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Network neighborhood for query Sequence : IPO4_MOUSE

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IPO4_MOUSE
SwissProt Accessions	Q8VI75, Q3TBW0, Q99J52	Gene names	Ipo4, Imp4a, Ranbp4
Domain Architecture	No domain graphic available
Description	Importin-4 (Importin 4a) (Imp4a) (Ran-binding protein 4) (RanBP4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IPO4_HUMAN
θ value	0 (rank : 1)	NC score	0.984000 (rank : 2)
Query Neighborhood Hits	44	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

IPO4_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VI75, Q3TBW0, Q99J52	Gene names	Ipo4, Imp4a, Ranbp4
Domain Architecture	No domain graphic available
Description	Importin-4 (Importin 4a) (Imp4a) (Ran-binding protein 4) (RanBP4).

IMB3_HUMAN
θ value	1.62093e-41 (rank : 3)	NC score	0.720866 (rank : 3)
Query Neighborhood Hits	44	Target Neighborhood Hits	57	Shared Neighborhood Hits	21
SwissProt Accessions	O00410, O15257	Gene names	RANBP5, KPNB3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

IMB3_MOUSE
θ value	8.04462e-41 (rank : 4)	NC score	0.719554 (rank : 4)
Query Neighborhood Hits	44	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BKC5, Q3TEG2, Q7TQC6, Q9EQ30	Gene names	Ranbp5, Kpnb3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

RNBP6_HUMAN
θ value	4.27553e-34 (rank : 5)	NC score	0.701681 (rank : 5)
Query Neighborhood Hits	44	Target Neighborhood Hits	31	Shared Neighborhood Hits	15
SwissProt Accessions	O60518, Q5T7X4, Q7Z3V2, Q96E78	Gene names	RANBP6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 6 (RanBP6).

TNPO2_HUMAN
θ value	4.1701e-05 (rank : 6)	NC score	0.332499 (rank : 8)
Query Neighborhood Hits	44	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

IPO11_MOUSE
θ value	7.1131e-05 (rank : 7)	NC score	0.181781 (rank : 14)
Query Neighborhood Hits	44	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K2V6, Q8BU45, Q8K0B4	Gene names	Ipo11, Ranbp11
Domain Architecture	No domain graphic available
Description	Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11).

CAND2_HUMAN
θ value	9.29e-05 (rank : 8)	NC score	0.195599 (rank : 12)
Query Neighborhood Hits	44	Target Neighborhood Hits	40	Shared Neighborhood Hits	22
SwissProt Accessions	O75155	Gene names	CAND2, KIAA0667
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2).

TNPO2_MOUSE
θ value	9.29e-05 (rank : 9)	NC score	0.330747 (rank : 9)
Query Neighborhood Hits	44	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

IMB1_MOUSE
θ value	0.000121331 (rank : 10)	NC score	0.309640 (rank : 11)
Query Neighborhood Hits	44	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

IPO11_HUMAN
θ value	0.000121331 (rank : 11)	NC score	0.179839 (rank : 15)
Query Neighborhood Hits	44	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UI26, Q8N5R2, Q9NSJ6, Q9NVB1	Gene names	IPO11, RANBP11
Domain Architecture	No domain graphic available
Description	Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11).

TNPO1_HUMAN
θ value	0.000121331 (rank : 12)	NC score	0.335735 (rank : 6)
Query Neighborhood Hits	44	Target Neighborhood Hits	64	Shared Neighborhood Hits	26
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

IMB1_HUMAN
θ value	0.00020696 (rank : 13)	NC score	0.315429 (rank : 10)
Query Neighborhood Hits	44	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

TNPO1_MOUSE
θ value	0.00020696 (rank : 14)	NC score	0.333251 (rank : 7)
Query Neighborhood Hits	44	Target Neighborhood Hits	63	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

GCN1L_HUMAN
θ value	0.00298849 (rank : 15)	NC score	0.192243 (rank : 13)
Query Neighborhood Hits	44	Target Neighborhood Hits	112	Shared Neighborhood Hits	23
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

FRAP_HUMAN
θ value	0.00869519 (rank : 16)	NC score	0.126034 (rank : 18)
Query Neighborhood Hits	44	Target Neighborhood Hits	83	Shared Neighborhood Hits	16
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

FRAP_MOUSE
θ value	0.0113563 (rank : 17)	NC score	0.124277 (rank : 20)
Query Neighborhood Hits	44	Target Neighborhood Hits	77	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

CAND1_MOUSE
θ value	0.125558 (rank : 18)	NC score	0.119869 (rank : 22)
Query Neighborhood Hits	44	Target Neighborhood Hits	42	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZQ38, Q6PFR0, Q9CV45	Gene names	Cand1, D10Ertd516e, Kiaa0829
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1).

CAND1_HUMAN
θ value	0.163984 (rank : 19)	NC score	0.129840 (rank : 17)
Query Neighborhood Hits	44	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q86VP6, O94918, Q6PIY4, Q8NDJ4, Q96JZ9, Q96T19, Q9BTC4, Q9H0G2, Q9P0H7, Q9UF85	Gene names	CAND1, KIAA0829, TIP120, TIP120A
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1) (TBP-interacting protein TIP120A) (TBP-interacting protein of 120 kDa A).

CLAP1_HUMAN
θ value	0.163984 (rank : 20)	NC score	0.092152 (rank : 26)
Query Neighborhood Hits	44	Target Neighborhood Hits	70	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z460, O75118, Q8N5B8, Q9BQT5	Gene names	CLASP1, KIAA0622, MAST1
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1).

TRRAP_HUMAN
θ value	0.21417 (rank : 21)	NC score	0.059061 (rank : 31)
Query Neighborhood Hits	44	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

IPO9_HUMAN
θ value	0.365318 (rank : 22)	NC score	0.125431 (rank : 19)
Query Neighborhood Hits	44	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q96P70, Q8N1Y1, Q8N3I2, Q8NCG9, Q96SU6, Q9NW01, Q9P0A8, Q9ULM8	Gene names	IPO9, IMP9, KIAA1192, RANBP9
Domain Architecture
Description	Importin-9 (Imp9) (Ran-binding protein 9) (RanbP9).

CLAP2_MOUSE
θ value	0.47712 (rank : 23)	NC score	0.096806 (rank : 23)
Query Neighborhood Hits	44	Target Neighborhood Hits	88	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BRT1, Q8CHE3, Q99JI3, Q9DB80	Gene names	Clasp2, Kiaa0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

ECM29_HUMAN
θ value	0.47712 (rank : 24)	NC score	0.095172 (rank : 24)
Query Neighborhood Hits	44	Target Neighborhood Hits	46	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VYK3, O15074, Q8WU82	Gene names	ECM29, KIAA0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

IPO9_MOUSE
θ value	0.47712 (rank : 25)	NC score	0.124013 (rank : 21)
Query Neighborhood Hits	44	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q91YE6, Q924M3, Q924M4	Gene names	Ipo9, Imp9, Ranbp9
Domain Architecture
Description	Importin-9 (Importin 9a) (Imp9a) (Importin 9b) (Imp9b) (Ran-binding protein 9) (RanBP9).

CLAP2_HUMAN
θ value	0.62314 (rank : 26)	NC score	0.094023 (rank : 25)
Query Neighborhood Hits	44	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	O75122, Q7L8F6, Q8N6R6, Q9BQT3, Q9BQT4, Q9H7A3, Q9NSZ2	Gene names	CLASP2, KIAA0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

CAND2_MOUSE
θ value	1.06291 (rank : 27)	NC score	0.172001 (rank : 16)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

IMA2_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.016441 (rank : 40)
Query Neighborhood Hits	44	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

PSMD5_MOUSE
θ value	2.36792 (rank : 29)	NC score	0.029149 (rank : 33)
Query Neighborhood Hits	44	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJY1, Q3UFV2, Q8BMA9, Q8VEE9	Gene names	Psmd5
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 5 (26S proteasome subunit S5B) (26S protease subunit S5 basic).

SF3B1_HUMAN
θ value	2.36792 (rank : 30)	NC score	0.059892 (rank : 30)
Query Neighborhood Hits	44	Target Neighborhood Hits	341	Shared Neighborhood Hits	15
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

XPO2_HUMAN
θ value	2.36792 (rank : 31)	NC score	0.084722 (rank : 27)
Query Neighborhood Hits	44	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	P55060, O75432, Q32M40, Q9H5B7, Q9NTS0, Q9UP98, Q9UP99, Q9UPA0	Gene names	CSE1L, CAS, XPO2
Domain Architecture
Description	Exportin-2 (Exp2) (Importin-alpha re-exporter) (Chromosome segregation 1-like protein) (Cellular apoptosis susceptibility protein).

C10_HUMAN
θ value	5.27518 (rank : 32)	NC score	0.025116 (rank : 34)
Query Neighborhood Hits	44	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q99622	Gene names	C12orf57, C10
Domain Architecture	No domain graphic available
Description	Putative C10 protein.

ECM29_MOUSE
θ value	5.27518 (rank : 33)	NC score	0.067272 (rank : 29)
Query Neighborhood Hits	44	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PDI5, Q6ZQC9, Q8BSW7, Q8CAH0, Q8R3M6	Gene names	Ecm29, Kiaa0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

FBX4_MOUSE
θ value	5.27518 (rank : 34)	NC score	0.018651 (rank : 36)
Query Neighborhood Hits	44	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CHQ0, Q99JG8	Gene names	Fbxo4, Fbx4
Domain Architecture	No domain graphic available
Description	F-box only protein 4.

SF3B1_MOUSE
θ value	5.27518 (rank : 35)	NC score	0.058316 (rank : 32)
Query Neighborhood Hits	44	Target Neighborhood Hits	352	Shared Neighborhood Hits	16
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

HEAT1_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.023208 (rank : 35)
Query Neighborhood Hits	44	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H583, Q5T3Q8, Q9NW23	Gene names	HEATR1, BAP28
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 1 (Protein BAP28).

SCYL2_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.017253 (rank : 38)
Query Neighborhood Hits	44	Target Neighborhood Hits	632	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P3W7, Q96EF4, Q96ST4, Q9H7V5, Q9NVH3, Q9P2I7	Gene names	SCYL2, CVAK104, KIAA1360
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

SCYL2_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.017743 (rank : 37)
Query Neighborhood Hits	44	Target Neighborhood Hits	603	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CFE4, Q3UT57, Q3UWU9, Q8K0M4	Gene names	Scyl2, Cvak104, D10Ertd802e
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

STAU1_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.011979 (rank : 41)
Query Neighborhood Hits	44	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	O95793, Q6GTM4, Q9H5B4, Q9H5B5, Q9Y3Q2	Gene names	STAU1, STAU
Domain Architecture
Description	Double-stranded RNA-binding protein Staufen homolog 1.

XPO2_MOUSE
θ value	6.88961 (rank : 40)	NC score	0.071970 (rank : 28)
Query Neighborhood Hits	44	Target Neighborhood Hits	27	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ERK4	Gene names	Cse1l, Xpo2
Domain Architecture
Description	Exportin-2 (Exp2) (Importin-alpha re-exporter) (Chromosome segregation 1-like protein).

AP2B1_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.009213 (rank : 43)
Query Neighborhood Hits	44	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	P63010, P21851, Q96J19	Gene names	AP2B1, CLAPB1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

AP2B1_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.009214 (rank : 42)
Query Neighborhood Hits	44	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBG3, Q80XJ4	Gene names	Ap2b1, Clapb1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

DYH5_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.006298 (rank : 44)
Query Neighborhood Hits	44	Target Neighborhood Hits	323	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).

K0423_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.016902 (rank : 39)
Query Neighborhood Hits	44	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

Hits sorted by NC score

IPO4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	44
SwissProt Accessions	Q8VI75, Q3TBW0, Q99J52	Gene names	Ipo4, Imp4a, Ranbp4
Domain Architecture	No domain graphic available
Description	Importin-4 (Importin 4a) (Imp4a) (Ran-binding protein 4) (RanBP4).

IPO4_HUMAN
NC score	0.984000 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	44	Target Neighborhood Hits	49	Shared Neighborhood Hits	28
SwissProt Accessions	Q8TEX9, Q86TZ9, Q8NCG8, Q96SJ3, Q9BTI4, Q9H5L0	Gene names	IPO4, IMP4B, RANBP4
Domain Architecture
Description	Importin-4 (Importin 4b) (Imp4b) (Ran-binding protein 4) (RanBP4).

IMB3_HUMAN
NC score	0.720866 (rank : 3)	θ value	1.62093e-41 (rank : 3)
Query Neighborhood Hits	44	Target Neighborhood Hits	57	Shared Neighborhood Hits	21
SwissProt Accessions	O00410, O15257	Gene names	RANBP5, KPNB3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

IMB3_MOUSE
NC score	0.719554 (rank : 4)	θ value	8.04462e-41 (rank : 4)
Query Neighborhood Hits	44	Target Neighborhood Hits	58	Shared Neighborhood Hits	21
SwissProt Accessions	Q8BKC5, Q3TEG2, Q7TQC6, Q9EQ30	Gene names	Ranbp5, Kpnb3
Domain Architecture
Description	Importin beta-3 (Karyopherin beta-3) (Ran-binding protein 5) (RanBP5).

RNBP6_HUMAN
NC score	0.701681 (rank : 5)	θ value	4.27553e-34 (rank : 5)
Query Neighborhood Hits	44	Target Neighborhood Hits	31	Shared Neighborhood Hits	15
SwissProt Accessions	O60518, Q5T7X4, Q7Z3V2, Q96E78	Gene names	RANBP6
Domain Architecture	No domain graphic available
Description	Ran-binding protein 6 (RanBP6).

TNPO1_HUMAN
NC score	0.335735 (rank : 6)	θ value	0.000121331 (rank : 12)
Query Neighborhood Hits	44	Target Neighborhood Hits	64	Shared Neighborhood Hits	26
SwissProt Accessions	Q92973, Q92957, Q92975	Gene names	TNPO1, KPNB2, MIP1, TRN
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP).

TNPO1_MOUSE
NC score	0.333251 (rank : 7)	θ value	0.00020696 (rank : 14)
Query Neighborhood Hits	44	Target Neighborhood Hits	63	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BFY9, Q8C0S3, Q8K2E7	Gene names	Tnpo1, Kpnb2
Domain Architecture
Description	Transportin-1 (Importin beta-2) (Karyopherin beta-2).

TNPO2_HUMAN
NC score	0.332499 (rank : 8)	θ value	4.1701e-05 (rank : 6)
Query Neighborhood Hits	44	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	O14787, O14655	Gene names	TNPO2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

TNPO2_MOUSE
NC score	0.330747 (rank : 9)	θ value	9.29e-05 (rank : 9)
Query Neighborhood Hits	44	Target Neighborhood Hits	47	Shared Neighborhood Hits	25
SwissProt Accessions	Q99LG2, Q8C0U9	Gene names	Tnpo2
Domain Architecture
Description	Transportin-2 (Karyopherin beta-2b).

IMB1_HUMAN
NC score	0.315429 (rank : 10)	θ value	0.00020696 (rank : 13)
Query Neighborhood Hits	44	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	Q14974, Q14637, Q96J27	Gene names	KPNB1, NTF97
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Importin 90).

IMB1_MOUSE
NC score	0.309640 (rank : 11)	θ value	0.000121331 (rank : 10)
Query Neighborhood Hits	44	Target Neighborhood Hits	51	Shared Neighborhood Hits	19
SwissProt Accessions	P70168, Q62117	Gene names	Kpnb1, Impnb
Domain Architecture
Description	Importin beta-1 subunit (Karyopherin beta-1 subunit) (Nuclear factor P97) (Pore targeting complex 97 kDa subunit) (PTAC97) (SCG).

CAND2_HUMAN
NC score	0.195599 (rank : 12)	θ value	9.29e-05 (rank : 8)
Query Neighborhood Hits	44	Target Neighborhood Hits	40	Shared Neighborhood Hits	22
SwissProt Accessions	O75155	Gene names	CAND2, KIAA0667
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2).

GCN1L_HUMAN
NC score	0.192243 (rank : 13)	θ value	0.00298849 (rank : 15)
Query Neighborhood Hits	44	Target Neighborhood Hits	112	Shared Neighborhood Hits	23
SwissProt Accessions	Q92616, O95001, O95651, Q6P2S3, Q86X65, Q8N5I5, Q8WU80, Q99736, Q9UE60	Gene names	GCN1L1, KIAA0219
Domain Architecture	No domain graphic available
Description	GCN1-like protein 1 (HsGCN1).

IPO11_MOUSE
NC score	0.181781 (rank : 14)	θ value	7.1131e-05 (rank : 7)
Query Neighborhood Hits	44	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K2V6, Q8BU45, Q8K0B4	Gene names	Ipo11, Ranbp11
Domain Architecture	No domain graphic available
Description	Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11).

IPO11_HUMAN
NC score	0.179839 (rank : 15)	θ value	0.000121331 (rank : 11)
Query Neighborhood Hits	44	Target Neighborhood Hits	32	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UI26, Q8N5R2, Q9NSJ6, Q9NVB1	Gene names	IPO11, RANBP11
Domain Architecture	No domain graphic available
Description	Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11).

CAND2_MOUSE
NC score	0.172001 (rank : 16)	θ value	1.06291 (rank : 27)
Query Neighborhood Hits	44	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	Q6ZQ73, Q6PHT7	Gene names	Cand2, Kiaa0667, Tip120b
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (p120 CAND2) (TBP-interacting protein TIP120B) (TBP-interacting protein of 120 kDa B).

CAND1_HUMAN
NC score	0.129840 (rank : 17)	θ value	0.163984 (rank : 19)
Query Neighborhood Hits	44	Target Neighborhood Hits	45	Shared Neighborhood Hits	22
SwissProt Accessions	Q86VP6, O94918, Q6PIY4, Q8NDJ4, Q96JZ9, Q96T19, Q9BTC4, Q9H0G2, Q9P0H7, Q9UF85	Gene names	CAND1, KIAA0829, TIP120, TIP120A
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1) (TBP-interacting protein TIP120A) (TBP-interacting protein of 120 kDa A).

FRAP_HUMAN
NC score	0.126034 (rank : 18)	θ value	0.00869519 (rank : 16)
Query Neighborhood Hits	44	Target Neighborhood Hits	83	Shared Neighborhood Hits	16
SwissProt Accessions	P42345, Q6LE87, Q96QG3, Q9Y4I3	Gene names	FRAP1, FRAP, FRAP2
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

IPO9_HUMAN
NC score	0.125431 (rank : 19)	θ value	0.365318 (rank : 22)
Query Neighborhood Hits	44	Target Neighborhood Hits	28	Shared Neighborhood Hits	12
SwissProt Accessions	Q96P70, Q8N1Y1, Q8N3I2, Q8NCG9, Q96SU6, Q9NW01, Q9P0A8, Q9ULM8	Gene names	IPO9, IMP9, KIAA1192, RANBP9
Domain Architecture
Description	Importin-9 (Imp9) (Ran-binding protein 9) (RanbP9).

FRAP_MOUSE
NC score	0.124277 (rank : 20)	θ value	0.0113563 (rank : 17)
Query Neighborhood Hits	44	Target Neighborhood Hits	77	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JLN9, Q811J5, Q9CST1	Gene names	Frap1, Frap
Domain Architecture
Description	FKBP12-rapamycin complex-associated protein (FK506-binding protein 12- rapamycin complex-associated protein 1) (Rapamycin target protein) (RAPT1) (Mammalian target of rapamycin) (mTOR).

IPO9_MOUSE
NC score	0.124013 (rank : 21)	θ value	0.47712 (rank : 25)
Query Neighborhood Hits	44	Target Neighborhood Hits	26	Shared Neighborhood Hits	12
SwissProt Accessions	Q91YE6, Q924M3, Q924M4	Gene names	Ipo9, Imp9, Ranbp9
Domain Architecture
Description	Importin-9 (Importin 9a) (Imp9a) (Importin 9b) (Imp9b) (Ran-binding protein 9) (RanBP9).

CAND1_MOUSE
NC score	0.119869 (rank : 22)	θ value	0.125558 (rank : 18)
Query Neighborhood Hits	44	Target Neighborhood Hits	42	Shared Neighborhood Hits	18
SwissProt Accessions	Q6ZQ38, Q6PFR0, Q9CV45	Gene names	Cand1, D10Ertd516e, Kiaa0829
Domain Architecture	No domain graphic available
Description	Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (p120 CAND1).

CLAP2_MOUSE
NC score	0.096806 (rank : 23)	θ value	0.47712 (rank : 23)
Query Neighborhood Hits	44	Target Neighborhood Hits	88	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BRT1, Q8CHE3, Q99JI3, Q9DB80	Gene names	Clasp2, Kiaa0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

ECM29_HUMAN
NC score	0.095172 (rank : 24)	θ value	0.47712 (rank : 24)
Query Neighborhood Hits	44	Target Neighborhood Hits	46	Shared Neighborhood Hits	14
SwissProt Accessions	Q5VYK3, O15074, Q8WU82	Gene names	ECM29, KIAA0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

CLAP2_HUMAN
NC score	0.094023 (rank : 25)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	44	Target Neighborhood Hits	85	Shared Neighborhood Hits	8
SwissProt Accessions	O75122, Q7L8F6, Q8N6R6, Q9BQT3, Q9BQT4, Q9H7A3, Q9NSZ2	Gene names	CLASP2, KIAA0627
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2).

CLAP1_HUMAN
NC score	0.092152 (rank : 26)	θ value	0.163984 (rank : 20)
Query Neighborhood Hits	44	Target Neighborhood Hits	70	Shared Neighborhood Hits	9
SwissProt Accessions	Q7Z460, O75118, Q8N5B8, Q9BQT5	Gene names	CLASP1, KIAA0622, MAST1
Domain Architecture	No domain graphic available
Description	CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1).

XPO2_HUMAN
NC score	0.084722 (rank : 27)	θ value	2.36792 (rank : 31)
Query Neighborhood Hits	44	Target Neighborhood Hits	30	Shared Neighborhood Hits	14
SwissProt Accessions	P55060, O75432, Q32M40, Q9H5B7, Q9NTS0, Q9UP98, Q9UP99, Q9UPA0	Gene names	CSE1L, CAS, XPO2
Domain Architecture
Description	Exportin-2 (Exp2) (Importin-alpha re-exporter) (Chromosome segregation 1-like protein) (Cellular apoptosis susceptibility protein).

XPO2_MOUSE
NC score	0.071970 (rank : 28)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	44	Target Neighborhood Hits	27	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ERK4	Gene names	Cse1l, Xpo2
Domain Architecture
Description	Exportin-2 (Exp2) (Importin-alpha re-exporter) (Chromosome segregation 1-like protein).

ECM29_MOUSE
NC score	0.067272 (rank : 29)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	44	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q6PDI5, Q6ZQC9, Q8BSW7, Q8CAH0, Q8R3M6	Gene names	Ecm29, Kiaa0368
Domain Architecture	No domain graphic available
Description	Proteasome-associated protein ECM29 homolog (Ecm29).

SF3B1_HUMAN
NC score	0.059892 (rank : 30)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	44	Target Neighborhood Hits	341	Shared Neighborhood Hits	15
SwissProt Accessions	O75533	Gene names	SF3B1, SAP155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

TRRAP_HUMAN
NC score	0.059061 (rank : 31)	θ value	0.21417 (rank : 21)
Query Neighborhood Hits	44	Target Neighborhood Hits	117	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

SF3B1_MOUSE
NC score	0.058316 (rank : 32)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	44	Target Neighborhood Hits	352	Shared Neighborhood Hits	16
SwissProt Accessions	Q99NB9, Q9CSK5	Gene names	Sf3b1, Sap155
Domain Architecture
Description	Splicing factor 3B subunit 1 (Spliceosome-associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA-splicing factor SF3b 155 kDa subunit).

PSMD5_MOUSE
NC score	0.029149 (rank : 33)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	44	Target Neighborhood Hits	15	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJY1, Q3UFV2, Q8BMA9, Q8VEE9	Gene names	Psmd5
Domain Architecture	No domain graphic available
Description	26S proteasome non-ATPase regulatory subunit 5 (26S proteasome subunit S5B) (26S protease subunit S5 basic).

C10_HUMAN
NC score	0.025116 (rank : 34)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	44	Target Neighborhood Hits	3	Shared Neighborhood Hits	2
SwissProt Accessions	Q99622	Gene names	C12orf57, C10
Domain Architecture	No domain graphic available
Description	Putative C10 protein.

HEAT1_HUMAN
NC score	0.023208 (rank : 35)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	44	Target Neighborhood Hits	52	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H583, Q5T3Q8, Q9NW23	Gene names	HEATR1, BAP28
Domain Architecture	No domain graphic available
Description	HEAT repeat-containing protein 1 (Protein BAP28).

FBX4_MOUSE
NC score	0.018651 (rank : 36)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	44	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CHQ0, Q99JG8	Gene names	Fbxo4, Fbx4
Domain Architecture	No domain graphic available
Description	F-box only protein 4.

SCYL2_MOUSE
NC score	0.017743 (rank : 37)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	44	Target Neighborhood Hits	603	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CFE4, Q3UT57, Q3UWU9, Q8K0M4	Gene names	Scyl2, Cvak104, D10Ertd802e
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

SCYL2_HUMAN
NC score	0.017253 (rank : 38)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	44	Target Neighborhood Hits	632	Shared Neighborhood Hits	5
SwissProt Accessions	Q6P3W7, Q96EF4, Q96ST4, Q9H7V5, Q9NVH3, Q9P2I7	Gene names	SCYL2, CVAK104, KIAA1360
Domain Architecture	No domain graphic available
Description	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa).

K0423_MOUSE
NC score	0.016902 (rank : 39)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	44	Target Neighborhood Hits	115	Shared Neighborhood Hits	8
SwissProt Accessions	Q6A070	Gene names	Kiaa0423
Domain Architecture	No domain graphic available
Description	Protein KIAA0423.

IMA2_HUMAN
NC score	0.016441 (rank : 40)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	44	Target Neighborhood Hits	51	Shared Neighborhood Hits	3
SwissProt Accessions	P52292, Q9BRU5	Gene names	KPNA2, RCH1, SRP1
Domain Architecture
Description	Importin alpha-2 subunit (Karyopherin alpha-2 subunit) (SRP1-alpha) (RAG cohort protein 1).

STAU1_HUMAN
NC score	0.011979 (rank : 41)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	44	Target Neighborhood Hits	45	Shared Neighborhood Hits	2
SwissProt Accessions	O95793, Q6GTM4, Q9H5B4, Q9H5B5, Q9Y3Q2	Gene names	STAU1, STAU
Domain Architecture
Description	Double-stranded RNA-binding protein Staufen homolog 1.

AP2B1_MOUSE
NC score	0.009214 (rank : 42)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	44	Target Neighborhood Hits	58	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBG3, Q80XJ4	Gene names	Ap2b1, Clapb1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

AP2B1_HUMAN
NC score	0.009213 (rank : 43)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	44	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	P63010, P21851, Q96J19	Gene names	AP2B1, CLAPB1
Domain Architecture	No domain graphic available
Description	AP-2 complex subunit beta-1 (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta large chain) (AP105B).

DYH5_HUMAN
NC score	0.006298 (rank : 44)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	44	Target Neighborhood Hits	323	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TE73, Q92860, Q96L74, Q9H5S7, Q9HCG9	Gene names	DNAH5, DNAHC5, KIAA1603
Domain Architecture	No domain graphic available
Description	Ciliary dynein heavy chain 5 (Axonemal beta dynein heavy chain 5) (HL1).