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Network neighborhood for query Sequence : EF1G_HUMAN

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EF1G_HUMAN
SwissProt Accessions	P26641, Q6PJ62, Q6PK31, Q96CU2, Q9P196	Gene names	EEF1G, EF1G
Domain Architecture
Description	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EF1G_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	P26641, Q6PJ62, Q6PK31, Q96CU2, Q9P196	Gene names	EEF1G, EF1G
Domain Architecture
Description	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).

EF1G_MOUSE
θ value	0 (rank : 2)	NC score	0.999017 (rank : 2)
Query Neighborhood Hits	30	Target Neighborhood Hits	31	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D8N0, Q920C5, Q9CRT5, Q9CSU3, Q9D004	Gene names	Eef1g
Domain Architecture
Description	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).

SYV_HUMAN
θ value	7.80994e-28 (rank : 3)	NC score	0.560372 (rank : 3)
Query Neighborhood Hits	30	Target Neighborhood Hits	41	Shared Neighborhood Hits	9
SwissProt Accessions	P26640, Q5JQ90, Q96E77, Q9UQM2	Gene names	VARS, G7A, VARS2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

SYV_MOUSE
θ value	5.59698e-26 (rank : 4)	NC score	0.552033 (rank : 4)
Query Neighborhood Hits	30	Target Neighborhood Hits	47	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1Q9, Q9QUN2	Gene names	Vars, Bat6, G7a, Vars2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

MCA3_MOUSE
θ value	1.43324e-05 (rank : 5)	NC score	0.339836 (rank : 5)
Query Neighborhood Hits	30	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D1M4	Gene names	Eef1e1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation elongation factor 1 epsilon-1 (Multisynthetase complex auxiliary component p18) (Elongation factor p18).

GSTT2_MOUSE
θ value	0.00228821 (rank : 6)	NC score	0.185368 (rank : 8)
Query Neighborhood Hits	30	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q61133, Q61134, Q64472	Gene names	Gstt2
Domain Architecture
Description	Glutathione S-transferase theta-2 (EC 2.5.1.18) (GST class-theta-2).

GSTT2_HUMAN
θ value	0.00298849 (rank : 7)	NC score	0.197731 (rank : 7)
Query Neighborhood Hits	30	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P30712, O60665, Q9HD76	Gene names	GSTT2
Domain Architecture
Description	Glutathione S-transferase theta-2 (EC 2.5.1.18) (GST class-theta-2).

MCA3_HUMAN
θ value	0.00509761 (rank : 8)	NC score	0.259930 (rank : 6)
Query Neighborhood Hits	30	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	O43324, Q5THS2	Gene names	EEF1E1
Domain Architecture
Description	Eukaryotic translation elongation factor 1 epsilon-1 (Multisynthetase complex auxiliary component p18) (Elongation factor p18).

PTGD2_HUMAN
θ value	0.0113563 (rank : 9)	NC score	0.132547 (rank : 13)
Query Neighborhood Hits	30	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	O60760	Gene names	PTGDS2, PGDS
Domain Architecture
Description	Glutathione-requiring prostaglandin D synthase (EC 5.3.99.2) (Glutathione-dependent PGD synthetase) (Prostaglandin-H2 D-isomerase) (Hematopoietic prostaglandin D synthase) (H-PGDS).

NCOAT_HUMAN
θ value	0.0330416 (rank : 10)	NC score	0.137632 (rank : 12)
Query Neighborhood Hits	30	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	O60502, O75166, Q86WV0, Q8IV98, Q9BVA5, Q9HAR0	Gene names	MGEA5, HEXC, KIAA0679, MEA5
Domain Architecture	No domain graphic available
Description	Bifunctional protein NCOAT (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) (Meningioma-expressed antigen 5) [Includes: Beta- hexosaminidase (EC 3.2.1.52) (N-acetyl-beta-glucosaminidase) (Beta-N- acetylhexosaminidase) (Hexosaminidase C) (N-acetyl-beta-D- glucosaminidase) (O-GlcNAcase); Histone acetyltransferase (EC 2.3.1.48) (HAT)].

NCOAT_MOUSE
θ value	0.0330416 (rank : 11)	NC score	0.137852 (rank : 11)
Query Neighborhood Hits	30	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQQ9, Q3ULY7, Q6ZQ71, Q8BK05, Q8BTT2, Q8CFX2, Q9CSJ4, Q9CUR7	Gene names	Mgea5, Hexc, Kiaa0679
Domain Architecture	No domain graphic available
Description	Bifunctional protein NCOAT (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) (Meningioma-expressed antigen 5) [Includes: Beta- hexosaminidase (EC 3.2.1.52) (N-acetyl-beta-glucosaminidase) (Beta-N- acetylhexosaminidase) (Hexosaminidase C) (N-acetyl-beta-D- glucosaminidase) (O-GlcNAcase); Histone acetyltransferase (EC 2.3.1.48) (HAT)].

PTGD2_MOUSE
θ value	0.0736092 (rank : 12)	NC score	0.118636 (rank : 16)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JHF7	Gene names	Ptgds2, Pgds
Domain Architecture
Description	Glutathione-requiring prostaglandin D synthase (EC 5.3.99.2) (Glutathione-dependent PGD synthetase) (Prostaglandin-H2 D-isomerase) (Hematopoietic prostaglandin D synthase) (H-PGDS).

HA1B_MOUSE
θ value	0.21417 (rank : 13)	NC score	0.019327 (rank : 36)
Query Neighborhood Hits	30	Target Neighborhood Hits	206	Shared Neighborhood Hits	5
SwissProt Accessions	P01901	Gene names	H2-K1, H2-K
Domain Architecture
Description	H-2 class I histocompatibility antigen, K-B alpha chain precursor (H- 2K(B)).

SYM_HUMAN
θ value	0.365318 (rank : 14)	NC score	0.102626 (rank : 18)
Query Neighborhood Hits	30	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	P56192, Q14895, Q53H14, Q96A15, Q96BZ0, Q9NSE0	Gene names	MARS
Domain Architecture
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

GSTA4_HUMAN
θ value	0.62314 (rank : 15)	NC score	0.059156 (rank : 25)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	O15217, Q5T7Q8, Q9BX18, Q9H414	Gene names	GSTA4
Domain Architecture
Description	Glutathione S-transferase A4 (EC 2.5.1.18) (Glutathione S-transferase A4-4) (GST class-alpha member 4).

GSTT1_MOUSE
θ value	0.62314 (rank : 16)	NC score	0.123067 (rank : 14)
Query Neighborhood Hits	30	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q64471	Gene names	Gstt1
Domain Architecture
Description	Glutathione S-transferase theta-1 (EC 2.5.1.18) (GST class-theta-1).

HA1D_MOUSE
θ value	0.62314 (rank : 17)	NC score	0.017170 (rank : 37)
Query Neighborhood Hits	30	Target Neighborhood Hits	210	Shared Neighborhood Hits	5
SwissProt Accessions	P01902	Gene names	H2-K1, H2-K
Domain Architecture
Description	H-2 class I histocompatibility antigen, K-D alpha chain precursor (H- 2K(D)).

GSTO1_HUMAN
θ value	1.38821 (rank : 18)	NC score	0.040578 (rank : 30)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P78417, Q5TA03, Q7Z3T2	Gene names	GSTO1, GSTTLP28
Domain Architecture
Description	Glutathione transferase omega-1 (EC 2.5.1.18) (GSTO 1-1).

CJ012_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.046901 (rank : 28)
Query Neighborhood Hits	30	Target Neighborhood Hits	467	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

SFRIP_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.036176 (rank : 31)
Query Neighborhood Hits	30	Target Neighborhood Hits	530	Shared Neighborhood Hits	5
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SIA7A_MOUSE
θ value	2.36792 (rank : 21)	NC score	0.032451 (rank : 32)
Query Neighborhood Hits	30	Target Neighborhood Hits	203	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZ39, Q9JJP5	Gene names	St6galnac1, Siat7a
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

SYM_MOUSE
θ value	2.36792 (rank : 22)	NC score	0.072645 (rank : 23)
Query Neighborhood Hits	30	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	Q68FL6	Gene names	Mars
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

SYEP_MOUSE
θ value	3.0926 (rank : 23)	NC score	0.073218 (rank : 22)
Query Neighborhood Hits	30	Target Neighborhood Hits	123	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CGC7	Gene names	Eprs, Qprs
Domain Architecture	No domain graphic available
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

SYEP_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.048473 (rank : 27)
Query Neighborhood Hits	30	Target Neighborhood Hits	70	Shared Neighborhood Hits	9
SwissProt Accessions	P07814	Gene names	EPRS, GLNS, PARS, QPRS
Domain Architecture
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

B3GL1_MOUSE
θ value	5.27518 (rank : 25)	NC score	0.020608 (rank : 35)
Query Neighborhood Hits	30	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q920V1, O54906, Q91V72, Q920V0, Q9CTE5	Gene names	b3galnt1, B3galt3, B3gt3
Domain Architecture	No domain graphic available
Description	UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.79) (Beta-3-GalNAc-T1) (Beta-1,3-galactosyltransferase 3) (Beta-1,3- GalTase 3) (Beta3Gal-T3) (b3Gal-T3) (Galactosylgalactosylglucosylceramide beta-D-acetyl- galactosaminyltransferase) (UDP-N- acetylgalactosamine:globotriaosylceramide beta-1,3-N- acetylgalactosaminyltransferase) (Globoside synthase) (Beta-3-Gx-T3).

GSTP1_HUMAN
θ value	6.88961 (rank : 26)	NC score	0.041258 (rank : 29)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	P09211, O00460, Q15690	Gene names	GSTP1, GST3
Domain Architecture
Description	Glutathione S-transferase P (EC 2.5.1.18) (GST class-pi) (GSTP1-1).

HA1L_MOUSE
θ value	6.88961 (rank : 27)	NC score	0.011636 (rank : 39)
Query Neighborhood Hits	30	Target Neighborhood Hits	217	Shared Neighborhood Hits	5
SwissProt Accessions	P01897, Q31195, Q31196, Q31197	Gene names	H2-L
Domain Architecture
Description	H-2 class I histocompatibility antigen, L-D alpha chain precursor.

UBF1_MOUSE
θ value	6.88961 (rank : 28)	NC score	0.021697 (rank : 34)
Query Neighborhood Hits	30	Target Neighborhood Hits	419	Shared Neighborhood Hits	6
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

SYCC_MOUSE
θ value	8.99809 (rank : 29)	NC score	0.026065 (rank : 33)
Query Neighborhood Hits	30	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ER72, O88303, Q8BP81, Q8CAY7, Q8CCE3, Q8K0S4, Q9ER68	Gene names	Cars
Domain Architecture
Description	Cysteinyl-tRNA synthetase, cytoplasmic (EC 6.1.1.16) (Cysteine--tRNA ligase) (CysRS).

UBF1_HUMAN
θ value	8.99809 (rank : 30)	NC score	0.015956 (rank : 38)
Query Neighborhood Hits	30	Target Neighborhood Hits	415	Shared Neighborhood Hits	5
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

GSTT1_HUMAN
θ value	θ > 10 (rank : 31)	NC score	0.081120 (rank : 21)
Query Neighborhood Hits	30	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	P30711, O00226, Q969K8, Q96IY3	Gene names	GSTT1
Domain Architecture
Description	Glutathione S-transferase theta-1 (EC 2.5.1.18) (GST class-theta-1) (Glutathione transferase T1-1).

SYIC_HUMAN
θ value	θ > 10 (rank : 32)	NC score	0.118829 (rank : 15)
Query Neighborhood Hits	30	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	P41252, Q5TCD0, Q9H588	Gene names	IARS
Domain Architecture
Description	Isoleucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS) (IRS).

SYIC_MOUSE
θ value	θ > 10 (rank : 33)	NC score	0.115802 (rank : 17)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BU30	Gene names	Iars
Domain Architecture
Description	Isoleucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS) (IRS).

SYIM_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.141125 (rank : 10)
Query Neighborhood Hits	30	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NSE4, Q6PI85, Q7L439, Q86WU9, Q96D91	Gene names	IARS2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

SYIM_MOUSE
θ value	θ > 10 (rank : 35)	NC score	0.142457 (rank : 9)
Query Neighborhood Hits	30	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BIJ6, Q3TKT8, Q8BIJ0, Q8BIP3	Gene names	Iars2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

SYLM_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.087338 (rank : 19)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q15031	Gene names	LARS2, KIAA0028
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYLM_MOUSE
θ value	θ > 10 (rank : 37)	NC score	0.082671 (rank : 20)
Query Neighborhood Hits	30	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VDC0	Gene names	Lars2
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYMM_HUMAN
θ value	θ > 10 (rank : 38)	NC score	0.056772 (rank : 26)
Query Neighborhood Hits	30	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q96GW9, Q76E79, Q8IW62, Q8N7N4	Gene names	MARS2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

SYMM_MOUSE
θ value	θ > 10 (rank : 39)	NC score	0.065027 (rank : 24)
Query Neighborhood Hits	30	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q499X9, Q3T9W7, Q8BWR9, Q8BXY1	Gene names	Mars2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

Hits sorted by NC score

EF1G_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	P26641, Q6PJ62, Q6PK31, Q96CU2, Q9P196	Gene names	EEF1G, EF1G
Domain Architecture
Description	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).

EF1G_MOUSE
NC score	0.999017 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	30	Target Neighborhood Hits	31	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D8N0, Q920C5, Q9CRT5, Q9CSU3, Q9D004	Gene names	Eef1g
Domain Architecture
Description	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).

SYV_HUMAN
NC score	0.560372 (rank : 3)	θ value	7.80994e-28 (rank : 3)
Query Neighborhood Hits	30	Target Neighborhood Hits	41	Shared Neighborhood Hits	9
SwissProt Accessions	P26640, Q5JQ90, Q96E77, Q9UQM2	Gene names	VARS, G7A, VARS2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

SYV_MOUSE
NC score	0.552033 (rank : 4)	θ value	5.59698e-26 (rank : 4)
Query Neighborhood Hits	30	Target Neighborhood Hits	47	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1Q9, Q9QUN2	Gene names	Vars, Bat6, G7a, Vars2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

MCA3_MOUSE
NC score	0.339836 (rank : 5)	θ value	1.43324e-05 (rank : 5)
Query Neighborhood Hits	30	Target Neighborhood Hits	14	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D1M4	Gene names	Eef1e1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation elongation factor 1 epsilon-1 (Multisynthetase complex auxiliary component p18) (Elongation factor p18).

MCA3_HUMAN
NC score	0.259930 (rank : 6)	θ value	0.00509761 (rank : 8)
Query Neighborhood Hits	30	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	O43324, Q5THS2	Gene names	EEF1E1
Domain Architecture
Description	Eukaryotic translation elongation factor 1 epsilon-1 (Multisynthetase complex auxiliary component p18) (Elongation factor p18).

GSTT2_HUMAN
NC score	0.197731 (rank : 7)	θ value	0.00298849 (rank : 7)
Query Neighborhood Hits	30	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P30712, O60665, Q9HD76	Gene names	GSTT2
Domain Architecture
Description	Glutathione S-transferase theta-2 (EC 2.5.1.18) (GST class-theta-2).

GSTT2_MOUSE
NC score	0.185368 (rank : 8)	θ value	0.00228821 (rank : 6)
Query Neighborhood Hits	30	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q61133, Q61134, Q64472	Gene names	Gstt2
Domain Architecture
Description	Glutathione S-transferase theta-2 (EC 2.5.1.18) (GST class-theta-2).

SYIM_MOUSE
NC score	0.142457 (rank : 9)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	30	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BIJ6, Q3TKT8, Q8BIJ0, Q8BIP3	Gene names	Iars2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

SYIM_HUMAN
NC score	0.141125 (rank : 10)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	30	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NSE4, Q6PI85, Q7L439, Q86WU9, Q96D91	Gene names	IARS2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

NCOAT_MOUSE
NC score	0.137852 (rank : 11)	θ value	0.0330416 (rank : 11)
Query Neighborhood Hits	30	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q9EQQ9, Q3ULY7, Q6ZQ71, Q8BK05, Q8BTT2, Q8CFX2, Q9CSJ4, Q9CUR7	Gene names	Mgea5, Hexc, Kiaa0679
Domain Architecture	No domain graphic available
Description	Bifunctional protein NCOAT (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) (Meningioma-expressed antigen 5) [Includes: Beta- hexosaminidase (EC 3.2.1.52) (N-acetyl-beta-glucosaminidase) (Beta-N- acetylhexosaminidase) (Hexosaminidase C) (N-acetyl-beta-D- glucosaminidase) (O-GlcNAcase); Histone acetyltransferase (EC 2.3.1.48) (HAT)].

NCOAT_HUMAN
NC score	0.137632 (rank : 12)	θ value	0.0330416 (rank : 10)
Query Neighborhood Hits	30	Target Neighborhood Hits	44	Shared Neighborhood Hits	4
SwissProt Accessions	O60502, O75166, Q86WV0, Q8IV98, Q9BVA5, Q9HAR0	Gene names	MGEA5, HEXC, KIAA0679, MEA5
Domain Architecture	No domain graphic available
Description	Bifunctional protein NCOAT (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) (Meningioma-expressed antigen 5) [Includes: Beta- hexosaminidase (EC 3.2.1.52) (N-acetyl-beta-glucosaminidase) (Beta-N- acetylhexosaminidase) (Hexosaminidase C) (N-acetyl-beta-D- glucosaminidase) (O-GlcNAcase); Histone acetyltransferase (EC 2.3.1.48) (HAT)].

PTGD2_HUMAN
NC score	0.132547 (rank : 13)	θ value	0.0113563 (rank : 9)
Query Neighborhood Hits	30	Target Neighborhood Hits	29	Shared Neighborhood Hits	7
SwissProt Accessions	O60760	Gene names	PTGDS2, PGDS
Domain Architecture
Description	Glutathione-requiring prostaglandin D synthase (EC 5.3.99.2) (Glutathione-dependent PGD synthetase) (Prostaglandin-H2 D-isomerase) (Hematopoietic prostaglandin D synthase) (H-PGDS).

GSTT1_MOUSE
NC score	0.123067 (rank : 14)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	30	Target Neighborhood Hits	25	Shared Neighborhood Hits	8
SwissProt Accessions	Q64471	Gene names	Gstt1
Domain Architecture
Description	Glutathione S-transferase theta-1 (EC 2.5.1.18) (GST class-theta-1).

SYIC_HUMAN
NC score	0.118829 (rank : 15)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	30	Target Neighborhood Hits	42	Shared Neighborhood Hits	3
SwissProt Accessions	P41252, Q5TCD0, Q9H588	Gene names	IARS
Domain Architecture
Description	Isoleucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS) (IRS).

PTGD2_MOUSE
NC score	0.118636 (rank : 16)	θ value	0.0736092 (rank : 12)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JHF7	Gene names	Ptgds2, Pgds
Domain Architecture
Description	Glutathione-requiring prostaglandin D synthase (EC 5.3.99.2) (Glutathione-dependent PGD synthetase) (Prostaglandin-H2 D-isomerase) (Hematopoietic prostaglandin D synthase) (H-PGDS).

SYIC_MOUSE
NC score	0.115802 (rank : 17)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BU30	Gene names	Iars
Domain Architecture
Description	Isoleucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS) (IRS).

SYM_HUMAN
NC score	0.102626 (rank : 18)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	30	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	P56192, Q14895, Q53H14, Q96A15, Q96BZ0, Q9NSE0	Gene names	MARS
Domain Architecture
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

SYLM_HUMAN
NC score	0.087338 (rank : 19)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q15031	Gene names	LARS2, KIAA0028
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYLM_MOUSE
NC score	0.082671 (rank : 20)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	30	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VDC0	Gene names	Lars2
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

GSTT1_HUMAN
NC score	0.081120 (rank : 21)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	30	Target Neighborhood Hits	22	Shared Neighborhood Hits	4
SwissProt Accessions	P30711, O00226, Q969K8, Q96IY3	Gene names	GSTT1
Domain Architecture
Description	Glutathione S-transferase theta-1 (EC 2.5.1.18) (GST class-theta-1) (Glutathione transferase T1-1).

SYEP_MOUSE
NC score	0.073218 (rank : 22)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	30	Target Neighborhood Hits	123	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CGC7	Gene names	Eprs, Qprs
Domain Architecture	No domain graphic available
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

SYM_MOUSE
NC score	0.072645 (rank : 23)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	30	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	Q68FL6	Gene names	Mars
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

SYMM_MOUSE
NC score	0.065027 (rank : 24)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	30	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q499X9, Q3T9W7, Q8BWR9, Q8BXY1	Gene names	Mars2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

GSTA4_HUMAN
NC score	0.059156 (rank : 25)	θ value	0.62314 (rank : 15)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	O15217, Q5T7Q8, Q9BX18, Q9H414	Gene names	GSTA4
Domain Architecture
Description	Glutathione S-transferase A4 (EC 2.5.1.18) (Glutathione S-transferase A4-4) (GST class-alpha member 4).

SYMM_HUMAN
NC score	0.056772 (rank : 26)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	30	Target Neighborhood Hits	27	Shared Neighborhood Hits	4
SwissProt Accessions	Q96GW9, Q76E79, Q8IW62, Q8N7N4	Gene names	MARS2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

SYEP_HUMAN
NC score	0.048473 (rank : 27)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	30	Target Neighborhood Hits	70	Shared Neighborhood Hits	9
SwissProt Accessions	P07814	Gene names	EPRS, GLNS, PARS, QPRS
Domain Architecture
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

CJ012_HUMAN
NC score	0.046901 (rank : 28)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	30	Target Neighborhood Hits	467	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N655, Q9H945, Q9Y457	Gene names	C10orf12
Domain Architecture	No domain graphic available
Description	Protein C10orf12.

GSTP1_HUMAN
NC score	0.041258 (rank : 29)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	30	Target Neighborhood Hits	26	Shared Neighborhood Hits	6
SwissProt Accessions	P09211, O00460, Q15690	Gene names	GSTP1, GST3
Domain Architecture
Description	Glutathione S-transferase P (EC 2.5.1.18) (GST class-pi) (GSTP1-1).

GSTO1_HUMAN
NC score	0.040578 (rank : 30)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	30	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	P78417, Q5TA03, Q7Z3T2	Gene names	GSTO1, GSTTLP28
Domain Architecture
Description	Glutathione transferase omega-1 (EC 2.5.1.18) (GSTO 1-1).

SFRIP_HUMAN
NC score	0.036176 (rank : 31)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	30	Target Neighborhood Hits	530	Shared Neighborhood Hits	5
SwissProt Accessions	Q99590, Q8IW59	Gene names	SFRS2IP, CASP11, SIP1
Domain Architecture	No domain graphic available
Description	SFRS2-interacting protein (Splicing factor, arginine/serine-rich 2- interacting protein) (SC35-interacting protein 1) (CTD-associated SR protein 11) (Splicing regulatory protein 129) (SRrp129) (NY-REN-40 antigen).

SIA7A_MOUSE
NC score	0.032451 (rank : 32)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	30	Target Neighborhood Hits	203	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZ39, Q9JJP5	Gene names	St6galnac1, Siat7a
Domain Architecture
Description	Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (EC 2.4.99.3) (GalNAc alpha-2,6-sialyltransferase I) (ST6GalNAc I) (Sialyltransferase 7A).

SYCC_MOUSE
NC score	0.026065 (rank : 33)	θ value	8.99809 (rank : 29)
Query Neighborhood Hits	30	Target Neighborhood Hits	63	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ER72, O88303, Q8BP81, Q8CAY7, Q8CCE3, Q8K0S4, Q9ER68	Gene names	Cars
Domain Architecture
Description	Cysteinyl-tRNA synthetase, cytoplasmic (EC 6.1.1.16) (Cysteine--tRNA ligase) (CysRS).

UBF1_MOUSE
NC score	0.021697 (rank : 34)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	30	Target Neighborhood Hits	419	Shared Neighborhood Hits	6
SwissProt Accessions	P25976	Gene names	Ubtf, Tcfubf, Ubf-1, Ubf1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1).

B3GL1_MOUSE
NC score	0.020608 (rank : 35)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	30	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	Q920V1, O54906, Q91V72, Q920V0, Q9CTE5	Gene names	b3galnt1, B3galt3, B3gt3
Domain Architecture	No domain graphic available
Description	UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (EC 2.4.1.79) (Beta-3-GalNAc-T1) (Beta-1,3-galactosyltransferase 3) (Beta-1,3- GalTase 3) (Beta3Gal-T3) (b3Gal-T3) (Galactosylgalactosylglucosylceramide beta-D-acetyl- galactosaminyltransferase) (UDP-N- acetylgalactosamine:globotriaosylceramide beta-1,3-N- acetylgalactosaminyltransferase) (Globoside synthase) (Beta-3-Gx-T3).

HA1B_MOUSE
NC score	0.019327 (rank : 36)	θ value	0.21417 (rank : 13)
Query Neighborhood Hits	30	Target Neighborhood Hits	206	Shared Neighborhood Hits	5
SwissProt Accessions	P01901	Gene names	H2-K1, H2-K
Domain Architecture
Description	H-2 class I histocompatibility antigen, K-B alpha chain precursor (H- 2K(B)).

HA1D_MOUSE
NC score	0.017170 (rank : 37)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	30	Target Neighborhood Hits	210	Shared Neighborhood Hits	5
SwissProt Accessions	P01902	Gene names	H2-K1, H2-K
Domain Architecture
Description	H-2 class I histocompatibility antigen, K-D alpha chain precursor (H- 2K(D)).

UBF1_HUMAN
NC score	0.015956 (rank : 38)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	30	Target Neighborhood Hits	415	Shared Neighborhood Hits	5
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

HA1L_MOUSE
NC score	0.011636 (rank : 39)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	30	Target Neighborhood Hits	217	Shared Neighborhood Hits	5
SwissProt Accessions	P01897, Q31195, Q31196, Q31197	Gene names	H2-L
Domain Architecture
Description	H-2 class I histocompatibility antigen, L-D alpha chain precursor.