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Network neighborhood for query Sequence : FHR4_HUMAN

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FHR4_HUMAN
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FHR4_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	75
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

FHR3_HUMAN
θ value	2.35568e-133 (rank : 2)	NC score	0.984411 (rank : 2)
Query Neighborhood Hits	75	Target Neighborhood Hits	74	Shared Neighborhood Hits	66
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

FHR1_HUMAN
θ value	2.17053e-70 (rank : 3)	NC score	0.949912 (rank : 4)
Query Neighborhood Hits	75	Target Neighborhood Hits	80	Shared Neighborhood Hits	65
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

CFAH_HUMAN
θ value	3.35642e-63 (rank : 4)	NC score	0.904507 (rank : 6)
Query Neighborhood Hits	75	Target Neighborhood Hits	101	Shared Neighborhood Hits	70
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

FHR2_HUMAN
θ value	4.24587e-58 (rank : 5)	NC score	0.952460 (rank : 3)
Query Neighborhood Hits	75	Target Neighborhood Hits	63	Shared Neighborhood Hits	61
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

CFAH_MOUSE
θ value	1.0458e-56 (rank : 6)	NC score	0.892184 (rank : 7)
Query Neighborhood Hits	75	Target Neighborhood Hits	112	Shared Neighborhood Hits	69
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

FHR5_HUMAN
θ value	6.56568e-51 (rank : 7)	NC score	0.922587 (rank : 5)
Query Neighborhood Hits	75	Target Neighborhood Hits	77	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

F13B_MOUSE
θ value	3.37985e-39 (rank : 8)	NC score	0.868122 (rank : 8)
Query Neighborhood Hits	75	Target Neighborhood Hits	93	Shared Neighborhood Hits	67
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

F13B_HUMAN
θ value	4.13158e-37 (rank : 9)	NC score	0.866866 (rank : 9)
Query Neighborhood Hits	75	Target Neighborhood Hits	84	Shared Neighborhood Hits	67
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

APOH_MOUSE
θ value	1.52774e-15 (rank : 10)	NC score	0.729130 (rank : 10)
Query Neighborhood Hits	75	Target Neighborhood Hits	74	Shared Neighborhood Hits	62
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

CSMD3_HUMAN
θ value	2.20605e-14 (rank : 11)	NC score	0.558331 (rank : 27)
Query Neighborhood Hits	75	Target Neighborhood Hits	199	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSMD1_HUMAN
θ value	3.76295e-14 (rank : 12)	NC score	0.547605 (rank : 28)
Query Neighborhood Hits	75	Target Neighborhood Hits	176	Shared Neighborhood Hits	70
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
θ value	1.86753e-13 (rank : 13)	NC score	0.541608 (rank : 30)
Query Neighborhood Hits	75	Target Neighborhood Hits	193	Shared Neighborhood Hits	69
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CR2_MOUSE
θ value	9.26847e-13 (rank : 14)	NC score	0.699261 (rank : 15)
Query Neighborhood Hits	75	Target Neighborhood Hits	101	Shared Neighborhood Hits	68
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

CR1_HUMAN
θ value	6.64225e-11 (rank : 15)	NC score	0.703965 (rank : 12)
Query Neighborhood Hits	75	Target Neighborhood Hits	108	Shared Neighborhood Hits	69
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

CR2_HUMAN
θ value	6.64225e-11 (rank : 16)	NC score	0.700868 (rank : 14)
Query Neighborhood Hits	75	Target Neighborhood Hits	89	Shared Neighborhood Hits	68
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

SUSD4_HUMAN
θ value	1.47974e-10 (rank : 17)	NC score	0.686213 (rank : 18)
Query Neighborhood Hits	75	Target Neighborhood Hits	88	Shared Neighborhood Hits	59
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

SUSD4_MOUSE
θ value	1.9326e-10 (rank : 18)	NC score	0.690636 (rank : 17)
Query Neighborhood Hits	75	Target Neighborhood Hits	122	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

C4BP_MOUSE
θ value	9.59137e-10 (rank : 19)	NC score	0.702823 (rank : 13)
Query Neighborhood Hits	75	Target Neighborhood Hits	91	Shared Neighborhood Hits	69
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

DAF_HUMAN
θ value	8.11959e-09 (rank : 20)	NC score	0.658303 (rank : 22)
Query Neighborhood Hits	75	Target Neighborhood Hits	97	Shared Neighborhood Hits	68
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

C4BP_HUMAN
θ value	1.80886e-08 (rank : 21)	NC score	0.695541 (rank : 16)
Query Neighborhood Hits	75	Target Neighborhood Hits	92	Shared Neighborhood Hits	69
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

APOH_HUMAN
θ value	5.26297e-08 (rank : 22)	NC score	0.709796 (rank : 11)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	63
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

SEZ6L_HUMAN
θ value	3.41135e-07 (rank : 23)	NC score	0.543477 (rank : 29)
Query Neighborhood Hits	75	Target Neighborhood Hits	289	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

ZP3R_MOUSE
θ value	4.45536e-07 (rank : 24)	NC score	0.682226 (rank : 20)
Query Neighborhood Hits	75	Target Neighborhood Hits	81	Shared Neighborhood Hits	66
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

CRRY_MOUSE
θ value	2.21117e-06 (rank : 25)	NC score	0.683153 (rank : 19)
Query Neighborhood Hits	75	Target Neighborhood Hits	84	Shared Neighborhood Hits	67
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

CS1A_MOUSE
θ value	3.77169e-06 (rank : 26)	NC score	0.192707 (rank : 56)
Query Neighborhood Hits	75	Target Neighborhood Hits	360	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

PAP2_HUMAN
θ value	4.92598e-06 (rank : 27)	NC score	0.401258 (rank : 40)
Query Neighborhood Hits	75	Target Neighborhood Hits	106	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

CS1B_MOUSE
θ value	6.43352e-06 (rank : 28)	NC score	0.190782 (rank : 57)
Query Neighborhood Hits	75	Target Neighborhood Hits	361	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

MCP_HUMAN
θ value	1.09739e-05 (rank : 29)	NC score	0.658879 (rank : 21)
Query Neighborhood Hits	75	Target Neighborhood Hits	82	Shared Neighborhood Hits	65
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

SRPX_MOUSE
θ value	1.87187e-05 (rank : 30)	NC score	0.529779 (rank : 31)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

SRPX_HUMAN
θ value	2.44474e-05 (rank : 31)	NC score	0.513817 (rank : 33)
Query Neighborhood Hits	75	Target Neighborhood Hits	69	Shared Neighborhood Hits	51
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

CSMD2_HUMAN
θ value	4.1701e-05 (rank : 32)	NC score	0.518554 (rank : 32)
Query Neighborhood Hits	75	Target Neighborhood Hits	188	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

DAF2_MOUSE
θ value	5.44631e-05 (rank : 33)	NC score	0.633879 (rank : 24)
Query Neighborhood Hits	75	Target Neighborhood Hits	114	Shared Neighborhood Hits	67
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

LYAM2_MOUSE
θ value	0.000121331 (rank : 34)	NC score	0.495475 (rank : 36)
Query Neighborhood Hits	75	Target Neighborhood Hits	420	Shared Neighborhood Hits	70
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

DAF1_MOUSE
θ value	0.00020696 (rank : 35)	NC score	0.623513 (rank : 25)
Query Neighborhood Hits	75	Target Neighborhood Hits	204	Shared Neighborhood Hits	67
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

C1R_HUMAN
θ value	0.000270298 (rank : 36)	NC score	0.170966 (rank : 67)
Query Neighborhood Hits	75	Target Neighborhood Hits	364	Shared Neighborhood Hits	51
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

MCP_MOUSE
θ value	0.00035302 (rank : 37)	NC score	0.616615 (rank : 26)
Query Neighborhood Hits	75	Target Neighborhood Hits	79	Shared Neighborhood Hits	65
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

C1RB_MOUSE
θ value	0.000461057 (rank : 38)	NC score	0.179680 (rank : 63)
Query Neighborhood Hits	75	Target Neighborhood Hits	380	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1RA_MOUSE
θ value	0.000786445 (rank : 39)	NC score	0.181316 (rank : 62)
Query Neighborhood Hits	75	Target Neighborhood Hits	379	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1S_HUMAN
θ value	0.000786445 (rank : 40)	NC score	0.189033 (rank : 58)
Query Neighborhood Hits	75	Target Neighborhood Hits	359	Shared Neighborhood Hits	52
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

C4BB_HUMAN
θ value	0.00228821 (rank : 41)	NC score	0.653837 (rank : 23)
Query Neighborhood Hits	75	Target Neighborhood Hits	77	Shared Neighborhood Hits	59
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

CFAB_MOUSE
θ value	0.00228821 (rank : 42)	NC score	0.326333 (rank : 43)
Query Neighborhood Hits	75	Target Neighborhood Hits	262	Shared Neighborhood Hits	68
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_HUMAN
θ value	0.00298849 (rank : 43)	NC score	0.332466 (rank : 42)
Query Neighborhood Hits	75	Target Neighborhood Hits	251	Shared Neighborhood Hits	67
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

LYAM2_HUMAN
θ value	0.00390308 (rank : 44)	NC score	0.483446 (rank : 37)
Query Neighborhood Hits	75	Target Neighborhood Hits	394	Shared Neighborhood Hits	71
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_MOUSE
θ value	0.00390308 (rank : 45)	NC score	0.499241 (rank : 35)
Query Neighborhood Hits	75	Target Neighborhood Hits	390	Shared Neighborhood Hits	71
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MASP1_HUMAN
θ value	0.00390308 (rank : 46)	NC score	0.174682 (rank : 65)
Query Neighborhood Hits	75	Target Neighborhood Hits	369	Shared Neighborhood Hits	56
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

CSPG3_MOUSE
θ value	0.00509761 (rank : 47)	NC score	0.153709 (rank : 68)
Query Neighborhood Hits	75	Target Neighborhood Hits	657	Shared Neighborhood Hits	50
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

PERT_HUMAN
θ value	0.00665767 (rank : 48)	NC score	0.186304 (rank : 59)
Query Neighborhood Hits	75	Target Neighborhood Hits	221	Shared Neighborhood Hits	52
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

MASP2_MOUSE
θ value	0.00869519 (rank : 49)	NC score	0.205307 (rank : 54)
Query Neighborhood Hits	75	Target Neighborhood Hits	382	Shared Neighborhood Hits	59
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

CSPG2_HUMAN
θ value	0.0113563 (rank : 50)	NC score	0.132385 (rank : 72)
Query Neighborhood Hits	75	Target Neighborhood Hits	681	Shared Neighborhood Hits	43
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

PAPPA_MOUSE
θ value	0.0113563 (rank : 51)	NC score	0.425965 (rank : 39)
Query Neighborhood Hits	75	Target Neighborhood Hits	153	Shared Neighborhood Hits	54
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

CSPG2_MOUSE
θ value	0.0252991 (rank : 52)	NC score	0.133723 (rank : 71)
Query Neighborhood Hits	75	Target Neighborhood Hits	711	Shared Neighborhood Hits	44
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

LYAM3_HUMAN
θ value	0.0563607 (rank : 53)	NC score	0.509243 (rank : 34)
Query Neighborhood Hits	75	Target Neighborhood Hits	378	Shared Neighborhood Hits	69
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MASP1_MOUSE
θ value	0.0961366 (rank : 54)	NC score	0.171935 (rank : 66)
Query Neighborhood Hits	75	Target Neighborhood Hits	364	Shared Neighborhood Hits	52
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

CSPG3_HUMAN
θ value	0.163984 (rank : 55)	NC score	0.137792 (rank : 69)
Query Neighborhood Hits	75	Target Neighborhood Hits	676	Shared Neighborhood Hits	50
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

PAPPA_HUMAN
θ value	0.163984 (rank : 56)	NC score	0.427048 (rank : 38)
Query Neighborhood Hits	75	Target Neighborhood Hits	161	Shared Neighborhood Hits	55
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PGCA_HUMAN
θ value	0.163984 (rank : 57)	NC score	0.121410 (rank : 73)
Query Neighborhood Hits	75	Target Neighborhood Hits	821	Shared Neighborhood Hits	46
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PERT_MOUSE
θ value	0.21417 (rank : 58)	NC score	0.186108 (rank : 60)
Query Neighborhood Hits	75	Target Neighborhood Hits	221	Shared Neighborhood Hits	51
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

GABR1_HUMAN
θ value	0.279714 (rank : 59)	NC score	0.246503 (rank : 52)
Query Neighborhood Hits	75	Target Neighborhood Hits	142	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
θ value	0.279714 (rank : 60)	NC score	0.245641 (rank : 53)
Query Neighborhood Hits	75	Target Neighborhood Hits	139	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

MASP2_HUMAN
θ value	0.279714 (rank : 61)	NC score	0.182179 (rank : 61)
Query Neighborhood Hits	75	Target Neighborhood Hits	364	Shared Neighborhood Hits	54
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

PGCA_MOUSE
θ value	0.279714 (rank : 62)	NC score	0.136670 (rank : 70)
Query Neighborhood Hits	75	Target Neighborhood Hits	643	Shared Neighborhood Hits	44
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

SUSD2_MOUSE
θ value	0.279714 (rank : 63)	NC score	0.340691 (rank : 41)
Query Neighborhood Hits	75	Target Neighborhood Hits	104	Shared Neighborhood Hits	61
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

K0247_HUMAN
θ value	0.813845 (rank : 64)	NC score	0.310502 (rank : 46)
Query Neighborhood Hits	75	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	Q92537	Gene names	KIAA0247
Domain Architecture	No domain graphic available
Description	Protein KIAA0247 precursor.

PCSK5_MOUSE
θ value	1.38821 (rank : 65)	NC score	0.022017 (rank : 128)
Query Neighborhood Hits	75	Target Neighborhood Hits	613	Shared Neighborhood Hits	25
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PGCB_HUMAN
θ value	1.38821 (rank : 66)	NC score	0.118170 (rank : 74)
Query Neighborhood Hits	75	Target Neighborhood Hits	478	Shared Neighborhood Hits	43
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

SUSD2_HUMAN
θ value	1.38821 (rank : 67)	NC score	0.311908 (rank : 45)
Query Neighborhood Hits	75	Target Neighborhood Hits	99	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

FBX25_MOUSE
θ value	2.36792 (rank : 68)	NC score	0.015648 (rank : 129)
Query Neighborhood Hits	75	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D2Y6, Q9D8H3	Gene names	Fbxo25, Fbx25
Domain Architecture	No domain graphic available
Description	F-box only protein 25.

CO6_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.247142 (rank : 51)
Query Neighborhood Hits	75	Target Neighborhood Hits	331	Shared Neighborhood Hits	63
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

PGCB_MOUSE
θ value	4.03905 (rank : 70)	NC score	0.108428 (rank : 83)
Query Neighborhood Hits	75	Target Neighborhood Hits	459	Shared Neighborhood Hits	46
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

HPT_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.117613 (rank : 75)
Query Neighborhood Hits	75	Target Neighborhood Hits	184	Shared Neighborhood Hits	30
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

NELL1_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.014174 (rank : 130)
Query Neighborhood Hits	75	Target Neighborhood Hits	451	Shared Neighborhood Hits	24
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

PCSK5_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.014101 (rank : 131)
Query Neighborhood Hits	75	Target Neighborhood Hits	291	Shared Neighborhood Hits	11
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

VIPR2_HUMAN
θ value	6.88961 (rank : 74)	NC score	0.002722 (rank : 133)
Query Neighborhood Hits	75	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	P41587, Q13053, Q15870	Gene names	VIPR2, VIP2R
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (Helodermin-preferring VIP receptor).

MN1_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.011561 (rank : 132)
Query Neighborhood Hits	75	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

BMP1_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.112292 (rank : 81)
Query Neighborhood Hits	75	Target Neighborhood Hits	233	Shared Neighborhood Hits	23
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.112716 (rank : 78)
Query Neighborhood Hits	75	Target Neighborhood Hits	236	Shared Neighborhood Hits	23
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

CO2_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.313587 (rank : 44)
Query Neighborhood Hits	75	Target Neighborhood Hits	258	Shared Neighborhood Hits	64
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO2_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.253043 (rank : 49)
Query Neighborhood Hits	75	Target Neighborhood Hits	250	Shared Neighborhood Hits	64
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO7_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.247736 (rank : 50)
Query Neighborhood Hits	75	Target Neighborhood Hits	278	Shared Neighborhood Hits	46
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CUBN_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.089017 (rank : 93)
Query Neighborhood Hits	75	Target Neighborhood Hits	482	Shared Neighborhood Hits	32
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.083426 (rank : 101)
Query Neighborhood Hits	75	Target Neighborhood Hits	477	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CUZD1_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.090878 (rank : 92)
Query Neighborhood Hits	75	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUZD1_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.086171 (rank : 99)
Query Neighborhood Hits	75	Target Neighborhood Hits	91	Shared Neighborhood Hits	15
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

DCBD1_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.064343 (rank : 117)
Query Neighborhood Hits	75	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD1_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.085892 (rank : 100)
Query Neighborhood Hits	75	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.069425 (rank : 115)
Query Neighborhood Hits	75	Target Neighborhood Hits	118	Shared Neighborhood Hits	15
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.063305 (rank : 119)
Query Neighborhood Hits	75	Target Neighborhood Hits	113	Shared Neighborhood Hits	15
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DMBT1_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.064083 (rank : 118)
Query Neighborhood Hits	75	Target Neighborhood Hits	152	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DMBT1_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.077699 (rank : 106)
Query Neighborhood Hits	75	Target Neighborhood Hits	134	Shared Neighborhood Hits	15
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

ENTK_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.052616 (rank : 125)
Query Neighborhood Hits	75	Target Neighborhood Hits	310	Shared Neighborhood Hits	19
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ENTK_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.054009 (rank : 124)
Query Neighborhood Hits	75	Target Neighborhood Hits	338	Shared Neighborhood Hits	20
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

GP126_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.059776 (rank : 121)
Query Neighborhood Hits	75	Target Neighborhood Hits	187	Shared Neighborhood Hits	16
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

HPTR_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.066135 (rank : 116)
Query Neighborhood Hits	75	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

HPT_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.070812 (rank : 113)
Query Neighborhood Hits	75	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

IL2RA_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.087695 (rank : 94)
Query Neighborhood Hits	75	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	P01589	Gene names	IL2RA
Domain Architecture
Description	Interleukin-2 receptor alpha chain precursor (IL-2 receptor alpha subunit) (IL-2-RA) (IL2-RA) (p55) (TAC antigen) (CD25 antigen).

IL2RA_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.057318 (rank : 122)
Query Neighborhood Hits	75	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	P01590, Q61731	Gene names	Il2ra, Il2r
Domain Architecture
Description	Interleukin-2 receptor alpha chain precursor (IL-2 receptor alpha subunit) (IL-2-RA) (IL2-RA) (p55) (CD25 antigen).

KREM1_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.071428 (rank : 112)
Query Neighborhood Hits	75	Target Neighborhood Hits	90	Shared Neighborhood Hits	15
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM1_MOUSE
θ value	θ > 10 (rank : 99)	NC score	0.073526 (rank : 110)
Query Neighborhood Hits	75	Target Neighborhood Hits	92	Shared Neighborhood Hits	15
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM2_HUMAN
θ value	θ > 10 (rank : 100)	NC score	0.069711 (rank : 114)
Query Neighborhood Hits	75	Target Neighborhood Hits	93	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KREM2_MOUSE
θ value	θ > 10 (rank : 101)	NC score	0.062981 (rank : 120)
Query Neighborhood Hits	75	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

LRP12_HUMAN
θ value	θ > 10 (rank : 102)	NC score	0.075323 (rank : 108)
Query Neighborhood Hits	75	Target Neighborhood Hits	205	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.075707 (rank : 107)
Query Neighborhood Hits	75	Target Neighborhood Hits	180	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP3_HUMAN
θ value	θ > 10 (rank : 104)	NC score	0.055639 (rank : 123)
Query Neighborhood Hits	75	Target Neighborhood Hits	280	Shared Neighborhood Hits	17
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LYAM1_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.290335 (rank : 47)
Query Neighborhood Hits	75	Target Neighborhood Hits	315	Shared Neighborhood Hits	57
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM1_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.279018 (rank : 48)
Query Neighborhood Hits	75	Target Neighborhood Hits	332	Shared Neighborhood Hits	57
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

MFRP_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.093770 (rank : 91)
Query Neighborhood Hits	75	Target Neighborhood Hits	165	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.098492 (rank : 89)
Query Neighborhood Hits	75	Target Neighborhood Hits	166	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NETO1_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.079821 (rank : 103)
Query Neighborhood Hits	75	Target Neighborhood Hits	110	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.079486 (rank : 104)
Query Neighborhood Hits	75	Target Neighborhood Hits	109	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.074026 (rank : 109)
Query Neighborhood Hits	75	Target Neighborhood Hits	109	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.073364 (rank : 111)
Query Neighborhood Hits	75	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NRP1_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.079057 (rank : 105)
Query Neighborhood Hits	75	Target Neighborhood Hits	119	Shared Neighborhood Hits	15
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.080761 (rank : 102)
Query Neighborhood Hits	75	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.086559 (rank : 98)
Query Neighborhood Hits	75	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.087204 (rank : 96)
Query Neighborhood Hits	75	Target Neighborhood Hits	113	Shared Neighborhood Hits	15
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

PCOC1_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.107794 (rank : 84)
Query Neighborhood Hits	75	Target Neighborhood Hits	146	Shared Neighborhood Hits	16
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 118)	NC score	0.107181 (rank : 85)
Query Neighborhood Hits	75	Target Neighborhood Hits	100	Shared Neighborhood Hits	15
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.101569 (rank : 88)
Query Neighborhood Hits	75	Target Neighborhood Hits	73	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.097169 (rank : 90)
Query Neighborhood Hits	75	Target Neighborhood Hits	73	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PDGFD_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.087354 (rank : 95)
Query Neighborhood Hits	75	Target Neighborhood Hits	74	Shared Neighborhood Hits	15
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

PDGFD_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.087142 (rank : 97)
Query Neighborhood Hits	75	Target Neighborhood Hits	72	Shared Neighborhood Hits	14
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

ST14_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.050061 (rank : 127)
Query Neighborhood Hits	75	Target Neighborhood Hits	409	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ST14_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.051192 (rank : 126)
Query Neighborhood Hits	75	Target Neighborhood Hits	419	Shared Neighborhood Hits	19
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

SUSD1_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.196197 (rank : 55)
Query Neighborhood Hits	75	Target Neighborhood Hits	285	Shared Neighborhood Hits	57
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

SUSD3_HUMAN
θ value	θ > 10 (rank : 126)	NC score	0.108846 (rank : 82)
Query Neighborhood Hits	75	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q96L08, Q49AA6, Q6UXV7	Gene names	SUSD3, UNQ9387/PRO34275
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

SUSD3_MOUSE
θ value	θ > 10 (rank : 127)	NC score	0.175686 (rank : 64)
Query Neighborhood Hits	75	Target Neighborhood Hits	39	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

TLL1_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.112293 (rank : 80)
Query Neighborhood Hits	75	Target Neighborhood Hits	236	Shared Neighborhood Hits	22
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.112566 (rank : 79)
Query Neighborhood Hits	75	Target Neighborhood Hits	237	Shared Neighborhood Hits	23
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 130)	NC score	0.113298 (rank : 77)
Query Neighborhood Hits	75	Target Neighborhood Hits	241	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.114768 (rank : 76)
Query Neighborhood Hits	75	Target Neighborhood Hits	240	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TSG6_HUMAN
θ value	θ > 10 (rank : 132)	NC score	0.106212 (rank : 87)
Query Neighborhood Hits	75	Target Neighborhood Hits	91	Shared Neighborhood Hits	23
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.106731 (rank : 86)
Query Neighborhood Hits	75	Target Neighborhood Hits	91	Shared Neighborhood Hits	23
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

Hits sorted by NC score

FHR4_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	75
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

FHR3_HUMAN
NC score	0.984411 (rank : 2)	θ value	2.35568e-133 (rank : 2)
Query Neighborhood Hits	75	Target Neighborhood Hits	74	Shared Neighborhood Hits	66
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

FHR2_HUMAN
NC score	0.952460 (rank : 3)	θ value	4.24587e-58 (rank : 5)
Query Neighborhood Hits	75	Target Neighborhood Hits	63	Shared Neighborhood Hits	61
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

FHR1_HUMAN
NC score	0.949912 (rank : 4)	θ value	2.17053e-70 (rank : 3)
Query Neighborhood Hits	75	Target Neighborhood Hits	80	Shared Neighborhood Hits	65
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

FHR5_HUMAN
NC score	0.922587 (rank : 5)	θ value	6.56568e-51 (rank : 7)
Query Neighborhood Hits	75	Target Neighborhood Hits	77	Shared Neighborhood Hits	66
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

CFAH_HUMAN
NC score	0.904507 (rank : 6)	θ value	3.35642e-63 (rank : 4)
Query Neighborhood Hits	75	Target Neighborhood Hits	101	Shared Neighborhood Hits	70
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

CFAH_MOUSE
NC score	0.892184 (rank : 7)	θ value	1.0458e-56 (rank : 6)
Query Neighborhood Hits	75	Target Neighborhood Hits	112	Shared Neighborhood Hits	69
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

F13B_MOUSE
NC score	0.868122 (rank : 8)	θ value	3.37985e-39 (rank : 8)
Query Neighborhood Hits	75	Target Neighborhood Hits	93	Shared Neighborhood Hits	67
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

F13B_HUMAN
NC score	0.866866 (rank : 9)	θ value	4.13158e-37 (rank : 9)
Query Neighborhood Hits	75	Target Neighborhood Hits	84	Shared Neighborhood Hits	67
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

APOH_MOUSE
NC score	0.729130 (rank : 10)	θ value	1.52774e-15 (rank : 10)
Query Neighborhood Hits	75	Target Neighborhood Hits	74	Shared Neighborhood Hits	62
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

APOH_HUMAN
NC score	0.709796 (rank : 11)	θ value	5.26297e-08 (rank : 22)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	63
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

CR1_HUMAN
NC score	0.703965 (rank : 12)	θ value	6.64225e-11 (rank : 15)
Query Neighborhood Hits	75	Target Neighborhood Hits	108	Shared Neighborhood Hits	69
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

C4BP_MOUSE
NC score	0.702823 (rank : 13)	θ value	9.59137e-10 (rank : 19)
Query Neighborhood Hits	75	Target Neighborhood Hits	91	Shared Neighborhood Hits	69
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

CR2_HUMAN
NC score	0.700868 (rank : 14)	θ value	6.64225e-11 (rank : 16)
Query Neighborhood Hits	75	Target Neighborhood Hits	89	Shared Neighborhood Hits	68
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

CR2_MOUSE
NC score	0.699261 (rank : 15)	θ value	9.26847e-13 (rank : 14)
Query Neighborhood Hits	75	Target Neighborhood Hits	101	Shared Neighborhood Hits	68
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

C4BP_HUMAN
NC score	0.695541 (rank : 16)	θ value	1.80886e-08 (rank : 21)
Query Neighborhood Hits	75	Target Neighborhood Hits	92	Shared Neighborhood Hits	69
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

SUSD4_MOUSE
NC score	0.690636 (rank : 17)	θ value	1.9326e-10 (rank : 18)
Query Neighborhood Hits	75	Target Neighborhood Hits	122	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

SUSD4_HUMAN
NC score	0.686213 (rank : 18)	θ value	1.47974e-10 (rank : 17)
Query Neighborhood Hits	75	Target Neighborhood Hits	88	Shared Neighborhood Hits	59
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

CRRY_MOUSE
NC score	0.683153 (rank : 19)	θ value	2.21117e-06 (rank : 25)
Query Neighborhood Hits	75	Target Neighborhood Hits	84	Shared Neighborhood Hits	67
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

ZP3R_MOUSE
NC score	0.682226 (rank : 20)	θ value	4.45536e-07 (rank : 24)
Query Neighborhood Hits	75	Target Neighborhood Hits	81	Shared Neighborhood Hits	66
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

MCP_HUMAN
NC score	0.658879 (rank : 21)	θ value	1.09739e-05 (rank : 29)
Query Neighborhood Hits	75	Target Neighborhood Hits	82	Shared Neighborhood Hits	65
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

DAF_HUMAN
NC score	0.658303 (rank : 22)	θ value	8.11959e-09 (rank : 20)
Query Neighborhood Hits	75	Target Neighborhood Hits	97	Shared Neighborhood Hits	68
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

C4BB_HUMAN
NC score	0.653837 (rank : 23)	θ value	0.00228821 (rank : 41)
Query Neighborhood Hits	75	Target Neighborhood Hits	77	Shared Neighborhood Hits	59
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

DAF2_MOUSE
NC score	0.633879 (rank : 24)	θ value	5.44631e-05 (rank : 33)
Query Neighborhood Hits	75	Target Neighborhood Hits	114	Shared Neighborhood Hits	67
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

DAF1_MOUSE
NC score	0.623513 (rank : 25)	θ value	0.00020696 (rank : 35)
Query Neighborhood Hits	75	Target Neighborhood Hits	204	Shared Neighborhood Hits	67
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

MCP_MOUSE
NC score	0.616615 (rank : 26)	θ value	0.00035302 (rank : 37)
Query Neighborhood Hits	75	Target Neighborhood Hits	79	Shared Neighborhood Hits	65
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

CSMD3_HUMAN
NC score	0.558331 (rank : 27)	θ value	2.20605e-14 (rank : 11)
Query Neighborhood Hits	75	Target Neighborhood Hits	199	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSMD1_HUMAN
NC score	0.547605 (rank : 28)	θ value	3.76295e-14 (rank : 12)
Query Neighborhood Hits	75	Target Neighborhood Hits	176	Shared Neighborhood Hits	70
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

SEZ6L_HUMAN
NC score	0.543477 (rank : 29)	θ value	3.41135e-07 (rank : 23)
Query Neighborhood Hits	75	Target Neighborhood Hits	289	Shared Neighborhood Hits	59
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

CSMD1_MOUSE
NC score	0.541608 (rank : 30)	θ value	1.86753e-13 (rank : 13)
Query Neighborhood Hits	75	Target Neighborhood Hits	193	Shared Neighborhood Hits	69
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

SRPX_MOUSE
NC score	0.529779 (rank : 31)	θ value	1.87187e-05 (rank : 30)
Query Neighborhood Hits	75	Target Neighborhood Hits	75	Shared Neighborhood Hits	51
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

CSMD2_HUMAN
NC score	0.518554 (rank : 32)	θ value	4.1701e-05 (rank : 32)
Query Neighborhood Hits	75	Target Neighborhood Hits	188	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

SRPX_HUMAN
NC score	0.513817 (rank : 33)	θ value	2.44474e-05 (rank : 31)
Query Neighborhood Hits	75	Target Neighborhood Hits	69	Shared Neighborhood Hits	51
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

LYAM3_HUMAN
NC score	0.509243 (rank : 34)	θ value	0.0563607 (rank : 53)
Query Neighborhood Hits	75	Target Neighborhood Hits	378	Shared Neighborhood Hits	69
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM3_MOUSE
NC score	0.499241 (rank : 35)	θ value	0.00390308 (rank : 45)
Query Neighborhood Hits	75	Target Neighborhood Hits	390	Shared Neighborhood Hits	71
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM2_MOUSE
NC score	0.495475 (rank : 36)	θ value	0.000121331 (rank : 34)
Query Neighborhood Hits	75	Target Neighborhood Hits	420	Shared Neighborhood Hits	70
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM2_HUMAN
NC score	0.483446 (rank : 37)	θ value	0.00390308 (rank : 44)
Query Neighborhood Hits	75	Target Neighborhood Hits	394	Shared Neighborhood Hits	71
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

PAPPA_HUMAN
NC score	0.427048 (rank : 38)	θ value	0.163984 (rank : 56)
Query Neighborhood Hits	75	Target Neighborhood Hits	161	Shared Neighborhood Hits	55
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_MOUSE
NC score	0.425965 (rank : 39)	θ value	0.0113563 (rank : 51)
Query Neighborhood Hits	75	Target Neighborhood Hits	153	Shared Neighborhood Hits	54
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAP2_HUMAN
NC score	0.401258 (rank : 40)	θ value	4.92598e-06 (rank : 27)
Query Neighborhood Hits	75	Target Neighborhood Hits	106	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

SUSD2_MOUSE
NC score	0.340691 (rank : 41)	θ value	0.279714 (rank : 63)
Query Neighborhood Hits	75	Target Neighborhood Hits	104	Shared Neighborhood Hits	61
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

CFAB_HUMAN
NC score	0.332466 (rank : 42)	θ value	0.00298849 (rank : 43)
Query Neighborhood Hits	75	Target Neighborhood Hits	251	Shared Neighborhood Hits	67
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_MOUSE
NC score	0.326333 (rank : 43)	θ value	0.00228821 (rank : 42)
Query Neighborhood Hits	75	Target Neighborhood Hits	262	Shared Neighborhood Hits	68
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CO2_HUMAN
NC score	0.313587 (rank : 44)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	75	Target Neighborhood Hits	258	Shared Neighborhood Hits	64
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

SUSD2_HUMAN
NC score	0.311908 (rank : 45)	θ value	1.38821 (rank : 67)
Query Neighborhood Hits	75	Target Neighborhood Hits	99	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

K0247_HUMAN
NC score	0.310502 (rank : 46)	θ value	0.813845 (rank : 64)
Query Neighborhood Hits	75	Target Neighborhood Hits	42	Shared Neighborhood Hits	30
SwissProt Accessions	Q92537	Gene names	KIAA0247
Domain Architecture	No domain graphic available
Description	Protein KIAA0247 precursor.

LYAM1_HUMAN
NC score	0.290335 (rank : 47)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	75	Target Neighborhood Hits	315	Shared Neighborhood Hits	57
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM1_MOUSE
NC score	0.279018 (rank : 48)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	75	Target Neighborhood Hits	332	Shared Neighborhood Hits	57
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

CO2_MOUSE
NC score	0.253043 (rank : 49)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	75	Target Neighborhood Hits	250	Shared Neighborhood Hits	64
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CO7_HUMAN
NC score	0.247736 (rank : 50)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	75	Target Neighborhood Hits	278	Shared Neighborhood Hits	46
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CO6_HUMAN
NC score	0.247142 (rank : 51)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	75	Target Neighborhood Hits	331	Shared Neighborhood Hits	63
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

GABR1_HUMAN
NC score	0.246503 (rank : 52)	θ value	0.279714 (rank : 59)
Query Neighborhood Hits	75	Target Neighborhood Hits	142	Shared Neighborhood Hits	44
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
NC score	0.245641 (rank : 53)	θ value	0.279714 (rank : 60)
Query Neighborhood Hits	75	Target Neighborhood Hits	139	Shared Neighborhood Hits	44
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

MASP2_MOUSE
NC score	0.205307 (rank : 54)	θ value	0.00869519 (rank : 49)
Query Neighborhood Hits	75	Target Neighborhood Hits	382	Shared Neighborhood Hits	59
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

SUSD1_HUMAN
NC score	0.196197 (rank : 55)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	75	Target Neighborhood Hits	285	Shared Neighborhood Hits	57
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

CS1A_MOUSE
NC score	0.192707 (rank : 56)	θ value	3.77169e-06 (rank : 26)
Query Neighborhood Hits	75	Target Neighborhood Hits	360	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
NC score	0.190782 (rank : 57)	θ value	6.43352e-06 (rank : 28)
Query Neighborhood Hits	75	Target Neighborhood Hits	361	Shared Neighborhood Hits	54
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

C1S_HUMAN
NC score	0.189033 (rank : 58)	θ value	0.000786445 (rank : 40)
Query Neighborhood Hits	75	Target Neighborhood Hits	359	Shared Neighborhood Hits	52
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

PERT_HUMAN
NC score	0.186304 (rank : 59)	θ value	0.00665767 (rank : 48)
Query Neighborhood Hits	75	Target Neighborhood Hits	221	Shared Neighborhood Hits	52
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_MOUSE
NC score	0.186108 (rank : 60)	θ value	0.21417 (rank : 58)
Query Neighborhood Hits	75	Target Neighborhood Hits	221	Shared Neighborhood Hits	51
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

MASP2_HUMAN
NC score	0.182179 (rank : 61)	θ value	0.279714 (rank : 61)
Query Neighborhood Hits	75	Target Neighborhood Hits	364	Shared Neighborhood Hits	54
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

C1RA_MOUSE
NC score	0.181316 (rank : 62)	θ value	0.000786445 (rank : 39)
Query Neighborhood Hits	75	Target Neighborhood Hits	379	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
NC score	0.179680 (rank : 63)	θ value	0.000461057 (rank : 38)
Query Neighborhood Hits	75	Target Neighborhood Hits	380	Shared Neighborhood Hits	48
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

SUSD3_MOUSE
NC score	0.175686 (rank : 64)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	75	Target Neighborhood Hits	39	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

MASP1_HUMAN
NC score	0.174682 (rank : 65)	θ value	0.00390308 (rank : 46)
Query Neighborhood Hits	75	Target Neighborhood Hits	369	Shared Neighborhood Hits	56
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
NC score	0.171935 (rank : 66)	θ value	0.0961366 (rank : 54)
Query Neighborhood Hits	75	Target Neighborhood Hits	364	Shared Neighborhood Hits	52
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

C1R_HUMAN
NC score	0.170966 (rank : 67)	θ value	0.000270298 (rank : 36)
Query Neighborhood Hits	75	Target Neighborhood Hits	364	Shared Neighborhood Hits	51
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

CSPG3_MOUSE
NC score	0.153709 (rank : 68)	θ value	0.00509761 (rank : 47)
Query Neighborhood Hits	75	Target Neighborhood Hits	657	Shared Neighborhood Hits	50
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_HUMAN
NC score	0.137792 (rank : 69)	θ value	0.163984 (rank : 55)
Query Neighborhood Hits	75	Target Neighborhood Hits	676	Shared Neighborhood Hits	50
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

PGCA_MOUSE
NC score	0.136670 (rank : 70)	θ value	0.279714 (rank : 62)
Query Neighborhood Hits	75	Target Neighborhood Hits	643	Shared Neighborhood Hits	44
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

CSPG2_MOUSE
NC score	0.133723 (rank : 71)	θ value	0.0252991 (rank : 52)
Query Neighborhood Hits	75	Target Neighborhood Hits	711	Shared Neighborhood Hits	44
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG2_HUMAN
NC score	0.132385 (rank : 72)	θ value	0.0113563 (rank : 50)
Query Neighborhood Hits	75	Target Neighborhood Hits	681	Shared Neighborhood Hits	43
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

PGCA_HUMAN
NC score	0.121410 (rank : 73)	θ value	0.163984 (rank : 57)
Query Neighborhood Hits	75	Target Neighborhood Hits	821	Shared Neighborhood Hits	46
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PGCB_HUMAN
NC score	0.118170 (rank : 74)	θ value	1.38821 (rank : 66)
Query Neighborhood Hits	75	Target Neighborhood Hits	478	Shared Neighborhood Hits	43
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

HPT_HUMAN
NC score	0.117613 (rank : 75)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	75	Target Neighborhood Hits	184	Shared Neighborhood Hits	30
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

TLL2_MOUSE
NC score	0.114768 (rank : 76)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	75	Target Neighborhood Hits	240	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_HUMAN
NC score	0.113298 (rank : 77)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	75	Target Neighborhood Hits	241	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

BMP1_MOUSE
NC score	0.112716 (rank : 78)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	75	Target Neighborhood Hits	236	Shared Neighborhood Hits	23
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL1_MOUSE
NC score	0.112566 (rank : 79)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	75	Target Neighborhood Hits	237	Shared Neighborhood Hits	23
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL1_HUMAN
NC score	0.112293 (rank : 80)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	75	Target Neighborhood Hits	236	Shared Neighborhood Hits	22
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

BMP1_HUMAN
NC score	0.112292 (rank : 81)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	75	Target Neighborhood Hits	233	Shared Neighborhood Hits	23
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

SUSD3_HUMAN
NC score	0.108846 (rank : 82)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	75	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q96L08, Q49AA6, Q6UXV7	Gene names	SUSD3, UNQ9387/PRO34275
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

PGCB_MOUSE
NC score	0.108428 (rank : 83)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	75	Target Neighborhood Hits	459	Shared Neighborhood Hits	46
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

PCOC1_HUMAN
NC score	0.107794 (rank : 84)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	75	Target Neighborhood Hits	146	Shared Neighborhood Hits	16
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
NC score	0.107181 (rank : 85)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	75	Target Neighborhood Hits	100	Shared Neighborhood Hits	15
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

TSG6_MOUSE
NC score	0.106731 (rank : 86)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	75	Target Neighborhood Hits	91	Shared Neighborhood Hits	23
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSG6_HUMAN
NC score	0.106212 (rank : 87)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	75	Target Neighborhood Hits	91	Shared Neighborhood Hits	23
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

PCOC2_HUMAN
NC score	0.101569 (rank : 88)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	75	Target Neighborhood Hits	73	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

MFRP_MOUSE
NC score	0.098492 (rank : 89)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	75	Target Neighborhood Hits	166	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

PCOC2_MOUSE
NC score	0.097169 (rank : 90)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	75	Target Neighborhood Hits	73	Shared Neighborhood Hits	15
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

MFRP_HUMAN
NC score	0.093770 (rank : 91)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	75	Target Neighborhood Hits	165	Shared Neighborhood Hits	16
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CUZD1_HUMAN
NC score	0.090878 (rank : 92)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	75	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUBN_HUMAN
NC score	0.089017 (rank : 93)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	75	Target Neighborhood Hits	482	Shared Neighborhood Hits	32
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

IL2RA_HUMAN
NC score	0.087695 (rank : 94)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	75	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	P01589	Gene names	IL2RA
Domain Architecture
Description	Interleukin-2 receptor alpha chain precursor (IL-2 receptor alpha subunit) (IL-2-RA) (IL2-RA) (p55) (TAC antigen) (CD25 antigen).

PDGFD_HUMAN
NC score	0.087354 (rank : 95)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	75	Target Neighborhood Hits	74	Shared Neighborhood Hits	15
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

NRP2_MOUSE
NC score	0.087204 (rank : 96)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	75	Target Neighborhood Hits	113	Shared Neighborhood Hits	15
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

PDGFD_MOUSE
NC score	0.087142 (rank : 97)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	75	Target Neighborhood Hits	72	Shared Neighborhood Hits	14
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

NRP2_HUMAN
NC score	0.086559 (rank : 98)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	75	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

CUZD1_MOUSE
NC score	0.086171 (rank : 99)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	75	Target Neighborhood Hits	91	Shared Neighborhood Hits	15
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

DCBD1_MOUSE
NC score	0.085892 (rank : 100)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	75	Target Neighborhood Hits	89	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

CUBN_MOUSE
NC score	0.083426 (rank : 101)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	75	Target Neighborhood Hits	477	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

NRP1_MOUSE
NC score	0.080761 (rank : 102)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	75	Target Neighborhood Hits	120	Shared Neighborhood Hits	15
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NETO1_HUMAN
NC score	0.079821 (rank : 103)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	75	Target Neighborhood Hits	110	Shared Neighborhood Hits	16
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
NC score	0.079486 (rank : 104)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	75	Target Neighborhood Hits	109	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NRP1_HUMAN
NC score	0.079057 (rank : 105)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	75	Target Neighborhood Hits	119	Shared Neighborhood Hits	15
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

DMBT1_MOUSE
NC score	0.077699 (rank : 106)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	75	Target Neighborhood Hits	134	Shared Neighborhood Hits	15
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

LRP12_MOUSE
NC score	0.075707 (rank : 107)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	75	Target Neighborhood Hits	180	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP12_HUMAN
NC score	0.075323 (rank : 108)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	75	Target Neighborhood Hits	205	Shared Neighborhood Hits	16
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

NETO2_HUMAN
NC score	0.074026 (rank : 109)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	75	Target Neighborhood Hits	109	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

KREM1_MOUSE
NC score	0.073526 (rank : 110)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	75	Target Neighborhood Hits	92	Shared Neighborhood Hits	15
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

NETO2_MOUSE
NC score	0.073364 (rank : 111)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	75	Target Neighborhood Hits	113	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

KREM1_HUMAN
NC score	0.071428 (rank : 112)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	75	Target Neighborhood Hits	90	Shared Neighborhood Hits	15
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

HPT_MOUSE
NC score	0.070812 (rank : 113)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	75	Target Neighborhood Hits	178	Shared Neighborhood Hits	18
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

KREM2_HUMAN
NC score	0.069711 (rank : 114)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	75	Target Neighborhood Hits	93	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

DCBD2_HUMAN
NC score	0.069425 (rank : 115)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	75	Target Neighborhood Hits	118	Shared Neighborhood Hits	15
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

HPTR_HUMAN
NC score	0.066135 (rank : 116)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	75	Target Neighborhood Hits	166	Shared Neighborhood Hits	14
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

DCBD1_HUMAN
NC score	0.064343 (rank : 117)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	75	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DMBT1_HUMAN
NC score	0.064083 (rank : 118)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	75	Target Neighborhood Hits	152	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DCBD2_MOUSE
NC score	0.063305 (rank : 119)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	75	Target Neighborhood Hits	113	Shared Neighborhood Hits	15
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

KREM2_MOUSE
NC score	0.062981 (rank : 120)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	75	Target Neighborhood Hits	90	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

GP126_HUMAN
NC score	0.059776 (rank : 121)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	75	Target Neighborhood Hits	187	Shared Neighborhood Hits	16
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

IL2RA_MOUSE
NC score	0.057318 (rank : 122)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	75	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	P01590, Q61731	Gene names	Il2ra, Il2r
Domain Architecture
Description	Interleukin-2 receptor alpha chain precursor (IL-2 receptor alpha subunit) (IL-2-RA) (IL2-RA) (p55) (CD25 antigen).

LRP3_HUMAN
NC score	0.055639 (rank : 123)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	75	Target Neighborhood Hits	280	Shared Neighborhood Hits	17
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

ENTK_MOUSE
NC score	0.054009 (rank : 124)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	75	Target Neighborhood Hits	338	Shared Neighborhood Hits	20
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ENTK_HUMAN
NC score	0.052616 (rank : 125)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	75	Target Neighborhood Hits	310	Shared Neighborhood Hits	19
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ST14_MOUSE
NC score	0.051192 (rank : 126)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	75	Target Neighborhood Hits	419	Shared Neighborhood Hits	19
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

ST14_HUMAN
NC score	0.050061 (rank : 127)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	75	Target Neighborhood Hits	409	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

PCSK5_MOUSE
NC score	0.022017 (rank : 128)	θ value	1.38821 (rank : 65)
Query Neighborhood Hits	75	Target Neighborhood Hits	613	Shared Neighborhood Hits	25
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

FBX25_MOUSE
NC score	0.015648 (rank : 129)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	75	Target Neighborhood Hits	14	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D2Y6, Q9D8H3	Gene names	Fbxo25, Fbx25
Domain Architecture	No domain graphic available
Description	F-box only protein 25.

NELL1_HUMAN
NC score	0.014174 (rank : 130)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	75	Target Neighborhood Hits	451	Shared Neighborhood Hits	24
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

PCSK5_HUMAN
NC score	0.014101 (rank : 131)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	75	Target Neighborhood Hits	291	Shared Neighborhood Hits	11
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

MN1_HUMAN
NC score	0.011561 (rank : 132)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	75	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	Q10571	Gene names	MN1
Domain Architecture	No domain graphic available
Description	Probable tumor suppressor protein MN1.

VIPR2_HUMAN
NC score	0.002722 (rank : 133)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	75	Target Neighborhood Hits	97	Shared Neighborhood Hits	2
SwissProt Accessions	P41587, Q13053, Q15870	Gene names	VIPR2, VIP2R
Domain Architecture
Description	Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (Helodermin-preferring VIP receptor).