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Network neighborhood for query Sequence : CBPZ_MOUSE

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CBPZ_MOUSE
SwissProt Accessions	Q8R4V4	Gene names	Cpz
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CBPZ_HUMAN
θ value	0 (rank : 1)	NC score	0.995290 (rank : 2)
Query Neighborhood Hits	77	Target Neighborhood Hits	69	Shared Neighborhood Hits	64
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CBPZ_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	77
SwissProt Accessions	Q8R4V4	Gene names	Cpz
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CBPE_MOUSE
θ value	4.77967e-110 (rank : 3)	NC score	0.906554 (rank : 3)
Query Neighborhood Hits	77	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q00493, Q64439	Gene names	Cpe
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

CBPE_HUMAN
θ value	1.39067e-109 (rank : 4)	NC score	0.906497 (rank : 4)
Query Neighborhood Hits	77	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	P16870, Q9UIU9	Gene names	CPE
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

CPXM1_HUMAN
θ value	6.45994e-107 (rank : 5)	NC score	0.806005 (rank : 12)
Query Neighborhood Hits	77	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	Q96SM3, Q6P4G8, Q6UW65, Q9NUB5	Gene names	CPXM1, CPX1, CPXM
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CBPN_MOUSE
θ value	3.54468e-105 (rank : 6)	NC score	0.904431 (rank : 6)
Query Neighborhood Hits	77	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JJN5, Q91WM9	Gene names	Cpn1
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit).

CPXM1_MOUSE
θ value	1.34698e-104 (rank : 7)	NC score	0.811345 (rank : 11)
Query Neighborhood Hits	77	Target Neighborhood Hits	63	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z100, Q99LA3	Gene names	Cpxm1, Cpx1, Cpxm
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CBPN_HUMAN
θ value	2.2976e-104 (rank : 8)	NC score	0.905057 (rank : 5)
Query Neighborhood Hits	77	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	P15169	Gene names	CPN1, ACBP
Domain Architecture
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit) (Lysine carboxypeptidase) (Arginine carboxypeptidase) (Kininase-1) (Serum carboxypeptidase N) (SCPN) (Anaphylatoxin inactivator) (Plasma carboxypeptidase B).

CPXM2_HUMAN
θ value	2.54619e-95 (rank : 9)	NC score	0.783099 (rank : 13)
Query Neighborhood Hits	77	Target Neighborhood Hits	84	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N436	Gene names	CPXM2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CPXM2_MOUSE
θ value	3.1125e-93 (rank : 10)	NC score	0.781493 (rank : 14)
Query Neighborhood Hits	77	Target Neighborhood Hits	58	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D2L5, O54860, Q8VDQ4	Gene names	Cpxm2, Cpx2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CBPD_MOUSE
θ value	2.64101e-84 (rank : 11)	NC score	0.870054 (rank : 10)
Query Neighborhood Hits	77	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	O89001	Gene names	Cpd
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CBPD_HUMAN
θ value	1.31072e-83 (rank : 12)	NC score	0.870277 (rank : 9)
Query Neighborhood Hits	77	Target Neighborhood Hits	53	Shared Neighborhood Hits	28
SwissProt Accessions	O75976, O15377, Q86SH9, Q86XE6	Gene names	CPD
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CBPM_MOUSE
θ value	1.96316e-71 (rank : 13)	NC score	0.886249 (rank : 8)
Query Neighborhood Hits	77	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	Q80V42, Q497S5, Q9CYH8	Gene names	Cpm
Domain Architecture	No domain graphic available
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

CBPM_HUMAN
θ value	4.83544e-70 (rank : 14)	NC score	0.886581 (rank : 7)
Query Neighborhood Hits	77	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	P14384, Q9H2K9	Gene names	CPM
Domain Architecture
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

CORIN_MOUSE
θ value	2.0648e-12 (rank : 15)	NC score	0.147355 (rank : 64)
Query Neighborhood Hits	77	Target Neighborhood Hits	451	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CORIN_HUMAN
θ value	2.98157e-11 (rank : 16)	NC score	0.144987 (rank : 66)
Query Neighborhood Hits	77	Target Neighborhood Hits	453	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CBPA4_HUMAN
θ value	1.133e-10 (rank : 17)	NC score	0.351092 (rank : 45)
Query Neighborhood Hits	77	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UI42, Q86UY9	Gene names	CPA4, CPA3
Domain Architecture
Description	Carboxypeptidase A4 precursor (EC 3.4.17.-) (Carboxypeptidase A3).

SFRP1_HUMAN
θ value	7.34386e-10 (rank : 18)	NC score	0.406978 (rank : 15)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N474, O00546, O14779	Gene names	SFRP1, FRP, FRP1, SARP2
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1) (Frizzled- related protein 1) (FRP-1) (Secreted apoptosis-related protein 2) (SARP-2).

FZD2_HUMAN
θ value	2.79066e-09 (rank : 19)	NC score	0.383379 (rank : 25)
Query Neighborhood Hits	77	Target Neighborhood Hits	57	Shared Neighborhood Hits	39
SwissProt Accessions	Q14332	Gene names	FZD2
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (hFz2) (FzE2).

FZD2_MOUSE
θ value	2.79066e-09 (rank : 20)	NC score	0.383373 (rank : 26)
Query Neighborhood Hits	77	Target Neighborhood Hits	60	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JIP6, Q810M0, Q9JIP5, Q9WUJ2	Gene names	Fzd2, Fzd10
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (mFz2) (mFz10).

FZD7_HUMAN
θ value	3.64472e-09 (rank : 21)	NC score	0.383299 (rank : 27)
Query Neighborhood Hits	77	Target Neighborhood Hits	56	Shared Neighborhood Hits	39
SwissProt Accessions	O75084, O94816, Q96B74	Gene names	FZD7
Domain Architecture
Description	Frizzled-7 precursor (Fz-7) (hFz7) (FzE3).

FZD7_MOUSE
θ value	3.64472e-09 (rank : 22)	NC score	0.383124 (rank : 28)
Query Neighborhood Hits	77	Target Neighborhood Hits	59	Shared Neighborhood Hits	39
SwissProt Accessions	Q61090	Gene names	Fzd7
Domain Architecture	No domain graphic available
Description	Frizzled-7 precursor (Fz-7) (mFz7).

SFRP1_MOUSE
θ value	3.64472e-09 (rank : 23)	NC score	0.405742 (rank : 16)
Query Neighborhood Hits	77	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C4U3, O08861, Q8R1J4	Gene names	Sfrp1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1).

FZD6_HUMAN
θ value	1.38499e-08 (rank : 24)	NC score	0.377344 (rank : 41)
Query Neighborhood Hits	77	Target Neighborhood Hits	84	Shared Neighborhood Hits	39
SwissProt Accessions	O60353, Q6P9C3	Gene names	FZD6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (hFz6).

SFRP5_HUMAN
θ value	1.38499e-08 (rank : 25)	NC score	0.402438 (rank : 17)
Query Neighborhood Hits	77	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T4F7, O14780, Q86TH7	Gene names	SFRP5, FRP1B, SARP3
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5) (Secreted apoptosis-related protein 3) (SARP-3) (Frizzled-related protein 1b) (FRP-1b).

FZD3_HUMAN
θ value	2.36244e-08 (rank : 26)	NC score	0.379160 (rank : 37)
Query Neighborhood Hits	77	Target Neighborhood Hits	74	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NPG1	Gene names	FZD3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (hFz3).

FZD3_MOUSE
θ value	2.36244e-08 (rank : 27)	NC score	0.379343 (rank : 34)
Query Neighborhood Hits	77	Target Neighborhood Hits	75	Shared Neighborhood Hits	39
SwissProt Accessions	Q61086	Gene names	Fzd3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (mFz3).

SFRP5_MOUSE
θ value	2.36244e-08 (rank : 28)	NC score	0.401600 (rank : 18)
Query Neighborhood Hits	77	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WU66, Q8K269	Gene names	Sfrp5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5).

FZD1_HUMAN
θ value	4.0297e-08 (rank : 29)	NC score	0.380574 (rank : 32)
Query Neighborhood Hits	77	Target Neighborhood Hits	62	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UP38, O94815, Q549T8	Gene names	FZD1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (hFz1) (FzE1).

FZD1_MOUSE
θ value	4.0297e-08 (rank : 30)	NC score	0.380873 (rank : 31)
Query Neighborhood Hits	77	Target Neighborhood Hits	63	Shared Neighborhood Hits	39
SwissProt Accessions	O70421, O08974	Gene names	Fzd1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (mFz1).

SFRP3_HUMAN
θ value	5.26297e-08 (rank : 31)	NC score	0.397041 (rank : 19)
Query Neighborhood Hits	77	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q92765, O00181, Q99686	Gene names	FRZB, FIZ, FRE, FRP, FRZB1, SFRP3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

FZD5_HUMAN
θ value	8.97725e-08 (rank : 32)	NC score	0.379888 (rank : 33)
Query Neighborhood Hits	77	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	Q13467, Q53R22	Gene names	FZD5, HFZ5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (hFz5) (FzE5).

FZD6_MOUSE
θ value	8.97725e-08 (rank : 33)	NC score	0.373576 (rank : 42)
Query Neighborhood Hits	77	Target Neighborhood Hits	135	Shared Neighborhood Hits	39
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

CBPA4_MOUSE
θ value	1.17247e-07 (rank : 34)	NC score	0.309138 (rank : 48)
Query Neighborhood Hits	77	Target Neighborhood Hits	35	Shared Neighborhood Hits	27
SwissProt Accessions	Q6P8K8, Q8BMK6, Q9CTE6	Gene names	Cpa4
Domain Architecture	No domain graphic available
Description	Carboxypeptidase A4 precursor (EC 3.4.17.-).

SFRP3_MOUSE
θ value	1.17247e-07 (rank : 35)	NC score	0.396243 (rank : 22)
Query Neighborhood Hits	77	Target Neighborhood Hits	44	Shared Neighborhood Hits	39
SwissProt Accessions	P97401, O09075, O09093, Q91W58	Gene names	Frzb, Fiz, Fre, Frzb1, Sfrp3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

FZD8_HUMAN
θ value	1.53129e-07 (rank : 36)	NC score	0.382880 (rank : 29)
Query Neighborhood Hits	77	Target Neighborhood Hits	88	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H461	Gene names	FZD8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (hFz8).

FZD8_MOUSE
θ value	1.53129e-07 (rank : 37)	NC score	0.381836 (rank : 30)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	39
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

FZD5_MOUSE
θ value	3.41135e-07 (rank : 38)	NC score	0.378690 (rank : 38)
Query Neighborhood Hits	77	Target Neighborhood Hits	70	Shared Neighborhood Hits	39
SwissProt Accessions	Q9EQD0, O08975, Q8BMR2, Q8CHK9	Gene names	Fzd5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (mFz5).

FZD9_HUMAN
θ value	3.41135e-07 (rank : 39)	NC score	0.379243 (rank : 36)
Query Neighborhood Hits	77	Target Neighborhood Hits	63	Shared Neighborhood Hits	39
SwissProt Accessions	O00144	Gene names	FZD9, FZD3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (hFz9) (FzE6).

FZD9_MOUSE
θ value	3.41135e-07 (rank : 40)	NC score	0.378388 (rank : 39)
Query Neighborhood Hits	77	Target Neighborhood Hits	66	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R216, O35494, Q9CX16, Q9R2B3	Gene names	Fzd9, Fzd3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (mFz9) (mFz3).

SFRP2_HUMAN
θ value	4.45536e-07 (rank : 41)	NC score	0.396892 (rank : 21)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	37
SwissProt Accessions	Q96HF1, O14778, Q9HAP5	Gene names	SFRP2, FRP2, SARP1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (Frizzled-related protein 2) (FRP-2).

SFRP2_MOUSE
θ value	4.45536e-07 (rank : 42)	NC score	0.397009 (rank : 20)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	P97299, O08862, O35297	Gene names	Sfrp2, Sarp1, Sdf5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (SDF5 protein).

FZD10_HUMAN
θ value	5.81887e-07 (rank : 43)	NC score	0.379316 (rank : 35)
Query Neighborhood Hits	77	Target Neighborhood Hits	51	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ULW2	Gene names	FZD10
Domain Architecture
Description	Frizzled-10 precursor (Fz-10) (hFz10) (FzE7).

FZD10_MOUSE
θ value	5.81887e-07 (rank : 44)	NC score	0.377538 (rank : 40)
Query Neighborhood Hits	77	Target Neighborhood Hits	56	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BKG4	Gene names	Fzd10, Fz10
Domain Architecture	No domain graphic available
Description	Frizzled-10 precursor (Fz-10).

SFRP4_HUMAN
θ value	1.29631e-06 (rank : 45)	NC score	0.391471 (rank : 24)
Query Neighborhood Hits	77	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q6FHJ7, O14877, Q4G124, Q6FHM0, Q6PD64	Gene names	SFRP4, FRPHE
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 4 precursor (sFRP-4) (Frizzled protein, human endometrium) (FrpHE).

SFRP4_MOUSE
θ value	1.29631e-06 (rank : 46)	NC score	0.391485 (rank : 23)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z1N6, Q91ZX9	Gene names	Sfrp4
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related sequence protein 4 precursor (sFRP-4) (Frizzled-related protein 4) (FRP-4).

FZD4_HUMAN
θ value	1.87187e-05 (rank : 47)	NC score	0.372313 (rank : 43)
Query Neighborhood Hits	77	Target Neighborhood Hits	54	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ULV1, Q6S9E4	Gene names	FZD4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (hFz4) (FzE4).

MFRP_MOUSE
θ value	1.87187e-05 (rank : 48)	NC score	0.215489 (rank : 58)
Query Neighborhood Hits	77	Target Neighborhood Hits	166	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CBPA5_MOUSE
θ value	2.44474e-05 (rank : 49)	NC score	0.259837 (rank : 53)
Query Neighborhood Hits	77	Target Neighborhood Hits	27	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R4H4	Gene names	Cpa5
Domain Architecture
Description	Carboxypeptidase A5 precursor (EC 3.4.17.1).

MFRP_HUMAN
θ value	2.44474e-05 (rank : 50)	NC score	0.213966 (rank : 59)
Query Neighborhood Hits	77	Target Neighborhood Hits	165	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CBPA2_HUMAN
θ value	3.19293e-05 (rank : 51)	NC score	0.285255 (rank : 51)
Query Neighborhood Hits	77	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	P48052, Q96A12, Q96QN3	Gene names	CPA2
Domain Architecture
Description	Carboxypeptidase A2 precursor (EC 3.4.17.15).

FZD4_MOUSE
θ value	3.19293e-05 (rank : 52)	NC score	0.371111 (rank : 44)
Query Neighborhood Hits	77	Target Neighborhood Hits	52	Shared Neighborhood Hits	39
SwissProt Accessions	Q61088	Gene names	Fzd4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (mFz4).

CBPA6_HUMAN
θ value	0.000270298 (rank : 53)	NC score	0.280992 (rank : 52)
Query Neighborhood Hits	77	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N4T0, Q8NEX8, Q8TDE8, Q9NRI9	Gene names	CPA6, CPAH
Domain Architecture
Description	Carboxypeptidase A6 precursor (EC 3.4.17.1) (Carboxypeptidase B).

SMO_HUMAN
θ value	0.000786445 (rank : 54)	NC score	0.319329 (rank : 46)
Query Neighborhood Hits	77	Target Neighborhood Hits	61	Shared Neighborhood Hits	36
SwissProt Accessions	Q99835	Gene names	SMO, SMOH
Domain Architecture
Description	Smoothened homolog precursor (SMO) (Gx protein).

CBPA5_HUMAN
θ value	0.00134147 (rank : 55)	NC score	0.223549 (rank : 56)
Query Neighborhood Hits	77	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WXQ8, Q86SE2, Q86XM3, Q8NA08	Gene names	CPA5
Domain Architecture
Description	Carboxypeptidase A5 precursor (EC 3.4.17.1).

SMO_MOUSE
θ value	0.00134147 (rank : 56)	NC score	0.315235 (rank : 47)
Query Neighborhood Hits	77	Target Neighborhood Hits	61	Shared Neighborhood Hits	36
SwissProt Accessions	P56726	Gene names	Smo, Smoh
Domain Architecture	No domain graphic available
Description	Smoothened homolog precursor (SMO).

CBPA1_MOUSE
θ value	0.0113563 (rank : 57)	NC score	0.192058 (rank : 62)
Query Neighborhood Hits	77	Target Neighborhood Hits	25	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TPZ8	Gene names	Cpa1
Domain Architecture	No domain graphic available
Description	Carboxypeptidase A1 precursor (EC 3.4.17.1).

CBPB2_MOUSE
θ value	0.0113563 (rank : 58)	NC score	0.292802 (rank : 49)
Query Neighborhood Hits	77	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JHH6, Q5EBI3, Q9QZF0	Gene names	Cpb2, Tafi
Domain Architecture	No domain graphic available
Description	Carboxypeptidase B2 precursor (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Thrombin-activable fibrinolysis inhibitor) (TAFI) (Carboxypeptidase R) (CPR).

CBPA1_HUMAN
θ value	0.0148317 (rank : 59)	NC score	0.193063 (rank : 61)
Query Neighborhood Hits	77	Target Neighborhood Hits	31	Shared Neighborhood Hits	21
SwissProt Accessions	P15085, Q9BS67	Gene names	CPA1, CPA
Domain Architecture
Description	Carboxypeptidase A1 precursor (EC 3.4.17.1).

CBPA6_MOUSE
θ value	0.0193708 (rank : 60)	NC score	0.286889 (rank : 50)
Query Neighborhood Hits	77	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	Q5U901, Q8BVD0	Gene names	Cpa6
Domain Architecture	No domain graphic available
Description	Carboxypeptidase A6 precursor (EC 3.4.17.1).

CBPO_HUMAN
θ value	0.0193708 (rank : 61)	NC score	0.203501 (rank : 60)
Query Neighborhood Hits	77	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IVL8, Q2M277, Q7RTW7	Gene names	CPO
Domain Architecture	No domain graphic available
Description	Carboxypeptidase O precursor (EC 3.4.17.-) (CPO).

COIA1_MOUSE
θ value	0.0252991 (rank : 62)	NC score	0.127314 (rank : 68)
Query Neighborhood Hits	77	Target Neighborhood Hits	481	Shared Neighborhood Hits	37
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

CBPA3_MOUSE
θ value	0.0330416 (rank : 63)	NC score	0.227538 (rank : 55)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	P15089	Gene names	Cpa3
Domain Architecture
Description	Mast cell carboxypeptidase A precursor (EC 3.4.17.1) (MC-CPA) (Carboxypeptidase A3).

GPC6_HUMAN
θ value	0.0330416 (rank : 64)	NC score	0.047571 (rank : 90)
Query Neighborhood Hits	77	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y625	Gene names	GPC6
Domain Architecture
Description	Glypican-6 precursor.

GPC6_MOUSE
θ value	0.0330416 (rank : 65)	NC score	0.047499 (rank : 91)
Query Neighborhood Hits	77	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R087	Gene names	Gpc6
Domain Architecture
Description	Glypican-6 precursor.

CBPA3_HUMAN
θ value	0.0961366 (rank : 66)	NC score	0.221668 (rank : 57)
Query Neighborhood Hits	77	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	P15088, Q96E94	Gene names	CPA3
Domain Architecture
Description	Mast cell carboxypeptidase A precursor (EC 3.4.17.1) (MC-CPA) (Carboxypeptidase A3).

GPC4_HUMAN
θ value	0.125558 (rank : 67)	NC score	0.045888 (rank : 92)
Query Neighborhood Hits	77	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	O75487, Q6ZMA6, Q96L43, Q9NU08, Q9UJN1, Q9UPD9	Gene names	GPC4
Domain Architecture
Description	Glypican-4 precursor (K-glypican).

GPC4_MOUSE
θ value	0.125558 (rank : 68)	NC score	0.045849 (rank : 93)
Query Neighborhood Hits	77	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	P51655, Q923C8	Gene names	Gpc4
Domain Architecture
Description	Glypican-4 precursor (K-glypican).

RGS9_MOUSE
θ value	0.21417 (rank : 69)	NC score	0.020174 (rank : 95)
Query Neighborhood Hits	77	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	O54828, Q9Z0S0	Gene names	Rgs9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS9_HUMAN
θ value	0.365318 (rank : 70)	NC score	0.019324 (rank : 96)
Query Neighborhood Hits	77	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	O75916, O75573, Q696R2, Q8TD64, Q8TD65, Q9HC32, Q9HC33	Gene names	RGS9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

ALEX_MOUSE
θ value	1.81305 (rank : 71)	NC score	0.015321 (rank : 97)
Query Neighborhood Hits	77	Target Neighborhood Hits	197	Shared Neighborhood Hits	2
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

SASH1_HUMAN
θ value	1.81305 (rank : 72)	NC score	0.010549 (rank : 98)
Query Neighborhood Hits	77	Target Neighborhood Hits	292	Shared Neighborhood Hits	2
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

GPC2_MOUSE
θ value	2.36792 (rank : 73)	NC score	0.038649 (rank : 94)
Query Neighborhood Hits	77	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BKV1	Gene names	Gpc2
Domain Architecture	No domain graphic available
Description	Glypican-2 precursor.

MMP15_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.001981 (rank : 102)
Query Neighborhood Hits	77	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	O54732	Gene names	Mmp15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP).

PTPRN_HUMAN
θ value	6.88961 (rank : 75)	NC score	0.003347 (rank : 101)
Query Neighborhood Hits	77	Target Neighborhood Hits	156	Shared Neighborhood Hits	3
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

XPO7_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.008487 (rank : 100)
Query Neighborhood Hits	77	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UIA9, O94846, Q6PJK9, Q8NEK7	Gene names	XPO7, KIAA0745, RANBP16
Domain Architecture
Description	Exportin-7 (Exp7) (Ran-binding protein 16).

XPO7_MOUSE
θ value	6.88961 (rank : 77)	NC score	0.008499 (rank : 99)
Query Neighborhood Hits	77	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPK7, Q3TP94, Q80TS9, Q8BSK5, Q8C9M7, Q8CB42, Q8CBL8, Q8CEF5	Gene names	Xpo7, Kiaa0745, Ranbp16
Domain Architecture
Description	Exportin-7 (Exp7) (Ran-binding protein 16).

CBPB1_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.191642 (rank : 63)
Query Neighborhood Hits	77	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	P15086, O60834, Q96BQ8	Gene names	CPB1, CPB, PCPB
Domain Architecture
Description	Carboxypeptidase B precursor (EC 3.4.17.2) (Pancreas-specific protein) (PASP).

CBPB2_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.242519 (rank : 54)
Query Neighborhood Hits	77	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q96IY4, Q15114, Q5T9K1, Q5T9K2, Q9P2Y6	Gene names	CPB2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase B2 precursor (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Thrombin-activable fibrinolysis inhibitor) (TAFI) (Plasma carboxypeptidase B) (pCPB).

CNTP1_HUMAN
θ value	θ > 10 (rank : 80)	NC score	0.056991 (rank : 87)
Query Neighborhood Hits	77	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP1_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.058598 (rank : 86)
Query Neighborhood Hits	77	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CNTP2_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.068444 (rank : 83)
Query Neighborhood Hits	77	Target Neighborhood Hits	199	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
θ value	θ > 10 (rank : 83)	NC score	0.067620 (rank : 84)
Query Neighborhood Hits	77	Target Neighborhood Hits	194	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP3_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.062466 (rank : 85)
Query Neighborhood Hits	77	Target Neighborhood Hits	195	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CNTP4_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.053297 (rank : 89)
Query Neighborhood Hits	77	Target Neighborhood Hits	187	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP4_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.055131 (rank : 88)
Query Neighborhood Hits	77	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

DCBD1_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.091611 (rank : 73)
Query Neighborhood Hits	77	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.092403 (rank : 72)
Query Neighborhood Hits	77	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.096225 (rank : 70)
Query Neighborhood Hits	77	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

EDIL3_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.076359 (rank : 79)
Query Neighborhood Hits	77	Target Neighborhood Hits	292	Shared Neighborhood Hits	4
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.074830 (rank : 80)
Query Neighborhood Hits	77	Target Neighborhood Hits	317	Shared Neighborhood Hits	4
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

FA5_HUMAN
θ value	θ > 10 (rank : 92)	NC score	0.090104 (rank : 75)
Query Neighborhood Hits	77	Target Neighborhood Hits	172	Shared Neighborhood Hits	4
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

FA8_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.089420 (rank : 76)
Query Neighborhood Hits	77	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

FA8_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.090574 (rank : 74)
Query Neighborhood Hits	77	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

MFGM_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.107148 (rank : 69)
Query Neighborhood Hits	77	Target Neighborhood Hits	150	Shared Neighborhood Hits	4
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

MFGM_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.094204 (rank : 71)
Query Neighborhood Hits	77	Target Neighborhood Hits	233	Shared Neighborhood Hits	4
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

NRP1_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.073933 (rank : 81)
Query Neighborhood Hits	77	Target Neighborhood Hits	119	Shared Neighborhood Hits	6
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.070376 (rank : 82)
Query Neighborhood Hits	77	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP2_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.080037 (rank : 77)
Query Neighborhood Hits	77	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.079429 (rank : 78)
Query Neighborhood Hits	77	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

XLRS1_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.144181 (rank : 67)
Query Neighborhood Hits	77	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

XLRS1_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.145821 (rank : 65)
Query Neighborhood Hits	77	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

Hits sorted by NC score

CBPZ_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	77	Target Neighborhood Hits	77	Shared Neighborhood Hits	77
SwissProt Accessions	Q8R4V4	Gene names	Cpz
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CBPZ_HUMAN
NC score	0.995290 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	77	Target Neighborhood Hits	69	Shared Neighborhood Hits	64
SwissProt Accessions	Q66K79, O00520, Q96MX2	Gene names	CPZ
Domain Architecture	No domain graphic available
Description	Carboxypeptidase Z precursor (EC 3.4.17.-) (CPZ).

CBPE_MOUSE
NC score	0.906554 (rank : 3)	θ value	4.77967e-110 (rank : 3)
Query Neighborhood Hits	77	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q00493, Q64439	Gene names	Cpe
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

CBPE_HUMAN
NC score	0.906497 (rank : 4)	θ value	1.39067e-109 (rank : 4)
Query Neighborhood Hits	77	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	P16870, Q9UIU9	Gene names	CPE
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

CBPN_HUMAN
NC score	0.905057 (rank : 5)	θ value	2.2976e-104 (rank : 8)
Query Neighborhood Hits	77	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	P15169	Gene names	CPN1, ACBP
Domain Architecture
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit) (Lysine carboxypeptidase) (Arginine carboxypeptidase) (Kininase-1) (Serum carboxypeptidase N) (SCPN) (Anaphylatoxin inactivator) (Plasma carboxypeptidase B).

CBPN_MOUSE
NC score	0.904431 (rank : 6)	θ value	3.54468e-105 (rank : 6)
Query Neighborhood Hits	77	Target Neighborhood Hits	26	Shared Neighborhood Hits	23
SwissProt Accessions	Q9JJN5, Q91WM9	Gene names	Cpn1
Domain Architecture	No domain graphic available
Description	Carboxypeptidase N catalytic chain precursor (EC 3.4.17.3) (CPN) (Carboxypeptidase N polypeptide 1) (Carboxypeptidase N small subunit).

CBPM_HUMAN
NC score	0.886581 (rank : 7)	θ value	4.83544e-70 (rank : 14)
Query Neighborhood Hits	77	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	P14384, Q9H2K9	Gene names	CPM
Domain Architecture
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

CBPM_MOUSE
NC score	0.886249 (rank : 8)	θ value	1.96316e-71 (rank : 13)
Query Neighborhood Hits	77	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	Q80V42, Q497S5, Q9CYH8	Gene names	Cpm
Domain Architecture	No domain graphic available
Description	Carboxypeptidase M precursor (EC 3.4.17.12) (CPM).

CBPD_HUMAN
NC score	0.870277 (rank : 9)	θ value	1.31072e-83 (rank : 12)
Query Neighborhood Hits	77	Target Neighborhood Hits	53	Shared Neighborhood Hits	28
SwissProt Accessions	O75976, O15377, Q86SH9, Q86XE6	Gene names	CPD
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CBPD_MOUSE
NC score	0.870054 (rank : 10)	θ value	2.64101e-84 (rank : 11)
Query Neighborhood Hits	77	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	O89001	Gene names	Cpd
Domain Architecture
Description	Carboxypeptidase D precursor (EC 3.4.17.22) (Metallocarboxypeptidase D) (gp180).

CPXM1_MOUSE
NC score	0.811345 (rank : 11)	θ value	1.34698e-104 (rank : 7)
Query Neighborhood Hits	77	Target Neighborhood Hits	63	Shared Neighborhood Hits	23
SwissProt Accessions	Q9Z100, Q99LA3	Gene names	Cpxm1, Cpx1, Cpxm
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CPXM1_HUMAN
NC score	0.806005 (rank : 12)	θ value	6.45994e-107 (rank : 5)
Query Neighborhood Hits	77	Target Neighborhood Hits	69	Shared Neighborhood Hits	25
SwissProt Accessions	Q96SM3, Q6P4G8, Q6UW65, Q9NUB5	Gene names	CPXM1, CPX1, CPXM
Domain Architecture
Description	Probable carboxypeptidase X1 precursor (EC 3.4.17.-) (Metallocarboxypeptidase CPX-1).

CPXM2_HUMAN
NC score	0.783099 (rank : 13)	θ value	2.54619e-95 (rank : 9)
Query Neighborhood Hits	77	Target Neighborhood Hits	84	Shared Neighborhood Hits	23
SwissProt Accessions	Q8N436	Gene names	CPXM2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

CPXM2_MOUSE
NC score	0.781493 (rank : 14)	θ value	3.1125e-93 (rank : 10)
Query Neighborhood Hits	77	Target Neighborhood Hits	58	Shared Neighborhood Hits	23
SwissProt Accessions	Q9D2L5, O54860, Q8VDQ4	Gene names	Cpxm2, Cpx2
Domain Architecture
Description	Carboxypeptidase-like protein X2 precursor.

SFRP1_HUMAN
NC score	0.406978 (rank : 15)	θ value	7.34386e-10 (rank : 18)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q8N474, O00546, O14779	Gene names	SFRP1, FRP, FRP1, SARP2
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1) (Frizzled- related protein 1) (FRP-1) (Secreted apoptosis-related protein 2) (SARP-2).

SFRP1_MOUSE
NC score	0.405742 (rank : 16)	θ value	3.64472e-09 (rank : 23)
Query Neighborhood Hits	77	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q8C4U3, O08861, Q8R1J4	Gene names	Sfrp1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 1 precursor (sFRP-1).

SFRP5_HUMAN
NC score	0.402438 (rank : 17)	θ value	1.38499e-08 (rank : 25)
Query Neighborhood Hits	77	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T4F7, O14780, Q86TH7	Gene names	SFRP5, FRP1B, SARP3
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5) (Secreted apoptosis-related protein 3) (SARP-3) (Frizzled-related protein 1b) (FRP-1b).

SFRP5_MOUSE
NC score	0.401600 (rank : 18)	θ value	2.36244e-08 (rank : 28)
Query Neighborhood Hits	77	Target Neighborhood Hits	42	Shared Neighborhood Hits	39
SwissProt Accessions	Q9WU66, Q8K269	Gene names	Sfrp5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 5 precursor (sFRP-5).

SFRP3_HUMAN
NC score	0.397041 (rank : 19)	θ value	5.26297e-08 (rank : 31)
Query Neighborhood Hits	77	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q92765, O00181, Q99686	Gene names	FRZB, FIZ, FRE, FRP, FRZB1, SFRP3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP2_MOUSE
NC score	0.397009 (rank : 20)	θ value	4.45536e-07 (rank : 42)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	P97299, O08862, O35297	Gene names	Sfrp2, Sarp1, Sdf5
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (SDF5 protein).

SFRP2_HUMAN
NC score	0.396892 (rank : 21)	θ value	4.45536e-07 (rank : 41)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	37
SwissProt Accessions	Q96HF1, O14778, Q9HAP5	Gene names	SFRP2, FRP2, SARP1
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 2 precursor (sFRP-2) (Secreted apoptosis-related protein 1) (SARP-1) (Frizzled-related protein 2) (FRP-2).

SFRP3_MOUSE
NC score	0.396243 (rank : 22)	θ value	1.17247e-07 (rank : 35)
Query Neighborhood Hits	77	Target Neighborhood Hits	44	Shared Neighborhood Hits	39
SwissProt Accessions	P97401, O09075, O09093, Q91W58	Gene names	Frzb, Fiz, Fre, Frzb1, Sfrp3
Domain Architecture
Description	Secreted frizzled-related protein 3 precursor (sFRP-3) (Frizzled- related protein 1) (FrzB-1) (Frezzled) (Fritz).

SFRP4_MOUSE
NC score	0.391485 (rank : 23)	θ value	1.29631e-06 (rank : 46)
Query Neighborhood Hits	77	Target Neighborhood Hits	46	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z1N6, Q91ZX9	Gene names	Sfrp4
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related sequence protein 4 precursor (sFRP-4) (Frizzled-related protein 4) (FRP-4).

SFRP4_HUMAN
NC score	0.391471 (rank : 24)	θ value	1.29631e-06 (rank : 45)
Query Neighborhood Hits	77	Target Neighborhood Hits	43	Shared Neighborhood Hits	39
SwissProt Accessions	Q6FHJ7, O14877, Q4G124, Q6FHM0, Q6PD64	Gene names	SFRP4, FRPHE
Domain Architecture	No domain graphic available
Description	Secreted frizzled-related protein 4 precursor (sFRP-4) (Frizzled protein, human endometrium) (FrpHE).

FZD2_HUMAN
NC score	0.383379 (rank : 25)	θ value	2.79066e-09 (rank : 19)
Query Neighborhood Hits	77	Target Neighborhood Hits	57	Shared Neighborhood Hits	39
SwissProt Accessions	Q14332	Gene names	FZD2
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (hFz2) (FzE2).

FZD2_MOUSE
NC score	0.383373 (rank : 26)	θ value	2.79066e-09 (rank : 20)
Query Neighborhood Hits	77	Target Neighborhood Hits	60	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JIP6, Q810M0, Q9JIP5, Q9WUJ2	Gene names	Fzd2, Fzd10
Domain Architecture
Description	Frizzled-2 precursor (Fz-2) (mFz2) (mFz10).

FZD7_HUMAN
NC score	0.383299 (rank : 27)	θ value	3.64472e-09 (rank : 21)
Query Neighborhood Hits	77	Target Neighborhood Hits	56	Shared Neighborhood Hits	39
SwissProt Accessions	O75084, O94816, Q96B74	Gene names	FZD7
Domain Architecture
Description	Frizzled-7 precursor (Fz-7) (hFz7) (FzE3).

FZD7_MOUSE
NC score	0.383124 (rank : 28)	θ value	3.64472e-09 (rank : 22)
Query Neighborhood Hits	77	Target Neighborhood Hits	59	Shared Neighborhood Hits	39
SwissProt Accessions	Q61090	Gene names	Fzd7
Domain Architecture	No domain graphic available
Description	Frizzled-7 precursor (Fz-7) (mFz7).

FZD8_HUMAN
NC score	0.382880 (rank : 29)	θ value	1.53129e-07 (rank : 36)
Query Neighborhood Hits	77	Target Neighborhood Hits	88	Shared Neighborhood Hits	39
SwissProt Accessions	Q9H461	Gene names	FZD8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (hFz8).

FZD8_MOUSE
NC score	0.381836 (rank : 30)	θ value	1.53129e-07 (rank : 37)
Query Neighborhood Hits	77	Target Neighborhood Hits	89	Shared Neighborhood Hits	39
SwissProt Accessions	Q61091	Gene names	Fzd8
Domain Architecture
Description	Frizzled-8 precursor (Fz-8) (mFz8).

FZD1_MOUSE
NC score	0.380873 (rank : 31)	θ value	4.0297e-08 (rank : 30)
Query Neighborhood Hits	77	Target Neighborhood Hits	63	Shared Neighborhood Hits	39
SwissProt Accessions	O70421, O08974	Gene names	Fzd1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (mFz1).

FZD1_HUMAN
NC score	0.380574 (rank : 32)	θ value	4.0297e-08 (rank : 29)
Query Neighborhood Hits	77	Target Neighborhood Hits	62	Shared Neighborhood Hits	39
SwissProt Accessions	Q9UP38, O94815, Q549T8	Gene names	FZD1
Domain Architecture
Description	Frizzled-1 precursor (Fz-1) (hFz1) (FzE1).

FZD5_HUMAN
NC score	0.379888 (rank : 33)	θ value	8.97725e-08 (rank : 32)
Query Neighborhood Hits	77	Target Neighborhood Hits	71	Shared Neighborhood Hits	39
SwissProt Accessions	Q13467, Q53R22	Gene names	FZD5, HFZ5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (hFz5) (FzE5).

FZD3_MOUSE
NC score	0.379343 (rank : 34)	θ value	2.36244e-08 (rank : 27)
Query Neighborhood Hits	77	Target Neighborhood Hits	75	Shared Neighborhood Hits	39
SwissProt Accessions	Q61086	Gene names	Fzd3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (mFz3).

FZD10_HUMAN
NC score	0.379316 (rank : 35)	θ value	5.81887e-07 (rank : 43)
Query Neighborhood Hits	77	Target Neighborhood Hits	51	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ULW2	Gene names	FZD10
Domain Architecture
Description	Frizzled-10 precursor (Fz-10) (hFz10) (FzE7).

FZD9_HUMAN
NC score	0.379243 (rank : 36)	θ value	3.41135e-07 (rank : 39)
Query Neighborhood Hits	77	Target Neighborhood Hits	63	Shared Neighborhood Hits	39
SwissProt Accessions	O00144	Gene names	FZD9, FZD3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (hFz9) (FzE6).

FZD3_HUMAN
NC score	0.379160 (rank : 37)	θ value	2.36244e-08 (rank : 26)
Query Neighborhood Hits	77	Target Neighborhood Hits	74	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NPG1	Gene names	FZD3
Domain Architecture
Description	Frizzled-3 precursor (Fz-3) (hFz3).

FZD5_MOUSE
NC score	0.378690 (rank : 38)	θ value	3.41135e-07 (rank : 38)
Query Neighborhood Hits	77	Target Neighborhood Hits	70	Shared Neighborhood Hits	39
SwissProt Accessions	Q9EQD0, O08975, Q8BMR2, Q8CHK9	Gene names	Fzd5
Domain Architecture
Description	Frizzled-5 precursor (Fz-5) (mFz5).

FZD9_MOUSE
NC score	0.378388 (rank : 39)	θ value	3.41135e-07 (rank : 40)
Query Neighborhood Hits	77	Target Neighborhood Hits	66	Shared Neighborhood Hits	39
SwissProt Accessions	Q9R216, O35494, Q9CX16, Q9R2B3	Gene names	Fzd9, Fzd3
Domain Architecture
Description	Frizzled-9 precursor (Fz-9) (mFz9) (mFz3).

FZD10_MOUSE
NC score	0.377538 (rank : 40)	θ value	5.81887e-07 (rank : 44)
Query Neighborhood Hits	77	Target Neighborhood Hits	56	Shared Neighborhood Hits	39
SwissProt Accessions	Q8BKG4	Gene names	Fzd10, Fz10
Domain Architecture	No domain graphic available
Description	Frizzled-10 precursor (Fz-10).

FZD6_HUMAN
NC score	0.377344 (rank : 41)	θ value	1.38499e-08 (rank : 24)
Query Neighborhood Hits	77	Target Neighborhood Hits	84	Shared Neighborhood Hits	39
SwissProt Accessions	O60353, Q6P9C3	Gene names	FZD6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (hFz6).

FZD6_MOUSE
NC score	0.373576 (rank : 42)	θ value	8.97725e-08 (rank : 33)
Query Neighborhood Hits	77	Target Neighborhood Hits	135	Shared Neighborhood Hits	39
SwissProt Accessions	Q61089	Gene names	Fzd6
Domain Architecture
Description	Frizzled-6 precursor (Fz-6) (mFz6).

FZD4_HUMAN
NC score	0.372313 (rank : 43)	θ value	1.87187e-05 (rank : 47)
Query Neighborhood Hits	77	Target Neighborhood Hits	54	Shared Neighborhood Hits	39
SwissProt Accessions	Q9ULV1, Q6S9E4	Gene names	FZD4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (hFz4) (FzE4).

FZD4_MOUSE
NC score	0.371111 (rank : 44)	θ value	3.19293e-05 (rank : 52)
Query Neighborhood Hits	77	Target Neighborhood Hits	52	Shared Neighborhood Hits	39
SwissProt Accessions	Q61088	Gene names	Fzd4
Domain Architecture
Description	Frizzled-4 precursor (Fz-4) (mFz4).

CBPA4_HUMAN
NC score	0.351092 (rank : 45)	θ value	1.133e-10 (rank : 17)
Query Neighborhood Hits	77	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UI42, Q86UY9	Gene names	CPA4, CPA3
Domain Architecture
Description	Carboxypeptidase A4 precursor (EC 3.4.17.-) (Carboxypeptidase A3).

SMO_HUMAN
NC score	0.319329 (rank : 46)	θ value	0.000786445 (rank : 54)
Query Neighborhood Hits	77	Target Neighborhood Hits	61	Shared Neighborhood Hits	36
SwissProt Accessions	Q99835	Gene names	SMO, SMOH
Domain Architecture
Description	Smoothened homolog precursor (SMO) (Gx protein).

SMO_MOUSE
NC score	0.315235 (rank : 47)	θ value	0.00134147 (rank : 56)
Query Neighborhood Hits	77	Target Neighborhood Hits	61	Shared Neighborhood Hits	36
SwissProt Accessions	P56726	Gene names	Smo, Smoh
Domain Architecture	No domain graphic available
Description	Smoothened homolog precursor (SMO).

CBPA4_MOUSE
NC score	0.309138 (rank : 48)	θ value	1.17247e-07 (rank : 34)
Query Neighborhood Hits	77	Target Neighborhood Hits	35	Shared Neighborhood Hits	27
SwissProt Accessions	Q6P8K8, Q8BMK6, Q9CTE6	Gene names	Cpa4
Domain Architecture	No domain graphic available
Description	Carboxypeptidase A4 precursor (EC 3.4.17.-).

CBPB2_MOUSE
NC score	0.292802 (rank : 49)	θ value	0.0113563 (rank : 58)
Query Neighborhood Hits	77	Target Neighborhood Hits	36	Shared Neighborhood Hits	27
SwissProt Accessions	Q9JHH6, Q5EBI3, Q9QZF0	Gene names	Cpb2, Tafi
Domain Architecture	No domain graphic available
Description	Carboxypeptidase B2 precursor (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Thrombin-activable fibrinolysis inhibitor) (TAFI) (Carboxypeptidase R) (CPR).

CBPA6_MOUSE
NC score	0.286889 (rank : 50)	θ value	0.0193708 (rank : 60)
Query Neighborhood Hits	77	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	Q5U901, Q8BVD0	Gene names	Cpa6
Domain Architecture	No domain graphic available
Description	Carboxypeptidase A6 precursor (EC 3.4.17.1).

CBPA2_HUMAN
NC score	0.285255 (rank : 51)	θ value	3.19293e-05 (rank : 51)
Query Neighborhood Hits	77	Target Neighborhood Hits	33	Shared Neighborhood Hits	27
SwissProt Accessions	P48052, Q96A12, Q96QN3	Gene names	CPA2
Domain Architecture
Description	Carboxypeptidase A2 precursor (EC 3.4.17.15).

CBPA6_HUMAN
NC score	0.280992 (rank : 52)	θ value	0.000270298 (rank : 53)
Query Neighborhood Hits	77	Target Neighborhood Hits	31	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N4T0, Q8NEX8, Q8TDE8, Q9NRI9	Gene names	CPA6, CPAH
Domain Architecture
Description	Carboxypeptidase A6 precursor (EC 3.4.17.1) (Carboxypeptidase B).

CBPA5_MOUSE
NC score	0.259837 (rank : 53)	θ value	2.44474e-05 (rank : 49)
Query Neighborhood Hits	77	Target Neighborhood Hits	27	Shared Neighborhood Hits	23
SwissProt Accessions	Q8R4H4	Gene names	Cpa5
Domain Architecture
Description	Carboxypeptidase A5 precursor (EC 3.4.17.1).

CBPB2_HUMAN
NC score	0.242519 (rank : 54)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	77	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	Q96IY4, Q15114, Q5T9K1, Q5T9K2, Q9P2Y6	Gene names	CPB2
Domain Architecture	No domain graphic available
Description	Carboxypeptidase B2 precursor (EC 3.4.17.20) (Carboxypeptidase U) (CPU) (Thrombin-activable fibrinolysis inhibitor) (TAFI) (Plasma carboxypeptidase B) (pCPB).

CBPA3_MOUSE
NC score	0.227538 (rank : 55)	θ value	0.0330416 (rank : 63)
Query Neighborhood Hits	77	Target Neighborhood Hits	47	Shared Neighborhood Hits	27
SwissProt Accessions	P15089	Gene names	Cpa3
Domain Architecture
Description	Mast cell carboxypeptidase A precursor (EC 3.4.17.1) (MC-CPA) (Carboxypeptidase A3).

CBPA5_HUMAN
NC score	0.223549 (rank : 56)	θ value	0.00134147 (rank : 55)
Query Neighborhood Hits	77	Target Neighborhood Hits	28	Shared Neighborhood Hits	21
SwissProt Accessions	Q8WXQ8, Q86SE2, Q86XM3, Q8NA08	Gene names	CPA5
Domain Architecture
Description	Carboxypeptidase A5 precursor (EC 3.4.17.1).

CBPA3_HUMAN
NC score	0.221668 (rank : 57)	θ value	0.0961366 (rank : 66)
Query Neighborhood Hits	77	Target Neighborhood Hits	41	Shared Neighborhood Hits	27
SwissProt Accessions	P15088, Q96E94	Gene names	CPA3
Domain Architecture
Description	Mast cell carboxypeptidase A precursor (EC 3.4.17.1) (MC-CPA) (Carboxypeptidase A3).

MFRP_MOUSE
NC score	0.215489 (rank : 58)	θ value	1.87187e-05 (rank : 48)
Query Neighborhood Hits	77	Target Neighborhood Hits	166	Shared Neighborhood Hits	39
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_HUMAN
NC score	0.213966 (rank : 59)	θ value	2.44474e-05 (rank : 50)
Query Neighborhood Hits	77	Target Neighborhood Hits	165	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CBPO_HUMAN
NC score	0.203501 (rank : 60)	θ value	0.0193708 (rank : 61)
Query Neighborhood Hits	77	Target Neighborhood Hits	30	Shared Neighborhood Hits	23
SwissProt Accessions	Q8IVL8, Q2M277, Q7RTW7	Gene names	CPO
Domain Architecture	No domain graphic available
Description	Carboxypeptidase O precursor (EC 3.4.17.-) (CPO).

CBPA1_HUMAN
NC score	0.193063 (rank : 61)	θ value	0.0148317 (rank : 59)
Query Neighborhood Hits	77	Target Neighborhood Hits	31	Shared Neighborhood Hits	21
SwissProt Accessions	P15085, Q9BS67	Gene names	CPA1, CPA
Domain Architecture
Description	Carboxypeptidase A1 precursor (EC 3.4.17.1).

CBPA1_MOUSE
NC score	0.192058 (rank : 62)	θ value	0.0113563 (rank : 57)
Query Neighborhood Hits	77	Target Neighborhood Hits	25	Shared Neighborhood Hits	21
SwissProt Accessions	Q7TPZ8	Gene names	Cpa1
Domain Architecture	No domain graphic available
Description	Carboxypeptidase A1 precursor (EC 3.4.17.1).

CBPB1_HUMAN
NC score	0.191642 (rank : 63)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	77	Target Neighborhood Hits	26	Shared Neighborhood Hits	22
SwissProt Accessions	P15086, O60834, Q96BQ8	Gene names	CPB1, CPB, PCPB
Domain Architecture
Description	Carboxypeptidase B precursor (EC 3.4.17.2) (Pancreas-specific protein) (PASP).

CORIN_MOUSE
NC score	0.147355 (rank : 64)	θ value	2.0648e-12 (rank : 15)
Query Neighborhood Hits	77	Target Neighborhood Hits	451	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

XLRS1_MOUSE
NC score	0.145821 (rank : 65)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	77	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z1L4	Gene names	Rs1, Rs1h, Xlrs1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein homolog).

CORIN_HUMAN
NC score	0.144987 (rank : 66)	θ value	2.98157e-11 (rank : 16)
Query Neighborhood Hits	77	Target Neighborhood Hits	453	Shared Neighborhood Hits	39
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

XLRS1_HUMAN
NC score	0.144181 (rank : 67)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	77	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	O15537	Gene names	RS1, XLRS1
Domain Architecture
Description	Retinoschisin precursor (X-linked juvenile retinoschisis protein).

COIA1_MOUSE
NC score	0.127314 (rank : 68)	θ value	0.0252991 (rank : 62)
Query Neighborhood Hits	77	Target Neighborhood Hits	481	Shared Neighborhood Hits	37
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

MFGM_HUMAN
NC score	0.107148 (rank : 69)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	77	Target Neighborhood Hits	150	Shared Neighborhood Hits	4
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

DCBD2_MOUSE
NC score	0.096225 (rank : 70)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	77	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

MFGM_MOUSE
NC score	0.094204 (rank : 71)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	77	Target Neighborhood Hits	233	Shared Neighborhood Hits	4
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

DCBD2_HUMAN
NC score	0.092403 (rank : 72)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	77	Target Neighborhood Hits	118	Shared Neighborhood Hits	6
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD1_HUMAN
NC score	0.091611 (rank : 73)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	77	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

FA8_MOUSE
NC score	0.090574 (rank : 74)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	77	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

FA5_HUMAN
NC score	0.090104 (rank : 75)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	77	Target Neighborhood Hits	172	Shared Neighborhood Hits	4
SwissProt Accessions	P12259, Q14285, Q6UPU6	Gene names	F5
Domain Architecture
Description	Coagulation factor V precursor (Activated protein C cofactor) [Contains: Coagulation factor V heavy chain; Coagulation factor V light chain].

FA8_HUMAN
NC score	0.089420 (rank : 76)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	77	Target Neighborhood Hits	112	Shared Neighborhood Hits	4
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

NRP2_HUMAN
NC score	0.080037 (rank : 77)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	77	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRP2_MOUSE
NC score	0.079429 (rank : 78)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	77	Target Neighborhood Hits	113	Shared Neighborhood Hits	6
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

EDIL3_HUMAN
NC score	0.076359 (rank : 79)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	77	Target Neighborhood Hits	292	Shared Neighborhood Hits	4
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

EDIL3_MOUSE
NC score	0.074830 (rank : 80)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	77	Target Neighborhood Hits	317	Shared Neighborhood Hits	4
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

NRP1_HUMAN
NC score	0.073933 (rank : 81)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	77	Target Neighborhood Hits	119	Shared Neighborhood Hits	6
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

NRP1_MOUSE
NC score	0.070376 (rank : 82)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	77	Target Neighborhood Hits	120	Shared Neighborhood Hits	6
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

CNTP2_HUMAN
NC score	0.068444 (rank : 83)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	77	Target Neighborhood Hits	199	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
NC score	0.067620 (rank : 84)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	77	Target Neighborhood Hits	194	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP3_HUMAN
NC score	0.062466 (rank : 85)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	77	Target Neighborhood Hits	195	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

CNTP1_MOUSE
NC score	0.058598 (rank : 86)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	77	Target Neighborhood Hits	183	Shared Neighborhood Hits	4
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CNTP1_HUMAN
NC score	0.056991 (rank : 87)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	77	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP4_MOUSE
NC score	0.055131 (rank : 88)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	77	Target Neighborhood Hits	193	Shared Neighborhood Hits	4
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP4_HUMAN
NC score	0.053297 (rank : 89)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	77	Target Neighborhood Hits	187	Shared Neighborhood Hits	4
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

GPC6_HUMAN
NC score	0.047571 (rank : 90)	θ value	0.0330416 (rank : 64)
Query Neighborhood Hits	77	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y625	Gene names	GPC6
Domain Architecture
Description	Glypican-6 precursor.

GPC6_MOUSE
NC score	0.047499 (rank : 91)	θ value	0.0330416 (rank : 65)
Query Neighborhood Hits	77	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R087	Gene names	Gpc6
Domain Architecture
Description	Glypican-6 precursor.

GPC4_HUMAN
NC score	0.045888 (rank : 92)	θ value	0.125558 (rank : 67)
Query Neighborhood Hits	77	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	O75487, Q6ZMA6, Q96L43, Q9NU08, Q9UJN1, Q9UPD9	Gene names	GPC4
Domain Architecture
Description	Glypican-4 precursor (K-glypican).

GPC4_MOUSE
NC score	0.045849 (rank : 93)	θ value	0.125558 (rank : 68)
Query Neighborhood Hits	77	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	P51655, Q923C8	Gene names	Gpc4
Domain Architecture
Description	Glypican-4 precursor (K-glypican).

GPC2_MOUSE
NC score	0.038649 (rank : 94)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	77	Target Neighborhood Hits	18	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BKV1	Gene names	Gpc2
Domain Architecture	No domain graphic available
Description	Glypican-2 precursor.

RGS9_MOUSE
NC score	0.020174 (rank : 95)	θ value	0.21417 (rank : 69)
Query Neighborhood Hits	77	Target Neighborhood Hits	65	Shared Neighborhood Hits	3
SwissProt Accessions	O54828, Q9Z0S0	Gene names	Rgs9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

RGS9_HUMAN
NC score	0.019324 (rank : 96)	θ value	0.365318 (rank : 70)
Query Neighborhood Hits	77	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	O75916, O75573, Q696R2, Q8TD64, Q8TD65, Q9HC32, Q9HC33	Gene names	RGS9
Domain Architecture
Description	Regulator of G-protein signaling 9 (RGS9).

ALEX_MOUSE
NC score	0.015321 (rank : 97)	θ value	1.81305 (rank : 71)
Query Neighborhood Hits	77	Target Neighborhood Hits	197	Shared Neighborhood Hits	2
SwissProt Accessions	Q6R0H6, Q8BIR3	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Protein ALEX (Alternative gene product encoded by XL-exon).

SASH1_HUMAN
NC score	0.010549 (rank : 98)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	77	Target Neighborhood Hits	292	Shared Neighborhood Hits	2
SwissProt Accessions	O94885, Q8TAI0, Q9H7R7	Gene names	SASH1, KIAA0790, PEPE1
Domain Architecture
Description	SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat- containing protein).

XPO7_MOUSE
NC score	0.008499 (rank : 99)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	77	Target Neighborhood Hits	22	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EPK7, Q3TP94, Q80TS9, Q8BSK5, Q8C9M7, Q8CB42, Q8CBL8, Q8CEF5	Gene names	Xpo7, Kiaa0745, Ranbp16
Domain Architecture
Description	Exportin-7 (Exp7) (Ran-binding protein 16).

XPO7_HUMAN
NC score	0.008487 (rank : 100)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	77	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UIA9, O94846, Q6PJK9, Q8NEK7	Gene names	XPO7, KIAA0745, RANBP16
Domain Architecture
Description	Exportin-7 (Exp7) (Ran-binding protein 16).

PTPRN_HUMAN
NC score	0.003347 (rank : 101)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	77	Target Neighborhood Hits	156	Shared Neighborhood Hits	3
SwissProt Accessions	Q16849, Q08319	Gene names	PTPRN, ICA3, ICA512
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase-like N precursor (R-PTP-N) (PTP IA-2) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3).

MMP15_MOUSE
NC score	0.001981 (rank : 102)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	77	Target Neighborhood Hits	102	Shared Neighborhood Hits	2
SwissProt Accessions	O54732	Gene names	Mmp15
Domain Architecture
Description	Matrix metalloproteinase-15 precursor (EC 3.4.24.-) (MMP-15) (Membrane-type matrix metalloproteinase 2) (MT-MMP 2) (MTMMP2) (Membrane-type-2 matrix metalloproteinase) (MT2-MMP) (MT2MMP).