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Network neighborhood for query Sequence : SYM_MOUSE

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SYM_MOUSE
SwissProt Accessions	Q68FL6	Gene names	Mars
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SYM_HUMAN
θ value	0 (rank : 1)	NC score	0.990328 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	P56192, Q14895, Q53H14, Q96A15, Q96BZ0, Q9NSE0	Gene names	MARS
Domain Architecture
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

SYM_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	Q68FL6	Gene names	Mars
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

SYMM_MOUSE
θ value	1.52067e-31 (rank : 3)	NC score	0.668190 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	Q499X9, Q3T9W7, Q8BWR9, Q8BXY1	Gene names	Mars2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

SYMM_HUMAN
θ value	3.74554e-30 (rank : 4)	NC score	0.666099 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q96GW9, Q76E79, Q8IW62, Q8N7N4	Gene names	MARS2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

SYEP_MOUSE
θ value	9.29e-05 (rank : 5)	NC score	0.199997 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	123	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CGC7	Gene names	Eprs, Qprs
Domain Architecture	No domain graphic available
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

SYH_MOUSE
θ value	0.00020696 (rank : 6)	NC score	0.170336 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	Q61035	Gene names	Hars
Domain Architecture
Description	Histidyl-tRNA synthetase (EC 6.1.1.21) (Histidine--tRNA ligase) (HisRS).

SYEP_HUMAN
θ value	0.00102713 (rank : 7)	NC score	0.191728 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	P07814	Gene names	EPRS, GLNS, PARS, QPRS
Domain Architecture
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

SYH_HUMAN
θ value	0.00175202 (rank : 8)	NC score	0.160205 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	P12081	Gene names	HARS, HRS
Domain Architecture
Description	Histidyl-tRNA synthetase (EC 6.1.1.21) (Histidine--tRNA ligase) (HisRS).

SYV_MOUSE
θ value	0.365318 (rank : 9)	NC score	0.106060 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1Q9, Q9QUN2	Gene names	Vars, Bat6, G7a, Vars2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

SYIM_MOUSE
θ value	0.62314 (rank : 10)	NC score	0.092388 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BIJ6, Q3TKT8, Q8BIJ0, Q8BIP3	Gene names	Iars2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

ANGP4_HUMAN
θ value	1.06291 (rank : 11)	NC score	0.014495 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	187	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y264, Q9H4Z4	Gene names	ANGPT4, ANG3, ANG4
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

SYIM_HUMAN
θ value	1.06291 (rank : 12)	NC score	0.081659 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NSE4, Q6PI85, Q7L439, Q86WU9, Q96D91	Gene names	IARS2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

SYNG_MOUSE
θ value	1.06291 (rank : 13)	NC score	0.046271 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

SYW_MOUSE
θ value	1.06291 (rank : 14)	NC score	0.108666 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P32921, Q80ZY4, Q99J58, Q9DC65	Gene names	Wars, Wrs
Domain Architecture
Description	Tryptophanyl-tRNA synthetase (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS).

CROCC_HUMAN
θ value	1.38821 (rank : 15)	NC score	0.013893 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	1409	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

SYNG_HUMAN
θ value	1.38821 (rank : 16)	NC score	0.045680 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	160	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

SYW_HUMAN
θ value	1.38821 (rank : 17)	NC score	0.112180 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P23381, P78535, Q9UDL3	Gene names	WARS, WRS
Domain Architecture
Description	Tryptophanyl-tRNA synthetase (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS) (IFP53) (hWRS).

LAMB3_HUMAN
θ value	1.81305 (rank : 18)	NC score	0.011077 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	461	Shared Neighborhood Hits	5
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

NEP_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.025531 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	P08473	Gene names	MME, EPN
Domain Architecture
Description	Neprilysin (EC 3.4.24.11) (Neutral endopeptidase) (NEP) (Enkephalinase) (Neutral endopeptidase 24.11) (Atriopeptidase) (Common acute lymphocytic leukemia antigen) (CALLA) (CD10 antigen).

SLIK6_HUMAN
θ value	1.81305 (rank : 20)	NC score	0.013316 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	297	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H5Y7, Q495Q0, Q6AW93, Q9HAA8, Q9NT60	Gene names	SLITRK6
Domain Architecture	No domain graphic available
Description	SLIT and NTRK-like protein 6 precursor.

EF1G_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.072645 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	P26641, Q6PJ62, Q6PK31, Q96CU2, Q9P196	Gene names	EEF1G, EF1G
Domain Architecture
Description	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).

GSTO2_MOUSE
θ value	2.36792 (rank : 22)	NC score	0.024969 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K2Q2	Gene names	Gsto2
Domain Architecture	No domain graphic available
Description	Glutathione transferase omega-2 (EC 2.5.1.18).

SLIK6_MOUSE
θ value	2.36792 (rank : 23)	NC score	0.012816 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	302	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C110, Q8BLL0	Gene names	Slitrk6, Sltk6
Domain Architecture
Description	SLIT and NTRK-like protein 6 precursor.

UBE3A_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.016368 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

CP250_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.011573 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	1805	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

PDPN_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.042398 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q86YL7, O60836, O95128, Q7L375, Q8NBQ8, Q8NBR3	Gene names	PDPN, GP36
Domain Architecture	No domain graphic available
Description	Podoplanin precursor (Glycoprotein 36) (Gp36) (PA2.26 antigen) (T1A) (T1-alpha) (Aggrus).

SRBP2_HUMAN
θ value	3.0926 (rank : 27)	NC score	0.025570 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

ACTN4_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.017029 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	279	Shared Neighborhood Hits	7
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

EF1G_MOUSE
θ value	4.03905 (rank : 29)	NC score	0.065263 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D8N0, Q920C5, Q9CRT5, Q9CSU3, Q9D004	Gene names	Eef1g
Domain Architecture
Description	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).

KPCL_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.003313 (rank : 45)
Query Neighborhood Hits	41	Target Neighborhood Hits	891	Shared Neighborhood Hits	5
SwissProt Accessions	P23298	Gene names	Prkch, Pkch
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

MAP4_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.014359 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	428	Shared Neighborhood Hits	3
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

TAXB1_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.009423 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	829	Shared Neighborhood Hits	5
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

CP250_MOUSE
θ value	5.27518 (rank : 33)	NC score	0.010987 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	1583	Shared Neighborhood Hits	12
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

KPCL_HUMAN
θ value	5.27518 (rank : 34)	NC score	0.002996 (rank : 46)
Query Neighborhood Hits	41	Target Neighborhood Hits	887	Shared Neighborhood Hits	5
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

RBM19_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.008691 (rank : 42)
Query Neighborhood Hits	41	Target Neighborhood Hits	296	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

MCA3_MOUSE
θ value	6.88961 (rank : 36)	NC score	0.065315 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D1M4	Gene names	Eef1e1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation elongation factor 1 epsilon-1 (Multisynthetase complex auxiliary component p18) (Elongation factor p18).

MYO15_MOUSE
θ value	6.88961 (rank : 37)	NC score	0.006366 (rank : 43)
Query Neighborhood Hits	41	Target Neighborhood Hits	467	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

SYIC_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.056304 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BU30	Gene names	Iars
Domain Architecture
Description	Isoleucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS) (IRS).

UBE3A_MOUSE
θ value	6.88961 (rank : 39)	NC score	0.014106 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

VAV3_MOUSE
θ value	6.88961 (rank : 40)	NC score	0.005695 (rank : 44)
Query Neighborhood Hits	41	Target Neighborhood Hits	404	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

ACTN4_MOUSE
θ value	8.99809 (rank : 41)	NC score	0.014212 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	276	Shared Neighborhood Hits	7
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

SYHH_HUMAN
θ value	θ > 10 (rank : 42)	NC score	0.073684 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P49590	Gene names	HARSL, HARSR, HO3
Domain Architecture
Description	Histidyl-tRNA synthetase homolog (EC 6.1.1.21) (Histidine--tRNA ligase homolog) (HisRS).

SYLM_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.057042 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q15031	Gene names	LARS2, KIAA0028
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYLM_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.055807 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VDC0	Gene names	Lars2
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYQ_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.062954 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P47897	Gene names	QARS
Domain Architecture
Description	Glutaminyl-tRNA synthetase (EC 6.1.1.18) (Glutamine--tRNA ligase) (GlnRS).

SYV_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.100086 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	P26640, Q5JQ90, Q96E77, Q9UQM2	Gene names	VARS, G7A, VARS2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

Hits sorted by NC score

SYM_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	41
SwissProt Accessions	Q68FL6	Gene names	Mars
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

SYM_HUMAN
NC score	0.990328 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	41	Target Neighborhood Hits	43	Shared Neighborhood Hits	24
SwissProt Accessions	P56192, Q14895, Q53H14, Q96A15, Q96BZ0, Q9NSE0	Gene names	MARS
Domain Architecture
Description	Methionyl-tRNA synthetase (EC 6.1.1.10) (Methionine--tRNA ligase) (MetRS).

SYMM_MOUSE
NC score	0.668190 (rank : 3)	θ value	1.52067e-31 (rank : 3)
Query Neighborhood Hits	41	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	Q499X9, Q3T9W7, Q8BWR9, Q8BXY1	Gene names	Mars2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

SYMM_HUMAN
NC score	0.666099 (rank : 4)	θ value	3.74554e-30 (rank : 4)
Query Neighborhood Hits	41	Target Neighborhood Hits	27	Shared Neighborhood Hits	8
SwissProt Accessions	Q96GW9, Q76E79, Q8IW62, Q8N7N4	Gene names	MARS2
Domain Architecture	No domain graphic available
Description	Methionyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.10) (Methionine--tRNA ligase 2) (Mitochondrial methionine--tRNA ligase) (MtMetRS).

SYEP_MOUSE
NC score	0.199997 (rank : 5)	θ value	9.29e-05 (rank : 5)
Query Neighborhood Hits	41	Target Neighborhood Hits	123	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CGC7	Gene names	Eprs, Qprs
Domain Architecture	No domain graphic available
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

SYEP_HUMAN
NC score	0.191728 (rank : 6)	θ value	0.00102713 (rank : 7)
Query Neighborhood Hits	41	Target Neighborhood Hits	70	Shared Neighborhood Hits	11
SwissProt Accessions	P07814	Gene names	EPRS, GLNS, PARS, QPRS
Domain Architecture
Description	Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase (EC 6.1.1.17) (Glutamate--tRNA ligase); Prolyl-tRNA synthetase (EC 6.1.1.15) (Proline--tRNA ligase)].

SYH_MOUSE
NC score	0.170336 (rank : 7)	θ value	0.00020696 (rank : 6)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	Q61035	Gene names	Hars
Domain Architecture
Description	Histidyl-tRNA synthetase (EC 6.1.1.21) (Histidine--tRNA ligase) (HisRS).

SYH_HUMAN
NC score	0.160205 (rank : 8)	θ value	0.00175202 (rank : 8)
Query Neighborhood Hits	41	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	P12081	Gene names	HARS, HRS
Domain Architecture
Description	Histidyl-tRNA synthetase (EC 6.1.1.21) (Histidine--tRNA ligase) (HisRS).

SYW_HUMAN
NC score	0.112180 (rank : 9)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	41	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P23381, P78535, Q9UDL3	Gene names	WARS, WRS
Domain Architecture
Description	Tryptophanyl-tRNA synthetase (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS) (IFP53) (hWRS).

SYW_MOUSE
NC score	0.108666 (rank : 10)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	41	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	P32921, Q80ZY4, Q99J58, Q9DC65	Gene names	Wars, Wrs
Domain Architecture
Description	Tryptophanyl-tRNA synthetase (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS).

SYV_MOUSE
NC score	0.106060 (rank : 11)	θ value	0.365318 (rank : 9)
Query Neighborhood Hits	41	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Z1Q9, Q9QUN2	Gene names	Vars, Bat6, G7a, Vars2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

SYV_HUMAN
NC score	0.100086 (rank : 12)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	41	Target Neighborhood Hits	41	Shared Neighborhood Hits	11
SwissProt Accessions	P26640, Q5JQ90, Q96E77, Q9UQM2	Gene names	VARS, G7A, VARS2
Domain Architecture
Description	Valyl-tRNA synthetase (EC 6.1.1.9) (Valine--tRNA ligase) (ValRS) (Protein G7a).

SYIM_MOUSE
NC score	0.092388 (rank : 13)	θ value	0.62314 (rank : 10)
Query Neighborhood Hits	41	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BIJ6, Q3TKT8, Q8BIJ0, Q8BIP3	Gene names	Iars2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

SYIM_HUMAN
NC score	0.081659 (rank : 14)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	41	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NSE4, Q6PI85, Q7L439, Q86WU9, Q96D91	Gene names	IARS2
Domain Architecture	No domain graphic available
Description	Isoleucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS).

SYHH_HUMAN
NC score	0.073684 (rank : 15)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	41	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P49590	Gene names	HARSL, HARSR, HO3
Domain Architecture
Description	Histidyl-tRNA synthetase homolog (EC 6.1.1.21) (Histidine--tRNA ligase homolog) (HisRS).

EF1G_HUMAN
NC score	0.072645 (rank : 16)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	41	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	P26641, Q6PJ62, Q6PK31, Q96CU2, Q9P196	Gene names	EEF1G, EF1G
Domain Architecture
Description	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).

MCA3_MOUSE
NC score	0.065315 (rank : 17)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	41	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D1M4	Gene names	Eef1e1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation elongation factor 1 epsilon-1 (Multisynthetase complex auxiliary component p18) (Elongation factor p18).

EF1G_MOUSE
NC score	0.065263 (rank : 18)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	41	Target Neighborhood Hits	31	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D8N0, Q920C5, Q9CRT5, Q9CSU3, Q9D004	Gene names	Eef1g
Domain Architecture
Description	Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma).

SYQ_HUMAN
NC score	0.062954 (rank : 19)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	41	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	P47897	Gene names	QARS
Domain Architecture
Description	Glutaminyl-tRNA synthetase (EC 6.1.1.18) (Glutamine--tRNA ligase) (GlnRS).

SYLM_HUMAN
NC score	0.057042 (rank : 20)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	41	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q15031	Gene names	LARS2, KIAA0028
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYIC_MOUSE
NC score	0.056304 (rank : 21)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	41	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BU30	Gene names	Iars
Domain Architecture
Description	Isoleucyl-tRNA synthetase, cytoplasmic (EC 6.1.1.5) (Isoleucine--tRNA ligase) (IleRS) (IRS).

SYLM_MOUSE
NC score	0.055807 (rank : 22)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	41	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VDC0	Gene names	Lars2
Domain Architecture
Description	Probable leucyl-tRNA synthetase, mitochondrial precursor (EC 6.1.1.4) (Leucine--tRNA ligase) (LeuRS).

SYNG_MOUSE
NC score	0.046271 (rank : 23)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	41	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	Q5SV85, Q5SV84, Q6PHT6	Gene names	Ap1gbp1, Syng
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

SYNG_HUMAN
NC score	0.045680 (rank : 24)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	41	Target Neighborhood Hits	160	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UMZ2, Q6ZT17	Gene names	AP1GBP1, SYNG
Domain Architecture	No domain graphic available
Description	AP1 subunit gamma-binding protein 1 (Gamma-synergin).

PDPN_HUMAN
NC score	0.042398 (rank : 25)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	41	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q86YL7, O60836, O95128, Q7L375, Q8NBQ8, Q8NBR3	Gene names	PDPN, GP36
Domain Architecture	No domain graphic available
Description	Podoplanin precursor (Glycoprotein 36) (Gp36) (PA2.26 antigen) (T1A) (T1-alpha) (Aggrus).

SRBP2_HUMAN
NC score	0.025570 (rank : 26)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	41	Target Neighborhood Hits	133	Shared Neighborhood Hits	3
SwissProt Accessions	Q12772, Q9UH04	Gene names	SREBF2, SREBP2
Domain Architecture
Description	Sterol regulatory element-binding protein 2 (SREBP-2) (Sterol regulatory element-binding transcription factor 2).

NEP_HUMAN
NC score	0.025531 (rank : 27)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	41	Target Neighborhood Hits	25	Shared Neighborhood Hits	3
SwissProt Accessions	P08473	Gene names	MME, EPN
Domain Architecture
Description	Neprilysin (EC 3.4.24.11) (Neutral endopeptidase) (NEP) (Enkephalinase) (Neutral endopeptidase 24.11) (Atriopeptidase) (Common acute lymphocytic leukemia antigen) (CALLA) (CD10 antigen).

GSTO2_MOUSE
NC score	0.024969 (rank : 28)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	41	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K2Q2	Gene names	Gsto2
Domain Architecture	No domain graphic available
Description	Glutathione transferase omega-2 (EC 2.5.1.18).

ACTN4_HUMAN
NC score	0.017029 (rank : 29)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	41	Target Neighborhood Hits	279	Shared Neighborhood Hits	7
SwissProt Accessions	O43707, O76048	Gene names	ACTN4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

UBE3A_HUMAN
NC score	0.016368 (rank : 30)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	41	Target Neighborhood Hits	49	Shared Neighborhood Hits	3
SwissProt Accessions	Q05086, P78355, Q93066, Q9UEP4, Q9UEP5, Q9UEP6, Q9UEP7, Q9UEP8, Q9UEP9	Gene names	UBE3A, E6AP
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (E6AP ubiquitin-protein ligase) (Oncogenic protein-associated protein E6-AP) (Human papillomavirus E6-associated protein) (NY-REN-54 antigen).

ANGP4_HUMAN
NC score	0.014495 (rank : 31)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	41	Target Neighborhood Hits	187	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y264, Q9H4Z4	Gene names	ANGPT4, ANG3, ANG4
Domain Architecture
Description	Angiopoietin-4 precursor (ANG-4) (ANG-3).

MAP4_HUMAN
NC score	0.014359 (rank : 32)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	41	Target Neighborhood Hits	428	Shared Neighborhood Hits	3
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

ACTN4_MOUSE
NC score	0.014212 (rank : 33)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	41	Target Neighborhood Hits	276	Shared Neighborhood Hits	7
SwissProt Accessions	P57780	Gene names	Actn4
Domain Architecture
Description	Alpha-actinin-4 (Non-muscle alpha-actinin 4) (F-actin cross-linking protein).

UBE3A_MOUSE
NC score	0.014106 (rank : 34)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	41	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	O08759, P97482	Gene names	Ube3a
Domain Architecture
Description	Ubiquitin-protein ligase E3A (EC 6.3.2.-) (Oncogenic protein- associated protein E6-AP).

CROCC_HUMAN
NC score	0.013893 (rank : 35)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	41	Target Neighborhood Hits	1409	Shared Neighborhood Hits	10
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

SLIK6_HUMAN
NC score	0.013316 (rank : 36)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	41	Target Neighborhood Hits	297	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H5Y7, Q495Q0, Q6AW93, Q9HAA8, Q9NT60	Gene names	SLITRK6
Domain Architecture	No domain graphic available
Description	SLIT and NTRK-like protein 6 precursor.

SLIK6_MOUSE
NC score	0.012816 (rank : 37)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	41	Target Neighborhood Hits	302	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C110, Q8BLL0	Gene names	Slitrk6, Sltk6
Domain Architecture
Description	SLIT and NTRK-like protein 6 precursor.

CP250_HUMAN
NC score	0.011573 (rank : 38)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	41	Target Neighborhood Hits	1805	Shared Neighborhood Hits	12
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

LAMB3_HUMAN
NC score	0.011077 (rank : 39)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	41	Target Neighborhood Hits	461	Shared Neighborhood Hits	5
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

CP250_MOUSE
NC score	0.010987 (rank : 40)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	41	Target Neighborhood Hits	1583	Shared Neighborhood Hits	12
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

TAXB1_HUMAN
NC score	0.009423 (rank : 41)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	41	Target Neighborhood Hits	829	Shared Neighborhood Hits	5
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

RBM19_MOUSE
NC score	0.008691 (rank : 42)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	41	Target Neighborhood Hits	296	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R3C6, Q8BHR0, Q9CW63	Gene names	Rbm19
Domain Architecture	No domain graphic available
Description	Probable RNA-binding protein 19 (RNA-binding motif protein 19).

MYO15_MOUSE
NC score	0.006366 (rank : 43)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	41	Target Neighborhood Hits	467	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

VAV3_MOUSE
NC score	0.005695 (rank : 44)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	41	Target Neighborhood Hits	404	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

KPCL_MOUSE
NC score	0.003313 (rank : 45)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	41	Target Neighborhood Hits	891	Shared Neighborhood Hits	5
SwissProt Accessions	P23298	Gene names	Prkch, Pkch
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

KPCL_HUMAN
NC score	0.002996 (rank : 46)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	41	Target Neighborhood Hits	887	Shared Neighborhood Hits	5
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).