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Network neighborhood for query Sequence : K0247_HUMAN

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K0247_HUMAN
SwissProt Accessions	Q92537	Gene names	KIAA0247
Domain Architecture	No domain graphic available
Description	Protein KIAA0247 precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

K0247_HUMAN
θ value	2.67036e-161 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q92537	Gene names	KIAA0247
Domain Architecture	No domain graphic available
Description	Protein KIAA0247 precursor.

SUSD4_MOUSE
θ value	5.23862e-24 (rank : 2)	NC score	0.627835 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	122	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

SUSD4_HUMAN
θ value	3.17815e-21 (rank : 3)	NC score	0.621870 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	88	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

CFAH_MOUSE
θ value	0.00298849 (rank : 4)	NC score	0.317572 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	112	Shared Neighborhood Hits	31
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

APOH_MOUSE
θ value	0.0113563 (rank : 5)	NC score	0.299468 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	74	Shared Neighborhood Hits	30
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

CFAH_HUMAN
θ value	0.0252991 (rank : 6)	NC score	0.306336 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	101	Shared Neighborhood Hits	30
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

FHR1_HUMAN
θ value	0.0252991 (rank : 7)	NC score	0.324922 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	80	Shared Neighborhood Hits	30
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

F13B_MOUSE
θ value	0.0563607 (rank : 8)	NC score	0.318884 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	93	Shared Neighborhood Hits	30
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

CSMD3_HUMAN
θ value	0.125558 (rank : 9)	NC score	0.203116 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	199	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

FHR2_HUMAN
θ value	0.125558 (rank : 10)	NC score	0.309527 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	63	Shared Neighborhood Hits	29
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

CR2_HUMAN
θ value	0.163984 (rank : 11)	NC score	0.265960 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	89	Shared Neighborhood Hits	30
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

SRPX_HUMAN
θ value	0.163984 (rank : 12)	NC score	0.259868 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	69	Shared Neighborhood Hits	29
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

SRPX_MOUSE
θ value	0.163984 (rank : 13)	NC score	0.264243 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	75	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

F13B_HUMAN
θ value	0.21417 (rank : 14)	NC score	0.315690 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	84	Shared Neighborhood Hits	30
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

PTC1_HUMAN
θ value	0.21417 (rank : 15)	NC score	0.051072 (rank : 60)
Query Neighborhood Hits	42	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q13635, Q13463, Q5VZC0	Gene names	PTCH1, PTCH
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

SFRP1_HUMAN
θ value	0.21417 (rank : 16)	NC score	0.058802 (rank : 57)
Query Neighborhood Hits	42	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N474, O00546, O14779	Gene names	SFRP1, FRP, FRP1, SARP2
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1) (Frizzled- related protein 1) (FRP-1) (Secreted apoptosis-related protein 2) (SARP-2).

SFRP1_MOUSE
θ value	0.21417 (rank : 17)	NC score	0.059304 (rank : 56)
Query Neighborhood Hits	42	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C4U3, O08861, Q8R1J4	Gene names	Sfrp1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1).

LYAM2_MOUSE
θ value	0.279714 (rank : 18)	NC score	0.209645 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	420	Shared Neighborhood Hits	31
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

APOH_HUMAN
θ value	0.365318 (rank : 19)	NC score	0.285803 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	75	Shared Neighborhood Hits	30
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

CR1_HUMAN
θ value	0.365318 (rank : 20)	NC score	0.262615 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	108	Shared Neighborhood Hits	30
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

CSMD2_HUMAN
θ value	0.365318 (rank : 21)	NC score	0.190093 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	188	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

LYAM2_HUMAN
θ value	0.62314 (rank : 22)	NC score	0.210649 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	394	Shared Neighborhood Hits	31
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

FHR4_HUMAN
θ value	0.813845 (rank : 23)	NC score	0.310502 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	75	Shared Neighborhood Hits	30
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

IF39_HUMAN
θ value	0.813845 (rank : 24)	NC score	0.050874 (rank : 61)
Query Neighborhood Hits	42	Target Neighborhood Hits	187	Shared Neighborhood Hits	2
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

CR2_MOUSE
θ value	1.38821 (rank : 25)	NC score	0.259729 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	101	Shared Neighborhood Hits	30
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

FHR3_HUMAN
θ value	1.38821 (rank : 26)	NC score	0.309683 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	74	Shared Neighborhood Hits	30
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

LYAM3_MOUSE
θ value	1.81305 (rank : 27)	NC score	0.208359 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	390	Shared Neighborhood Hits	31
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

C4BP_MOUSE
θ value	3.0926 (rank : 28)	NC score	0.259973 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	91	Shared Neighborhood Hits	30
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

HXA5_MOUSE
θ value	4.03905 (rank : 29)	NC score	0.007382 (rank : 68)
Query Neighborhood Hits	42	Target Neighborhood Hits	338	Shared Neighborhood Hits	2
SwissProt Accessions	P09021, Q91VQ5	Gene names	Hoxa5, Hox-1.3, Hoxa-5
Domain Architecture
Description	Homeobox protein Hox-A5 (Hox-1.3) (M2).

PERT_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.081821 (rank : 52)
Query Neighborhood Hits	42	Target Neighborhood Hits	221	Shared Neighborhood Hits	29
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

ZCH10_MOUSE
θ value	4.03905 (rank : 31)	NC score	0.042503 (rank : 62)
Query Neighborhood Hits	42	Target Neighborhood Hits	133	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

CFAB_MOUSE
θ value	5.27518 (rank : 32)	NC score	0.114406 (rank : 43)
Query Neighborhood Hits	42	Target Neighborhood Hits	262	Shared Neighborhood Hits	29
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CO6_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.108844 (rank : 48)
Query Neighborhood Hits	42	Target Neighborhood Hits	331	Shared Neighborhood Hits	27
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

FETUB_MOUSE
θ value	5.27518 (rank : 34)	NC score	0.027589 (rank : 63)
Query Neighborhood Hits	42	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXC1	Gene names	Fetub
Domain Architecture
Description	Fetuin-B precursor (IRL685).

LTBP4_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.011264 (rank : 67)
Query Neighborhood Hits	42	Target Neighborhood Hits	607	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

NIBA_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.026308 (rank : 64)
Query Neighborhood Hits	42	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZQ8, Q5TEM8, Q8TEI5, Q9H593, Q9H9Y8, Q9HCB9	Gene names	C1orf24
Domain Architecture	No domain graphic available
Description	Niban protein.

SNTA1_HUMAN
θ value	5.27518 (rank : 37)	NC score	0.013091 (rank : 66)
Query Neighborhood Hits	42	Target Neighborhood Hits	186	Shared Neighborhood Hits	2
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

CFAB_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.114042 (rank : 44)
Query Neighborhood Hits	42	Target Neighborhood Hits	251	Shared Neighborhood Hits	30
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

M3K14_MOUSE
θ value	6.88961 (rank : 39)	NC score	0.002393 (rank : 69)
Query Neighborhood Hits	42	Target Neighborhood Hits	889	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WUL6	Gene names	Map3k14, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK).

ZP3R_MOUSE
θ value	6.88961 (rank : 40)	NC score	0.238649 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	81	Shared Neighborhood Hits	29
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

DAF_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.222751 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	97	Shared Neighborhood Hits	30
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

RIN1_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.015107 (rank : 65)
Query Neighborhood Hits	42	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q13671, O15010, Q00427, Q96CC8	Gene names	RIN1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1) (Ras inhibitor JC99).

C4BB_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.223899 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	77	Shared Neighborhood Hits	29
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

C4BP_HUMAN
θ value	θ > 10 (rank : 44)	NC score	0.241884 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	92	Shared Neighborhood Hits	29
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

CO2_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.113354 (rank : 45)
Query Neighborhood Hits	42	Target Neighborhood Hits	258	Shared Neighborhood Hits	27
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO2_MOUSE
θ value	θ > 10 (rank : 46)	NC score	0.096608 (rank : 50)
Query Neighborhood Hits	42	Target Neighborhood Hits	250	Shared Neighborhood Hits	26
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO7_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.109643 (rank : 47)
Query Neighborhood Hits	42	Target Neighborhood Hits	278	Shared Neighborhood Hits	27
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CRRY_MOUSE
θ value	θ > 10 (rank : 48)	NC score	0.246356 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	84	Shared Neighborhood Hits	29
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

CSMD1_HUMAN
θ value	θ > 10 (rank : 49)	NC score	0.180389 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	176	Shared Neighborhood Hits	29
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
θ value	θ > 10 (rank : 50)	NC score	0.182821 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	193	Shared Neighborhood Hits	29
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

DAF1_MOUSE
θ value	θ > 10 (rank : 51)	NC score	0.220195 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	204	Shared Neighborhood Hits	29
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

DAF2_MOUSE
θ value	θ > 10 (rank : 52)	NC score	0.222300 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	114	Shared Neighborhood Hits	29
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

FHR5_HUMAN
θ value	θ > 10 (rank : 53)	NC score	0.288845 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	77	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

GABR1_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.080914 (rank : 53)
Query Neighborhood Hits	42	Target Neighborhood Hits	142	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.080520 (rank : 54)
Query Neighborhood Hits	42	Target Neighborhood Hits	139	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

LYAM1_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.121855 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	315	Shared Neighborhood Hits	27
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM1_MOUSE
θ value	θ > 10 (rank : 57)	NC score	0.111864 (rank : 46)
Query Neighborhood Hits	42	Target Neighborhood Hits	332	Shared Neighborhood Hits	24
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM3_HUMAN
θ value	θ > 10 (rank : 58)	NC score	0.211149 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	378	Shared Neighborhood Hits	30
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MCP_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.239686 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	82	Shared Neighborhood Hits	29
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

MCP_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.214157 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	79	Shared Neighborhood Hits	28
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

PAP2_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.134363 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	106	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

PAPPA_HUMAN
θ value	θ > 10 (rank : 62)	NC score	0.133992 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	161	Shared Neighborhood Hits	29
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_MOUSE
θ value	θ > 10 (rank : 63)	NC score	0.132486 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	153	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PERT_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.056256 (rank : 58)
Query Neighborhood Hits	42	Target Neighborhood Hits	221	Shared Neighborhood Hits	27
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

SEZ6L_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.174769 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	289	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SUSD1_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.052103 (rank : 59)
Query Neighborhood Hits	42	Target Neighborhood Hits	285	Shared Neighborhood Hits	22
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

SUSD2_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.089874 (rank : 51)
Query Neighborhood Hits	42	Target Neighborhood Hits	99	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SUSD2_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.097003 (rank : 49)
Query Neighborhood Hits	42	Target Neighborhood Hits	104	Shared Neighborhood Hits	29
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SUSD3_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.070936 (rank : 55)
Query Neighborhood Hits	42	Target Neighborhood Hits	39	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

Hits sorted by NC score

K0247_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.67036e-161 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	Q92537	Gene names	KIAA0247
Domain Architecture	No domain graphic available
Description	Protein KIAA0247 precursor.

SUSD4_MOUSE
NC score	0.627835 (rank : 2)	θ value	5.23862e-24 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	122	Shared Neighborhood Hits	30
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

SUSD4_HUMAN
NC score	0.621870 (rank : 3)	θ value	3.17815e-21 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	88	Shared Neighborhood Hits	30
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

FHR1_HUMAN
NC score	0.324922 (rank : 4)	θ value	0.0252991 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	80	Shared Neighborhood Hits	30
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

F13B_MOUSE
NC score	0.318884 (rank : 5)	θ value	0.0563607 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	93	Shared Neighborhood Hits	30
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

CFAH_MOUSE
NC score	0.317572 (rank : 6)	θ value	0.00298849 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	112	Shared Neighborhood Hits	31
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

F13B_HUMAN
NC score	0.315690 (rank : 7)	θ value	0.21417 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	84	Shared Neighborhood Hits	30
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

FHR4_HUMAN
NC score	0.310502 (rank : 8)	θ value	0.813845 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	75	Shared Neighborhood Hits	30
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

FHR3_HUMAN
NC score	0.309683 (rank : 9)	θ value	1.38821 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	74	Shared Neighborhood Hits	30
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

FHR2_HUMAN
NC score	0.309527 (rank : 10)	θ value	0.125558 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	63	Shared Neighborhood Hits	29
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

CFAH_HUMAN
NC score	0.306336 (rank : 11)	θ value	0.0252991 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	101	Shared Neighborhood Hits	30
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

APOH_MOUSE
NC score	0.299468 (rank : 12)	θ value	0.0113563 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	74	Shared Neighborhood Hits	30
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

FHR5_HUMAN
NC score	0.288845 (rank : 13)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	42	Target Neighborhood Hits	77	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

APOH_HUMAN
NC score	0.285803 (rank : 14)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	75	Shared Neighborhood Hits	30
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

CR2_HUMAN
NC score	0.265960 (rank : 15)	θ value	0.163984 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	89	Shared Neighborhood Hits	30
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

SRPX_MOUSE
NC score	0.264243 (rank : 16)	θ value	0.163984 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	75	Shared Neighborhood Hits	29
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

CR1_HUMAN
NC score	0.262615 (rank : 17)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	108	Shared Neighborhood Hits	30
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

C4BP_MOUSE
NC score	0.259973 (rank : 18)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	91	Shared Neighborhood Hits	30
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

SRPX_HUMAN
NC score	0.259868 (rank : 19)	θ value	0.163984 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	69	Shared Neighborhood Hits	29
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

CR2_MOUSE
NC score	0.259729 (rank : 20)	θ value	1.38821 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	101	Shared Neighborhood Hits	30
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

CRRY_MOUSE
NC score	0.246356 (rank : 21)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	42	Target Neighborhood Hits	84	Shared Neighborhood Hits	29
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

C4BP_HUMAN
NC score	0.241884 (rank : 22)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	42	Target Neighborhood Hits	92	Shared Neighborhood Hits	29
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

MCP_HUMAN
NC score	0.239686 (rank : 23)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	42	Target Neighborhood Hits	82	Shared Neighborhood Hits	29
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

ZP3R_MOUSE
NC score	0.238649 (rank : 24)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	81	Shared Neighborhood Hits	29
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

C4BB_HUMAN
NC score	0.223899 (rank : 25)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	42	Target Neighborhood Hits	77	Shared Neighborhood Hits	29
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

DAF_HUMAN
NC score	0.222751 (rank : 26)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	97	Shared Neighborhood Hits	30
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

DAF2_MOUSE
NC score	0.222300 (rank : 27)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	42	Target Neighborhood Hits	114	Shared Neighborhood Hits	29
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

DAF1_MOUSE
NC score	0.220195 (rank : 28)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	42	Target Neighborhood Hits	204	Shared Neighborhood Hits	29
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

MCP_MOUSE
NC score	0.214157 (rank : 29)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	42	Target Neighborhood Hits	79	Shared Neighborhood Hits	28
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

LYAM3_HUMAN
NC score	0.211149 (rank : 30)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	42	Target Neighborhood Hits	378	Shared Neighborhood Hits	30
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM2_HUMAN
NC score	0.210649 (rank : 31)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	394	Shared Neighborhood Hits	31
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM2_MOUSE
NC score	0.209645 (rank : 32)	θ value	0.279714 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	420	Shared Neighborhood Hits	31
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_MOUSE
NC score	0.208359 (rank : 33)	θ value	1.81305 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	390	Shared Neighborhood Hits	31
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

CSMD3_HUMAN
NC score	0.203116 (rank : 34)	θ value	0.125558 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	199	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSMD2_HUMAN
NC score	0.190093 (rank : 35)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	188	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD1_MOUSE
NC score	0.182821 (rank : 36)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	42	Target Neighborhood Hits	193	Shared Neighborhood Hits	29
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_HUMAN
NC score	0.180389 (rank : 37)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	42	Target Neighborhood Hits	176	Shared Neighborhood Hits	29
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

SEZ6L_HUMAN
NC score	0.174769 (rank : 38)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	42	Target Neighborhood Hits	289	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

PAP2_HUMAN
NC score	0.134363 (rank : 39)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	42	Target Neighborhood Hits	106	Shared Neighborhood Hits	28
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

PAPPA_HUMAN
NC score	0.133992 (rank : 40)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	42	Target Neighborhood Hits	161	Shared Neighborhood Hits	29
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_MOUSE
NC score	0.132486 (rank : 41)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	42	Target Neighborhood Hits	153	Shared Neighborhood Hits	29
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

LYAM1_HUMAN
NC score	0.121855 (rank : 42)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	42	Target Neighborhood Hits	315	Shared Neighborhood Hits	27
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

CFAB_MOUSE
NC score	0.114406 (rank : 43)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	262	Shared Neighborhood Hits	29
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_HUMAN
NC score	0.114042 (rank : 44)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	251	Shared Neighborhood Hits	30
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CO2_HUMAN
NC score	0.113354 (rank : 45)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	42	Target Neighborhood Hits	258	Shared Neighborhood Hits	27
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

LYAM1_MOUSE
NC score	0.111864 (rank : 46)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	42	Target Neighborhood Hits	332	Shared Neighborhood Hits	24
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

CO7_HUMAN
NC score	0.109643 (rank : 47)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	42	Target Neighborhood Hits	278	Shared Neighborhood Hits	27
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO6_HUMAN
NC score	0.108844 (rank : 48)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	331	Shared Neighborhood Hits	27
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

SUSD2_MOUSE
NC score	0.097003 (rank : 49)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	42	Target Neighborhood Hits	104	Shared Neighborhood Hits	29
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

CO2_MOUSE
NC score	0.096608 (rank : 50)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	42	Target Neighborhood Hits	250	Shared Neighborhood Hits	26
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

SUSD2_HUMAN
NC score	0.089874 (rank : 51)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	42	Target Neighborhood Hits	99	Shared Neighborhood Hits	29
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

PERT_MOUSE
NC score	0.081821 (rank : 52)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	221	Shared Neighborhood Hits	29
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

GABR1_HUMAN
NC score	0.080914 (rank : 53)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	42	Target Neighborhood Hits	142	Shared Neighborhood Hits	28
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
NC score	0.080520 (rank : 54)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	42	Target Neighborhood Hits	139	Shared Neighborhood Hits	28
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

SUSD3_MOUSE
NC score	0.070936 (rank : 55)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	42	Target Neighborhood Hits	39	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

SFRP1_MOUSE
NC score	0.059304 (rank : 56)	θ value	0.21417 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C4U3, O08861, Q8R1J4	Gene names	Sfrp1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1).

SFRP1_HUMAN
NC score	0.058802 (rank : 57)	θ value	0.21417 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N474, O00546, O14779	Gene names	SFRP1, FRP, FRP1, SARP2
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1) (Frizzled- related protein 1) (FRP-1) (Secreted apoptosis-related protein 2) (SARP-2).

PERT_HUMAN
NC score	0.056256 (rank : 58)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	42	Target Neighborhood Hits	221	Shared Neighborhood Hits	27
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

SUSD1_HUMAN
NC score	0.052103 (rank : 59)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	42	Target Neighborhood Hits	285	Shared Neighborhood Hits	22
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

PTC1_HUMAN
NC score	0.051072 (rank : 60)	θ value	0.21417 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q13635, Q13463, Q5VZC0	Gene names	PTCH1, PTCH
Domain Architecture
Description	Protein patched homolog 1 (PTC1) (PTC).

IF39_HUMAN
NC score	0.050874 (rank : 61)	θ value	0.813845 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	187	Shared Neighborhood Hits	2
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

ZCH10_MOUSE
NC score	0.042503 (rank : 62)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	133	Shared Neighborhood Hits	2
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

FETUB_MOUSE
NC score	0.027589 (rank : 63)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXC1	Gene names	Fetub
Domain Architecture
Description	Fetuin-B precursor (IRL685).

NIBA_HUMAN
NC score	0.026308 (rank : 64)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	84	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZQ8, Q5TEM8, Q8TEI5, Q9H593, Q9H9Y8, Q9HCB9	Gene names	C1orf24
Domain Architecture	No domain graphic available
Description	Niban protein.

RIN1_HUMAN
NC score	0.015107 (rank : 65)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q13671, O15010, Q00427, Q96CC8	Gene names	RIN1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1) (Ras inhibitor JC99).

SNTA1_HUMAN
NC score	0.013091 (rank : 66)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	186	Shared Neighborhood Hits	2
SwissProt Accessions	Q13424, Q16438	Gene names	SNTA1, SNT1
Domain Architecture
Description	Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin 1).

LTBP4_MOUSE
NC score	0.011264 (rank : 67)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	607	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

HXA5_MOUSE
NC score	0.007382 (rank : 68)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	338	Shared Neighborhood Hits	2
SwissProt Accessions	P09021, Q91VQ5	Gene names	Hoxa5, Hox-1.3, Hoxa-5
Domain Architecture
Description	Homeobox protein Hox-A5 (Hox-1.3) (M2).

M3K14_MOUSE
NC score	0.002393 (rank : 69)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	889	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WUL6	Gene names	Map3k14, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF- kappa beta-inducing kinase) (Serine/threonine-protein kinase NIK).