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Network neighborhood for query Sequence : CD6_HUMAN

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CD6_HUMAN
SwissProt Accessions	P30203, Q9UMF2, Q9Y4K7, Q9Y4K8, Q9Y4K9, Q9Y4L0	Gene names	CD6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor (T12) (TP120).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CD6_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	P30203, Q9UMF2, Q9Y4K7, Q9Y4K8, Q9Y4K9, Q9Y4L0	Gene names	CD6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor (T12) (TP120).

CD6_MOUSE
θ value	0 (rank : 2)	NC score	0.992618 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	62	Shared Neighborhood Hits	37
SwissProt Accessions	Q61003, Q60679, Q61004	Gene names	Cd6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor.

DMBT1_HUMAN
θ value	6.53529e-67 (rank : 3)	NC score	0.744530 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	152	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DMBT1_MOUSE
θ value	7.24236e-58 (rank : 4)	NC score	0.675898 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	134	Shared Neighborhood Hits	30
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

C163A_MOUSE
θ value	1.01294e-51 (rank : 5)	NC score	0.912961 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	48	Shared Neighborhood Hits	30
SwissProt Accessions	Q2VLH6, Q2VLH5, Q99MX8	Gene names	Cd163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) [Contains: Soluble CD163 (sCD163)].

C163A_HUMAN
θ value	2.25659e-51 (rank : 6)	NC score	0.911338 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	54	Shared Neighborhood Hits	30
SwissProt Accessions	Q86VB7, Q07898, Q07899, Q07900, Q07901, Q2VLH7	Gene names	CD163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) (Hemoglobin scavenger receptor) [Contains: Soluble CD163 (sCD163)].

C163B_HUMAN
θ value	2.25659e-51 (rank : 7)	NC score	0.909177 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	64	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

CD5L_HUMAN
θ value	6.14528e-49 (rank : 8)	NC score	0.936369 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	O43866, Q6UX63	Gene names	CD5L
Domain Architecture
Description	CD5 antigen-like precursor (SP-alpha) (CT-2) (IgM-associated peptide).

NETR_HUMAN
θ value	1.12253e-42 (rank : 9)	NC score	0.437952 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	218	Shared Neighborhood Hits	33
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

CD5L_MOUSE
θ value	3.61106e-41 (rank : 10)	NC score	0.931126 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	49	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QWK4, O35300, O35301, Q505P6, Q91W05	Gene names	Cd5l, Aim, Api6
Domain Architecture
Description	CD5 antigen-like precursor (SP-alpha) (CT-2) (Apoptosis inhibitory 6) (Apoptosis inhibitor expressed by macrophages).

NETR_MOUSE
θ value	1.32909e-35 (rank : 11)	NC score	0.423049 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	216	Shared Neighborhood Hits	33
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

LOXL3_MOUSE
θ value	4.27553e-34 (rank : 12)	NC score	0.804399 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z175, Q9JJ39	Gene names	Loxl3, Lor2
Domain Architecture
Description	Lysyl oxidase homolog 3 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 3) (Lysyl oxidase-related protein 2).

LOXL2_MOUSE
θ value	7.29293e-34 (rank : 13)	NC score	0.806213 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	44	Shared Neighborhood Hits	29
SwissProt Accessions	P58022, Q8BRE6, Q8BS86, Q8C4K0, Q9JJ39	Gene names	Loxl2
Domain Architecture	No domain graphic available
Description	Lysyl oxidase homolog 2 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 2).

LOXL3_HUMAN
θ value	8.91499e-32 (rank : 14)	NC score	0.801097 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	47	Shared Neighborhood Hits	29
SwissProt Accessions	P58215, Q96RS1	Gene names	LOXL3, LOXL
Domain Architecture
Description	Lysyl oxidase homolog 3 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 3).

LOXL4_HUMAN
θ value	8.91499e-32 (rank : 15)	NC score	0.802600 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	Q96JB6, Q96DY1, Q96PC0, Q9H6T5	Gene names	LOXL4, LOXC
Domain Architecture
Description	Lysyl oxidase homolog 4 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 4) (Lysyl oxidase-related protein C).

LOXL2_HUMAN
θ value	9.8567e-31 (rank : 16)	NC score	0.802122 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	49	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y4K0, Q9BW70, Q9Y5Y8	Gene names	LOXL2
Domain Architecture
Description	Lysyl oxidase homolog 2 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 2) (Lysyl oxidase-related protein 2) (Lysyl oxidase-related protein WS9-14).

LOXL4_MOUSE
θ value	1.4233e-29 (rank : 17)	NC score	0.801757 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	Q924C6	Gene names	Loxl4, Loxc
Domain Architecture
Description	Lysyl oxidase homolog 4 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 4) (Lysyl oxidase-related protein C).

LG3BP_HUMAN
θ value	3.75424e-22 (rank : 18)	NC score	0.840434 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	67	Shared Neighborhood Hits	28
SwissProt Accessions	Q08380	Gene names	LGALS3BP, M2BP
Domain Architecture
Description	Galectin-3-binding protein precursor (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (Mac-2 BP) (MAC2BP) (Tumor-associated antigen 90K).

MSRE_MOUSE
θ value	4.29542e-18 (rank : 19)	NC score	0.656788 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	307	Shared Neighborhood Hits	29
SwissProt Accessions	P30204, Q923G0, Q9QZ56	Gene names	Msr1, Scvr
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor type A) (SR-A).

MSRE_HUMAN
θ value	2.7842e-17 (rank : 20)	NC score	0.598152 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	298	Shared Neighborhood Hits	29
SwissProt Accessions	P21757, P21759, Q45F10	Gene names	MSR1, SCARA1
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor class A member 1) (CD204 antigen).

MARCO_MOUSE
θ value	8.10077e-17 (rank : 21)	NC score	0.411170 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	242	Shared Neighborhood Hits	29
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

MARCO_HUMAN
θ value	8.38298e-14 (rank : 22)	NC score	0.508574 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	199	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UEW3, Q9Y5S3	Gene names	MARCO, SCARA2
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2).

CD5_MOUSE
θ value	4.59992e-12 (rank : 23)	NC score	0.622636 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	33	Shared Neighborhood Hits	24
SwissProt Accessions	P13379	Gene names	Cd5, Ly-1
Domain Architecture
Description	T-cell surface glycoprotein CD5 precursor (Lymphocyte antigen Ly-1) (Lyt-1).

CD5_HUMAN
θ value	1.38499e-08 (rank : 24)	NC score	0.581679 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	P06127	Gene names	CD5, LEU1
Domain Architecture
Description	T-cell surface glycoprotein CD5 precursor (Lymphocyte antigen T1/Leu- 1).

ENTK_MOUSE
θ value	0.000121331 (rank : 25)	NC score	0.116889 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	338	Shared Neighborhood Hits	28
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ENTK_HUMAN
θ value	0.00228821 (rank : 26)	NC score	0.103410 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	310	Shared Neighborhood Hits	30
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

SYNP2_MOUSE
θ value	0.0113563 (rank : 27)	NC score	0.036600 (rank : 89)
Query Neighborhood Hits	65	Target Neighborhood Hits	252	Shared Neighborhood Hits	7
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

RGS3_MOUSE
θ value	0.0961366 (rank : 28)	NC score	0.013648 (rank : 98)
Query Neighborhood Hits	65	Target Neighborhood Hits	1621	Shared Neighborhood Hits	17
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

CFAI_MOUSE
θ value	0.163984 (rank : 29)	NC score	0.111972 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	290	Shared Neighborhood Hits	28
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

HSH2D_MOUSE
θ value	0.365318 (rank : 30)	NC score	0.026346 (rank : 91)
Query Neighborhood Hits	65	Target Neighborhood Hits	124	Shared Neighborhood Hits	2
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

CETP_HUMAN
θ value	0.813845 (rank : 31)	NC score	0.029323 (rank : 90)
Query Neighborhood Hits	65	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P11597, Q13987, Q13988	Gene names	CETP
Domain Architecture
Description	Cholesteryl ester transfer protein precursor (Lipid transfer protein I).

TMPSD_MOUSE
θ value	0.813845 (rank : 32)	NC score	0.076885 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	334	Shared Neighborhood Hits	31
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

DMRTD_HUMAN
θ value	1.06291 (rank : 33)	NC score	0.021017 (rank : 94)
Query Neighborhood Hits	65	Target Neighborhood Hits	216	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

SOS1_HUMAN
θ value	1.38821 (rank : 34)	NC score	0.011596 (rank : 100)
Query Neighborhood Hits	65	Target Neighborhood Hits	274	Shared Neighborhood Hits	7
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

ADA12_HUMAN
θ value	1.81305 (rank : 35)	NC score	0.009652 (rank : 104)
Query Neighborhood Hits	65	Target Neighborhood Hits	224	Shared Neighborhood Hits	5
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

IF4B_MOUSE
θ value	1.81305 (rank : 36)	NC score	0.022343 (rank : 92)
Query Neighborhood Hits	65	Target Neighborhood Hits	368	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

ADA12_MOUSE
θ value	2.36792 (rank : 37)	NC score	0.008371 (rank : 107)
Query Neighborhood Hits	65	Target Neighborhood Hits	474	Shared Neighborhood Hits	8
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

AMPD3_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.018481 (rank : 95)
Query Neighborhood Hits	65	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q01432	Gene names	AMPD3
Domain Architecture
Description	AMP deaminase 3 (EC 3.5.4.6) (AMP deaminase isoform E) (Erythrocyte AMP deaminase).

AMPD3_MOUSE
θ value	2.36792 (rank : 39)	NC score	0.021827 (rank : 93)
Query Neighborhood Hits	65	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	O08739, O88692	Gene names	Ampd3
Domain Architecture
Description	AMP deaminase 3 (EC 3.5.4.6) (AMP deaminase isoform E) (AMP deaminase H-type) (Heart-type AMPD).

CSPG2_HUMAN
θ value	2.36792 (rank : 40)	NC score	0.004296 (rank : 113)
Query Neighborhood Hits	65	Target Neighborhood Hits	681	Shared Neighborhood Hits	4
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

MLL3_HUMAN
θ value	2.36792 (rank : 41)	NC score	0.010636 (rank : 102)
Query Neighborhood Hits	65	Target Neighborhood Hits	1644	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

CENPC_HUMAN
θ value	3.0926 (rank : 42)	NC score	0.015274 (rank : 97)
Query Neighborhood Hits	65	Target Neighborhood Hits	147	Shared Neighborhood Hits	2
SwissProt Accessions	Q03188, Q9P0M5	Gene names	CENPC1, CENPC, ICEN7
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C) (Interphase centromere complex protein 7).

LTBP2_HUMAN
θ value	3.0926 (rank : 43)	NC score	0.003109 (rank : 115)
Query Neighborhood Hits	65	Target Neighborhood Hits	552	Shared Neighborhood Hits	9
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

PRRT3_HUMAN
θ value	3.0926 (rank : 44)	NC score	0.008272 (rank : 108)
Query Neighborhood Hits	65	Target Neighborhood Hits	998	Shared Neighborhood Hits	12
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SON_MOUSE
θ value	3.0926 (rank : 45)	NC score	0.017595 (rank : 96)
Query Neighborhood Hits	65	Target Neighborhood Hits	957	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

EFHD1_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.010519 (rank : 103)
Query Neighborhood Hits	65	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D4J1, Q543U4	Gene names	Efhd1, Sws2
Domain Architecture
Description	EF-hand domain-containing protein 1 (Swiprosin-2).

GRN_HUMAN
θ value	4.03905 (rank : 47)	NC score	0.009338 (rank : 105)
Query Neighborhood Hits	65	Target Neighborhood Hits	268	Shared Neighborhood Hits	4
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

MLL3_MOUSE
θ value	4.03905 (rank : 48)	NC score	0.010637 (rank : 101)
Query Neighborhood Hits	65	Target Neighborhood Hits	1399	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

PLXB1_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.005402 (rank : 112)
Query Neighborhood Hits	65	Target Neighborhood Hits	360	Shared Neighborhood Hits	5
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

BICD1_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.000626 (rank : 117)
Query Neighborhood Hits	65	Target Neighborhood Hits	844	Shared Neighborhood Hits	2
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

MKL1_MOUSE
θ value	5.27518 (rank : 51)	NC score	0.009120 (rank : 106)
Query Neighborhood Hits	65	Target Neighborhood Hits	667	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

NUPL2_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.013646 (rank : 99)
Query Neighborhood Hits	65	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CIC2, Q8BJX3, Q8BVP7, Q924S0	Gene names	Nupl2
Domain Architecture	No domain graphic available
Description	Nucleoporin-like 2 (NLP-1).

HXC10_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.001819 (rank : 116)
Query Neighborhood Hits	65	Target Neighborhood Hits	417	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYD6, O15219, O15220, Q9BVD5	Gene names	HOXC10
Domain Architecture
Description	Homeobox protein Hox-C10.

MARK4_HUMAN
θ value	6.88961 (rank : 54)	NC score	-0.003366 (rank : 120)
Query Neighborhood Hits	65	Target Neighborhood Hits	886	Shared Neighborhood Hits	5
SwissProt Accessions	Q96L34, Q8NG37, Q96JG7, Q96SQ2, Q9BYD8	Gene names	MARK4, KIAA1860, MARKL1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1).

SPEG_MOUSE
θ value	6.88961 (rank : 55)	NC score	-0.002405 (rank : 118)
Query Neighborhood Hits	65	Target Neighborhood Hits	1959	Shared Neighborhood Hits	13
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TMPS2_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.058686 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	252	Shared Neighborhood Hits	21
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS2_MOUSE
θ value	6.88961 (rank : 57)	NC score	0.049233 (rank : 88)
Query Neighborhood Hits	65	Target Neighborhood Hits	243	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

TMPS3_MOUSE
θ value	6.88961 (rank : 58)	NC score	0.079026 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	239	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

TMPS5_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.059719 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	185	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

ZN366_HUMAN
θ value	6.88961 (rank : 60)	NC score	-0.003206 (rank : 119)
Query Neighborhood Hits	65	Target Neighborhood Hits	732	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N895, Q7RTV4	Gene names	ZNF366
Domain Architecture	No domain graphic available
Description	Zinc finger protein 366.

FGD5_HUMAN
θ value	8.99809 (rank : 61)	NC score	0.003315 (rank : 114)
Query Neighborhood Hits	65	Target Neighborhood Hits	235	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

LCP2_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.007420 (rank : 109)
Query Neighborhood Hits	65	Target Neighborhood Hits	531	Shared Neighborhood Hits	9
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

PAX2_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.006855 (rank : 111)
Query Neighborhood Hits	65	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	P32114	Gene names	Pax2, Pax-2
Domain Architecture
Description	Paired box protein Pax-2.

SFR14_MOUSE
θ value	8.99809 (rank : 64)	NC score	0.006906 (rank : 110)
Query Neighborhood Hits	65	Target Neighborhood Hits	238	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CH09, Q6PG19, Q80UY8, Q8BY32, Q8CFM0	Gene names	Sfrs14
Domain Architecture	No domain graphic available
Description	Putative splicing factor, arginine/serine-rich 14 (Arginine/serine- rich-splicing factor 14).

ZN606_HUMAN
θ value	8.99809 (rank : 65)	NC score	-0.003670 (rank : 121)
Query Neighborhood Hits	65	Target Neighborhood Hits	749	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXB4, Q8NE04, Q96JH5	Gene names	ZNF606, KIAA1852, ZNF328
Domain Architecture
Description	Zinc finger protein 606 (Zinc finger protein 328).

BMP1_HUMAN
θ value	θ > 10 (rank : 66)	NC score	0.054873 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	233	Shared Neighborhood Hits	5
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 67)	NC score	0.055147 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	236	Shared Neighborhood Hits	5
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

C1RA_MOUSE
θ value	θ > 10 (rank : 68)	NC score	0.052508 (rank : 82)
Query Neighborhood Hits	65	Target Neighborhood Hits	379	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	θ > 10 (rank : 69)	NC score	0.053321 (rank : 74)
Query Neighborhood Hits	65	Target Neighborhood Hits	380	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1R_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.053948 (rank : 71)
Query Neighborhood Hits	65	Target Neighborhood Hits	364	Shared Neighborhood Hits	13
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

C1S_HUMAN
θ value	θ > 10 (rank : 71)	NC score	0.056322 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	359	Shared Neighborhood Hits	13
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CFAI_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.108825 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	289	Shared Neighborhood Hits	29
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CORIN_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.058230 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	451	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CS1A_MOUSE
θ value	θ > 10 (rank : 74)	NC score	0.056428 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	360	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
θ value	θ > 10 (rank : 75)	NC score	0.057244 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	361	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CUZD1_HUMAN
θ value	θ > 10 (rank : 76)	NC score	0.112888 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUZD1_MOUSE
θ value	θ > 10 (rank : 77)	NC score	0.116962 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	91	Shared Neighborhood Hits	4
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

KREM1_MOUSE
θ value	θ > 10 (rank : 78)	NC score	0.051867 (rank : 84)
Query Neighborhood Hits	65	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

LOXL1_HUMAN
θ value	θ > 10 (rank : 79)	NC score	0.267108 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q08397, Q96BW7	Gene names	LOXL1, LOXL
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (LOL).

LOXL1_MOUSE
θ value	θ > 10 (rank : 80)	NC score	0.266159 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	P97873, Q91ZY4, Q99KX3	Gene names	Loxl1, Lox2, Loxl
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (Lysyl oxidase 2).

LRP12_HUMAN
θ value	θ > 10 (rank : 81)	NC score	0.053113 (rank : 76)
Query Neighborhood Hits	65	Target Neighborhood Hits	205	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 82)	NC score	0.053213 (rank : 75)
Query Neighborhood Hits	65	Target Neighborhood Hits	180	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LYOX_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.280600 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P28300, Q5FWF0	Gene names	LOX
Domain Architecture
Description	Protein-lysine 6-oxidase precursor (EC 1.4.3.13) (Lysyl oxidase).

LYOX_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.278459 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	P28301	Gene names	Lox, Rrg
Domain Architecture
Description	Protein-lysine 6-oxidase precursor (EC 1.4.3.13) (Lysyl oxidase) (RAS excision protein).

MASP1_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.057179 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	369	Shared Neighborhood Hits	13
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.056448 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	364	Shared Neighborhood Hits	13
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MASP2_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.055570 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	364	Shared Neighborhood Hits	13
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.052893 (rank : 78)
Query Neighborhood Hits	65	Target Neighborhood Hits	382	Shared Neighborhood Hits	13
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MFRP_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.052553 (rank : 81)
Query Neighborhood Hits	65	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.053418 (rank : 73)
Query Neighborhood Hits	65	Target Neighborhood Hits	166	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

NETO1_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.052193 (rank : 83)
Query Neighborhood Hits	65	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.051669 (rank : 85)
Query Neighborhood Hits	65	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.053901 (rank : 72)
Query Neighborhood Hits	65	Target Neighborhood Hits	109	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.054125 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

PCOC1_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.056014 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	146	Shared Neighborhood Hits	5
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.056853 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 97)	NC score	0.062700 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.063634 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

ST14_HUMAN
θ value	θ > 10 (rank : 99)	NC score	0.061045 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	409	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ST14_MOUSE
θ value	θ > 10 (rank : 100)	NC score	0.062864 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	419	Shared Neighborhood Hits	13
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

TECTB_HUMAN
θ value	θ > 10 (rank : 101)	NC score	0.054123 (rank : 69)
Query Neighborhood Hits	65	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q96PL2	Gene names	TECTB
Domain Architecture
Description	Beta-tectorin precursor.

TECTB_MOUSE
θ value	θ > 10 (rank : 102)	NC score	0.054154 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	O08524	Gene names	Tectb
Domain Architecture
Description	Beta-tectorin precursor.

TGBR3_HUMAN
θ value	θ > 10 (rank : 103)	NC score	0.054441 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q03167, Q5T2T4, Q5U731, Q9UGI2	Gene names	TGFBR3
Domain Architecture
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

TGBR3_MOUSE
θ value	θ > 10 (rank : 104)	NC score	0.053027 (rank : 77)
Query Neighborhood Hits	65	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	O88393, Q6NS72	Gene names	Tgfbr3
Domain Architecture	No domain graphic available
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

TLL1_HUMAN
θ value	θ > 10 (rank : 105)	NC score	0.058971 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	236	Shared Neighborhood Hits	6
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 106)	NC score	0.059921 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	237	Shared Neighborhood Hits	6
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.057251 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	241	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.058006 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	240	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TMPS3_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.081672 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	245	Shared Neighborhood Hits	29
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

TMPS4_HUMAN
θ value	θ > 10 (rank : 110)	NC score	0.050309 (rank : 87)
Query Neighborhood Hits	65	Target Neighborhood Hits	203	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

TMPS4_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.060593 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	210	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

TMPS5_HUMAN
θ value	θ > 10 (rank : 112)	NC score	0.052839 (rank : 79)
Query Neighborhood Hits	65	Target Neighborhood Hits	181	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TMPS7_HUMAN
θ value	θ > 10 (rank : 113)	NC score	0.053992 (rank : 70)
Query Neighborhood Hits	65	Target Neighborhood Hits	275	Shared Neighborhood Hits	13
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS7_MOUSE
θ value	θ > 10 (rank : 114)	NC score	0.051470 (rank : 86)
Query Neighborhood Hits	65	Target Neighborhood Hits	275	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPSD_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.057142 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	333	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

TSG6_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.059809 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	91	Shared Neighborhood Hits	5
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.059791 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	91	Shared Neighborhood Hits	5
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

ZP2_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.063075 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q05996	Gene names	ZP2, ZPA
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

ZP2_MOUSE
θ value	θ > 10 (rank : 119)	NC score	0.057638 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	P20239	Gene names	Zp2, Zp-2, Zpa
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

ZP3_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.052726 (rank : 80)
Query Neighborhood Hits	65	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P10761	Gene names	Zp3, Zp-3, Zpc
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 precursor (Zona pellucida glycoprotein ZP3) (Sperm receptor) (Zona pellucida protein C).

ZP4_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.056013 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q12836	Gene names	ZP4, ZPB
Domain Architecture
Description	Zona pellucida sperm-binding protein 4 precursor (Zona pellucida sperm-binding protein B).

Hits sorted by NC score

CD6_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	65	Target Neighborhood Hits	65	Shared Neighborhood Hits	65
SwissProt Accessions	P30203, Q9UMF2, Q9Y4K7, Q9Y4K8, Q9Y4K9, Q9Y4L0	Gene names	CD6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor (T12) (TP120).

CD6_MOUSE
NC score	0.992618 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	65	Target Neighborhood Hits	62	Shared Neighborhood Hits	37
SwissProt Accessions	Q61003, Q60679, Q61004	Gene names	Cd6
Domain Architecture
Description	T-cell differentiation antigen CD6 precursor.

CD5L_HUMAN
NC score	0.936369 (rank : 3)	θ value	6.14528e-49 (rank : 8)
Query Neighborhood Hits	65	Target Neighborhood Hits	45	Shared Neighborhood Hits	30
SwissProt Accessions	O43866, Q6UX63	Gene names	CD5L
Domain Architecture
Description	CD5 antigen-like precursor (SP-alpha) (CT-2) (IgM-associated peptide).

CD5L_MOUSE
NC score	0.931126 (rank : 4)	θ value	3.61106e-41 (rank : 10)
Query Neighborhood Hits	65	Target Neighborhood Hits	49	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QWK4, O35300, O35301, Q505P6, Q91W05	Gene names	Cd5l, Aim, Api6
Domain Architecture
Description	CD5 antigen-like precursor (SP-alpha) (CT-2) (Apoptosis inhibitory 6) (Apoptosis inhibitor expressed by macrophages).

C163A_MOUSE
NC score	0.912961 (rank : 5)	θ value	1.01294e-51 (rank : 5)
Query Neighborhood Hits	65	Target Neighborhood Hits	48	Shared Neighborhood Hits	30
SwissProt Accessions	Q2VLH6, Q2VLH5, Q99MX8	Gene names	Cd163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) [Contains: Soluble CD163 (sCD163)].

C163A_HUMAN
NC score	0.911338 (rank : 6)	θ value	2.25659e-51 (rank : 6)
Query Neighborhood Hits	65	Target Neighborhood Hits	54	Shared Neighborhood Hits	30
SwissProt Accessions	Q86VB7, Q07898, Q07899, Q07900, Q07901, Q2VLH7	Gene names	CD163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) (Hemoglobin scavenger receptor) [Contains: Soluble CD163 (sCD163)].

C163B_HUMAN
NC score	0.909177 (rank : 7)	θ value	2.25659e-51 (rank : 7)
Query Neighborhood Hits	65	Target Neighborhood Hits	64	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NR16, Q6UWC2	Gene names	CD163L1, CD163B, M160
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M160 precursor (CD163 antigen-like 1) (CD163b antigen).

LG3BP_HUMAN
NC score	0.840434 (rank : 8)	θ value	3.75424e-22 (rank : 18)
Query Neighborhood Hits	65	Target Neighborhood Hits	67	Shared Neighborhood Hits	28
SwissProt Accessions	Q08380	Gene names	LGALS3BP, M2BP
Domain Architecture
Description	Galectin-3-binding protein precursor (Lectin galactoside-binding soluble 3-binding protein) (Mac-2-binding protein) (Mac-2 BP) (MAC2BP) (Tumor-associated antigen 90K).

LOXL2_MOUSE
NC score	0.806213 (rank : 9)	θ value	7.29293e-34 (rank : 13)
Query Neighborhood Hits	65	Target Neighborhood Hits	44	Shared Neighborhood Hits	29
SwissProt Accessions	P58022, Q8BRE6, Q8BS86, Q8C4K0, Q9JJ39	Gene names	Loxl2
Domain Architecture	No domain graphic available
Description	Lysyl oxidase homolog 2 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 2).

LOXL3_MOUSE
NC score	0.804399 (rank : 10)	θ value	4.27553e-34 (rank : 12)
Query Neighborhood Hits	65	Target Neighborhood Hits	48	Shared Neighborhood Hits	29
SwissProt Accessions	Q9Z175, Q9JJ39	Gene names	Loxl3, Lor2
Domain Architecture
Description	Lysyl oxidase homolog 3 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 3) (Lysyl oxidase-related protein 2).

LOXL4_HUMAN
NC score	0.802600 (rank : 11)	θ value	8.91499e-32 (rank : 15)
Query Neighborhood Hits	65	Target Neighborhood Hits	43	Shared Neighborhood Hits	30
SwissProt Accessions	Q96JB6, Q96DY1, Q96PC0, Q9H6T5	Gene names	LOXL4, LOXC
Domain Architecture
Description	Lysyl oxidase homolog 4 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 4) (Lysyl oxidase-related protein C).

LOXL2_HUMAN
NC score	0.802122 (rank : 12)	θ value	9.8567e-31 (rank : 16)
Query Neighborhood Hits	65	Target Neighborhood Hits	49	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Y4K0, Q9BW70, Q9Y5Y8	Gene names	LOXL2
Domain Architecture
Description	Lysyl oxidase homolog 2 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 2) (Lysyl oxidase-related protein 2) (Lysyl oxidase-related protein WS9-14).

LOXL4_MOUSE
NC score	0.801757 (rank : 13)	θ value	1.4233e-29 (rank : 17)
Query Neighborhood Hits	65	Target Neighborhood Hits	50	Shared Neighborhood Hits	29
SwissProt Accessions	Q924C6	Gene names	Loxl4, Loxc
Domain Architecture
Description	Lysyl oxidase homolog 4 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 4) (Lysyl oxidase-related protein C).

LOXL3_HUMAN
NC score	0.801097 (rank : 14)	θ value	8.91499e-32 (rank : 14)
Query Neighborhood Hits	65	Target Neighborhood Hits	47	Shared Neighborhood Hits	29
SwissProt Accessions	P58215, Q96RS1	Gene names	LOXL3, LOXL
Domain Architecture
Description	Lysyl oxidase homolog 3 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 3).

DMBT1_HUMAN
NC score	0.744530 (rank : 15)	θ value	6.53529e-67 (rank : 3)
Query Neighborhood Hits	65	Target Neighborhood Hits	152	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DMBT1_MOUSE
NC score	0.675898 (rank : 16)	θ value	7.24236e-58 (rank : 4)
Query Neighborhood Hits	65	Target Neighborhood Hits	134	Shared Neighborhood Hits	30
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

MSRE_MOUSE
NC score	0.656788 (rank : 17)	θ value	4.29542e-18 (rank : 19)
Query Neighborhood Hits	65	Target Neighborhood Hits	307	Shared Neighborhood Hits	29
SwissProt Accessions	P30204, Q923G0, Q9QZ56	Gene names	Msr1, Scvr
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor type A) (SR-A).

CD5_MOUSE
NC score	0.622636 (rank : 18)	θ value	4.59992e-12 (rank : 23)
Query Neighborhood Hits	65	Target Neighborhood Hits	33	Shared Neighborhood Hits	24
SwissProt Accessions	P13379	Gene names	Cd5, Ly-1
Domain Architecture
Description	T-cell surface glycoprotein CD5 precursor (Lymphocyte antigen Ly-1) (Lyt-1).

MSRE_HUMAN
NC score	0.598152 (rank : 19)	θ value	2.7842e-17 (rank : 20)
Query Neighborhood Hits	65	Target Neighborhood Hits	298	Shared Neighborhood Hits	29
SwissProt Accessions	P21757, P21759, Q45F10	Gene names	MSR1, SCARA1
Domain Architecture
Description	Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor class A member 1) (CD204 antigen).

CD5_HUMAN
NC score	0.581679 (rank : 20)	θ value	1.38499e-08 (rank : 24)
Query Neighborhood Hits	65	Target Neighborhood Hits	36	Shared Neighborhood Hits	22
SwissProt Accessions	P06127	Gene names	CD5, LEU1
Domain Architecture
Description	T-cell surface glycoprotein CD5 precursor (Lymphocyte antigen T1/Leu- 1).

MARCO_HUMAN
NC score	0.508574 (rank : 21)	θ value	8.38298e-14 (rank : 22)
Query Neighborhood Hits	65	Target Neighborhood Hits	199	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UEW3, Q9Y5S3	Gene names	MARCO, SCARA2
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2).

NETR_HUMAN
NC score	0.437952 (rank : 22)	θ value	1.12253e-42 (rank : 9)
Query Neighborhood Hits	65	Target Neighborhood Hits	218	Shared Neighborhood Hits	33
SwissProt Accessions	P56730, Q9UP16	Gene names	PRSS12
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Leydin).

NETR_MOUSE
NC score	0.423049 (rank : 23)	θ value	1.32909e-35 (rank : 11)
Query Neighborhood Hits	65	Target Neighborhood Hits	216	Shared Neighborhood Hits	33
SwissProt Accessions	O08762	Gene names	Prss12, Bssp3
Domain Architecture
Description	Neurotrypsin precursor (EC 3.4.21.-) (Motopsin) (Brain-specific serine protease 3) (BSSP-3).

MARCO_MOUSE
NC score	0.411170 (rank : 24)	θ value	8.10077e-17 (rank : 21)
Query Neighborhood Hits	65	Target Neighborhood Hits	242	Shared Neighborhood Hits	29
SwissProt Accessions	Q60754	Gene names	Marco
Domain Architecture
Description	Macrophage receptor MARCO (Macrophage receptor with collagenous structure).

LYOX_HUMAN
NC score	0.280600 (rank : 25)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	65	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	P28300, Q5FWF0	Gene names	LOX
Domain Architecture
Description	Protein-lysine 6-oxidase precursor (EC 1.4.3.13) (Lysyl oxidase).

LYOX_MOUSE
NC score	0.278459 (rank : 26)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	65	Target Neighborhood Hits	22	Shared Neighborhood Hits	6
SwissProt Accessions	P28301	Gene names	Lox, Rrg
Domain Architecture
Description	Protein-lysine 6-oxidase precursor (EC 1.4.3.13) (Lysyl oxidase) (RAS excision protein).

LOXL1_HUMAN
NC score	0.267108 (rank : 27)	θ value	θ > 10 (rank : 79)
Query Neighborhood Hits	65	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q08397, Q96BW7	Gene names	LOXL1, LOXL
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (LOL).

LOXL1_MOUSE
NC score	0.266159 (rank : 28)	θ value	θ > 10 (rank : 80)
Query Neighborhood Hits	65	Target Neighborhood Hits	58	Shared Neighborhood Hits	7
SwissProt Accessions	P97873, Q91ZY4, Q99KX3	Gene names	Loxl1, Lox2, Loxl
Domain Architecture
Description	Lysyl oxidase homolog 1 precursor (EC 1.4.3.-) (Lysyl oxidase-like protein 1) (Lysyl oxidase 2).

CUZD1_MOUSE
NC score	0.116962 (rank : 29)	θ value	θ > 10 (rank : 77)
Query Neighborhood Hits	65	Target Neighborhood Hits	91	Shared Neighborhood Hits	4
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

ENTK_MOUSE
NC score	0.116889 (rank : 30)	θ value	0.000121331 (rank : 25)
Query Neighborhood Hits	65	Target Neighborhood Hits	338	Shared Neighborhood Hits	28
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

CUZD1_HUMAN
NC score	0.112888 (rank : 31)	θ value	θ > 10 (rank : 76)
Query Neighborhood Hits	65	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CFAI_MOUSE
NC score	0.111972 (rank : 32)	θ value	0.163984 (rank : 29)
Query Neighborhood Hits	65	Target Neighborhood Hits	290	Shared Neighborhood Hits	28
SwissProt Accessions	Q61129, Q9WU07	Gene names	Cfi, If
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

CFAI_HUMAN
NC score	0.108825 (rank : 33)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	65	Target Neighborhood Hits	289	Shared Neighborhood Hits	29
SwissProt Accessions	P05156, O60442	Gene names	CFI, IF
Domain Architecture
Description	Complement factor I precursor (EC 3.4.21.45) (C3B/C4B inactivator) [Contains: Complement factor I heavy chain; Complement factor I light chain].

ENTK_HUMAN
NC score	0.103410 (rank : 34)	θ value	0.00228821 (rank : 26)
Query Neighborhood Hits	65	Target Neighborhood Hits	310	Shared Neighborhood Hits	30
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

TMPS3_HUMAN
NC score	0.081672 (rank : 35)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	65	Target Neighborhood Hits	245	Shared Neighborhood Hits	29
SwissProt Accessions	P57727, Q6ZMC3	Gene names	TMPRSS3, ECHOS1, TADG12
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-) (Serine protease TADG- 12) (Tumor-associated differentially-expressed gene 12 protein).

TMPS3_MOUSE
NC score	0.079026 (rank : 36)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	65	Target Neighborhood Hits	239	Shared Neighborhood Hits	29
SwissProt Accessions	Q8K1T0, Q8VDE0	Gene names	Tmprss3
Domain Architecture
Description	Transmembrane protease, serine 3 (EC 3.4.21.-).

TMPSD_MOUSE
NC score	0.076885 (rank : 37)	θ value	0.813845 (rank : 32)
Query Neighborhood Hits	65	Target Neighborhood Hits	334	Shared Neighborhood Hits	31
SwissProt Accessions	Q5U405, Q8CFE0, Q91VQ8	Gene names	Tmprss13, Msp
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

PCOC2_MOUSE
NC score	0.063634 (rank : 38)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	65	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

ZP2_HUMAN
NC score	0.063075 (rank : 39)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	65	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q05996	Gene names	ZP2, ZPA
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

ST14_MOUSE
NC score	0.062864 (rank : 40)	θ value	θ > 10 (rank : 100)
Query Neighborhood Hits	65	Target Neighborhood Hits	419	Shared Neighborhood Hits	13
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

PCOC2_HUMAN
NC score	0.062700 (rank : 41)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	65	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

ST14_HUMAN
NC score	0.061045 (rank : 42)	θ value	θ > 10 (rank : 99)
Query Neighborhood Hits	65	Target Neighborhood Hits	409	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

TMPS4_MOUSE
NC score	0.060593 (rank : 43)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	65	Target Neighborhood Hits	210	Shared Neighborhood Hits	23
SwissProt Accessions	Q8VCA5	Gene names	Tmprss4, Cap2
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (mCAP2).

TLL1_MOUSE
NC score	0.059921 (rank : 44)	θ value	θ > 10 (rank : 106)
Query Neighborhood Hits	65	Target Neighborhood Hits	237	Shared Neighborhood Hits	6
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TSG6_HUMAN
NC score	0.059809 (rank : 45)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	65	Target Neighborhood Hits	91	Shared Neighborhood Hits	5
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
NC score	0.059791 (rank : 46)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	65	Target Neighborhood Hits	91	Shared Neighborhood Hits	5
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TMPS5_MOUSE
NC score	0.059719 (rank : 47)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	65	Target Neighborhood Hits	185	Shared Neighborhood Hits	18
SwissProt Accessions	Q9ER04, Q9ER02, Q9ER03	Gene names	Tmprss5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

TLL1_HUMAN
NC score	0.058971 (rank : 48)	θ value	θ > 10 (rank : 105)
Query Neighborhood Hits	65	Target Neighborhood Hits	236	Shared Neighborhood Hits	6
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TMPS2_HUMAN
NC score	0.058686 (rank : 49)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	65	Target Neighborhood Hits	252	Shared Neighborhood Hits	21
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

CORIN_MOUSE
NC score	0.058230 (rank : 50)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	65	Target Neighborhood Hits	451	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

TLL2_MOUSE
NC score	0.058006 (rank : 51)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	65	Target Neighborhood Hits	240	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

ZP2_MOUSE
NC score	0.057638 (rank : 52)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	65	Target Neighborhood Hits	28	Shared Neighborhood Hits	3
SwissProt Accessions	P20239	Gene names	Zp2, Zp-2, Zpa
Domain Architecture
Description	Zona pellucida sperm-binding protein 2 precursor (Zona pellucida glycoprotein ZP2) (Zona pellucida protein A).

TLL2_HUMAN
NC score	0.057251 (rank : 53)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	65	Target Neighborhood Hits	241	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

CS1B_MOUSE
NC score	0.057244 (rank : 54)	θ value	θ > 10 (rank : 75)
Query Neighborhood Hits	65	Target Neighborhood Hits	361	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

MASP1_HUMAN
NC score	0.057179 (rank : 55)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	65	Target Neighborhood Hits	369	Shared Neighborhood Hits	13
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

TMPSD_HUMAN
NC score	0.057142 (rank : 56)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	65	Target Neighborhood Hits	333	Shared Neighborhood Hits	23
SwissProt Accessions	Q9BYE2, Q86YM4, Q96JY8, Q9BYE1	Gene names	TMPRSS13, MSP, TMPRSS11
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 13 (EC 3.4.21.-) (Mosaic serine protease) (Membrane-type mosaic serine protease).

PCOC1_MOUSE
NC score	0.056853 (rank : 57)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	65	Target Neighborhood Hits	100	Shared Neighborhood Hits	4
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

MASP1_MOUSE
NC score	0.056448 (rank : 58)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	65	Target Neighborhood Hits	364	Shared Neighborhood Hits	13
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

CS1A_MOUSE
NC score	0.056428 (rank : 59)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	65	Target Neighborhood Hits	360	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

C1S_HUMAN
NC score	0.056322 (rank : 60)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	65	Target Neighborhood Hits	359	Shared Neighborhood Hits	13
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

PCOC1_HUMAN
NC score	0.056014 (rank : 61)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	65	Target Neighborhood Hits	146	Shared Neighborhood Hits	5
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

ZP4_HUMAN
NC score	0.056013 (rank : 62)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	65	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q12836	Gene names	ZP4, ZPB
Domain Architecture
Description	Zona pellucida sperm-binding protein 4 precursor (Zona pellucida sperm-binding protein B).

MASP2_HUMAN
NC score	0.055570 (rank : 63)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	65	Target Neighborhood Hits	364	Shared Neighborhood Hits	13
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

BMP1_MOUSE
NC score	0.055147 (rank : 64)	θ value	θ > 10 (rank : 67)
Query Neighborhood Hits	65	Target Neighborhood Hits	236	Shared Neighborhood Hits	5
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_HUMAN
NC score	0.054873 (rank : 65)	θ value	θ > 10 (rank : 66)
Query Neighborhood Hits	65	Target Neighborhood Hits	233	Shared Neighborhood Hits	5
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TGBR3_HUMAN
NC score	0.054441 (rank : 66)	θ value	θ > 10 (rank : 103)
Query Neighborhood Hits	65	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q03167, Q5T2T4, Q5U731, Q9UGI2	Gene names	TGFBR3
Domain Architecture
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

TECTB_MOUSE
NC score	0.054154 (rank : 67)	θ value	θ > 10 (rank : 102)
Query Neighborhood Hits	65	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	O08524	Gene names	Tectb
Domain Architecture
Description	Beta-tectorin precursor.

NETO2_MOUSE
NC score	0.054125 (rank : 68)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	65	Target Neighborhood Hits	113	Shared Neighborhood Hits	7
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

TECTB_HUMAN
NC score	0.054123 (rank : 69)	θ value	θ > 10 (rank : 101)
Query Neighborhood Hits	65	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q96PL2	Gene names	TECTB
Domain Architecture
Description	Beta-tectorin precursor.

TMPS7_HUMAN
NC score	0.053992 (rank : 70)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	65	Target Neighborhood Hits	275	Shared Neighborhood Hits	13
SwissProt Accessions	Q7RTY8	Gene names	TMPRSS7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

C1R_HUMAN
NC score	0.053948 (rank : 71)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	65	Target Neighborhood Hits	364	Shared Neighborhood Hits	13
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

NETO2_HUMAN
NC score	0.053901 (rank : 72)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	65	Target Neighborhood Hits	109	Shared Neighborhood Hits	7
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

MFRP_MOUSE
NC score	0.053418 (rank : 73)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	65	Target Neighborhood Hits	166	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

C1RB_MOUSE
NC score	0.053321 (rank : 74)	θ value	θ > 10 (rank : 69)
Query Neighborhood Hits	65	Target Neighborhood Hits	380	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

LRP12_MOUSE
NC score	0.053213 (rank : 75)	θ value	θ > 10 (rank : 82)
Query Neighborhood Hits	65	Target Neighborhood Hits	180	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP12_HUMAN
NC score	0.053113 (rank : 76)	θ value	θ > 10 (rank : 81)
Query Neighborhood Hits	65	Target Neighborhood Hits	205	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

TGBR3_MOUSE
NC score	0.053027 (rank : 77)	θ value	θ > 10 (rank : 104)
Query Neighborhood Hits	65	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	O88393, Q6NS72	Gene names	Tgfbr3
Domain Architecture	No domain graphic available
Description	TGF-beta receptor type III precursor (TGFR-3) (Transforming growth factor beta receptor III) (Betaglycan).

MASP2_MOUSE
NC score	0.052893 (rank : 78)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	65	Target Neighborhood Hits	382	Shared Neighborhood Hits	13
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

TMPS5_HUMAN
NC score	0.052839 (rank : 79)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	65	Target Neighborhood Hits	181	Shared Neighborhood Hits	15
SwissProt Accessions	Q9H3S3	Gene names	TMPRSS5
Domain Architecture
Description	Transmembrane protease, serine 5 (EC 3.4.21.-) (Spinesin).

ZP3_MOUSE
NC score	0.052726 (rank : 80)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	65	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P10761	Gene names	Zp3, Zp-3, Zpc
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 precursor (Zona pellucida glycoprotein ZP3) (Sperm receptor) (Zona pellucida protein C).

MFRP_HUMAN
NC score	0.052553 (rank : 81)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	65	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

C1RA_MOUSE
NC score	0.052508 (rank : 82)	θ value	θ > 10 (rank : 68)
Query Neighborhood Hits	65	Target Neighborhood Hits	379	Shared Neighborhood Hits	14
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

NETO1_HUMAN
NC score	0.052193 (rank : 83)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	65	Target Neighborhood Hits	110	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

KREM1_MOUSE
NC score	0.051867 (rank : 84)	θ value	θ > 10 (rank : 78)
Query Neighborhood Hits	65	Target Neighborhood Hits	92	Shared Neighborhood Hits	6
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

NETO1_MOUSE
NC score	0.051669 (rank : 85)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	65	Target Neighborhood Hits	109	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

TMPS7_MOUSE
NC score	0.051470 (rank : 86)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	65	Target Neighborhood Hits	275	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BIK6	Gene names	Tmprss7
Domain Architecture	No domain graphic available
Description	Transmembrane protease, serine 7 precursor (EC 3.4.21.-).

TMPS4_HUMAN
NC score	0.050309 (rank : 87)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	65	Target Neighborhood Hits	203	Shared Neighborhood Hits	15
SwissProt Accessions	Q9NRS4, Q5XKQ6, Q6UX37, Q9NZA5	Gene names	TMPRSS4, TMPRSS3
Domain Architecture
Description	Transmembrane protease, serine 4 (EC 3.4.21.-) (Membrane-type serine protease 2) (MT-SP2).

TMPS2_MOUSE
NC score	0.049233 (rank : 88)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	65	Target Neighborhood Hits	243	Shared Neighborhood Hits	14
SwissProt Accessions	Q9JIQ8, Q9JKC4, Q9QY82	Gene names	Tmprss2
Domain Architecture
Description	Transmembrane protease, serine 2 (EC 3.4.21.-) (Epitheliasin) (Plasmic transmembrane protein X) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

SYNP2_MOUSE
NC score	0.036600 (rank : 89)	θ value	0.0113563 (rank : 27)
Query Neighborhood Hits	65	Target Neighborhood Hits	252	Shared Neighborhood Hits	7
SwissProt Accessions	Q91YE8, Q8C592	Gene names	Synpo2
Domain Architecture	No domain graphic available
Description	Synaptopodin-2 (Myopodin).

CETP_HUMAN
NC score	0.029323 (rank : 90)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	65	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	P11597, Q13987, Q13988	Gene names	CETP
Domain Architecture
Description	Cholesteryl ester transfer protein precursor (Lipid transfer protein I).

HSH2D_MOUSE
NC score	0.026346 (rank : 91)	θ value	0.365318 (rank : 30)
Query Neighborhood Hits	65	Target Neighborhood Hits	124	Shared Neighborhood Hits	2
SwissProt Accessions	Q6VYH9, Q52KL3	Gene names	Hsh2d, Alx
Domain Architecture	No domain graphic available
Description	Hematopoietic SH2 domain-containing protein (Hematopoietic SH2 protein) (Adaptor in lymphocytes of unknown function X).

IF4B_MOUSE
NC score	0.022343 (rank : 92)	θ value	1.81305 (rank : 36)
Query Neighborhood Hits	65	Target Neighborhood Hits	368	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BGD9, Q3TD64	Gene names	Eif4b
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4B (eIF-4B).

AMPD3_MOUSE
NC score	0.021827 (rank : 93)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	65	Target Neighborhood Hits	34	Shared Neighborhood Hits	5
SwissProt Accessions	O08739, O88692	Gene names	Ampd3
Domain Architecture
Description	AMP deaminase 3 (EC 3.5.4.6) (AMP deaminase isoform E) (AMP deaminase H-type) (Heart-type AMPD).

DMRTD_HUMAN
NC score	0.021017 (rank : 94)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	65	Target Neighborhood Hits	216	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IXT2, Q8N6Q2, Q96M39, Q96SD4	Gene names	DMRTC2
Domain Architecture	No domain graphic available
Description	Doublesex- and mab-3-related transcription factor C2.

AMPD3_HUMAN
NC score	0.018481 (rank : 95)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	65	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q01432	Gene names	AMPD3
Domain Architecture
Description	AMP deaminase 3 (EC 3.5.4.6) (AMP deaminase isoform E) (Erythrocyte AMP deaminase).

SON_MOUSE
NC score	0.017595 (rank : 96)	θ value	3.0926 (rank : 45)
Query Neighborhood Hits	65	Target Neighborhood Hits	957	Shared Neighborhood Hits	14
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

CENPC_HUMAN
NC score	0.015274 (rank : 97)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	65	Target Neighborhood Hits	147	Shared Neighborhood Hits	2
SwissProt Accessions	Q03188, Q9P0M5	Gene names	CENPC1, CENPC, ICEN7
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C) (Interphase centromere complex protein 7).

RGS3_MOUSE
NC score	0.013648 (rank : 98)	θ value	0.0961366 (rank : 28)
Query Neighborhood Hits	65	Target Neighborhood Hits	1621	Shared Neighborhood Hits	17
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

NUPL2_MOUSE
NC score	0.013646 (rank : 99)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	65	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CIC2, Q8BJX3, Q8BVP7, Q924S0	Gene names	Nupl2
Domain Architecture	No domain graphic available
Description	Nucleoporin-like 2 (NLP-1).

SOS1_HUMAN
NC score	0.011596 (rank : 100)	θ value	1.38821 (rank : 34)
Query Neighborhood Hits	65	Target Neighborhood Hits	274	Shared Neighborhood Hits	7
SwissProt Accessions	Q07889	Gene names	SOS1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1).

MLL3_MOUSE
NC score	0.010637 (rank : 101)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	65	Target Neighborhood Hits	1399	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL3_HUMAN
NC score	0.010636 (rank : 102)	θ value	2.36792 (rank : 41)
Query Neighborhood Hits	65	Target Neighborhood Hits	1644	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

EFHD1_MOUSE
NC score	0.010519 (rank : 103)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	65	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D4J1, Q543U4	Gene names	Efhd1, Sws2
Domain Architecture
Description	EF-hand domain-containing protein 1 (Swiprosin-2).

ADA12_HUMAN
NC score	0.009652 (rank : 104)	θ value	1.81305 (rank : 35)
Query Neighborhood Hits	65	Target Neighborhood Hits	224	Shared Neighborhood Hits	5
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

GRN_HUMAN
NC score	0.009338 (rank : 105)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	65	Target Neighborhood Hits	268	Shared Neighborhood Hits	4
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

MKL1_MOUSE
NC score	0.009120 (rank : 106)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	65	Target Neighborhood Hits	667	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

ADA12_MOUSE
NC score	0.008371 (rank : 107)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	65	Target Neighborhood Hits	474	Shared Neighborhood Hits	8
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

PRRT3_HUMAN
NC score	0.008272 (rank : 108)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	65	Target Neighborhood Hits	998	Shared Neighborhood Hits	12
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

LCP2_HUMAN
NC score	0.007420 (rank : 109)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	65	Target Neighborhood Hits	531	Shared Neighborhood Hits	9
SwissProt Accessions	Q13094	Gene names	LCP2
Domain Architecture
Description	Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76).

SFR14_MOUSE
NC score	0.006906 (rank : 110)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	65	Target Neighborhood Hits	238	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CH09, Q6PG19, Q80UY8, Q8BY32, Q8CFM0	Gene names	Sfrs14
Domain Architecture	No domain graphic available
Description	Putative splicing factor, arginine/serine-rich 14 (Arginine/serine- rich-splicing factor 14).

PAX2_MOUSE
NC score	0.006855 (rank : 111)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	65	Target Neighborhood Hits	86	Shared Neighborhood Hits	3
SwissProt Accessions	P32114	Gene names	Pax2, Pax-2
Domain Architecture
Description	Paired box protein Pax-2.

PLXB1_HUMAN
NC score	0.005402 (rank : 112)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	65	Target Neighborhood Hits	360	Shared Neighborhood Hits	5
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

CSPG2_HUMAN
NC score	0.004296 (rank : 113)	θ value	2.36792 (rank : 40)
Query Neighborhood Hits	65	Target Neighborhood Hits	681	Shared Neighborhood Hits	4
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

FGD5_HUMAN
NC score	0.003315 (rank : 114)	θ value	8.99809 (rank : 61)
Query Neighborhood Hits	65	Target Neighborhood Hits	235	Shared Neighborhood Hits	3
SwissProt Accessions	Q6ZNL6, Q6MZY1, Q7Z303, Q8IYP3, Q8N861, Q8N8G4	Gene names	FGD5, ZFYVE23
Domain Architecture	No domain graphic available
Description	FYVE, RhoGEF and PH domain-containing protein 5 (Zinc finger FYVE domain-containing protein 23).

LTBP2_HUMAN
NC score	0.003109 (rank : 115)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	65	Target Neighborhood Hits	552	Shared Neighborhood Hits	9
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

HXC10_HUMAN
NC score	0.001819 (rank : 116)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	65	Target Neighborhood Hits	417	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYD6, O15219, O15220, Q9BVD5	Gene names	HOXC10
Domain Architecture
Description	Homeobox protein Hox-C10.

BICD1_HUMAN
NC score	0.000626 (rank : 117)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	65	Target Neighborhood Hits	844	Shared Neighborhood Hits	2
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

SPEG_MOUSE
NC score	-0.002405 (rank : 118)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	65	Target Neighborhood Hits	1959	Shared Neighborhood Hits	13
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZN366_HUMAN
NC score	-0.003206 (rank : 119)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	65	Target Neighborhood Hits	732	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N895, Q7RTV4	Gene names	ZNF366
Domain Architecture	No domain graphic available
Description	Zinc finger protein 366.

MARK4_HUMAN
NC score	-0.003366 (rank : 120)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	65	Target Neighborhood Hits	886	Shared Neighborhood Hits	5
SwissProt Accessions	Q96L34, Q8NG37, Q96JG7, Q96SQ2, Q9BYD8	Gene names	MARK4, KIAA1860, MARKL1
Domain Architecture
Description	MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase-like 1).

ZN606_HUMAN
NC score	-0.003670 (rank : 121)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	65	Target Neighborhood Hits	749	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXB4, Q8NE04, Q96JH5	Gene names	ZNF606, KIAA1852, ZNF328
Domain Architecture
Description	Zinc finger protein 606 (Zinc finger protein 328).