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Network neighborhood for query Sequence : SUSD4_HUMAN

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SUSD4_HUMAN
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SUSD4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	88
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

SUSD4_MOUSE
θ value	0 (rank : 2)	NC score	0.989961 (rank : 2)
Query Neighborhood Hits	88	Target Neighborhood Hits	122	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

K0247_HUMAN
θ value	3.17815e-21 (rank : 3)	NC score	0.621870 (rank : 28)
Query Neighborhood Hits	88	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	Q92537	Gene names	KIAA0247
Domain Architecture	No domain graphic available
Description	Protein KIAA0247 precursor.

CSMD3_HUMAN
θ value	1.63225e-17 (rank : 4)	NC score	0.610235 (rank : 31)
Query Neighborhood Hits	88	Target Neighborhood Hits	199	Shared Neighborhood Hits	65
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

F13B_MOUSE
θ value	8.10077e-17 (rank : 5)	NC score	0.777630 (rank : 3)
Query Neighborhood Hits	88	Target Neighborhood Hits	93	Shared Neighborhood Hits	62
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

F13B_HUMAN
θ value	1.38178e-16 (rank : 6)	NC score	0.776007 (rank : 4)
Query Neighborhood Hits	88	Target Neighborhood Hits	84	Shared Neighborhood Hits	61
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

CSMD1_MOUSE
θ value	5.25075e-16 (rank : 7)	NC score	0.595324 (rank : 34)
Query Neighborhood Hits	88	Target Neighborhood Hits	193	Shared Neighborhood Hits	63
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CFAH_MOUSE
θ value	1.99529e-15 (rank : 8)	NC score	0.759200 (rank : 6)
Query Neighborhood Hits	88	Target Neighborhood Hits	112	Shared Neighborhood Hits	65
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

LYAM3_HUMAN
θ value	1.99529e-15 (rank : 9)	NC score	0.627353 (rank : 27)
Query Neighborhood Hits	88	Target Neighborhood Hits	378	Shared Neighborhood Hits	64
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

CSMD2_HUMAN
θ value	2.20605e-14 (rank : 10)	NC score	0.587213 (rank : 37)
Query Neighborhood Hits	88	Target Neighborhood Hits	188	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD1_HUMAN
θ value	6.41864e-14 (rank : 11)	NC score	0.594436 (rank : 35)
Query Neighborhood Hits	88	Target Neighborhood Hits	176	Shared Neighborhood Hits	64
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CR1_HUMAN
θ value	1.42992e-13 (rank : 12)	NC score	0.757635 (rank : 8)
Query Neighborhood Hits	88	Target Neighborhood Hits	108	Shared Neighborhood Hits	67
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

CFAH_HUMAN
θ value	2.43908e-13 (rank : 13)	NC score	0.748502 (rank : 13)
Query Neighborhood Hits	88	Target Neighborhood Hits	101	Shared Neighborhood Hits	65
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

CR2_MOUSE
θ value	2.43908e-13 (rank : 14)	NC score	0.754404 (rank : 11)
Query Neighborhood Hits	88	Target Neighborhood Hits	101	Shared Neighborhood Hits	64
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

LYAM2_HUMAN
θ value	9.26847e-13 (rank : 15)	NC score	0.597659 (rank : 33)
Query Neighborhood Hits	88	Target Neighborhood Hits	394	Shared Neighborhood Hits	65
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CR2_HUMAN
θ value	1.2105e-12 (rank : 16)	NC score	0.755082 (rank : 10)
Query Neighborhood Hits	88	Target Neighborhood Hits	89	Shared Neighborhood Hits	64
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

FHR5_HUMAN
θ value	2.0648e-12 (rank : 17)	NC score	0.732850 (rank : 15)
Query Neighborhood Hits	88	Target Neighborhood Hits	77	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

C4BP_MOUSE
θ value	3.52202e-12 (rank : 18)	NC score	0.763589 (rank : 5)
Query Neighborhood Hits	88	Target Neighborhood Hits	91	Shared Neighborhood Hits	65
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

LYAM3_MOUSE
θ value	3.52202e-12 (rank : 19)	NC score	0.610263 (rank : 30)
Query Neighborhood Hits	88	Target Neighborhood Hits	390	Shared Neighborhood Hits	65
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

CRRY_MOUSE
θ value	4.59992e-12 (rank : 20)	NC score	0.758943 (rank : 7)
Query Neighborhood Hits	88	Target Neighborhood Hits	84	Shared Neighborhood Hits	63
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

C4BP_HUMAN
θ value	7.84624e-12 (rank : 21)	NC score	0.757177 (rank : 9)
Query Neighborhood Hits	88	Target Neighborhood Hits	92	Shared Neighborhood Hits	64
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

FHR3_HUMAN
θ value	1.33837e-11 (rank : 22)	NC score	0.690184 (rank : 24)
Query Neighborhood Hits	88	Target Neighborhood Hits	74	Shared Neighborhood Hits	58
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

LYAM2_MOUSE
θ value	1.33837e-11 (rank : 23)	NC score	0.591137 (rank : 36)
Query Neighborhood Hits	88	Target Neighborhood Hits	420	Shared Neighborhood Hits	65
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

ZP3R_MOUSE
θ value	1.33837e-11 (rank : 24)	NC score	0.749580 (rank : 12)
Query Neighborhood Hits	88	Target Neighborhood Hits	81	Shared Neighborhood Hits	62
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

DAF1_MOUSE
θ value	3.89403e-11 (rank : 25)	NC score	0.713448 (rank : 20)
Query Neighborhood Hits	88	Target Neighborhood Hits	204	Shared Neighborhood Hits	63
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

FHR4_HUMAN
θ value	1.47974e-10 (rank : 26)	NC score	0.686213 (rank : 25)
Query Neighborhood Hits	88	Target Neighborhood Hits	75	Shared Neighborhood Hits	59
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

DAF2_MOUSE
θ value	9.59137e-10 (rank : 27)	NC score	0.721325 (rank : 19)
Query Neighborhood Hits	88	Target Neighborhood Hits	114	Shared Neighborhood Hits	63
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

MCP_HUMAN
θ value	2.79066e-09 (rank : 28)	NC score	0.727490 (rank : 16)
Query Neighborhood Hits	88	Target Neighborhood Hits	82	Shared Neighborhood Hits	61
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

FHR2_HUMAN
θ value	6.87365e-08 (rank : 29)	NC score	0.665697 (rank : 26)
Query Neighborhood Hits	88	Target Neighborhood Hits	63	Shared Neighborhood Hits	55
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

APOH_MOUSE
θ value	8.97725e-08 (rank : 30)	NC score	0.736256 (rank : 14)
Query Neighborhood Hits	88	Target Neighborhood Hits	74	Shared Neighborhood Hits	62
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

FHR1_HUMAN
θ value	1.17247e-07 (rank : 31)	NC score	0.701808 (rank : 22)
Query Neighborhood Hits	88	Target Neighborhood Hits	80	Shared Neighborhood Hits	60
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

DAF_HUMAN
θ value	1.99992e-07 (rank : 32)	NC score	0.722002 (rank : 18)
Query Neighborhood Hits	88	Target Neighborhood Hits	97	Shared Neighborhood Hits	64
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

APOH_HUMAN
θ value	5.81887e-07 (rank : 33)	NC score	0.725822 (rank : 17)
Query Neighborhood Hits	88	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

SEZ6L_HUMAN
θ value	5.81887e-07 (rank : 34)	NC score	0.570541 (rank : 38)
Query Neighborhood Hits	88	Target Neighborhood Hits	289	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

CO6_HUMAN
θ value	8.40245e-06 (rank : 35)	NC score	0.306314 (rank : 51)
Query Neighborhood Hits	88	Target Neighborhood Hits	331	Shared Neighborhood Hits	56
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

SRPX_HUMAN
θ value	3.19293e-05 (rank : 36)	NC score	0.602027 (rank : 32)
Query Neighborhood Hits	88	Target Neighborhood Hits	69	Shared Neighborhood Hits	57
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

SRPX_MOUSE
θ value	3.19293e-05 (rank : 37)	NC score	0.612856 (rank : 29)
Query Neighborhood Hits	88	Target Neighborhood Hits	75	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

PAP2_HUMAN
θ value	4.1701e-05 (rank : 38)	NC score	0.449588 (rank : 41)
Query Neighborhood Hits	88	Target Neighborhood Hits	106	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

MCP_MOUSE
θ value	5.44631e-05 (rank : 39)	NC score	0.695780 (rank : 23)
Query Neighborhood Hits	88	Target Neighborhood Hits	79	Shared Neighborhood Hits	61
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

CO2_HUMAN
θ value	0.000121331 (rank : 40)	NC score	0.381338 (rank : 44)
Query Neighborhood Hits	88	Target Neighborhood Hits	258	Shared Neighborhood Hits	60
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO2_MOUSE
θ value	0.000158464 (rank : 41)	NC score	0.324823 (rank : 48)
Query Neighborhood Hits	88	Target Neighborhood Hits	250	Shared Neighborhood Hits	60
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO7_HUMAN
θ value	0.000158464 (rank : 42)	NC score	0.340556 (rank : 47)
Query Neighborhood Hits	88	Target Neighborhood Hits	278	Shared Neighborhood Hits	48
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

PAPPA_MOUSE
θ value	0.00020696 (rank : 43)	NC score	0.471505 (rank : 40)
Query Neighborhood Hits	88	Target Neighborhood Hits	153	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

C4BB_HUMAN
θ value	0.000461057 (rank : 44)	NC score	0.704558 (rank : 21)
Query Neighborhood Hits	88	Target Neighborhood Hits	77	Shared Neighborhood Hits	61
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

PAPPA_HUMAN
θ value	0.00102713 (rank : 45)	NC score	0.477874 (rank : 39)
Query Neighborhood Hits	88	Target Neighborhood Hits	161	Shared Neighborhood Hits	54
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

CFAB_MOUSE
θ value	0.00298849 (rank : 46)	NC score	0.371384 (rank : 45)
Query Neighborhood Hits	88	Target Neighborhood Hits	262	Shared Neighborhood Hits	64
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

C1R_HUMAN
θ value	0.00390308 (rank : 47)	NC score	0.150441 (rank : 66)
Query Neighborhood Hits	88	Target Neighborhood Hits	364	Shared Neighborhood Hits	48
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

CFAB_HUMAN
θ value	0.00390308 (rank : 48)	NC score	0.369201 (rank : 46)
Query Neighborhood Hits	88	Target Neighborhood Hits	251	Shared Neighborhood Hits	64
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

C1RA_MOUSE
θ value	0.00869519 (rank : 49)	NC score	0.156588 (rank : 59)
Query Neighborhood Hits	88	Target Neighborhood Hits	379	Shared Neighborhood Hits	49
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

PERT_MOUSE
θ value	0.0252991 (rank : 50)	NC score	0.178410 (rank : 56)
Query Neighborhood Hits	88	Target Neighborhood Hits	221	Shared Neighborhood Hits	51
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

MASP1_HUMAN
θ value	0.0431538 (rank : 51)	NC score	0.153468 (rank : 64)
Query Neighborhood Hits	88	Target Neighborhood Hits	369	Shared Neighborhood Hits	56
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

C1RB_MOUSE
θ value	0.0563607 (rank : 52)	NC score	0.153001 (rank : 65)
Query Neighborhood Hits	88	Target Neighborhood Hits	380	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

GABR1_HUMAN
θ value	0.0736092 (rank : 53)	NC score	0.272506 (rank : 52)
Query Neighborhood Hits	88	Target Neighborhood Hits	142	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
θ value	0.0736092 (rank : 54)	NC score	0.271230 (rank : 53)
Query Neighborhood Hits	88	Target Neighborhood Hits	139	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

CS1B_MOUSE
θ value	0.0961366 (rank : 55)	NC score	0.155538 (rank : 60)
Query Neighborhood Hits	88	Target Neighborhood Hits	361	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CS1A_MOUSE
θ value	0.125558 (rank : 56)	NC score	0.155183 (rank : 62)
Query Neighborhood Hits	88	Target Neighborhood Hits	360	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

HPT_HUMAN
θ value	0.125558 (rank : 57)	NC score	0.088933 (rank : 84)
Query Neighborhood Hits	88	Target Neighborhood Hits	184	Shared Neighborhood Hits	29
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

MAVS_MOUSE
θ value	0.21417 (rank : 58)	NC score	0.049833 (rank : 124)
Query Neighborhood Hits	88	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

LYAM1_HUMAN
θ value	0.279714 (rank : 59)	NC score	0.402074 (rank : 42)
Query Neighborhood Hits	88	Target Neighborhood Hits	315	Shared Neighborhood Hits	53
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

CABL1_HUMAN
θ value	0.62314 (rank : 60)	NC score	0.045168 (rank : 125)
Query Neighborhood Hits	88	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDN4, Q8N3Y8, Q8NA22, Q9BTG1	Gene names	CABLES1, CABLES
Domain Architecture	No domain graphic available
Description	CDK5 and ABL1 enzyme substrate 1 (Interactor with CDK3 1) (Ik3-1).

GLSK_HUMAN
θ value	0.813845 (rank : 61)	NC score	0.019109 (rank : 132)
Query Neighborhood Hits	88	Target Neighborhood Hits	204	Shared Neighborhood Hits	2
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

CB017_HUMAN
θ value	1.38821 (rank : 62)	NC score	0.052209 (rank : 121)
Query Neighborhood Hits	88	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NC44, Q6P1P5, Q9H0K7	Gene names	C2orf17
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf17.

ZN484_HUMAN
θ value	1.38821 (rank : 63)	NC score	-0.003023 (rank : 145)
Query Neighborhood Hits	88	Target Neighborhood Hits	766	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JVG2	Gene names	ZNF484
Domain Architecture	No domain graphic available
Description	Zinc finger protein 484.

LYAM1_MOUSE
θ value	1.81305 (rank : 64)	NC score	0.390249 (rank : 43)
Query Neighborhood Hits	88	Target Neighborhood Hits	332	Shared Neighborhood Hits	54
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

DMP1_HUMAN
θ value	2.36792 (rank : 65)	NC score	0.023846 (rank : 129)
Query Neighborhood Hits	88	Target Neighborhood Hits	491	Shared Neighborhood Hits	4
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DPP9_HUMAN
θ value	2.36792 (rank : 66)	NC score	0.019500 (rank : 131)
Query Neighborhood Hits	88	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q86TI2, Q6AI37, Q6UAL0, Q6ZMT2, Q6ZNJ5, Q8N2J7, Q8N3F5, Q8WXD8, Q96NT8, Q9BVR3	Gene names	DPP9, DPRP2
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9) (Dipeptidyl peptidase IV-related protein 2) (DPRP-2).

DPP9_MOUSE
θ value	2.36792 (rank : 67)	NC score	0.019522 (rank : 130)
Query Neighborhood Hits	88	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BVG4, Q6KAM9, Q8BWT9	Gene names	Dpp9
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9).

FBLN2_MOUSE
θ value	2.36792 (rank : 68)	NC score	0.027560 (rank : 127)
Query Neighborhood Hits	88	Target Neighborhood Hits	505	Shared Neighborhood Hits	25
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

SUSD3_MOUSE
θ value	2.36792 (rank : 69)	NC score	0.270398 (rank : 54)
Query Neighborhood Hits	88	Target Neighborhood Hits	39	Shared Neighborhood Hits	35
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

FOXC1_MOUSE
θ value	3.0926 (rank : 70)	NC score	0.007851 (rank : 138)
Query Neighborhood Hits	88	Target Neighborhood Hits	218	Shared Neighborhood Hits	6
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

MAP1A_HUMAN
θ value	3.0926 (rank : 71)	NC score	0.009256 (rank : 136)
Query Neighborhood Hits	88	Target Neighborhood Hits	1626	Shared Neighborhood Hits	8
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

RBM10_HUMAN
θ value	3.0926 (rank : 72)	NC score	0.013210 (rank : 134)
Query Neighborhood Hits	88	Target Neighborhood Hits	204	Shared Neighborhood Hits	2
SwissProt Accessions	P98175, Q14136	Gene names	RBM10, DXS8237E, KIAA0122
Domain Architecture
Description	RNA-binding protein 10 (RNA-binding motif protein 10).

SUSD2_MOUSE
θ value	3.0926 (rank : 73)	NC score	0.324745 (rank : 49)
Query Neighborhood Hits	88	Target Neighborhood Hits	104	Shared Neighborhood Hits	58
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

ZBT16_HUMAN
θ value	3.0926 (rank : 74)	NC score	-0.001665 (rank : 144)
Query Neighborhood Hits	88	Target Neighborhood Hits	1010	Shared Neighborhood Hits	7
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

CDX4_MOUSE
θ value	4.03905 (rank : 75)	NC score	0.002792 (rank : 143)
Query Neighborhood Hits	88	Target Neighborhood Hits	378	Shared Neighborhood Hits	4
SwissProt Accessions	Q07424	Gene names	Cdx4, Cdx-4
Domain Architecture
Description	Homeobox protein CDX-4 (Caudal-type homeobox protein 4).

PGCB_MOUSE
θ value	4.03905 (rank : 76)	NC score	0.077945 (rank : 97)
Query Neighborhood Hits	88	Target Neighborhood Hits	459	Shared Neighborhood Hits	43
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

CDSN_MOUSE
θ value	5.27518 (rank : 77)	NC score	0.015078 (rank : 133)
Query Neighborhood Hits	88	Target Neighborhood Hits	131	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TPC1	Gene names	Cdsn
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor.

ITIH4_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.009028 (rank : 137)
Query Neighborhood Hits	88	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q14624, Q15135, Q9P190, Q9UQ54	Gene names	ITIH4, IHRP, ITIHL1, PK120
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H4 precursor (ITI heavy chain H4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (PK-120) (GP120) [Contains: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha- trypsin inhibitor heavy chain H4].

LRC19_MOUSE
θ value	6.88961 (rank : 79)	NC score	0.005631 (rank : 139)
Query Neighborhood Hits	88	Target Neighborhood Hits	238	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BZT5, Q6P8J1	Gene names	Lrrc19
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 19 precursor.

SMAD5_MOUSE
θ value	6.88961 (rank : 80)	NC score	0.011029 (rank : 135)
Query Neighborhood Hits	88	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	P97454, P70341, Q810K0	Gene names	Smad5, Madh5, Msmad5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (mSmad5) (Dwarfin-C) (Dwf-C).

SRRM2_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.004665 (rank : 141)
Query Neighborhood Hits	88	Target Neighborhood Hits	1470	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

CSPG3_MOUSE
θ value	8.99809 (rank : 82)	NC score	0.101368 (rank : 76)
Query Neighborhood Hits	88	Target Neighborhood Hits	657	Shared Neighborhood Hits	48
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

FGD5_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.003228 (rank : 142)
Query Neighborhood Hits	88	Target Neighborhood Hits	235	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

PERT_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.147843 (rank : 67)
Query Neighborhood Hits	88	Target Neighborhood Hits	221	Shared Neighborhood Hits	50
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

POLS2_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.024477 (rank : 128)
Query Neighborhood Hits	88	Target Neighborhood Hits	188	Shared Neighborhood Hits	13
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

SUSD2_HUMAN
θ value	8.99809 (rank : 86)	NC score	0.317986 (rank : 50)
Query Neighborhood Hits	88	Target Neighborhood Hits	99	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

UBQL1_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.004954 (rank : 140)
Query Neighborhood Hits	88	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R317, Q80V10, Q8C7T4, Q8C835, Q8K141, Q91VI8, Q9D0Z0, Q9QZM1	Gene names	Ubqln1, Plic1
Domain Architecture
Description	Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1).

WFD13_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.033927 (rank : 126)
Query Neighborhood Hits	88	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IUB5, Q5TEU7, Q8WWK7	Gene names	WFDC13, C20orf138, WAP13
Domain Architecture	No domain graphic available
Description	Protein WFDC13 precursor.

ATRN_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.055568 (rank : 118)
Query Neighborhood Hits	88	Target Neighborhood Hits	525	Shared Neighborhood Hits	14
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.053681 (rank : 120)
Query Neighborhood Hits	88	Target Neighborhood Hits	519	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

BMP1_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.102228 (rank : 74)
Query Neighborhood Hits	88	Target Neighborhood Hits	233	Shared Neighborhood Hits	17
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.102647 (rank : 73)
Query Neighborhood Hits	88	Target Neighborhood Hits	236	Shared Neighborhood Hits	17
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

C1S_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.158852 (rank : 58)
Query Neighborhood Hits	88	Target Neighborhood Hits	359	Shared Neighborhood Hits	53
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CSPG2_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.083812 (rank : 90)
Query Neighborhood Hits	88	Target Neighborhood Hits	681	Shared Neighborhood Hits	42
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.084128 (rank : 88)
Query Neighborhood Hits	88	Target Neighborhood Hits	711	Shared Neighborhood Hits	42
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.093120 (rank : 79)
Query Neighborhood Hits	88	Target Neighborhood Hits	676	Shared Neighborhood Hits	49
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CUBN_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.088745 (rank : 85)
Query Neighborhood Hits	88	Target Neighborhood Hits	482	Shared Neighborhood Hits	24
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.080499 (rank : 93)
Query Neighborhood Hits	88	Target Neighborhood Hits	477	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CUZD1_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.080722 (rank : 92)
Query Neighborhood Hits	88	Target Neighborhood Hits	89	Shared Neighborhood Hits	11
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUZD1_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.075307 (rank : 104)
Query Neighborhood Hits	88	Target Neighborhood Hits	91	Shared Neighborhood Hits	11
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

DCBD1_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.050887 (rank : 123)
Query Neighborhood Hits	88	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD1_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.066220 (rank : 114)
Query Neighborhood Hits	88	Target Neighborhood Hits	89	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.060320 (rank : 115)
Query Neighborhood Hits	88	Target Neighborhood Hits	118	Shared Neighborhood Hits	11
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.054721 (rank : 119)
Query Neighborhood Hits	88	Target Neighborhood Hits	113	Shared Neighborhood Hits	11
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DMBT1_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.059726 (rank : 116)
Query Neighborhood Hits	88	Target Neighborhood Hits	152	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DMBT1_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.073093 (rank : 109)
Query Neighborhood Hits	88	Target Neighborhood Hits	134	Shared Neighborhood Hits	11
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

GP126_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.051049 (rank : 122)
Query Neighborhood Hits	88	Target Neighborhood Hits	187	Shared Neighborhood Hits	11
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

IL2RA_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.101777 (rank : 75)
Query Neighborhood Hits	88	Target Neighborhood Hits	32	Shared Neighborhood Hits	18
SwissProt Accessions	P01589	Gene names	IL2RA
Domain Architecture
Description	Interleukin-2 receptor alpha chain precursor (IL-2 receptor alpha subunit) (IL-2-RA) (IL2-RA) (p55) (TAC antigen) (CD25 antigen).

KREM1_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.075535 (rank : 103)
Query Neighborhood Hits	88	Target Neighborhood Hits	90	Shared Neighborhood Hits	11
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM1_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.074169 (rank : 107)
Query Neighborhood Hits	88	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM2_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.074336 (rank : 106)
Query Neighborhood Hits	88	Target Neighborhood Hits	93	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KREM2_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.069116 (rank : 112)
Query Neighborhood Hits	88	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

LRP12_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.078699 (rank : 95)
Query Neighborhood Hits	88	Target Neighborhood Hits	205	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.078375 (rank : 96)
Query Neighborhood Hits	88	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP3_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.055642 (rank : 117)
Query Neighborhood Hits	88	Target Neighborhood Hits	280	Shared Neighborhood Hits	13
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

MASP1_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.144586 (rank : 68)
Query Neighborhood Hits	88	Target Neighborhood Hits	364	Shared Neighborhood Hits	52
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MASP2_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.155257 (rank : 61)
Query Neighborhood Hits	88	Target Neighborhood Hits	364	Shared Neighborhood Hits	55
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.175191 (rank : 57)
Query Neighborhood Hits	88	Target Neighborhood Hits	382	Shared Neighborhood Hits	59
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MFRP_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.089664 (rank : 83)
Query Neighborhood Hits	88	Target Neighborhood Hits	165	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.092077 (rank : 80)
Query Neighborhood Hits	88	Target Neighborhood Hits	166	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NETO1_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.077270 (rank : 100)
Query Neighborhood Hits	88	Target Neighborhood Hits	110	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.076650 (rank : 102)
Query Neighborhood Hits	88	Target Neighborhood Hits	109	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.073896 (rank : 108)
Query Neighborhood Hits	88	Target Neighborhood Hits	109	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.072921 (rank : 110)
Query Neighborhood Hits	88	Target Neighborhood Hits	113	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NRP1_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.068835 (rank : 113)
Query Neighborhood Hits	88	Target Neighborhood Hits	119	Shared Neighborhood Hits	11
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.069852 (rank : 111)
Query Neighborhood Hits	88	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.076929 (rank : 101)
Query Neighborhood Hits	88	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.077924 (rank : 98)
Query Neighborhood Hits	88	Target Neighborhood Hits	113	Shared Neighborhood Hits	11
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

PCOC1_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.100072 (rank : 77)
Query Neighborhood Hits	88	Target Neighborhood Hits	146	Shared Neighborhood Hits	12
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.099197 (rank : 78)
Query Neighborhood Hits	88	Target Neighborhood Hits	100	Shared Neighborhood Hits	11
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.092020 (rank : 81)
Query Neighborhood Hits	88	Target Neighborhood Hits	73	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.089912 (rank : 82)
Query Neighborhood Hits	88	Target Neighborhood Hits	73	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PDGFD_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.077631 (rank : 99)
Query Neighborhood Hits	88	Target Neighborhood Hits	74	Shared Neighborhood Hits	11
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

PDGFD_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.074406 (rank : 105)
Query Neighborhood Hits	88	Target Neighborhood Hits	72	Shared Neighborhood Hits	10
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

PGCA_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.080493 (rank : 94)
Query Neighborhood Hits	88	Target Neighborhood Hits	821	Shared Neighborhood Hits	47
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PGCA_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.086730 (rank : 86)
Query Neighborhood Hits	88	Target Neighborhood Hits	643	Shared Neighborhood Hits	44
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PGCB_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.086660 (rank : 87)
Query Neighborhood Hits	88	Target Neighborhood Hits	478	Shared Neighborhood Hits	43
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

SUSD1_HUMAN
θ value	θ > 10 (rank : 138)	NC score	0.202360 (rank : 55)
Query Neighborhood Hits	88	Target Neighborhood Hits	285	Shared Neighborhood Hits	51
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

SUSD3_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.153779 (rank : 63)
Query Neighborhood Hits	88	Target Neighborhood Hits	32	Shared Neighborhood Hits	27
SwissProt Accessions	Q96L08, Q49AA6, Q6UXV7	Gene names	SUSD3, UNQ9387/PRO34275
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

TLL1_HUMAN
θ value	θ > 10 (rank : 140)	NC score	0.102943 (rank : 71)
Query Neighborhood Hits	88	Target Neighborhood Hits	236	Shared Neighborhood Hits	17
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.104898 (rank : 70)
Query Neighborhood Hits	88	Target Neighborhood Hits	237	Shared Neighborhood Hits	18
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.102689 (rank : 72)
Query Neighborhood Hits	88	Target Neighborhood Hits	241	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.105553 (rank : 69)
Query Neighborhood Hits	88	Target Neighborhood Hits	240	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TSG6_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.082646 (rank : 91)
Query Neighborhood Hits	88	Target Neighborhood Hits	91	Shared Neighborhood Hits	13
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 145)	NC score	0.083893 (rank : 89)
Query Neighborhood Hits	88	Target Neighborhood Hits	91	Shared Neighborhood Hits	13
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

Hits sorted by NC score

SUSD4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	88	Target Neighborhood Hits	88	Shared Neighborhood Hits	88
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

SUSD4_MOUSE
NC score	0.989961 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	88	Target Neighborhood Hits	122	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

F13B_MOUSE
NC score	0.777630 (rank : 3)	θ value	8.10077e-17 (rank : 5)
Query Neighborhood Hits	88	Target Neighborhood Hits	93	Shared Neighborhood Hits	62
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

F13B_HUMAN
NC score	0.776007 (rank : 4)	θ value	1.38178e-16 (rank : 6)
Query Neighborhood Hits	88	Target Neighborhood Hits	84	Shared Neighborhood Hits	61
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

C4BP_MOUSE
NC score	0.763589 (rank : 5)	θ value	3.52202e-12 (rank : 18)
Query Neighborhood Hits	88	Target Neighborhood Hits	91	Shared Neighborhood Hits	65
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

CFAH_MOUSE
NC score	0.759200 (rank : 6)	θ value	1.99529e-15 (rank : 8)
Query Neighborhood Hits	88	Target Neighborhood Hits	112	Shared Neighborhood Hits	65
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

CRRY_MOUSE
NC score	0.758943 (rank : 7)	θ value	4.59992e-12 (rank : 20)
Query Neighborhood Hits	88	Target Neighborhood Hits	84	Shared Neighborhood Hits	63
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

CR1_HUMAN
NC score	0.757635 (rank : 8)	θ value	1.42992e-13 (rank : 12)
Query Neighborhood Hits	88	Target Neighborhood Hits	108	Shared Neighborhood Hits	67
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

C4BP_HUMAN
NC score	0.757177 (rank : 9)	θ value	7.84624e-12 (rank : 21)
Query Neighborhood Hits	88	Target Neighborhood Hits	92	Shared Neighborhood Hits	64
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

CR2_HUMAN
NC score	0.755082 (rank : 10)	θ value	1.2105e-12 (rank : 16)
Query Neighborhood Hits	88	Target Neighborhood Hits	89	Shared Neighborhood Hits	64
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

CR2_MOUSE
NC score	0.754404 (rank : 11)	θ value	2.43908e-13 (rank : 14)
Query Neighborhood Hits	88	Target Neighborhood Hits	101	Shared Neighborhood Hits	64
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

ZP3R_MOUSE
NC score	0.749580 (rank : 12)	θ value	1.33837e-11 (rank : 24)
Query Neighborhood Hits	88	Target Neighborhood Hits	81	Shared Neighborhood Hits	62
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

CFAH_HUMAN
NC score	0.748502 (rank : 13)	θ value	2.43908e-13 (rank : 13)
Query Neighborhood Hits	88	Target Neighborhood Hits	101	Shared Neighborhood Hits	65
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

APOH_MOUSE
NC score	0.736256 (rank : 14)	θ value	8.97725e-08 (rank : 30)
Query Neighborhood Hits	88	Target Neighborhood Hits	74	Shared Neighborhood Hits	62
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

FHR5_HUMAN
NC score	0.732850 (rank : 15)	θ value	2.0648e-12 (rank : 17)
Query Neighborhood Hits	88	Target Neighborhood Hits	77	Shared Neighborhood Hits	60
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

MCP_HUMAN
NC score	0.727490 (rank : 16)	θ value	2.79066e-09 (rank : 28)
Query Neighborhood Hits	88	Target Neighborhood Hits	82	Shared Neighborhood Hits	61
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

APOH_HUMAN
NC score	0.725822 (rank : 17)	θ value	5.81887e-07 (rank : 33)
Query Neighborhood Hits	88	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

DAF_HUMAN
NC score	0.722002 (rank : 18)	θ value	1.99992e-07 (rank : 32)
Query Neighborhood Hits	88	Target Neighborhood Hits	97	Shared Neighborhood Hits	64
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

DAF2_MOUSE
NC score	0.721325 (rank : 19)	θ value	9.59137e-10 (rank : 27)
Query Neighborhood Hits	88	Target Neighborhood Hits	114	Shared Neighborhood Hits	63
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

DAF1_MOUSE
NC score	0.713448 (rank : 20)	θ value	3.89403e-11 (rank : 25)
Query Neighborhood Hits	88	Target Neighborhood Hits	204	Shared Neighborhood Hits	63
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

C4BB_HUMAN
NC score	0.704558 (rank : 21)	θ value	0.000461057 (rank : 44)
Query Neighborhood Hits	88	Target Neighborhood Hits	77	Shared Neighborhood Hits	61
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

FHR1_HUMAN
NC score	0.701808 (rank : 22)	θ value	1.17247e-07 (rank : 31)
Query Neighborhood Hits	88	Target Neighborhood Hits	80	Shared Neighborhood Hits	60
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

MCP_MOUSE
NC score	0.695780 (rank : 23)	θ value	5.44631e-05 (rank : 39)
Query Neighborhood Hits	88	Target Neighborhood Hits	79	Shared Neighborhood Hits	61
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

FHR3_HUMAN
NC score	0.690184 (rank : 24)	θ value	1.33837e-11 (rank : 22)
Query Neighborhood Hits	88	Target Neighborhood Hits	74	Shared Neighborhood Hits	58
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

FHR4_HUMAN
NC score	0.686213 (rank : 25)	θ value	1.47974e-10 (rank : 26)
Query Neighborhood Hits	88	Target Neighborhood Hits	75	Shared Neighborhood Hits	59
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

FHR2_HUMAN
NC score	0.665697 (rank : 26)	θ value	6.87365e-08 (rank : 29)
Query Neighborhood Hits	88	Target Neighborhood Hits	63	Shared Neighborhood Hits	55
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

LYAM3_HUMAN
NC score	0.627353 (rank : 27)	θ value	1.99529e-15 (rank : 9)
Query Neighborhood Hits	88	Target Neighborhood Hits	378	Shared Neighborhood Hits	64
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

K0247_HUMAN
NC score	0.621870 (rank : 28)	θ value	3.17815e-21 (rank : 3)
Query Neighborhood Hits	88	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	Q92537	Gene names	KIAA0247
Domain Architecture	No domain graphic available
Description	Protein KIAA0247 precursor.

SRPX_MOUSE
NC score	0.612856 (rank : 29)	θ value	3.19293e-05 (rank : 37)
Query Neighborhood Hits	88	Target Neighborhood Hits	75	Shared Neighborhood Hits	56
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

LYAM3_MOUSE
NC score	0.610263 (rank : 30)	θ value	3.52202e-12 (rank : 19)
Query Neighborhood Hits	88	Target Neighborhood Hits	390	Shared Neighborhood Hits	65
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

CSMD3_HUMAN
NC score	0.610235 (rank : 31)	θ value	1.63225e-17 (rank : 4)
Query Neighborhood Hits	88	Target Neighborhood Hits	199	Shared Neighborhood Hits	65
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

SRPX_HUMAN
NC score	0.602027 (rank : 32)	θ value	3.19293e-05 (rank : 36)
Query Neighborhood Hits	88	Target Neighborhood Hits	69	Shared Neighborhood Hits	57
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

LYAM2_HUMAN
NC score	0.597659 (rank : 33)	θ value	9.26847e-13 (rank : 15)
Query Neighborhood Hits	88	Target Neighborhood Hits	394	Shared Neighborhood Hits	65
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CSMD1_MOUSE
NC score	0.595324 (rank : 34)	θ value	5.25075e-16 (rank : 7)
Query Neighborhood Hits	88	Target Neighborhood Hits	193	Shared Neighborhood Hits	63
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_HUMAN
NC score	0.594436 (rank : 35)	θ value	6.41864e-14 (rank : 11)
Query Neighborhood Hits	88	Target Neighborhood Hits	176	Shared Neighborhood Hits	64
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

LYAM2_MOUSE
NC score	0.591137 (rank : 36)	θ value	1.33837e-11 (rank : 23)
Query Neighborhood Hits	88	Target Neighborhood Hits	420	Shared Neighborhood Hits	65
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CSMD2_HUMAN
NC score	0.587213 (rank : 37)	θ value	2.20605e-14 (rank : 10)
Query Neighborhood Hits	88	Target Neighborhood Hits	188	Shared Neighborhood Hits	64
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

SEZ6L_HUMAN
NC score	0.570541 (rank : 38)	θ value	5.81887e-07 (rank : 34)
Query Neighborhood Hits	88	Target Neighborhood Hits	289	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

PAPPA_HUMAN
NC score	0.477874 (rank : 39)	θ value	0.00102713 (rank : 45)
Query Neighborhood Hits	88	Target Neighborhood Hits	161	Shared Neighborhood Hits	54
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_MOUSE
NC score	0.471505 (rank : 40)	θ value	0.00020696 (rank : 43)
Query Neighborhood Hits	88	Target Neighborhood Hits	153	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAP2_HUMAN
NC score	0.449588 (rank : 41)	θ value	4.1701e-05 (rank : 38)
Query Neighborhood Hits	88	Target Neighborhood Hits	106	Shared Neighborhood Hits	49
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

LYAM1_HUMAN
NC score	0.402074 (rank : 42)	θ value	0.279714 (rank : 59)
Query Neighborhood Hits	88	Target Neighborhood Hits	315	Shared Neighborhood Hits	53
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM1_MOUSE
NC score	0.390249 (rank : 43)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	88	Target Neighborhood Hits	332	Shared Neighborhood Hits	54
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

CO2_HUMAN
NC score	0.381338 (rank : 44)	θ value	0.000121331 (rank : 40)
Query Neighborhood Hits	88	Target Neighborhood Hits	258	Shared Neighborhood Hits	60
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CFAB_MOUSE
NC score	0.371384 (rank : 45)	θ value	0.00298849 (rank : 46)
Query Neighborhood Hits	88	Target Neighborhood Hits	262	Shared Neighborhood Hits	64
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_HUMAN
NC score	0.369201 (rank : 46)	θ value	0.00390308 (rank : 48)
Query Neighborhood Hits	88	Target Neighborhood Hits	251	Shared Neighborhood Hits	64
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CO7_HUMAN
NC score	0.340556 (rank : 47)	θ value	0.000158464 (rank : 42)
Query Neighborhood Hits	88	Target Neighborhood Hits	278	Shared Neighborhood Hits	48
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO2_MOUSE
NC score	0.324823 (rank : 48)	θ value	0.000158464 (rank : 41)
Query Neighborhood Hits	88	Target Neighborhood Hits	250	Shared Neighborhood Hits	60
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

SUSD2_MOUSE
NC score	0.324745 (rank : 49)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	88	Target Neighborhood Hits	104	Shared Neighborhood Hits	58
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SUSD2_HUMAN
NC score	0.317986 (rank : 50)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	88	Target Neighborhood Hits	99	Shared Neighborhood Hits	60
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

CO6_HUMAN
NC score	0.306314 (rank : 51)	θ value	8.40245e-06 (rank : 35)
Query Neighborhood Hits	88	Target Neighborhood Hits	331	Shared Neighborhood Hits	56
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

GABR1_HUMAN
NC score	0.272506 (rank : 52)	θ value	0.0736092 (rank : 53)
Query Neighborhood Hits	88	Target Neighborhood Hits	142	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
NC score	0.271230 (rank : 53)	θ value	0.0736092 (rank : 54)
Query Neighborhood Hits	88	Target Neighborhood Hits	139	Shared Neighborhood Hits	48
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

SUSD3_MOUSE
NC score	0.270398 (rank : 54)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	88	Target Neighborhood Hits	39	Shared Neighborhood Hits	35
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

SUSD1_HUMAN
NC score	0.202360 (rank : 55)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	88	Target Neighborhood Hits	285	Shared Neighborhood Hits	51
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

PERT_MOUSE
NC score	0.178410 (rank : 56)	θ value	0.0252991 (rank : 50)
Query Neighborhood Hits	88	Target Neighborhood Hits	221	Shared Neighborhood Hits	51
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

MASP2_MOUSE
NC score	0.175191 (rank : 57)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	88	Target Neighborhood Hits	382	Shared Neighborhood Hits	59
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

C1S_HUMAN
NC score	0.158852 (rank : 58)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	88	Target Neighborhood Hits	359	Shared Neighborhood Hits	53
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

C1RA_MOUSE
NC score	0.156588 (rank : 59)	θ value	0.00869519 (rank : 49)
Query Neighborhood Hits	88	Target Neighborhood Hits	379	Shared Neighborhood Hits	49
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

CS1B_MOUSE
NC score	0.155538 (rank : 60)	θ value	0.0961366 (rank : 55)
Query Neighborhood Hits	88	Target Neighborhood Hits	361	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

MASP2_HUMAN
NC score	0.155257 (rank : 61)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	88	Target Neighborhood Hits	364	Shared Neighborhood Hits	55
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

CS1A_MOUSE
NC score	0.155183 (rank : 62)	θ value	0.125558 (rank : 56)
Query Neighborhood Hits	88	Target Neighborhood Hits	360	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

SUSD3_HUMAN
NC score	0.153779 (rank : 63)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	88	Target Neighborhood Hits	32	Shared Neighborhood Hits	27
SwissProt Accessions	Q96L08, Q49AA6, Q6UXV7	Gene names	SUSD3, UNQ9387/PRO34275
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

MASP1_HUMAN
NC score	0.153468 (rank : 64)	θ value	0.0431538 (rank : 51)
Query Neighborhood Hits	88	Target Neighborhood Hits	369	Shared Neighborhood Hits	56
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

C1RB_MOUSE
NC score	0.153001 (rank : 65)	θ value	0.0563607 (rank : 52)
Query Neighborhood Hits	88	Target Neighborhood Hits	380	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1R_HUMAN
NC score	0.150441 (rank : 66)	θ value	0.00390308 (rank : 47)
Query Neighborhood Hits	88	Target Neighborhood Hits	364	Shared Neighborhood Hits	48
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

PERT_HUMAN
NC score	0.147843 (rank : 67)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	88	Target Neighborhood Hits	221	Shared Neighborhood Hits	50
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

MASP1_MOUSE
NC score	0.144586 (rank : 68)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	88	Target Neighborhood Hits	364	Shared Neighborhood Hits	52
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

TLL2_MOUSE
NC score	0.105553 (rank : 69)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	88	Target Neighborhood Hits	240	Shared Neighborhood Hits	19
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL1_MOUSE
NC score	0.104898 (rank : 70)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	88	Target Neighborhood Hits	237	Shared Neighborhood Hits	18
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL1_HUMAN
NC score	0.102943 (rank : 71)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	88	Target Neighborhood Hits	236	Shared Neighborhood Hits	17
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL2_HUMAN
NC score	0.102689 (rank : 72)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	88	Target Neighborhood Hits	241	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

BMP1_MOUSE
NC score	0.102647 (rank : 73)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	88	Target Neighborhood Hits	236	Shared Neighborhood Hits	17
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_HUMAN
NC score	0.102228 (rank : 74)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	88	Target Neighborhood Hits	233	Shared Neighborhood Hits	17
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

IL2RA_HUMAN
NC score	0.101777 (rank : 75)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	88	Target Neighborhood Hits	32	Shared Neighborhood Hits	18
SwissProt Accessions	P01589	Gene names	IL2RA
Domain Architecture
Description	Interleukin-2 receptor alpha chain precursor (IL-2 receptor alpha subunit) (IL-2-RA) (IL2-RA) (p55) (TAC antigen) (CD25 antigen).

CSPG3_MOUSE
NC score	0.101368 (rank : 76)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	88	Target Neighborhood Hits	657	Shared Neighborhood Hits	48
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

PCOC1_HUMAN
NC score	0.100072 (rank : 77)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	88	Target Neighborhood Hits	146	Shared Neighborhood Hits	12
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
NC score	0.099197 (rank : 78)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	88	Target Neighborhood Hits	100	Shared Neighborhood Hits	11
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

CSPG3_HUMAN
NC score	0.093120 (rank : 79)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	88	Target Neighborhood Hits	676	Shared Neighborhood Hits	49
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

MFRP_MOUSE
NC score	0.092077 (rank : 80)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	88	Target Neighborhood Hits	166	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

PCOC2_HUMAN
NC score	0.092020 (rank : 81)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	88	Target Neighborhood Hits	73	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
NC score	0.089912 (rank : 82)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	88	Target Neighborhood Hits	73	Shared Neighborhood Hits	11
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

MFRP_HUMAN
NC score	0.089664 (rank : 83)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	88	Target Neighborhood Hits	165	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

HPT_HUMAN
NC score	0.088933 (rank : 84)	θ value	0.125558 (rank : 57)
Query Neighborhood Hits	88	Target Neighborhood Hits	184	Shared Neighborhood Hits	29
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

CUBN_HUMAN
NC score	0.088745 (rank : 85)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	88	Target Neighborhood Hits	482	Shared Neighborhood Hits	24
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

PGCA_MOUSE
NC score	0.086730 (rank : 86)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	88	Target Neighborhood Hits	643	Shared Neighborhood Hits	44
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PGCB_HUMAN
NC score	0.086660 (rank : 87)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	88	Target Neighborhood Hits	478	Shared Neighborhood Hits	43
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

CSPG2_MOUSE
NC score	0.084128 (rank : 88)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	88	Target Neighborhood Hits	711	Shared Neighborhood Hits	42
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

TSG6_MOUSE
NC score	0.083893 (rank : 89)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	88	Target Neighborhood Hits	91	Shared Neighborhood Hits	13
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

CSPG2_HUMAN
NC score	0.083812 (rank : 90)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	88	Target Neighborhood Hits	681	Shared Neighborhood Hits	42
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

TSG6_HUMAN
NC score	0.082646 (rank : 91)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	88	Target Neighborhood Hits	91	Shared Neighborhood Hits	13
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

CUZD1_HUMAN
NC score	0.080722 (rank : 92)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	88	Target Neighborhood Hits	89	Shared Neighborhood Hits	11
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUBN_MOUSE
NC score	0.080499 (rank : 93)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	88	Target Neighborhood Hits	477	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

PGCA_HUMAN
NC score	0.080493 (rank : 94)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	88	Target Neighborhood Hits	821	Shared Neighborhood Hits	47
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

LRP12_HUMAN
NC score	0.078699 (rank : 95)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	88	Target Neighborhood Hits	205	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
NC score	0.078375 (rank : 96)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	88	Target Neighborhood Hits	180	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

PGCB_MOUSE
NC score	0.077945 (rank : 97)	θ value	4.03905 (rank : 76)
Query Neighborhood Hits	88	Target Neighborhood Hits	459	Shared Neighborhood Hits	43
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

NRP2_MOUSE
NC score	0.077924 (rank : 98)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	88	Target Neighborhood Hits	113	Shared Neighborhood Hits	11
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

PDGFD_HUMAN
NC score	0.077631 (rank : 99)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	88	Target Neighborhood Hits	74	Shared Neighborhood Hits	11
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

NETO1_HUMAN
NC score	0.077270 (rank : 100)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	88	Target Neighborhood Hits	110	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NRP2_HUMAN
NC score	0.076929 (rank : 101)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	88	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NETO1_MOUSE
NC score	0.076650 (rank : 102)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	88	Target Neighborhood Hits	109	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

KREM1_HUMAN
NC score	0.075535 (rank : 103)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	88	Target Neighborhood Hits	90	Shared Neighborhood Hits	11
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

CUZD1_MOUSE
NC score	0.075307 (rank : 104)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	88	Target Neighborhood Hits	91	Shared Neighborhood Hits	11
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

PDGFD_MOUSE
NC score	0.074406 (rank : 105)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	88	Target Neighborhood Hits	72	Shared Neighborhood Hits	10
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

KREM2_HUMAN
NC score	0.074336 (rank : 106)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	88	Target Neighborhood Hits	93	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KREM1_MOUSE
NC score	0.074169 (rank : 107)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	88	Target Neighborhood Hits	92	Shared Neighborhood Hits	11
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

NETO2_HUMAN
NC score	0.073896 (rank : 108)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	88	Target Neighborhood Hits	109	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

DMBT1_MOUSE
NC score	0.073093 (rank : 109)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	88	Target Neighborhood Hits	134	Shared Neighborhood Hits	11
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

NETO2_MOUSE
NC score	0.072921 (rank : 110)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	88	Target Neighborhood Hits	113	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NRP1_MOUSE
NC score	0.069852 (rank : 111)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	88	Target Neighborhood Hits	120	Shared Neighborhood Hits	11
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

KREM2_MOUSE
NC score	0.069116 (rank : 112)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	88	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

NRP1_HUMAN
NC score	0.068835 (rank : 113)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	88	Target Neighborhood Hits	119	Shared Neighborhood Hits	11
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

DCBD1_MOUSE
NC score	0.066220 (rank : 114)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	88	Target Neighborhood Hits	89	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
NC score	0.060320 (rank : 115)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	88	Target Neighborhood Hits	118	Shared Neighborhood Hits	11
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DMBT1_HUMAN
NC score	0.059726 (rank : 116)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	88	Target Neighborhood Hits	152	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

LRP3_HUMAN
NC score	0.055642 (rank : 117)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	88	Target Neighborhood Hits	280	Shared Neighborhood Hits	13
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

ATRN_HUMAN
NC score	0.055568 (rank : 118)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	88	Target Neighborhood Hits	525	Shared Neighborhood Hits	14
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

DCBD2_MOUSE
NC score	0.054721 (rank : 119)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	88	Target Neighborhood Hits	113	Shared Neighborhood Hits	11
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

ATRN_MOUSE
NC score	0.053681 (rank : 120)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	88	Target Neighborhood Hits	519	Shared Neighborhood Hits	15
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

CB017_HUMAN
NC score	0.052209 (rank : 121)	θ value	1.38821 (rank : 62)
Query Neighborhood Hits	88	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NC44, Q6P1P5, Q9H0K7	Gene names	C2orf17
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf17.

GP126_HUMAN
NC score	0.051049 (rank : 122)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	88	Target Neighborhood Hits	187	Shared Neighborhood Hits	11
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

DCBD1_HUMAN
NC score	0.050887 (rank : 123)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	88	Target Neighborhood Hits	110	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

MAVS_MOUSE
NC score	0.049833 (rank : 124)	θ value	0.21417 (rank : 58)
Query Neighborhood Hits	88	Target Neighborhood Hits	170	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

CABL1_HUMAN
NC score	0.045168 (rank : 125)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	88	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDN4, Q8N3Y8, Q8NA22, Q9BTG1	Gene names	CABLES1, CABLES
Domain Architecture	No domain graphic available
Description	CDK5 and ABL1 enzyme substrate 1 (Interactor with CDK3 1) (Ik3-1).

WFD13_HUMAN
NC score	0.033927 (rank : 126)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	88	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IUB5, Q5TEU7, Q8WWK7	Gene names	WFDC13, C20orf138, WAP13
Domain Architecture	No domain graphic available
Description	Protein WFDC13 precursor.

FBLN2_MOUSE
NC score	0.027560 (rank : 127)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	88	Target Neighborhood Hits	505	Shared Neighborhood Hits	25
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

POLS2_MOUSE
NC score	0.024477 (rank : 128)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	88	Target Neighborhood Hits	188	Shared Neighborhood Hits	13
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

DMP1_HUMAN
NC score	0.023846 (rank : 129)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	88	Target Neighborhood Hits	491	Shared Neighborhood Hits	4
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

DPP9_MOUSE
NC score	0.019522 (rank : 130)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	88	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BVG4, Q6KAM9, Q8BWT9	Gene names	Dpp9
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9).

DPP9_HUMAN
NC score	0.019500 (rank : 131)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	88	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q86TI2, Q6AI37, Q6UAL0, Q6ZMT2, Q6ZNJ5, Q8N2J7, Q8N3F5, Q8WXD8, Q96NT8, Q9BVR3	Gene names	DPP9, DPRP2
Domain Architecture	No domain graphic available
Description	Dipeptidyl peptidase 9 (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DP9) (Dipeptidyl peptidase-like protein 9) (DPLP9) (Dipeptidyl peptidase IV-related protein 2) (DPRP-2).

GLSK_HUMAN
NC score	0.019109 (rank : 132)	θ value	0.813845 (rank : 61)
Query Neighborhood Hits	88	Target Neighborhood Hits	204	Shared Neighborhood Hits	2
SwissProt Accessions	O94925, Q9UL05, Q9UL06, Q9UL07, Q9UN40	Gene names	GLS, GLS1, KIAA0838
Domain Architecture
Description	Glutaminase kidney isoform, mitochondrial precursor (EC 3.5.1.2) (GLS) (L-glutamine amidohydrolase) (K-glutaminase).

CDSN_MOUSE
NC score	0.015078 (rank : 133)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	88	Target Neighborhood Hits	131	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TPC1	Gene names	Cdsn
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor.

RBM10_HUMAN
NC score	0.013210 (rank : 134)	θ value	3.0926 (rank : 72)
Query Neighborhood Hits	88	Target Neighborhood Hits	204	Shared Neighborhood Hits	2
SwissProt Accessions	P98175, Q14136	Gene names	RBM10, DXS8237E, KIAA0122
Domain Architecture
Description	RNA-binding protein 10 (RNA-binding motif protein 10).

SMAD5_MOUSE
NC score	0.011029 (rank : 135)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	88	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	P97454, P70341, Q810K0	Gene names	Smad5, Madh5, Msmad5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (mSmad5) (Dwarfin-C) (Dwf-C).

MAP1A_HUMAN
NC score	0.009256 (rank : 136)	θ value	3.0926 (rank : 71)
Query Neighborhood Hits	88	Target Neighborhood Hits	1626	Shared Neighborhood Hits	8
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

ITIH4_HUMAN
NC score	0.009028 (rank : 137)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	88	Target Neighborhood Hits	46	Shared Neighborhood Hits	2
SwissProt Accessions	Q14624, Q15135, Q9P190, Q9UQ54	Gene names	ITIH4, IHRP, ITIHL1, PK120
Domain Architecture
Description	Inter-alpha-trypsin inhibitor heavy chain H4 precursor (ITI heavy chain H4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (PK-120) (GP120) [Contains: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha- trypsin inhibitor heavy chain H4].

FOXC1_MOUSE
NC score	0.007851 (rank : 138)	θ value	3.0926 (rank : 70)
Query Neighborhood Hits	88	Target Neighborhood Hits	218	Shared Neighborhood Hits	6
SwissProt Accessions	Q61572, O88409, Q61582	Gene names	Foxc1, Fkh1, Fkhl7, Freac3, Mf1
Domain Architecture
Description	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead- related transcription factor 3) (FREAC-3) (Transcription factor FKH-1) (Mesoderm/mesenchyme forkhead 1) (MF-1).

LRC19_MOUSE
NC score	0.005631 (rank : 139)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	88	Target Neighborhood Hits	238	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BZT5, Q6P8J1	Gene names	Lrrc19
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 19 precursor.

UBQL1_MOUSE
NC score	0.004954 (rank : 140)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	88	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R317, Q80V10, Q8C7T4, Q8C835, Q8K141, Q91VI8, Q9D0Z0, Q9QZM1	Gene names	Ubqln1, Plic1
Domain Architecture
Description	Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1).

SRRM2_MOUSE
NC score	0.004665 (rank : 141)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	88	Target Neighborhood Hits	1470	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

FGD5_HUMAN
NC score	0.003228 (rank : 142)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	88	Target Neighborhood Hits	235	Shared Neighborhood Hits	2
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

CDX4_MOUSE
NC score	0.002792 (rank : 143)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	88	Target Neighborhood Hits	378	Shared Neighborhood Hits	4
SwissProt Accessions	Q07424	Gene names	Cdx4, Cdx-4
Domain Architecture
Description	Homeobox protein CDX-4 (Caudal-type homeobox protein 4).

ZBT16_HUMAN
NC score	-0.001665 (rank : 144)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	88	Target Neighborhood Hits	1010	Shared Neighborhood Hits	7
SwissProt Accessions	Q05516, Q8TAL4	Gene names	ZBTB16, PLZF, ZNF145
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 16 (Zinc finger protein PLZF) (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145).

ZN484_HUMAN
NC score	-0.003023 (rank : 145)	θ value	1.38821 (rank : 63)
Query Neighborhood Hits	88	Target Neighborhood Hits	766	Shared Neighborhood Hits	3
SwissProt Accessions	Q5JVG2	Gene names	ZNF484
Domain Architecture	No domain graphic available
Description	Zinc finger protein 484.