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Network neighborhood for query Sequence : NARG1_HUMAN

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NARG1_HUMAN
SwissProt Accessions	Q9BXJ9, Q8IWH4, Q8NEV2, Q9H8P6	Gene names	NARG1, GA19, NATH, TBDN100
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase) (Tubedown-1 protein) (Tbdn100) (Gastric cancer antigen Ga19).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NARG1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	114
SwissProt Accessions	Q9BXJ9, Q8IWH4, Q8NEV2, Q9H8P6	Gene names	NARG1, GA19, NATH, TBDN100
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase) (Tubedown-1 protein) (Tbdn100) (Gastric cancer antigen Ga19).

NARG1_MOUSE
θ value	0 (rank : 2)	NC score	0.998997 (rank : 2)
Query Neighborhood Hits	114	Target Neighborhood Hits	111	Shared Neighborhood Hits	107
SwissProt Accessions	Q80UM3, Q811Z9, Q9JID5	Gene names	Narg1, Nat1, Tbdn-1, Tubedown
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase 1) (Protein Tubedown-1).

NARGL_HUMAN
θ value	0 (rank : 3)	NC score	0.959732 (rank : 4)
Query Neighborhood Hits	114	Target Neighborhood Hits	222	Shared Neighborhood Hits	60
SwissProt Accessions	Q6N069, Q5VSP9, Q6P2D5, Q8N5J3, Q8N870	Gene names	NARG1L, NAT2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

NARGL_MOUSE
θ value	0 (rank : 4)	NC score	0.969679 (rank : 3)
Query Neighborhood Hits	114	Target Neighborhood Hits	175	Shared Neighborhood Hits	58
SwissProt Accessions	Q9DBB4, Q3U7V2	Gene names	Narg1l, Nat2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

IFT88_HUMAN
θ value	0.0113563 (rank : 5)	NC score	0.162828 (rank : 8)
Query Neighborhood Hits	114	Target Neighborhood Hits	122	Shared Neighborhood Hits	27
SwissProt Accessions	Q13099	Gene names	IFT88, TG737, TTC10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737 homolog).

IFT88_MOUSE
θ value	0.0193708 (rank : 6)	NC score	0.171551 (rank : 5)
Query Neighborhood Hits	114	Target Neighborhood Hits	124	Shared Neighborhood Hits	27
SwissProt Accessions	Q61371	Gene names	Ift88, Tg737, Tg737Rpw, TgN737Rpw, Ttc10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737) (TgN(Imorpk)737Rpw).

CRNL1_MOUSE
θ value	0.0252991 (rank : 7)	NC score	0.127841 (rank : 11)
Query Neighborhood Hits	114	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	P63154, Q542E8, Q9CQC1	Gene names	Crnkl1
Domain Architecture	No domain graphic available
Description	Crooked neck-like protein 1 (Crooked neck homolog).

TF3C3_HUMAN
θ value	0.0431538 (rank : 8)	NC score	0.158588 (rank : 9)
Query Neighborhood Hits	114	Target Neighborhood Hits	90	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5Q9, Q86XJ8, Q8WX84, Q96B44, Q9H5I8, Q9NT97	Gene names	GTF3C3
Domain Architecture
Description	General transcription factor 3C polypeptide 3 (Transcription factor IIIC-subunit gamma) (TF3C-gamma) (TFIIIC 102 kDa subunit) (TFIIIC102).

ANR18_HUMAN
θ value	0.0563607 (rank : 9)	NC score	0.043014 (rank : 67)
Query Neighborhood Hits	114	Target Neighborhood Hits	1106	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

BBS4_MOUSE
θ value	0.0563607 (rank : 10)	NC score	0.165661 (rank : 7)
Query Neighborhood Hits	114	Target Neighborhood Hits	95	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C1Z7, Q3UYF0, Q8CA57	Gene names	Bbs4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein homolog.

SM1L2_HUMAN
θ value	0.0563607 (rank : 11)	NC score	0.079123 (rank : 23)
Query Neighborhood Hits	114	Target Neighborhood Hits	1019	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

BBS4_HUMAN
θ value	0.0736092 (rank : 12)	NC score	0.166736 (rank : 6)
Query Neighborhood Hits	114	Target Neighborhood Hits	109	Shared Neighborhood Hits	26
SwissProt Accessions	Q96RK4, Q8NHU9, Q96H45	Gene names	BBS4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein.

LEO1_MOUSE
θ value	0.0736092 (rank : 13)	NC score	0.040465 (rank : 73)
Query Neighborhood Hits	114	Target Neighborhood Hits	946	Shared Neighborhood Hits	25
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

CRNL1_HUMAN
θ value	0.0961366 (rank : 14)	NC score	0.122229 (rank : 12)
Query Neighborhood Hits	114	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BZJ0, Q5JY64, Q8WYI5, Q9BZI9, Q9BZJ1, Q9BZJ2, Q9GZW7, Q9H8F8, Q9NQH5, Q9NYD8	Gene names	CRNKL1, CRN
Domain Architecture
Description	Crooked neck-like protein 1 (Crooked neck homolog) (hCrn).

ITSN1_HUMAN
θ value	0.125558 (rank : 15)	NC score	0.062279 (rank : 34)
Query Neighborhood Hits	114	Target Neighborhood Hits	1757	Shared Neighborhood Hits	61
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

SMC1A_HUMAN
θ value	0.125558 (rank : 16)	NC score	0.078189 (rank : 24)
Query Neighborhood Hits	114	Target Neighborhood Hits	1346	Shared Neighborhood Hits	63
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
θ value	0.125558 (rank : 17)	NC score	0.076857 (rank : 25)
Query Neighborhood Hits	114	Target Neighborhood Hits	1384	Shared Neighborhood Hits	63
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

TTC7B_HUMAN
θ value	0.125558 (rank : 18)	NC score	0.099673 (rank : 13)
Query Neighborhood Hits	114	Target Neighborhood Hits	58	Shared Neighborhood Hits	19
SwissProt Accessions	Q86TV6, Q86U24, Q86VT3	Gene names	TTC7B, TTC7L1
Domain Architecture
Description	Tetratricopeptide repeat protein 7B (Tetratricopeptide repeat protein 7-like-1).

MYH11_MOUSE
θ value	0.21417 (rank : 19)	NC score	0.044517 (rank : 64)
Query Neighborhood Hits	114	Target Neighborhood Hits	1777	Shared Neighborhood Hits	61
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

STIP1_HUMAN
θ value	0.21417 (rank : 20)	NC score	0.099254 (rank : 14)
Query Neighborhood Hits	114	Target Neighborhood Hits	147	Shared Neighborhood Hits	29
SwissProt Accessions	P31948	Gene names	STIP1
Domain Architecture
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Transformation-sensitive protein IEF SSP 3521) (NY- REN-11 antigen).

ITSN1_MOUSE
θ value	0.279714 (rank : 21)	NC score	0.063075 (rank : 33)
Query Neighborhood Hits	114	Target Neighborhood Hits	1669	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ROCK1_MOUSE
θ value	0.279714 (rank : 22)	NC score	0.031348 (rank : 88)
Query Neighborhood Hits	114	Target Neighborhood Hits	2126	Shared Neighborhood Hits	64
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

DNJC3_MOUSE
θ value	0.365318 (rank : 23)	NC score	0.058710 (rank : 37)
Query Neighborhood Hits	114	Target Neighborhood Hits	230	Shared Neighborhood Hits	25
SwissProt Accessions	Q91YW3, Q60873	Gene names	Dnajc3, P58ipk
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

DTD1_HUMAN
θ value	0.365318 (rank : 24)	NC score	0.083649 (rank : 17)
Query Neighborhood Hits	114	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TEA8, Q496D1, Q5W184, Q8WXU8, Q9BW67, Q9H464, Q9H474	Gene names	HARS2, C20orf88
Domain Architecture
Description	Probable D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-).

STK6_HUMAN
θ value	0.365318 (rank : 25)	NC score	0.009199 (rank : 118)
Query Neighborhood Hits	114	Target Neighborhood Hits	916	Shared Neighborhood Hits	9
SwissProt Accessions	O14965, O60445, O75873, Q9BQD6, Q9UPG5	Gene names	STK6, AIK, ARK1, AURA, BTAK, STK15
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase).

ITSN2_MOUSE
θ value	0.47712 (rank : 26)	NC score	0.058247 (rank : 38)
Query Neighborhood Hits	114	Target Neighborhood Hits	1371	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

STK6_MOUSE
θ value	0.47712 (rank : 27)	NC score	0.008864 (rank : 119)
Query Neighborhood Hits	114	Target Neighborhood Hits	886	Shared Neighborhood Hits	8
SwissProt Accessions	P97477, O35624, Q91YU4	Gene names	Stk6, Ark1, Aurka, Ayk1, Iak1
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1).

CP26A_MOUSE
θ value	0.62314 (rank : 28)	NC score	0.024626 (rank : 96)
Query Neighborhood Hits	114	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	O55127, Q9R1F4	Gene names	Cyp26a1, Cyp26, P450ra
Domain Architecture
Description	Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic acid-metabolizing cytochrome) (P450RAI) (Retinoic acid 4-hydroxylase).

K1279_MOUSE
θ value	0.62314 (rank : 29)	NC score	0.050116 (rank : 49)
Query Neighborhood Hits	114	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZPU9, Q5BKR5, Q7TPE0, Q80VQ5, Q8BZE2, Q8CFS7	Gene names	Kiaa1279
Domain Architecture	No domain graphic available
Description	Protein KIAA1279.

MKL1_MOUSE
θ value	0.62314 (rank : 30)	NC score	0.030885 (rank : 89)
Query Neighborhood Hits	114	Target Neighborhood Hits	667	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

OGT1_HUMAN
θ value	0.62314 (rank : 31)	NC score	0.090732 (rank : 15)
Query Neighborhood Hits	114	Target Neighborhood Hits	143	Shared Neighborhood Hits	27
SwissProt Accessions	O15294, Q7Z3K0, Q8WWM8, Q96CC1, Q9UG57	Gene names	OGT
Domain Architecture
Description	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.-) (O-GlcNAc transferase p110 subunit).

MY18A_MOUSE
θ value	0.813845 (rank : 32)	NC score	0.045378 (rank : 61)
Query Neighborhood Hits	114	Target Neighborhood Hits	1989	Shared Neighborhood Hits	62
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TTC8_HUMAN
θ value	0.813845 (rank : 33)	NC score	0.082266 (rank : 19)
Query Neighborhood Hits	114	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TAM2, Q86SY0, Q86TV9, Q86U26, Q8NDH9, Q96DG8	Gene names	TTC8, BBS8
Domain Architecture
Description	Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet- Biedl syndrome 8 protein).

DNJC3_HUMAN
θ value	1.06291 (rank : 34)	NC score	0.056701 (rank : 40)
Query Neighborhood Hits	114	Target Neighborhood Hits	223	Shared Neighborhood Hits	25
SwissProt Accessions	Q13217, Q86WT9, Q8N4N2	Gene names	DNAJC3, P58IPK, PRKRI
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

DTD1_MOUSE
θ value	1.06291 (rank : 35)	NC score	0.072385 (rank : 28)
Query Neighborhood Hits	114	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DD18, Q9CRE8, Q9CYL0, Q9D013, Q9D1G4	Gene names	Hars2
Domain Architecture
Description	Probable D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-).

DYXC1_HUMAN
θ value	1.06291 (rank : 36)	NC score	0.081622 (rank : 20)
Query Neighborhood Hits	114	Target Neighborhood Hits	261	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

IFIT1_HUMAN
θ value	1.06291 (rank : 37)	NC score	0.074458 (rank : 27)
Query Neighborhood Hits	114	Target Neighborhood Hits	56	Shared Neighborhood Hits	16
SwissProt Accessions	P09914, Q96QM5	Gene names	IFIT1, G10P1, IFI56
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K).

ITSN2_HUMAN
θ value	1.06291 (rank : 38)	NC score	0.046546 (rank : 56)
Query Neighborhood Hits	114	Target Neighborhood Hits	1173	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

KLC1_HUMAN
θ value	1.06291 (rank : 39)	NC score	0.037592 (rank : 81)
Query Neighborhood Hits	114	Target Neighborhood Hits	471	Shared Neighborhood Hits	45
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

RAI14_MOUSE
θ value	1.06291 (rank : 40)	NC score	0.033806 (rank : 83)
Query Neighborhood Hits	114	Target Neighborhood Hits	1505	Shared Neighborhood Hits	53
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

SAS6_MOUSE
θ value	1.06291 (rank : 41)	NC score	0.050104 (rank : 50)
Query Neighborhood Hits	114	Target Neighborhood Hits	931	Shared Neighborhood Hits	54
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

STIP1_MOUSE
θ value	1.06291 (rank : 42)	NC score	0.090269 (rank : 16)
Query Neighborhood Hits	114	Target Neighborhood Hits	154	Shared Neighborhood Hits	26
SwissProt Accessions	Q60864, Q3TT16, Q8BPH3, Q99L66	Gene names	Stip1
Domain Architecture	No domain graphic available
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (mSTI1).

CP26A_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.021838 (rank : 109)
Query Neighborhood Hits	114	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	O43174	Gene names	CYP26A1, CYP26, P450RAI1
Domain Architecture
Description	Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic acid-metabolizing cytochrome) (P450 retinoic acid-inactivating 1) (P450RAI) (hP450RAI) (Retinoic acid 4-hydroxylase).

EEA1_MOUSE
θ value	1.38821 (rank : 44)	NC score	0.053978 (rank : 46)
Query Neighborhood Hits	114	Target Neighborhood Hits	1637	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

P52K_HUMAN
θ value	1.38821 (rank : 45)	NC score	0.070861 (rank : 31)
Query Neighborhood Hits	114	Target Neighborhood Hits	142	Shared Neighborhood Hits	13
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

SMC2_HUMAN
θ value	1.38821 (rank : 46)	NC score	0.059835 (rank : 36)
Query Neighborhood Hits	114	Target Neighborhood Hits	1405	Shared Neighborhood Hits	59
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

UTY_MOUSE
θ value	1.38821 (rank : 47)	NC score	0.079380 (rank : 22)
Query Neighborhood Hits	114	Target Neighborhood Hits	64	Shared Neighborhood Hits	19
SwissProt Accessions	P79457, O97979	Gene names	Uty
Domain Architecture
Description	Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein ON the Y chromosome) (Male- specific histocompatibility antigen H-YDB).

CROCC_HUMAN
θ value	1.81305 (rank : 48)	NC score	0.045611 (rank : 60)
Query Neighborhood Hits	114	Target Neighborhood Hits	1409	Shared Neighborhood Hits	55
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

GOGA4_MOUSE
θ value	1.81305 (rank : 49)	NC score	0.042164 (rank : 69)
Query Neighborhood Hits	114	Target Neighborhood Hits	1939	Shared Neighborhood Hits	60
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

LIPA1_HUMAN
θ value	1.81305 (rank : 50)	NC score	0.043910 (rank : 66)
Query Neighborhood Hits	114	Target Neighborhood Hits	1294	Shared Neighborhood Hits	62
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

MYH11_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.041581 (rank : 70)
Query Neighborhood Hits	114	Target Neighborhood Hits	1806	Shared Neighborhood Hits	62
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH9_MOUSE
θ value	1.81305 (rank : 52)	NC score	0.039763 (rank : 76)
Query Neighborhood Hits	114	Target Neighborhood Hits	1829	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

ROCK2_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.023675 (rank : 102)
Query Neighborhood Hits	114	Target Neighborhood Hits	2073	Shared Neighborhood Hits	61
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

A4_MOUSE
θ value	2.36792 (rank : 54)	NC score	0.036934 (rank : 82)
Query Neighborhood Hits	114	Target Neighborhood Hits	275	Shared Neighborhood Hits	24
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

EEA1_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.047851 (rank : 53)
Query Neighborhood Hits	114	Target Neighborhood Hits	1796	Shared Neighborhood Hits	60
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

GOGB1_HUMAN
θ value	2.36792 (rank : 56)	NC score	0.045618 (rank : 59)
Query Neighborhood Hits	114	Target Neighborhood Hits	2297	Shared Neighborhood Hits	67
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

RBCC1_HUMAN
θ value	2.36792 (rank : 57)	NC score	0.042179 (rank : 68)
Query Neighborhood Hits	114	Target Neighborhood Hits	1023	Shared Neighborhood Hits	53
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

SDCG8_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.049858 (rank : 51)
Query Neighborhood Hits	114	Target Neighborhood Hits	1002	Shared Neighborhood Hits	55
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

SDCG8_MOUSE
θ value	2.36792 (rank : 59)	NC score	0.051741 (rank : 48)
Query Neighborhood Hits	114	Target Neighborhood Hits	886	Shared Neighborhood Hits	56
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

STK10_MOUSE
θ value	2.36792 (rank : 60)	NC score	0.021620 (rank : 110)
Query Neighborhood Hits	114	Target Neighborhood Hits	2132	Shared Neighborhood Hits	60
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

TPM1_MOUSE
θ value	2.36792 (rank : 61)	NC score	0.046832 (rank : 54)
Query Neighborhood Hits	114	Target Neighborhood Hits	729	Shared Neighborhood Hits	55
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

KIF23_HUMAN
θ value	3.0926 (rank : 62)	NC score	0.030760 (rank : 90)
Query Neighborhood Hits	114	Target Neighborhood Hits	618	Shared Neighborhood Hits	48
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

SYCP1_HUMAN
θ value	3.0926 (rank : 63)	NC score	0.046632 (rank : 55)
Query Neighborhood Hits	114	Target Neighborhood Hits	1313	Shared Neighborhood Hits	59
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TPM1_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.045841 (rank : 58)
Query Neighborhood Hits	114	Target Neighborhood Hits	716	Shared Neighborhood Hits	54
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

WDR19_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.030048 (rank : 91)
Query Neighborhood Hits	114	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NEZ3, Q8N5B4, Q9H5S0, Q9HCD4	Gene names	WDR19, KIAA1638
Domain Architecture	No domain graphic available
Description	WD repeat protein 19.

A4_HUMAN
θ value	4.03905 (rank : 66)	NC score	0.038807 (rank : 77)
Query Neighborhood Hits	114	Target Neighborhood Hits	274	Shared Neighborhood Hits	27
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

ANR12_HUMAN
θ value	4.03905 (rank : 67)	NC score	0.029258 (rank : 92)
Query Neighborhood Hits	114	Target Neighborhood Hits	1081	Shared Neighborhood Hits	56
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

GGT1_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.016634 (rank : 115)
Query Neighborhood Hits	114	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q60928	Gene names	Ggt1, Ggt, Ggtp
Domain Architecture
Description	Gamma-glutamyltranspeptidase 1 precursor (EC 2.3.2.2) (Gamma- glutamyltransferase 1) (GGT 1) (CD224 antigen) [Contains: Gamma- glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain].

KIF11_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.023821 (rank : 100)
Query Neighborhood Hits	114	Target Neighborhood Hits	583	Shared Neighborhood Hits	45
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

MTSS1_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.027279 (rank : 95)
Query Neighborhood Hits	114	Target Neighborhood Hits	504	Shared Neighborhood Hits	22
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

MY18A_HUMAN
θ value	4.03905 (rank : 71)	NC score	0.044529 (rank : 63)
Query Neighborhood Hits	114	Target Neighborhood Hits	1929	Shared Neighborhood Hits	62
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

RAD50_MOUSE
θ value	4.03905 (rank : 72)	NC score	0.046322 (rank : 57)
Query Neighborhood Hits	114	Target Neighborhood Hits	1366	Shared Neighborhood Hits	55
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RF1M_MOUSE
θ value	4.03905 (rank : 73)	NC score	0.028622 (rank : 93)
Query Neighborhood Hits	114	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K126	Gene names	Mtrf1
Domain Architecture
Description	Peptide chain release factor 1, mitochondrial precursor (MRF-1).

TTC13_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.082689 (rank : 18)
Query Neighborhood Hits	114	Target Neighborhood Hits	117	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NBP0, Q8IVP8, Q8NBI0, Q8ND20	Gene names	TTC13
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 13 (TPR repeat protein 13).

TTC7A_HUMAN
θ value	4.03905 (rank : 75)	NC score	0.076720 (rank : 26)
Query Neighborhood Hits	114	Target Neighborhood Hits	79	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ULT0, Q6PIX4, Q8ND67, Q9BUS3	Gene names	TTC7A, KIAA1140, TTC7
Domain Architecture
Description	Tetratricopeptide repeat protein 7A (TPR repeat protein 7).

TTC8_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.065254 (rank : 32)
Query Neighborhood Hits	114	Target Neighborhood Hits	55	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VD72, Q9DCP7	Gene names	Ttc8, Bbs8
Domain Architecture
Description	Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet- Biedl syndrome 8 protein homolog).

AURKB_MOUSE
θ value	5.27518 (rank : 77)	NC score	0.005534 (rank : 120)
Query Neighborhood Hits	114	Target Neighborhood Hits	858	Shared Neighborhood Hits	8
SwissProt Accessions	O70126, Q61882	Gene names	Aurkb, Ark2, Stk1, Stk12, Stk5
Domain Architecture
Description	Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-B) (Aurora- related kinase 2) (Serine/threonine-protein kinase 5) (STK-1).

CDC23_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.071263 (rank : 29)
Query Neighborhood Hits	114	Target Neighborhood Hits	69	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UJX2, O75433, Q9BS73	Gene names	CDC23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

FRG1_MOUSE
θ value	5.27518 (rank : 79)	NC score	0.028155 (rank : 94)
Query Neighborhood Hits	114	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P97376, Q99M42	Gene names	Frg1
Domain Architecture
Description	Protein FRG1 (FSHD region gene 1 protein).

RB6I2_HUMAN
θ value	5.27518 (rank : 80)	NC score	0.044013 (rank : 65)
Query Neighborhood Hits	114	Target Neighborhood Hits	1584	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

SYCP2_HUMAN
θ value	5.27518 (rank : 81)	NC score	0.062021 (rank : 35)
Query Neighborhood Hits	114	Target Neighborhood Hits	230	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

TEKT1_HUMAN
θ value	5.27518 (rank : 82)	NC score	0.038009 (rank : 79)
Query Neighborhood Hits	114	Target Neighborhood Hits	289	Shared Neighborhood Hits	38
SwissProt Accessions	Q969V4	Gene names	TEKT1
Domain Architecture
Description	Tektin-1.

VPS53_HUMAN
θ value	5.27518 (rank : 83)	NC score	0.024571 (rank : 97)
Query Neighborhood Hits	114	Target Neighborhood Hits	107	Shared Neighborhood Hits	15
SwissProt Accessions	Q5VIR6, Q8WYW3, Q9BRR2, Q9BY02, Q9NV25	Gene names	VPS53
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 53.

VPS53_MOUSE
θ value	5.27518 (rank : 84)	NC score	0.023880 (rank : 99)
Query Neighborhood Hits	114	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CCB4, Q8C7U0, Q8CIA1, Q9CX82, Q9D6T7	Gene names	Vps53
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 53.

WDR19_MOUSE
θ value	5.27518 (rank : 85)	NC score	0.021302 (rank : 113)
Query Neighborhood Hits	114	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UGF1, Q6ZPK8, Q80VQ6, Q8C794, Q8K3R5	Gene names	Wdr19, Kiaa1638
Domain Architecture	No domain graphic available
Description	WD repeat protein 19.

ANR21_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.022017 (rank : 108)
Query Neighborhood Hits	114	Target Neighborhood Hits	864	Shared Neighborhood Hits	46
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

BPIL1_MOUSE
θ value	6.88961 (rank : 87)	NC score	0.022714 (rank : 105)
Query Neighborhood Hits	114	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C1E1, Q3TUY4, Q8BVZ0, Q8C1E2, Q9D713, Q9D744	Gene names	Bpil1
Domain Architecture
Description	Bactericidal/permeability-increasing protein-like 1 precursor.

IFIT2_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.023715 (rank : 101)
Query Neighborhood Hits	114	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	P09913	Gene names	IFIT2, G10P2, IFI54
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2) (Interferon-induced 54 kDa protein) (IFI-54K) (ISG-54 K).

K0372_HUMAN
θ value	6.88961 (rank : 89)	NC score	0.139350 (rank : 10)
Query Neighborhood Hits	114	Target Neighborhood Hits	136	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PGP7, O15077, Q6PJI3	Gene names	KIAA0372
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein KIAA0372 (TPR repeat protein KIAA0372).

KI21A_MOUSE
θ value	6.88961 (rank : 90)	NC score	0.033017 (rank : 85)
Query Neighborhood Hits	114	Target Neighborhood Hits	1317	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

KI67_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.018661 (rank : 114)
Query Neighborhood Hits	114	Target Neighborhood Hits	581	Shared Neighborhood Hits	16
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

LSD1_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.021327 (rank : 112)
Query Neighborhood Hits	114	Target Neighborhood Hits	455	Shared Neighborhood Hits	26
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

LSD1_MOUSE
θ value	6.88961 (rank : 93)	NC score	0.022888 (rank : 104)
Query Neighborhood Hits	114	Target Neighborhood Hits	224	Shared Neighborhood Hits	26
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

MYH10_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.038225 (rank : 78)
Query Neighborhood Hits	114	Target Neighborhood Hits	1612	Shared Neighborhood Hits	66
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH6_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.040579 (rank : 72)
Query Neighborhood Hits	114	Target Neighborhood Hits	1426	Shared Neighborhood Hits	61
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH6_MOUSE
θ value	6.88961 (rank : 96)	NC score	0.041526 (rank : 71)
Query Neighborhood Hits	114	Target Neighborhood Hits	1501	Shared Neighborhood Hits	66
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH7_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.039952 (rank : 75)
Query Neighborhood Hits	114	Target Neighborhood Hits	1559	Shared Neighborhood Hits	63
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

TTC7A_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.071042 (rank : 30)
Query Neighborhood Hits	114	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BGB2, Q80XT5	Gene names	Ttc7a, Ttc7
Domain Architecture
Description	Tetratricopeptide repeat protein 7A (TPR repeat protein 7).

UTY_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.048790 (rank : 52)
Query Neighborhood Hits	114	Target Neighborhood Hits	89	Shared Neighborhood Hits	20
SwissProt Accessions	O14607, O14608	Gene names	UTY
Domain Architecture
Description	Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the Y chromosome).

ZN318_MOUSE
θ value	6.88961 (rank : 100)	NC score	0.031746 (rank : 87)
Query Neighborhood Hits	114	Target Neighborhood Hits	642	Shared Neighborhood Hits	38
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

AN32E_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.023938 (rank : 98)
Query Neighborhood Hits	114	Target Neighborhood Hits	291	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

AN32E_MOUSE
θ value	8.99809 (rank : 102)	NC score	0.022904 (rank : 103)
Query Neighborhood Hits	114	Target Neighborhood Hits	257	Shared Neighborhood Hits	12
SwissProt Accessions	P97822, Q3TH89, Q8BPF8, Q8C2L4, Q8C7Q8, Q9CZD2	Gene names	Anp32e, Cpd1
Domain Architecture
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L) (Cerebellar postnatal development protein 1).

CASP_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.037626 (rank : 80)
Query Neighborhood Hits	114	Target Neighborhood Hits	1131	Shared Neighborhood Hits	57
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

CUTL1_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.033437 (rank : 84)
Query Neighborhood Hits	114	Target Neighborhood Hits	1574	Shared Neighborhood Hits	57
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

FANCG_MOUSE
θ value	8.99809 (rank : 105)	NC score	0.011324 (rank : 116)
Query Neighborhood Hits	114	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQR6	Gene names	Fancg
Domain Architecture	No domain graphic available
Description	Fanconi anemia group G protein homolog (Protein FACG).

FRG1_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.022574 (rank : 106)
Query Neighborhood Hits	114	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q14331	Gene names	FRG1
Domain Architecture
Description	Protein FRG1 (FSHD region gene 1 protein).

GOGA4_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.044824 (rank : 62)
Query Neighborhood Hits	114	Target Neighborhood Hits	2034	Shared Neighborhood Hits	68
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

KI21A_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.032769 (rank : 86)
Query Neighborhood Hits	114	Target Neighborhood Hits	1543	Shared Neighborhood Hits	58
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

KNTC2_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.040092 (rank : 74)
Query Neighborhood Hits	114	Target Neighborhood Hits	673	Shared Neighborhood Hits	52
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

LEO1_HUMAN
θ value	8.99809 (rank : 110)	NC score	0.022120 (rank : 107)
Query Neighborhood Hits	114	Target Neighborhood Hits	958	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

LY10_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.010671 (rank : 117)
Query Neighborhood Hits	114	Target Neighborhood Hits	151	Shared Neighborhood Hits	4
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

POT15_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.021348 (rank : 111)
Query Neighborhood Hits	114	Target Neighborhood Hits	893	Shared Neighborhood Hits	47
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

UBE3A_MOUSE
θ value	8.99809 (rank : 113)	NC score	0.004213 (rank : 121)
Query Neighborhood Hits	114	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

UTX_HUMAN
θ value	8.99809 (rank : 114)	NC score	0.052905 (rank : 47)
Query Neighborhood Hits	114	Target Neighborhood Hits	161	Shared Neighborhood Hits	20
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

CDC23_MOUSE
θ value	θ > 10 (rank : 115)	NC score	0.054682 (rank : 43)
Query Neighborhood Hits	114	Target Neighborhood Hits	65	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BGZ4, Q8C0F1	Gene names	Cdc23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

CDC27_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.080490 (rank : 21)
Query Neighborhood Hits	114	Target Neighborhood Hits	139	Shared Neighborhood Hits	24
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

CTR9_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.055357 (rank : 42)
Query Neighborhood Hits	114	Target Neighborhood Hits	383	Shared Neighborhood Hits	52
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

CTR9_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.054495 (rank : 44)
Query Neighborhood Hits	114	Target Neighborhood Hits	427	Shared Neighborhood Hits	51
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

GEMI_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.055920 (rank : 41)
Query Neighborhood Hits	114	Target Neighborhood Hits	163	Shared Neighborhood Hits	21
SwissProt Accessions	O88513	Gene names	Gmnn
Domain Architecture
Description	Geminin.

SM1L2_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.057225 (rank : 39)
Query Neighborhood Hits	114	Target Neighborhood Hits	918	Shared Neighborhood Hits	49
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

TTC6_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.054116 (rank : 45)
Query Neighborhood Hits	114	Target Neighborhood Hits	103	Shared Neighborhood Hits	23
SwissProt Accessions	Q86TZ1, Q96CE6	Gene names	TTC6
Domain Architecture
Description	Tetratricopeptide repeat protein 6 (TPR repeat protein 6).

Hits sorted by NC score

NARG1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	114
SwissProt Accessions	Q9BXJ9, Q8IWH4, Q8NEV2, Q9H8P6	Gene names	NARG1, GA19, NATH, TBDN100
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase) (Tubedown-1 protein) (Tbdn100) (Gastric cancer antigen Ga19).

NARG1_MOUSE
NC score	0.998997 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	114	Target Neighborhood Hits	111	Shared Neighborhood Hits	107
SwissProt Accessions	Q80UM3, Q811Z9, Q9JID5	Gene names	Narg1, Nat1, Tbdn-1, Tubedown
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated protein 1 (N-terminal acetyltransferase 1) (Protein Tubedown-1).

NARGL_MOUSE
NC score	0.969679 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	114	Target Neighborhood Hits	175	Shared Neighborhood Hits	58
SwissProt Accessions	Q9DBB4, Q3U7V2	Gene names	Narg1l, Nat2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

NARGL_HUMAN
NC score	0.959732 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	114	Target Neighborhood Hits	222	Shared Neighborhood Hits	60
SwissProt Accessions	Q6N069, Q5VSP9, Q6P2D5, Q8N5J3, Q8N870	Gene names	NARG1L, NAT2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

IFT88_MOUSE
NC score	0.171551 (rank : 5)	θ value	0.0193708 (rank : 6)
Query Neighborhood Hits	114	Target Neighborhood Hits	124	Shared Neighborhood Hits	27
SwissProt Accessions	Q61371	Gene names	Ift88, Tg737, Tg737Rpw, TgN737Rpw, Ttc10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737) (TgN(Imorpk)737Rpw).

BBS4_HUMAN
NC score	0.166736 (rank : 6)	θ value	0.0736092 (rank : 12)
Query Neighborhood Hits	114	Target Neighborhood Hits	109	Shared Neighborhood Hits	26
SwissProt Accessions	Q96RK4, Q8NHU9, Q96H45	Gene names	BBS4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein.

BBS4_MOUSE
NC score	0.165661 (rank : 7)	θ value	0.0563607 (rank : 10)
Query Neighborhood Hits	114	Target Neighborhood Hits	95	Shared Neighborhood Hits	27
SwissProt Accessions	Q8C1Z7, Q3UYF0, Q8CA57	Gene names	Bbs4
Domain Architecture
Description	Bardet-Biedl syndrome 4 protein homolog.

IFT88_HUMAN
NC score	0.162828 (rank : 8)	θ value	0.0113563 (rank : 5)
Query Neighborhood Hits	114	Target Neighborhood Hits	122	Shared Neighborhood Hits	27
SwissProt Accessions	Q13099	Gene names	IFT88, TG737, TTC10
Domain Architecture
Description	Intraflagellar transport 88 homolog (Tetratricopeptide repeat protein 10) (TPR repeat protein 10) (Recessive polycystic kidney disease protein Tg737 homolog).

TF3C3_HUMAN
NC score	0.158588 (rank : 9)	θ value	0.0431538 (rank : 8)
Query Neighborhood Hits	114	Target Neighborhood Hits	90	Shared Neighborhood Hits	27
SwissProt Accessions	Q9Y5Q9, Q86XJ8, Q8WX84, Q96B44, Q9H5I8, Q9NT97	Gene names	GTF3C3
Domain Architecture
Description	General transcription factor 3C polypeptide 3 (Transcription factor IIIC-subunit gamma) (TF3C-gamma) (TFIIIC 102 kDa subunit) (TFIIIC102).

K0372_HUMAN
NC score	0.139350 (rank : 10)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	114	Target Neighborhood Hits	136	Shared Neighborhood Hits	31
SwissProt Accessions	Q6PGP7, O15077, Q6PJI3	Gene names	KIAA0372
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein KIAA0372 (TPR repeat protein KIAA0372).

CRNL1_MOUSE
NC score	0.127841 (rank : 11)	θ value	0.0252991 (rank : 7)
Query Neighborhood Hits	114	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	P63154, Q542E8, Q9CQC1	Gene names	Crnkl1
Domain Architecture	No domain graphic available
Description	Crooked neck-like protein 1 (Crooked neck homolog).

CRNL1_HUMAN
NC score	0.122229 (rank : 12)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	114	Target Neighborhood Hits	76	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BZJ0, Q5JY64, Q8WYI5, Q9BZI9, Q9BZJ1, Q9BZJ2, Q9GZW7, Q9H8F8, Q9NQH5, Q9NYD8	Gene names	CRNKL1, CRN
Domain Architecture
Description	Crooked neck-like protein 1 (Crooked neck homolog) (hCrn).

TTC7B_HUMAN
NC score	0.099673 (rank : 13)	θ value	0.125558 (rank : 18)
Query Neighborhood Hits	114	Target Neighborhood Hits	58	Shared Neighborhood Hits	19
SwissProt Accessions	Q86TV6, Q86U24, Q86VT3	Gene names	TTC7B, TTC7L1
Domain Architecture
Description	Tetratricopeptide repeat protein 7B (Tetratricopeptide repeat protein 7-like-1).

STIP1_HUMAN
NC score	0.099254 (rank : 14)	θ value	0.21417 (rank : 20)
Query Neighborhood Hits	114	Target Neighborhood Hits	147	Shared Neighborhood Hits	29
SwissProt Accessions	P31948	Gene names	STIP1
Domain Architecture
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Transformation-sensitive protein IEF SSP 3521) (NY- REN-11 antigen).

OGT1_HUMAN
NC score	0.090732 (rank : 15)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	114	Target Neighborhood Hits	143	Shared Neighborhood Hits	27
SwissProt Accessions	O15294, Q7Z3K0, Q8WWM8, Q96CC1, Q9UG57	Gene names	OGT
Domain Architecture
Description	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.-) (O-GlcNAc transferase p110 subunit).

STIP1_MOUSE
NC score	0.090269 (rank : 16)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	114	Target Neighborhood Hits	154	Shared Neighborhood Hits	26
SwissProt Accessions	Q60864, Q3TT16, Q8BPH3, Q99L66	Gene names	Stip1
Domain Architecture	No domain graphic available
Description	Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (mSTI1).

DTD1_HUMAN
NC score	0.083649 (rank : 17)	θ value	0.365318 (rank : 24)
Query Neighborhood Hits	114	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TEA8, Q496D1, Q5W184, Q8WXU8, Q9BW67, Q9H464, Q9H474	Gene names	HARS2, C20orf88
Domain Architecture
Description	Probable D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-).

TTC13_HUMAN
NC score	0.082689 (rank : 18)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	114	Target Neighborhood Hits	117	Shared Neighborhood Hits	26
SwissProt Accessions	Q8NBP0, Q8IVP8, Q8NBI0, Q8ND20	Gene names	TTC13
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 13 (TPR repeat protein 13).

TTC8_HUMAN
NC score	0.082266 (rank : 19)	θ value	0.813845 (rank : 33)
Query Neighborhood Hits	114	Target Neighborhood Hits	56	Shared Neighborhood Hits	20
SwissProt Accessions	Q8TAM2, Q86SY0, Q86TV9, Q86U26, Q8NDH9, Q96DG8	Gene names	TTC8, BBS8
Domain Architecture
Description	Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet- Biedl syndrome 8 protein).

DYXC1_HUMAN
NC score	0.081622 (rank : 20)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	114	Target Neighborhood Hits	261	Shared Neighborhood Hits	37
SwissProt Accessions	Q8WXU2, Q6P5Y9	Gene names	DYX1C1, EKN1
Domain Architecture
Description	Dyslexia susceptibility 1 candidate gene 1 protein.

CDC27_HUMAN
NC score	0.080490 (rank : 21)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	114	Target Neighborhood Hits	139	Shared Neighborhood Hits	24
SwissProt Accessions	P30260, Q16349, Q96F35	Gene names	CDC27
Domain Architecture
Description	Cell division cycle protein 27 homolog (CDC27Hs) (H-NUC).

UTY_MOUSE
NC score	0.079380 (rank : 22)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	114	Target Neighborhood Hits	64	Shared Neighborhood Hits	19
SwissProt Accessions	P79457, O97979	Gene names	Uty
Domain Architecture
Description	Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein ON the Y chromosome) (Male- specific histocompatibility antigen H-YDB).

SM1L2_HUMAN
NC score	0.079123 (rank : 23)	θ value	0.0563607 (rank : 11)
Query Neighborhood Hits	114	Target Neighborhood Hits	1019	Shared Neighborhood Hits	52
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

SMC1A_HUMAN
NC score	0.078189 (rank : 24)	θ value	0.125558 (rank : 16)
Query Neighborhood Hits	114	Target Neighborhood Hits	1346	Shared Neighborhood Hits	63
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

SMC1A_MOUSE
NC score	0.076857 (rank : 25)	θ value	0.125558 (rank : 17)
Query Neighborhood Hits	114	Target Neighborhood Hits	1384	Shared Neighborhood Hits	63
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

TTC7A_HUMAN
NC score	0.076720 (rank : 26)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	114	Target Neighborhood Hits	79	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ULT0, Q6PIX4, Q8ND67, Q9BUS3	Gene names	TTC7A, KIAA1140, TTC7
Domain Architecture
Description	Tetratricopeptide repeat protein 7A (TPR repeat protein 7).

IFIT1_HUMAN
NC score	0.074458 (rank : 27)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	114	Target Neighborhood Hits	56	Shared Neighborhood Hits	16
SwissProt Accessions	P09914, Q96QM5	Gene names	IFIT1, G10P1, IFI56
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K).

DTD1_MOUSE
NC score	0.072385 (rank : 28)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	114	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DD18, Q9CRE8, Q9CYL0, Q9D013, Q9D1G4	Gene names	Hars2
Domain Architecture
Description	Probable D-tyrosyl-tRNA(Tyr) deacylase (EC 3.1.-.-).

CDC23_HUMAN
NC score	0.071263 (rank : 29)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	114	Target Neighborhood Hits	69	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UJX2, O75433, Q9BS73	Gene names	CDC23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

TTC7A_MOUSE
NC score	0.071042 (rank : 30)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	114	Target Neighborhood Hits	85	Shared Neighborhood Hits	28
SwissProt Accessions	Q8BGB2, Q80XT5	Gene names	Ttc7a, Ttc7
Domain Architecture
Description	Tetratricopeptide repeat protein 7A (TPR repeat protein 7).

P52K_HUMAN
NC score	0.070861 (rank : 31)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	114	Target Neighborhood Hits	142	Shared Neighborhood Hits	13
SwissProt Accessions	O43422, Q8WTW1, Q9Y3Z4	Gene names	PRKRIR, DAP4, P52RIPK, THAP0
Domain Architecture
Description	52 kDa repressor of the inhibitor of the protein kinase (p58IPK- interacting protein) (58 kDa interferon-induced protein kinase- interacting protein) (P52rIPK) (Death-associated protein 4) (THAP domain-containing protein 0).

TTC8_MOUSE
NC score	0.065254 (rank : 32)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	114	Target Neighborhood Hits	55	Shared Neighborhood Hits	18
SwissProt Accessions	Q8VD72, Q9DCP7	Gene names	Ttc8, Bbs8
Domain Architecture
Description	Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet- Biedl syndrome 8 protein homolog).

ITSN1_MOUSE
NC score	0.063075 (rank : 33)	θ value	0.279714 (rank : 21)
Query Neighborhood Hits	114	Target Neighborhood Hits	1669	Shared Neighborhood Hits	57
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN1_HUMAN
NC score	0.062279 (rank : 34)	θ value	0.125558 (rank : 15)
Query Neighborhood Hits	114	Target Neighborhood Hits	1757	Shared Neighborhood Hits	61
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

SYCP2_HUMAN
NC score	0.062021 (rank : 35)	θ value	5.27518 (rank : 81)
Query Neighborhood Hits	114	Target Neighborhood Hits	230	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BX26, O75763, Q5JX11, Q9NTX8, Q9UG27	Gene names	SYCP2, SCP2
Domain Architecture	No domain graphic available
Description	Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein) (hsSCP2).

SMC2_HUMAN
NC score	0.059835 (rank : 36)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	114	Target Neighborhood Hits	1405	Shared Neighborhood Hits	59
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

DNJC3_MOUSE
NC score	0.058710 (rank : 37)	θ value	0.365318 (rank : 23)
Query Neighborhood Hits	114	Target Neighborhood Hits	230	Shared Neighborhood Hits	25
SwissProt Accessions	Q91YW3, Q60873	Gene names	Dnajc3, P58ipk
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

ITSN2_MOUSE
NC score	0.058247 (rank : 38)	θ value	0.47712 (rank : 26)
Query Neighborhood Hits	114	Target Neighborhood Hits	1371	Shared Neighborhood Hits	58
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

SM1L2_MOUSE
NC score	0.057225 (rank : 39)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	114	Target Neighborhood Hits	918	Shared Neighborhood Hits	49
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

DNJC3_HUMAN
NC score	0.056701 (rank : 40)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	114	Target Neighborhood Hits	223	Shared Neighborhood Hits	25
SwissProt Accessions	Q13217, Q86WT9, Q8N4N2	Gene names	DNAJC3, P58IPK, PRKRI
Domain Architecture	No domain graphic available
Description	DnaJ homolog subfamily C member 3 (Interferon-induced, double-stranded RNA-activated protein kinase inhibitor) (Protein kinase inhibitor p58) (Protein kinase inhibitor of 58 kDa).

GEMI_MOUSE
NC score	0.055920 (rank : 41)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	114	Target Neighborhood Hits	163	Shared Neighborhood Hits	21
SwissProt Accessions	O88513	Gene names	Gmnn
Domain Architecture
Description	Geminin.

CTR9_HUMAN
NC score	0.055357 (rank : 42)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	114	Target Neighborhood Hits	383	Shared Neighborhood Hits	52
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

CDC23_MOUSE
NC score	0.054682 (rank : 43)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	114	Target Neighborhood Hits	65	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BGZ4, Q8C0F1	Gene names	Cdc23
Domain Architecture
Description	Cell division cycle protein 23 homolog (Anaphase-promoting complex subunit 8) (APC8) (Cyclosome subunit 8).

CTR9_MOUSE
NC score	0.054495 (rank : 44)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	114	Target Neighborhood Hits	427	Shared Neighborhood Hits	51
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

TTC6_HUMAN
NC score	0.054116 (rank : 45)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	114	Target Neighborhood Hits	103	Shared Neighborhood Hits	23
SwissProt Accessions	Q86TZ1, Q96CE6	Gene names	TTC6
Domain Architecture
Description	Tetratricopeptide repeat protein 6 (TPR repeat protein 6).

EEA1_MOUSE
NC score	0.053978 (rank : 46)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	114	Target Neighborhood Hits	1637	Shared Neighborhood Hits	58
SwissProt Accessions	Q8BL66, Q6DIC2	Gene names	Eea1
Domain Architecture	No domain graphic available
Description	Early endosome antigen 1.

UTX_HUMAN
NC score	0.052905 (rank : 47)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	114	Target Neighborhood Hits	161	Shared Neighborhood Hits	20
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

SDCG8_MOUSE
NC score	0.051741 (rank : 48)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	114	Target Neighborhood Hits	886	Shared Neighborhood Hits	56
SwissProt Accessions	Q80UF4	Gene names	Sdccag8, Cccap
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (mCCCAP).

K1279_MOUSE
NC score	0.050116 (rank : 49)	θ value	0.62314 (rank : 29)
Query Neighborhood Hits	114	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZPU9, Q5BKR5, Q7TPE0, Q80VQ5, Q8BZE2, Q8CFS7	Gene names	Kiaa1279
Domain Architecture	No domain graphic available
Description	Protein KIAA1279.

SAS6_MOUSE
NC score	0.050104 (rank : 50)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	114	Target Neighborhood Hits	931	Shared Neighborhood Hits	54
SwissProt Accessions	Q80UK7, Q9CYT4	Gene names	Sass6, Sas6
Domain Architecture	No domain graphic available
Description	Spindle assembly abnormal protein 6 homolog.

SDCG8_HUMAN
NC score	0.049858 (rank : 51)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	114	Target Neighborhood Hits	1002	Shared Neighborhood Hits	55
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

UTY_HUMAN
NC score	0.048790 (rank : 52)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	114	Target Neighborhood Hits	89	Shared Neighborhood Hits	20
SwissProt Accessions	O14607, O14608	Gene names	UTY
Domain Architecture
Description	Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the Y chromosome).

EEA1_HUMAN
NC score	0.047851 (rank : 53)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	114	Target Neighborhood Hits	1796	Shared Neighborhood Hits	60
SwissProt Accessions	Q15075, Q14221	Gene names	EEA1, ZFYVE2
Domain Architecture
Description	Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2).

TPM1_MOUSE
NC score	0.046832 (rank : 54)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	114	Target Neighborhood Hits	729	Shared Neighborhood Hits	55
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

SYCP1_HUMAN
NC score	0.046632 (rank : 55)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	114	Target Neighborhood Hits	1313	Shared Neighborhood Hits	59
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

ITSN2_HUMAN
NC score	0.046546 (rank : 56)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	114	Target Neighborhood Hits	1173	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

RAD50_MOUSE
NC score	0.046322 (rank : 57)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	114	Target Neighborhood Hits	1366	Shared Neighborhood Hits	55
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

TPM1_HUMAN
NC score	0.045841 (rank : 58)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	114	Target Neighborhood Hits	716	Shared Neighborhood Hits	54
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

GOGB1_HUMAN
NC score	0.045618 (rank : 59)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	114	Target Neighborhood Hits	2297	Shared Neighborhood Hits	67
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CROCC_HUMAN
NC score	0.045611 (rank : 60)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	114	Target Neighborhood Hits	1409	Shared Neighborhood Hits	55
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

MY18A_MOUSE
NC score	0.045378 (rank : 61)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	114	Target Neighborhood Hits	1989	Shared Neighborhood Hits	62
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

GOGA4_HUMAN
NC score	0.044824 (rank : 62)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	114	Target Neighborhood Hits	2034	Shared Neighborhood Hits	68
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MY18A_HUMAN
NC score	0.044529 (rank : 63)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	114	Target Neighborhood Hits	1929	Shared Neighborhood Hits	62
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH11_MOUSE
NC score	0.044517 (rank : 64)	θ value	0.21417 (rank : 19)
Query Neighborhood Hits	114	Target Neighborhood Hits	1777	Shared Neighborhood Hits	61
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

RB6I2_HUMAN
NC score	0.044013 (rank : 65)	θ value	5.27518 (rank : 80)
Query Neighborhood Hits	114	Target Neighborhood Hits	1584	Shared Neighborhood Hits	59
SwissProt Accessions	Q8IUD2, Q6NVK2, Q8IUD3, Q8IUD4, Q8IUD5, Q8NAS1, Q9NXN5, Q9UIK7, Q9UPS1	Gene names	ERC1, ELKS, KIAA1081, RAB6IP2
Domain Architecture	No domain graphic available
Description	ELKS/RAB6-interacting/CAST family member 1 (RAB6-interacting protein 2) (ERC protein 1).

LIPA1_HUMAN
NC score	0.043910 (rank : 66)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	114	Target Neighborhood Hits	1294	Shared Neighborhood Hits	62
SwissProt Accessions	Q13136, Q13135, Q14567, Q8N4I2	Gene names	PPFIA1, LIP1
Domain Architecture
Description	Liprin-alpha-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1) (LAR-interacting protein 1) (LIP.1).

ANR18_HUMAN
NC score	0.043014 (rank : 67)	θ value	0.0563607 (rank : 9)
Query Neighborhood Hits	114	Target Neighborhood Hits	1106	Shared Neighborhood Hits	55
SwissProt Accessions	Q8IVF6, Q7Z468	Gene names	ANKRD18A, KIAA2015
Domain Architecture
Description	Ankyrin repeat domain-containing protein 18A.

RBCC1_HUMAN
NC score	0.042179 (rank : 68)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	114	Target Neighborhood Hits	1023	Shared Neighborhood Hits	53
SwissProt Accessions	Q8TDY2, Q8WVU9, Q92601	Gene names	RB1CC1, KIAA0203, RBICC
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1.

GOGA4_MOUSE
NC score	0.042164 (rank : 69)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	114	Target Neighborhood Hits	1939	Shared Neighborhood Hits	60
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

MYH11_HUMAN
NC score	0.041581 (rank : 70)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	114	Target Neighborhood Hits	1806	Shared Neighborhood Hits	62
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH6_MOUSE
NC score	0.041526 (rank : 71)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	114	Target Neighborhood Hits	1501	Shared Neighborhood Hits	66
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH6_HUMAN
NC score	0.040579 (rank : 72)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	114	Target Neighborhood Hits	1426	Shared Neighborhood Hits	61
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

LEO1_MOUSE
NC score	0.040465 (rank : 73)	θ value	0.0736092 (rank : 13)
Query Neighborhood Hits	114	Target Neighborhood Hits	946	Shared Neighborhood Hits	25
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

KNTC2_HUMAN
NC score	0.040092 (rank : 74)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	114	Target Neighborhood Hits	673	Shared Neighborhood Hits	52
SwissProt Accessions	O14777, Q6PJX2	Gene names	KNTC2, HEC, HEC1
Domain Architecture	No domain graphic available
Description	Kinetochore protein Hec1 (HsHec1) (Kinetochore-associated protein 2) (Highly expressed in cancer protein) (Retinoblastoma-associated protein HEC).

MYH7_HUMAN
NC score	0.039952 (rank : 75)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	114	Target Neighborhood Hits	1559	Shared Neighborhood Hits	63
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH9_MOUSE
NC score	0.039763 (rank : 76)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	114	Target Neighborhood Hits	1829	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

A4_HUMAN
NC score	0.038807 (rank : 77)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	114	Target Neighborhood Hits	274	Shared Neighborhood Hits	27
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

MYH10_MOUSE
NC score	0.038225 (rank : 78)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	114	Target Neighborhood Hits	1612	Shared Neighborhood Hits	66
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

TEKT1_HUMAN
NC score	0.038009 (rank : 79)	θ value	5.27518 (rank : 82)
Query Neighborhood Hits	114	Target Neighborhood Hits	289	Shared Neighborhood Hits	38
SwissProt Accessions	Q969V4	Gene names	TEKT1
Domain Architecture
Description	Tektin-1.

CASP_HUMAN
NC score	0.037626 (rank : 80)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	114	Target Neighborhood Hits	1131	Shared Neighborhood Hits	57
SwissProt Accessions	Q13948, Q53GU9, Q8TBS3	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Protein CASP.

KLC1_HUMAN
NC score	0.037592 (rank : 81)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	114	Target Neighborhood Hits	471	Shared Neighborhood Hits	45
SwissProt Accessions	Q07866, Q7RTM2, Q7RTM3, Q7RTM5, Q7RTP9, Q7RTQ5, Q86SF5, Q86TF5, Q86V74, Q86V75, Q86V76, Q86V77, Q86V78, Q86V79, Q96H62	Gene names	KNS2, KLC, KLC1
Domain Architecture
Description	Kinesin light chain 1 (KLC 1).

A4_MOUSE
NC score	0.036934 (rank : 82)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	114	Target Neighborhood Hits	275	Shared Neighborhood Hits	24
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

RAI14_MOUSE
NC score	0.033806 (rank : 83)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	114	Target Neighborhood Hits	1505	Shared Neighborhood Hits	53
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

CUTL1_HUMAN
NC score	0.033437 (rank : 84)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	114	Target Neighborhood Hits	1574	Shared Neighborhood Hits	57
SwissProt Accessions	P39880, Q6NYH4, Q9UEV5	Gene names	CUTL1
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).

KI21A_MOUSE
NC score	0.033017 (rank : 85)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	114	Target Neighborhood Hits	1317	Shared Neighborhood Hits	56
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

KI21A_HUMAN
NC score	0.032769 (rank : 86)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	114	Target Neighborhood Hits	1543	Shared Neighborhood Hits	58
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

ZN318_MOUSE
NC score	0.031746 (rank : 87)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	114	Target Neighborhood Hits	642	Shared Neighborhood Hits	38
SwissProt Accessions	Q99PP2, Q3TZL5, Q9JJ01	Gene names	Znf318, Tzf, Zfp318
Domain Architecture	No domain graphic available
Description	Zinc finger protein 318 (Testicular zinc finger protein).

ROCK1_MOUSE
NC score	0.031348 (rank : 88)	θ value	0.279714 (rank : 22)
Query Neighborhood Hits	114	Target Neighborhood Hits	2126	Shared Neighborhood Hits	64
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

MKL1_MOUSE
NC score	0.030885 (rank : 89)	θ value	0.62314 (rank : 30)
Query Neighborhood Hits	114	Target Neighborhood Hits	667	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

KIF23_HUMAN
NC score	0.030760 (rank : 90)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	114	Target Neighborhood Hits	618	Shared Neighborhood Hits	48
SwissProt Accessions	Q02241	Gene names	KIF23, KNSL5, MKLP1
Domain Architecture
Description	Kinesin-like protein KIF23 (Mitotic kinesin-like protein 1) (Kinesin- like protein 5).

WDR19_HUMAN
NC score	0.030048 (rank : 91)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	114	Target Neighborhood Hits	88	Shared Neighborhood Hits	6
SwissProt Accessions	Q8NEZ3, Q8N5B4, Q9H5S0, Q9HCD4	Gene names	WDR19, KIAA1638
Domain Architecture	No domain graphic available
Description	WD repeat protein 19.

ANR12_HUMAN
NC score	0.029258 (rank : 92)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	114	Target Neighborhood Hits	1081	Shared Neighborhood Hits	56
SwissProt Accessions	Q6UB98, O94951, Q658K1, Q6QMF7, Q9H231, Q9H784	Gene names	ANKRD12, ANCO2, KIAA0874
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 12 (Ankyrin repeat-containing cofactor 2) (GAC-1 protein).

RF1M_MOUSE
NC score	0.028622 (rank : 93)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	114	Target Neighborhood Hits	54	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K126	Gene names	Mtrf1
Domain Architecture
Description	Peptide chain release factor 1, mitochondrial precursor (MRF-1).

FRG1_MOUSE
NC score	0.028155 (rank : 94)	θ value	5.27518 (rank : 79)
Query Neighborhood Hits	114	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	P97376, Q99M42	Gene names	Frg1
Domain Architecture
Description	Protein FRG1 (FSHD region gene 1 protein).

MTSS1_HUMAN
NC score	0.027279 (rank : 95)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	114	Target Neighborhood Hits	504	Shared Neighborhood Hits	22
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

CP26A_MOUSE
NC score	0.024626 (rank : 96)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	114	Target Neighborhood Hits	111	Shared Neighborhood Hits	4
SwissProt Accessions	O55127, Q9R1F4	Gene names	Cyp26a1, Cyp26, P450ra
Domain Architecture
Description	Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic acid-metabolizing cytochrome) (P450RAI) (Retinoic acid 4-hydroxylase).

VPS53_HUMAN
NC score	0.024571 (rank : 97)	θ value	5.27518 (rank : 83)
Query Neighborhood Hits	114	Target Neighborhood Hits	107	Shared Neighborhood Hits	15
SwissProt Accessions	Q5VIR6, Q8WYW3, Q9BRR2, Q9BY02, Q9NV25	Gene names	VPS53
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 53.

AN32E_HUMAN
NC score	0.023938 (rank : 98)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	114	Target Neighborhood Hits	291	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BTT0, Q8N1S4, Q8WWW9	Gene names	ANP32E
Domain Architecture	No domain graphic available
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L).

VPS53_MOUSE
NC score	0.023880 (rank : 99)	θ value	5.27518 (rank : 84)
Query Neighborhood Hits	114	Target Neighborhood Hits	102	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CCB4, Q8C7U0, Q8CIA1, Q9CX82, Q9D6T7	Gene names	Vps53
Domain Architecture	No domain graphic available
Description	Vacuolar protein sorting-associated protein 53.

KIF11_HUMAN
NC score	0.023821 (rank : 100)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	114	Target Neighborhood Hits	583	Shared Neighborhood Hits	45
SwissProt Accessions	P52732, Q15716, Q5VWX0	Gene names	KIF11, EG5, KNSL1
Domain Architecture
Description	Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5) (Kinesin-like spindle protein HKSP) (Thyroid receptor-interacting protein 5) (TRIP5) (Kinesin-like protein 1).

IFIT2_HUMAN
NC score	0.023715 (rank : 101)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	114	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	P09913	Gene names	IFIT2, G10P2, IFI54
Domain Architecture
Description	Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2) (Interferon-induced 54 kDa protein) (IFI-54K) (ISG-54 K).

ROCK2_HUMAN
NC score	0.023675 (rank : 102)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	114	Target Neighborhood Hits	2073	Shared Neighborhood Hits	61
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

AN32E_MOUSE
NC score	0.022904 (rank : 103)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	114	Target Neighborhood Hits	257	Shared Neighborhood Hits	12
SwissProt Accessions	P97822, Q3TH89, Q8BPF8, Q8C2L4, Q8C7Q8, Q9CZD2	Gene names	Anp32e, Cpd1
Domain Architecture
Description	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP- like protein) (LANP-L) (Cerebellar postnatal development protein 1).

LSD1_MOUSE
NC score	0.022888 (rank : 104)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	114	Target Neighborhood Hits	224	Shared Neighborhood Hits	26
SwissProt Accessions	Q6ZQ88, Q6PB53, Q8VEA1	Gene names	Aof2, Kiaa0601, Lsd1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

BPIL1_MOUSE
NC score	0.022714 (rank : 105)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	114	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C1E1, Q3TUY4, Q8BVZ0, Q8C1E2, Q9D713, Q9D744	Gene names	Bpil1
Domain Architecture
Description	Bactericidal/permeability-increasing protein-like 1 precursor.

FRG1_HUMAN
NC score	0.022574 (rank : 106)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	114	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q14331	Gene names	FRG1
Domain Architecture
Description	Protein FRG1 (FSHD region gene 1 protein).

LEO1_HUMAN
NC score	0.022120 (rank : 107)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	114	Target Neighborhood Hits	958	Shared Neighborhood Hits	26
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

ANR21_HUMAN
NC score	0.022017 (rank : 108)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	114	Target Neighborhood Hits	864	Shared Neighborhood Hits	46
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

CP26A_HUMAN
NC score	0.021838 (rank : 109)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	114	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	O43174	Gene names	CYP26A1, CYP26, P450RAI1
Domain Architecture
Description	Cytochrome P450 26A1 (EC 1.14.-.-) (Retinoic acid-metabolizing cytochrome) (P450 retinoic acid-inactivating 1) (P450RAI) (hP450RAI) (Retinoic acid 4-hydroxylase).

STK10_MOUSE
NC score	0.021620 (rank : 110)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	114	Target Neighborhood Hits	2132	Shared Neighborhood Hits	60
SwissProt Accessions	O55098	Gene names	Stk10, Lok
Domain Architecture
Description	Serine/threonine-protein kinase 10 (EC 2.7.11.1) (Lymphocyte-oriented kinase).

POT15_HUMAN
NC score	0.021348 (rank : 111)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	114	Target Neighborhood Hits	893	Shared Neighborhood Hits	47
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

LSD1_HUMAN
NC score	0.021327 (rank : 112)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	114	Target Neighborhood Hits	455	Shared Neighborhood Hits	26
SwissProt Accessions	O60341, Q5TH94, Q5TH95, Q86VT7, Q8IXK4, Q8NDP6, Q8TAZ3, Q96AW4	Gene names	AOF2, KIAA0601, LSD1
Domain Architecture	No domain graphic available
Description	Lysine-specific histone demethylase 1 (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 2) (BRAF35-HDAC complex protein BHC110).

WDR19_MOUSE
NC score	0.021302 (rank : 113)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	114	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q3UGF1, Q6ZPK8, Q80VQ6, Q8C794, Q8K3R5	Gene names	Wdr19, Kiaa1638
Domain Architecture	No domain graphic available
Description	WD repeat protein 19.

KI67_HUMAN
NC score	0.018661 (rank : 114)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	114	Target Neighborhood Hits	581	Shared Neighborhood Hits	16
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

GGT1_MOUSE
NC score	0.016634 (rank : 115)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	114	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q60928	Gene names	Ggt1, Ggt, Ggtp
Domain Architecture
Description	Gamma-glutamyltranspeptidase 1 precursor (EC 2.3.2.2) (Gamma- glutamyltransferase 1) (GGT 1) (CD224 antigen) [Contains: Gamma- glutamyltranspeptidase 1 heavy chain; Gamma-glutamyltranspeptidase 1 light chain].

FANCG_MOUSE
NC score	0.011324 (rank : 116)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	114	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQR6	Gene names	Fancg
Domain Architecture	No domain graphic available
Description	Fanconi anemia group G protein homolog (Protein FACG).

LY10_HUMAN
NC score	0.010671 (rank : 117)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	114	Target Neighborhood Hits	151	Shared Neighborhood Hits	4
SwissProt Accessions	Q13342, Q13341, Q92881, Q96TG3	Gene names	SP140, LYSP100
Domain Architecture
Description	Nuclear body protein SP140 (Nuclear autoantigen Sp-140) (Speckled 140 kDa) (LYSp100 protein) (Lymphoid-restricted homolog of Sp100).

STK6_HUMAN
NC score	0.009199 (rank : 118)	θ value	0.365318 (rank : 25)
Query Neighborhood Hits	114	Target Neighborhood Hits	916	Shared Neighborhood Hits	9
SwissProt Accessions	O14965, O60445, O75873, Q9BQD6, Q9UPG5	Gene names	STK6, AIK, ARK1, AURA, BTAK, STK15
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Serine/threonine kinase 15) (Aurora/IPL1-related kinase 1) (Aurora-related kinase 1) (hARK1) (Aurora-A) (Breast-tumor-amplified kinase).

STK6_MOUSE
NC score	0.008864 (rank : 119)	θ value	0.47712 (rank : 27)
Query Neighborhood Hits	114	Target Neighborhood Hits	886	Shared Neighborhood Hits	8
SwissProt Accessions	P97477, O35624, Q91YU4	Gene names	Stk6, Ark1, Aurka, Ayk1, Iak1
Domain Architecture
Description	Serine/threonine-protein kinase 6 (EC 2.7.11.1) (Aurora-family kinase 1) (Aurora/IPL1-related kinase 1) (Ipl1- and aurora-related kinase 1) (Aurora-A) (Serine/threonine-protein kinase Ayk1).

AURKB_MOUSE
NC score	0.005534 (rank : 120)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	114	Target Neighborhood Hits	858	Shared Neighborhood Hits	8
SwissProt Accessions	O70126, Q61882	Gene names	Aurkb, Ark2, Stk1, Stk12, Stk5
Domain Architecture
Description	Serine/threonine-protein kinase 12 (EC 2.7.11.1) (Aurora-B) (Aurora- related kinase 2) (Serine/threonine-protein kinase 5) (STK-1).

UBE3A_MOUSE
NC score	0.004213 (rank : 121)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	114	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).