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Network neighborhood for query Sequence : C163B_HUMAN

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C163B_HUMAN
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

C163A_HUMAN
θ value	0 (rank : 1)	NC score	0.991627 (rank : 2)
Query Neighborhood Hits	64	Target Neighborhood Hits	54	Shared Neighborhood Hits	36
SwissProt Accessions	Q86VB7, Q07898, Q07899, Q07900, Q07901, Q2VLH7	Gene names	CD163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) (Hemoglobin scavenger receptor) [Contains: Soluble CD163 (sCD163)].

C163A_MOUSE
θ value	0 (rank : 2)	NC score	0.991469 (rank : 3)
Query Neighborhood Hits	64	Target Neighborhood Hits	48	Shared Neighborhood Hits	36
SwissProt Accessions	Q2VLH6, Q2VLH5, Q99MX8	Gene names	Cd163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) [Contains: Soluble CD163 (sCD163)].

C163B_HUMAN
θ value	0 (rank : 3)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	64	Target Neighborhood Hits	64	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

DMBT1_HUMAN
θ value	0 (rank : 4)	NC score	0.795238 (rank : 15)
Query Neighborhood Hits	64	Target Neighborhood Hits	152	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DMBT1_MOUSE
θ value	1.31915e-176 (rank : 5)	NC score	0.715717 (rank : 16)
Query Neighborhood Hits	64	Target Neighborhood Hits	134	Shared Neighborhood Hits	38
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

NETR_HUMAN
θ value	8.49582e-83 (rank : 6)	NC score	0.468931 (rank : 22)
Query Neighborhood Hits	64	Target Neighborhood Hits	218	Shared Neighborhood Hits	42
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

CD5L_HUMAN
θ value	1.27248e-70 (rank : 7)	NC score	0.950819 (rank : 4)
Query Neighborhood Hits	64	Target Neighborhood Hits	45	Shared Neighborhood Hits	37
SwissProt Accessions	O43866, Q6UX63	Gene names	CD5L
Domain Architecture
Description	CD5 antigen-like precursor (SP-alpha) (CT-2) (IgM-associated peptide).

NETR_MOUSE
θ value	1.07722e-69 (rank : 8)	NC score	0.453495 (rank : 23)
Query Neighborhood Hits	64	Target Neighborhood Hits	216	Shared Neighborhood Hits	42
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

CD5L_MOUSE
θ value	2.24614e-67 (rank : 9)	NC score	0.949563 (rank : 5)
Query Neighborhood Hits	64	Target Neighborhood Hits	49	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QWK4, O35300, O35301, Q505P6, Q91W05	Gene names	Cd5l, Aim, Api6
Domain Architecture
Description	CD5 antigen-like precursor (SP-alpha) (CT-2) (Apoptosis inhibitory 6) (Apoptosis inhibitor expressed by macrophages).

LOXL3_MOUSE
θ value	1.01059e-59 (rank : 10)	NC score	0.822240 (rank : 11)
Query Neighborhood Hits	64	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z175, Q9JJ39	Gene names	Loxl3, Lor2
Domain Architecture
Description	Lysyl oxidase homolog 3 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 3) (Lysyl oxidase-related protein 2).

LOXL4_MOUSE
θ value	5.0155e-59 (rank : 11)	NC score	0.823247 (rank : 9)
Query Neighborhood Hits	64	Target Neighborhood Hits	50	Shared Neighborhood Hits	33
SwissProt Accessions	Q924C6	Gene names	Loxl4, Loxc
Domain Architecture
Description	Lysyl oxidase homolog 4 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 4) (Lysyl oxidase-related protein C).

LOXL3_HUMAN
θ value	6.55044e-59 (rank : 12)	NC score	0.820612 (rank : 12)
Query Neighborhood Hits	64	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	P58215, Q96RS1	Gene names	LOXL3, LOXL
Domain Architecture
Description	Lysyl oxidase homolog 3 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 3).

LOXL4_HUMAN
θ value	2.7521e-57 (rank : 13)	NC score	0.822786 (rank : 10)
Query Neighborhood Hits	64	Target Neighborhood Hits	43	Shared Neighborhood Hits	35
SwissProt Accessions	Q96JB6, Q96DY1, Q96PC0, Q9H6T5	Gene names	LOXL4, LOXC
Domain Architecture
Description	Lysyl oxidase homolog 4 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 4) (Lysyl oxidase-related protein C).

LOXL2_HUMAN
θ value	1.08223e-53 (rank : 14)	NC score	0.818968 (rank : 14)
Query Neighborhood Hits	64	Target Neighborhood Hits	49	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y4K0, Q9BW70, Q9Y5Y8	Gene names	LOXL2
Domain Architecture
Description	Lysyl oxidase homolog 2 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 2) (Lysyl oxidase-related protein 2) (Lysyl oxidase-related protein WS9-14).

LOXL2_MOUSE
θ value	1.32293e-51 (rank : 15)	NC score	0.819737 (rank : 13)
Query Neighborhood Hits	64	Target Neighborhood Hits	44	Shared Neighborhood Hits	32
SwissProt Accessions	P58022, Q8BRE6, Q8BS86, Q8C4K0, Q9JJ39	Gene names	Loxl2
Domain Architecture	No domain graphic available
Description	Lysyl oxidase homolog 2 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 2).

CD6_HUMAN
θ value	2.25659e-51 (rank : 16)	NC score	0.909177 (rank : 6)
Query Neighborhood Hits	64	Target Neighborhood Hits	65	Shared Neighborhood Hits	32
SwissProt Accessions	P30203, Q9UMF2, Q9Y4K7, Q9Y4K8, Q9Y4K9, Q9Y4L0	Gene names	CD6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor (T12) (TP120).

CD6_MOUSE
θ value	3.2585e-50 (rank : 17)	NC score	0.906584 (rank : 7)
Query Neighborhood Hits	64	Target Neighborhood Hits	62	Shared Neighborhood Hits	34
SwissProt Accessions	Q61003, Q60679, Q61004	Gene names	Cd6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor.

LG3BP_HUMAN
θ value	2.96777e-27 (rank : 18)	NC score	0.845448 (rank : 8)
Query Neighborhood Hits	64	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	Q08380	Gene names	LGALS3BP, M2BP
Domain Architecture
Description	Galectin-3-binding protein precursor (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (Mac-2 BP) (MAC2BP) (Tumor-associated antigen 90K).

MSRE_MOUSE
θ value	7.30988e-26 (rank : 19)	NC score	0.663774 (rank : 17)
Query Neighborhood Hits	64	Target Neighborhood Hits	307	Shared Neighborhood Hits	31
SwissProt Accessions	P30204, Q923G0, Q9QZ56	Gene names	Msr1, Scvr
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor type A) (SR-A).

MSRE_HUMAN
θ value	1.24688e-25 (rank : 20)	NC score	0.604899 (rank : 19)
Query Neighborhood Hits	64	Target Neighborhood Hits	298	Shared Neighborhood Hits	32
SwissProt Accessions	P21757, P21759, Q45F10	Gene names	MSR1, SCARA1
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor class A member 1) (CD204 antigen).

MARCO_HUMAN
θ value	3.62785e-25 (rank : 21)	NC score	0.520111 (rank : 21)
Query Neighborhood Hits	64	Target Neighborhood Hits	199	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UEW3, Q9Y5S3	Gene names	MARCO, SCARA2
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2).

MARCO_MOUSE
θ value	1.05554e-24 (rank : 22)	NC score	0.416670 (rank : 24)
Query Neighborhood Hits	64	Target Neighborhood Hits	242	Shared Neighborhood Hits	30
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

CD5_MOUSE
θ value	1.16975e-15 (rank : 23)	NC score	0.628729 (rank : 18)
Query Neighborhood Hits	64	Target Neighborhood Hits	33	Shared Neighborhood Hits	24
SwissProt Accessions	P13379	Gene names	Cd5, Ly-1
Domain Architecture
Description	T-cell surface glycoprotein CD5 precursor (Lymphocyte antigen Ly-1) (Lyt-1).

CD5_HUMAN
θ value	2.60593e-15 (rank : 24)	NC score	0.600161 (rank : 20)
Query Neighborhood Hits	64	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	P06127	Gene names	CD5, LEU1
Domain Architecture
Description	T-cell surface glycoprotein CD5 precursor (Lymphocyte antigen T1/Leu- 1).

CFAI_HUMAN
θ value	6.43352e-06 (rank : 25)	NC score	0.147363 (rank : 29)
Query Neighborhood Hits	64	Target Neighborhood Hits	289	Shared Neighborhood Hits	41
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CFAI_MOUSE
θ value	9.29e-05 (rank : 26)	NC score	0.144640 (rank : 30)
Query Neighborhood Hits	64	Target Neighborhood Hits	290	Shared Neighborhood Hits	40
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CORIN_MOUSE
θ value	0.000461057 (rank : 27)	NC score	0.089392 (rank : 38)
Query Neighborhood Hits	64	Target Neighborhood Hits	451	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

ENTK_HUMAN
θ value	0.00390308 (rank : 28)	NC score	0.125128 (rank : 34)
Query Neighborhood Hits	64	Target Neighborhood Hits	310	Shared Neighborhood Hits	42
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

TMPS3_HUMAN
θ value	0.00509761 (rank : 29)	NC score	0.112746 (rank : 35)
Query Neighborhood Hits	64	Target Neighborhood Hits	245	Shared Neighborhood Hits	41
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

TMPSD_MOUSE
θ value	0.00665767 (rank : 30)	NC score	0.105155 (rank : 37)
Query Neighborhood Hits	64	Target Neighborhood Hits	334	Shared Neighborhood Hits	38
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

ENTK_MOUSE
θ value	0.0113563 (rank : 31)	NC score	0.137955 (rank : 32)
Query Neighborhood Hits	64	Target Neighborhood Hits	338	Shared Neighborhood Hits	41
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

TMPS3_MOUSE
θ value	0.0193708 (rank : 32)	NC score	0.108751 (rank : 36)
Query Neighborhood Hits	64	Target Neighborhood Hits	239	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

TMPS2_HUMAN
θ value	0.0252991 (rank : 33)	NC score	0.086207 (rank : 42)
Query Neighborhood Hits	64	Target Neighborhood Hits	252	Shared Neighborhood Hits	33
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS2_MOUSE
θ value	0.0563607 (rank : 34)	NC score	0.076961 (rank : 57)
Query Neighborhood Hits	64	Target Neighborhood Hits	243	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS5_MOUSE
θ value	0.0736092 (rank : 35)	NC score	0.085760 (rank : 43)
Query Neighborhood Hits	64	Target Neighborhood Hits	185	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

GLUD1_MOUSE
θ value	0.125558 (rank : 36)	NC score	0.034145 (rank : 231)
Query Neighborhood Hits	64	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CIX8	Gene names	Gluld1, Lgs
Domain Architecture	No domain graphic available
Description	Glutamate--ammonia ligase domain-containing protein 1 (Lengsin) (Lens glutamine synthase-like).

TMPS5_HUMAN
θ value	0.279714 (rank : 37)	NC score	0.079272 (rank : 49)
Query Neighborhood Hits	64	Target Neighborhood Hits	181	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

CD248_HUMAN
θ value	0.365318 (rank : 38)	NC score	0.012381 (rank : 240)
Query Neighborhood Hits	64	Target Neighborhood Hits	679	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

TMPSD_HUMAN
θ value	0.365318 (rank : 39)	NC score	0.084187 (rank : 44)
Query Neighborhood Hits	64	Target Neighborhood Hits	333	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

CDYL_MOUSE
θ value	0.47712 (rank : 40)	NC score	0.014126 (rank : 237)
Query Neighborhood Hits	64	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WTK2	Gene names	Cdyl
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

S22A3_MOUSE
θ value	0.62314 (rank : 41)	NC score	0.011867 (rank : 241)
Query Neighborhood Hits	64	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WTW5, Q9R209	Gene names	Slc22a3, Oct3
Domain Architecture
Description	Organic cation transporter 3 (Solute carrier family 22 member 3).

LAMC1_MOUSE
θ value	0.813845 (rank : 42)	NC score	0.006827 (rank : 244)
Query Neighborhood Hits	64	Target Neighborhood Hits	856	Shared Neighborhood Hits	12
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LTBP2_MOUSE
θ value	0.813845 (rank : 43)	NC score	0.007273 (rank : 243)
Query Neighborhood Hits	64	Target Neighborhood Hits	617	Shared Neighborhood Hits	15
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

UROM_HUMAN
θ value	0.813845 (rank : 44)	NC score	0.045404 (rank : 230)
Query Neighborhood Hits	64	Target Neighborhood Hits	284	Shared Neighborhood Hits	16
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

CORIN_HUMAN
θ value	1.06291 (rank : 45)	NC score	0.075457 (rank : 59)
Query Neighborhood Hits	64	Target Neighborhood Hits	453	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

BAI3_HUMAN
θ value	1.81305 (rank : 46)	NC score	0.004149 (rank : 247)
Query Neighborhood Hits	64	Target Neighborhood Hits	246	Shared Neighborhood Hits	3
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

K0133_HUMAN
θ value	1.81305 (rank : 47)	NC score	0.021866 (rank : 233)
Query Neighborhood Hits	64	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q14146	Gene names	KIAA0133
Domain Architecture	No domain graphic available
Description	Protein KIAA0133.

TMPS4_MOUSE
θ value	1.81305 (rank : 48)	NC score	0.086315 (rank : 41)
Query Neighborhood Hits	64	Target Neighborhood Hits	210	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

SPG16_HUMAN
θ value	2.36792 (rank : 49)	NC score	0.002808 (rank : 250)
Query Neighborhood Hits	64	Target Neighborhood Hits	361	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N0X2, Q658W1, Q68DB3, Q6I9Z6, Q8N9C7, Q9H601	Gene names	SPAG16, PF20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

SYP2L_HUMAN
θ value	2.36792 (rank : 50)	NC score	0.008001 (rank : 242)
Query Neighborhood Hits	64	Target Neighborhood Hits	400	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

EXO1_MOUSE
θ value	3.0926 (rank : 51)	NC score	0.012624 (rank : 239)
Query Neighborhood Hits	64	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

K1267_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.016294 (rank : 236)
Query Neighborhood Hits	64	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z3B3, Q6AW85, Q8IYH1, Q9NTE7, Q9UFT0, Q9ULF3	Gene names	KIAA1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

LAMA2_MOUSE
θ value	4.03905 (rank : 53)	NC score	0.003265 (rank : 248)
Query Neighborhood Hits	64	Target Neighborhood Hits	1198	Shared Neighborhood Hits	16
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

AD26A_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.001917 (rank : 251)
Query Neighborhood Hits	64	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).

ATRN_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.032329 (rank : 232)
Query Neighborhood Hits	64	Target Neighborhood Hits	525	Shared Neighborhood Hits	13
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

C1RA_MOUSE
θ value	5.27518 (rank : 56)	NC score	0.076992 (rank : 56)
Query Neighborhood Hits	64	Target Neighborhood Hits	379	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

LRP1_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.017653 (rank : 234)
Query Neighborhood Hits	64	Target Neighborhood Hits	617	Shared Neighborhood Hits	29
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

HGFA_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.061209 (rank : 126)
Query Neighborhood Hits	64	Target Neighborhood Hits	436	Shared Neighborhood Hits	28
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

C1RB_MOUSE
θ value	8.99809 (rank : 59)	NC score	0.077422 (rank : 55)
Query Neighborhood Hits	64	Target Neighborhood Hits	380	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

CR1_HUMAN
θ value	8.99809 (rank : 60)	NC score	0.002888 (rank : 249)
Query Neighborhood Hits	64	Target Neighborhood Hits	108	Shared Neighborhood Hits	6
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

EGF_MOUSE
θ value	8.99809 (rank : 61)	NC score	0.004903 (rank : 246)
Query Neighborhood Hits	64	Target Neighborhood Hits	358	Shared Neighborhood Hits	12
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

K1267_MOUSE
θ value	8.99809 (rank : 62)	NC score	0.012937 (rank : 238)
Query Neighborhood Hits	64	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TG1, Q3TT88, Q3U5D8, Q3V3N3, Q7TMU3, Q80XP7, Q8R3L6, Q9D9G0	Gene names	Kiaa1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

LMA1L_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.005744 (rank : 245)
Query Neighborhood Hits	64	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCD3	Gene names	Lman1l, Ergl
Domain Architecture
Description	ERGIC-53-like protein precursor (ERGIC53-like protein) (Lectin, mannose-binding 1-like) (LMAN1-like protein).

LRP4_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.016460 (rank : 235)
Query Neighborhood Hits	64	Target Neighborhood Hits	351	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

ACRO_HUMAN
θ value	θ > 10 (rank : 65)	NC score	0.066915 (rank : 82)
Query Neighborhood Hits	64	Target Neighborhood Hits	291	Shared Neighborhood Hits	20
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

ACRO_MOUSE
θ value	θ > 10 (rank : 66)	NC score	0.067533 (rank : 76)
Query Neighborhood Hits	64	Target Neighborhood Hits	185	Shared Neighborhood Hits	20
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

APOA_HUMAN
θ value	θ > 10 (rank : 67)	NC score	0.057288 (rank : 163)
Query Neighborhood Hits	64	Target Neighborhood Hits	221	Shared Neighborhood Hits	20
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

BMP1_HUMAN
θ value	θ > 10 (rank : 68)	NC score	0.066413 (rank : 88)
Query Neighborhood Hits	64	Target Neighborhood Hits	233	Shared Neighborhood Hits	13
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.066618 (rank : 85)
Query Neighborhood Hits	64	Target Neighborhood Hits	236	Shared Neighborhood Hits	13
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BSSP4_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.062918 (rank : 116)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

BSSP4_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.062716 (rank : 119)
Query Neighborhood Hits	64	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

C1R_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.077684 (rank : 53)
Query Neighborhood Hits	64	Target Neighborhood Hits	364	Shared Neighborhood Hits	29
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

C1S_HUMAN
θ value	θ > 10 (rank : 73)	NC score	0.079708 (rank : 46)
Query Neighborhood Hits	64	Target Neighborhood Hits	359	Shared Neighborhood Hits	28
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CATG_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.052855 (rank : 200)
Query Neighborhood Hits	64	Target Neighborhood Hits	174	Shared Neighborhood Hits	20
SwissProt Accessions	P08311	Gene names	CTSG
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (CG).

CATG_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.053493 (rank : 193)
Query Neighborhood Hits	64	Target Neighborhood Hits	174	Shared Neighborhood Hits	20
SwissProt Accessions	P28293	Gene names	Ctsg
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (Vimentin-specific protease) (VSP).

CFAD_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.057672 (rank : 159)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

CFAD_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.058560 (rank : 149)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

CLCR_HUMAN
θ value	θ > 10 (rank : 78)	NC score	0.062887 (rank : 117)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

CS1A_MOUSE
θ value	θ > 10 (rank : 79)	NC score	0.079679 (rank : 47)
Query Neighborhood Hits	64	Target Neighborhood Hits	360	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.080657 (rank : 45)
Query Neighborhood Hits	64	Target Neighborhood Hits	361	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CSMD1_MOUSE
θ value	θ > 10 (rank : 81)	NC score	0.050216 (rank : 225)
Query Neighborhood Hits	64	Target Neighborhood Hits	193	Shared Neighborhood Hits	12
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD2_HUMAN
θ value	θ > 10 (rank : 82)	NC score	0.058759 (rank : 147)
Query Neighborhood Hits	64	Target Neighborhood Hits	188	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD3_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.051508 (rank : 216)
Query Neighborhood Hits	64	Target Neighborhood Hits	199	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CTRB1_HUMAN
θ value	θ > 10 (rank : 84)	NC score	0.061509 (rank : 125)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

CTRL_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.062026 (rank : 122)
Query Neighborhood Hits	64	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

CUBN_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.054031 (rank : 187)
Query Neighborhood Hits	64	Target Neighborhood Hits	482	Shared Neighborhood Hits	18
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.053094 (rank : 197)
Query Neighborhood Hits	64	Target Neighborhood Hits	477	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CUZD1_HUMAN
θ value	θ > 10 (rank : 88)	NC score	0.134722 (rank : 33)
Query Neighborhood Hits	64	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUZD1_MOUSE
θ value	θ > 10 (rank : 89)	NC score	0.139080 (rank : 31)
Query Neighborhood Hits	64	Target Neighborhood Hits	91	Shared Neighborhood Hits	8
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

DCBD2_HUMAN
θ value	θ > 10 (rank : 90)	NC score	0.051266 (rank : 219)
Query Neighborhood Hits	64	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DESC4_MOUSE
θ value	θ > 10 (rank : 91)	NC score	0.065661 (rank : 94)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

EGFB2_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.051975 (rank : 210)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	P36368, P00754	Gene names	Egfbp2, Egfbp-2, Klk-13, Klk13
Domain Architecture
Description	Epidermal growth factor-binding protein type B precursor (EC 3.4.21.35) (EGF-BP B) (Glandular kallikrein K13) (Tissue kallikrein 13) (mGK-13) (Prorenin-converting enzyme) (PRECE).

ELA1_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.060785 (rank : 132)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UNI1, Q5MLF0, Q6DJT0, Q6ISM6	Gene names	ELA1
Domain Architecture
Description	Elastase-1 precursor (EC 3.4.21.36).

ELA2A_HUMAN
θ value	θ > 10 (rank : 94)	NC score	0.060818 (rank : 131)
Query Neighborhood Hits	64	Target Neighborhood Hits	180	Shared Neighborhood Hits	20
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

ELA2A_MOUSE
θ value	θ > 10 (rank : 95)	NC score	0.060724 (rank : 134)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

ELA2B_HUMAN
θ value	θ > 10 (rank : 96)	NC score	0.060449 (rank : 136)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

ELA3A_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.060311 (rank : 137)
Query Neighborhood Hits	64	Target Neighborhood Hits	173	Shared Neighborhood Hits	20
SwissProt Accessions	P09093, Q9BRW4	Gene names	ELA3A, ELA3
Domain Architecture
Description	Elastase-3A precursor (EC 3.4.21.70) (Elastase IIIA) (Protease E).

ELA3B_HUMAN
θ value	θ > 10 (rank : 98)	NC score	0.059710 (rank : 141)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

ELNE_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.052855 (rank : 201)
Query Neighborhood Hits	64	Target Neighborhood Hits	164	Shared Neighborhood Hits	20
SwissProt Accessions	P08246, P09649, Q6B0D9, Q6LDP5	Gene names	ELA2
Domain Architecture
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase) (PMN elastase) (Bone marrow serine protease) (Medullasin) (Human leukocyte elastase) (HLE).

ELNE_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.054132 (rank : 184)
Query Neighborhood Hits	64	Target Neighborhood Hits	167	Shared Neighborhood Hits	20
SwissProt Accessions	Q3UP87, Q61515	Gene names	Ela2
Domain Architecture	No domain graphic available
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase).

FA10_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.059225 (rank : 144)
Query Neighborhood Hits	64	Target Neighborhood Hits	431	Shared Neighborhood Hits	27
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA10_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.058687 (rank : 148)
Query Neighborhood Hits	64	Target Neighborhood Hits	435	Shared Neighborhood Hits	27
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA11_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.065603 (rank : 95)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA11_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.064588 (rank : 105)
Query Neighborhood Hits	64	Target Neighborhood Hits	180	Shared Neighborhood Hits	20
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

FA12_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.059925 (rank : 139)
Query Neighborhood Hits	64	Target Neighborhood Hits	425	Shared Neighborhood Hits	27
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA7_HUMAN
θ value	θ > 10 (rank : 106)	NC score	0.058318 (rank : 153)
Query Neighborhood Hits	64	Target Neighborhood Hits	404	Shared Neighborhood Hits	27
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FA7_MOUSE
θ value	θ > 10 (rank : 107)	NC score	0.059213 (rank : 145)
Query Neighborhood Hits	64	Target Neighborhood Hits	374	Shared Neighborhood Hits	25
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FA9_HUMAN
θ value	θ > 10 (rank : 108)	NC score	0.055123 (rank : 175)
Query Neighborhood Hits	64	Target Neighborhood Hits	421	Shared Neighborhood Hits	27
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

GP2_MOUSE
θ value	θ > 10 (rank : 109)	NC score	0.060772 (rank : 133)
Query Neighborhood Hits	64	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D733	Gene names	Gp2
Domain Architecture	No domain graphic available
Description	Pancreatic secretory granule membrane major glycoprotein GP2 precursor (Pancreatic zymogen granule membrane protein GP-2).

GRAC_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.050192 (rank : 226)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P08882, Q61389	Gene names	Gzmc, Ctla-5, Ctla5
Domain Architecture
Description	Granzyme C precursor (EC 3.4.21.-) (Cytotoxic cell protease 2) (CCP2) (B10).

GRAD_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.050560 (rank : 222)
Query Neighborhood Hits	64	Target Neighborhood Hits	173	Shared Neighborhood Hits	20
SwissProt Accessions	P11033, P97387	Gene names	Gzmd
Domain Architecture
Description	Granzyme D precursor (EC 3.4.21.-).

GRAE_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.051244 (rank : 220)
Query Neighborhood Hits	64	Target Neighborhood Hits	172	Shared Neighborhood Hits	20
SwissProt Accessions	P08884, P97389	Gene names	Gzme, Ccp3, Ctla-6, Ctla6
Domain Architecture
Description	Granzyme E precursor (EC 3.4.21.-) (Cytotoxic cell protease 3) (CCP3) (CTL serine protease 2) (D12) (Cytotoxic serine protease 2) (MCSP2).

GRAF_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.051505 (rank : 217)
Query Neighborhood Hits	64	Target Neighborhood Hits	172	Shared Neighborhood Hits	20
SwissProt Accessions	P08883	Gene names	Gzmf, Ccp4, Ctla-7, Ctla7
Domain Architecture
Description	Granzyme F precursor (EC 3.4.21.-) (Cytotoxic cell protease 4) (CCP4) (CTL serine protease 3) (C134) (Cytotoxic serine protease 3) (MCSP3).

GRAG_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.051407 (rank : 218)
Query Neighborhood Hits	64	Target Neighborhood Hits	173	Shared Neighborhood Hits	20
SwissProt Accessions	P13366, P97388	Gene names	Gzmg
Domain Architecture
Description	Granzyme G precursor (EC 3.4.21.-) (CTL serine protease 1) (MCSP-1).

GRAH_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.050667 (rank : 221)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

GRAK_MOUSE
θ value	θ > 10 (rank : 116)	NC score	0.056051 (rank : 172)
Query Neighborhood Hits	64	Target Neighborhood Hits	174	Shared Neighborhood Hits	20
SwissProt Accessions	O35205	Gene names	Gzmk
Domain Architecture
Description	Granzyme K precursor (EC 3.4.21.-).

GRAM_HUMAN
θ value	θ > 10 (rank : 117)	NC score	0.054905 (rank : 177)
Query Neighborhood Hits	64	Target Neighborhood Hits	174	Shared Neighborhood Hits	20
SwissProt Accessions	P51124	Gene names	GZMM, MET1
Domain Architecture
Description	Granzyme M precursor (EC 3.4.21.-) (Met-ase) (Natural killer cell granular protease) (HU-Met-1) (Met-1 serine protease).

HABP2_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.058498 (rank : 150)
Query Neighborhood Hits	64	Target Neighborhood Hits	431	Shared Neighborhood Hits	27
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HABP2_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.058138 (rank : 155)
Query Neighborhood Hits	64	Target Neighborhood Hits	445	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

HEPS_HUMAN
θ value	θ > 10 (rank : 120)	NC score	0.067708 (rank : 75)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HEPS_MOUSE
θ value	θ > 10 (rank : 121)	NC score	0.067141 (rank : 79)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	22
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

HGFA_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.059587 (rank : 142)
Query Neighborhood Hits	64	Target Neighborhood Hits	419	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

HGFL_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.054416 (rank : 181)
Query Neighborhood Hits	64	Target Neighborhood Hits	190	Shared Neighborhood Hits	20
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HGFL_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.054424 (rank : 180)
Query Neighborhood Hits	64	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HGF_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.053566 (rank : 192)
Query Neighborhood Hits	64	Target Neighborhood Hits	191	Shared Neighborhood Hits	20
SwissProt Accessions	P14210, Q02935, Q13494, Q14519, Q8TCE2, Q9BYL9, Q9BYM0, Q9UDU6	Gene names	HGF, HPTA
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

HGF_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.053120 (rank : 195)
Query Neighborhood Hits	64	Target Neighborhood Hits	192	Shared Neighborhood Hits	20
SwissProt Accessions	Q08048, Q61662, Q64007, Q6LBE6	Gene names	Hgf
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

HPTR_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.056971 (rank : 167)
Query Neighborhood Hits	64	Target Neighborhood Hits	166	Shared Neighborhood Hits	20
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

HPT_HUMAN
θ value	θ > 10 (rank : 128)	NC score	0.057037 (rank : 164)
Query Neighborhood Hits	64	Target Neighborhood Hits	184	Shared Neighborhood Hits	21
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

HPT_MOUSE
θ value	θ > 10 (rank : 129)	NC score	0.056960 (rank : 168)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

K1B11_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.053971 (rank : 189)
Query Neighborhood Hits	64	Target Neighborhood Hits	180	Shared Neighborhood Hits	20
SwissProt Accessions	P15946	Gene names	Klk1b11, Klk-11, Klk11
Domain Architecture
Description	Kallikrein 1-related peptidase b11 precursor (EC 3.4.21.35) (Tissue kallikrein-11) (Glandular kallikrein K11) (mGK-11).

K1B21_MOUSE
θ value	θ > 10 (rank : 131)	NC score	0.051836 (rank : 212)
Query Neighborhood Hits	64	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	Q61759, Q61760, Q9JM70	Gene names	Klk1b21, Klk-21, Klk21
Domain Architecture
Description	Kallikrein 1-related peptidase b21 precursor (EC 3.4.21.35) (Tissue kallikrein 21) (Glandular kallikrein K21) (mGK-21).

K1B22_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.051518 (rank : 215)
Query Neighborhood Hits	64	Target Neighborhood Hits	174	Shared Neighborhood Hits	20
SwissProt Accessions	P15948	Gene names	Klk1b22, Klk-22, Klk22
Domain Architecture
Description	Kallikrein 1-related peptidase b22 precursor (EC 3.4.21.35) (Glandular kallikrein K22) (Tissue kallikrein 22) (mGK-22) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Nerve growth factor beta chain endopeptidase) (Beta-NGF-endopeptidase).

K1B24_MOUSE
θ value	θ > 10 (rank : 133)	NC score	0.052824 (rank : 202)
Query Neighborhood Hits	64	Target Neighborhood Hits	180	Shared Neighborhood Hits	20
SwissProt Accessions	Q61754, Q61755, Q9JM69	Gene names	Klk1b24, Klk-24, Klk24
Domain Architecture
Description	Kallikrein 1-related peptidase b24 precursor (EC 3.4.21.35) (Glandular kallikrein K24) (Tissue kallikrein 24) (mGK-24).

K1B26_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.052525 (rank : 206)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P36369, P00753, P00754	Gene names	Klk1b26, Klk-26, Klk26
Domain Architecture
Description	Kallikrein 1-related peptidase b26 precursor (EC 3.4.21.35) (Glandular kallikrein K26) (Tissue kallikrein 26) (mGK-26) (Prorenin-converting enzyme 2) (PRECE-2).

K1B27_MOUSE
θ value	θ > 10 (rank : 135)	NC score	0.052662 (rank : 205)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JM71	Gene names	Klk1b27, Klk-27, Klk27
Domain Architecture
Description	Kallikrein 1-related peptidase b27 precursor (EC 3.4.21.-) (Tissue kallikrein 27) (Glandular kallikrein K27) (mGK-27) (mKlk27).

K1KB1_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.054124 (rank : 185)
Query Neighborhood Hits	64	Target Neighborhood Hits	180	Shared Neighborhood Hits	20
SwissProt Accessions	P00755	Gene names	Klk1b1, Klk-1, Klk1
Domain Architecture
Description	Kallikrein 1-related peptidase b1 precursor (EC 3.4.21.35) (Glandular kallikrein K1) (Tissue kallikrein-1) (mGK-1).

K1KB3_MOUSE
θ value	θ > 10 (rank : 137)	NC score	0.052761 (rank : 203)
Query Neighborhood Hits	64	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	P00756	Gene names	Klk1b3, Klk-3, Klk3, Ngfg
Domain Architecture
Description	Kallikrein 1-related peptidase b3 precursor (EC 3.4.21.35) (Glandular kallikrein K3) (Tissue kallikrein-3) (mGK-3) (7S nerve growth factor gamma chain) (Gamma-NGF) [Contains: Nerve growth factor gamma chain 1; Nerve growth factor gamma chain 2].

K1KB4_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.050431 (rank : 223)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P00757	Gene names	Klk1b4, Klk-4, Klk4, Ngfa
Domain Architecture
Description	Kallikrein 1-related peptidase-like b4 precursor (7S nerve growth factor alpha chain) (Alpha-NGF).

K1KB5_MOUSE
θ value	θ > 10 (rank : 139)	NC score	0.052100 (rank : 209)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P15945, Q52KM1, Q565D7	Gene names	Klk1b5, Klk-5, Klk5
Domain Architecture
Description	Kallikrein 1-related peptidase b5 precursor (EC 3.4.21.35) (Glandular kallikrein K5) (Tissue kallikrein-5) (mGK-5).

K1KB8_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.051522 (rank : 214)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P07628	Gene names	Klk1b8, Klk-8, Klk8
Domain Architecture
Description	Kallikrein 1-related peptidase b8 precursor (EC 3.4.21.35) (Tissue kallikrein-8) (Glandular kallikrein K8) (mGK-8).

K1KB9_MOUSE
θ value	θ > 10 (rank : 141)	NC score	0.052907 (rank : 199)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

KLK10_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.057986 (rank : 157)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	O43240, Q99920, Q9GZW9	Gene names	KLK10, NES1, PRRSL1
Domain Architecture
Description	Kallikrein-10 precursor (EC 3.4.21.-) (Protease serine-like 1) (Normal epithelial cell-specific 1).

KLK11_HUMAN
θ value	θ > 10 (rank : 143)	NC score	0.053767 (rank : 191)
Query Neighborhood Hits	64	Target Neighborhood Hits	174	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UBX7, O75837, Q9NS65	Gene names	KLK11, PRSS20, TLSP
Domain Architecture
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin) (Trypsin-like protease).

KLK11_MOUSE
θ value	θ > 10 (rank : 144)	NC score	0.053772 (rank : 190)
Query Neighborhood Hits	64	Target Neighborhood Hits	174	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QYN3, Q9QYN4	Gene names	Klk11, Prss20
Domain Architecture	No domain graphic available
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin).

KLK12_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.054457 (rank : 179)
Query Neighborhood Hits	64	Target Neighborhood Hits	197	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKR0, Q9UKR1	Gene names	KLK12, KLKL5
Domain Architecture
Description	Kallikrein-12 precursor (EC 3.4.21.-) (Kallikrein-like protein 5) (KLK-L5).

KLK13_HUMAN
θ value	θ > 10 (rank : 146)	NC score	0.057493 (rank : 161)
Query Neighborhood Hits	64	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

KLK14_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.054162 (rank : 183)
Query Neighborhood Hits	64	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

KLK15_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.054954 (rank : 176)
Query Neighborhood Hits	64	Target Neighborhood Hits	180	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

KLK1_HUMAN
θ value	θ > 10 (rank : 149)	NC score	0.050140 (rank : 227)
Query Neighborhood Hits	64	Target Neighborhood Hits	183	Shared Neighborhood Hits	20
SwissProt Accessions	P06870, Q8TCV8, Q9BS53, Q9NQU4, Q9UMJ1	Gene names	KLK1
Domain Architecture
Description	Kallikrein-1 precursor (EC 3.4.21.35) (Tissue kallikrein) (Kidney/pancreas/salivary gland kallikrein).

KLK1_MOUSE
θ value	θ > 10 (rank : 150)	NC score	0.052344 (rank : 208)
Query Neighborhood Hits	64	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	P15947, Q61855	Gene names	Klk1, Klk-6, Klk6
Domain Architecture
Description	Glandular kallikrein K1 precursor (EC 3.4.21.35) (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B).

KLK2_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.051572 (rank : 213)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	P20151, Q15946, Q9UJZ9	Gene names	KLK2
Domain Architecture
Description	Kallikrein-2 precursor (EC 3.4.21.35) (Tissue kallikrein-2) (Glandular kallikrein-1) (hGK-1).

KLK4_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.052432 (rank : 207)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

KLK5_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.053047 (rank : 198)
Query Neighborhood Hits	64	Target Neighborhood Hits	182	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y337, Q9HBG8	Gene names	KLK5, SCTE
Domain Architecture
Description	Kallikrein-5 precursor (EC 3.4.21.-) (Stratum corneum tryptic enzyme) (Kallikrein-like protein 2) (KLK-L2).

KLK6_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.058005 (rank : 156)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

KLK7_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.054170 (rank : 182)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	P49862, Q8N5N9, Q8NFV7	Gene names	KLK7, PRSS6, SCCE
Domain Architecture
Description	Kallikrein-7 precursor (EC 3.4.21.-) (hK7) (Stratum corneum chymotryptic enzyme) (hSCCE).

KLK7_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.055350 (rank : 174)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

KLK9_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.053975 (rank : 188)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKQ9	Gene names	KLK9
Domain Architecture
Description	Kallikrein-9 precursor (EC 3.4.21.-) (Kallikrein-like protein 3) (KLK- L3).

KLKB1_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.063910 (rank : 111)
Query Neighborhood Hits	64	Target Neighborhood Hits	183	Shared Neighborhood Hits	20
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KLKB1_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.065009 (rank : 103)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

KREM1_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.054034 (rank : 186)
Query Neighborhood Hits	64	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM1_MOUSE
θ value	θ > 10 (rank : 161)	NC score	0.057032 (rank : 165)
Query Neighborhood Hits	64	Target Neighborhood Hits	92	Shared Neighborhood Hits	10
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

LOXL1_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.265209 (rank : 27)
Query Neighborhood Hits	64	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q08397, Q96BW7	Gene names	LOXL1, LOXL
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (LOL).

LOXL1_MOUSE
θ value	θ > 10 (rank : 163)	NC score	0.264283 (rank : 28)
Query Neighborhood Hits	64	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	P97873, Q91ZY4, Q99KX3	Gene names	Loxl1, Lox2, Loxl
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (Lysyl oxidase 2).

LRP12_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.070667 (rank : 66)
Query Neighborhood Hits	64	Target Neighborhood Hits	205	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.070602 (rank : 67)
Query Neighborhood Hits	64	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP3_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.053098 (rank : 196)
Query Neighborhood Hits	64	Target Neighborhood Hits	280	Shared Neighborhood Hits	21
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LYOX_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.278744 (rank : 25)
Query Neighborhood Hits	64	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P28300, Q5FWF0	Gene names	LOX
Domain Architecture
Description	Protein-lysine 6-oxidase precursor (EC 1.4.3.13) (Lysyl oxidase).

LYOX_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.276626 (rank : 26)
Query Neighborhood Hits	64	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	P28301	Gene names	Lox, Rrg
Domain Architecture
Description	Protein-lysine 6-oxidase precursor (EC 1.4.3.13) (Lysyl oxidase) (RAS excision protein).

MASP1_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.079669 (rank : 48)
Query Neighborhood Hits	64	Target Neighborhood Hits	369	Shared Neighborhood Hits	30
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.078923 (rank : 51)
Query Neighborhood Hits	64	Target Neighborhood Hits	364	Shared Neighborhood Hits	29
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MASP2_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.078959 (rank : 50)
Query Neighborhood Hits	64	Target Neighborhood Hits	364	Shared Neighborhood Hits	29
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.075389 (rank : 60)
Query Neighborhood Hits	64	Target Neighborhood Hits	382	Shared Neighborhood Hits	29
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MCPT1_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.053437 (rank : 194)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P11034	Gene names	Mcpt1
Domain Architecture
Description	Mast cell protease 1 precursor (EC 3.4.21.-) (MMCP-1).

MCPT2_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.050033 (rank : 228)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	P15119	Gene names	Mcpt2
Domain Architecture
Description	Mast cell protease 2 precursor (EC 3.4.21.-) (MMCP-2).

MCPT4_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.052675 (rank : 204)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	P21812, Q9EPQ9, Q9EQT2	Gene names	Mcpt4
Domain Architecture
Description	Mast cell protease 4 precursor (EC 3.4.21.-) (MMCP-4) (Serosal mast cell protease) (MSMCP) (Myonase).

MCPT6_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.061842 (rank : 124)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

MFRP_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.067293 (rank : 77)
Query Neighborhood Hits	64	Target Neighborhood Hits	165	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.068170 (rank : 74)
Query Neighborhood Hits	64	Target Neighborhood Hits	166	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NETO1_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.065265 (rank : 100)
Query Neighborhood Hits	64	Target Neighborhood Hits	110	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.064491 (rank : 106)
Query Neighborhood Hits	64	Target Neighborhood Hits	109	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.066348 (rank : 89)
Query Neighborhood Hits	64	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.066578 (rank : 86)
Query Neighborhood Hits	64	Target Neighborhood Hits	113	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NRP2_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.050028 (rank : 229)
Query Neighborhood Hits	64	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRPN_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.055999 (rank : 173)
Query Neighborhood Hits	64	Target Neighborhood Hits	182	Shared Neighborhood Hits	20
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

NRPN_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.056725 (rank : 171)
Query Neighborhood Hits	64	Target Neighborhood Hits	186	Shared Neighborhood Hits	20
SwissProt Accessions	Q61955	Gene names	Klk8, Nrpn, Prss19
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8).

PCOC1_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.065830 (rank : 93)
Query Neighborhood Hits	64	Target Neighborhood Hits	146	Shared Neighborhood Hits	6
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.067242 (rank : 78)
Query Neighborhood Hits	64	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.072720 (rank : 63)
Query Neighborhood Hits	64	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.073592 (rank : 62)
Query Neighborhood Hits	64	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PLMN_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.058167 (rank : 154)
Query Neighborhood Hits	64	Target Neighborhood Hits	204	Shared Neighborhood Hits	20
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

PLMN_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.058339 (rank : 151)
Query Neighborhood Hits	64	Target Neighborhood Hits	208	Shared Neighborhood Hits	20
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

POLS2_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.062105 (rank : 121)
Query Neighborhood Hits	64	Target Neighborhood Hits	192	Shared Neighborhood Hits	20
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

POLS2_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.060713 (rank : 135)
Query Neighborhood Hits	64	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

PROC_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.059887 (rank : 140)
Query Neighborhood Hits	64	Target Neighborhood Hits	406	Shared Neighborhood Hits	27
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROC_MOUSE
θ value	θ > 10 (rank : 195)	NC score	0.058325 (rank : 152)
Query Neighborhood Hits	64	Target Neighborhood Hits	426	Shared Neighborhood Hits	28
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PRS27_HUMAN
θ value	θ > 10 (rank : 196)	NC score	0.062883 (rank : 118)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

PRS27_MOUSE
θ value	θ > 10 (rank : 197)	NC score	0.063270 (rank : 115)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

PRSS8_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.061202 (rank : 127)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

PRSS8_MOUSE
θ value	θ > 10 (rank : 199)	NC score	0.062170 (rank : 120)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

PRTN3_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.051852 (rank : 211)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	P24158, P15637, P18078, Q6LBM7, Q9UQD8	Gene names	PRTN3, MBN
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Leukocyte proteinase 3) (PR-3) (PR3) (AGP7) (Wegener autoantigen) (P29) (C-ANCA antigen) (Neutrophil proteinase 4) (NP-4).

ST14_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.086878 (rank : 40)
Query Neighborhood Hits	64	Target Neighborhood Hits	409	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ST14_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.089322 (rank : 39)
Query Neighborhood Hits	64	Target Neighborhood Hits	419	Shared Neighborhood Hits	27
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

TECTA_MOUSE
θ value	θ > 10 (rank : 203)	NC score	0.050289 (rank : 224)
Query Neighborhood Hits	64	Target Neighborhood Hits	244	Shared Neighborhood Hits	13
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TECTB_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.068218 (rank : 72)
Query Neighborhood Hits	64	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q96PL2	Gene names	TECTB
Domain Architecture
Description	Beta-tectorin precursor.

TECTB_MOUSE
θ value	θ > 10 (rank : 205)	NC score	0.068276 (rank : 71)
Query Neighborhood Hits	64	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	O08524	Gene names	Tectb
Domain Architecture
Description	Beta-tectorin precursor.

TEST_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.066502 (rank : 87)
Query Neighborhood Hits	64	Target Neighborhood Hits	172	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

TEST_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.063441 (rank : 113)
Query Neighborhood Hits	64	Target Neighborhood Hits	174	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

TGBR3_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.066890 (rank : 83)
Query Neighborhood Hits	64	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q03167, Q5T2T4, Q5U731, Q9UGI2	Gene names	TGFBR3
Domain Architecture
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

TGBR3_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.065162 (rank : 102)
Query Neighborhood Hits	64	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	O88393, Q6NS72	Gene names	Tgfbr3
Domain Architecture	No domain graphic available
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

THRB_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.057885 (rank : 158)
Query Neighborhood Hits	64	Target Neighborhood Hits	196	Shared Neighborhood Hits	20
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

THRB_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.056941 (rank : 169)
Query Neighborhood Hits	64	Target Neighborhood Hits	195	Shared Neighborhood Hits	20
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

TLL1_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.071028 (rank : 65)
Query Neighborhood Hits	64	Target Neighborhood Hits	236	Shared Neighborhood Hits	14
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.071992 (rank : 64)
Query Neighborhood Hits	64	Target Neighborhood Hits	237	Shared Neighborhood Hits	14
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.069020 (rank : 70)
Query Neighborhood Hits	64	Target Neighborhood Hits	241	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.069581 (rank : 69)
Query Neighborhood Hits	64	Target Neighborhood Hits	240	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TM11D_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.065509 (rank : 97)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11D_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.065907 (rank : 92)
Query Neighborhood Hits	64	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11E_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.066701 (rank : 84)
Query Neighborhood Hits	64	Target Neighborhood Hits	181	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TM11E_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.065420 (rank : 98)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TMPS4_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.074160 (rank : 61)
Query Neighborhood Hits	64	Target Neighborhood Hits	203	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

TMPS6_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.066150 (rank : 90)
Query Neighborhood Hits	64	Target Neighborhood Hits	338	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS6_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.065298 (rank : 99)
Query Neighborhood Hits	64	Target Neighborhood Hits	341	Shared Neighborhood Hits	24
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS7_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.078382 (rank : 52)
Query Neighborhood Hits	64	Target Neighborhood Hits	275	Shared Neighborhood Hits	25
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS7_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.075471 (rank : 58)
Query Neighborhood Hits	64	Target Neighborhood Hits	275	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS9_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.064181 (rank : 107)
Query Neighborhood Hits	64	Target Neighborhood Hits	276	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

TMPS9_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.063849 (rank : 112)
Query Neighborhood Hits	64	Target Neighborhood Hits	296	Shared Neighborhood Hits	22
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TMSP8_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.065207 (rank : 101)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

TPA_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.064117 (rank : 108)
Query Neighborhood Hits	64	Target Neighborhood Hits	324	Shared Neighborhood Hits	23
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TPA_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.065593 (rank : 96)
Query Neighborhood Hits	64	Target Neighborhood Hits	335	Shared Neighborhood Hits	26
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TRY1_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.057019 (rank : 166)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

TRY2_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.056834 (rank : 170)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

TRY2_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.057588 (rank : 160)
Query Neighborhood Hits	64	Target Neighborhood Hits	174	Shared Neighborhood Hits	20
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

TRY3_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.057421 (rank : 162)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

TRYA1_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.060935 (rank : 130)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

TRYB1_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.060992 (rank : 128)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB1_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.059994 (rank : 138)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

TRYB2_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.060992 (rank : 129)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

TRYD_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.059188 (rank : 146)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

TRYG1_HUMAN
θ value	θ > 10 (rank : 239)	NC score	0.063985 (rank : 110)
Query Neighborhood Hits	64	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TRYG1_MOUSE
θ value	θ > 10 (rank : 240)	NC score	0.064684 (rank : 104)
Query Neighborhood Hits	64	Target Neighborhood Hits	181	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

TSG6_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.067128 (rank : 80)
Query Neighborhood Hits	64	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.067053 (rank : 81)
Query Neighborhood Hits	64	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSP50_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.066103 (rank : 91)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

UROK_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.064094 (rank : 109)
Query Neighborhood Hits	64	Target Neighborhood Hits	272	Shared Neighborhood Hits	22
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

UROK_MOUSE
θ value	θ > 10 (rank : 245)	NC score	0.061944 (rank : 123)
Query Neighborhood Hits	64	Target Neighborhood Hits	273	Shared Neighborhood Hits	22
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

ZP1_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.054631 (rank : 178)
Query Neighborhood Hits	64	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q62005, Q62016	Gene names	Zp1
Domain Architecture
Description	Zona pellucida sperm-binding protein 1 precursor (Zona pellucida glycoprotein 1) (Zp-1).

ZP2_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.077594 (rank : 54)
Query Neighborhood Hits	64	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q05996	Gene names	ZP2, ZPA
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

ZP2_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.070380 (rank : 68)
Query Neighborhood Hits	64	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	P20239	Gene names	Zp2, Zp-2, Zpa
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

ZP3_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.059487 (rank : 143)
Query Neighborhood Hits	64	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	P21754, Q06633	Gene names	ZP3, ZP3A, ZPC
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 precursor (Zona pellucida glycoprotein ZP3) (Zona pellucida protein C) (Sperm receptor) (ZP3A/ZP3B).

ZP3_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.063380 (rank : 114)
Query Neighborhood Hits	64	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P10761	Gene names	Zp3, Zp-3, Zpc
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 precursor (Zona pellucida glycoprotein ZP3) (Sperm receptor) (Zona pellucida protein C).

ZP4_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.068179 (rank : 73)
Query Neighborhood Hits	64	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q12836	Gene names	ZP4, ZPB
Domain Architecture
Description	Zona pellucida sperm-binding protein 4 precursor (Zona pellucida sperm-binding protein B).

Hits sorted by NC score

C163B_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 3)
Query Neighborhood Hits	64	Target Neighborhood Hits	64	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

C163A_HUMAN
NC score	0.991627 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	64	Target Neighborhood Hits	54	Shared Neighborhood Hits	36
SwissProt Accessions	Q86VB7, Q07898, Q07899, Q07900, Q07901, Q2VLH7	Gene names	CD163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) (Hemoglobin scavenger receptor) [Contains: Soluble CD163 (sCD163)].

C163A_MOUSE
NC score	0.991469 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	64	Target Neighborhood Hits	48	Shared Neighborhood Hits	36
SwissProt Accessions	Q2VLH6, Q2VLH5, Q99MX8	Gene names	Cd163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) [Contains: Soluble CD163 (sCD163)].

CD5L_HUMAN
NC score	0.950819 (rank : 4)	θ value	1.27248e-70 (rank : 7)
Query Neighborhood Hits	64	Target Neighborhood Hits	45	Shared Neighborhood Hits	37
SwissProt Accessions	O43866, Q6UX63	Gene names	CD5L
Domain Architecture
Description	CD5 antigen-like precursor (SP-alpha) (CT-2) (IgM-associated peptide).

CD5L_MOUSE
NC score	0.949563 (rank : 5)	θ value	2.24614e-67 (rank : 9)
Query Neighborhood Hits	64	Target Neighborhood Hits	49	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QWK4, O35300, O35301, Q505P6, Q91W05	Gene names	Cd5l, Aim, Api6
Domain Architecture
Description	CD5 antigen-like precursor (SP-alpha) (CT-2) (Apoptosis inhibitory 6) (Apoptosis inhibitor expressed by macrophages).

CD6_HUMAN
NC score	0.909177 (rank : 6)	θ value	2.25659e-51 (rank : 16)
Query Neighborhood Hits	64	Target Neighborhood Hits	65	Shared Neighborhood Hits	32
SwissProt Accessions	P30203, Q9UMF2, Q9Y4K7, Q9Y4K8, Q9Y4K9, Q9Y4L0	Gene names	CD6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor (T12) (TP120).

CD6_MOUSE
NC score	0.906584 (rank : 7)	θ value	3.2585e-50 (rank : 17)
Query Neighborhood Hits	64	Target Neighborhood Hits	62	Shared Neighborhood Hits	34
SwissProt Accessions	Q61003, Q60679, Q61004	Gene names	Cd6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor.

LG3BP_HUMAN
NC score	0.845448 (rank : 8)	θ value	2.96777e-27 (rank : 18)
Query Neighborhood Hits	64	Target Neighborhood Hits	67	Shared Neighborhood Hits	30
SwissProt Accessions	Q08380	Gene names	LGALS3BP, M2BP
Domain Architecture
Description	Galectin-3-binding protein precursor (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (Mac-2 BP) (MAC2BP) (Tumor-associated antigen 90K).

LOXL4_MOUSE
NC score	0.823247 (rank : 9)	θ value	5.0155e-59 (rank : 11)
Query Neighborhood Hits	64	Target Neighborhood Hits	50	Shared Neighborhood Hits	33
SwissProt Accessions	Q924C6	Gene names	Loxl4, Loxc
Domain Architecture
Description	Lysyl oxidase homolog 4 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 4) (Lysyl oxidase-related protein C).

LOXL4_HUMAN
NC score	0.822786 (rank : 10)	θ value	2.7521e-57 (rank : 13)
Query Neighborhood Hits	64	Target Neighborhood Hits	43	Shared Neighborhood Hits	35
SwissProt Accessions	Q96JB6, Q96DY1, Q96PC0, Q9H6T5	Gene names	LOXL4, LOXC
Domain Architecture
Description	Lysyl oxidase homolog 4 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 4) (Lysyl oxidase-related protein C).

LOXL3_MOUSE
NC score	0.822240 (rank : 11)	θ value	1.01059e-59 (rank : 10)
Query Neighborhood Hits	64	Target Neighborhood Hits	48	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Z175, Q9JJ39	Gene names	Loxl3, Lor2
Domain Architecture
Description	Lysyl oxidase homolog 3 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 3) (Lysyl oxidase-related protein 2).

LOXL3_HUMAN
NC score	0.820612 (rank : 12)	θ value	6.55044e-59 (rank : 12)
Query Neighborhood Hits	64	Target Neighborhood Hits	47	Shared Neighborhood Hits	33
SwissProt Accessions	P58215, Q96RS1	Gene names	LOXL3, LOXL
Domain Architecture
Description	Lysyl oxidase homolog 3 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 3).

LOXL2_MOUSE
NC score	0.819737 (rank : 13)	θ value	1.32293e-51 (rank : 15)
Query Neighborhood Hits	64	Target Neighborhood Hits	44	Shared Neighborhood Hits	32
SwissProt Accessions	P58022, Q8BRE6, Q8BS86, Q8C4K0, Q9JJ39	Gene names	Loxl2
Domain Architecture	No domain graphic available
Description	Lysyl oxidase homolog 2 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 2).

LOXL2_HUMAN
NC score	0.818968 (rank : 14)	θ value	1.08223e-53 (rank : 14)
Query Neighborhood Hits	64	Target Neighborhood Hits	49	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y4K0, Q9BW70, Q9Y5Y8	Gene names	LOXL2
Domain Architecture
Description	Lysyl oxidase homolog 2 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 2) (Lysyl oxidase-related protein 2) (Lysyl oxidase-related protein WS9-14).

DMBT1_HUMAN
NC score	0.795238 (rank : 15)	θ value	0 (rank : 4)
Query Neighborhood Hits	64	Target Neighborhood Hits	152	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DMBT1_MOUSE
NC score	0.715717 (rank : 16)	θ value	1.31915e-176 (rank : 5)
Query Neighborhood Hits	64	Target Neighborhood Hits	134	Shared Neighborhood Hits	38
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

MSRE_MOUSE
NC score	0.663774 (rank : 17)	θ value	7.30988e-26 (rank : 19)
Query Neighborhood Hits	64	Target Neighborhood Hits	307	Shared Neighborhood Hits	31
SwissProt Accessions	P30204, Q923G0, Q9QZ56	Gene names	Msr1, Scvr
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor type A) (SR-A).

CD5_MOUSE
NC score	0.628729 (rank : 18)	θ value	1.16975e-15 (rank : 23)
Query Neighborhood Hits	64	Target Neighborhood Hits	33	Shared Neighborhood Hits	24
SwissProt Accessions	P13379	Gene names	Cd5, Ly-1
Domain Architecture
Description	T-cell surface glycoprotein CD5 precursor (Lymphocyte antigen Ly-1) (Lyt-1).

MSRE_HUMAN
NC score	0.604899 (rank : 19)	θ value	1.24688e-25 (rank : 20)
Query Neighborhood Hits	64	Target Neighborhood Hits	298	Shared Neighborhood Hits	32
SwissProt Accessions	P21757, P21759, Q45F10	Gene names	MSR1, SCARA1
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor class A member 1) (CD204 antigen).

CD5_HUMAN
NC score	0.600161 (rank : 20)	θ value	2.60593e-15 (rank : 24)
Query Neighborhood Hits	64	Target Neighborhood Hits	36	Shared Neighborhood Hits	23
SwissProt Accessions	P06127	Gene names	CD5, LEU1
Domain Architecture
Description	T-cell surface glycoprotein CD5 precursor (Lymphocyte antigen T1/Leu- 1).

MARCO_HUMAN
NC score	0.520111 (rank : 21)	θ value	3.62785e-25 (rank : 21)
Query Neighborhood Hits	64	Target Neighborhood Hits	199	Shared Neighborhood Hits	27
SwissProt Accessions	Q9UEW3, Q9Y5S3	Gene names	MARCO, SCARA2
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2).

NETR_HUMAN
NC score	0.468931 (rank : 22)	θ value	8.49582e-83 (rank : 6)
Query Neighborhood Hits	64	Target Neighborhood Hits	218	Shared Neighborhood Hits	42
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

NETR_MOUSE
NC score	0.453495 (rank : 23)	θ value	1.07722e-69 (rank : 8)
Query Neighborhood Hits	64	Target Neighborhood Hits	216	Shared Neighborhood Hits	42
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

MARCO_MOUSE
NC score	0.416670 (rank : 24)	θ value	1.05554e-24 (rank : 22)
Query Neighborhood Hits	64	Target Neighborhood Hits	242	Shared Neighborhood Hits	30
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

LYOX_HUMAN
NC score	0.278744 (rank : 25)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	64	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P28300, Q5FWF0	Gene names	LOX
Domain Architecture
Description	Protein-lysine 6-oxidase precursor (EC 1.4.3.13) (Lysyl oxidase).

LYOX_MOUSE
NC score	0.276626 (rank : 26)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	64	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	P28301	Gene names	Lox, Rrg
Domain Architecture
Description	Protein-lysine 6-oxidase precursor (EC 1.4.3.13) (Lysyl oxidase) (RAS excision protein).

LOXL1_HUMAN
NC score	0.265209 (rank : 27)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	64	Target Neighborhood Hits	31	Shared Neighborhood Hits	6
SwissProt Accessions	Q08397, Q96BW7	Gene names	LOXL1, LOXL
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (LOL).

LOXL1_MOUSE
NC score	0.264283 (rank : 28)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	64	Target Neighborhood Hits	58	Shared Neighborhood Hits	6
SwissProt Accessions	P97873, Q91ZY4, Q99KX3	Gene names	Loxl1, Lox2, Loxl
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (Lysyl oxidase 2).

CFAI_HUMAN
NC score	0.147363 (rank : 29)	θ value	6.43352e-06 (rank : 25)
Query Neighborhood Hits	64	Target Neighborhood Hits	289	Shared Neighborhood Hits	41
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CFAI_MOUSE
NC score	0.144640 (rank : 30)	θ value	9.29e-05 (rank : 26)
Query Neighborhood Hits	64	Target Neighborhood Hits	290	Shared Neighborhood Hits	40
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CUZD1_MOUSE
NC score	0.139080 (rank : 31)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	64	Target Neighborhood Hits	91	Shared Neighborhood Hits	8
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

ENTK_MOUSE
NC score	0.137955 (rank : 32)	θ value	0.0113563 (rank : 31)
Query Neighborhood Hits	64	Target Neighborhood Hits	338	Shared Neighborhood Hits	41
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

CUZD1_HUMAN
NC score	0.134722 (rank : 33)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	64	Target Neighborhood Hits	89	Shared Neighborhood Hits	8
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

ENTK_HUMAN
NC score	0.125128 (rank : 34)	θ value	0.00390308 (rank : 28)
Query Neighborhood Hits	64	Target Neighborhood Hits	310	Shared Neighborhood Hits	42
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

TMPS3_HUMAN
NC score	0.112746 (rank : 35)	θ value	0.00509761 (rank : 29)
Query Neighborhood Hits	64	Target Neighborhood Hits	245	Shared Neighborhood Hits	41
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

TMPS3_MOUSE
NC score	0.108751 (rank : 36)	θ value	0.0193708 (rank : 32)
Query Neighborhood Hits	64	Target Neighborhood Hits	239	Shared Neighborhood Hits	41
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

TMPSD_MOUSE
NC score	0.105155 (rank : 37)	θ value	0.00665767 (rank : 30)
Query Neighborhood Hits	64	Target Neighborhood Hits	334	Shared Neighborhood Hits	38
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

CORIN_MOUSE
NC score	0.089392 (rank : 38)	θ value	0.000461057 (rank : 27)
Query Neighborhood Hits	64	Target Neighborhood Hits	451	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

ST14_MOUSE
NC score	0.089322 (rank : 39)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	64	Target Neighborhood Hits	419	Shared Neighborhood Hits	27
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

ST14_HUMAN
NC score	0.086878 (rank : 40)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	64	Target Neighborhood Hits	409	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

TMPS4_MOUSE
NC score	0.086315 (rank : 41)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	64	Target Neighborhood Hits	210	Shared Neighborhood Hits	35
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

TMPS2_HUMAN
NC score	0.086207 (rank : 42)	θ value	0.0252991 (rank : 33)
Query Neighborhood Hits	64	Target Neighborhood Hits	252	Shared Neighborhood Hits	33
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS5_MOUSE
NC score	0.085760 (rank : 43)	θ value	0.0736092 (rank : 35)
Query Neighborhood Hits	64	Target Neighborhood Hits	185	Shared Neighborhood Hits	28
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPSD_HUMAN
NC score	0.084187 (rank : 44)	θ value	0.365318 (rank : 39)
Query Neighborhood Hits	64	Target Neighborhood Hits	333	Shared Neighborhood Hits	30
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

CS1B_MOUSE
NC score	0.080657 (rank : 45)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	64	Target Neighborhood Hits	361	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

C1S_HUMAN
NC score	0.079708 (rank : 46)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	64	Target Neighborhood Hits	359	Shared Neighborhood Hits	28
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CS1A_MOUSE
NC score	0.079679 (rank : 47)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	64	Target Neighborhood Hits	360	Shared Neighborhood Hits	28
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

MASP1_HUMAN
NC score	0.079669 (rank : 48)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	64	Target Neighborhood Hits	369	Shared Neighborhood Hits	30
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

TMPS5_HUMAN
NC score	0.079272 (rank : 49)	θ value	0.279714 (rank : 37)
Query Neighborhood Hits	64	Target Neighborhood Hits	181	Shared Neighborhood Hits	25
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

MASP2_HUMAN
NC score	0.078959 (rank : 50)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	64	Target Neighborhood Hits	364	Shared Neighborhood Hits	29
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP1_MOUSE
NC score	0.078923 (rank : 51)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	64	Target Neighborhood Hits	364	Shared Neighborhood Hits	29
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

TMPS7_HUMAN
NC score	0.078382 (rank : 52)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	64	Target Neighborhood Hits	275	Shared Neighborhood Hits	25
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

C1R_HUMAN
NC score	0.077684 (rank : 53)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	64	Target Neighborhood Hits	364	Shared Neighborhood Hits	29
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

ZP2_HUMAN
NC score	0.077594 (rank : 54)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	64	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q05996	Gene names	ZP2, ZPA
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

C1RB_MOUSE
NC score	0.077422 (rank : 55)	θ value	8.99809 (rank : 59)
Query Neighborhood Hits	64	Target Neighborhood Hits	380	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1RA_MOUSE
NC score	0.076992 (rank : 56)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	64	Target Neighborhood Hits	379	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

TMPS2_MOUSE
NC score	0.076961 (rank : 57)	θ value	0.0563607 (rank : 34)
Query Neighborhood Hits	64	Target Neighborhood Hits	243	Shared Neighborhood Hits	26
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS7_MOUSE
NC score	0.075471 (rank : 58)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	64	Target Neighborhood Hits	275	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

CORIN_HUMAN
NC score	0.075457 (rank : 59)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	64	Target Neighborhood Hits	453	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

MASP2_MOUSE
NC score	0.075389 (rank : 60)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	64	Target Neighborhood Hits	382	Shared Neighborhood Hits	29
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

TMPS4_HUMAN
NC score	0.074160 (rank : 61)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	64	Target Neighborhood Hits	203	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

PCOC2_MOUSE
NC score	0.073592 (rank : 62)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	64	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_HUMAN
NC score	0.072720 (rank : 63)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	64	Target Neighborhood Hits	73	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

TLL1_MOUSE
NC score	0.071992 (rank : 64)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	64	Target Neighborhood Hits	237	Shared Neighborhood Hits	14
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL1_HUMAN
NC score	0.071028 (rank : 65)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	64	Target Neighborhood Hits	236	Shared Neighborhood Hits	14
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

LRP12_HUMAN
NC score	0.070667 (rank : 66)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	64	Target Neighborhood Hits	205	Shared Neighborhood Hits	19
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
NC score	0.070602 (rank : 67)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	64	Target Neighborhood Hits	180	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

ZP2_MOUSE
NC score	0.070380 (rank : 68)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	64	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	P20239	Gene names	Zp2, Zp-2, Zpa
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

TLL2_MOUSE
NC score	0.069581 (rank : 69)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	64	Target Neighborhood Hits	240	Shared Neighborhood Hits	14
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_HUMAN
NC score	0.069020 (rank : 70)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	64	Target Neighborhood Hits	241	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TECTB_MOUSE
NC score	0.068276 (rank : 71)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	64	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	O08524	Gene names	Tectb
Domain Architecture
Description	Beta-tectorin precursor.

TECTB_HUMAN
NC score	0.068218 (rank : 72)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	64	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q96PL2	Gene names	TECTB
Domain Architecture
Description	Beta-tectorin precursor.

ZP4_HUMAN
NC score	0.068179 (rank : 73)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	64	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q12836	Gene names	ZP4, ZPB
Domain Architecture
Description	Zona pellucida sperm-binding protein 4 precursor (Zona pellucida sperm-binding protein B).

MFRP_MOUSE
NC score	0.068170 (rank : 74)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	64	Target Neighborhood Hits	166	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

HEPS_HUMAN
NC score	0.067708 (rank : 75)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	P05981	Gene names	HPN, TMPRSS1
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) (Transmembrane protease, serine 1) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

ACRO_MOUSE
NC score	0.067533 (rank : 76)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	64	Target Neighborhood Hits	185	Shared Neighborhood Hits	20
SwissProt Accessions	P23578	Gene names	Acr
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

MFRP_HUMAN
NC score	0.067293 (rank : 77)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	64	Target Neighborhood Hits	165	Shared Neighborhood Hits	15
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

PCOC1_MOUSE
NC score	0.067242 (rank : 78)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	64	Target Neighborhood Hits	100	Shared Neighborhood Hits	7
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

HEPS_MOUSE
NC score	0.067141 (rank : 79)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	22
SwissProt Accessions	O35453, Q9CW97	Gene names	Hpn
Domain Architecture
Description	Serine protease hepsin (EC 3.4.21.-) [Contains: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain].

TSG6_HUMAN
NC score	0.067128 (rank : 80)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	64	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
NC score	0.067053 (rank : 81)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	64	Target Neighborhood Hits	91	Shared Neighborhood Hits	7
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

ACRO_HUMAN
NC score	0.066915 (rank : 82)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	64	Target Neighborhood Hits	291	Shared Neighborhood Hits	20
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

TGBR3_HUMAN
NC score	0.066890 (rank : 83)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	64	Target Neighborhood Hits	44	Shared Neighborhood Hits	3
SwissProt Accessions	Q03167, Q5T2T4, Q5U731, Q9UGI2	Gene names	TGFBR3
Domain Architecture
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

TM11E_HUMAN
NC score	0.066701 (rank : 84)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	64	Target Neighborhood Hits	181	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UL52, Q6UW31	Gene names	TMPRSS11E, DESC1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

BMP1_MOUSE
NC score	0.066618 (rank : 85)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	64	Target Neighborhood Hits	236	Shared Neighborhood Hits	13
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

NETO2_MOUSE
NC score	0.066578 (rank : 86)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	64	Target Neighborhood Hits	113	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

TEST_HUMAN
NC score	0.066502 (rank : 87)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	64	Target Neighborhood Hits	172	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y6M0, Q9NS34, Q9P2V6	Gene names	PRSS21, ESP1, TEST1
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Eosinophil serine protease 1) (ESP- 1).

BMP1_HUMAN
NC score	0.066413 (rank : 88)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	64	Target Neighborhood Hits	233	Shared Neighborhood Hits	13
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

NETO2_HUMAN
NC score	0.066348 (rank : 89)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	64	Target Neighborhood Hits	109	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

TMPS6_HUMAN
NC score	0.066150 (rank : 90)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	64	Target Neighborhood Hits	338	Shared Neighborhood Hits	26
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TSP50_HUMAN
NC score	0.066103 (rank : 91)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UI38	Gene names	TSP50
Domain Architecture
Description	Testis-specific protease-like protein 50 precursor.

TM11D_MOUSE
NC score	0.065907 (rank : 92)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	64	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	Q8VHK8, Q7TNX3, Q8VDV1	Gene names	Tmprss11d, Mat
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) (AT) (Adrenal secretory serine protease) (AsP) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

PCOC1_HUMAN
NC score	0.065830 (rank : 93)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	64	Target Neighborhood Hits	146	Shared Neighborhood Hits	6
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

DESC4_MOUSE
NC score	0.065661 (rank : 94)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BZ10, Q8BZ04	Gene names	Desc4
Domain Architecture	No domain graphic available
Description	Serine protease DESC4 precursor (EC 3.4.21.-) [Contains: Serine protease DESC4 non-catalytic chain; Serine protease DESC4 catalytic chain].

FA11_HUMAN
NC score	0.065603 (rank : 95)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	P03951, Q9Y495	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

TPA_MOUSE
NC score	0.065593 (rank : 96)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	64	Target Neighborhood Hits	335	Shared Neighborhood Hits	26
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TM11D_HUMAN
NC score	0.065509 (rank : 97)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	O60235	Gene names	TMPRSS11D, HAT
Domain Architecture
Description	Transmembrane protease, serine 11D precursor (EC 3.4.21.-) (Airway trypsin-like protease) [Contains: Transmembrane protease, serine 11D non-catalytic chain; Transmembrane protease, serine 11D catalytic chain].

TM11E_MOUSE
NC score	0.065420 (rank : 98)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q5S248, Q8BM10	Gene names	Tmprss11e, Desc1
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 11E precursor (EC 3.4.21.-) (Serine protease DESC1) [Contains: Transmembrane protease, serine 11E non- catalytic chain; Transmembrane protease, serine 11E catalytic chain].

TMPS6_MOUSE
NC score	0.065298 (rank : 99)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	64	Target Neighborhood Hits	341	Shared Neighborhood Hits	24
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

NETO1_HUMAN
NC score	0.065265 (rank : 100)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	64	Target Neighborhood Hits	110	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

TMSP8_MOUSE
NC score	0.065207 (rank : 101)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QYZ9, Q91XC4	Gene names	Tmprss8, Disp
Domain Architecture
Description	Transmembrane serine protease 8 precursor (EC 3.4.21.-) (Distal intestinal serine protease).

TGBR3_MOUSE
NC score	0.065162 (rank : 102)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	64	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	O88393, Q6NS72	Gene names	Tgfbr3
Domain Architecture	No domain graphic available
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

KLKB1_MOUSE
NC score	0.065009 (rank : 103)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P26262	Gene names	Klkb1, Klk3, Pk
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

TRYG1_MOUSE
NC score	0.064684 (rank : 104)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	64	Target Neighborhood Hits	181	Shared Neighborhood Hits	21
SwissProt Accessions	Q9QUL7	Gene names	Tpsg1, Tmt
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

FA11_MOUSE
NC score	0.064588 (rank : 105)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	64	Target Neighborhood Hits	180	Shared Neighborhood Hits	20
SwissProt Accessions	Q91Y47	Gene names	F11
Domain Architecture
Description	Coagulation factor XI precursor (EC 3.4.21.27) (Plasma thromboplastin antecedent) (PTA) (FXI) [Contains: Coagulation factor XIa heavy chain; Coagulation factor XIa light chain].

NETO1_MOUSE
NC score	0.064491 (rank : 106)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	64	Target Neighborhood Hits	109	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

TMPS9_HUMAN
NC score	0.064181 (rank : 107)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	64	Target Neighborhood Hits	276	Shared Neighborhood Hits	22
SwissProt Accessions	Q7Z410, Q6ZND6, Q7Z411	Gene names	TMPRSS9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserase-I) (Polyserine protease 1) [Contains: Serase-1; Serase-2; Serase-3].

TPA_HUMAN
NC score	0.064117 (rank : 108)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	64	Target Neighborhood Hits	324	Shared Neighborhood Hits	23
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

UROK_HUMAN
NC score	0.064094 (rank : 109)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	64	Target Neighborhood Hits	272	Shared Neighborhood Hits	22
SwissProt Accessions	P00749, Q15844, Q16618, Q969W6	Gene names	PLAU
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

TRYG1_HUMAN
NC score	0.063985 (rank : 110)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	64	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NRR2, Q96RZ8, Q9C015, Q9NRQ8, Q9UBB2	Gene names	TPSG1, TMT
Domain Architecture
Description	Tryptase gamma precursor (EC 3.4.21.-) (Transmembrane tryptase) [Contains: Tryptase gamma light chain; Tryptase gamma heavy chain].

KLKB1_HUMAN
NC score	0.063910 (rank : 111)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	64	Target Neighborhood Hits	183	Shared Neighborhood Hits	20
SwissProt Accessions	P03952	Gene names	KLKB1, KLK3
Domain Architecture
Description	Plasma kallikrein precursor (EC 3.4.21.34) (Plasma prekallikrein) (Kininogenin) (Fletcher factor) [Contains: Plasma kallikrein heavy chain; Plasma kallikrein light chain].

TMPS9_MOUSE
NC score	0.063849 (rank : 112)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	64	Target Neighborhood Hits	296	Shared Neighborhood Hits	22
SwissProt Accessions	P69525	Gene names	Tmprss9
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 9 (EC 3.4.21.-) (Polyserase-1) (Polyserine protease 1) (Polyserase-I) [Contains: Serase-1; Serase-2; Serase-3].

TEST_MOUSE
NC score	0.063441 (rank : 113)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	64	Target Neighborhood Hits	174	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JHJ7, Q9DA14	Gene names	Prss21
Domain Architecture
Description	Testisin precursor (EC 3.4.21.-) (Tryptase 4).

ZP3_MOUSE
NC score	0.063380 (rank : 114)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	64	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P10761	Gene names	Zp3, Zp-3, Zpc
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 precursor (Zona pellucida glycoprotein ZP3) (Sperm receptor) (Zona pellucida protein C).

PRS27_MOUSE
NC score	0.063270 (rank : 115)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BJR6	Gene names	Prss27, Mpn
Domain Architecture	No domain graphic available
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin).

BSSP4_HUMAN
NC score	0.062918 (rank : 116)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q9GZN4, O43342, Q6UXE0	Gene names	PRSS22, BSSP4, PRSS26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

CLCR_HUMAN
NC score	0.062887 (rank : 117)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	Q99895, O00765, Q9NUH5	Gene names	CTRC, CLCR
Domain Architecture
Description	Caldecrin precursor (EC 3.4.21.2) (Chymotrypsin C).

PRS27_HUMAN
NC score	0.062883 (rank : 118)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BQR3	Gene names	PRSS27, MPN
Domain Architecture
Description	Protease serine 27 precursor (EC 3.4.21.-) (Marapsin) (Pancreasin) (Channel-activating protease 2) (CAPH2).

BSSP4_MOUSE
NC score	0.062716 (rank : 119)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	64	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ER10	Gene names	Prss22, Bssp4, Prss26
Domain Architecture
Description	Brain-specific serine protease 4 precursor (EC 3.4.21.-) (BSSP-4) (Serine protease 22) (Tryptase epsilon).

PRSS8_MOUSE
NC score	0.062170 (rank : 120)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	Q9ESD1	Gene names	Prss8, Cap1
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) (Channel-activating protease 1) [Contains: Prostasin light chain; Prostasin heavy chain].

POLS2_HUMAN
NC score	0.062105 (rank : 121)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	64	Target Neighborhood Hits	192	Shared Neighborhood Hits	20
SwissProt Accessions	Q5K4E3, Q8NBY4	Gene names	PRSS36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

CTRL_HUMAN
NC score	0.062026 (rank : 122)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	64	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	P40313	Gene names	CTRL, CTRL1
Domain Architecture
Description	Chymotrypsin-like protease CTRL-1 precursor (EC 3.4.21.-).

UROK_MOUSE
NC score	0.061944 (rank : 123)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	64	Target Neighborhood Hits	273	Shared Neighborhood Hits	22
SwissProt Accessions	P06869	Gene names	Plau
Domain Architecture
Description	Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA) (U-plasminogen activator) [Contains: Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A; Urokinase-type plasminogen activator chain B].

MCPT6_MOUSE
NC score	0.061842 (rank : 124)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	P21845, Q61962	Gene names	Mcpt6
Domain Architecture
Description	Mast cell protease 6 precursor (EC 3.4.21.59) (MMCP-6) (Tryptase).

CTRB1_HUMAN
NC score	0.061509 (rank : 125)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	P17538	Gene names	CTRB1, CTRB
Domain Architecture
Description	Chymotrypsinogen B precursor (EC 3.4.21.1) [Contains: Chymotrypsin B chain A; Chymotrypsin B chain B; Chymotrypsin B chain C].

HGFA_HUMAN
NC score	0.061209 (rank : 126)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	64	Target Neighborhood Hits	436	Shared Neighborhood Hits	28
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

PRSS8_HUMAN
NC score	0.061202 (rank : 127)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	Q16651, Q9UCA3	Gene names	PRSS8
Domain Architecture
Description	Prostasin precursor (EC 3.4.21.-) [Contains: Prostasin light chain; Prostasin heavy chain].

TRYB1_HUMAN
NC score	0.060992 (rank : 128)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	Q15661, Q15663, Q9H2Y4	Gene names	TPSAB1, TPSB1
Domain Architecture
Description	Tryptase beta-1 precursor (EC 3.4.21.59) (Tryptase-1) (Tryptase I).

TRYB2_HUMAN
NC score	0.060992 (rank : 129)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	P20231, O95827, Q15664, Q9UQI6, Q9UQI7	Gene names	TPSB2, TPS2
Domain Architecture
Description	Tryptase beta-2 precursor (EC 3.4.21.59) (Tryptase-2) (Tryptase II).

TRYA1_HUMAN
NC score	0.060935 (rank : 130)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P15157, Q9H2Y5, Q9UQI1	Gene names	TPSAB1, TPS1
Domain Architecture
Description	Tryptase alpha-1 precursor (EC 3.4.21.59) (Tryptase-1).

ELA2A_HUMAN
NC score	0.060818 (rank : 131)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	64	Target Neighborhood Hits	180	Shared Neighborhood Hits	20
SwissProt Accessions	P08217, Q14243	Gene names	ELA2A
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71).

ELA1_HUMAN
NC score	0.060785 (rank : 132)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UNI1, Q5MLF0, Q6DJT0, Q6ISM6	Gene names	ELA1
Domain Architecture
Description	Elastase-1 precursor (EC 3.4.21.36).

GP2_MOUSE
NC score	0.060772 (rank : 133)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	64	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D733	Gene names	Gp2
Domain Architecture	No domain graphic available
Description	Pancreatic secretory granule membrane major glycoprotein GP2 precursor (Pancreatic zymogen granule membrane protein GP-2).

ELA2A_MOUSE
NC score	0.060724 (rank : 134)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	P05208	Gene names	Ela2a, Ela-2, Ela2
Domain Architecture
Description	Elastase-2A precursor (EC 3.4.21.71) (Elastase-2).

POLS2_MOUSE
NC score	0.060713 (rank : 135)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	64	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	Q5K2P8	Gene names	Prss36
Domain Architecture	No domain graphic available
Description	Polyserase-2 precursor (EC 3.4.21.-) (Polyserine protease 2) (Protease serine 36).

ELA2B_HUMAN
NC score	0.060449 (rank : 136)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	P08218	Gene names	ELA2B
Domain Architecture
Description	Elastase-2B precursor (EC 3.4.21.71).

ELA3A_HUMAN
NC score	0.060311 (rank : 137)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	64	Target Neighborhood Hits	173	Shared Neighborhood Hits	20
SwissProt Accessions	P09093, Q9BRW4	Gene names	ELA3A, ELA3
Domain Architecture
Description	Elastase-3A precursor (EC 3.4.21.70) (Elastase IIIA) (Protease E).

TRYB1_MOUSE
NC score	0.059994 (rank : 138)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	Q02844	Gene names	Tpsab1, Mcpt7
Domain Architecture
Description	Tryptase precursor (EC 3.4.21.59) (Mast cell protease 7) (MMCP-7) (Tryptase alpha/beta-1).

FA12_HUMAN
NC score	0.059925 (rank : 139)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	64	Target Neighborhood Hits	425	Shared Neighborhood Hits	27
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

PROC_HUMAN
NC score	0.059887 (rank : 140)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	64	Target Neighborhood Hits	406	Shared Neighborhood Hits	27
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

ELA3B_HUMAN
NC score	0.059710 (rank : 141)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	P08861, P11423, Q5VU28, Q5VU29, Q5VU30	Gene names	ELA3B
Domain Architecture
Description	Elastase-3B precursor (EC 3.4.21.70) (Elastase IIIB) (Protease E).

HGFA_MOUSE
NC score	0.059587 (rank : 142)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	64	Target Neighborhood Hits	419	Shared Neighborhood Hits	28
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

ZP3_HUMAN
NC score	0.059487 (rank : 143)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	64	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	P21754, Q06633	Gene names	ZP3, ZP3A, ZPC
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 precursor (Zona pellucida glycoprotein ZP3) (Zona pellucida protein C) (Sperm receptor) (ZP3A/ZP3B).

FA10_HUMAN
NC score	0.059225 (rank : 144)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	64	Target Neighborhood Hits	431	Shared Neighborhood Hits	27
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FA7_MOUSE
NC score	0.059213 (rank : 145)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	64	Target Neighborhood Hits	374	Shared Neighborhood Hits	25
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

TRYD_HUMAN
NC score	0.059188 (rank : 146)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BZJ3, O95824, Q8TDI6, Q96L36, Q96RZ5, Q9H2Y6, Q9UQI8	Gene names	TPSD1
Domain Architecture
Description	Tryptase delta precursor (EC 3.4.21.59) (Delta tryptase) (Mast cell mMCP-7-like) (Tryptase-3) (HmMCP-3-like tryptase III).

CSMD2_HUMAN
NC score	0.058759 (rank : 147)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	64	Target Neighborhood Hits	188	Shared Neighborhood Hits	11
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

FA10_MOUSE
NC score	0.058687 (rank : 148)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	64	Target Neighborhood Hits	435	Shared Neighborhood Hits	27
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

CFAD_MOUSE
NC score	0.058560 (rank : 149)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P03953, Q61280	Gene names	Cfd, Adn, Df
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin) (28 kDa adipocyte protein).

HABP2_HUMAN
NC score	0.058498 (rank : 150)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	64	Target Neighborhood Hits	431	Shared Neighborhood Hits	27
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

PLMN_MOUSE
NC score	0.058339 (rank : 151)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	64	Target Neighborhood Hits	208	Shared Neighborhood Hits	20
SwissProt Accessions	P20918, Q8CIS2, Q91WJ5	Gene names	Plg
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

PROC_MOUSE
NC score	0.058325 (rank : 152)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	64	Target Neighborhood Hits	426	Shared Neighborhood Hits	28
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

FA7_HUMAN
NC score	0.058318 (rank : 153)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	64	Target Neighborhood Hits	404	Shared Neighborhood Hits	27
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

PLMN_HUMAN
NC score	0.058167 (rank : 154)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	64	Target Neighborhood Hits	204	Shared Neighborhood Hits	20
SwissProt Accessions	P00747, Q15146, Q6PA00	Gene names	PLG
Domain Architecture
Description	Plasminogen precursor (EC 3.4.21.7) [Contains: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B].

HABP2_MOUSE
NC score	0.058138 (rank : 155)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	64	Target Neighborhood Hits	445	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

KLK6_HUMAN
NC score	0.058005 (rank : 156)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	Q92876	Gene names	KLK6, PRSS18, PRSS9
Domain Architecture
Description	Kallikrein-6 precursor (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59).

KLK10_HUMAN
NC score	0.057986 (rank : 157)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	21
SwissProt Accessions	O43240, Q99920, Q9GZW9	Gene names	KLK10, NES1, PRRSL1
Domain Architecture
Description	Kallikrein-10 precursor (EC 3.4.21.-) (Protease serine-like 1) (Normal epithelial cell-specific 1).

THRB_HUMAN
NC score	0.057885 (rank : 158)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	64	Target Neighborhood Hits	196	Shared Neighborhood Hits	20
SwissProt Accessions	P00734	Gene names	F2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

CFAD_HUMAN
NC score	0.057672 (rank : 159)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	P00746	Gene names	CFD, DF
Domain Architecture
Description	Complement factor D precursor (EC 3.4.21.46) (C3 convertase activator) (Properdin factor D) (Adipsin).

TRY2_MOUSE
NC score	0.057588 (rank : 160)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	64	Target Neighborhood Hits	174	Shared Neighborhood Hits	20
SwissProt Accessions	P07146	Gene names	Prss2, Try2
Domain Architecture
Description	Anionic trypsin-2 precursor (EC 3.4.21.4) (Anionic trypsin II) (Pretrypsinogen II).

KLK13_HUMAN
NC score	0.057493 (rank : 161)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	64	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKR3, Q9Y433	Gene names	KLK13, KLKL4
Domain Architecture
Description	Kallikrein-13 precursor (EC 3.4.21.-) (Kallikrein-like protein 4) (KLK-L4).

TRY3_HUMAN
NC score	0.057421 (rank : 162)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	P35030, P15951, Q15665, Q9UQV3	Gene names	PRSS3, PRSS4, TRY3, TRY4
Domain Architecture
Description	Trypsin-3 precursor (EC 3.4.21.4) (Trypsin III) (Brain trypsinogen) (Mesotrypsinogen) (Trypsin IV).

APOA_HUMAN
NC score	0.057288 (rank : 163)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	64	Target Neighborhood Hits	221	Shared Neighborhood Hits	20
SwissProt Accessions	P08519	Gene names	LPA
Domain Architecture
Description	Apolipoprotein(a) precursor (EC 3.4.21.-) (Apo(a)) (Lp(a)).

HPT_HUMAN
NC score	0.057037 (rank : 164)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	64	Target Neighborhood Hits	184	Shared Neighborhood Hits	21
SwissProt Accessions	P00738, P00737, Q2PP15, Q3B7J0, Q6LBY9	Gene names	HP
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

KREM1_MOUSE
NC score	0.057032 (rank : 165)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	64	Target Neighborhood Hits	92	Shared Neighborhood Hits	10
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

TRY1_HUMAN
NC score	0.057019 (rank : 166)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	P07477, Q92955, Q9HAN4, Q9HAN5, Q9HAN6, Q9HAN7	Gene names	PRSS1, TRP1, TRY1, TRYP1
Domain Architecture
Description	Trypsin-1 precursor (EC 3.4.21.4) (Trypsin I) (Cationic trypsinogen).

HPTR_HUMAN
NC score	0.056971 (rank : 167)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	64	Target Neighborhood Hits	166	Shared Neighborhood Hits	20
SwissProt Accessions	P00739, Q7LE20, Q92658, Q92659, Q9ULB0	Gene names	HPR
Domain Architecture
Description	Haptoglobin-related protein precursor.

HPT_MOUSE
NC score	0.056960 (rank : 168)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	64	Target Neighborhood Hits	178	Shared Neighborhood Hits	20
SwissProt Accessions	Q61646	Gene names	Hp
Domain Architecture
Description	Haptoglobin precursor [Contains: Haptoglobin alpha chain; Haptoglobin beta chain].

THRB_MOUSE
NC score	0.056941 (rank : 169)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	64	Target Neighborhood Hits	195	Shared Neighborhood Hits	20
SwissProt Accessions	P19221	Gene names	F2, Cf2
Domain Architecture
Description	Prothrombin precursor (EC 3.4.21.5) (Coagulation factor II) [Contains: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain].

TRY2_HUMAN
NC score	0.056834 (rank : 170)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	P07478	Gene names	PRSS2, TRY2, TRYP2
Domain Architecture
Description	Trypsin-2 precursor (EC 3.4.21.4) (Trypsin II) (Anionic trypsinogen).

NRPN_MOUSE
NC score	0.056725 (rank : 171)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	64	Target Neighborhood Hits	186	Shared Neighborhood Hits	20
SwissProt Accessions	Q61955	Gene names	Klk8, Nrpn, Prss19
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8).

GRAK_MOUSE
NC score	0.056051 (rank : 172)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	64	Target Neighborhood Hits	174	Shared Neighborhood Hits	20
SwissProt Accessions	O35205	Gene names	Gzmk
Domain Architecture
Description	Granzyme K precursor (EC 3.4.21.-).

NRPN_HUMAN
NC score	0.055999 (rank : 173)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	64	Target Neighborhood Hits	182	Shared Neighborhood Hits	20
SwissProt Accessions	O60259, Q9HCB3, Q9UIL9, Q9UQ47	Gene names	KLK8, NRPN, PRSS19, TADG14
Domain Architecture
Description	Neuropsin precursor (EC 3.4.21.-) (NP) (Kallikrein-8) (Ovasin) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein).

KLK7_MOUSE
NC score	0.055350 (rank : 174)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	Q91VE3, Q9R048	Gene names	Klk7, Prss6, Scce
Domain Architecture	No domain graphic available
Description	Kallikrein-7 precursor (EC 3.4.21.-) (Stratum corneum chymotryptic enzyme) (Thymopsin).

FA9_HUMAN
NC score	0.055123 (rank : 175)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	64	Target Neighborhood Hits	421	Shared Neighborhood Hits	27
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

KLK15_HUMAN
NC score	0.054954 (rank : 176)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	64	Target Neighborhood Hits	180	Shared Neighborhood Hits	20
SwissProt Accessions	Q9H2R5, Q15358, Q9H2R3, Q9H2R4, Q9H2R6, Q9HBG9	Gene names	KLK15
Domain Architecture
Description	Kallikrein-15 precursor (EC 3.4.21.-) (ACO protease).

GRAM_HUMAN
NC score	0.054905 (rank : 177)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	64	Target Neighborhood Hits	174	Shared Neighborhood Hits	20
SwissProt Accessions	P51124	Gene names	GZMM, MET1
Domain Architecture
Description	Granzyme M precursor (EC 3.4.21.-) (Met-ase) (Natural killer cell granular protease) (HU-Met-1) (Met-1 serine protease).

ZP1_MOUSE
NC score	0.054631 (rank : 178)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	64	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q62005, Q62016	Gene names	Zp1
Domain Architecture
Description	Zona pellucida sperm-binding protein 1 precursor (Zona pellucida glycoprotein 1) (Zp-1).

KLK12_HUMAN
NC score	0.054457 (rank : 179)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	64	Target Neighborhood Hits	197	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKR0, Q9UKR1	Gene names	KLK12, KLKL5
Domain Architecture
Description	Kallikrein-12 precursor (EC 3.4.21.-) (Kallikrein-like protein 5) (KLK-L5).

HGFL_MOUSE
NC score	0.054424 (rank : 180)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	64	Target Neighborhood Hits	188	Shared Neighborhood Hits	20
SwissProt Accessions	P26928	Gene names	Mst1, Hgfl
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

HGFL_HUMAN
NC score	0.054416 (rank : 181)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	64	Target Neighborhood Hits	190	Shared Neighborhood Hits	20
SwissProt Accessions	P26927, Q13350, Q14870	Gene names	MST1, HGFL
Domain Architecture
Description	Hepatocyte growth factor-like protein precursor (Macrophage stimulatory protein) (MSP) (Macrophage-stimulating protein) [Contains: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain].

KLK7_HUMAN
NC score	0.054170 (rank : 182)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	P49862, Q8N5N9, Q8NFV7	Gene names	KLK7, PRSS6, SCCE
Domain Architecture
Description	Kallikrein-7 precursor (EC 3.4.21.-) (hK7) (Stratum corneum chymotryptic enzyme) (hSCCE).

KLK14_HUMAN
NC score	0.054162 (rank : 183)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	64	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P0G3	Gene names	KLK14, KLKL6
Domain Architecture
Description	Kallikrein-14 precursor (EC 3.4.21.-) (Kallikrein-like protein 6) (KLK-L6).

ELNE_MOUSE
NC score	0.054132 (rank : 184)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	64	Target Neighborhood Hits	167	Shared Neighborhood Hits	20
SwissProt Accessions	Q3UP87, Q61515	Gene names	Ela2
Domain Architecture	No domain graphic available
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase).

K1KB1_MOUSE
NC score	0.054124 (rank : 185)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	64	Target Neighborhood Hits	180	Shared Neighborhood Hits	20
SwissProt Accessions	P00755	Gene names	Klk1b1, Klk-1, Klk1
Domain Architecture
Description	Kallikrein 1-related peptidase b1 precursor (EC 3.4.21.35) (Glandular kallikrein K1) (Tissue kallikrein-1) (mGK-1).

KREM1_HUMAN
NC score	0.054034 (rank : 186)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	64	Target Neighborhood Hits	90	Shared Neighborhood Hits	10
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

CUBN_HUMAN
NC score	0.054031 (rank : 187)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	64	Target Neighborhood Hits	482	Shared Neighborhood Hits	18
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

KLK9_HUMAN
NC score	0.053975 (rank : 188)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKQ9	Gene names	KLK9
Domain Architecture
Description	Kallikrein-9 precursor (EC 3.4.21.-) (Kallikrein-like protein 3) (KLK- L3).

K1B11_MOUSE
NC score	0.053971 (rank : 189)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	64	Target Neighborhood Hits	180	Shared Neighborhood Hits	20
SwissProt Accessions	P15946	Gene names	Klk1b11, Klk-11, Klk11
Domain Architecture
Description	Kallikrein 1-related peptidase b11 precursor (EC 3.4.21.35) (Tissue kallikrein-11) (Glandular kallikrein K11) (mGK-11).

KLK11_MOUSE
NC score	0.053772 (rank : 190)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	64	Target Neighborhood Hits	174	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QYN3, Q9QYN4	Gene names	Klk11, Prss20
Domain Architecture	No domain graphic available
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin).

KLK11_HUMAN
NC score	0.053767 (rank : 191)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	64	Target Neighborhood Hits	174	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UBX7, O75837, Q9NS65	Gene names	KLK11, PRSS20, TLSP
Domain Architecture
Description	Kallikrein-11 precursor (EC 3.4.21.-) (Hippostasin) (Trypsin-like protease).

HGF_HUMAN
NC score	0.053566 (rank : 192)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	64	Target Neighborhood Hits	191	Shared Neighborhood Hits	20
SwissProt Accessions	P14210, Q02935, Q13494, Q14519, Q8TCE2, Q9BYL9, Q9BYM0, Q9UDU6	Gene names	HGF, HPTA
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

CATG_MOUSE
NC score	0.053493 (rank : 193)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	64	Target Neighborhood Hits	174	Shared Neighborhood Hits	20
SwissProt Accessions	P28293	Gene names	Ctsg
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (Vimentin-specific protease) (VSP).

MCPT1_MOUSE
NC score	0.053437 (rank : 194)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P11034	Gene names	Mcpt1
Domain Architecture
Description	Mast cell protease 1 precursor (EC 3.4.21.-) (MMCP-1).

HGF_MOUSE
NC score	0.053120 (rank : 195)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	64	Target Neighborhood Hits	192	Shared Neighborhood Hits	20
SwissProt Accessions	Q08048, Q61662, Q64007, Q6LBE6	Gene names	Hgf
Domain Architecture
Description	Hepatocyte growth factor precursor (Scatter factor) (SF) (Hepatopoeitin A) [Contains: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain].

LRP3_HUMAN
NC score	0.053098 (rank : 196)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	64	Target Neighborhood Hits	280	Shared Neighborhood Hits	21
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

CUBN_MOUSE
NC score	0.053094 (rank : 197)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	64	Target Neighborhood Hits	477	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

KLK5_HUMAN
NC score	0.053047 (rank : 198)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	64	Target Neighborhood Hits	182	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y337, Q9HBG8	Gene names	KLK5, SCTE
Domain Architecture
Description	Kallikrein-5 precursor (EC 3.4.21.-) (Stratum corneum tryptic enzyme) (Kallikrein-like protein 2) (KLK-L2).

K1KB9_MOUSE
NC score	0.052907 (rank : 199)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	P15949	Gene names	Klk1b9, Egfbp3, Klk-9, Klk9
Domain Architecture
Description	Kallikrein 1-related peptidase b9 precursor (EC 3.4.21.35) (Tissue kallikrein-9) (Glandular kallikrein K9) (mGK-9) (Epidermal growth factor-binding protein type C) (EGF-BP C).

CATG_HUMAN
NC score	0.052855 (rank : 200)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	64	Target Neighborhood Hits	174	Shared Neighborhood Hits	20
SwissProt Accessions	P08311	Gene names	CTSG
Domain Architecture
Description	Cathepsin G precursor (EC 3.4.21.20) (CG).

ELNE_HUMAN
NC score	0.052855 (rank : 201)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	64	Target Neighborhood Hits	164	Shared Neighborhood Hits	20
SwissProt Accessions	P08246, P09649, Q6B0D9, Q6LDP5	Gene names	ELA2
Domain Architecture
Description	Leukocyte elastase precursor (EC 3.4.21.37) (Elastase-2) (Neutrophil elastase) (PMN elastase) (Bone marrow serine protease) (Medullasin) (Human leukocyte elastase) (HLE).

K1B24_MOUSE
NC score	0.052824 (rank : 202)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	64	Target Neighborhood Hits	180	Shared Neighborhood Hits	20
SwissProt Accessions	Q61754, Q61755, Q9JM69	Gene names	Klk1b24, Klk-24, Klk24
Domain Architecture
Description	Kallikrein 1-related peptidase b24 precursor (EC 3.4.21.35) (Glandular kallikrein K24) (Tissue kallikrein 24) (mGK-24).

K1KB3_MOUSE
NC score	0.052761 (rank : 203)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	64	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	P00756	Gene names	Klk1b3, Klk-3, Klk3, Ngfg
Domain Architecture
Description	Kallikrein 1-related peptidase b3 precursor (EC 3.4.21.35) (Glandular kallikrein K3) (Tissue kallikrein-3) (mGK-3) (7S nerve growth factor gamma chain) (Gamma-NGF) [Contains: Nerve growth factor gamma chain 1; Nerve growth factor gamma chain 2].

MCPT4_MOUSE
NC score	0.052675 (rank : 204)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	P21812, Q9EPQ9, Q9EQT2	Gene names	Mcpt4
Domain Architecture
Description	Mast cell protease 4 precursor (EC 3.4.21.-) (MMCP-4) (Serosal mast cell protease) (MSMCP) (Myonase).

K1B27_MOUSE
NC score	0.052662 (rank : 205)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JM71	Gene names	Klk1b27, Klk-27, Klk27
Domain Architecture
Description	Kallikrein 1-related peptidase b27 precursor (EC 3.4.21.-) (Tissue kallikrein 27) (Glandular kallikrein K27) (mGK-27) (mKlk27).

K1B26_MOUSE
NC score	0.052525 (rank : 206)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P36369, P00753, P00754	Gene names	Klk1b26, Klk-26, Klk26
Domain Architecture
Description	Kallikrein 1-related peptidase b26 precursor (EC 3.4.21.35) (Glandular kallikrein K26) (Tissue kallikrein 26) (mGK-26) (Prorenin-converting enzyme 2) (PRECE-2).

KLK4_HUMAN
NC score	0.052432 (rank : 207)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y5K2, Q4VB16, Q9GZL6, Q9UBJ6	Gene names	KLK4, EMSP1, PRSS17, PSTS
Domain Architecture
Description	Kallikrein-4 precursor (EC 3.4.21.-) (Prostase) (Kallikrein-like protein 1) (KLK-L1) (Enamel matrix serine proteinase 1).

KLK1_MOUSE
NC score	0.052344 (rank : 208)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	64	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	P15947, Q61855	Gene names	Klk1, Klk-6, Klk6
Domain Architecture
Description	Glandular kallikrein K1 precursor (EC 3.4.21.35) (Tissue kallikrein-6) (mGK-6) (Renal kallikrein) (KAL-B).

K1KB5_MOUSE
NC score	0.052100 (rank : 209)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P15945, Q52KM1, Q565D7	Gene names	Klk1b5, Klk-5, Klk5
Domain Architecture
Description	Kallikrein 1-related peptidase b5 precursor (EC 3.4.21.35) (Glandular kallikrein K5) (Tissue kallikrein-5) (mGK-5).

EGFB2_MOUSE
NC score	0.051975 (rank : 210)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	P36368, P00754	Gene names	Egfbp2, Egfbp-2, Klk-13, Klk13
Domain Architecture
Description	Epidermal growth factor-binding protein type B precursor (EC 3.4.21.35) (EGF-BP B) (Glandular kallikrein K13) (Tissue kallikrein 13) (mGK-13) (Prorenin-converting enzyme) (PRECE).

PRTN3_HUMAN
NC score	0.051852 (rank : 211)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	P24158, P15637, P18078, Q6LBM7, Q9UQD8	Gene names	PRTN3, MBN
Domain Architecture
Description	Myeloblastin precursor (EC 3.4.21.76) (Leukocyte proteinase 3) (PR-3) (PR3) (AGP7) (Wegener autoantigen) (P29) (C-ANCA antigen) (Neutrophil proteinase 4) (NP-4).

K1B21_MOUSE
NC score	0.051836 (rank : 212)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	64	Target Neighborhood Hits	179	Shared Neighborhood Hits	20
SwissProt Accessions	Q61759, Q61760, Q9JM70	Gene names	Klk1b21, Klk-21, Klk21
Domain Architecture
Description	Kallikrein 1-related peptidase b21 precursor (EC 3.4.21.35) (Tissue kallikrein 21) (Glandular kallikrein K21) (mGK-21).

KLK2_HUMAN
NC score	0.051572 (rank : 213)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	64	Target Neighborhood Hits	176	Shared Neighborhood Hits	20
SwissProt Accessions	P20151, Q15946, Q9UJZ9	Gene names	KLK2
Domain Architecture
Description	Kallikrein-2 precursor (EC 3.4.21.35) (Tissue kallikrein-2) (Glandular kallikrein-1) (hGK-1).

K1KB8_MOUSE
NC score	0.051522 (rank : 214)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P07628	Gene names	Klk1b8, Klk-8, Klk8
Domain Architecture
Description	Kallikrein 1-related peptidase b8 precursor (EC 3.4.21.35) (Tissue kallikrein-8) (Glandular kallikrein K8) (mGK-8).

K1B22_MOUSE
NC score	0.051518 (rank : 215)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	64	Target Neighborhood Hits	174	Shared Neighborhood Hits	20
SwissProt Accessions	P15948	Gene names	Klk1b22, Klk-22, Klk22
Domain Architecture
Description	Kallikrein 1-related peptidase b22 precursor (EC 3.4.21.35) (Glandular kallikrein K22) (Tissue kallikrein 22) (mGK-22) (Epidermal growth factor-binding protein type A) (EGF-BP A) (Nerve growth factor beta chain endopeptidase) (Beta-NGF-endopeptidase).

CSMD3_HUMAN
NC score	0.051508 (rank : 216)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	64	Target Neighborhood Hits	199	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

GRAF_MOUSE
NC score	0.051505 (rank : 217)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	64	Target Neighborhood Hits	172	Shared Neighborhood Hits	20
SwissProt Accessions	P08883	Gene names	Gzmf, Ccp4, Ctla-7, Ctla7
Domain Architecture
Description	Granzyme F precursor (EC 3.4.21.-) (Cytotoxic cell protease 4) (CCP4) (CTL serine protease 3) (C134) (Cytotoxic serine protease 3) (MCSP3).

GRAG_MOUSE
NC score	0.051407 (rank : 218)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	64	Target Neighborhood Hits	173	Shared Neighborhood Hits	20
SwissProt Accessions	P13366, P97388	Gene names	Gzmg
Domain Architecture
Description	Granzyme G precursor (EC 3.4.21.-) (CTL serine protease 1) (MCSP-1).

DCBD2_HUMAN
NC score	0.051266 (rank : 219)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	64	Target Neighborhood Hits	118	Shared Neighborhood Hits	7
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

GRAE_MOUSE
NC score	0.051244 (rank : 220)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	64	Target Neighborhood Hits	172	Shared Neighborhood Hits	20
SwissProt Accessions	P08884, P97389	Gene names	Gzme, Ccp3, Ctla-6, Ctla6
Domain Architecture
Description	Granzyme E precursor (EC 3.4.21.-) (Cytotoxic cell protease 3) (CCP3) (CTL serine protease 2) (D12) (Cytotoxic serine protease 2) (MCSP2).

GRAH_HUMAN
NC score	0.050667 (rank : 221)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	P20718	Gene names	GZMH, CGL2, CTSGL2
Domain Architecture
Description	Granzyme H precursor (EC 3.4.21.-) (Cytotoxic T-lymphocyte proteinase) (Cathepsin G-like 2) (CTSGL2) (CCP-X) (Cytotoxic serine protease C) (CSP-C).

GRAD_MOUSE
NC score	0.050560 (rank : 222)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	64	Target Neighborhood Hits	173	Shared Neighborhood Hits	20
SwissProt Accessions	P11033, P97387	Gene names	Gzmd
Domain Architecture
Description	Granzyme D precursor (EC 3.4.21.-).

K1KB4_MOUSE
NC score	0.050431 (rank : 223)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P00757	Gene names	Klk1b4, Klk-4, Klk4, Ngfa
Domain Architecture
Description	Kallikrein 1-related peptidase-like b4 precursor (7S nerve growth factor alpha chain) (Alpha-NGF).

TECTA_MOUSE
NC score	0.050289 (rank : 224)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	64	Target Neighborhood Hits	244	Shared Neighborhood Hits	13
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

CSMD1_MOUSE
NC score	0.050216 (rank : 225)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	64	Target Neighborhood Hits	193	Shared Neighborhood Hits	12
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

GRAC_MOUSE
NC score	0.050192 (rank : 226)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	64	Target Neighborhood Hits	177	Shared Neighborhood Hits	20
SwissProt Accessions	P08882, Q61389	Gene names	Gzmc, Ctla-5, Ctla5
Domain Architecture
Description	Granzyme C precursor (EC 3.4.21.-) (Cytotoxic cell protease 2) (CCP2) (B10).

KLK1_HUMAN
NC score	0.050140 (rank : 227)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	64	Target Neighborhood Hits	183	Shared Neighborhood Hits	20
SwissProt Accessions	P06870, Q8TCV8, Q9BS53, Q9NQU4, Q9UMJ1	Gene names	KLK1
Domain Architecture
Description	Kallikrein-1 precursor (EC 3.4.21.35) (Tissue kallikrein) (Kidney/pancreas/salivary gland kallikrein).

MCPT2_MOUSE
NC score	0.050033 (rank : 228)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	64	Target Neighborhood Hits	175	Shared Neighborhood Hits	20
SwissProt Accessions	P15119	Gene names	Mcpt2
Domain Architecture
Description	Mast cell protease 2 precursor (EC 3.4.21.-) (MMCP-2).

NRP2_MOUSE
NC score	0.050028 (rank : 229)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	64	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

UROM_HUMAN
NC score	0.045404 (rank : 230)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	64	Target Neighborhood Hits	284	Shared Neighborhood Hits	16
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

GLUD1_MOUSE
NC score	0.034145 (rank : 231)	θ value	0.125558 (rank : 36)
Query Neighborhood Hits	64	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CIX8	Gene names	Gluld1, Lgs
Domain Architecture	No domain graphic available
Description	Glutamate--ammonia ligase domain-containing protein 1 (Lengsin) (Lens glutamine synthase-like).

ATRN_HUMAN
NC score	0.032329 (rank : 232)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	64	Target Neighborhood Hits	525	Shared Neighborhood Hits	13
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

K0133_HUMAN
NC score	0.021866 (rank : 233)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	64	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q14146	Gene names	KIAA0133
Domain Architecture	No domain graphic available
Description	Protein KIAA0133.

LRP1_HUMAN
NC score	0.017653 (rank : 234)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	64	Target Neighborhood Hits	617	Shared Neighborhood Hits	29
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP4_MOUSE
NC score	0.016460 (rank : 235)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	64	Target Neighborhood Hits	351	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

K1267_HUMAN
NC score	0.016294 (rank : 236)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	64	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z3B3, Q6AW85, Q8IYH1, Q9NTE7, Q9UFT0, Q9ULF3	Gene names	KIAA1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

CDYL_MOUSE
NC score	0.014126 (rank : 237)	θ value	0.47712 (rank : 40)
Query Neighborhood Hits	64	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WTK2	Gene names	Cdyl
Domain Architecture
Description	Chromodomain Y-like protein (CDY-like).

K1267_MOUSE
NC score	0.012937 (rank : 238)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	64	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q80TG1, Q3TT88, Q3U5D8, Q3V3N3, Q7TMU3, Q80XP7, Q8R3L6, Q9D9G0	Gene names	Kiaa1267
Domain Architecture	No domain graphic available
Description	Protein KIAA1267.

EXO1_MOUSE
NC score	0.012624 (rank : 239)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	64	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZ11, Q3TLM4, Q923A5	Gene names	Exo1
Domain Architecture	No domain graphic available
Description	Exonuclease 1 (EC 3.1.-.-) (mExo1) (Exonuclease I).

CD248_HUMAN
NC score	0.012381 (rank : 240)	θ value	0.365318 (rank : 38)
Query Neighborhood Hits	64	Target Neighborhood Hits	679	Shared Neighborhood Hits	14
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

S22A3_MOUSE
NC score	0.011867 (rank : 241)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	64	Target Neighborhood Hits	50	Shared Neighborhood Hits	2
SwissProt Accessions	Q9WTW5, Q9R209	Gene names	Slc22a3, Oct3
Domain Architecture
Description	Organic cation transporter 3 (Solute carrier family 22 member 3).

SYP2L_HUMAN
NC score	0.008001 (rank : 242)	θ value	2.36792 (rank : 50)
Query Neighborhood Hits	64	Target Neighborhood Hits	400	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H987	Gene names	SYNPO2L
Domain Architecture	No domain graphic available
Description	Synaptopodin 2-like protein.

LTBP2_MOUSE
NC score	0.007273 (rank : 243)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	64	Target Neighborhood Hits	617	Shared Neighborhood Hits	15
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LAMC1_MOUSE
NC score	0.006827 (rank : 244)	θ value	0.813845 (rank : 42)
Query Neighborhood Hits	64	Target Neighborhood Hits	856	Shared Neighborhood Hits	12
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LMA1L_MOUSE
NC score	0.005744 (rank : 245)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	64	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VCD3	Gene names	Lman1l, Ergl
Domain Architecture
Description	ERGIC-53-like protein precursor (ERGIC53-like protein) (Lectin, mannose-binding 1-like) (LMAN1-like protein).

EGF_MOUSE
NC score	0.004903 (rank : 246)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	64	Target Neighborhood Hits	358	Shared Neighborhood Hits	12
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

BAI3_HUMAN
NC score	0.004149 (rank : 247)	θ value	1.81305 (rank : 46)
Query Neighborhood Hits	64	Target Neighborhood Hits	246	Shared Neighborhood Hits	3
SwissProt Accessions	O60242, O60297	Gene names	BAI3, KIAA0550
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 3 precursor.

LAMA2_MOUSE
NC score	0.003265 (rank : 248)	θ value	4.03905 (rank : 53)
Query Neighborhood Hits	64	Target Neighborhood Hits	1198	Shared Neighborhood Hits	16
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

CR1_HUMAN
NC score	0.002888 (rank : 249)	θ value	8.99809 (rank : 60)
Query Neighborhood Hits	64	Target Neighborhood Hits	108	Shared Neighborhood Hits	6
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

SPG16_HUMAN
NC score	0.002808 (rank : 250)	θ value	2.36792 (rank : 49)
Query Neighborhood Hits	64	Target Neighborhood Hits	361	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N0X2, Q658W1, Q68DB3, Q6I9Z6, Q8N9C7, Q9H601	Gene names	SPAG16, PF20
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 16 protein (PF20 protein homolog).

AD26A_MOUSE
NC score	0.001917 (rank : 251)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	64	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R158	Gene names	Adam26a, Adam26
Domain Architecture
Description	ADAM 26A precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 26A) (Testase-3).