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Network neighborhood for query Sequence : SYIC_HUMAN

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SYIC_HUMAN
SwissProt Accessions	P41252, Q5TCD0, Q9H588	Gene names	IARS
Domain Architecture
Description	Isoleucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS) (IRS).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SYIC_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	P41252, Q5TCD0, Q9H588	Gene names	IARS
Domain Architecture
Description	Isoleucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS) (IRS).

SYIC_MOUSE
θ value	0 (rank : 2)	NC score	0.993723 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BU30	Gene names	Iars
Domain Architecture
Description	Isoleucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS) (IRS).

SYIM_MOUSE
θ value	1.14825e-79 (rank : 3)	NC score	0.849477 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BIJ6, Q3TKT8, Q8BIJ0, Q8BIP3	Gene names	Iars2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

SYIM_HUMAN
θ value	5.8972e-76 (rank : 4)	NC score	0.847861 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NSE4, Q6PI85, Q7L439, Q86WU9, Q96D91	Gene names	IARS2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

SYV_MOUSE
θ value	2.05049e-36 (rank : 5)	NC score	0.694356 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z1Q9, Q9QUN2	Gene names	Vars, Bat6, G7a, Vars2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

SYV_HUMAN
θ value	1.01765e-35 (rank : 6)	NC score	0.689573 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	P26640, Q5JQ90, Q96E77, Q9UQM2	Gene names	VARS, G7A, VARS2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

SYLM_MOUSE
θ value	1.47974e-10 (rank : 7)	NC score	0.466458 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VDC0	Gene names	Lars2
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYLM_HUMAN
θ value	1.9326e-10 (rank : 8)	NC score	0.459575 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	Q15031	Gene names	LARS2, KIAA0028
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYLC_HUMAN
θ value	0.00665767 (rank : 9)	NC score	0.242973 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P2J5, Q9NSE1	Gene names	LARS, KIAA1352
Domain Architecture
Description	Leucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

MYH3_HUMAN
θ value	0.0961366 (rank : 10)	NC score	0.040814 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	1660	Shared Neighborhood Hits	19
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH13_HUMAN
θ value	0.21417 (rank : 11)	NC score	0.042445 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	1504	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

EVPL_MOUSE
θ value	0.365318 (rank : 12)	NC score	0.039165 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	952	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

GCC2_HUMAN
θ value	0.365318 (rank : 13)	NC score	0.038370 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	1558	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

MYH8_HUMAN
θ value	0.365318 (rank : 14)	NC score	0.039922 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	1610	Shared Neighborhood Hits	19
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

RBP24_HUMAN
θ value	0.365318 (rank : 15)	NC score	0.038427 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	1559	Shared Neighborhood Hits	19
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

SDCG8_HUMAN
θ value	0.365318 (rank : 16)	NC score	0.033626 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	1002	Shared Neighborhood Hits	18
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

SYLC_MOUSE
θ value	0.365318 (rank : 17)	NC score	0.217700 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMJ2, Q8BKW9	Gene names	Lars
Domain Architecture
Description	Leucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

MYH4_MOUSE
θ value	0.47712 (rank : 18)	NC score	0.040498 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	1476	Shared Neighborhood Hits	19
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH8_MOUSE
θ value	0.47712 (rank : 19)	NC score	0.038734 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	1600	Shared Neighborhood Hits	19
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

SYMM_MOUSE
θ value	0.62314 (rank : 20)	NC score	0.141585 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q499X9, Q3T9W7, Q8BWR9, Q8BXY1	Gene names	Mars2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

MYH2_HUMAN
θ value	0.813845 (rank : 21)	NC score	0.038916 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	1491	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH1_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.038506 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	1478	Shared Neighborhood Hits	18
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

ZBT40_HUMAN
θ value	1.38821 (rank : 23)	NC score	0.001103 (rank : 44)
Query Neighborhood Hits	42	Target Neighborhood Hits	949	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

CS1B_MOUSE
θ value	1.81305 (rank : 24)	NC score	0.007570 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	361	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

EVPL_HUMAN
θ value	1.81305 (rank : 25)	NC score	0.037148 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	895	Shared Neighborhood Hits	19
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

MYH4_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.038687 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	1377	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

CHD8_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.008832 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	235	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

RFWD2_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.013675 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	518	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
θ value	3.0926 (rank : 29)	NC score	0.013670 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	535	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

MYH7_HUMAN
θ value	4.03905 (rank : 30)	NC score	0.036634 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	1559	Shared Neighborhood Hits	18
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

SAMD4_MOUSE
θ value	4.03905 (rank : 31)	NC score	0.024140 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CBY1	Gene names	Samd4
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

SYMM_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.118170 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	27	Shared Neighborhood Hits	13
SwissProt Accessions	Q96GW9, Q76E79, Q8IW62, Q8N7N4	Gene names	MARS2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

SYM_HUMAN
θ value	4.03905 (rank : 33)	NC score	0.079959 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	43	Shared Neighborhood Hits	11
SwissProt Accessions	P56192, Q14895, Q53H14, Q96A15, Q96BZ0, Q9NSE0	Gene names	MARS
Domain Architecture
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

CS1A_MOUSE
θ value	5.27518 (rank : 34)	NC score	0.006203 (rank : 43)
Query Neighborhood Hits	42	Target Neighborhood Hits	360	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

GCC2_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.032230 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	1619	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

IL21R_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.014980 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBE5, Q96HZ1, Q9HB91	Gene names	IL21R, NILR
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor).

K0773_HUMAN
θ value	5.27518 (rank : 37)	NC score	0.016211 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q86XD5, Q7L0D6, Q86T97	Gene names	KIAA0773
Domain Architecture	No domain graphic available
Description	Uncharacterized protein KIAA0773.

HEAT1_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.016726 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H583, Q5T3Q8, Q9NW23	Gene names	HEATR1, BAP28
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 1 (Protein BAP28).

MY18A_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.027098 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	1929	Shared Neighborhood Hits	20
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

S3TC2_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.010953 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TF17, Q9H8I5	Gene names	SH3TC2, KIAA1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

MYH6_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.036583 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	1426	Shared Neighborhood Hits	18
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

SAMD4_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.020053 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPU9	Gene names	SAMD4, KIAA1053
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

EF1G_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.118829 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	P26641, Q6PJ62, Q6PK31, Q96CU2, Q9P196	Gene names	EEF1G, EF1G
Domain Architecture
Description	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).

EF1G_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.118360 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D8N0, Q920C5, Q9CRT5, Q9CSU3, Q9D004	Gene names	Eef1g
Domain Architecture
Description	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).

Hits sorted by NC score

SYIC_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	42	Target Neighborhood Hits	42	Shared Neighborhood Hits	42
SwissProt Accessions	P41252, Q5TCD0, Q9H588	Gene names	IARS
Domain Architecture
Description	Isoleucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS) (IRS).

SYIC_MOUSE
NC score	0.993723 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	42	Target Neighborhood Hits	30	Shared Neighborhood Hits	22
SwissProt Accessions	Q8BU30	Gene names	Iars
Domain Architecture
Description	Isoleucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS) (IRS).

SYIM_MOUSE
NC score	0.849477 (rank : 3)	θ value	1.14825e-79 (rank : 3)
Query Neighborhood Hits	42	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BIJ6, Q3TKT8, Q8BIJ0, Q8BIP3	Gene names	Iars2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

SYIM_HUMAN
NC score	0.847861 (rank : 4)	θ value	5.8972e-76 (rank : 4)
Query Neighborhood Hits	42	Target Neighborhood Hits	20	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NSE4, Q6PI85, Q7L439, Q86WU9, Q96D91	Gene names	IARS2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

SYV_MOUSE
NC score	0.694356 (rank : 5)	θ value	2.05049e-36 (rank : 5)
Query Neighborhood Hits	42	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Z1Q9, Q9QUN2	Gene names	Vars, Bat6, G7a, Vars2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

SYV_HUMAN
NC score	0.689573 (rank : 6)	θ value	1.01765e-35 (rank : 6)
Query Neighborhood Hits	42	Target Neighborhood Hits	41	Shared Neighborhood Hits	13
SwissProt Accessions	P26640, Q5JQ90, Q96E77, Q9UQM2	Gene names	VARS, G7A, VARS2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

SYLM_MOUSE
NC score	0.466458 (rank : 7)	θ value	1.47974e-10 (rank : 7)
Query Neighborhood Hits	42	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VDC0	Gene names	Lars2
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYLM_HUMAN
NC score	0.459575 (rank : 8)	θ value	1.9326e-10 (rank : 8)
Query Neighborhood Hits	42	Target Neighborhood Hits	24	Shared Neighborhood Hits	13
SwissProt Accessions	Q15031	Gene names	LARS2, KIAA0028
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYLC_HUMAN
NC score	0.242973 (rank : 9)	θ value	0.00665767 (rank : 9)
Query Neighborhood Hits	42	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q9P2J5, Q9NSE1	Gene names	LARS, KIAA1352
Domain Architecture
Description	Leucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYLC_MOUSE
NC score	0.217700 (rank : 10)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	42	Target Neighborhood Hits	25	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BMJ2, Q8BKW9	Gene names	Lars
Domain Architecture
Description	Leucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYMM_MOUSE
NC score	0.141585 (rank : 11)	θ value	0.62314 (rank : 20)
Query Neighborhood Hits	42	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q499X9, Q3T9W7, Q8BWR9, Q8BXY1	Gene names	Mars2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

EF1G_HUMAN
NC score	0.118829 (rank : 12)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	42	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	P26641, Q6PJ62, Q6PK31, Q96CU2, Q9P196	Gene names	EEF1G, EF1G
Domain Architecture
Description	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).

EF1G_MOUSE
NC score	0.118360 (rank : 13)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	42	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D8N0, Q920C5, Q9CRT5, Q9CSU3, Q9D004	Gene names	Eef1g
Domain Architecture
Description	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).

SYMM_HUMAN
NC score	0.118170 (rank : 14)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	42	Target Neighborhood Hits	27	Shared Neighborhood Hits	13
SwissProt Accessions	Q96GW9, Q76E79, Q8IW62, Q8N7N4	Gene names	MARS2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

SYM_HUMAN
NC score	0.079959 (rank : 15)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	42	Target Neighborhood Hits	43	Shared Neighborhood Hits	11
SwissProt Accessions	P56192, Q14895, Q53H14, Q96A15, Q96BZ0, Q9NSE0	Gene names	MARS
Domain Architecture
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

MYH13_HUMAN
NC score	0.042445 (rank : 16)	θ value	0.21417 (rank : 11)
Query Neighborhood Hits	42	Target Neighborhood Hits	1504	Shared Neighborhood Hits	20
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH3_HUMAN
NC score	0.040814 (rank : 17)	θ value	0.0961366 (rank : 10)
Query Neighborhood Hits	42	Target Neighborhood Hits	1660	Shared Neighborhood Hits	19
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH4_MOUSE
NC score	0.040498 (rank : 18)	θ value	0.47712 (rank : 18)
Query Neighborhood Hits	42	Target Neighborhood Hits	1476	Shared Neighborhood Hits	19
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH8_HUMAN
NC score	0.039922 (rank : 19)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	42	Target Neighborhood Hits	1610	Shared Neighborhood Hits	19
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

EVPL_MOUSE
NC score	0.039165 (rank : 20)	θ value	0.365318 (rank : 12)
Query Neighborhood Hits	42	Target Neighborhood Hits	952	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

MYH2_HUMAN
NC score	0.038916 (rank : 21)	θ value	0.813845 (rank : 21)
Query Neighborhood Hits	42	Target Neighborhood Hits	1491	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH8_MOUSE
NC score	0.038734 (rank : 22)	θ value	0.47712 (rank : 19)
Query Neighborhood Hits	42	Target Neighborhood Hits	1600	Shared Neighborhood Hits	19
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH4_HUMAN
NC score	0.038687 (rank : 23)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	42	Target Neighborhood Hits	1377	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH1_HUMAN
NC score	0.038506 (rank : 24)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	42	Target Neighborhood Hits	1478	Shared Neighborhood Hits	18
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

RBP24_HUMAN
NC score	0.038427 (rank : 25)	θ value	0.365318 (rank : 15)
Query Neighborhood Hits	42	Target Neighborhood Hits	1559	Shared Neighborhood Hits	19
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.038370 (rank : 26)	θ value	0.365318 (rank : 13)
Query Neighborhood Hits	42	Target Neighborhood Hits	1558	Shared Neighborhood Hits	19
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

EVPL_HUMAN
NC score	0.037148 (rank : 27)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	42	Target Neighborhood Hits	895	Shared Neighborhood Hits	19
SwissProt Accessions	Q92817	Gene names	EVPL
Domain Architecture
Description	Envoplakin (210 kDa paraneoplastic pemphigus antigen) (p210) (210 kDa cornified envelope precursor protein).

MYH7_HUMAN
NC score	0.036634 (rank : 28)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	42	Target Neighborhood Hits	1559	Shared Neighborhood Hits	18
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH6_HUMAN
NC score	0.036583 (rank : 29)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	42	Target Neighborhood Hits	1426	Shared Neighborhood Hits	18
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

SDCG8_HUMAN
NC score	0.033626 (rank : 30)	θ value	0.365318 (rank : 16)
Query Neighborhood Hits	42	Target Neighborhood Hits	1002	Shared Neighborhood Hits	18
SwissProt Accessions	Q86SQ7, O60527, Q3ZCR6, Q8N5F2, Q9P0F1	Gene names	SDCCAG8, CCCAP
Domain Architecture	No domain graphic available
Description	Serologically defined colon cancer antigen 8 (Centrosomal colon cancer autoantigen protein) (hCCCAP) (Antigen NY-CO-8).

GCC2_MOUSE
NC score	0.032230 (rank : 31)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	42	Target Neighborhood Hits	1619	Shared Neighborhood Hits	19
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

MY18A_HUMAN
NC score	0.027098 (rank : 32)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	42	Target Neighborhood Hits	1929	Shared Neighborhood Hits	20
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SAMD4_MOUSE
NC score	0.024140 (rank : 33)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	42	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CBY1	Gene names	Samd4
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

SAMD4_HUMAN
NC score	0.020053 (rank : 34)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	42	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPU9	Gene names	SAMD4, KIAA1053
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

HEAT1_HUMAN
NC score	0.016726 (rank : 35)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	42	Target Neighborhood Hits	52	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H583, Q5T3Q8, Q9NW23	Gene names	HEATR1, BAP28
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 1 (Protein BAP28).

K0773_HUMAN
NC score	0.016211 (rank : 36)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	42	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q86XD5, Q7L0D6, Q86T97	Gene names	KIAA0773
Domain Architecture	No domain graphic available
Description	Uncharacterized protein KIAA0773.

IL21R_HUMAN
NC score	0.014980 (rank : 37)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	42	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HBE5, Q96HZ1, Q9HB91	Gene names	IL21R, NILR
Domain Architecture	No domain graphic available
Description	Interleukin-21 receptor precursor (IL-21R) (Novel interleukin receptor).

RFWD2_HUMAN
NC score	0.013675 (rank : 38)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	42	Target Neighborhood Hits	518	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NHY2, Q6H103, Q9H6L7	Gene names	RFWD2, COP1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1).

RFWD2_MOUSE
NC score	0.013670 (rank : 39)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	42	Target Neighborhood Hits	535	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R1A8	Gene names	Rfwd2, Cop1
Domain Architecture	No domain graphic available
Description	RING finger and WD repeat domain protein 2 (EC 6.3.2.-) (Ubiquitin- protein ligase COP1) (Constitutive photomorphogenesis protein 1 homolog) (mCOP1).

S3TC2_HUMAN
NC score	0.010953 (rank : 40)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	42	Target Neighborhood Hits	70	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TF17, Q9H8I5	Gene names	SH3TC2, KIAA1985
Domain Architecture
Description	SH3 domain and tetratricopeptide repeats-containing protein 2.

CHD8_HUMAN
NC score	0.008832 (rank : 41)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	42	Target Neighborhood Hits	235	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CS1B_MOUSE
NC score	0.007570 (rank : 42)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	42	Target Neighborhood Hits	361	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CS1A_MOUSE
NC score	0.006203 (rank : 43)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	42	Target Neighborhood Hits	360	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

ZBT40_HUMAN
NC score	0.001103 (rank : 44)	θ value	1.38821 (rank : 23)
Query Neighborhood Hits	42	Target Neighborhood Hits	949	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.