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Network neighborhood for query Sequence : SYV_MOUSE

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SYV_MOUSE
SwissProt Accessions	Q9Z1Q9, Q9QUN2	Gene names	Vars, Bat6, G7a, Vars2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SYV_HUMAN
θ value	0 (rank : 1)	NC score	0.994258 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	41	Shared Neighborhood Hits	24
SwissProt Accessions	P26640, Q5JQ90, Q96E77, Q9UQM2	Gene names	VARS, G7A, VARS2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

SYV_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z1Q9, Q9QUN2	Gene names	Vars, Bat6, G7a, Vars2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

SYIM_MOUSE
θ value	1.72781e-51 (rank : 3)	NC score	0.762480 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BIJ6, Q3TKT8, Q8BIJ0, Q8BIP3	Gene names	Iars2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

SYIM_HUMAN
θ value	6.7944e-48 (rank : 4)	NC score	0.756982 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NSE4, Q6PI85, Q7L439, Q86WU9, Q96D91	Gene names	IARS2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

SYIC_HUMAN
θ value	2.05049e-36 (rank : 5)	NC score	0.694356 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	42	Shared Neighborhood Hits	14
SwissProt Accessions	P41252, Q5TCD0, Q9H588	Gene names	IARS
Domain Architecture
Description	Isoleucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS) (IRS).

SYIC_MOUSE
θ value	2.50655e-34 (rank : 6)	NC score	0.692172 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BU30	Gene names	Iars
Domain Architecture
Description	Isoleucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS) (IRS).

EF1G_HUMAN
θ value	5.59698e-26 (rank : 7)	NC score	0.552033 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	P26641, Q6PJ62, Q6PK31, Q96CU2, Q9P196	Gene names	EEF1G, EF1G
Domain Architecture
Description	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).

EF1G_MOUSE
θ value	1.24688e-25 (rank : 8)	NC score	0.550959 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D8N0, Q920C5, Q9CRT5, Q9CSU3, Q9D004	Gene names	Eef1g
Domain Architecture
Description	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).

SYLM_HUMAN
θ value	1.86753e-13 (rank : 9)	NC score	0.485174 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	Q15031	Gene names	LARS2, KIAA0028
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYLM_MOUSE
θ value	3.52202e-12 (rank : 10)	NC score	0.480554 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VDC0	Gene names	Lars2
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYMM_MOUSE
θ value	9.29e-05 (rank : 11)	NC score	0.241417 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q499X9, Q3T9W7, Q8BWR9, Q8BXY1	Gene names	Mars2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

SYMM_HUMAN
θ value	0.00175202 (rank : 12)	NC score	0.219756 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	Q96GW9, Q76E79, Q8IW62, Q8N7N4	Gene names	MARS2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

SYLC_MOUSE
θ value	0.00390308 (rank : 13)	NC score	0.229778 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMJ2, Q8BKW9	Gene names	Lars
Domain Architecture
Description	Leucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYLC_HUMAN
θ value	0.0193708 (rank : 14)	NC score	0.236033 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P2J5, Q9NSE1	Gene names	LARS, KIAA1352
Domain Architecture
Description	Leucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYEP_MOUSE
θ value	0.0252991 (rank : 15)	NC score	0.079501 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CGC7	Gene names	Eprs, Qprs
Domain Architecture	No domain graphic available
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

SYM_MOUSE
θ value	0.365318 (rank : 16)	NC score	0.106060 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q68FL6	Gene names	Mars
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

SYM_HUMAN
θ value	0.813845 (rank : 17)	NC score	0.151583 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	43	Shared Neighborhood Hits	17
SwissProt Accessions	P56192, Q14895, Q53H14, Q96A15, Q96BZ0, Q9NSE0	Gene names	MARS
Domain Architecture
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

DESP_HUMAN
θ value	1.06291 (rank : 18)	NC score	0.008348 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	1470	Shared Neighborhood Hits	9
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

GSTT2_HUMAN
θ value	1.06291 (rank : 19)	NC score	0.066750 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	P30712, O60665, Q9HD76	Gene names	GSTT2
Domain Architecture
Description	Glutathione S-transferase theta-2 (EC 2.5.1.18) (GST class-theta-2).

IBP5_MOUSE
θ value	1.38821 (rank : 20)	NC score	0.018224 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

TGON2_MOUSE
θ value	1.38821 (rank : 21)	NC score	0.023716 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	277	Shared Neighborhood Hits	2
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

ACM3_MOUSE
θ value	2.36792 (rank : 22)	NC score	0.002276 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	932	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERZ3, Q64055	Gene names	Chrm3, Chrm-3
Domain Architecture
Description	Muscarinic acetylcholine receptor M3 (Mm3 mAChR).

MCA3_MOUSE
θ value	3.0926 (rank : 23)	NC score	0.135944 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D1M4	Gene names	Eef1e1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation elongation factor 1 epsilon-1 (Multisynthetase complex auxiliary component p18) (Elongation factor p18).

RIMB1_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.007533 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	1376	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

SYEP_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.049778 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	70	Shared Neighborhood Hits	7
SwissProt Accessions	P07814	Gene names	EPRS, GLNS, PARS, QPRS
Domain Architecture
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

ZN232_HUMAN
θ value	3.0926 (rank : 26)	NC score	-0.000673 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	754	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UNY5	Gene names	ZNF232, ZSCAN11
Domain Architecture
Description	Zinc finger protein 232 (Zinc finger and SCAN domain-containing protein 11).

CNTP1_MOUSE
θ value	4.03905 (rank : 27)	NC score	0.010835 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	183	Shared Neighborhood Hits	3
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

KCNH1_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.015905 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

KCNH1_MOUSE
θ value	4.03905 (rank : 29)	NC score	0.015914 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

MISS_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.014540 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	444	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

OPTN_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.008407 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	827	Shared Neighborhood Hits	7
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

ZAR1_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.019912 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

KS6B1_HUMAN
θ value	5.27518 (rank : 33)	NC score	0.002179 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	850	Shared Neighborhood Hits	5
SwissProt Accessions	P23443	Gene names	RPS6KB1
Domain Architecture
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K) (p70-alpha).

KS6B1_MOUSE
θ value	5.27518 (rank : 34)	NC score	0.002180 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	849	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BSK8, Q8CHX0	Gene names	Rps6kb1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K).

TRPS1_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.012849 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	609	Shared Neighborhood Hits	3
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

UBP14_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.011711 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

ANKR6_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.002622 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	439	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

KS6B2_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.001636 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	858	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBS0, O94809, Q9UEC1	Gene names	RPS6KB2, STK14B
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14 beta).

NAF1_MOUSE
θ value	6.88961 (rank : 39)	NC score	0.006677 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	852	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

PGTA_MOUSE
θ value	6.88961 (rank : 40)	NC score	0.010607 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	150	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHK4, Q9JLX2	Gene names	Rabggta
Domain Architecture
Description	Geranylgeranyl transferase type-2 alpha subunit (EC 2.5.1.60) (Geranylgeranyl transferase type II alpha subunit) (Rab geranylgeranyltransferase alpha subunit) (Rab geranyl- geranyltransferase alpha subunit) (Rab GG transferase alpha) (Rab GGTase alpha).

AKAP2_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.009355 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	385	Shared Neighborhood Hits	5
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

CN092_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.007767 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	143	Shared Neighborhood Hits	2
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

CNTP1_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.009068 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

DPOD3_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.011501 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q15054	Gene names	POLD3, KIAA0039
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

DYH9_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.006159 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	291	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

MY18A_HUMAN
θ value	8.99809 (rank : 46)	NC score	0.001171 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	1929	Shared Neighborhood Hits	10
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TRPS1_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.011417 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	539	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHF7, Q9NWE1, Q9UHH6	Gene names	TRPS1
Domain Architecture
Description	Zinc finger transcription factor Trps1 (Zinc finger protein GC79) (Tricho-rhino-phalangeal syndrome type I protein).

MCA3_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.083380 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	O43324, Q5THS2	Gene names	EEF1E1
Domain Architecture
Description	Eukaryotic translation elongation factor 1 epsilon-1 (Multisynthetase complex auxiliary component p18) (Elongation factor p18).

Hits sorted by NC score

SYV_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z1Q9, Q9QUN2	Gene names	Vars, Bat6, G7a, Vars2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

SYV_HUMAN
NC score	0.994258 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	41	Shared Neighborhood Hits	24
SwissProt Accessions	P26640, Q5JQ90, Q96E77, Q9UQM2	Gene names	VARS, G7A, VARS2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

SYIM_MOUSE
NC score	0.762480 (rank : 3)	θ value	1.72781e-51 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BIJ6, Q3TKT8, Q8BIJ0, Q8BIP3	Gene names	Iars2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

SYIM_HUMAN
NC score	0.756982 (rank : 4)	θ value	6.7944e-48 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NSE4, Q6PI85, Q7L439, Q86WU9, Q96D91	Gene names	IARS2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

SYIC_HUMAN
NC score	0.694356 (rank : 5)	θ value	2.05049e-36 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	42	Shared Neighborhood Hits	14
SwissProt Accessions	P41252, Q5TCD0, Q9H588	Gene names	IARS
Domain Architecture
Description	Isoleucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS) (IRS).

SYIC_MOUSE
NC score	0.692172 (rank : 6)	θ value	2.50655e-34 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BU30	Gene names	Iars
Domain Architecture
Description	Isoleucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS) (IRS).

EF1G_HUMAN
NC score	0.552033 (rank : 7)	θ value	5.59698e-26 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	30	Shared Neighborhood Hits	10
SwissProt Accessions	P26641, Q6PJ62, Q6PK31, Q96CU2, Q9P196	Gene names	EEF1G, EF1G
Domain Architecture
Description	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).

EF1G_MOUSE
NC score	0.550959 (rank : 8)	θ value	1.24688e-25 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D8N0, Q920C5, Q9CRT5, Q9CSU3, Q9D004	Gene names	Eef1g
Domain Architecture
Description	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).

SYLM_HUMAN
NC score	0.485174 (rank : 9)	θ value	1.86753e-13 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	Q15031	Gene names	LARS2, KIAA0028
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYLM_MOUSE
NC score	0.480554 (rank : 10)	θ value	3.52202e-12 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VDC0	Gene names	Lars2
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYMM_MOUSE
NC score	0.241417 (rank : 11)	θ value	9.29e-05 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	Q499X9, Q3T9W7, Q8BWR9, Q8BXY1	Gene names	Mars2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

SYLC_HUMAN
NC score	0.236033 (rank : 12)	θ value	0.0193708 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P2J5, Q9NSE1	Gene names	LARS, KIAA1352
Domain Architecture
Description	Leucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYLC_MOUSE
NC score	0.229778 (rank : 13)	θ value	0.00390308 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMJ2, Q8BKW9	Gene names	Lars
Domain Architecture
Description	Leucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYMM_HUMAN
NC score	0.219756 (rank : 14)	θ value	0.00175202 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	27	Shared Neighborhood Hits	14
SwissProt Accessions	Q96GW9, Q76E79, Q8IW62, Q8N7N4	Gene names	MARS2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

SYM_HUMAN
NC score	0.151583 (rank : 15)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	43	Shared Neighborhood Hits	17
SwissProt Accessions	P56192, Q14895, Q53H14, Q96A15, Q96BZ0, Q9NSE0	Gene names	MARS
Domain Architecture
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

MCA3_MOUSE
NC score	0.135944 (rank : 16)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	Q9D1M4	Gene names	Eef1e1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation elongation factor 1 epsilon-1 (Multisynthetase complex auxiliary component p18) (Elongation factor p18).

SYM_MOUSE
NC score	0.106060 (rank : 17)	θ value	0.365318 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	Q68FL6	Gene names	Mars
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

MCA3_HUMAN
NC score	0.083380 (rank : 18)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	14	Shared Neighborhood Hits	7
SwissProt Accessions	O43324, Q5THS2	Gene names	EEF1E1
Domain Architecture
Description	Eukaryotic translation elongation factor 1 epsilon-1 (Multisynthetase complex auxiliary component p18) (Elongation factor p18).

SYEP_MOUSE
NC score	0.079501 (rank : 19)	θ value	0.0252991 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CGC7	Gene names	Eprs, Qprs
Domain Architecture	No domain graphic available
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

GSTT2_HUMAN
NC score	0.066750 (rank : 20)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	P30712, O60665, Q9HD76	Gene names	GSTT2
Domain Architecture
Description	Glutathione S-transferase theta-2 (EC 2.5.1.18) (GST class-theta-2).

SYEP_HUMAN
NC score	0.049778 (rank : 21)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	70	Shared Neighborhood Hits	7
SwissProt Accessions	P07814	Gene names	EPRS, GLNS, PARS, QPRS
Domain Architecture
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

TGON2_MOUSE
NC score	0.023716 (rank : 22)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	277	Shared Neighborhood Hits	2
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

ZAR1_HUMAN
NC score	0.019912 (rank : 23)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q86SH2	Gene names	ZAR1
Domain Architecture	No domain graphic available
Description	Zygote arrest 1 (Oocyte-specific maternal effect factor).

IBP5_MOUSE
NC score	0.018224 (rank : 24)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q07079	Gene names	Igfbp5, Igfbp-5
Domain Architecture
Description	Insulin-like growth factor-binding protein 5 precursor (IGFBP-5) (IBP- 5) (IGF-binding protein 5).

KCNH1_MOUSE
NC score	0.015914 (rank : 25)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	94	Shared Neighborhood Hits	4
SwissProt Accessions	Q60603	Gene names	Kcnh1, Eag
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (EAG1) (m-eag).

KCNH1_HUMAN
NC score	0.015905 (rank : 26)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	O95259, O76035	Gene names	KCNH1, EAG, EAG1
Domain Architecture
Description	Potassium voltage-gated channel subfamily H member 1 (Voltage-gated potassium channel subunit Kv10.1) (Ether-a-go-go potassium channel 1) (hEAG1) (h-eag).

MISS_MOUSE
NC score	0.014540 (rank : 27)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	444	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D7G9, Q7M749	Gene names	Mapk1ip1, Miss
Domain Architecture	No domain graphic available
Description	MAPK-interacting and spindle-stabilizing protein (Mitogen-activated protein kinase 1-interacting protein 1).

TRPS1_MOUSE
NC score	0.012849 (rank : 28)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	609	Shared Neighborhood Hits	3
SwissProt Accessions	Q925H1	Gene names	Trps1
Domain Architecture
Description	Zinc finger transcription factor Trps1.

UBP14_HUMAN
NC score	0.011711 (rank : 29)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	89	Shared Neighborhood Hits	2
SwissProt Accessions	P54578	Gene names	USP14, TGT
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.1.2.15) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14) (Deubiquitinating enzyme 14).

DPOD3_HUMAN
NC score	0.011501 (rank : 30)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q15054	Gene names	POLD3, KIAA0039
Domain Architecture	No domain graphic available
Description	DNA polymerase subunit delta 3 (DNA polymerase subunit delta p66).

TRPS1_HUMAN
NC score	0.011417 (rank : 31)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	539	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHF7, Q9NWE1, Q9UHH6	Gene names	TRPS1
Domain Architecture
Description	Zinc finger transcription factor Trps1 (Zinc finger protein GC79) (Tricho-rhino-phalangeal syndrome type I protein).

CNTP1_MOUSE
NC score	0.010835 (rank : 32)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	183	Shared Neighborhood Hits	3
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

PGTA_MOUSE
NC score	0.010607 (rank : 33)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	150	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JHK4, Q9JLX2	Gene names	Rabggta
Domain Architecture
Description	Geranylgeranyl transferase type-2 alpha subunit (EC 2.5.1.60) (Geranylgeranyl transferase type II alpha subunit) (Rab geranylgeranyltransferase alpha subunit) (Rab geranyl- geranyltransferase alpha subunit) (Rab GG transferase alpha) (Rab GGTase alpha).

AKAP2_MOUSE
NC score	0.009355 (rank : 34)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	385	Shared Neighborhood Hits	5
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

CNTP1_HUMAN
NC score	0.009068 (rank : 35)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	196	Shared Neighborhood Hits	4
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

OPTN_HUMAN
NC score	0.008407 (rank : 36)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	827	Shared Neighborhood Hits	7
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

DESP_HUMAN
NC score	0.008348 (rank : 37)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	1470	Shared Neighborhood Hits	9
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

CN092_HUMAN
NC score	0.007767 (rank : 38)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	143	Shared Neighborhood Hits	2
SwissProt Accessions	O94842	Gene names	C14orf92, KIAA0737
Domain Architecture
Description	Epidermal Langerhans cell protein LCP1.

RIMB1_MOUSE
NC score	0.007533 (rank : 39)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	1376	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

NAF1_MOUSE
NC score	0.006677 (rank : 40)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	852	Shared Neighborhood Hits	6
SwissProt Accessions	Q9WUU8, Q922A9, Q922F7, Q9EPP8, Q9R0X3	Gene names	Tnip1, Abin, Naf1
Domain Architecture
Description	Nef-associated factor 1 (Naf1) (TNFAIP3-interacting protein 1) (A20- binding inhibitor of NF-kappa-B activation) (ABIN) (Virion-associated nuclear shuttling protein) (VAN) (mVAN).

DYH9_HUMAN
NC score	0.006159 (rank : 41)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	291	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NYC9, O95494, Q9NQ28	Gene names	DNAH9, DNAH17L, DNAL1
Domain Architecture
Description	Ciliary dynein heavy chain 9 (Axonemal beta dynein heavy chain 9).

ANKR6_HUMAN
NC score	0.002622 (rank : 42)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	439	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ACM3_MOUSE
NC score	0.002276 (rank : 43)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	932	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ERZ3, Q64055	Gene names	Chrm3, Chrm-3
Domain Architecture
Description	Muscarinic acetylcholine receptor M3 (Mm3 mAChR).

KS6B1_MOUSE
NC score	0.002180 (rank : 44)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	849	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BSK8, Q8CHX0	Gene names	Rps6kb1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K).

KS6B1_HUMAN
NC score	0.002179 (rank : 45)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	850	Shared Neighborhood Hits	5
SwissProt Accessions	P23443	Gene names	RPS6KB1
Domain Architecture
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K) (p70-alpha).

KS6B2_HUMAN
NC score	0.001636 (rank : 46)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	858	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBS0, O94809, Q9UEC1	Gene names	RPS6KB2, STK14B
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14 beta).

MY18A_HUMAN
NC score	0.001171 (rank : 47)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	1929	Shared Neighborhood Hits	10
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

ZN232_HUMAN
NC score	-0.000673 (rank : 48)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	754	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UNY5	Gene names	ZNF232, ZSCAN11
Domain Architecture
Description	Zinc finger protein 232 (Zinc finger and SCAN domain-containing protein 11).