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Network neighborhood for query Sequence : TERF2_HUMAN

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TERF2_HUMAN
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TERF2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	102	Target Neighborhood Hits	102	Shared Neighborhood Hits	102
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

TERF2_MOUSE
θ value	0 (rank : 2)	NC score	0.950140 (rank : 2)
Query Neighborhood Hits	102	Target Neighborhood Hits	128	Shared Neighborhood Hits	37
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

TERF1_HUMAN
θ value	6.38894e-30 (rank : 3)	NC score	0.729966 (rank : 3)
Query Neighborhood Hits	102	Target Neighborhood Hits	83	Shared Neighborhood Hits	22
SwissProt Accessions	P54274, Q15553, Q93029	Gene names	TERF1, PIN2, TRF, TRF1
Domain Architecture
Description	Telomeric repeat-binding factor 1 (TTAGGG repeat-binding factor 1) (NIMA-interacting protein 2) (Telomeric protein Pin2/TRF1).

TERF1_MOUSE
θ value	5.79196e-23 (rank : 4)	NC score	0.717232 (rank : 4)
Query Neighborhood Hits	102	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	P70371, Q9CY71	Gene names	Terf1, Trf1
Domain Architecture
Description	Telomeric repeat-binding factor 1 (TTAGGG repeat-binding factor 1).

MDC1_HUMAN
θ value	0.00134147 (rank : 5)	NC score	0.083255 (rank : 18)
Query Neighborhood Hits	102	Target Neighborhood Hits	1446	Shared Neighborhood Hits	52
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MYBB_HUMAN
θ value	0.00869519 (rank : 6)	NC score	0.208608 (rank : 5)
Query Neighborhood Hits	102	Target Neighborhood Hits	78	Shared Neighborhood Hits	22
SwissProt Accessions	P10244	Gene names	MYBL2, BMYB
Domain Architecture
Description	Myb-related protein B (B-Myb).

TOP2B_MOUSE
θ value	0.00869519 (rank : 7)	NC score	0.087293 (rank : 17)
Query Neighborhood Hits	102	Target Neighborhood Hits	80	Shared Neighborhood Hits	5
SwissProt Accessions	Q64511, Q7TQG4	Gene names	Top2b
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

DNM3A_HUMAN
θ value	0.0252991 (rank : 8)	NC score	0.067802 (rank : 24)
Query Neighborhood Hits	102	Target Neighborhood Hits	104	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

MYBB_MOUSE
θ value	0.0252991 (rank : 9)	NC score	0.201467 (rank : 6)
Query Neighborhood Hits	102	Target Neighborhood Hits	73	Shared Neighborhood Hits	22
SwissProt Accessions	P48972	Gene names	Mybl2, Bmyb
Domain Architecture
Description	Myb-related protein B (B-Myb).

SNPC4_HUMAN
θ value	0.0431538 (rank : 10)	NC score	0.167112 (rank : 9)
Query Neighborhood Hits	102	Target Neighborhood Hits	589	Shared Neighborhood Hits	36
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

BAT2_MOUSE
θ value	0.0961366 (rank : 11)	NC score	0.098599 (rank : 13)
Query Neighborhood Hits	102	Target Neighborhood Hits	947	Shared Neighborhood Hits	37
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

MYB_HUMAN
θ value	0.0961366 (rank : 12)	NC score	0.185531 (rank : 8)
Query Neighborhood Hits	102	Target Neighborhood Hits	40	Shared Neighborhood Hits	18
SwissProt Accessions	P10242, P78391, P78392, P78525, P78526, Q14023, Q14024, Q9UE83	Gene names	MYB
Domain Architecture
Description	Myb proto-oncogene protein (C-myb).

MYB_MOUSE
θ value	0.0961366 (rank : 13)	NC score	0.186789 (rank : 7)
Query Neighborhood Hits	102	Target Neighborhood Hits	39	Shared Neighborhood Hits	18
SwissProt Accessions	P06876, Q61929	Gene names	Myb
Domain Architecture
Description	Myb proto-oncogene protein (C-myb).

SNPC4_MOUSE
θ value	0.0961366 (rank : 14)	NC score	0.164164 (rank : 10)
Query Neighborhood Hits	102	Target Neighborhood Hits	237	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

FLIP1_HUMAN
θ value	0.125558 (rank : 15)	NC score	0.037885 (rank : 50)
Query Neighborhood Hits	102	Target Neighborhood Hits	1405	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

BAT2_HUMAN
θ value	0.163984 (rank : 16)	NC score	0.093517 (rank : 16)
Query Neighborhood Hits	102	Target Neighborhood Hits	931	Shared Neighborhood Hits	36
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

NCOR1_HUMAN
θ value	0.21417 (rank : 17)	NC score	0.078368 (rank : 21)
Query Neighborhood Hits	102	Target Neighborhood Hits	577	Shared Neighborhood Hits	33
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NCOR1_MOUSE
θ value	0.21417 (rank : 18)	NC score	0.082631 (rank : 19)
Query Neighborhood Hits	102	Target Neighborhood Hits	521	Shared Neighborhood Hits	37
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

ZN638_HUMAN
θ value	0.279714 (rank : 19)	NC score	0.053760 (rank : 32)
Query Neighborhood Hits	102	Target Neighborhood Hits	343	Shared Neighborhood Hits	18
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

ATX2_MOUSE
θ value	0.365318 (rank : 20)	NC score	0.053108 (rank : 34)
Query Neighborhood Hits	102	Target Neighborhood Hits	445	Shared Neighborhood Hits	21
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

MINT_MOUSE
θ value	0.365318 (rank : 21)	NC score	0.062489 (rank : 27)
Query Neighborhood Hits	102	Target Neighborhood Hits	1514	Shared Neighborhood Hits	43
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NFH_MOUSE
θ value	0.365318 (rank : 22)	NC score	0.044104 (rank : 46)
Query Neighborhood Hits	102	Target Neighborhood Hits	2247	Shared Neighborhood Hits	58
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

BSN_MOUSE
θ value	0.47712 (rank : 23)	NC score	0.050038 (rank : 36)
Query Neighborhood Hits	102	Target Neighborhood Hits	2057	Shared Neighborhood Hits	60
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

SHAN2_HUMAN
θ value	0.47712 (rank : 24)	NC score	0.056316 (rank : 30)
Query Neighborhood Hits	102	Target Neighborhood Hits	346	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

DDX21_HUMAN
θ value	0.62314 (rank : 25)	NC score	0.020281 (rank : 77)
Query Neighborhood Hits	102	Target Neighborhood Hits	308	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

SNIP_HUMAN
θ value	0.62314 (rank : 26)	NC score	0.064852 (rank : 25)
Query Neighborhood Hits	102	Target Neighborhood Hits	313	Shared Neighborhood Hits	16
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

BAZ2B_HUMAN
θ value	0.813845 (rank : 27)	NC score	0.028379 (rank : 63)
Query Neighborhood Hits	102	Target Neighborhood Hits	803	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

BCOR_HUMAN
θ value	0.813845 (rank : 28)	NC score	0.027319 (rank : 66)
Query Neighborhood Hits	102	Target Neighborhood Hits	609	Shared Neighborhood Hits	18
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

CF146_MOUSE
θ value	0.813845 (rank : 29)	NC score	0.050344 (rank : 35)
Query Neighborhood Hits	102	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D9W6	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf146 homolog.

NOLC1_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.080121 (rank : 20)
Query Neighborhood Hits	102	Target Neighborhood Hits	452	Shared Neighborhood Hits	32
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

SRRM2_MOUSE
θ value	0.813845 (rank : 31)	NC score	0.064162 (rank : 26)
Query Neighborhood Hits	102	Target Neighborhood Hits	1470	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

BBX_MOUSE
θ value	1.06291 (rank : 32)	NC score	0.045680 (rank : 44)
Query Neighborhood Hits	102	Target Neighborhood Hits	152	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

EP300_HUMAN
θ value	1.06291 (rank : 33)	NC score	0.048541 (rank : 38)
Query Neighborhood Hits	102	Target Neighborhood Hits	821	Shared Neighborhood Hits	34
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

FA8_HUMAN
θ value	1.06291 (rank : 34)	NC score	0.028356 (rank : 64)
Query Neighborhood Hits	102	Target Neighborhood Hits	112	Shared Neighborhood Hits	6
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

FLIP1_MOUSE
θ value	1.06291 (rank : 35)	NC score	0.034571 (rank : 52)
Query Neighborhood Hits	102	Target Neighborhood Hits	1176	Shared Neighborhood Hits	29
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

MYBA_HUMAN
θ value	1.06291 (rank : 36)	NC score	0.155166 (rank : 11)
Query Neighborhood Hits	102	Target Neighborhood Hits	48	Shared Neighborhood Hits	19
SwissProt Accessions	P10243	Gene names	MYBL1, AMYB
Domain Architecture
Description	Myb-related protein A (A-Myb).

MYBA_MOUSE
θ value	1.06291 (rank : 37)	NC score	0.154622 (rank : 12)
Query Neighborhood Hits	102	Target Neighborhood Hits	58	Shared Neighborhood Hits	18
SwissProt Accessions	P51960	Gene names	Mybl1, Amyb
Domain Architecture
Description	Myb-related protein A (A-Myb).

RAI14_MOUSE
θ value	1.06291 (rank : 38)	NC score	0.015168 (rank : 89)
Query Neighborhood Hits	102	Target Neighborhood Hits	1505	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

RREB1_HUMAN
θ value	1.06291 (rank : 39)	NC score	0.009035 (rank : 95)
Query Neighborhood Hits	102	Target Neighborhood Hits	879	Shared Neighborhood Hits	10
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

TOP2B_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.060612 (rank : 28)
Query Neighborhood Hits	102	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

EVL_MOUSE
θ value	1.38821 (rank : 41)	NC score	0.047020 (rank : 42)
Query Neighborhood Hits	102	Target Neighborhood Hits	203	Shared Neighborhood Hits	15
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

SI1L3_HUMAN
θ value	1.38821 (rank : 42)	NC score	0.025349 (rank : 69)
Query Neighborhood Hits	102	Target Neighborhood Hits	305	Shared Neighborhood Hits	16
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

BUB1B_HUMAN
θ value	1.81305 (rank : 43)	NC score	0.028663 (rank : 60)
Query Neighborhood Hits	102	Target Neighborhood Hits	208	Shared Neighborhood Hits	6
SwissProt Accessions	O60566, O60501, O60627, O60758, O75389, Q96KM4	Gene names	BUB1B, BUBR1, MAD3L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (hBUBR1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L) (SSK1).

CXXC6_HUMAN
θ value	1.81305 (rank : 44)	NC score	0.048045 (rank : 40)
Query Neighborhood Hits	102	Target Neighborhood Hits	180	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

FOXGA_HUMAN
θ value	1.81305 (rank : 45)	NC score	0.017300 (rank : 87)
Query Neighborhood Hits	102	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

BRE1B_MOUSE
θ value	2.36792 (rank : 46)	NC score	0.018492 (rank : 84)
Query Neighborhood Hits	102	Target Neighborhood Hits	970	Shared Neighborhood Hits	14
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

EVL_HUMAN
θ value	2.36792 (rank : 47)	NC score	0.046113 (rank : 43)
Query Neighborhood Hits	102	Target Neighborhood Hits	260	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

FOXN1_HUMAN
θ value	2.36792 (rank : 48)	NC score	0.017788 (rank : 86)
Query Neighborhood Hits	102	Target Neighborhood Hits	377	Shared Neighborhood Hits	14
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

PRG4_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.045597 (rank : 45)
Query Neighborhood Hits	102	Target Neighborhood Hits	764	Shared Neighborhood Hits	33
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

VRK3_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.022725 (rank : 73)
Query Neighborhood Hits	102	Target Neighborhood Hits	349	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IV63, Q9P2V8	Gene names	VRK3
Domain Architecture
Description	Serine/threonine-protein kinase VRK3 (EC 2.7.11.1) (Vaccinia-related kinase 3).

ZAN_HUMAN
θ value	2.36792 (rank : 51)	NC score	0.028649 (rank : 61)
Query Neighborhood Hits	102	Target Neighborhood Hits	679	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

FA8_MOUSE
θ value	3.0926 (rank : 52)	NC score	0.039225 (rank : 48)
Query Neighborhood Hits	102	Target Neighborhood Hits	100	Shared Neighborhood Hits	6
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

G137B_HUMAN
θ value	3.0926 (rank : 53)	NC score	0.039269 (rank : 47)
Query Neighborhood Hits	102	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	O60478	Gene names	GPR137B, TM7SF1
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR137B (Transmembrane 7 superfamily member 1).

HRX_HUMAN
θ value	3.0926 (rank : 54)	NC score	0.033023 (rank : 54)
Query Neighborhood Hits	102	Target Neighborhood Hits	825	Shared Neighborhood Hits	38
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

INCE_HUMAN
θ value	3.0926 (rank : 55)	NC score	0.025391 (rank : 68)
Query Neighborhood Hits	102	Target Neighborhood Hits	978	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

K1210_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.048298 (rank : 39)
Query Neighborhood Hits	102	Target Neighborhood Hits	219	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

NADAP_HUMAN
θ value	3.0926 (rank : 57)	NC score	0.035272 (rank : 51)
Query Neighborhood Hits	102	Target Neighborhood Hits	208	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

NDE1_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.020200 (rank : 78)
Query Neighborhood Hits	102	Target Neighborhood Hits	823	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

SHAN2_MOUSE
θ value	3.0926 (rank : 59)	NC score	0.037900 (rank : 49)
Query Neighborhood Hits	102	Target Neighborhood Hits	446	Shared Neighborhood Hits	10
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

TCOF_MOUSE
θ value	3.0926 (rank : 60)	NC score	0.047991 (rank : 41)
Query Neighborhood Hits	102	Target Neighborhood Hits	471	Shared Neighborhood Hits	23
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

UBP31_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.022144 (rank : 74)
Query Neighborhood Hits	102	Target Neighborhood Hits	293	Shared Neighborhood Hits	15
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

CIKS_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.032116 (rank : 55)
Query Neighborhood Hits	102	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	O43734, Q5R3A3, Q9H5W2, Q9H6Y3, Q9NS14, Q9UG72	Gene names	TRAF3IP2, C6orf4, C6orf5
Domain Architecture	No domain graphic available
Description	Adapter protein CIKS (Connection to IKK and SAPK/JNK) (TRAF3- interacting protein 2) (Nuclear factor NF-kappa-B activator 1) (ACT1).

MINT_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.049618 (rank : 37)
Query Neighborhood Hits	102	Target Neighborhood Hits	1291	Shared Neighborhood Hits	39
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MYSM1_HUMAN
θ value	4.03905 (rank : 64)	NC score	0.059655 (rank : 29)
Query Neighborhood Hits	102	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VVJ2, Q7Z3G8, Q96PX3	Gene names	MYSM1, KIAA1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

NCOR2_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.071598 (rank : 22)
Query Neighborhood Hits	102	Target Neighborhood Hits	870	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

5HT1B_HUMAN
θ value	5.27518 (rank : 66)	NC score	0.003723 (rank : 101)
Query Neighborhood Hits	102	Target Neighborhood Hits	865	Shared Neighborhood Hits	4
SwissProt Accessions	P28222, Q4VAY7	Gene names	HTR1B, HTR1DB
Domain Architecture
Description	5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5- HT1B) (5-HT-1D-beta) (Serotonin 1D beta receptor) (S12).

CJ119_HUMAN
θ value	5.27518 (rank : 67)	NC score	0.031152 (rank : 56)
Query Neighborhood Hits	102	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BTE3, Q6IA56, Q9BVT9, Q9H916	Gene names	C10orf119
Domain Architecture	No domain graphic available
Description	Protein C10orf119.

CJ119_MOUSE
θ value	5.27518 (rank : 68)	NC score	0.031062 (rank : 57)
Query Neighborhood Hits	102	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3C0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf119 homolog.

DPOD3_HUMAN
θ value	5.27518 (rank : 69)	NC score	0.028254 (rank : 65)
Query Neighborhood Hits	102	Target Neighborhood Hits	109	Shared Neighborhood Hits	12
SwissProt Accessions	Q15054	Gene names	POLD3, KIAA0039
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

PHF20_HUMAN
θ value	5.27518 (rank : 70)	NC score	0.026568 (rank : 67)
Query Neighborhood Hits	102	Target Neighborhood Hits	394	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

QSCN6_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.017847 (rank : 85)
Query Neighborhood Hits	102	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	O00391, Q59G29, Q5T2X0, Q8TDL6, Q8WVP4	Gene names	QSCN6, QSOX1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (hQSOX).

SFPQ_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.023010 (rank : 71)
Query Neighborhood Hits	102	Target Neighborhood Hits	986	Shared Neighborhood Hits	24
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SRRM2_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.071530 (rank : 23)
Query Neighborhood Hits	102	Target Neighborhood Hits	1296	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

WDR79_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.013908 (rank : 90)
Query Neighborhood Hits	102	Target Neighborhood Hits	216	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VC51	Gene names	Wdr79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

5HT1B_MOUSE
θ value	6.88961 (rank : 75)	NC score	0.001983 (rank : 104)
Query Neighborhood Hits	102	Target Neighborhood Hits	861	Shared Neighborhood Hits	3
SwissProt Accessions	P28334	Gene names	Htr1b, 5ht1b
Domain Architecture
Description	5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5- HT1B).

AFF2_HUMAN
θ value	6.88961 (rank : 76)	NC score	0.029345 (rank : 58)
Query Neighborhood Hits	102	Target Neighborhood Hits	218	Shared Neighborhood Hits	21
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

CDC5L_HUMAN
θ value	6.88961 (rank : 77)	NC score	0.095154 (rank : 15)
Query Neighborhood Hits	102	Target Neighborhood Hits	197	Shared Neighborhood Hits	25
SwissProt Accessions	Q99459, Q76N46, Q99974	Gene names	CDC5L, KIAA0432, PCDC5RP
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5- related protein).

CDC5L_MOUSE
θ value	6.88961 (rank : 78)	NC score	0.095897 (rank : 14)
Query Neighborhood Hits	102	Target Neighborhood Hits	205	Shared Neighborhood Hits	24
SwissProt Accessions	Q6A068, Q8K1J9	Gene names	Cdc5l, Kiaa0432
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-related protein (Cdc5-like protein).

FILA_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.024945 (rank : 70)
Query Neighborhood Hits	102	Target Neighborhood Hits	685	Shared Neighborhood Hits	23
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

PI3R6_MOUSE
θ value	6.88961 (rank : 80)	NC score	0.022045 (rank : 75)
Query Neighborhood Hits	102	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U6Q4, Q3TBT5, Q3UAY4, Q8K323	Gene names	Pik3r6
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 6 (Phosphoinositide 3- kinase gamma adapter protein of 87 kDa) (p87 PI3K adapter protein) (p87PIKAP).

SLY_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.018977 (rank : 83)
Query Neighborhood Hits	102	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

SLY_MOUSE
θ value	6.88961 (rank : 82)	NC score	0.018984 (rank : 82)
Query Neighborhood Hits	102	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

TAF3_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.028929 (rank : 59)
Query Neighborhood Hits	102	Target Neighborhood Hits	568	Shared Neighborhood Hits	23
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TITIN_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.008033 (rank : 97)
Query Neighborhood Hits	102	Target Neighborhood Hits	2923	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TTBK1_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.008518 (rank : 96)
Query Neighborhood Hits	102	Target Neighborhood Hits	1058	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

AAK1_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.006720 (rank : 99)
Query Neighborhood Hits	102	Target Neighborhood Hits	1051	Shared Neighborhood Hits	23
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

CAF1B_HUMAN
θ value	8.99809 (rank : 87)	NC score	0.011104 (rank : 93)
Query Neighborhood Hits	102	Target Neighborhood Hits	345	Shared Neighborhood Hits	11
SwissProt Accessions	Q13112, Q99548	Gene names	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60) (M- phase phosphoprotein 7).

CI078_HUMAN
θ value	8.99809 (rank : 88)	NC score	0.019070 (rank : 81)
Query Neighborhood Hits	102	Target Neighborhood Hits	66	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NZ63, Q8WVU6, Q9NT39	Gene names	C9orf78
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf78 (Hepatocellular carcinoma-associated antigen 59).

CTGE5_MOUSE
θ value	8.99809 (rank : 89)	NC score	0.012200 (rank : 92)
Query Neighborhood Hits	102	Target Neighborhood Hits	928	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

DLX4_HUMAN
θ value	8.99809 (rank : 90)	NC score	0.002944 (rank : 103)
Query Neighborhood Hits	102	Target Neighborhood Hits	350	Shared Neighborhood Hits	3
SwissProt Accessions	Q92988, O60480, Q13265, Q6PJK0, Q9HBE0	Gene names	DLX4, BP1, DLX7, DLX8
Domain Architecture	No domain graphic available
Description	Homeobox protein DLX-4 (DLX-7) (DLX-8) (Beta protein 1).

FGD1_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.005969 (rank : 100)
Query Neighborhood Hits	102	Target Neighborhood Hits	367	Shared Neighborhood Hits	8
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

GCC2_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.019504 (rank : 80)
Query Neighborhood Hits	102	Target Neighborhood Hits	1619	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

GPTC8_HUMAN
θ value	8.99809 (rank : 93)	NC score	0.033834 (rank : 53)
Query Neighborhood Hits	102	Target Neighborhood Hits	366	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

ITPR2_HUMAN
θ value	8.99809 (rank : 94)	NC score	0.006827 (rank : 98)
Query Neighborhood Hits	102	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q14571, O94773	Gene names	ITPR2
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2).

K0690_MOUSE
θ value	8.99809 (rank : 95)	NC score	0.019717 (rank : 79)
Query Neighborhood Hits	102	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P5B0, Q7TMI5, Q80TU2	Gene names	Kiaa0690
Domain Architecture	No domain graphic available
Description	Protein KIAA0690.

KI21B_MOUSE
θ value	8.99809 (rank : 96)	NC score	0.009459 (rank : 94)
Query Neighborhood Hits	102	Target Neighborhood Hits	997	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

MAP1B_MOUSE
θ value	8.99809 (rank : 97)	NC score	0.028483 (rank : 62)
Query Neighborhood Hits	102	Target Neighborhood Hits	977	Shared Neighborhood Hits	34
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MYO9B_HUMAN
θ value	8.99809 (rank : 98)	NC score	0.017236 (rank : 88)
Query Neighborhood Hits	102	Target Neighborhood Hits	641	Shared Neighborhood Hits	31
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

PHF2_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.013650 (rank : 91)
Query Neighborhood Hits	102	Target Neighborhood Hits	208	Shared Neighborhood Hits	15
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

PRB4S_HUMAN
θ value	8.99809 (rank : 100)	NC score	0.021320 (rank : 76)
Query Neighborhood Hits	102	Target Neighborhood Hits	330	Shared Neighborhood Hits	15
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

ROCK2_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.002966 (rank : 102)
Query Neighborhood Hits	102	Target Neighborhood Hits	2073	Shared Neighborhood Hits	25
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

TB182_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.022873 (rank : 72)
Query Neighborhood Hits	102	Target Neighborhood Hits	414	Shared Neighborhood Hits	14
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

MDC1_MOUSE
θ value	θ > 10 (rank : 103)	NC score	0.053316 (rank : 33)
Query Neighborhood Hits	102	Target Neighborhood Hits	998	Shared Neighborhood Hits	40
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

NCOR2_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.054790 (rank : 31)
Query Neighborhood Hits	102	Target Neighborhood Hits	790	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

Hits sorted by NC score

TERF2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	102	Target Neighborhood Hits	102	Shared Neighborhood Hits	102
SwissProt Accessions	Q15554	Gene names	TERF2, TRF2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

TERF2_MOUSE
NC score	0.950140 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	102	Target Neighborhood Hits	128	Shared Neighborhood Hits	37
SwissProt Accessions	O35144	Gene names	Terf2, Trf2
Domain Architecture
Description	Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein).

TERF1_HUMAN
NC score	0.729966 (rank : 3)	θ value	6.38894e-30 (rank : 3)
Query Neighborhood Hits	102	Target Neighborhood Hits	83	Shared Neighborhood Hits	22
SwissProt Accessions	P54274, Q15553, Q93029	Gene names	TERF1, PIN2, TRF, TRF1
Domain Architecture
Description	Telomeric repeat-binding factor 1 (TTAGGG repeat-binding factor 1) (NIMA-interacting protein 2) (Telomeric protein Pin2/TRF1).

TERF1_MOUSE
NC score	0.717232 (rank : 4)	θ value	5.79196e-23 (rank : 4)
Query Neighborhood Hits	102	Target Neighborhood Hits	31	Shared Neighborhood Hits	14
SwissProt Accessions	P70371, Q9CY71	Gene names	Terf1, Trf1
Domain Architecture
Description	Telomeric repeat-binding factor 1 (TTAGGG repeat-binding factor 1).

MYBB_HUMAN
NC score	0.208608 (rank : 5)	θ value	0.00869519 (rank : 6)
Query Neighborhood Hits	102	Target Neighborhood Hits	78	Shared Neighborhood Hits	22
SwissProt Accessions	P10244	Gene names	MYBL2, BMYB
Domain Architecture
Description	Myb-related protein B (B-Myb).

MYBB_MOUSE
NC score	0.201467 (rank : 6)	θ value	0.0252991 (rank : 9)
Query Neighborhood Hits	102	Target Neighborhood Hits	73	Shared Neighborhood Hits	22
SwissProt Accessions	P48972	Gene names	Mybl2, Bmyb
Domain Architecture
Description	Myb-related protein B (B-Myb).

MYB_MOUSE
NC score	0.186789 (rank : 7)	θ value	0.0961366 (rank : 13)
Query Neighborhood Hits	102	Target Neighborhood Hits	39	Shared Neighborhood Hits	18
SwissProt Accessions	P06876, Q61929	Gene names	Myb
Domain Architecture
Description	Myb proto-oncogene protein (C-myb).

MYB_HUMAN
NC score	0.185531 (rank : 8)	θ value	0.0961366 (rank : 12)
Query Neighborhood Hits	102	Target Neighborhood Hits	40	Shared Neighborhood Hits	18
SwissProt Accessions	P10242, P78391, P78392, P78525, P78526, Q14023, Q14024, Q9UE83	Gene names	MYB
Domain Architecture
Description	Myb proto-oncogene protein (C-myb).

SNPC4_HUMAN
NC score	0.167112 (rank : 9)	θ value	0.0431538 (rank : 10)
Query Neighborhood Hits	102	Target Neighborhood Hits	589	Shared Neighborhood Hits	36
SwissProt Accessions	Q5SXM2, Q9Y6P7	Gene names	SNAPC4, SNAP190
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit) (Proximal sequence element-binding transcription factor subunit alpha) (PSE-binding factor subunit alpha) (PTF subunit alpha).

SNPC4_MOUSE
NC score	0.164164 (rank : 10)	θ value	0.0961366 (rank : 14)
Query Neighborhood Hits	102	Target Neighborhood Hits	237	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BP86, Q6PGG7, Q80UG9, Q810L1	Gene names	Snapc4
Domain Architecture	No domain graphic available
Description	snRNA-activating protein complex subunit 4 (SNAPc subunit 4) (snRNA- activating protein complex 190 kDa subunit) (SNAPc 190 kDa subunit).

MYBA_HUMAN
NC score	0.155166 (rank : 11)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	102	Target Neighborhood Hits	48	Shared Neighborhood Hits	19
SwissProt Accessions	P10243	Gene names	MYBL1, AMYB
Domain Architecture
Description	Myb-related protein A (A-Myb).

MYBA_MOUSE
NC score	0.154622 (rank : 12)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	102	Target Neighborhood Hits	58	Shared Neighborhood Hits	18
SwissProt Accessions	P51960	Gene names	Mybl1, Amyb
Domain Architecture
Description	Myb-related protein A (A-Myb).

BAT2_MOUSE
NC score	0.098599 (rank : 13)	θ value	0.0961366 (rank : 11)
Query Neighborhood Hits	102	Target Neighborhood Hits	947	Shared Neighborhood Hits	37
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CDC5L_MOUSE
NC score	0.095897 (rank : 14)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	102	Target Neighborhood Hits	205	Shared Neighborhood Hits	24
SwissProt Accessions	Q6A068, Q8K1J9	Gene names	Cdc5l, Kiaa0432
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-related protein (Cdc5-like protein).

CDC5L_HUMAN
NC score	0.095154 (rank : 15)	θ value	6.88961 (rank : 77)
Query Neighborhood Hits	102	Target Neighborhood Hits	197	Shared Neighborhood Hits	25
SwissProt Accessions	Q99459, Q76N46, Q99974	Gene names	CDC5L, KIAA0432, PCDC5RP
Domain Architecture	No domain graphic available
Description	Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5- related protein).

BAT2_HUMAN
NC score	0.093517 (rank : 16)	θ value	0.163984 (rank : 16)
Query Neighborhood Hits	102	Target Neighborhood Hits	931	Shared Neighborhood Hits	36
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

TOP2B_MOUSE
NC score	0.087293 (rank : 17)	θ value	0.00869519 (rank : 7)
Query Neighborhood Hits	102	Target Neighborhood Hits	80	Shared Neighborhood Hits	5
SwissProt Accessions	Q64511, Q7TQG4	Gene names	Top2b
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

MDC1_HUMAN
NC score	0.083255 (rank : 18)	θ value	0.00134147 (rank : 5)
Query Neighborhood Hits	102	Target Neighborhood Hits	1446	Shared Neighborhood Hits	52
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

NCOR1_MOUSE
NC score	0.082631 (rank : 19)	θ value	0.21417 (rank : 18)
Query Neighborhood Hits	102	Target Neighborhood Hits	521	Shared Neighborhood Hits	37
SwissProt Accessions	Q60974, Q60812	Gene names	Ncor1, Rxrip13
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR) (Retinoid X receptor- interacting protein 13) (RIP13).

NOLC1_HUMAN
NC score	0.080121 (rank : 20)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	102	Target Neighborhood Hits	452	Shared Neighborhood Hits	32
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

NCOR1_HUMAN
NC score	0.078368 (rank : 21)	θ value	0.21417 (rank : 17)
Query Neighborhood Hits	102	Target Neighborhood Hits	577	Shared Neighborhood Hits	33
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NCOR2_HUMAN
NC score	0.071598 (rank : 22)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	102	Target Neighborhood Hits	870	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

SRRM2_HUMAN
NC score	0.071530 (rank : 23)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	102	Target Neighborhood Hits	1296	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

DNM3A_HUMAN
NC score	0.067802 (rank : 24)	θ value	0.0252991 (rank : 8)
Query Neighborhood Hits	102	Target Neighborhood Hits	104	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y6K1, Q8WXU9	Gene names	DNMT3A
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 3A (EC 2.1.1.37) (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA).

SNIP_HUMAN
NC score	0.064852 (rank : 25)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	102	Target Neighborhood Hits	313	Shared Neighborhood Hits	16
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

SRRM2_MOUSE
NC score	0.064162 (rank : 26)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	102	Target Neighborhood Hits	1470	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

MINT_MOUSE
NC score	0.062489 (rank : 27)	θ value	0.365318 (rank : 21)
Query Neighborhood Hits	102	Target Neighborhood Hits	1514	Shared Neighborhood Hits	43
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

TOP2B_HUMAN
NC score	0.060612 (rank : 28)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	102	Target Neighborhood Hits	101	Shared Neighborhood Hits	8
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

MYSM1_HUMAN
NC score	0.059655 (rank : 29)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	102	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VVJ2, Q7Z3G8, Q96PX3	Gene names	MYSM1, KIAA1915
Domain Architecture	No domain graphic available
Description	Protein MYSM1 (Myb-like, SWIRM and MPN domain-containing protein 1).

SHAN2_HUMAN
NC score	0.056316 (rank : 30)	θ value	0.47712 (rank : 24)
Query Neighborhood Hits	102	Target Neighborhood Hits	346	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UPX8, Q3Y8G9, Q52LK2, Q9UKP1	Gene names	SHANK2, KIAA1022
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2).

NCOR2_MOUSE
NC score	0.054790 (rank : 31)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	102	Target Neighborhood Hits	790	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WU42, Q9WU43, Q9WUC1	Gene names	Ncor2, Smrt
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC).

ZN638_HUMAN
NC score	0.053760 (rank : 32)	θ value	0.279714 (rank : 19)
Query Neighborhood Hits	102	Target Neighborhood Hits	343	Shared Neighborhood Hits	18
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

MDC1_MOUSE
NC score	0.053316 (rank : 33)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	102	Target Neighborhood Hits	998	Shared Neighborhood Hits	40
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

ATX2_MOUSE
NC score	0.053108 (rank : 34)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	102	Target Neighborhood Hits	445	Shared Neighborhood Hits	21
SwissProt Accessions	O70305, P97421	Gene names	Atxn2, Atx2, Sca2
Domain Architecture	No domain graphic available
Description	Ataxin-2 (Spinocerebellar ataxia type 2 protein homolog).

CF146_MOUSE
NC score	0.050344 (rank : 35)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	102	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D9W6	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf146 homolog.

BSN_MOUSE
NC score	0.050038 (rank : 36)	θ value	0.47712 (rank : 23)
Query Neighborhood Hits	102	Target Neighborhood Hits	2057	Shared Neighborhood Hits	60
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

MINT_HUMAN
NC score	0.049618 (rank : 37)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	102	Target Neighborhood Hits	1291	Shared Neighborhood Hits	39
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

EP300_HUMAN
NC score	0.048541 (rank : 38)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	102	Target Neighborhood Hits	821	Shared Neighborhood Hits	34
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

K1210_HUMAN
NC score	0.048298 (rank : 39)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	102	Target Neighborhood Hits	219	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ULL0, Q5JPN4	Gene names	KIAA1210
Domain Architecture	No domain graphic available
Description	Protein KIAA1210.

CXXC6_HUMAN
NC score	0.048045 (rank : 40)	θ value	1.81305 (rank : 44)
Query Neighborhood Hits	102	Target Neighborhood Hits	180	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NFU7, Q5VUP7, Q7Z6B6, Q8TCR1, Q9C0I7	Gene names	CXXC6, KIAA1676, LCX
Domain Architecture	No domain graphic available
Description	CXXC-type zinc finger protein 6 (Leukemia-associated protein with a CXXC domain).

TCOF_MOUSE
NC score	0.047991 (rank : 41)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	102	Target Neighborhood Hits	471	Shared Neighborhood Hits	23
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

EVL_MOUSE
NC score	0.047020 (rank : 42)	θ value	1.38821 (rank : 41)
Query Neighborhood Hits	102	Target Neighborhood Hits	203	Shared Neighborhood Hits	15
SwissProt Accessions	P70429, Q9ERU8	Gene names	Evl
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

EVL_HUMAN
NC score	0.046113 (rank : 43)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	102	Target Neighborhood Hits	260	Shared Neighborhood Hits	14
SwissProt Accessions	Q9UI08, O95884, Q7Z522, Q8TBV1, Q9UF25, Q9UIC2	Gene names	EVL, RNB6
Domain Architecture
Description	Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein- like).

BBX_MOUSE
NC score	0.045680 (rank : 44)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	102	Target Neighborhood Hits	152	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VBW5, Q3TZK1, Q6NXY8, Q6PEU3, Q8BQJ7, Q8C7E0, Q8CDQ0, Q8CDV1, Q8VI48, Q8VI49, Q8VI50, Q9CS94	Gene names	Bbx, Hbp2
Domain Architecture	No domain graphic available
Description	HMG box transcription factor BBX (Bobby sox homolog) (HMG box- containing protein 2).

PRG4_HUMAN
NC score	0.045597 (rank : 45)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	102	Target Neighborhood Hits	764	Shared Neighborhood Hits	33
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

NFH_MOUSE
NC score	0.044104 (rank : 46)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	102	Target Neighborhood Hits	2247	Shared Neighborhood Hits	58
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

G137B_HUMAN
NC score	0.039269 (rank : 47)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	102	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	O60478	Gene names	GPR137B, TM7SF1
Domain Architecture	No domain graphic available
Description	Integral membrane protein GPR137B (Transmembrane 7 superfamily member 1).

FA8_MOUSE
NC score	0.039225 (rank : 48)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	102	Target Neighborhood Hits	100	Shared Neighborhood Hits	6
SwissProt Accessions	Q06194	Gene names	F8, Cf8, F8c
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component).

SHAN2_MOUSE
NC score	0.037900 (rank : 49)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	102	Target Neighborhood Hits	446	Shared Neighborhood Hits	10
SwissProt Accessions	Q80Z38, Q3UTK4, Q5DU07	Gene names	Shank2, Kiaa1022
Domain Architecture	No domain graphic available
Description	SH3 and multiple ankyrin repeat domains protein 2 (Shank2) (Cortactin- binding protein 1) (CortBP1).

FLIP1_HUMAN
NC score	0.037885 (rank : 50)	θ value	0.125558 (rank : 15)
Query Neighborhood Hits	102	Target Neighborhood Hits	1405	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

NADAP_HUMAN
NC score	0.035272 (rank : 51)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	102	Target Neighborhood Hits	208	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BWU0, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2	Gene names	SLC4A1AP, HLC3
Domain Architecture	No domain graphic available
Description	Kanadaptin (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein) (Lung cancer oncogene 3 protein).

FLIP1_MOUSE
NC score	0.034571 (rank : 52)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	102	Target Neighborhood Hits	1176	Shared Neighborhood Hits	29
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GPTC8_HUMAN
NC score	0.033834 (rank : 53)	θ value	8.99809 (rank : 93)
Query Neighborhood Hits	102	Target Neighborhood Hits	366	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

HRX_HUMAN
NC score	0.033023 (rank : 54)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	102	Target Neighborhood Hits	825	Shared Neighborhood Hits	38
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

CIKS_HUMAN
NC score	0.032116 (rank : 55)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	102	Target Neighborhood Hits	60	Shared Neighborhood Hits	2
SwissProt Accessions	O43734, Q5R3A3, Q9H5W2, Q9H6Y3, Q9NS14, Q9UG72	Gene names	TRAF3IP2, C6orf4, C6orf5
Domain Architecture	No domain graphic available
Description	Adapter protein CIKS (Connection to IKK and SAPK/JNK) (TRAF3- interacting protein 2) (Nuclear factor NF-kappa-B activator 1) (ACT1).

CJ119_HUMAN
NC score	0.031152 (rank : 56)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	102	Target Neighborhood Hits	14	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BTE3, Q6IA56, Q9BVT9, Q9H916	Gene names	C10orf119
Domain Architecture	No domain graphic available
Description	Protein C10orf119.

CJ119_MOUSE
NC score	0.031062 (rank : 57)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	102	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3C0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf119 homolog.

AFF2_HUMAN
NC score	0.029345 (rank : 58)	θ value	6.88961 (rank : 76)
Query Neighborhood Hits	102	Target Neighborhood Hits	218	Shared Neighborhood Hits	21
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

TAF3_HUMAN
NC score	0.028929 (rank : 59)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	102	Target Neighborhood Hits	568	Shared Neighborhood Hits	23
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

BUB1B_HUMAN
NC score	0.028663 (rank : 60)	θ value	1.81305 (rank : 43)
Query Neighborhood Hits	102	Target Neighborhood Hits	208	Shared Neighborhood Hits	6
SwissProt Accessions	O60566, O60501, O60627, O60758, O75389, Q96KM4	Gene names	BUB1B, BUBR1, MAD3L
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (hBUBR1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L) (SSK1).

ZAN_HUMAN
NC score	0.028649 (rank : 61)	θ value	2.36792 (rank : 51)
Query Neighborhood Hits	102	Target Neighborhood Hits	679	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

MAP1B_MOUSE
NC score	0.028483 (rank : 62)	θ value	8.99809 (rank : 97)
Query Neighborhood Hits	102	Target Neighborhood Hits	977	Shared Neighborhood Hits	34
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

BAZ2B_HUMAN
NC score	0.028379 (rank : 63)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	102	Target Neighborhood Hits	803	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

FA8_HUMAN
NC score	0.028356 (rank : 64)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	102	Target Neighborhood Hits	112	Shared Neighborhood Hits	6
SwissProt Accessions	P00451	Gene names	F8, F8C
Domain Architecture
Description	Coagulation factor VIII precursor (Procoagulant component) (Antihemophilic factor) (AHF) [Contains: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain].

DPOD3_HUMAN
NC score	0.028254 (rank : 65)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	102	Target Neighborhood Hits	109	Shared Neighborhood Hits	12
SwissProt Accessions	Q15054	Gene names	POLD3, KIAA0039
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

BCOR_HUMAN
NC score	0.027319 (rank : 66)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	102	Target Neighborhood Hits	609	Shared Neighborhood Hits	18
SwissProt Accessions	Q6W2J9, Q6P4B6, Q7Z2K7, Q8TEB4, Q96DB3, Q9H232, Q9H233, Q9HCJ7, Q9NXF2	Gene names	BCOR, KIAA1575
Domain Architecture	No domain graphic available
Description	BCoR protein (BCL-6 corepressor).

PHF20_HUMAN
NC score	0.026568 (rank : 67)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	102	Target Neighborhood Hits	394	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

INCE_HUMAN
NC score	0.025391 (rank : 68)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	102	Target Neighborhood Hits	978	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

SI1L3_HUMAN
NC score	0.025349 (rank : 69)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	102	Target Neighborhood Hits	305	Shared Neighborhood Hits	16
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

FILA_HUMAN
NC score	0.024945 (rank : 70)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	102	Target Neighborhood Hits	685	Shared Neighborhood Hits	23
SwissProt Accessions	P20930, Q01720, Q5T583	Gene names	FLG
Domain Architecture	No domain graphic available
Description	Filaggrin.

SFPQ_HUMAN
NC score	0.023010 (rank : 71)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	102	Target Neighborhood Hits	986	Shared Neighborhood Hits	24
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

TB182_HUMAN
NC score	0.022873 (rank : 72)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	102	Target Neighborhood Hits	414	Shared Neighborhood Hits	14
SwissProt Accessions	Q9C0C2	Gene names	TNKS1BP1, KIAA1741, TAB182
Domain Architecture	No domain graphic available
Description	182 kDa tankyrase 1-binding protein.

VRK3_HUMAN
NC score	0.022725 (rank : 73)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	102	Target Neighborhood Hits	349	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IV63, Q9P2V8	Gene names	VRK3
Domain Architecture
Description	Serine/threonine-protein kinase VRK3 (EC 2.7.11.1) (Vaccinia-related kinase 3).

UBP31_HUMAN
NC score	0.022144 (rank : 74)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	102	Target Neighborhood Hits	293	Shared Neighborhood Hits	15
SwissProt Accessions	Q70CQ4, Q6AW97, Q6ZTC0, Q6ZTN2, Q9ULL7	Gene names	USP31, KIAA1203
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 31 (EC 3.1.2.15) (Ubiquitin thioesterase 31) (Ubiquitin-specific-processing protease 31) (Deubiquitinating enzyme 31).

PI3R6_MOUSE
NC score	0.022045 (rank : 75)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	102	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q3U6Q4, Q3TBT5, Q3UAY4, Q8K323	Gene names	Pik3r6
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 6 (Phosphoinositide 3- kinase gamma adapter protein of 87 kDa) (p87 PI3K adapter protein) (p87PIKAP).

PRB4S_HUMAN
NC score	0.021320 (rank : 76)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	102	Target Neighborhood Hits	330	Shared Neighborhood Hits	15
SwissProt Accessions	P10163, P02813	Gene names	PRB4
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 4 allele S precursor (Salivary proline-rich protein Po) (Parotid o protein) [Contains: Protein N1; Glycosylated protein A].

DDX21_HUMAN
NC score	0.020281 (rank : 77)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	102	Target Neighborhood Hits	308	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NR30, Q13436, Q5VX41, Q68D35	Gene names	DDX21
Domain Architecture
Description	Nucleolar RNA helicase 2 (EC 3.6.1.-) (Nucleolar RNA helicase II) (Nucleolar RNA helicase Gu) (RH II/Gu) (Gu-alpha) (DEAD box protein 21).

NDE1_HUMAN
NC score	0.020200 (rank : 78)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	102	Target Neighborhood Hits	823	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NXR1, Q49AQ2	Gene names	NDE1, NUDE
Domain Architecture	No domain graphic available
Description	Nuclear distribution protein nudE homolog 1 (NudE).

K0690_MOUSE
NC score	0.019717 (rank : 79)	θ value	8.99809 (rank : 95)
Query Neighborhood Hits	102	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P5B0, Q7TMI5, Q80TU2	Gene names	Kiaa0690
Domain Architecture	No domain graphic available
Description	Protein KIAA0690.

GCC2_MOUSE
NC score	0.019504 (rank : 80)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	102	Target Neighborhood Hits	1619	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

CI078_HUMAN
NC score	0.019070 (rank : 81)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	102	Target Neighborhood Hits	66	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NZ63, Q8WVU6, Q9NT39	Gene names	C9orf78
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf78 (Hepatocellular carcinoma-associated antigen 59).

SLY_MOUSE
NC score	0.018984 (rank : 82)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	102	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K352, Q3TBX0, Q9DBV2	Gene names	Sly
Domain Architecture
Description	SH3 protein expressed in lymphocytes.

SLY_HUMAN
NC score	0.018977 (rank : 83)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	102	Target Neighborhood Hits	81	Shared Neighborhood Hits	4
SwissProt Accessions	O75995	Gene names	SLY, CXorf9
Domain Architecture
Description	SH3 protein expressed in lymphocytes homolog.

BRE1B_MOUSE
NC score	0.018492 (rank : 84)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	102	Target Neighborhood Hits	970	Shared Neighborhood Hits	14
SwissProt Accessions	Q3U319, Q6ZQ75, Q8BJA1, Q8BY03, Q8CHX4	Gene names	Rnf40, Bre1b, Kiaa0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40).

QSCN6_HUMAN
NC score	0.017847 (rank : 85)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	102	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	O00391, Q59G29, Q5T2X0, Q8TDL6, Q8WVP4	Gene names	QSCN6, QSOX1
Domain Architecture	No domain graphic available
Description	Sulfhydryl oxidase 1 precursor (EC 1.8.3.2) (Quiescin Q6) (hQSOX).

FOXN1_HUMAN
NC score	0.017788 (rank : 86)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	102	Target Neighborhood Hits	377	Shared Neighborhood Hits	14
SwissProt Accessions	O15353, O15352	Gene names	FOXN1, WHN
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude).

FOXGA_HUMAN
NC score	0.017300 (rank : 87)	θ value	1.81305 (rank : 45)
Query Neighborhood Hits	102	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	P55316	Gene names	FOXG1A, FKHL2
Domain Architecture
Description	Forkhead box protein G1A (Forkhead-related protein FKHL2) (Transcription factor BF-2) (Brain factor 2) (BF2) (HFK2).

MYO9B_HUMAN
NC score	0.017236 (rank : 88)	θ value	8.99809 (rank : 98)
Query Neighborhood Hits	102	Target Neighborhood Hits	641	Shared Neighborhood Hits	31
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

RAI14_MOUSE
NC score	0.015168 (rank : 89)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	102	Target Neighborhood Hits	1505	Shared Neighborhood Hits	26
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

WDR79_MOUSE
NC score	0.013908 (rank : 90)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	102	Target Neighborhood Hits	216	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VC51	Gene names	Wdr79
Domain Architecture	No domain graphic available
Description	WD repeat protein 79.

PHF2_HUMAN
NC score	0.013650 (rank : 91)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	102	Target Neighborhood Hits	208	Shared Neighborhood Hits	15
SwissProt Accessions	O75151, Q8N3K2, Q9Y6N4	Gene names	PHF2, KIAA0662
Domain Architecture
Description	PHD finger protein 2 (GRC5).

CTGE5_MOUSE
NC score	0.012200 (rank : 92)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	102	Target Neighborhood Hits	928	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

CAF1B_HUMAN
NC score	0.011104 (rank : 93)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	102	Target Neighborhood Hits	345	Shared Neighborhood Hits	11
SwissProt Accessions	Q13112, Q99548	Gene names	CHAF1B, CAF1A, CAF1P60, MPHOSPH7, MPP7
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60) (M- phase phosphoprotein 7).

KI21B_MOUSE
NC score	0.009459 (rank : 94)	θ value	8.99809 (rank : 96)
Query Neighborhood Hits	102	Target Neighborhood Hits	997	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QXL1, P97424	Gene names	Kif21b, Kif6
Domain Architecture	No domain graphic available
Description	Kinesin family member 21B (Kinesin-like protein KIF6).

RREB1_HUMAN
NC score	0.009035 (rank : 95)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	102	Target Neighborhood Hits	879	Shared Neighborhood Hits	10
SwissProt Accessions	Q92766, O75567	Gene names	RREB1
Domain Architecture
Description	RAS-responsive element-binding protein 1 (RREB-1) (Raf-responsive zinc finger protein LZ321).

TTBK1_HUMAN
NC score	0.008518 (rank : 96)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	102	Target Neighborhood Hits	1058	Shared Neighborhood Hits	19
SwissProt Accessions	Q5TCY1, Q2L6C6, Q8N444, Q96JH2	Gene names	TTBK1, BDTK, KIAA1855
Domain Architecture	No domain graphic available
Description	Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase).

TITIN_HUMAN
NC score	0.008033 (rank : 97)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	102	Target Neighborhood Hits	2923	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ITPR2_HUMAN
NC score	0.006827 (rank : 98)	θ value	8.99809 (rank : 94)
Query Neighborhood Hits	102	Target Neighborhood Hits	74	Shared Neighborhood Hits	2
SwissProt Accessions	Q14571, O94773	Gene names	ITPR2
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2).

AAK1_MOUSE
NC score	0.006720 (rank : 99)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	102	Target Neighborhood Hits	1051	Shared Neighborhood Hits	23
SwissProt Accessions	Q3UHJ0, Q3TY53, Q6ZPZ6, Q80XP6	Gene names	Aak1, Kiaa1048
Domain Architecture	No domain graphic available
Description	AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1).

FGD1_HUMAN
NC score	0.005969 (rank : 100)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	102	Target Neighborhood Hits	367	Shared Neighborhood Hits	8
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

5HT1B_HUMAN
NC score	0.003723 (rank : 101)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	102	Target Neighborhood Hits	865	Shared Neighborhood Hits	4
SwissProt Accessions	P28222, Q4VAY7	Gene names	HTR1B, HTR1DB
Domain Architecture
Description	5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5- HT1B) (5-HT-1D-beta) (Serotonin 1D beta receptor) (S12).

ROCK2_HUMAN
NC score	0.002966 (rank : 102)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	102	Target Neighborhood Hits	2073	Shared Neighborhood Hits	25
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

DLX4_HUMAN
NC score	0.002944 (rank : 103)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	102	Target Neighborhood Hits	350	Shared Neighborhood Hits	3
SwissProt Accessions	Q92988, O60480, Q13265, Q6PJK0, Q9HBE0	Gene names	DLX4, BP1, DLX7, DLX8
Domain Architecture	No domain graphic available
Description	Homeobox protein DLX-4 (DLX-7) (DLX-8) (Beta protein 1).

5HT1B_MOUSE
NC score	0.001983 (rank : 104)	θ value	6.88961 (rank : 75)
Query Neighborhood Hits	102	Target Neighborhood Hits	861	Shared Neighborhood Hits	3
SwissProt Accessions	P28334	Gene names	Htr1b, 5ht1b
Domain Architecture
Description	5-hydroxytryptamine 1B receptor (5-HT-1B) (Serotonin receptor 1B) (5- HT1B).