood Hits	337	Shared Neighborhood Hits	27
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

NPBL_MOUSE
NC score	0.044881 (rank : 42)	θ value	2.36792 (rank : 34)
Query Neighborhood Hits	67	Target Neighborhood Hits	1041	Shared Neighborhood Hits	24
SwissProt Accessions	Q6KCD5, Q6KC78, Q7TNS4, Q8BKV4, Q8CES9, Q9CUC6	Gene names	Nipbl
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin homolog) (SCC2 homolog).

CD244_HUMAN
NC score	0.040315 (rank : 43)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	67	Target Neighborhood Hits	72	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BZW8, Q96T47, Q9NQD2, Q9NQD3, Q9Y288	Gene names	CD244, 2B4
Domain Architecture
Description	Natural killer cell receptor 2B4 precursor (NKR2B4) (NK cell type I receptor protein 2B4) (h2B4) (CD244 antigen) (NK cell activation- inducing ligand) (NAIL).

NIPBL_HUMAN
NC score	0.038136 (rank : 44)	θ value	2.36792 (rank : 33)
Query Neighborhood Hits	67	Target Neighborhood Hits	1311	Shared Neighborhood Hits	27
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

WDHD1_MOUSE
NC score	0.035173 (rank : 45)	θ value	0.163984 (rank : 17)
Query Neighborhood Hits	67	Target Neighborhood Hits	414	Shared Neighborhood Hits	7
SwissProt Accessions	P59328, Q6P408	Gene names	Wdhd1, And1
Domain Architecture	No domain graphic available
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

GCKR_MOUSE
NC score	0.034495 (rank : 46)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	67	Target Neighborhood Hits	5	Shared Neighborhood Hits	2
SwissProt Accessions	Q91X44	Gene names	Gckr
Domain Architecture	No domain graphic available
Description	Glucokinase regulatory protein (Glucokinase regulator).

PCLO_HUMAN
NC score	0.033871 (rank : 47)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	67	Target Neighborhood Hits	2046	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

AFF4_HUMAN
NC score	0.033117 (rank : 48)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	67	Target Neighborhood Hits	611	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UHB7, Q498B2, Q59FB3, Q6P592, Q8TDR1, Q9P0E4	Gene names	AFF4, AF5Q31, MCEF
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4 (ALL1-fused gene from chromosome 5q31) (Major CDK9 elongation factor-associated protein).

TP53B_MOUSE
NC score	0.032907 (rank : 49)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	67	Target Neighborhood Hits	644	Shared Neighborhood Hits	15
SwissProt Accessions	P70399, Q68FD0, Q8CI97, Q91YC9	Gene names	Tp53bp1, Trp53bp1
Domain Architecture	No domain graphic available
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

MDC1_HUMAN
NC score	0.030271 (rank : 50)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	67	Target Neighborhood Hits	1446	Shared Neighborhood Hits	25
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

AFF3_HUMAN
NC score	0.029328 (rank : 51)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	67	Target Neighborhood Hits	190	Shared Neighborhood Hits	11
SwissProt Accessions	P51826	Gene names	AFF3, LAF4
Domain Architecture
Description	AF4/FMR2 family member 3 (Protein LAF-4) (Lymphoid nuclear protein related to AF4).

PKHA5_HUMAN
NC score	0.028993 (rank : 52)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	67	Target Neighborhood Hits	455	Shared Neighborhood Hits	12
SwissProt Accessions	Q9HAU0, Q8N3K6, Q96DY9, Q9BVR4, Q9C0H7, Q9H924, Q9NVK8	Gene names	PLEKHA5, KIAA1686, PEPP2
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 5 (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2).

NACAM_MOUSE
NC score	0.027542 (rank : 53)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	67	Target Neighborhood Hits	1866	Shared Neighborhood Hits	28
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

AFF2_HUMAN
NC score	0.027439 (rank : 54)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	67	Target Neighborhood Hits	218	Shared Neighborhood Hits	9
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

SOX13_HUMAN
NC score	0.025211 (rank : 55)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	67	Target Neighborhood Hits	464	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UN79, O95275, O95826, Q9UHW7	Gene names	SOX13
Domain Architecture
Description	SOX-13 protein (Type 1 diabetes autoantigen ICA12) (Islet cell antigen 12).

ICB1_MOUSE
NC score	0.023297 (rank : 56)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	67	Target Neighborhood Hits	69	Shared Neighborhood Hits	7
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

NBN_HUMAN
NC score	0.023080 (rank : 57)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	67	Target Neighborhood Hits	226	Shared Neighborhood Hits	8
SwissProt Accessions	O60934, O60672, Q32NF7, Q53FM6, Q63HR6, Q7LDM2	Gene names	NBN, NBS, NBS1, P95
Domain Architecture	No domain graphic available
Description	Nibrin (Nijmegen breakage syndrome protein 1) (Cell cycle regulatory protein p95).

ASXL1_HUMAN
NC score	0.022258 (rank : 58)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	67	Target Neighborhood Hits	260	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

TRIPC_HUMAN
NC score	0.019628 (rank : 59)	θ value	3.0926 (rank : 37)
Query Neighborhood Hits	67	Target Neighborhood Hits	319	Shared Neighborhood Hits	12
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

ELK1_MOUSE
NC score	0.017737 (rank : 60)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	67	Target Neighborhood Hits	110	Shared Neighborhood Hits	5
SwissProt Accessions	P41969	Gene names	Elk1
Domain Architecture
Description	ETS domain-containing protein Elk-1.

AKA11_HUMAN
NC score	0.017289 (rank : 61)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	67	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKA4, O75124, Q9NUK7	Gene names	AKAP11, AKAP220, KIAA0629
Domain Architecture
Description	A-kinase anchor protein 11 (Protein kinase A-anchoring protein 11) (PRKA11) (A kinase anchor protein 220 kDa) (AKAP 220) (hAKAP220).

K1688_HUMAN
NC score	0.015714 (rank : 62)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	67	Target Neighborhood Hits	217	Shared Neighborhood Hits	9
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

CCD45_MOUSE
NC score	0.015694 (rank : 63)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	67	Target Neighborhood Hits	663	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BVV7	Gene names	Ccdc45
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 45.

MILK1_MOUSE
NC score	0.013949 (rank : 64)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	67	Target Neighborhood Hits	788	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BGT6, Q8BJ60	Gene names	Mirab13, D15Mit260, Kiaa1668
Domain Architecture
Description	Molecule interacting with Rab13 (MIRab13) (MICAL-like protein 1).

OCRL_HUMAN
NC score	0.011702 (rank : 65)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	67	Target Neighborhood Hits	77	Shared Neighborhood Hits	3
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

REM1_HUMAN
NC score	0.010194 (rank : 66)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	67	Target Neighborhood Hits	247	Shared Neighborhood Hits	3
SwissProt Accessions	O75628, Q9NP57	Gene names	REM1, GES, REM
Domain Architecture
Description	GTP-binding protein REM 1 (Rad and Gem-like GTP-binding protein 1) (GTPase-regulating endothelial cell sprouting).

MY18B_HUMAN
NC score	0.010106 (rank : 67)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	67	Target Neighborhood Hits	1299	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

ANRA2_MOUSE
NC score	0.009857 (rank : 68)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	67	Target Neighborhood Hits	287	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PE2	Gene names	Ankra2, Ankra
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

NUMA1_HUMAN
NC score	0.009300 (rank : 69)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	67	Target Neighborhood Hits	1523	Shared Neighborhood Hits	18
SwissProt Accessions	Q14980, Q14981	Gene names	NUMA1, NUMA
Domain Architecture	No domain graphic available
Description	Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen).

IQGA2_HUMAN
NC score	0.009188 (rank : 70)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	67	Target Neighborhood Hits	200	Shared Neighborhood Hits	4
SwissProt Accessions	Q13576	Gene names	IQGAP2
Domain Architecture
Description	Ras GTPase-activating-like protein IQGAP2.

ANRA2_HUMAN
NC score	0.009040 (rank : 71)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	67	Target Neighborhood Hits	288	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H9E1	Gene names	ANKRA2, ANKRA
Domain Architecture
Description	Ankyrin repeat family A protein 2 (RFXANK-like 2).

PLEC1_HUMAN
NC score	0.008759 (rank : 72)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	67	Target Neighborhood Hits	1326	Shared Neighborhood Hits	15
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

KI21A_MOUSE
NC score	0.006517 (rank : 73)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	67	Target Neighborhood Hits	1317	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

MARK2_MOUSE
NC score	0.005144 (rank : 74)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	67	Target Neighborhood Hits	1018	Shared Neighborhood Hits	10
SwissProt Accessions	Q05512, Q6PDR4, Q8BR95	Gene names	Mark2, Emk
Domain Architecture
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL Motif Kinase) (EMK1).

CADH3_HUMAN
NC score	0.002868 (rank : 75)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	67	Target Neighborhood Hits	159	Shared Neighborhood Hits	2
SwissProt Accessions	P22223	Gene names	CDH3, CDHP
Domain Architecture
Description	Cadherin-3 precursor (Placental-cadherin) (P-cadherin).

MRCKB_MOUSE
NC score	0.001515 (rank : 76)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	67	Target Neighborhood Hits	2180	Shared Neighborhood Hits	12
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).