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Network neighborhood for query Sequence : CAND2_MOUSE

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CAND2_MOUSE
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CAND1_HUMAN
θ value	0 (rank : 1)	NC score	0.981598 (rank : 3)
Query Neighborhood Hits	44	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	Q86VP6, O94918, Q6PIY4, Q8NDJ4, Q96JZ9, Q96T19, Q9BTC4, Q9H0G2, Q9P0H7, Q9UF85	Gene names	CAND1, KIAA0829, TIP120, TIP120A
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1) (TBP-interacting protein TIP120A) (TBP-interacting protein of 120 kDa A).

CAND1_MOUSE
θ value	0 (rank : 2)	NC score	0.981032 (rank : 4)
Query Neighborhood Hits	44	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZQ38, Q6PFR0, Q9CV45	Gene names	Cand1, D10Ertd516e, Kiaa0829
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1).

CAND2_HUMAN
θ value	0 (rank : 3)	NC score	0.992498 (rank : 2)
Query Neighborhood Hits	44	Target Neighborhood Hits	40	Shared Neighborhood Hits	22
SwissProt Accessions	O75155	Gene names	CAND2, KIAA0667
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2).

CAND2_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

IPO4_HUMAN
θ value	5.81887e-07 (rank : 5)	NC score	0.210715 (rank : 5)
Query Neighborhood Hits	44	Target Neighborhood Hits	49	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

IMB3_HUMAN
θ value	0.00665767 (rank : 6)	NC score	0.116679 (rank : 8)
Query Neighborhood Hits	44	Target Neighborhood Hits	57	Shared Neighborhood Hits	14
SwissProt Accessions	O00410, O15257	Gene names	RANBP5, KPNB3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

IMB3_MOUSE
θ value	0.0148317 (rank : 7)	NC score	0.112034 (rank : 9)
Query Neighborhood Hits	44	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BKC5, Q3TEG2, Q7TQC6, Q9EQ30	Gene names	Ranbp5, Kpnb3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

2AAA_HUMAN
θ value	0.0252991 (rank : 8)	NC score	0.082865 (rank : 10)
Query Neighborhood Hits	44	Target Neighborhood Hits	42	Shared Neighborhood Hits	12
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

2AAA_MOUSE
θ value	0.0252991 (rank : 9)	NC score	0.081100 (rank : 11)
Query Neighborhood Hits	44	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

GCN1L_HUMAN
θ value	0.0330416 (rank : 10)	NC score	0.162424 (rank : 7)
Query Neighborhood Hits	44	Target Neighborhood Hits	112	Shared Neighborhood Hits	20
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

CE110_MOUSE
θ value	0.21417 (rank : 11)	NC score	0.046204 (rank : 21)
Query Neighborhood Hits	44	Target Neighborhood Hits	170	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TSH4, Q6A072	Gene names	Cep110, Cp110, Kiaa0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

FRAP_HUMAN
θ value	0.813845 (rank : 12)	NC score	0.073820 (rank : 13)
Query Neighborhood Hits	44	Target Neighborhood Hits	83	Shared Neighborhood Hits	13
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_MOUSE
θ value	0.813845 (rank : 13)	NC score	0.074087 (rank : 12)
Query Neighborhood Hits	44	Target Neighborhood Hits	77	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

IPO4_MOUSE
θ value	1.06291 (rank : 14)	NC score	0.172001 (rank : 6)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VI75, Q3TBW0, Q99J52	Gene names	Ipo4, Imp4a, Ranbp4
Domain Architecture	No domain graphic available
Description	Importin-4 (Importin 4a) (Imp4a) (Ran-binding protein 4) (RanBP4).

TNPO1_HUMAN
θ value	1.06291 (rank : 15)	NC score	0.061653 (rank : 18)
Query Neighborhood Hits	44	Target Neighborhood Hits	64	Shared Neighborhood Hits	15
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO1_MOUSE
θ value	1.06291 (rank : 16)	NC score	0.061665 (rank : 17)
Query Neighborhood Hits	44	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

AP2A2_HUMAN
θ value	1.38821 (rank : 17)	NC score	0.021412 (rank : 29)
Query Neighborhood Hits	44	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	O94973, O75403, Q96SI8	Gene names	AP2A2, ADTAB, KIAA0899
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) (Huntingtin-interacting protein HYPJ).

AP2A2_MOUSE
θ value	1.38821 (rank : 18)	NC score	0.021382 (rank : 30)
Query Neighborhood Hits	44	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P17427, Q921V0	Gene names	Ap2a2, Adtab
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit).

MYH3_HUMAN
θ value	1.38821 (rank : 19)	NC score	0.003201 (rank : 46)
Query Neighborhood Hits	44	Target Neighborhood Hits	1660	Shared Neighborhood Hits	7
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

UBR2_MOUSE
θ value	1.38821 (rank : 20)	NC score	0.028687 (rank : 24)
Query Neighborhood Hits	44	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q6WKZ8, Q6DIB9, Q80U31, Q8BUL9, Q8CGW0, Q8K2I6, Q8R0V7, Q8R130	Gene names	Ubr2, Kiaa0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

EFG1_HUMAN
θ value	1.81305 (rank : 21)	NC score	0.017727 (rank : 36)
Query Neighborhood Hits	44	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RP9, Q96T39	Gene names	GFM1, EFG, EFG1, GFM
Domain Architecture
Description	Elongation factor G 1, mitochondrial precursor (mEF-G 1) (Elongation factor G1).

SFR17_HUMAN
θ value	1.81305 (rank : 22)	NC score	0.022454 (rank : 28)
Query Neighborhood Hits	44	Target Neighborhood Hits	325	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

TTC4_MOUSE
θ value	1.81305 (rank : 23)	NC score	0.019612 (rank : 33)
Query Neighborhood Hits	44	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R3H9	Gene names	Ttc4
Domain Architecture
Description	Tetratricopeptide repeat protein 4 (TPR repeat protein 4).

LRSM1_HUMAN
θ value	2.36792 (rank : 24)	NC score	0.007125 (rank : 43)
Query Neighborhood Hits	44	Target Neighborhood Hits	1078	Shared Neighborhood Hits	7
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

COPG_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.032485 (rank : 23)
Query Neighborhood Hits	44	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y678	Gene names	COPG
Domain Architecture
Description	Coatomer subunit gamma (Gamma-coat protein) (Gamma-COP).

ERR2_MOUSE
θ value	3.0926 (rank : 26)	NC score	0.004928 (rank : 44)
Query Neighborhood Hits	44	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

SIX4_HUMAN
θ value	3.0926 (rank : 27)	NC score	0.018519 (rank : 35)
Query Neighborhood Hits	44	Target Neighborhood Hits	342	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UIU6	Gene names	SIX4
Domain Architecture
Description	Homeobox protein SIX4 (Sine oculis homeobox homolog 4).

TNPO2_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.064266 (rank : 16)
Query Neighborhood Hits	44	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_MOUSE
θ value	3.0926 (rank : 29)	NC score	0.064772 (rank : 15)
Query Neighborhood Hits	44	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

UBR2_HUMAN
θ value	3.0926 (rank : 30)	NC score	0.022506 (rank : 27)
Query Neighborhood Hits	44	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWV8, O15057, Q4VXK2, Q5TFH6, Q6P2I2, Q6ZUD0	Gene names	UBR2, C6orf133, KIAA0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

CE110_HUMAN
θ value	4.03905 (rank : 31)	NC score	0.032792 (rank : 22)
Query Neighborhood Hits	44	Target Neighborhood Hits	197	Shared Neighborhood Hits	5
SwissProt Accessions	O43303, O43335, Q68DV9, Q8NE13	Gene names	CEP110, CP110, KIAA0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

SPAG5_HUMAN
θ value	4.03905 (rank : 32)	NC score	0.009790 (rank : 41)
Query Neighborhood Hits	44	Target Neighborhood Hits	625	Shared Neighborhood Hits	6
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

UTP20_HUMAN
θ value	4.03905 (rank : 33)	NC score	0.018792 (rank : 34)
Query Neighborhood Hits	44	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

ZN184_HUMAN
θ value	4.03905 (rank : 34)	NC score	-0.000910 (rank : 47)
Query Neighborhood Hits	44	Target Neighborhood Hits	811	Shared Neighborhood Hits	2
SwissProt Accessions	Q99676, O60792, Q8TBA9	Gene names	ZNF184
Domain Architecture
Description	Zinc finger protein 184.

ADO_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.010459 (rank : 40)
Query Neighborhood Hits	44	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	O54754, Q9WU85, Q9Z2Z5	Gene names	Aox1, Ao, Ro
Domain Architecture
Description	Aldehyde oxidase (EC 1.2.3.1) (Retinal oxidase).

COPG2_HUMAN
θ value	5.27518 (rank : 36)	NC score	0.028312 (rank : 25)
Query Neighborhood Hits	44	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBF2	Gene names	COPG2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

HD_MOUSE
θ value	5.27518 (rank : 37)	NC score	0.021005 (rank : 31)
Query Neighborhood Hits	44	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

HEAT3_MOUSE
θ value	5.27518 (rank : 38)	NC score	0.015049 (rank : 39)
Query Neighborhood Hits	44	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BQM4, Q8C731	Gene names	Heatr3
Domain Architecture
Description	HEAT repeat-containing protein 3.

COPG2_MOUSE
θ value	6.88961 (rank : 39)	NC score	0.026438 (rank : 26)
Query Neighborhood Hits	44	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXK3	Gene names	Copg2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

CP135_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.003352 (rank : 45)
Query Neighborhood Hits	44	Target Neighborhood Hits	1290	Shared Neighborhood Hits	8
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

HD_HUMAN
θ value	6.88961 (rank : 41)	NC score	0.019684 (rank : 32)
Query Neighborhood Hits	44	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

SYMPK_HUMAN
θ value	6.88961 (rank : 42)	NC score	0.017019 (rank : 37)
Query Neighborhood Hits	44	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q92797, O00521, O00689, O00733, Q59GT5, Q8N2U5	Gene names	SYMPK, SPK
Domain Architecture	No domain graphic available
Description	Symplekin.

SYMPK_MOUSE
θ value	6.88961 (rank : 43)	NC score	0.016919 (rank : 38)
Query Neighborhood Hits	44	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	Q80X82	Gene names	Sympk
Domain Architecture	No domain graphic available
Description	Symplekin.

SMG5_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.008340 (rank : 42)
Query Neighborhood Hits	44	Target Neighborhood Hits	180	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

CLAP2_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.058338 (rank : 20)
Query Neighborhood Hits	44	Target Neighborhood Hits	85	Shared Neighborhood Hits	6
SwissProt Accessions	O75122, Q7L8F6, Q8N6R6, Q9BQT3, Q9BQT4, Q9H7A3, Q9NSZ2	Gene names	CLASP2, KIAA0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

CLAP2_MOUSE
θ value	θ > 10 (rank : 46)	NC score	0.058605 (rank : 19)
Query Neighborhood Hits	44	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BRT1, Q8CHE3, Q99JI3, Q9DB80	Gene names	Clasp2, Kiaa0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

RNBP6_HUMAN
θ value	θ > 10 (rank : 47)	NC score	0.070139 (rank : 14)
Query Neighborhood Hits	44	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	O60518, Q5T7X4, Q7Z3V2, Q96E78	Gene names	RANBP6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 6 (RanBP6).

Hits sorted by NC score

CAND2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

CAND2_HUMAN
NC score	0.992498 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	44	Target Neighborhood Hits	40	Shared Neighborhood Hits	22
SwissProt Accessions	O75155	Gene names	CAND2, KIAA0667
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2).

CAND1_HUMAN
NC score	0.981598 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	44	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	Q86VP6, O94918, Q6PIY4, Q8NDJ4, Q96JZ9, Q96T19, Q9BTC4, Q9H0G2, Q9P0H7, Q9UF85	Gene names	CAND1, KIAA0829, TIP120, TIP120A
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1) (TBP-interacting protein TIP120A) (TBP-interacting protein of 120 kDa A).

CAND1_MOUSE
NC score	0.981032 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	44	Target Neighborhood Hits	42	Shared Neighborhood Hits	10
SwissProt Accessions	Q6ZQ38, Q6PFR0, Q9CV45	Gene names	Cand1, D10Ertd516e, Kiaa0829
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1).

IPO4_HUMAN
NC score	0.210715 (rank : 5)	θ value	5.81887e-07 (rank : 5)
Query Neighborhood Hits	44	Target Neighborhood Hits	49	Shared Neighborhood Hits	17
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

IPO4_MOUSE
NC score	0.172001 (rank : 6)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VI75, Q3TBW0, Q99J52	Gene names	Ipo4, Imp4a, Ranbp4
Domain Architecture	No domain graphic available
Description	Importin-4 (Importin 4a) (Imp4a) (Ran-binding protein 4) (RanBP4).

GCN1L_HUMAN
NC score	0.162424 (rank : 7)	θ value	0.0330416 (rank : 10)
Query Neighborhood Hits	44	Target Neighborhood Hits	112	Shared Neighborhood Hits	20
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

IMB3_HUMAN
NC score	0.116679 (rank : 8)	θ value	0.00665767 (rank : 6)
Query Neighborhood Hits	44	Target Neighborhood Hits	57	Shared Neighborhood Hits	14
SwissProt Accessions	O00410, O15257	Gene names	RANBP5, KPNB3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

IMB3_MOUSE
NC score	0.112034 (rank : 9)	θ value	0.0148317 (rank : 7)
Query Neighborhood Hits	44	Target Neighborhood Hits	58	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BKC5, Q3TEG2, Q7TQC6, Q9EQ30	Gene names	Ranbp5, Kpnb3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

2AAA_HUMAN
NC score	0.082865 (rank : 10)	θ value	0.0252991 (rank : 8)
Query Neighborhood Hits	44	Target Neighborhood Hits	42	Shared Neighborhood Hits	12
SwissProt Accessions	P30153, Q13773	Gene names	PPP2R1A
Domain Architecture
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor antigen-associated 61 kDa protein).

2AAA_MOUSE
NC score	0.081100 (rank : 11)	θ value	0.0252991 (rank : 9)
Query Neighborhood Hits	44	Target Neighborhood Hits	41	Shared Neighborhood Hits	12
SwissProt Accessions	Q76MZ3	Gene names	Ppp2r1a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform).

FRAP_MOUSE
NC score	0.074087 (rank : 12)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	44	Target Neighborhood Hits	77	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_HUMAN
NC score	0.073820 (rank : 13)	θ value	0.813845 (rank : 12)
Query Neighborhood Hits	44	Target Neighborhood Hits	83	Shared Neighborhood Hits	13
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

RNBP6_HUMAN
NC score	0.070139 (rank : 14)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	44	Target Neighborhood Hits	31	Shared Neighborhood Hits	9
SwissProt Accessions	O60518, Q5T7X4, Q7Z3V2, Q96E78	Gene names	RANBP6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 6 (RanBP6).

TNPO2_MOUSE
NC score	0.064772 (rank : 15)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	44	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_HUMAN
NC score	0.064266 (rank : 16)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	44	Target Neighborhood Hits	47	Shared Neighborhood Hits	14
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO1_MOUSE
NC score	0.061665 (rank : 17)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	44	Target Neighborhood Hits	63	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

TNPO1_HUMAN
NC score	0.061653 (rank : 18)	θ value	1.06291 (rank : 15)
Query Neighborhood Hits	44	Target Neighborhood Hits	64	Shared Neighborhood Hits	15
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

CLAP2_MOUSE
NC score	0.058605 (rank : 19)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	44	Target Neighborhood Hits	88	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BRT1, Q8CHE3, Q99JI3, Q9DB80	Gene names	Clasp2, Kiaa0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

CLAP2_HUMAN
NC score	0.058338 (rank : 20)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	44	Target Neighborhood Hits	85	Shared Neighborhood Hits	6
SwissProt Accessions	O75122, Q7L8F6, Q8N6R6, Q9BQT3, Q9BQT4, Q9H7A3, Q9NSZ2	Gene names	CLASP2, KIAA0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

CE110_MOUSE
NC score	0.046204 (rank : 21)	θ value	0.21417 (rank : 11)
Query Neighborhood Hits	44	Target Neighborhood Hits	170	Shared Neighborhood Hits	6
SwissProt Accessions	Q7TSH4, Q6A072	Gene names	Cep110, Cp110, Kiaa0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

CE110_HUMAN
NC score	0.032792 (rank : 22)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	44	Target Neighborhood Hits	197	Shared Neighborhood Hits	5
SwissProt Accessions	O43303, O43335, Q68DV9, Q8NE13	Gene names	CEP110, CP110, KIAA0419
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 110 kDa (Cep110 protein).

COPG_HUMAN
NC score	0.032485 (rank : 23)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	44	Target Neighborhood Hits	31	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y678	Gene names	COPG
Domain Architecture
Description	Coatomer subunit gamma (Gamma-coat protein) (Gamma-COP).

UBR2_MOUSE
NC score	0.028687 (rank : 24)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	44	Target Neighborhood Hits	37	Shared Neighborhood Hits	4
SwissProt Accessions	Q6WKZ8, Q6DIB9, Q80U31, Q8BUL9, Q8CGW0, Q8K2I6, Q8R0V7, Q8R130	Gene names	Ubr2, Kiaa0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

COPG2_HUMAN
NC score	0.028312 (rank : 25)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	44	Target Neighborhood Hits	33	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UBF2	Gene names	COPG2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

COPG2_MOUSE
NC score	0.026438 (rank : 26)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	44	Target Neighborhood Hits	32	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QXK3	Gene names	Copg2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

UBR2_HUMAN
NC score	0.022506 (rank : 27)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	44	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWV8, O15057, Q4VXK2, Q5TFH6, Q6P2I2, Q6ZUD0	Gene names	UBR2, C6orf133, KIAA0349
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase E3 component N-recognin-2 (EC 6.-.-.-) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3- alpha-II).

SFR17_HUMAN
NC score	0.022454 (rank : 28)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	44	Target Neighborhood Hits	325	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

AP2A2_HUMAN
NC score	0.021412 (rank : 29)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	44	Target Neighborhood Hits	39	Shared Neighborhood Hits	3
SwissProt Accessions	O94973, O75403, Q96SI8	Gene names	AP2A2, ADTAB, KIAA0899
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) (Huntingtin-interacting protein HYPJ).

AP2A2_MOUSE
NC score	0.021382 (rank : 30)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	44	Target Neighborhood Hits	46	Shared Neighborhood Hits	3
SwissProt Accessions	P17427, Q921V0	Gene names	Ap2a2, Adtab
Domain Architecture
Description	AP-2 complex subunit alpha-2 (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha-adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit).

HD_MOUSE
NC score	0.021005 (rank : 31)	θ value	5.27518 (rank : 37)
Query Neighborhood Hits	44	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	P42859	Gene names	Hd, Hdh
Domain Architecture
Description	Huntingtin (Huntington disease protein homolog) (HD protein).

HD_HUMAN
NC score	0.019684 (rank : 32)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	44	Target Neighborhood Hits	165	Shared Neighborhood Hits	6
SwissProt Accessions	P42858, Q9UQB7	Gene names	HD, IT15
Domain Architecture
Description	Huntingtin (Huntington disease protein) (HD protein).

TTC4_MOUSE
NC score	0.019612 (rank : 33)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	44	Target Neighborhood Hits	85	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R3H9	Gene names	Ttc4
Domain Architecture
Description	Tetratricopeptide repeat protein 4 (TPR repeat protein 4).

UTP20_HUMAN
NC score	0.018792 (rank : 34)	θ value	4.03905 (rank : 33)
Query Neighborhood Hits	44	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	O75691, Q9H3H4	Gene names	UTP20, DRIM
Domain Architecture	No domain graphic available
Description	Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Protein Key-1A6) (Novel nucleolar protein 73) (NNP73).

SIX4_HUMAN
NC score	0.018519 (rank : 35)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	44	Target Neighborhood Hits	342	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UIU6	Gene names	SIX4
Domain Architecture
Description	Homeobox protein SIX4 (Sine oculis homeobox homolog 4).

EFG1_HUMAN
NC score	0.017727 (rank : 36)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	44	Target Neighborhood Hits	34	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RP9, Q96T39	Gene names	GFM1, EFG, EFG1, GFM
Domain Architecture
Description	Elongation factor G 1, mitochondrial precursor (mEF-G 1) (Elongation factor G1).

SYMPK_HUMAN
NC score	0.017019 (rank : 37)	θ value	6.88961 (rank : 42)
Query Neighborhood Hits	44	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q92797, O00521, O00689, O00733, Q59GT5, Q8N2U5	Gene names	SYMPK, SPK
Domain Architecture	No domain graphic available
Description	Symplekin.

SYMPK_MOUSE
NC score	0.016919 (rank : 38)	θ value	6.88961 (rank : 43)
Query Neighborhood Hits	44	Target Neighborhood Hits	109	Shared Neighborhood Hits	3
SwissProt Accessions	Q80X82	Gene names	Sympk
Domain Architecture	No domain graphic available
Description	Symplekin.

HEAT3_MOUSE
NC score	0.015049 (rank : 39)	θ value	5.27518 (rank : 38)
Query Neighborhood Hits	44	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BQM4, Q8C731	Gene names	Heatr3
Domain Architecture
Description	HEAT repeat-containing protein 3.

ADO_MOUSE
NC score	0.010459 (rank : 40)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	44	Target Neighborhood Hits	23	Shared Neighborhood Hits	2
SwissProt Accessions	O54754, Q9WU85, Q9Z2Z5	Gene names	Aox1, Ao, Ro
Domain Architecture
Description	Aldehyde oxidase (EC 1.2.3.1) (Retinal oxidase).

SPAG5_HUMAN
NC score	0.009790 (rank : 41)	θ value	4.03905 (rank : 32)
Query Neighborhood Hits	44	Target Neighborhood Hits	625	Shared Neighborhood Hits	6
SwissProt Accessions	Q96R06, O95213, Q9BWE8, Q9NT17, Q9UFE6	Gene names	SPAG5
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 5 (Astrin) (Mitotic spindle-associated protein p126) (MAP126) (Deepest).

SMG5_HUMAN
NC score	0.008340 (rank : 42)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	44	Target Neighborhood Hits	180	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPR3, Q5QJE7, Q8IXC0, Q8IY09, Q96IJ7	Gene names	SMG5, EST1B, KIAA1089
Domain Architecture	No domain graphic available
Description	Protein SMG5 (SMG-5 homolog) (EST1-like protein B) (LPTS-interacting protein) (LPTS-RP1).

LRSM1_HUMAN
NC score	0.007125 (rank : 43)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	44	Target Neighborhood Hits	1078	Shared Neighborhood Hits	7
SwissProt Accessions	Q6UWE0, Q5VVV0, Q8NB40, Q96GT5, Q96MX5, Q96MZ7	Gene names	LRSAM1, TAL
Domain Architecture	No domain graphic available
Description	Ubiquitin ligase protein LRSAM1 (EC 6.3.2.-) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (Tsg101-associated ligase) (hTAL).

ERR2_MOUSE
NC score	0.004928 (rank : 44)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	44	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

CP135_HUMAN
NC score	0.003352 (rank : 45)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	44	Target Neighborhood Hits	1290	Shared Neighborhood Hits	8
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

MYH3_HUMAN
NC score	0.003201 (rank : 46)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	44	Target Neighborhood Hits	1660	Shared Neighborhood Hits	7
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

ZN184_HUMAN
NC score	-0.000910 (rank : 47)	θ value	4.03905 (rank : 34)
Query Neighborhood Hits	44	Target Neighborhood Hits	811	Shared Neighborhood Hits	2
SwissProt Accessions	Q99676, O60792, Q8TBA9	Gene names	ZNF184
Domain Architecture
Description	Zinc finger protein 184.