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Network neighborhood for query Sequence : SPFH1_HUMAN

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SPFH1_HUMAN
SwissProt Accessions	O75477	Gene names	SPFH1, C10orf69, KE04, KEO4
Domain Architecture	No domain graphic available
Description	SPFH domain-containing protein 1 precursor (Protein KE04).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SPFH1_HUMAN
θ value	2.17943e-171 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	91	Target Neighborhood Hits	91	Shared Neighborhood Hits	91
SwissProt Accessions	O75477	Gene names	SPFH1, C10orf69, KE04, KEO4
Domain Architecture	No domain graphic available
Description	SPFH domain-containing protein 1 precursor (Protein KE04).

SPFH1_MOUSE
θ value	1.51281e-164 (rank : 2)	NC score	0.994873 (rank : 2)
Query Neighborhood Hits	91	Target Neighborhood Hits	86	Shared Neighborhood Hits	73
SwissProt Accessions	Q91X78, Q8CIH7	Gene names	Spfh1, Keo4
Domain Architecture	No domain graphic available
Description	SPFH domain-containing protein 1 precursor (KE04 protein homolog).

SPFH2_HUMAN
θ value	3.89193e-128 (rank : 3)	NC score	0.975631 (rank : 4)
Query Neighborhood Hits	91	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	O94905, Q6NW21, Q86VS6, Q86W49	Gene names	SPFH2, C8orf2
Domain Architecture
Description	SPFH domain-containing protein 2 precursor.

SPFH2_MOUSE
θ value	3.89193e-128 (rank : 4)	NC score	0.975972 (rank : 3)
Query Neighborhood Hits	91	Target Neighborhood Hits	39	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BFZ9, Q8BML8	Gene names	Spfh2
Domain Architecture	No domain graphic available
Description	SPFH domain-containing protein 2 precursor.

TAF3_HUMAN
θ value	0.0252991 (rank : 5)	NC score	0.104555 (rank : 11)
Query Neighborhood Hits	91	Target Neighborhood Hits	568	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

CAF1A_HUMAN
θ value	0.0431538 (rank : 6)	NC score	0.088412 (rank : 14)
Query Neighborhood Hits	91	Target Neighborhood Hits	750	Shared Neighborhood Hits	41
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

MED4_HUMAN
θ value	0.0563607 (rank : 7)	NC score	0.117724 (rank : 7)
Query Neighborhood Hits	91	Target Neighborhood Hits	96	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPJ6, Q5T912, Q6FHC4, Q6IA79, Q9BS95, Q9NYR5	Gene names	MED4, ARC36, DRIP36, VDRIP
Domain Architecture	No domain graphic available
Description	Mediator complex subunit 4 (Mediator of RNA polymerase II transcription subunit 4) (Vitamin D3 receptor-interacting protein complex 36 kDa component) (DRIP36) (Activator-recruited cofactor 36 kDa component) (ARC36) (TRAP/SMCC/PC2 subunit p36 subunit).

STML3_MOUSE
θ value	0.0736092 (rank : 8)	NC score	0.115274 (rank : 9)
Query Neighborhood Hits	91	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PE84, Q66JM3, Q8K4P4	Gene names	Stoml3, Sro
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 3 (Stomatin-related olfactory protein).

STML3_HUMAN
θ value	0.0961366 (rank : 9)	NC score	0.114103 (rank : 10)
Query Neighborhood Hits	91	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TAV4, Q5JS35	Gene names	STOML3
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 3.

JIP3_HUMAN
θ value	0.125558 (rank : 10)	NC score	0.073203 (rank : 20)
Query Neighborhood Hits	91	Target Neighborhood Hits	1039	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

PODO_HUMAN
θ value	0.125558 (rank : 11)	NC score	0.157287 (rank : 5)
Query Neighborhood Hits	91	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NP85, Q8N6Q5	Gene names	NPHS2
Domain Architecture
Description	Podocin.

PODO_MOUSE
θ value	0.125558 (rank : 12)	NC score	0.156202 (rank : 6)
Query Neighborhood Hits	91	Target Neighborhood Hits	29	Shared Neighborhood Hits	12
SwissProt Accessions	Q91X05, Q8BWE6, Q91Z95	Gene names	Nphs2
Domain Architecture
Description	Podocin.

SRGP1_HUMAN
θ value	0.125558 (rank : 13)	NC score	0.037529 (rank : 55)
Query Neighborhood Hits	91	Target Neighborhood Hits	390	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

GBP2_MOUSE
θ value	0.163984 (rank : 14)	NC score	0.034321 (rank : 62)
Query Neighborhood Hits	91	Target Neighborhood Hits	323	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z0E6, Q8CIC6, Q921N2, Q9R1I0	Gene names	Gbp2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (mGBP2) (mGBP-2).

CK5P3_MOUSE
θ value	0.279714 (rank : 15)	NC score	0.086822 (rank : 16)
Query Neighborhood Hits	91	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	Q99LM2, Q3UE41	Gene names	Cdk5rap3
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 3.

MAP9_MOUSE
θ value	0.279714 (rank : 16)	NC score	0.068848 (rank : 23)
Query Neighborhood Hits	91	Target Neighborhood Hits	529	Shared Neighborhood Hits	22
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

PEPL_HUMAN
θ value	0.365318 (rank : 17)	NC score	0.052296 (rank : 31)
Query Neighborhood Hits	91	Target Neighborhood Hits	1141	Shared Neighborhood Hits	52
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

STOM_HUMAN
θ value	0.365318 (rank : 18)	NC score	0.117295 (rank : 8)
Query Neighborhood Hits	91	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	P27105, Q14087, Q15609, Q5VX96, Q96FK4	Gene names	STOM, BND7, EPB72
Domain Architecture
Description	Erythrocyte band 7 integral membrane protein (Stomatin) (Protein 7.2b).

CEP55_MOUSE
θ value	0.62314 (rank : 19)	NC score	0.051216 (rank : 33)
Query Neighborhood Hits	91	Target Neighborhood Hits	693	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

PHLB2_HUMAN
θ value	0.62314 (rank : 20)	NC score	0.056788 (rank : 28)
Query Neighborhood Hits	91	Target Neighborhood Hits	964	Shared Neighborhood Hits	53
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

MAP9_HUMAN
θ value	0.813845 (rank : 21)	NC score	0.065070 (rank : 26)
Query Neighborhood Hits	91	Target Neighborhood Hits	518	Shared Neighborhood Hits	26
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

PHB2_HUMAN
θ value	0.813845 (rank : 22)	NC score	0.074948 (rank : 18)
Query Neighborhood Hits	91	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q99623, Q7KYU3, Q92978	Gene names	PHB2, BAP, REA
Domain Architecture	No domain graphic available
Description	Prohibitin-2 (B-cell receptor-associated protein BAP37) (Repressor of estrogen receptor activity) (D-prohibitin).

PHB2_MOUSE
θ value	0.813845 (rank : 23)	NC score	0.074948 (rank : 19)
Query Neighborhood Hits	91	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	O35129, O89075, Q61336	Gene names	Phb2, Bap, Bcap37, Rea
Domain Architecture	No domain graphic available
Description	Prohibitin-2 (B-cell receptor-associated protein BAP37) (Repressor of estrogen receptor activity).

PLEC1_HUMAN
θ value	0.813845 (rank : 24)	NC score	0.039533 (rank : 50)
Query Neighborhood Hits	91	Target Neighborhood Hits	1326	Shared Neighborhood Hits	55
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

MED4_MOUSE
θ value	1.06291 (rank : 25)	NC score	0.084591 (rank : 17)
Query Neighborhood Hits	91	Target Neighborhood Hits	124	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CQA5	Gene names	Med4, Vdrip
Domain Architecture	No domain graphic available
Description	Mediator complex subunit 4 (Mediator of RNA polymerase II transcription subunit 4).

MYO6_HUMAN
θ value	1.06291 (rank : 26)	NC score	0.035425 (rank : 60)
Query Neighborhood Hits	91	Target Neighborhood Hits	727	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

TUFT1_HUMAN
θ value	1.06291 (rank : 27)	NC score	0.048116 (rank : 34)
Query Neighborhood Hits	91	Target Neighborhood Hits	686	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

UBP8_HUMAN
θ value	1.06291 (rank : 28)	NC score	0.024937 (rank : 83)
Query Neighborhood Hits	91	Target Neighborhood Hits	751	Shared Neighborhood Hits	38
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

CE290_HUMAN
θ value	1.38821 (rank : 29)	NC score	0.047110 (rank : 36)
Query Neighborhood Hits	91	Target Neighborhood Hits	1553	Shared Neighborhood Hits	63
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

FLOT2_HUMAN
θ value	1.38821 (rank : 30)	NC score	0.100194 (rank : 13)
Query Neighborhood Hits	91	Target Neighborhood Hits	87	Shared Neighborhood Hits	19
SwissProt Accessions	Q14254	Gene names	FLOT2, ESA1, M17S1
Domain Architecture
Description	Flotillin-2 (Epidermal surface antigen) (ESA).

FLOT2_MOUSE
θ value	1.38821 (rank : 31)	NC score	0.100622 (rank : 12)
Query Neighborhood Hits	91	Target Neighborhood Hits	90	Shared Neighborhood Hits	21
SwissProt Accessions	Q60634, Q6NS75	Gene names	Flot2, Esa1, M17s1
Domain Architecture
Description	Flotillin-2 (Epidermal surface antigen) (ESA).

MYH10_MOUSE
θ value	1.38821 (rank : 32)	NC score	0.037938 (rank : 53)
Query Neighborhood Hits	91	Target Neighborhood Hits	1612	Shared Neighborhood Hits	62
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH13_HUMAN
θ value	1.38821 (rank : 33)	NC score	0.034180 (rank : 63)
Query Neighborhood Hits	91	Target Neighborhood Hits	1504	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

CK5P3_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.071185 (rank : 21)
Query Neighborhood Hits	91	Target Neighborhood Hits	38	Shared Neighborhood Hits	10
SwissProt Accessions	Q96JB5, Q53FA2, Q9H3F8, Q9H8G0, Q9HBR9	Gene names	CDK5RAP3, IC53
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 3 (CDK5 activator-binding protein C53) (HSF-27 protein).

HGS_MOUSE
θ value	1.81305 (rank : 35)	NC score	0.026323 (rank : 81)
Query Neighborhood Hits	91	Target Neighborhood Hits	589	Shared Neighborhood Hits	13
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

MERL_HUMAN
θ value	1.81305 (rank : 36)	NC score	0.033058 (rank : 66)
Query Neighborhood Hits	91	Target Neighborhood Hits	532	Shared Neighborhood Hits	42
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

MERL_MOUSE
θ value	1.81305 (rank : 37)	NC score	0.033483 (rank : 65)
Query Neighborhood Hits	91	Target Neighborhood Hits	524	Shared Neighborhood Hits	43
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MYH10_HUMAN
θ value	1.81305 (rank : 38)	NC score	0.037556 (rank : 54)
Query Neighborhood Hits	91	Target Neighborhood Hits	1620	Shared Neighborhood Hits	63
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH14_MOUSE
θ value	1.81305 (rank : 39)	NC score	0.035222 (rank : 61)
Query Neighborhood Hits	91	Target Neighborhood Hits	1225	Shared Neighborhood Hits	52
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

PABP4_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.016029 (rank : 92)
Query Neighborhood Hits	91	Target Neighborhood Hits	268	Shared Neighborhood Hits	5
SwissProt Accessions	Q13310, Q6P0N3	Gene names	PABPC4, APP1, PABP4
Domain Architecture
Description	Polyadenylate-binding protein 4 (Poly(A)-binding protein 4) (PABP 4) (Inducible poly(A)-binding protein) (iPABP) (Activated-platelet protein 1) (APP-1).

TRI35_HUMAN
θ value	1.81305 (rank : 41)	NC score	0.032359 (rank : 68)
Query Neighborhood Hits	91	Target Neighborhood Hits	382	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

CENPE_HUMAN
θ value	2.36792 (rank : 42)	NC score	0.032612 (rank : 67)
Query Neighborhood Hits	91	Target Neighborhood Hits	2060	Shared Neighborhood Hits	67
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

K1C10_HUMAN
θ value	2.36792 (rank : 43)	NC score	0.016749 (rank : 89)
Query Neighborhood Hits	91	Target Neighborhood Hits	526	Shared Neighborhood Hits	30
SwissProt Accessions	P13645, Q14664, Q8N175	Gene names	KRT10
Domain Architecture
Description	Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10).

MVP_HUMAN
θ value	2.36792 (rank : 44)	NC score	0.046949 (rank : 37)
Query Neighborhood Hits	91	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	Q14764, Q96BG4, Q9BPW6, Q9BQT1, Q9UBD1	Gene names	MVP, LRP
Domain Architecture
Description	Major vault protein (MVP) (Lung resistance-related protein).

PHLB2_MOUSE
θ value	2.36792 (rank : 45)	NC score	0.051771 (rank : 32)
Query Neighborhood Hits	91	Target Neighborhood Hits	1016	Shared Neighborhood Hits	56
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

TAF3_MOUSE
θ value	2.36792 (rank : 46)	NC score	0.057163 (rank : 27)
Query Neighborhood Hits	91	Target Neighborhood Hits	463	Shared Neighborhood Hits	22
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

AZI1_HUMAN
θ value	3.0926 (rank : 47)	NC score	0.038928 (rank : 52)
Query Neighborhood Hits	91	Target Neighborhood Hits	1000	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

FLOT1_MOUSE
θ value	3.0926 (rank : 48)	NC score	0.067475 (rank : 24)
Query Neighborhood Hits	91	Target Neighborhood Hits	128	Shared Neighborhood Hits	22
SwissProt Accessions	O08917	Gene names	Flot1
Domain Architecture
Description	Flotillin-1.

KMHN1_HUMAN
θ value	3.0926 (rank : 49)	NC score	0.034108 (rank : 64)
Query Neighborhood Hits	91	Target Neighborhood Hits	950	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

NOL8_MOUSE
θ value	3.0926 (rank : 50)	NC score	0.043018 (rank : 42)
Query Neighborhood Hits	91	Target Neighborhood Hits	210	Shared Neighborhood Hits	11
SwissProt Accessions	Q3UHX0, Q504M4, Q8CDJ7, Q9CUR0	Gene names	Nol8
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8.

TRIM1_HUMAN
θ value	3.0926 (rank : 51)	NC score	0.016240 (rank : 90)
Query Neighborhood Hits	91	Target Neighborhood Hits	345	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
θ value	3.0926 (rank : 52)	NC score	0.016104 (rank : 91)
Query Neighborhood Hits	91	Target Neighborhood Hits	361	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

VDP_HUMAN
θ value	3.0926 (rank : 53)	NC score	0.045193 (rank : 39)
Query Neighborhood Hits	91	Target Neighborhood Hits	645	Shared Neighborhood Hits	34
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

BRE1A_MOUSE
θ value	4.03905 (rank : 54)	NC score	0.029096 (rank : 72)
Query Neighborhood Hits	91	Target Neighborhood Hits	1025	Shared Neighborhood Hits	44
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

GOGA4_MOUSE
θ value	4.03905 (rank : 55)	NC score	0.040394 (rank : 48)
Query Neighborhood Hits	91	Target Neighborhood Hits	1939	Shared Neighborhood Hits	75
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

LRC59_HUMAN
θ value	4.03905 (rank : 56)	NC score	0.022115 (rank : 86)
Query Neighborhood Hits	91	Target Neighborhood Hits	398	Shared Neighborhood Hits	12
SwissProt Accessions	Q96AG4, Q9P189	Gene names	LRRC59
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 59.

NOL8_HUMAN
θ value	4.03905 (rank : 57)	NC score	0.028406 (rank : 75)
Query Neighborhood Hits	91	Target Neighborhood Hits	297	Shared Neighborhood Hits	10
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

OPTN_MOUSE
θ value	4.03905 (rank : 58)	NC score	0.042840 (rank : 43)
Query Neighborhood Hits	91	Target Neighborhood Hits	1120	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

PEPL_MOUSE
θ value	4.03905 (rank : 59)	NC score	0.042377 (rank : 45)
Query Neighborhood Hits	91	Target Neighborhood Hits	1105	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

PIBF1_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.039061 (rank : 51)
Query Neighborhood Hits	91	Target Neighborhood Hits	1041	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

SDS3_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.040072 (rank : 49)
Query Neighborhood Hits	91	Target Neighborhood Hits	248	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BR65, Q3UC92, Q6P6K1, Q7TNT0, Q8BRR7, Q8K5B4	Gene names	Suds3, Sds3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

SYCP1_MOUSE
θ value	4.03905 (rank : 62)	NC score	0.041550 (rank : 46)
Query Neighborhood Hits	91	Target Neighborhood Hits	1456	Shared Neighborhood Hits	60
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TBC14_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.023639 (rank : 84)
Query Neighborhood Hits	91	Target Neighborhood Hits	124	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P2M4, Q8IW15	Gene names	TBC1D14, KIAA1322
Domain Architecture
Description	TBC1 domain family member 14.

TPX2_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.044578 (rank : 41)
Query Neighborhood Hits	91	Target Neighborhood Hits	150	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULW0, Q9H1R4, Q9NRA3, Q9UFN9, Q9UL00, Q9Y2M1	Gene names	TPX2, C20orf1, C20orf2, DIL2, HCA519
Domain Architecture	No domain graphic available
Description	Targeting protein for Xklp2 (Restricted expression proliferation- associated protein 100) (p100) (Differentially expressed in cancerous and noncancerous lung cells 2) (DIL-2) (Protein FLS353) (Hepatocellular carcinoma-associated antigen 519).

TRDN_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.028279 (rank : 78)
Query Neighborhood Hits	91	Target Neighborhood Hits	542	Shared Neighborhood Hits	22
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

BAZ2A_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.014941 (rank : 93)
Query Neighborhood Hits	91	Target Neighborhood Hits	780	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

CCD55_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.044746 (rank : 40)
Query Neighborhood Hits	91	Target Neighborhood Hits	513	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

CENPH_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.040915 (rank : 47)
Query Neighborhood Hits	91	Target Neighborhood Hits	195	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYM8, Q8R3K9, Q9D079, Q9D0N1	Gene names	Cenph, Enp
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H).

JIP3_MOUSE
θ value	5.27518 (rank : 69)	NC score	0.047235 (rank : 35)
Query Neighborhood Hits	91	Target Neighborhood Hits	759	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

MVP_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.042552 (rank : 44)
Query Neighborhood Hits	91	Target Neighborhood Hits	98	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EQK5	Gene names	Mvp
Domain Architecture
Description	Major vault protein (MVP).

MYH14_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.031811 (rank : 69)
Query Neighborhood Hits	91	Target Neighborhood Hits	995	Shared Neighborhood Hits	42
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

TPM3_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.029623 (rank : 71)
Query Neighborhood Hits	91	Target Neighborhood Hits	689	Shared Neighborhood Hits	33
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

TPM3_MOUSE
θ value	5.27518 (rank : 73)	NC score	0.028941 (rank : 73)
Query Neighborhood Hits	91	Target Neighborhood Hits	676	Shared Neighborhood Hits	34
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

CCD55_MOUSE
θ value	6.88961 (rank : 74)	NC score	0.025909 (rank : 82)
Query Neighborhood Hits	91	Target Neighborhood Hits	519	Shared Neighborhood Hits	19
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

GOGB1_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.035425 (rank : 59)
Query Neighborhood Hits	91	Target Neighborhood Hits	2297	Shared Neighborhood Hits	70
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

LRC59_MOUSE
θ value	6.88961 (rank : 76)	NC score	0.019782 (rank : 88)
Query Neighborhood Hits	91	Target Neighborhood Hits	415	Shared Neighborhood Hits	16
SwissProt Accessions	Q922Q8, Q3TJ35, Q3TLC7, Q3TWT9, Q3TX86	Gene names	Lrrc59
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 59.

STIM1_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.036703 (rank : 56)
Query Neighborhood Hits	91	Target Neighborhood Hits	665	Shared Neighborhood Hits	48
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

SYCP1_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.045881 (rank : 38)
Query Neighborhood Hits	91	Target Neighborhood Hits	1313	Shared Neighborhood Hits	59
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TBC12_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.022213 (rank : 85)
Query Neighborhood Hits	91	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	O60347, Q5VYA6, Q8WX26, Q8WX59, Q9UG83	Gene names	TBC1D12, KIAA0608
Domain Architecture
Description	TBC1 domain family member 12.

TRI35_MOUSE
θ value	6.88961 (rank : 80)	NC score	0.028351 (rank : 77)
Query Neighborhood Hits	91	Target Neighborhood Hits	465	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

ACINU_HUMAN
θ value	8.99809 (rank : 81)	NC score	0.027806 (rank : 79)
Query Neighborhood Hits	91	Target Neighborhood Hits	828	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CALD1_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.030584 (rank : 70)
Query Neighborhood Hits	91	Target Neighborhood Hits	959	Shared Neighborhood Hits	44
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

JAD1A_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.010978 (rank : 94)
Query Neighborhood Hits	91	Target Neighborhood Hits	328	Shared Neighborhood Hits	19
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

MACF1_MOUSE
θ value	8.99809 (rank : 84)	NC score	0.035492 (rank : 58)
Query Neighborhood Hits	91	Target Neighborhood Hits	1313	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MOES_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.026608 (rank : 80)
Query Neighborhood Hits	91	Target Neighborhood Hits	923	Shared Neighborhood Hits	47
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

MYO6_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.028748 (rank : 74)
Query Neighborhood Hits	91	Target Neighborhood Hits	586	Shared Neighborhood Hits	39
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

OTU6B_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.028394 (rank : 76)
Query Neighborhood Hits	91	Target Neighborhood Hits	202	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K2H2	Gene names	Otud6b
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 6B.

SDS3_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.035796 (rank : 57)
Query Neighborhood Hits	91	Target Neighborhood Hits	257	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H7L9, Q8N6H0, Q9H8D2	Gene names	SUDS3, SDS3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

STML1_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.066828 (rank : 25)
Query Neighborhood Hits	91	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBI4, O95675, Q6FGL8, Q8WYI7, Q9UMB9, Q9UMC0, Q9Y6H9	Gene names	STOML1, SLP1, UNC24
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 1 (SLP-1) (Stomatin-related protein) (STORP) (EPB72-like 1) (UNC24 homolog).

STML1_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.068946 (rank : 22)
Query Neighborhood Hits	91	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CI66, Q8BLA3	Gene names	Stoml1
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 1 (SLP-1).

TEKT1_MOUSE
θ value	8.99809 (rank : 91)	NC score	0.022031 (rank : 87)
Query Neighborhood Hits	91	Target Neighborhood Hits	399	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DAJ2	Gene names	Tekt1
Domain Architecture
Description	Tektin-1.

STML2_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.055102 (rank : 29)
Query Neighborhood Hits	91	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UJZ1, O60376, Q53G29, Q96FY2, Q9P042	Gene names	STOML2, SLP2
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 2 (SLP-2) (EPB72-like 2).

STML2_MOUSE
θ value	θ > 10 (rank : 93)	NC score	0.054899 (rank : 30)
Query Neighborhood Hits	91	Target Neighborhood Hits	23	Shared Neighborhood Hits	10
SwissProt Accessions	Q99JB2, Q9DCG8	Gene names	Stoml2, Slp2
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 2 (SLP-2).

STOM_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.087410 (rank : 15)
Query Neighborhood Hits	91	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	P54116, Q60744, Q62455	Gene names	Stom, Epb7.2, Epb72
Domain Architecture
Description	Erythrocyte band 7 integral membrane protein (Stomatin) (Protein 7.2b).

Hits sorted by NC score

SPFH1_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.17943e-171 (rank : 1)
Query Neighborhood Hits	91	Target Neighborhood Hits	91	Shared Neighborhood Hits	91
SwissProt Accessions	O75477	Gene names	SPFH1, C10orf69, KE04, KEO4
Domain Architecture	No domain graphic available
Description	SPFH domain-containing protein 1 precursor (Protein KE04).

SPFH1_MOUSE
NC score	0.994873 (rank : 2)	θ value	1.51281e-164 (rank : 2)
Query Neighborhood Hits	91	Target Neighborhood Hits	86	Shared Neighborhood Hits	73
SwissProt Accessions	Q91X78, Q8CIH7	Gene names	Spfh1, Keo4
Domain Architecture	No domain graphic available
Description	SPFH domain-containing protein 1 precursor (KE04 protein homolog).

SPFH2_MOUSE
NC score	0.975972 (rank : 3)	θ value	3.89193e-128 (rank : 4)
Query Neighborhood Hits	91	Target Neighborhood Hits	39	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BFZ9, Q8BML8	Gene names	Spfh2
Domain Architecture	No domain graphic available
Description	SPFH domain-containing protein 2 precursor.

SPFH2_HUMAN
NC score	0.975631 (rank : 4)	θ value	3.89193e-128 (rank : 3)
Query Neighborhood Hits	91	Target Neighborhood Hits	38	Shared Neighborhood Hits	23
SwissProt Accessions	O94905, Q6NW21, Q86VS6, Q86W49	Gene names	SPFH2, C8orf2
Domain Architecture
Description	SPFH domain-containing protein 2 precursor.

PODO_HUMAN
NC score	0.157287 (rank : 5)	θ value	0.125558 (rank : 11)
Query Neighborhood Hits	91	Target Neighborhood Hits	44	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NP85, Q8N6Q5	Gene names	NPHS2
Domain Architecture
Description	Podocin.

PODO_MOUSE
NC score	0.156202 (rank : 6)	θ value	0.125558 (rank : 12)
Query Neighborhood Hits	91	Target Neighborhood Hits	29	Shared Neighborhood Hits	12
SwissProt Accessions	Q91X05, Q8BWE6, Q91Z95	Gene names	Nphs2
Domain Architecture
Description	Podocin.

MED4_HUMAN
NC score	0.117724 (rank : 7)	θ value	0.0563607 (rank : 7)
Query Neighborhood Hits	91	Target Neighborhood Hits	96	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPJ6, Q5T912, Q6FHC4, Q6IA79, Q9BS95, Q9NYR5	Gene names	MED4, ARC36, DRIP36, VDRIP
Domain Architecture	No domain graphic available
Description	Mediator complex subunit 4 (Mediator of RNA polymerase II transcription subunit 4) (Vitamin D3 receptor-interacting protein complex 36 kDa component) (DRIP36) (Activator-recruited cofactor 36 kDa component) (ARC36) (TRAP/SMCC/PC2 subunit p36 subunit).

STOM_HUMAN
NC score	0.117295 (rank : 8)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	91	Target Neighborhood Hits	26	Shared Neighborhood Hits	14
SwissProt Accessions	P27105, Q14087, Q15609, Q5VX96, Q96FK4	Gene names	STOM, BND7, EPB72
Domain Architecture
Description	Erythrocyte band 7 integral membrane protein (Stomatin) (Protein 7.2b).

STML3_MOUSE
NC score	0.115274 (rank : 9)	θ value	0.0736092 (rank : 8)
Query Neighborhood Hits	91	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PE84, Q66JM3, Q8K4P4	Gene names	Stoml3, Sro
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 3 (Stomatin-related olfactory protein).

STML3_HUMAN
NC score	0.114103 (rank : 10)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	91	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TAV4, Q5JS35	Gene names	STOML3
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 3.

TAF3_HUMAN
NC score	0.104555 (rank : 11)	θ value	0.0252991 (rank : 5)
Query Neighborhood Hits	91	Target Neighborhood Hits	568	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

FLOT2_MOUSE
NC score	0.100622 (rank : 12)	θ value	1.38821 (rank : 31)
Query Neighborhood Hits	91	Target Neighborhood Hits	90	Shared Neighborhood Hits	21
SwissProt Accessions	Q60634, Q6NS75	Gene names	Flot2, Esa1, M17s1
Domain Architecture
Description	Flotillin-2 (Epidermal surface antigen) (ESA).

FLOT2_HUMAN
NC score	0.100194 (rank : 13)	θ value	1.38821 (rank : 30)
Query Neighborhood Hits	91	Target Neighborhood Hits	87	Shared Neighborhood Hits	19
SwissProt Accessions	Q14254	Gene names	FLOT2, ESA1, M17S1
Domain Architecture
Description	Flotillin-2 (Epidermal surface antigen) (ESA).

CAF1A_HUMAN
NC score	0.088412 (rank : 14)	θ value	0.0431538 (rank : 6)
Query Neighborhood Hits	91	Target Neighborhood Hits	750	Shared Neighborhood Hits	41
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

STOM_MOUSE
NC score	0.087410 (rank : 15)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	91	Target Neighborhood Hits	22	Shared Neighborhood Hits	13
SwissProt Accessions	P54116, Q60744, Q62455	Gene names	Stom, Epb7.2, Epb72
Domain Architecture
Description	Erythrocyte band 7 integral membrane protein (Stomatin) (Protein 7.2b).

CK5P3_MOUSE
NC score	0.086822 (rank : 16)	θ value	0.279714 (rank : 15)
Query Neighborhood Hits	91	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	Q99LM2, Q3UE41	Gene names	Cdk5rap3
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 3.

MED4_MOUSE
NC score	0.084591 (rank : 17)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	91	Target Neighborhood Hits	124	Shared Neighborhood Hits	10
SwissProt Accessions	Q9CQA5	Gene names	Med4, Vdrip
Domain Architecture	No domain graphic available
Description	Mediator complex subunit 4 (Mediator of RNA polymerase II transcription subunit 4).

PHB2_HUMAN
NC score	0.074948 (rank : 18)	θ value	0.813845 (rank : 22)
Query Neighborhood Hits	91	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q99623, Q7KYU3, Q92978	Gene names	PHB2, BAP, REA
Domain Architecture	No domain graphic available
Description	Prohibitin-2 (B-cell receptor-associated protein BAP37) (Repressor of estrogen receptor activity) (D-prohibitin).

PHB2_MOUSE
NC score	0.074948 (rank : 19)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	91	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	O35129, O89075, Q61336	Gene names	Phb2, Bap, Bcap37, Rea
Domain Architecture	No domain graphic available
Description	Prohibitin-2 (B-cell receptor-associated protein BAP37) (Repressor of estrogen receptor activity).

JIP3_HUMAN
NC score	0.073203 (rank : 20)	θ value	0.125558 (rank : 10)
Query Neighborhood Hits	91	Target Neighborhood Hits	1039	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UPT6, Q96RY4, Q9H4I4, Q9H7P1, Q9NUG0	Gene names	MAPK8IP3, JIP3, KIAA1066
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3).

CK5P3_HUMAN
NC score	0.071185 (rank : 21)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	91	Target Neighborhood Hits	38	Shared Neighborhood Hits	10
SwissProt Accessions	Q96JB5, Q53FA2, Q9H3F8, Q9H8G0, Q9HBR9	Gene names	CDK5RAP3, IC53
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 3 (CDK5 activator-binding protein C53) (HSF-27 protein).

STML1_MOUSE
NC score	0.068946 (rank : 22)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	91	Target Neighborhood Hits	29	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CI66, Q8BLA3	Gene names	Stoml1
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 1 (SLP-1).

MAP9_MOUSE
NC score	0.068848 (rank : 23)	θ value	0.279714 (rank : 16)
Query Neighborhood Hits	91	Target Neighborhood Hits	529	Shared Neighborhood Hits	22
SwissProt Accessions	Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7	Gene names	Map9, Asap
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

FLOT1_MOUSE
NC score	0.067475 (rank : 24)	θ value	3.0926 (rank : 48)
Query Neighborhood Hits	91	Target Neighborhood Hits	128	Shared Neighborhood Hits	22
SwissProt Accessions	O08917	Gene names	Flot1
Domain Architecture
Description	Flotillin-1.

STML1_HUMAN
NC score	0.066828 (rank : 25)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	91	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBI4, O95675, Q6FGL8, Q8WYI7, Q9UMB9, Q9UMC0, Q9Y6H9	Gene names	STOML1, SLP1, UNC24
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 1 (SLP-1) (Stomatin-related protein) (STORP) (EPB72-like 1) (UNC24 homolog).

MAP9_HUMAN
NC score	0.065070 (rank : 26)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	91	Target Neighborhood Hits	518	Shared Neighborhood Hits	26
SwissProt Accessions	Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6	Gene names	MAP9, ASAP
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 9 (Aster-associated protein).

TAF3_MOUSE
NC score	0.057163 (rank : 27)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	91	Target Neighborhood Hits	463	Shared Neighborhood Hits	22
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

PHLB2_HUMAN
NC score	0.056788 (rank : 28)	θ value	0.62314 (rank : 20)
Query Neighborhood Hits	91	Target Neighborhood Hits	964	Shared Neighborhood Hits	53
SwissProt Accessions	Q86SQ0, Q59EA8, Q68CY3, Q6NT98, Q8N8U8, Q8NAB1, Q8NCU5	Gene names	PHLDB2, LL5B
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

STML2_HUMAN
NC score	0.055102 (rank : 29)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	91	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UJZ1, O60376, Q53G29, Q96FY2, Q9P042	Gene names	STOML2, SLP2
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 2 (SLP-2) (EPB72-like 2).

STML2_MOUSE
NC score	0.054899 (rank : 30)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	91	Target Neighborhood Hits	23	Shared Neighborhood Hits	10
SwissProt Accessions	Q99JB2, Q9DCG8	Gene names	Stoml2, Slp2
Domain Architecture	No domain graphic available
Description	Stomatin-like protein 2 (SLP-2).

PEPL_HUMAN
NC score	0.052296 (rank : 31)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	91	Target Neighborhood Hits	1141	Shared Neighborhood Hits	52
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

PHLB2_MOUSE
NC score	0.051771 (rank : 32)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	91	Target Neighborhood Hits	1016	Shared Neighborhood Hits	56
SwissProt Accessions	Q8K1N2, Q3TNI3, Q80Y16, Q8BKV3	Gene names	Phldb2, Ll5b
Domain Architecture	No domain graphic available
Description	Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).

CEP55_MOUSE
NC score	0.051216 (rank : 33)	θ value	0.62314 (rank : 19)
Query Neighborhood Hits	91	Target Neighborhood Hits	693	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BT07, Q8C2J0, Q8K2I8, Q8R2Y4, Q9DBZ8	Gene names	Cep55
Domain Architecture	No domain graphic available
Description	Centrosome protein 55.

TUFT1_HUMAN
NC score	0.048116 (rank : 34)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	91	Target Neighborhood Hits	686	Shared Neighborhood Hits	37
SwissProt Accessions	Q9NNX1, Q5T384, Q5T385, Q9BU28, Q9H5L1	Gene names	TUFT1
Domain Architecture	No domain graphic available
Description	Tuftelin.

JIP3_MOUSE
NC score	0.047235 (rank : 35)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	91	Target Neighborhood Hits	759	Shared Neighborhood Hits	44
SwissProt Accessions	Q9ESN9, Q99KU7, Q9EQD8, Q9ESN7, Q9ESN8, Q9ESP0, Q9JLH2, Q9JLH3, Q9R0U7	Gene names	Mapk8ip3, Jip3, Jsap1, Syd2
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 3 (JNK-interacting protein 3) (JIP-3) (JNK MAP kinase scaffold protein 3) (Mitogen- activated protein kinase 8-interacting protein 3) (JNK/SAPK-associated protein 1) (JSAP1) (Sunday driver 2).

CE290_HUMAN
NC score	0.047110 (rank : 36)	θ value	1.38821 (rank : 29)
Query Neighborhood Hits	91	Target Neighborhood Hits	1553	Shared Neighborhood Hits	63
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

MVP_HUMAN
NC score	0.046949 (rank : 37)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	91	Target Neighborhood Hits	85	Shared Neighborhood Hits	12
SwissProt Accessions	Q14764, Q96BG4, Q9BPW6, Q9BQT1, Q9UBD1	Gene names	MVP, LRP
Domain Architecture
Description	Major vault protein (MVP) (Lung resistance-related protein).

SYCP1_HUMAN
NC score	0.045881 (rank : 38)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	91	Target Neighborhood Hits	1313	Shared Neighborhood Hits	59
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

VDP_HUMAN
NC score	0.045193 (rank : 39)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	91	Target Neighborhood Hits	645	Shared Neighborhood Hits	34
SwissProt Accessions	O60763	Gene names	VDP
Domain Architecture
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

CCD55_HUMAN
NC score	0.044746 (rank : 40)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	91	Target Neighborhood Hits	513	Shared Neighborhood Hits	30
SwissProt Accessions	Q9H0G5, Q6FI71	Gene names	CCDC55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

TPX2_HUMAN
NC score	0.044578 (rank : 41)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	91	Target Neighborhood Hits	150	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULW0, Q9H1R4, Q9NRA3, Q9UFN9, Q9UL00, Q9Y2M1	Gene names	TPX2, C20orf1, C20orf2, DIL2, HCA519
Domain Architecture	No domain graphic available
Description	Targeting protein for Xklp2 (Restricted expression proliferation- associated protein 100) (p100) (Differentially expressed in cancerous and noncancerous lung cells 2) (DIL-2) (Protein FLS353) (Hepatocellular carcinoma-associated antigen 519).

NOL8_MOUSE
NC score	0.043018 (rank : 42)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	91	Target Neighborhood Hits	210	Shared Neighborhood Hits	11
SwissProt Accessions	Q3UHX0, Q504M4, Q8CDJ7, Q9CUR0	Gene names	Nol8
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8.

OPTN_MOUSE
NC score	0.042840 (rank : 43)	θ value	4.03905 (rank : 58)
Query Neighborhood Hits	91	Target Neighborhood Hits	1120	Shared Neighborhood Hits	53
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

MVP_MOUSE
NC score	0.042552 (rank : 44)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	91	Target Neighborhood Hits	98	Shared Neighborhood Hits	17
SwissProt Accessions	Q9EQK5	Gene names	Mvp
Domain Architecture
Description	Major vault protein (MVP).

PEPL_MOUSE
NC score	0.042377 (rank : 45)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	91	Target Neighborhood Hits	1105	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

SYCP1_MOUSE
NC score	0.041550 (rank : 46)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	91	Target Neighborhood Hits	1456	Shared Neighborhood Hits	60
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CENPH_MOUSE
NC score	0.040915 (rank : 47)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	91	Target Neighborhood Hits	195	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYM8, Q8R3K9, Q9D079, Q9D0N1	Gene names	Cenph, Enp
Domain Architecture	No domain graphic available
Description	Centromere protein H (CENP-H).

GOGA4_MOUSE
NC score	0.040394 (rank : 48)	θ value	4.03905 (rank : 55)
Query Neighborhood Hits	91	Target Neighborhood Hits	1939	Shared Neighborhood Hits	75
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

SDS3_MOUSE
NC score	0.040072 (rank : 49)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	91	Target Neighborhood Hits	248	Shared Neighborhood Hits	27
SwissProt Accessions	Q8BR65, Q3UC92, Q6P6K1, Q7TNT0, Q8BRR7, Q8K5B4	Gene names	Suds3, Sds3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

PLEC1_HUMAN
NC score	0.039533 (rank : 50)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	91	Target Neighborhood Hits	1326	Shared Neighborhood Hits	55
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

PIBF1_HUMAN
NC score	0.039061 (rank : 51)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	91	Target Neighborhood Hits	1041	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

AZI1_HUMAN
NC score	0.038928 (rank : 52)	θ value	3.0926 (rank : 47)
Query Neighborhood Hits	91	Target Neighborhood Hits	1000	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

MYH10_MOUSE
NC score	0.037938 (rank : 53)	θ value	1.38821 (rank : 32)
Query Neighborhood Hits	91	Target Neighborhood Hits	1612	Shared Neighborhood Hits	62
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_HUMAN
NC score	0.037556 (rank : 54)	θ value	1.81305 (rank : 38)
Query Neighborhood Hits	91	Target Neighborhood Hits	1620	Shared Neighborhood Hits	63
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

SRGP1_HUMAN
NC score	0.037529 (rank : 55)	θ value	0.125558 (rank : 13)
Query Neighborhood Hits	91	Target Neighborhood Hits	390	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

STIM1_HUMAN
NC score	0.036703 (rank : 56)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	91	Target Neighborhood Hits	665	Shared Neighborhood Hits	48
SwissProt Accessions	Q13586	Gene names	STIM1, GOK
Domain Architecture
Description	Stromal interaction molecule 1 precursor.

SDS3_HUMAN
NC score	0.035796 (rank : 57)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	91	Target Neighborhood Hits	257	Shared Neighborhood Hits	27
SwissProt Accessions	Q9H7L9, Q8N6H0, Q9H8D2	Gene names	SUDS3, SDS3
Domain Architecture	No domain graphic available
Description	Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog).

MACF1_MOUSE
NC score	0.035492 (rank : 58)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	91	Target Neighborhood Hits	1313	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

GOGB1_HUMAN
NC score	0.035425 (rank : 59)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	91	Target Neighborhood Hits	2297	Shared Neighborhood Hits	70
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MYO6_HUMAN
NC score	0.035425 (rank : 60)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	91	Target Neighborhood Hits	727	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

MYH14_MOUSE
NC score	0.035222 (rank : 61)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	91	Target Neighborhood Hits	1225	Shared Neighborhood Hits	52
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

GBP2_MOUSE
NC score	0.034321 (rank : 62)	θ value	0.163984 (rank : 14)
Query Neighborhood Hits	91	Target Neighborhood Hits	323	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Z0E6, Q8CIC6, Q921N2, Q9R1I0	Gene names	Gbp2
Domain Architecture
Description	Interferon-induced guanylate-binding protein 2 (GTP-binding protein 2) (Guanine nucleotide-binding protein 2) (GBP-2) (mGBP2) (mGBP-2).

MYH13_HUMAN
NC score	0.034180 (rank : 63)	θ value	1.38821 (rank : 33)
Query Neighborhood Hits	91	Target Neighborhood Hits	1504	Shared Neighborhood Hits	50
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

KMHN1_HUMAN
NC score	0.034108 (rank : 64)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	91	Target Neighborhood Hits	950	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

MERL_MOUSE
NC score	0.033483 (rank : 65)	θ value	1.81305 (rank : 37)
Query Neighborhood Hits	91	Target Neighborhood Hits	524	Shared Neighborhood Hits	43
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

MERL_HUMAN
NC score	0.033058 (rank : 66)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	91	Target Neighborhood Hits	532	Shared Neighborhood Hits	42
SwissProt Accessions	P35240, O95683, Q8WUJ2, Q969N0, Q969Q3, Q96T30, Q96T31, Q96T32, Q96T33, Q9BTW3, Q9UNG9, Q9UNH3, Q9UNH4	Gene names	NF2, SCH
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin) (Schwannomerlin).

CENPE_HUMAN
NC score	0.032612 (rank : 67)	θ value	2.36792 (rank : 42)
Query Neighborhood Hits	91	Target Neighborhood Hits	2060	Shared Neighborhood Hits	67
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

TRI35_HUMAN
NC score	0.032359 (rank : 68)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	91	Target Neighborhood Hits	382	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UPQ4, Q86XQ0, Q8WVA4	Gene names	TRIM35, HLS5, KIAA1098
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Hemopoietic lineage switch protein 5).

MYH14_HUMAN
NC score	0.031811 (rank : 69)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	91	Target Neighborhood Hits	995	Shared Neighborhood Hits	42
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

CALD1_HUMAN
NC score	0.030584 (rank : 70)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	91	Target Neighborhood Hits	959	Shared Neighborhood Hits	44
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

TPM3_HUMAN
NC score	0.029623 (rank : 71)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	91	Target Neighborhood Hits	689	Shared Neighborhood Hits	33
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

BRE1A_MOUSE
NC score	0.029096 (rank : 72)	θ value	4.03905 (rank : 54)
Query Neighborhood Hits	91	Target Neighborhood Hits	1025	Shared Neighborhood Hits	44
SwissProt Accessions	Q5DTM8, Q3UT10, Q3V350, Q7TT11, Q8BKA8, Q8BKN8, Q8BUF7, Q8BVU4	Gene names	Rnf20, Bre1a, Kiaa4116
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1A (EC 6.3.2.-) (BRE1-A) (RING finger protein 20).

TPM3_MOUSE
NC score	0.028941 (rank : 73)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	91	Target Neighborhood Hits	676	Shared Neighborhood Hits	34
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

MYO6_MOUSE
NC score	0.028748 (rank : 74)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	91	Target Neighborhood Hits	586	Shared Neighborhood Hits	39
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

NOL8_HUMAN
NC score	0.028406 (rank : 75)	θ value	4.03905 (rank : 57)
Query Neighborhood Hits	91	Target Neighborhood Hits	297	Shared Neighborhood Hits	10
SwissProt Accessions	Q76FK4, Q5TCC7, Q5TCC8, Q5TCD3, Q5TCD5, Q5TCD6, Q5TCD7, Q76D35, Q7L3E2, Q9H586, Q9H795, Q9H7W7, Q9H9J6, Q9NWA4, Q9NWM4	Gene names	NOL8, NOP132
Domain Architecture	No domain graphic available
Description	Nucleolar protein 8 (Nucleolar protein Nop132).

OTU6B_MOUSE
NC score	0.028394 (rank : 76)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	91	Target Neighborhood Hits	202	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K2H2	Gene names	Otud6b
Domain Architecture	No domain graphic available
Description	OTU domain-containing protein 6B.

TRI35_MOUSE
NC score	0.028351 (rank : 77)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	91	Target Neighborhood Hits	465	Shared Neighborhood Hits	33
SwissProt Accessions	Q8C006, Q6ZPY0, Q7TQL7, Q810V7, Q8BVY9, Q8VID4, Q9CW74, Q9D208	Gene names	Trim35, Hls5, Kiaa1098, Mair
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 35 (Macrophage-derived apoptosis- inducing RBCC protein) (Protein MAIR) (Protein Nc8) (Hemopoietic lineage switch protein 5).

TRDN_HUMAN
NC score	0.028279 (rank : 78)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	91	Target Neighborhood Hits	542	Shared Neighborhood Hits	22
SwissProt Accessions	Q13061	Gene names	TRDN
Domain Architecture
Description	Triadin.

ACINU_HUMAN
NC score	0.027806 (rank : 79)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	91	Target Neighborhood Hits	828	Shared Neighborhood Hits	38
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

MOES_MOUSE
NC score	0.026608 (rank : 80)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	91	Target Neighborhood Hits	923	Shared Neighborhood Hits	47
SwissProt Accessions	P26041, Q3UL28, Q8BSN4	Gene names	Msn
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

HGS_MOUSE
NC score	0.026323 (rank : 81)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	91	Target Neighborhood Hits	589	Shared Neighborhood Hits	13
SwissProt Accessions	Q99LI8, Q61691, Q8BQW3	Gene names	Hgs, Hrs
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate.

CCD55_MOUSE
NC score	0.025909 (rank : 82)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	91	Target Neighborhood Hits	519	Shared Neighborhood Hits	19
SwissProt Accessions	Q5NCR9	Gene names	Ccdc55
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 55.

UBP8_HUMAN
NC score	0.024937 (rank : 83)	θ value	1.06291 (rank : 28)
Query Neighborhood Hits	91	Target Neighborhood Hits	751	Shared Neighborhood Hits	38
SwissProt Accessions	P40818, Q7Z3U2, Q86VA0, Q8IWI7	Gene names	USP8, KIAA0055, UBPY
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.1.2.15) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8) (Deubiquitinating enzyme 8) (hUBPy).

TBC14_HUMAN
NC score	0.023639 (rank : 84)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	91	Target Neighborhood Hits	124	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P2M4, Q8IW15	Gene names	TBC1D14, KIAA1322
Domain Architecture
Description	TBC1 domain family member 14.

TBC12_HUMAN
NC score	0.022213 (rank : 85)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	91	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	O60347, Q5VYA6, Q8WX26, Q8WX59, Q9UG83	Gene names	TBC1D12, KIAA0608
Domain Architecture
Description	TBC1 domain family member 12.

LRC59_HUMAN
NC score	0.022115 (rank : 86)	θ value	4.03905 (rank : 56)
Query Neighborhood Hits	91	Target Neighborhood Hits	398	Shared Neighborhood Hits	12
SwissProt Accessions	Q96AG4, Q9P189	Gene names	LRRC59
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 59.

TEKT1_MOUSE
NC score	0.022031 (rank : 87)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	91	Target Neighborhood Hits	399	Shared Neighborhood Hits	26
SwissProt Accessions	Q9DAJ2	Gene names	Tekt1
Domain Architecture
Description	Tektin-1.

LRC59_MOUSE
NC score	0.019782 (rank : 88)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	91	Target Neighborhood Hits	415	Shared Neighborhood Hits	16
SwissProt Accessions	Q922Q8, Q3TJ35, Q3TLC7, Q3TWT9, Q3TX86	Gene names	Lrrc59
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 59.

K1C10_HUMAN
NC score	0.016749 (rank : 89)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	91	Target Neighborhood Hits	526	Shared Neighborhood Hits	30
SwissProt Accessions	P13645, Q14664, Q8N175	Gene names	KRT10
Domain Architecture
Description	Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10).

TRIM1_HUMAN
NC score	0.016240 (rank : 90)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	91	Target Neighborhood Hits	345	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UJV3, Q5JYF5, Q8WWK1, Q9UJR9	Gene names	MID2, FXY2, RNF60, TRIM1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1) (Midin-2) (RING finger protein 60).

TRIM1_MOUSE
NC score	0.016104 (rank : 91)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	91	Target Neighborhood Hits	361	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QUS6	Gene names	Mid2, Fxy2, Trim1
Domain Architecture
Description	Midline-2 (Midline defect 2) (Tripartite motif-containing protein 1).

PABP4_HUMAN
NC score	0.016029 (rank : 92)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	91	Target Neighborhood Hits	268	Shared Neighborhood Hits	5
SwissProt Accessions	Q13310, Q6P0N3	Gene names	PABPC4, APP1, PABP4
Domain Architecture
Description	Polyadenylate-binding protein 4 (Poly(A)-binding protein 4) (PABP 4) (Inducible poly(A)-binding protein) (iPABP) (Activated-platelet protein 1) (APP-1).

BAZ2A_HUMAN
NC score	0.014941 (rank : 93)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	91	Target Neighborhood Hits	780	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UIF9, O00536, O15030, Q96H26	Gene names	BAZ2A, KIAA0314, TIP5
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2A (Transcription termination factor I-interacting protein 5) (TTF-I-interacting protein 5) (Tip5) (hWALp3).

JAD1A_HUMAN
NC score	0.010978 (rank : 94)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	91	Target Neighborhood Hits	328	Shared Neighborhood Hits	19
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).